Plamen P. Christov, Ph.D. - Publications

Affiliations: 
2007 Vanderbilt University, Nashville, TN 
Area:
Organic Chemistry

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fu Y, Christov PP, Kingsley PJ, Richie-Jannetta RM, Marnett LJ, Stone MP. Base-Displaced Intercalated Structure of the 3-(2-Deoxy-β-D-erythropentofuranosyl)-pyrimido[1,2-]purine-6,10(3,5)-dione (6-oxo-MdG) Lesion in DNA. Chemical Research in Toxicology. PMID 37989274 DOI: 10.1021/acs.chemrestox.3c00226  0.395
2021 Christov PP, Richie-Jannetta R, Kingsley PJ, Vemulapalli A, Kim K, Sulikowski GA, Rizzo CJ, Ketkar A, Eoff RL, Rouzer CA, Marnett LJ. Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-MdG, the Genomic Metabolite of MdG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ι. Chemical Research in Toxicology. PMID 34860508 DOI: 10.1021/acs.chemrestox.1c00334  0.581
2020 Bradley NP, Washburn LA, Christov PP, Watanabe CMH, Eichman BF. Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks. Nucleic Acids Research. PMID 32409837 DOI: 10.1093/Nar/Gkaa346  0.514
2018 Minko IG, Christov PP, Li L, Stone MP, McCullough AK, Lloyd RS. Processing of N-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3. Dna Repair. PMID 30448017 DOI: 10.1016/J.Dnarep.2018.11.001  0.547
2017 Lepesheva G, Christov P, Sulikowski GA, Kim K. A convergent, scalable and stereoselective synthesis of azole CYP51 inhibitors. Tetrahedron Letters. 58: 4248-4250. PMID 29371747 DOI: 10.1016/J.Tetlet.2017.09.070  0.305
2015 Gruppi F, Hejazi L, Christov PP, Krishnamachari S, Turesky RJ, Rizzo CJ. Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell line. Chemical Research in Toxicology. 28: 1850-60. PMID 26285869 DOI: 10.1021/Acs.Chemrestox.5B00297  0.564
2015 Patra A, Banerjee S, Johnson Salyard TL, Malik CK, Christov PP, Rizzo CJ, Stone MP, Egli M. Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV. Journal of the American Chemical Society. 137: 7011-4. PMID 25988947 DOI: 10.1021/Jacs.5B02701  0.694
2015 Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, et al. Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo. Nucleic Acids Research. 43: 5489-500. PMID 25837992 DOI: 10.1093/Nar/Gkv243  0.664
2014 Christov PP, Son KJ, Rizzo CJ. Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine. Chemical Research in Toxicology. 27: 1610-8. PMID 25136769 DOI: 10.1021/Tx5002354  0.675
2014 Fu Y, Nath RG, Dyba M, Cruz IM, Pondicherry SR, Fernandez A, Schultz CL, Yang P, Pan J, Desai D, Krzeminski J, Amin S, Christov PP, Hara Y, Chung FL. In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation. Free Radical Biology & Medicine. 73: 12-20. PMID 24816294 DOI: 10.1016/J.Freeradbiomed.2014.04.032  0.459
2013 Rubinson EH, Christov PP, Eichman BF. Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone. Biochemistry. 52: 7363-5. PMID 24090276 DOI: 10.1021/Bi401195R  0.561
2013 Shanmugam G, Minko IG, Banerjee S, Christov PP, Kozekov ID, Rizzo CJ, Lloyd RS, Egli M, Stone MP. Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4. Chemical Research in Toxicology. 26: 1348-60. PMID 23947567 DOI: 10.1021/Tx400200B  0.66
2013 Christov PP, Hawkins EK, Kett NR, Rizzo CJ. Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosine. Tetrahedron Letters. 54: 4289-4291. PMID 23935223 DOI: 10.1016/J.Tetlet.2013.06.004  0.548
2013 Mullins EA, Rubinson EH, Pereira KN, Calcutt MW, Christov PP, Eichman BF. An HPLC-tandem mass spectrometry method for simultaneous detection of alkylated base excision repair products. Methods (San Diego, Calif.). 64: 59-66. PMID 23876937 DOI: 10.1016/J.Ymeth.2013.07.020  0.539
2013 Earley LF, Minko IG, Christov PP, Rizzo CJ, Lloyd RS. Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N(5)-methyl formamidopyrimidine adduct in primate cells. Chemical Research in Toxicology. 26: 1108-14. PMID 23763662 DOI: 10.1021/Tx4001495  0.673
2012 Zhao L, Pence MG, Christov PP, Wawrzak Z, Choi JY, Rizzo CJ, Egli M, Guengerich FP. Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases. The Journal of Biological Chemistry. 287: 35516-26. PMID 22910910 DOI: 10.1074/Jbc.M112.403253  0.654
2012 Christov PP, Yamanaka K, Choi JY, Takata K, Wood RD, Guengerich FP, Lloyd RS, Rizzo CJ. Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases. Chemical Research in Toxicology. 25: 1652-61. PMID 22721435 DOI: 10.1021/Tx300113E  0.679
2012 Zhao L, Christov PP, Kozekov ID, Pence MG, Pallan PS, Rizzo CJ, Egli M, Guengerich FP. Replication of N2,3-ethenoguanine by DNA polymerases. Angewandte Chemie (International Ed. in English). 51: 5466-9. PMID 22488769 DOI: 10.1002/Anie.201109004  0.701
2012 Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP. Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chemical Research in Toxicology. 25: 422-35. PMID 22313351 DOI: 10.1021/Tx200460J  0.644
2011 Harris CM, Stec DF, Christov PP, Kozekov ID, Rizzo CJ, Harris TM. Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene. Chemical Research in Toxicology. 24: 1944-56. PMID 21972945 DOI: 10.1021/Tx2002838  0.606
2010 Christov PP, Banerjee S, Stone MP, Rizzo CJ. Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. Journal of Nucleic Acids. 2010. PMID 20798848 DOI: 10.4061/2010/850234  0.53
2010 Christov PP, Petrova KV, Shanmugam G, Kozekov ID, Kozekova A, Guengerich FP, Stone MP, Rizzo CJ. Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Chemical Research in Toxicology. 23: 1330-41. PMID 20578729 DOI: 10.1021/Tx100082E  0.655
2010 Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Chemical Research in Toxicology. 23: 1076-88. PMID 20377178 DOI: 10.1021/Tx100053N  0.634
2010 Liu M, Bandaru V, Bond JP, Jaruga P, Zhao X, Christov PP, Burrows CJ, Rizzo CJ, Dizdaroglu M, Wallace SS. The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 107: 4925-4930. PMID 20185759 DOI: 10.1073/Pnas.0908307107  0.674
2009 Christov PP, Angel KC, Guengerich FP, Rizzo CJ. Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry. Chemical Research in Toxicology. 22: 1086-95. PMID 19397282 DOI: 10.1021/Tx900047C  0.66
2008 Christov PP, Brown KL, Kozekov ID, Stone MP, Harris TM, Rizzo CJ. Site-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine. Chemical Research in Toxicology. 21: 2324-33. PMID 19053322 DOI: 10.1021/Tx800352A  0.633
2008 Christov PP, Kozekov ID, Rizzo CJ, Harris TM. The formamidopyrimidine derivative of 7-(2-oxoethyl)-2'-deoxyguanosine. Chemical Research in Toxicology. 21: 1777-86. PMID 18690723 DOI: 10.1021/Tx800142M  0.633
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