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Shannon M. Reilly, Ph.D. - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
Biochemistry, Public Health, Aging
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ma L, Gilani A, Rubio-Navarro A, Cortada E, Li A, Reilly SM, Tang L, Lo JC. Adipsin and Adipocyte-derived C3aR1 Regulate Thermogenic Fat in a Sex-dependent Fashion. Jci Insight. PMID 38713526 DOI: 10.1172/jci.insight.178925  0.34
2024 Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne TE, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu RT, Downes M, Evans RM, Rydén M, ... ... Reilly SM, et al. Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation. Nature Metabolism. PMID 38286821 DOI: 10.1038/s42255-024-00978-0  0.408
2023 Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne T, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu R, Downes M, Evans R, Ryden M, ... ... Reilly S, et al. Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes. Research Square. PMID 37398165 DOI: 10.21203/rs.3.rs-2923510/v1  0.415
2021 Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, et al. Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes. Nature. PMID 34707293 DOI: 10.1038/s41586-021-04019-8  0.42
2021 Reilly SM, Abu-Odeh M, Ameka M, DeLuca JH, Naber MC, Dadpey B, Ebadat N, Gomez AV, Peng X, Poirier B, Walk E, Potthoff MJ, Saltiel AR. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. The Journal of Clinical Investigation. PMID 33822771 DOI: 10.1172/JCI145546  0.396
2020 Reilly SM, Hung CW, Ahmadian M, Zhao P, Keinan O, Gomez AV, DeLuca JH, Dadpey B, Lu D, Zaid J, Poirier B, Peng X, Yu RT, Downes M, Liddle C, et al. Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nature Metabolism. 2: 620-634. PMID 32694788 DOI: 10.1038/s42255-020-0217-6  0.387
2019 Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, et al. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289229 DOI: 10.1073/Pnas.1904360116  0.424
2019 GOMEZ AV, REILLY S, ODEH MA, WALK E, SALTIEL A. 2043-P: The Biphasic Antiobesogenic Effects of Amlexanox Diabetes. 68: 2043-P. DOI: 10.2337/Db19-2043-P  0.337
2018 Beyett TS, Gan X, Reilly SM, Gomez AV, Chang L, Tesmer JJG, Saltiel AR, Showalter HD. Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity. Bioorganic & Medicinal Chemistry. PMID 30270002 DOI: 10.1016/J.Bmc.2018.09.020  0.338
2018 Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, et al. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915037 DOI: 10.1073/Pnas.1801050115  0.409
2018 Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, et al. ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell Reports. 22: 2849-2859. PMID 29539415 DOI: 10.1016/J.Celrep.2018.02.061  0.414
2018 Zhao P, Wong KI, Sun X, Reilly SM, Uhm M, Liao Z, Skorobogatko Y, Saltiel AR. TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 172: 731-743.e12. PMID 29425491 DOI: 10.1016/J.Cell.2018.01.007  0.467
2018 Beyett TS, Gan X, Reilly SM, Chang L, Gomez AV, Saltiel AR, Showalter HD, Tesmer JJG. Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition. Molecular Pharmacology. 94: 1210-1219. DOI: 10.2210/Pdb6Boe/Pdb  0.362
2017 Cho CS, Park HW, Ho A, Semple IA, Kim B, Jang I, Park H, Reilly S, Saltiel AR, Lee JH. Lipotoxicity induces hepatic protein inclusions through TBK1-mediated p62/SQSTM1 phosphorylation. Hepatology (Baltimore, Md.). PMID 29251796 DOI: 10.1002/Hep.29742  0.317
2017 Reilly SM, Saltiel AR. Adapting to obesity with adipose tissue inflammation. Nature Reviews. Endocrinology. PMID 28799554 DOI: 10.1038/Nrendo.2017.90  0.427
2017 Oral EA, Reilly SM, Gomez AV, Meral R, Butz L, Ajluni N, Chenevert TL, Korytnaya E, Neidert AH, Hench R, Rus D, Horowitz JF, Poirier B, Zhao P, Lehmann K, et al. Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes. Cell Metabolism. 26: 157-170.e7. PMID 28683283 DOI: 10.1016/J.Cmet.2017.06.006  0.436
2015 Reilly SM, Saltiel AR. A Futile Approach to Fighting Obesity? Cell. 163: 539-40. PMID 26496598 DOI: 10.1016/J.Cell.2015.10.006  0.366
2015 Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, et al. A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nature Communications. 6: 6047. PMID 25581158 DOI: 10.1038/Ncomms7047  0.479
2015 Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760  0.508
2014 Reilly SM, Saltiel AR. Obesity: A complex role for adipose tissue macrophages Nature Reviews Endocrinology. 10: 193-194. PMID 24492182 DOI: 10.1038/Nrendo.2014.12  0.467
2013 Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR. Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1. Elife. 2: e01119. PMID 24368730 DOI: 10.7554/Elife.01119  0.37
2013 Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, et al. An inhibitor of the protein kinases TBK1 and IKK-É› improves obesity-related metabolic dysfunctions in mice. Nature Medicine. 19: 313-21. PMID 23396211 DOI: 10.1038/Nm.3082  0.413
2013 Liu S, Reilly SM, Lee CH. Transcriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor. Antioxidants & Redox Signaling. 19: 299-309. PMID 22703297 DOI: 10.1089/Ars.2011.4413  0.644
2013 Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang S, Chang L, Saltiel AR. Author response: Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1 Elife. DOI: 10.7554/Elife.01119.013  0.331
2011 Liu S, Hatano B, Zhao M, Yen CC, Kang K, Reilly SM, Gangl MR, Gorgun C, Balschi JA, Ntambi JM, Lee CH. Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. The Journal of Biological Chemistry. 286: 1237-47. PMID 21059653 DOI: 10.1074/Jbc.M110.138115  0.647
2010 Reilly SM, Bhargava P, Liu S, Gangl MR, Gorgun C, Nofsinger RR, Evans RM, Qi L, Hu FB, Lee CH. Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. Cell Metabolism. 12: 643-53. PMID 21109196 DOI: 10.1016/J.Cmet.2010.11.007  0.612
2008 Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, Lee CH. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metabolism. 7: 485-95. PMID 18522830 DOI: 10.1016/J.Cmet.2008.04.002  0.608
2008 Reilly SM, Lee CH. PPAR delta as a therapeutic target in metabolic disease. Febs Letters. 582: 26-31. PMID 18036566 DOI: 10.1016/J.Febslet.2007.11.040  0.662
2008 Reilly SM, Lee CH. Nuclear receptors in the control of lipid metabolism Atherosclerosis and Oxidant Stress: a New Perspective. 96-122. DOI: 10.1007/978-0-387-72347-1_6  0.657
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