| Year |
Citation |
Score |
| 2019 |
Streeter CC, Lin Q, Firestine SM. Isatins Inhibit N5-CAIR Synthetase by a Substrate Depletion Mechanism. Biochemistry. PMID 30964980 DOI: 10.1021/Acs.Biochem.8B00939 |
0.448 |
|
| 2018 |
Costabile G, Gasteyer KI, Nadithe V, Van Denburgh K, Lin Q, Sharma S, Reineke JJ, Firestine SM, Merkel OM. Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles. Aaps Pharmscitech. PMID 30255472 DOI: 10.1208/S12249-018-1187-9 |
0.336 |
|
| 2018 |
Sharma SK, Yip C, Esposito EX, Sharma PV, Simon MP, Abel-Santos E, Firestine SM. The Design, Synthesis and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile. Journal of Medicinal Chemistry. PMID 30004695 DOI: 10.1021/Acs.Jmedchem.8B00632 |
0.326 |
|
| 2013 |
Dewal MB, Firestine SM. Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase. Biochemistry. 52: 6559-67. PMID 23899325 DOI: 10.1021/Bi400444Y |
0.737 |
|
| 2013 |
Islam S, Firestine SM. Synthesis of substituted pyridyl-pyrimidines as potential protein-protein interaction inhibitors Journal of Heterocyclic Chemistry. 50: 1043-1048. DOI: 10.1002/Jhet.1595 |
0.317 |
|
| 2012 |
Dewal MB, Wani AS, Vidaillac C, Oupický D, Rybak MJ, Firestine SM. Thieno[2,3-d]pyrimidinedione derivatives as antibacterial agents. European Journal of Medicinal Chemistry. 51: 145-53. PMID 22405289 DOI: 10.1016/J.Ejmech.2012.02.035 |
0.747 |
|
| 2011 |
Fawaz MV, Topper ME, Firestine SM. The ATP-grasp enzymes. Bioorganic Chemistry. 39: 185-91. PMID 21920581 DOI: 10.1016/J.Bioorg.2011.08.004 |
0.375 |
|
| 2011 |
Vooturi SK, Dewal MB, Firestine SM. Examination of a synthetic benzophenone membrane-targeted antibiotic. Organic & Biomolecular Chemistry. 9: 6367-72. PMID 21792399 DOI: 10.1039/C1Ob05643C |
0.721 |
|
| 2011 |
Dewal MB, Firestine SM. Non-peptidic α-helical mimetics as protein-protein interaction inhibitors. Current Medicinal Chemistry. 18: 2420-8. PMID 21568916 DOI: 10.2174/092986711795843227 |
0.71 |
|
| 2010 |
Vooturi SK, Firestine SM. Synthetic membrane-targeted antibiotics. Current Medicinal Chemistry. 17: 2292-300. PMID 20459377 DOI: 10.2174/092986710791331059 |
0.734 |
|
| 2010 |
Paritala H, Firestine SM. Characterization of insulin ILPR sequences for their ability to adopt a G-quadruplex structure. Nucleosides, Nucleotides & Nucleic Acids. 29: 81-90. PMID 20391195 DOI: 10.1080/15257771003597691 |
0.711 |
|
| 2010 |
Thoden JB, Holden HM, Paritala H, Firestine SM. Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase . Biochemistry. 49: 752-60. PMID 20050602 DOI: 10.1021/Bi901599U |
0.749 |
|
| 2010 |
Vooturi SK, Firestine SM. Solution-phase parallel synthesis of novel membrane-targeted antibiotics. Journal of Combinatorial Chemistry. 12: 151-60. PMID 19928911 DOI: 10.1021/Cc900138H |
0.766 |
|
| 2009 |
Vooturi SK, Cheung CM, Rybak MJ, Firestine SM. Design, synthesis, and structure-activity relationships of benzophenone-based tetraamides as novel antibacterial agents. Journal of Medicinal Chemistry. 52: 5020-31. PMID 19653650 DOI: 10.1021/Jm900519B |
0.769 |
|
| 2009 |
Firestine SM, Paritala H, McDonnell JE, Thoden JB, Holden HM. Identification of inhibitors of N5-carboxyaminoimidazole ribonucleotide synthetase by high-throughput screening. Bioorganic & Medicinal Chemistry. 17: 3317-23. PMID 19362848 DOI: 10.1016/J.Bmc.2009.03.043 |
0.757 |
|
| 2009 |
Paritala H, Firestine SM. Benzo(h)quinoline derivatives as G-quadruplex binding agents. Bioorganic & Medicinal Chemistry Letters. 19: 1584-7. PMID 19243943 DOI: 10.1016/J.Bmcl.2009.02.016 |
0.749 |
|
| 2009 |
Firestine SM, Wu W, Youn H, Davisson VJ. Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase. Bioorganic & Medicinal Chemistry. 17: 794-803. PMID 19095456 DOI: 10.1016/J.Bmc.2008.11.057 |
0.649 |
|
| 2008 |
Thoden JB, Holden HM, Firestine SM. Structural analysis of the active site geometry of N5-carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli. Biochemistry. 47: 13346-53. PMID 19053251 DOI: 10.1021/Bi801734Z |
0.378 |
|
| 2006 |
Hooda J, Bednarski D, Irish L, Firestine SM. Synthesis and testing of a triaza-cyclopenta[b]phenanthrene scaffold as a DNA binding agent. Bioorganic & Medicinal Chemistry. 14: 1902-9. PMID 16298133 DOI: 10.1016/J.Bmc.2005.10.047 |
0.406 |
|
| 2006 |
Mamidyala SK, Firestine SM. Advances in herpes simplex virus antiviral therapies Expert Opinion On Therapeutic Patents. 16: 1463-1480. DOI: 10.1517/13543776.16.11.1463 |
0.339 |
|
| 2006 |
Mamidyala SK, Firestine SM. Fluorous synthesis of minor groove binding agents related to distamycin Tetrahedron Letters. 47: 7431-7434. DOI: 10.1016/J.Tetlet.2006.08.058 |
0.376 |
|
| 1998 |
Firestine SM, Misialek S, Toffaletti DL, Klem TJ, Perfect JR, Davisson VJ. Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis. Archives of Biochemistry and Biophysics. 351: 123-34. PMID 9500840 DOI: 10.1006/Abbi.1997.0512 |
0.621 |
|
| 1994 |
Firestine SM, Poon SW, Mueller EJ, Stubbe J, Davisson VJ. Reactions catalyzed by 5-aminoimidazole ribonucleotide carboxylases from Escherichia coli and Gallus gallus: a case for divergent catalytic mechanisms. Biochemistry. 33: 11927-34. PMID 7918411 DOI: 10.1021/Bi00205A031 |
0.593 |
|
| 1994 |
Firestine SM, Davisson VJ. Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme. Biochemistry. 33: 11917-26. PMID 7918410 |
0.609 |
|
| 1993 |
Firestine SM, Davisson VJ. A tight binding inhibitor of 5-aminoimidazole ribonucleotide carboxylase. Journal of Medicinal Chemistry. 36: 3484-6. PMID 8230140 DOI: 10.1021/Jm00074A033 |
0.549 |
|
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