| Year |
Citation |
Score |
| 2015 |
Seneviratne D, Ma J, Tan X, Kwon YK, Muhammad E, Melhem M, DeFrances MC, Zarnegar R. Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis. Gastroenterology. 148: 181-191.e17. PMID 25244939 DOI: 10.1053/J.Gastro.2014.09.019 |
0.386 |
|
| 2014 |
Ma J, Zou C, Guo L, Seneviratne DS, Tan X, Kwon YK, An J, Bowser R, DeFrances MC, Zarnegar R. Novel Death Defying Domain in Met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes. Hepatology (Baltimore, Md.). 59: 2010-21. PMID 24122846 DOI: 10.1002/Hep.26769 |
0.363 |
|
| 2009 |
Dai JY, DeFrances MC, Zou C, Johnson CJ, Zarnegar R. The Met protooncogene is a transcriptional target of NF kappaB: implications for cell survival. Journal of Cellular Biochemistry. 107: 1222-36. PMID 19530226 DOI: 10.1002/Jcb.22226 |
0.4 |
|
| 2009 |
Ma J, DeFrances MC, Zou C, Johnson C, Ferrell R, Zarnegar R. Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer Journal of Clinical Investigation. 119: 478-491. PMID 19188684 DOI: 10.1172/Jci36640 |
0.321 |
|
| 2007 |
Zou C, Ma J, Wang X, Guo L, Zhu Z, Stoops J, Eaker AE, Johnson CJ, Strom S, Michalopoulos GK, DeFrances MC, Zarnegar R. Lack of Fas antagonism by Met in human fatty liver disease. Nature Medicine. 13: 1078-85. PMID 17704785 DOI: 10.1038/Nm1625 |
0.351 |
|
| 2007 |
Zhao Y, Difrancesca D, Wang X, Zarnegar R, Michalopoulos GK, Yin XM. Promotion of Fas-mediated apoptosis in Type II cells by high doses of hepatocyte growth factor bypasses the mitochondrial requirement. Journal of Cellular Physiology. 213: 556-63. PMID 17620325 DOI: 10.1002/Jcp.21136 |
0.326 |
|
| 2004 |
Wang X, Zhou Y, Kim HP, Song R, Zarnegar R, Ryter SW, Choi AM. Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells. The Journal of Biological Chemistry. 279: 5237-43. PMID 14625309 DOI: 10.1074/Jbc.M309271200 |
0.377 |
|
| 2003 |
Mehdi H, Manzi S, Desai P, Chen Q, Nestlerode C, Bontempo F, Strom SC, Zarnegar R, Kamboh MI. A functional polymorphism at the transcriptional initiation site in beta2-glycoprotein I (apolipoprotein H) associated with reduced gene expression and lower plasma levels of beta2-glycoprotein I. European Journal of Biochemistry / Febs. 270: 230-8. PMID 12605674 DOI: 10.1046/J.1432-1033.2003.03379.X |
0.322 |
|
| 2002 |
Wang X, DeFrances MC, Dai Y, Pediaditakis P, Johnson C, Bell A, Michalopoulos GK, Zarnegar R. A mechanism of cell survival: sequestration of Fas by the HGF receptor Met. Molecular Cell. 9: 411-21. PMID 11864613 DOI: 10.1016/S1097-2765(02)00439-2 |
0.368 |
|
| 2001 |
Jiang J, Johnson C, Zarnegar R. Peroxisome proliferator-activated receptor gamma-mediated transcriptional up-regulation of the hepatocyte growth factor gene promoter via a novel composite cis-acting element. Journal of Biological Chemistry. 276: 25049-25056. PMID 11292834 DOI: 10.1074/Jbc.M101611200 |
0.457 |
|
| 2001 |
Elia G, Ren Y, Lorenzoni P, Zarnegar R, Burger MM, Rusciano D. Mechanisms regulating c-met overexpression in liver-metastatic B16-LS9 melanoma cells. Journal of Cellular Biochemistry. 81: 477-87. PMID 11255230 DOI: 10.1002/1097-4644(20010601)81:3<477::Aid-Jcb1061>3.0.Co;2-B |
0.403 |
|
| 2000 |
Jiang J, DeFrances MC, Machen J, Johnson C, Zarnegar R. The Repressive Function of AP2 Transcription Factor on the Hepatocyte Growth Factor Gene Promoter Biochemical and Biophysical Research Communications. 272: 882-886. PMID 10860846 DOI: 10.1006/Bbrc.2000.2848 |
0.44 |
|
| 2000 |
Jiang J, Gao B, Zarnegar R. The concerted regulatory functions of the transcription factors nuclear factor-1 and upstream stimulatory factor on a composite element in the promoter of the hepatocyte growth factor gene. Oncogene. 19: 2786-2790. PMID 10851080 DOI: 10.1038/Sj.Onc.1203581 |
0.404 |
|
| 2000 |
Seol DW, Chen Q, Zarnegar R. Transcriptional activation of the Hepatocyte Growth Factor receptor (c-met) gene by its ligand (Hepatocyte Growth Factor) is mediated through AP-1 Oncogene. 19: 1132-1137. PMID 10713700 DOI: 10.1038/Sj.Onc.1203404 |
0.432 |
|
| 1999 |
Bell A, Chen Q, DeFrances MC, Michalopoulos GK, Zarnegar R. The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic mice Oncogene. 18: 887-895. PMID 10023664 DOI: 10.1038/Sj.Onc.1202379 |
0.355 |
|
| 1999 |
Seol DW, Chen Q, Smith ML, Zarnegar R. Regulation of the c-met proto-oncogene promoter by p53 Journal of Biological Chemistry. 274: 3565-3572. PMID 9920903 DOI: 10.1074/Jbc.274.6.3565 |
0.335 |
|
| 1998 |
Seol DW, Zarnegar R. Structural and functional characterization of the mouse c-met proto- oncogene (Hepatocyte Growth Factor Receptor) promoter Biochimica Et Biophysica Acta - Gene Structure and Expression. 1395: 252-258. PMID 9512656 DOI: 10.1016/S0167-4781(97)00202-9 |
0.469 |
|
| 1998 |
Bell AW, Jiang JG, Chen Q, Liu Y, Zarnegar R. The upstream regulatory regions of the hepatocyte growth factor gene promoter are essential for its expression in transgenic mice. The Journal of Biological Chemistry. 273: 6900-8. PMID 9506994 DOI: 10.1074/Jbc.273.12.6900 |
0.437 |
|
| 1997 |
Jiang J, Chen Q, Bell A, Zarnegar R. Transcriptional regulation of the hepatocyte growth factor (HGF) gene by the Sp family of transcription factors Oncogene. 14: 3039-3049. PMID 9223667 DOI: 10.1038/Sj.Onc.1201152 |
0.394 |
|
| 1997 |
Chen Q, Seol DW, Carr B, Zarnegar R. Co-expression and regulation of met and ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines Hepatology. 26: 59-66. PMID 9214452 DOI: 10.1002/Hep.510260108 |
0.456 |
|
| 1997 |
Jiang J, Bell A, Liu Y, Zarnegar R. Transcriptional Regulation of the Hepatocyte Growth Factor Gene by the Nuclear Receptors Chicken Ovalbumin Upstream Promoter Transcription Factor and Estrogen Receptor Journal of Biological Chemistry. 272: 3928-3934. PMID 9020096 DOI: 10.1074/Jbc.272.7.3928 |
0.454 |
|
| 1995 |
Zarnegar R, Michalopoulos GK. The many faces of hepatocyte growth factor: From hepatopoiesis to hematopoiesis Journal of Cell Biology. 129: 1177-1180. PMID 7775566 DOI: 10.1083/Jcb.129.5.1177 |
0.328 |
|
| 1994 |
Liu ML, Mars WM, Zarnegar R, Michalopoulos GK. Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor-α in adult rat liver Hepatology. 19: 1521-1527. PMID 8188184 DOI: 10.1002/Hep.1840190630 |
0.377 |
|
| 1994 |
Liu Y, Bell AW, Michalopoulos GK, Zarnegar R. The mouse hepatocyte growth factor-encoding gene: structural organization and evolutionary conservation Gene. 144: 179-187. PMID 8039703 DOI: 10.1016/0378-1119(94)90376-X |
0.374 |
|
| 1994 |
Liu Y, Lin L, Zarnegar R. Modulation of hepatocyte growth factor gene expression by estrogen in mouse ovary Molecular and Cellular Endocrinology. 104: 173-181. PMID 7988745 DOI: 10.1016/0303-7207(94)90120-1 |
0.434 |
|
| 1994 |
Petersen B, Yee CJ, Bowen W, Zarnegar R, Michalopoulos GK. Distinct morphological and mito-inhibitory effects induced by TGF-β1, HGF and EGF on mouse, rat and human hepatocytes Cell Biology and Toxicology. 10: 219-230. PMID 7895151 DOI: 10.1007/Bf00756762 |
0.304 |
|
| 1994 |
Weir E, Chen Q, DeFrances MC, Bell A, Taub R, Zarnegar R. Rapid induction of mRNAs for liver regeneration factor and insulin-like growth factor binding protein-1 in primary cultures of rat hepatocytes by hepatocyte growth factor and epidermal growth factor. Hepatology (Baltimore, Md.). 20: 955-60. PMID 7523267 DOI: 10.1002/Hep.1840200426 |
0.432 |
|
| 1993 |
Yee CJ, Defrances MC, Bell A, Bowen W, Petersen B, Michalopoulos GK, Zarnegar R. Expression and characterization of biologically active human hepatocyte growth factor (HGF) by insect cells infected with HGF-recombinant baculovirus Biochemistry. 32: 7922-7931. PMID 8347597 DOI: 10.1021/Bi00082A013 |
0.389 |
|
| 1993 |
Liu Y, Michalopoulos GK, Zarnegar R. Molecular cloning and characterization of cDNA encoding mouse hepatocyte growth factor Bba - Gene Structure and Expression. 1216: 299-303. PMID 8241272 DOI: 10.1016/0167-4781(93)90159-B |
0.368 |
|
| 1992 |
Zarnegar R, Petersen B, DeFrances MC, Michalopoulos G. Localization of hepatocyte growth factor (HGF) gene on human chromosome 7. Genomics. 12: 147-50. PMID 1531136 DOI: 10.1016/0888-7543(92)90417-Q |
0.358 |
|
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