Year |
Citation |
Score |
2020 |
Yim TW, Perling D, Polcz M, Komalavilas P, Brophy C, Cheung-Flynn J. A cell permeant phosphopeptide mimetic of Niban inhibits p38 MAPK and restores endothelial function after injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32396246 DOI: 10.1096/Fj.201902745R |
0.378 |
|
2020 |
Yim TW, Perling D, Polcz M, Komalavilas P, Brophy C, Cheung-Flynn J. A cell permeant phosphopeptide mimetic of Niban restores endothelial function and inhibits p38 MAPK activation after vascular injury The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02968 |
0.313 |
|
2018 |
Hocking KM, Evans BC, Komalavilas P, Cheung-Flynn J, Duvall C, Brophy C. Nanotechnology Enabled Modulation of Signaling Pathways Affects Physiology in Intact Vascular Tissue. Tissue Engineering. Part A. PMID 30132374 DOI: 10.1089/Ten.Tea.2018.0169 |
0.359 |
|
2017 |
Luo W, Feldman D, McCallister R, Brophy C, Cheung-Flynn J. P2X7R antagonism after subfailure overstretch injury of blood vessels reverses vasomotor dysfunction and prevents apoptosis. Purinergic Signalling. PMID 28905300 DOI: 10.1007/S11302-017-9585-0 |
0.355 |
|
2016 |
Osgood MJ, Sexton K, Voskresensky I, Hocking K, Song J, Komalavilas P, Brophy C, Cheung-Flynn J. Use of Brilliant Blue FCF during vein graft preparation inhibits intimal hyperplasia. Journal of Vascular Surgery. 64: 471-478. PMID 27763268 DOI: 10.1016/J.Jvs.2015.02.028 |
0.323 |
|
2016 |
Leaker B, Nicholson G, Petersen C, Panitch A, Brophy C, Lander C. LATE-BREAKING ABSTRACT: Effect of inhaled kinase inhibitor on airway inflammation assessed in induced sputum after challenge with inhaled lipopolysaccharide European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa3542 |
0.536 |
|
2015 |
Evans BC, Hocking KM, Osgood MJ, Voskresensky I, Dmowska J, Kilchrist KV, Brophy CM, Duvall CL. MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia. Science Translational Medicine. 7: 291ra95. PMID 26062847 DOI: 10.1126/Scitranslmed.Aaa4549 |
0.316 |
|
2015 |
Hocking KM, Luo W, Li FD, Komalavilas P, Brophy C, Cheung-Flynn J. Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury. Journal of Vascular Surgery. PMID 25704409 DOI: 10.1016/J.Jvs.2014.12.059 |
0.378 |
|
2013 |
Osgood MJ, Flynn CR, Komalavilas P, Brophy C. Cell-permeant peptide inhibitors of vasospasm and intimal hyperplasia. Vascular. 21: 46-53. PMID 23104826 DOI: 10.1258/Vasc.2011.201203 |
0.478 |
|
2012 |
Muto A, Panitch A, Kim N, Park K, Komalavilas P, Brophy CM, Dardik A. Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. Vascular Pharmacology. 56: 47-55. PMID 22024359 DOI: 10.1016/J.Vph.2011.07.008 |
0.618 |
|
2012 |
Voskresensky IV, Osgood MJ, Hocking KM, Sexton KW, Eagle S, Komalavilas P, Cheung-Flynn J, Brophy C. A Non-Toxic Blue Dye Enhances Smooth Muscle and Endothelial Function of Human Saphenous Vein Bypass Grafts Journal of Surgical Research. 172: 202. DOI: 10.1016/J.Jss.2011.11.267 |
0.343 |
|
2011 |
Hocking KM, Brophy C, Rizvi SZ, Komalavilas P, Eagle S, Leacche M, Balaguer JM, Cheung-Flynn J. Detrimental effects of mechanical stretch on smooth muscle function in saphenous veins. Journal of Vascular Surgery. 53: 454-60. PMID 21146345 DOI: 10.1016/J.Jvs.2010.09.010 |
0.337 |
|
2011 |
Osgood MJ, Hocking KM, Sexton KW, Komalavilas P, Cheung-Flynn J, Leacche M, Eagle S, Brophy C. PS206. “Back-Table” Manipulation of Human Saphenous Vein Significantly Impairs Endothelial and Smooth Muscle Function Journal of Vascular Surgery. 53: 83. DOI: 10.1016/J.Jvs.2011.03.160 |
0.322 |
|
2010 |
Lopes LB, Brophy CM, Flynn CR, Yi Z, Bowen BP, Smoke C, Seal B, Panitch A, Komalavilas P. A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model. Journal of Vascular Surgery. 52: 1596-607. PMID 20864298 DOI: 10.1016/J.Jvs.2010.06.168 |
0.6 |
|
2010 |
Furnish EJ, Brophy CM, Harris VA, Macomson S, Winger J, Head GA, Shaver EG. Treatment with transducible phosphopeptide analogues of the small heat shock-related protein, HSP20, after experimental subarachnoid hemorrhage: prevention and reversal of delayed decreases in cerebral perfusion. Journal of Neurosurgery. 112: 631-9. PMID 20192670 DOI: 10.3171/2009.7.JNS09730 |
0.312 |
|
2010 |
Rizvi S, Komalavilas P, Guzman R, Dattilo J, Brophy C. Expression of the Heat Shock Protein, HSPB1, Is Associated with Impaired Smooth Muscle Relaxation Journal of Surgical Research. 158: 361-362. DOI: 10.1016/J.Jss.2009.11.523 |
0.372 |
|
2009 |
Ba M, Singer CA, Tyagi M, Brophy C, Baker JE, Cremo C, Halayko A, Gerthoffer WT. HSP20 phosphorylation and airway smooth muscle relaxation. Cell Health and Cytoskeleton. 2009: 27-42. PMID 21686039 DOI: 10.2147/CHC.S5783 |
0.334 |
|
2009 |
Ward B, Seal BL, Brophy CM, Panitch A. Design of a bioactive cell-penetrating peptide: when a transduction domain does more than transduce. Journal of Peptide Science : An Official Publication of the European Peptide Society. 15: 668-74. PMID 19691016 DOI: 10.1002/Psc.1168 |
0.591 |
|
2009 |
Lopes LB, Flynn C, Komalavilas P, Panitch A, Brophy CM, Seal BL. Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor. Biochemical and Biophysical Research Communications. 382: 535-9. PMID 19289101 DOI: 10.1016/J.Bbrc.2009.03.056 |
0.601 |
|
2009 |
Lopes LB, Furnish EJ, Komalavilas P, Flynn CR, Ashby P, Hansen A, Ly DP, Yang GP, Longaker MT, Panitch A, Brophy CM. Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts. The Journal of Investigative Dermatology. 129: 590-8. PMID 18787533 DOI: 10.1038/Jid.2008.264 |
0.562 |
|
2008 |
Lopes LB, Furnish E, Komalavilas P, Seal BL, Panitch A, Bentley MV, Brophy CM. Enhanced skin penetration of P20 phosphopeptide using protein transduction domains. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 68: 441-5. PMID 18035527 DOI: 10.1016/J.Ejpb.2007.09.019 |
0.499 |
|
2008 |
Komalavilas P, Penn RB, Flynn CR, Thresher J, Lopes LB, Furnish EJ, Guo M, Pallero MA, Murphy-Ullrich JE, Brophy CM. The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L69-78. PMID 17993590 DOI: 10.1152/Ajplung.00235.2007 |
0.356 |
|
2007 |
Flynn CR, Smoke CC, Furnish E, Komalavilas P, Thresher J, Yi Z, Mandarino LJ, Brophy CM. Phosphorylation and activation of a transducible recombinant form of human HSP20 in Escherichia coli. Protein Expression and Purification. 52: 50-8. PMID 17084643 DOI: 10.1016/J.Pep.2006.08.015 |
0.371 |
|
2007 |
Wheatley G, Komalavilas P, Thresher J, Grow L, Brophy C. 12: Inhibition of phosphorylation of HSP27 decreases vasospasm in human saphenous vein Journal of Surgical Research. 137: 155-156. DOI: 10.1016/J.Jss.2006.12.021 |
0.404 |
|
2005 |
McLemore EC, Tessier DJ, Thresher J, Komalavilas P, Brophy CM. Role of the small heat shock proteins in regulating vascular smooth muscle tone. Journal of the American College of Surgeons. 201: 30-6. PMID 15978441 DOI: 10.1016/j.jamcollsurg.2005.03.017 |
0.358 |
|
2005 |
Lopes LB, Brophy CM, Furnish E, Flynn CR, Sparks O, Komalavilas P, Joshi L, Panitch A, Bentley MV. Comparative study of the skin penetration of protein transduction domains and a conjugated peptide. Pharmaceutical Research. 22: 750-7. PMID 15906170 DOI: 10.1007/S11095-005-2591-X |
0.541 |
|
2005 |
Flynn CR, Brophy CM, Furnish EJ, Komalavilas P, Tessier D, Thresher J, Joshi L. Transduction of phosphorylated heat shock-related protein 20, HSP20, prevents vasospasm of human umbilical artery smooth muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 1836-45. PMID 15829720 DOI: 10.1152/Japplphysiol.01043.2004 |
0.304 |
|
2005 |
Dreiza CM, Brophy CM, Komalavilas P, Furnish EJ, Joshi L, Pallero MA, Murphy-Ullrich JE, von Rechenberg M, Ho YS, Richardson B, Xu N, Zhen Y, Peltier JM, Panitch A. Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 261-3. PMID 15598710 DOI: 10.1096/Fj.04-2911Fje |
0.61 |
|
2004 |
McLemore EC, Tessier DJ, Flynn CR, Furnish EJ, Komalavilas P, Thresher JS, Joshi L, Stone WM, Fowl RJ, Brophy CM. Transducible recombinant small heat shock-related protein, HSP20, inhibits vasospasm and platelet aggregation. Surgery. 136: 573-8. PMID 15349104 DOI: 10.1016/J.Surg.2004.04.024 |
0.326 |
|
2004 |
Tessier DJ, Komalavilas P, Liu B, Kent CK, Thresher JS, Dreiza CM, Panitch A, Joshi L, Furnish E, Stone W, Fowl R, Brophy CM. Transduction of peptide analogs of the small heat shock-related protein HSP20 inhibits intimal hyperplasia. Journal of Vascular Surgery. 40: 106-14. PMID 15218470 DOI: 10.1016/J.Jvs.2004.03.028 |
0.576 |
|
2004 |
Tessier DJ, Komalavilas P, McLemore E, Thresher J, Brophy CM. Sildenafil-induced vasorelaxation is associated with increases in the phosphorylation of the heat shock-related protein 20 (HSP20). The Journal of Surgical Research. 118: 21-5. PMID 15093712 DOI: 10.1016/j.jss.2004.01.001 |
0.315 |
|
2004 |
McLemore EC, Tessier D, Komalavilas P, Thresher J, Brophy C. The yin and yang of vascular smooth muscle tone Journal of the American College of Surgeons. 199: 106-107. DOI: 10.1016/J.Jamcollsurg.2004.05.241 |
0.415 |
|
2003 |
Tessier DJ, Komalavilas P, Panitch A, Joshi L, Brophy CM. The small heat shock protein (HSP) 20 is dynamically associated with the actin cross-linking protein actinin. The Journal of Surgical Research. 111: 152-7. PMID 12842460 DOI: 10.1016/S0022-4804(03)00113-6 |
0.559 |
|
2003 |
Flynn CR, Komalavilas P, Tessier D, Thresher J, Niederkofler EE, Dreiza CM, Nelson RW, Panitch A, Joshi L, Brophy CM. Transduction of biologically active motifs of the small heat shock-related protein HSP20 leads to relaxation of vascular smooth muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1358-60. PMID 12738803 DOI: 10.1096/Fj.02-1028Fje |
0.617 |
|
2003 |
Woodrum D, Pipkin W, Tessier D, Komalavilas P, Brophy CM. Phosphorylation of the heat shock-related protein, HSP20, mediates cyclic nucleotide-dependent relaxation. Journal of Vascular Surgery. 37: 874-81. PMID 12663991 DOI: 10.1067/mva.2003.153 |
0.358 |
|
2003 |
Pipkin W, Johnson JA, Creazzo TL, Burch J, Komalavilas P, Brophy C. Localization, macromolecular associations, and function of the small heat shock-related protein HSP20 in rat heart. Circulation. 107: 469-76. PMID 12551873 DOI: 10.1161/01.Cir.0000044386.27444.5A |
0.435 |
|
2002 |
Macomson SD, Brophy CM, Miller W, Harris VA, Shaver EG. Heat shock protein expression in cerebral vessels after subarachnoid hemorrhage. Neurosurgery. 51: 204-10; discussion 2. PMID 12182419 DOI: 10.1097/00006123-200207000-00029 |
0.304 |
|
2002 |
Brophy CM, Woodrum DA, Pollock J, Dickinson M, Komalavilas P, Cornwell TL, Lincoln TM. cGMP-dependent protein kinase expression restores contractile function in cultured vascular smooth muscle cells. Journal of Vascular Research. 39: 95-103. PMID 12011581 DOI: 10.1159/000057758 |
0.308 |
|
2002 |
Brophy CM. Stress and vascular disease at the cellular and molecular levels. World Journal of Surgery. 26: 779-82. PMID 11948370 DOI: 10.1007/s00268-002-4052-6 |
0.317 |
|
2002 |
Brophy C, Woodrum D. Phosphorylation of HSP20 on serine 157. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 890-1. PMID 11838439 DOI: 10.1152/Japplphysiol.00879.2001 |
0.355 |
|
2000 |
Fuchs LC, Giulumian AD, Knoepp L, Pipkin WL, Dickinson M, Hayles C, Brophy C. Stress causes decrease in vascular relaxation linked with altered phosphorylation of heat shock proteins American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 279. PMID 10938237 DOI: 10.1152/Ajpregu.2000.279.2.R492 |
0.43 |
|
2000 |
Jerius H, Bagwell CA, Beall A, Karolyi D, Brophy C. Vascular smooth muscle mechanics in isolated perfused segments of carotid arteries. Surgery. 127: 148-154. PMID 10686979 DOI: 10.1067/Msy.2000.101153 |
0.318 |
|
1999 |
Woodrum DA, Brophy CM, Wingard CJ, Beall A, Rasmussen H. Phosphorylation events associated with cyclic nucleotidedependent inhibition of smooth muscle contraction. American Journal of Physiology. Heart and Circulatory Physiology. 277: H931-H939. PMID 29592086 DOI: 10.1152/ajpheart.1999.277.3.H931 |
0.31 |
|
1999 |
Knoepp L, Mondy JS, Brophy C. Phosphorylation Of Hsp27 Leads To Alterations In Cyclic Nucleotide Dependent Relaxation Shock. 11: 61. DOI: 10.1097/00024382-199906001-00212 |
0.368 |
|
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