Kevin D. Sarge - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Biochemistry, Cell Biology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sarge KD. Analysis of Protein Sumoylation. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 83: 14.8.1-8. PMID 26836406 DOI: 10.1002/0471140864.Ps1408S83  0.453
2013 Gandhapudi SK, Murapa P, Threlkeld ZD, Ward M, Sarge KD, Snow C, Woodward JG. Heat shock transcription factor 1 is activated as a consequence of lymphocyte activation and regulates a major proteostasis network in T cells critical for cell division during stress. Journal of Immunology (Baltimore, Md. : 1950). 191: 4068-79. PMID 24043900 DOI: 10.4049/Jimmunol.1202831  0.404
2011 Sarge KD, Park-Sarge OK. SUMO and its role in human diseases. International Review of Cell and Molecular Biology. 288: 167-83. PMID 21482412 DOI: 10.1016/B978-0-12-386041-5.00004-2  0.346
2010 Xing H, Hong Y, Sarge KD. PEST sequences mediate heat shock factor 2 turnover by interacting with the Cul3 subunit of the Cul3-RING ubiquitin ligase. Cell Stress & Chaperones. 15: 301-8. PMID 19768582 DOI: 10.1007/S12192-009-0144-7  0.493
2009 Sarge KD, Park-Sarge OK. Detection of proteins sumoylated in vivo and in vitro. Methods in Molecular Biology (Clifton, N.J.). 590: 265-77. PMID 19763510 DOI: 10.1007/978-1-60327-378-7_17  0.447
2009 Sarge KD, Xing H, Park-Sarge OK. Chromosome-wide analysis of protein binding and modifications. Methods in Molecular Biology (Clifton, N.J.). 590: 223-33. PMID 19763507 DOI: 10.1007/978-1-60327-378-7_14  0.398
2009 Wilkerson DC, Sarge KD. RNA polymerase II interacts with the Hspa1b promoter in mouse epididymal spermatozoa. Reproduction (Cambridge, England). 137: 923-9. PMID 19336471 DOI: 10.1530/Rep-09-0015  0.411
2009 Sarge KD, Park-Sarge OK. Sumoylation and human disease pathogenesis. Trends in Biochemical Sciences. 34: 200-5. PMID 19282183 DOI: 10.1016/J.Tibs.2009.01.004  0.355
2009 Zhang J, Sarge KD. Identification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome system. Febs Letters. 583: 960-4. PMID 19233177 DOI: 10.1016/J.Febslet.2009.02.023  0.32
2009 Sarge KD, Park-Sarge OK. Mitotic bookmarking of formerly active genes: keeping epigenetic memories from fading. Cell Cycle (Georgetown, Tex.). 8: 818-23. PMID 19221503 DOI: 10.4161/Cc.8.6.7849  0.384
2009 Park-Sarge OK, Sarge KD. Detection of sumoylated proteins. Methods in Molecular Biology (Clifton, N.J.). 464: 255-65. PMID 18951189 DOI: 10.1007/978-1-60327-461-6_14  0.343
2008 Murphy LA, Sarge KD. Phosphorylation of CAP-G is required for its chromosomal DNA localization during mitosis. Biochemical and Biophysical Research Communications. 377: 1007-11. PMID 18977199 DOI: 10.1016/J.Bbrc.2008.10.114  0.351
2008 Xing H, Vanderford NL, Sarge KD. The TBP-PP2A mitotic complex bookmarks genes by preventing condensin action. Nature Cell Biology. 10: 1318-23. PMID 18931662 DOI: 10.1038/Ncb1790  0.445
2008 Zhang J, Sarge KD. Mel-18 interacts with RanGAP1 and inhibits its sumoylation. Biochemical and Biophysical Research Communications. 375: 252-5. PMID 18706886 DOI: 10.1016/J.Bbrc.2008.08.012  0.51
2008 Zhang YQ, Sarge KD. Sumoylation of amyloid precursor protein negatively regulates Abeta aggregate levels. Biochemical and Biophysical Research Communications. 374: 673-8. PMID 18675254 DOI: 10.1016/J.Bbrc.2008.07.109  0.352
2008 Zhang YQ, Sarge KD. Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies. The Journal of Cell Biology. 182: 35-9. PMID 18606848 DOI: 10.1083/Jcb.200712124  0.326
2008 Murphy LA, Wilkerson DC, Hong Y, Sarge KD. PRC1 associates with the hsp70i promoter and interacts with HSF2 during mitosis. Experimental Cell Research. 314: 2224-30. PMID 18570919 DOI: 10.1016/J.Yexcr.2008.04.015  0.502
2008 Wilkerson DC, Murphy LA, Sarge KD. Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa. Biology of Reproduction. 79: 283-8. PMID 18434628 DOI: 10.1095/Biolreprod.107.066241  0.456
2008 Zhang J, Goodson ML, Hong Y, Sarge KD. MEL-18 interacts with HSF2 and the SUMO E2 UBC9 to inhibit HSF2 sumoylation. The Journal of Biological Chemistry. 283: 7464-9. PMID 18211895 DOI: 10.1074/Jbc.M707122200  0.513
2007 Murapa P, Gandhapudi S, Skaggs HS, Sarge KD, Woodward JG. Physiological fever temperature induces a protective stress response in T lymphocytes mediated by heat shock factor-1 (HSF1). Journal of Immunology (Baltimore, Md. : 1950). 179: 8305-12. PMID 18056375 DOI: 10.4049/Jimmunol.179.12.8305  0.36
2007 Zhang YQ, Sarge KD. Celastrol inhibits polyglutamine aggregation and toxicity though induction of the heat shock response. Journal of Molecular Medicine (Berlin, Germany). 85: 1421-8. PMID 17943263 DOI: 10.1007/S00109-007-0251-9  0.448
2007 Wilkerson DC, Skaggs HS, Sarge KD. HSF2 binds to the Hsp90, Hsp27, and c-Fos promoters constitutively and modulates their expression. Cell Stress & Chaperones. 12: 283-90. PMID 17915561 DOI: 10.1379/Csc-250.1  0.496
2007 Skaggs HS, Xing H, Wilkerson DC, Murphy LA, Hong Y, Mayhew CN, Sarge KD. HSF1-TPR interaction facilitates export of stress-induced HSP70 mRNA. The Journal of Biological Chemistry. 282: 33902-7. PMID 17897941 DOI: 10.1074/Jbc.M704054200  0.429
2007 Xing H, Hong Y, Sarge KD. Identification of the PP2A-interacting region of heat shock transcription factor 2. Cell Stress & Chaperones. 12: 192-7. PMID 17688198 DOI: 10.1379/Csc-249R.1  0.513
2006 Hilgarth RS, Sarge KD. Analysis of protein sumoylation. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 14.8. PMID 18429298 DOI: 10.1002/0471140864.Ps1408S44  0.44
2005 Sarge KD, Park-Sarge OK. Gene bookmarking: keeping the pages open. Trends in Biochemical Sciences. 30: 605-10. PMID 16188444 DOI: 10.1016/J.Tibs.2005.09.004  0.402
2005 Hilgarth RS, Sarge KD. Detection of sumoylated proteins. Methods in Molecular Biology (Clifton, N.J.). 301: 329-38. PMID 15917643 DOI: 10.1385/1-59259-895-1:329  0.422
2005 Alimov AP, Park-Sarge OK, Sarge KD, Malluche HH, Koszewski NJ. Transactivation of the parathyroid hormone promoter by specificity proteins and the nuclear factor Y complex. Endocrinology. 146: 3409-16. PMID 15890770 DOI: 10.1210/En.2005-0272  0.394
2005 Xing H, Wilkerson DC, Mayhew CN, Lubert EJ, Skaggs HS, Goodson ML, Hong Y, Park-Sarge OK, Sarge KD. Mechanism of hsp70i gene bookmarking. Science (New York, N.Y.). 307: 421-3. PMID 15662014 DOI: 10.1126/Science.1106478  0.729
2004 Hilgarth RS, Murphy LA, O'Connor CM, Clark JA, Park-Sarge OK, Sarge KD. Identification of Xenopus heat shock transcription factor-2: conserved role of sumoylation in regulating deoxyribonucleic acid-binding activity of heat shock transcription factor-2 proteins. Cell Stress & Chaperones. 9: 214-20. PMID 15497507 DOI: 10.1379/Csc-8R.1  0.534
2004 Hilgarth RS, Murphy LA, Skaggs HS, Wilkerson DC, Xing H, Sarge KD. Regulation and function of SUMO modification. The Journal of Biological Chemistry. 279: 53899-902. PMID 15448161 DOI: 10.1074/Jbc.R400021200  0.467
2004 Xing H, Mayhew CN, Cullen KE, Park-Sarge OK, Sarge KD. HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin. The Journal of Biological Chemistry. 279: 10551-5. PMID 14707147 DOI: 10.1074/Jbc.M311719200  0.524
2003 Lubert EJ, Sarge KD. Interaction between protein phosphatase 2A and members of the importin beta superfamily. Biochemical and Biophysical Research Communications. 303: 908-13. PMID 12670497 DOI: 10.1016/S0006-291X(03)00434-0  0.724
2003 Hilgarth RS, Hong Y, Park-Sarge OK, Sarge KD. Insights into the regulation of heat shock transcription factor 1 SUMO-1 modification. Biochemical and Biophysical Research Communications. 303: 196-200. PMID 12646186 DOI: 10.1016/S0006-291X(03)00312-7  0.477
2003 Gothard LQ, Ruffner ME, Woodward JG, Park-Sarge OK, Sarge KD. Lowered temperature set point for activation of the cellular stress response in T-lymphocytes. The Journal of Biological Chemistry. 278: 9322-6. PMID 12519785 DOI: 10.1074/Jbc.M209412200  0.37
2001 Guo C, Savage L, Sarge KD, Park-Sarge OK. Gonadotropins Decrease Estrogen Receptor-β Messenger Ribonucleic Acid Stability in Rat Granulosa Cells. Endocrinology. 142: 2230-2237. PMID 28201364 DOI: 10.1210/Endo.142.6.8102  0.322
2001 Hong Y, Rogers R, Matunis MJ, Mayhew CN, Goodson ML, Park-Sarge OK, Sarge KD, Goodson M. Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification. The Journal of Biological Chemistry. 276: 40263-7. PMID 11514557 DOI: 10.1074/Jbc.M104714200  0.462
2001 Lubert EJ, Hong Y, Sarge KD. Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5. The Journal of Biological Chemistry. 276: 38582-7. PMID 11504734 DOI: 10.1074/Jbc.M106906200  0.733
2001 Goodson ML, Hong Y, Rogers R, Matunis MJ, Park-Sarge OK, Sarge KD. Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factor. The Journal of Biological Chemistry. 276: 18513-8. PMID 11278381 DOI: 10.1074/Jbc.M008066200  0.501
2001 Graham KM, Ko C, Park KS, Sarge K, Park-Sarge OK. Expression of an intracisternal A-particle-like element in rat ovary. Biochemical and Biophysical Research Communications. 278: 48-57. PMID 11071854 DOI: 10.1006/Bbrc.2000.3759  0.355
2000 Hong Y, Lubert EJ, Rodgers DW, Sarge KD. Molecular basis of competition between HSF2 and catalytic subunit for binding to the PR65/A subunit of PP2A Biochemical and Biophysical Research Communications. 272: 84-89. PMID 10872807 DOI: 10.1006/Bbrc.2000.2733  0.734
2000 Heydari AR, You S, Takahashi R, Gutsmann-Conrad A, Sarge KD, Richardson A. Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes. Experimental Cell Research. 256: 83-93. PMID 10739655 DOI: 10.1006/Excr.2000.4808  0.394
1999 Hong Y, Sarge KD. Regulation of protein phosphatase 2A activity by heat shock transcription factor 2. The Journal of Biological Chemistry. 274: 12967-70. PMID 10224043 DOI: 10.1074/Jbc.274.19.12967  0.587
1998 Sarge KD. Regulation of HSF1 activation and Hsp expression in mouse tissues under physiological stress conditions. Annals of the New York Academy of Sciences. 851: 112-6. PMID 9668612 DOI: 10.1111/J.1749-6632.1998.Tb08983.X  0.333
1998 Outinen PA, Sood SK, Liaw PC, Sarge KD, Maeda N, Hirsh J, Ribau J, Podor TJ, Weitz JI, Austin RC. Characterization of the stress-inducing effects of homocysteine. The Biochemical Journal. 332: 213-21. PMID 9576870 DOI: 10.1042/Bj3320213  0.416
1997 Hansen RK, Oesterreich S, Lemieux P, Sarge KD, Fuqua SA. Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells. Biochemical and Biophysical Research Communications. 239: 851-6. PMID 9367858 DOI: 10.1006/Bbrc.1997.7572  0.419
1997 Leppä S, Pirkkala L, Saarento H, Sarge KD, Sistonen L. Overexpression of HSF2-beta inhibits hemin-induced heat shock gene expression and erythroid differentiation in K562 cells. The Journal of Biological Chemistry. 272: 15293-8. PMID 9182556 DOI: 10.1074/Jbc.272.24.15293  0.416
1997 Sarge KD, Cullen KE. Regulation of hsp expression during rodent spermatogenesis. Cellular and Molecular Life Sciences : Cmls. 53: 191-7. PMID 9118007 DOI: 10.1007/Pl00000591  0.442
1997 Cullen KE, Sarge KD. Characterization of hypothermia-induced cellular stress response in mouse tissues. The Journal of Biological Chemistry. 272: 1742-6. PMID 8999855 DOI: 10.1074/Jbc.272.3.1742  0.394
1996 Heydari AR, You S, Takahashi R, Gutsmann A, Sarge KD, Richardson A. Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1. Developmental Genetics. 18: 114-24. PMID 8934873 DOI: 10.1002/(Sici)1520-6408(1996)18:2<114::Aid-Dvg4>3.0.Co;2-C  0.427
1995 Goodson ML, Sarge KD. Heat-inducible DNA binding of purified heat shock transcription factor 1 Journal of Biological Chemistry. 270: 2447-2450. PMID 7852305 DOI: 10.1074/Jbc.270.6.2447  0.477
1995 Sarge KD. Male germ cell-specific alteration in temperature set point of the cellular stress response. The Journal of Biological Chemistry. 270: 18745-8. PMID 7642523 DOI: 10.1074/Jbc.270.32.18745  0.417
1995 Goodson ML, Sarge KD. Regulated Expression of Heat Shock Factor 1 Isoforms with Distinct Leucine Zipper Arrays via Tissue-Dependent Alternative Splicing Biochemical and Biophysical Research Communications. 211: 943-949. PMID 7598726 DOI: 10.1006/Bbrc.1995.1903  0.433
1995 Park-Sarge OK, Sarge KD. Cis-regulatory elements conferring cyclic 3',5'-adenosine monophosphate responsiveness of the progesterone receptor gene in transfected rat granulosa cells. Endocrinology. 136: 5430-7. PMID 7588292 DOI: 10.1210/Endo.136.12.7588292  0.413
1995 Goodson ML, Park-Sarge OK, Sarge KD. Tissue-dependent expression of heat shock factor 2 isoforms with distinct transcriptional activities Molecular and Cellular Biology. 15: 5288-5293. PMID 7565677 DOI: 10.1128/Mcb.15.10.5288  0.442
1994 Jurivich DA, Sistonen L, Sarge KD, Morimoto RI. Arachidonate is a potent modulator of human heat shock gene transcription. Proceedings of the National Academy of Sciences of the United States of America. 91: 2280-4. PMID 8134388 DOI: 10.1073/Pnas.91.6.2280  0.41
1994 Sistonen L, Sarge KD, Morimoto RI. Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription. Molecular and Cellular Biology. 14: 2087-99. PMID 8114740 DOI: 10.1128/mcb.14.3.2087-2099.1994  0.458
1994 Sarge KD, Park-Sarge OK, Kirby JD, Mayo KE, Morimoto RI. Expression of heat shock factor 2 in mouse testis: potential role as a regulator of heat-shock protein gene expression during spermatogenesis. Biology of Reproduction. 50: 1334-43. PMID 8080921 DOI: 10.1095/Biolreprod50.6.1334  0.484
1994 Mathur SK, Sistonen L, Brown IR, Murphy SP, Sarge KD, Morimoto RI. Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1. Proceedings of the National Academy of Sciences of the United States of America. 91: 8695-9. PMID 8078944 DOI: 10.1073/Pnas.91.18.8695  0.43
1994 Murphy SP, Gorzowski JJ, Sarge KD, Phillips B. Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells Molecular and Cellular Biology. 14: 5309-5317. PMID 8035809 DOI: 10.1128/Mcb.14.8.5309  0.462
1994 Morimoto RI, Jurivich DA, Kroeger PE, Mathur SK, Murphy SP, Nakai A, Sarge K, Abravaya K, Sistonen LT. 17 Regulation of Heat Shock Gene Transcription by a Family of Heat Shock Factors Cold Spring Harbor Monograph Archive. 26: 417-455. DOI: 10.1101/087969427.26.417  0.43
1993 Kroeger PE, Sarge KD, Morimoto RI. Mouse heat shock transcription factors 1 and 2 prefer a trimeric binding site but interact differently with the HSP70 heat shock element. Molecular and Cellular Biology. 13: 3370-83. PMID 8497256 DOI: 10.1128/mcb.13.6.3370-3383.1993  0.421
1993 Sarge KD, Murphy SP, Morimoto RI. Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress. Molecular and Cellular Biology. 13: 1392-407. PMID 8441385 DOI: 10.1128/mcb.13.3.1392-1407.1993  0.482
1992 Sarge KD, Maxwell ES. Evidence for a Competitive-Displacement Model for the initiation of protein synthesis involving the intermolecular hybridization of 5 S rRNA, 18 S rRNA and mRNA. Febs Letters. 294: 234-8. PMID 1756865 DOI: 10.1016/0014-5793(91)81437-D  0.319
1992 Sistonen L, Sarge KD, Phillips B, Abravaya K, Morimoto RI. Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells. Molecular and Cellular Biology. 12: 4104-11. PMID 1508207 DOI: 10.1128/mcb.12.9.4104-4111.1992  0.451
1991 Sarge KD, Zimarino V, Holm K, Wu C, Morimoto RI. Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability. Genes & Development. 5: 1902-11. PMID 1717345 DOI: 10.1101/Gad.5.10.1902  0.453
1990 Mosser DD, Kotzbauer PT, Sarge KD, Morimoto RI. In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation. Proceedings of the National Academy of Sciences of the United States of America. 87: 3748-52. PMID 2339118 DOI: 10.1073/Pnas.87.10.3748  0.46
1988 Maxwell ES, Sarge KD. A simple and rapid method for the preparation of homologous DNA oligonucleotide hybridization probes from heterologous gene sequences and probes. Biochemical and Biophysical Research Communications. 157: 154-9. PMID 2461708 DOI: 10.1016/S0006-291X(88)80026-3  0.303
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