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Titus Boggon - Publications

Affiliations: 
Pharmacology Yale University, New Haven, CT 
Area:
Biochemistry, Pharmacology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882  0.538
2016 Jin L, Li D, Alesi G, Fan J, Kang H, Zhou L, Boggon T, Jin P, Egnatchik R, DeBerardinis R, Magliocca K, He C, Arellano M, Khoury H, Shin D, et al. Abstract A17: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A17  0.307
2015 Ha BH, Simpson MA, Koleske AJ, Boggon TJ. Structure of the ABL2/ARG kinase in complex with dasatinib. Acta Crystallographica. Section F, Structural Biology Communications. 71: 443-8. PMID 25849507 DOI: 10.1107/S2053230X15004793  0.301
2015 Reshetnyak AV, Opatowsky Y, Boggon TJ, Folta-Stogniew E, Tome F, Lax I, Schlessinger J. The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer. Molecular Cell. 57: 191-201. PMID 25544564 DOI: 10.1016/J.Molcel.2014.11.021  0.31
2015 Tarlock K, Hansen ME, Hylkema T, Ries R, Farrar JE, Auvil JG, Gerhard DS, Smith MA, Davidsen TM, Gesuwan P, Hermida LC, Marra MA, Mungall AJ, Mungall K, Ma Y, ... ... Boggon T, et al. Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative Blood. 126: 87-87. DOI: 10.1182/Blood.V126.23.87.87  0.342
2014 Shan C, Elf SE, Gu T, Khoury HJ, Boggon T, Kang S, Chen J. Abstract 961: 6-phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumor growth by inhibiting LKB1-AMPK signaling Cancer Research. 74: 961-961. DOI: 10.1158/1538-7445.Am2014-961  0.32
2014 Fan J, Gu T, Boggon T, Kang S, Chen J. Abstract 3362: Tyr-phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate pyruvate dehydrogenase complex and promote the Warburg effect Cancer Research. 74: 3362-3362. DOI: 10.1158/1538-7445.Am2014-3362  0.356
2013 Hitosugi T, Zhou L, Arellano M, Khoury H, Boggon T, Kang S, He C, Chen J. Abstract 4612: Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Research. 73: 4612-4612. DOI: 10.1158/1538-7445.Am2013-4612  0.326
2012 Hitosugi T, Zhou L, Fan J, Arellano M, Khoury HJ, Lee BH, Boggon T, Kang S, He C, Chen J. Phosphoglycerate Mutase 1 Promotes Leukemia Metabolism by Coordinating Glycolysis and Biosynthesis, and Represnts a Therapuetic Target in Leukemia Treatment Blood. 120: 860-860. DOI: 10.1182/Blood.V120.21.860.860  0.325
2011 Fan J, Hitosugi T, Chung T, Wang X, Gu T, Roesel JL, Chen Z(, Boggon T, Khuri FR, Kang S, Chen J. Abstract 2798: Tyrosine phosphorylation of LDH-A is important for cancer cell redox homeostasis and tumor growth Cancer Research. 71: 2798-2798. DOI: 10.1158/1538-7445.Am2011-2798  0.373
2011 Chung T, Hitosugi T, Fan J, Wang X, Gu T, Roesel JL, Boggon T, Chen Z(, Khuri FR, Kang S, Chen J. Abstract 1257: Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism Cancer Research. 71: 1257-1257. DOI: 10.1158/1538-7445.Am2011-1257  0.373
2010 Hitosugi T, Kang S, Vander Heiden M, Chung T, Elf S, Lythgoe K, Dong S, Lonial S, Wang X, Chen G, Xie J, Gu T, Polakiewicz R, Roesel JL, Boggon T, et al. Leukemogenic Tyrosine Kinases Inhibit PKM2 to Promote the Warburg Effect and Tumor Growth Blood. 116: 3142-3142. DOI: 10.1182/Blood.V116.21.3142.3142  0.4
2010 Hitosugi T, Kang S, Heiden MGV, Chung T, Lonial S, Wang X, Chen GZ, Xie J, Gu T, Polakiewicz RD, Roesel JL, Boggon T, Khuri F, Gilliland DG, Cantley LC, et al. Abstract 34: Oncogenic tyrosine kinases phosphorylate and inhibit PKM2 to provide a metabolic advantage to tumor growth Cancer Research. 70: 34-34. DOI: 10.1158/1538-7445.Am10-34  0.401
2007 Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 11: 217-27. PMID 17349580 DOI: 10.1016/J.Ccr.2006.12.017  0.556
2005 Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 7: 387-97. PMID 15837627 DOI: 10.1016/J.Ccr.2005.03.023  0.51
2005 Boggon TJ, Li Y, Manley PW, Eck MJ. Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog. Blood. 106: 996-1002. PMID 15831699 DOI: 10.1182/Blood-2005-02-0707  0.574
2005 Kobayashi S, Boggon TJ, Dayaram T, Jänne PA, Kocher O, Meyerson M, Johnson BE, Eck MJ, Tenen DG, Halmos B. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine. 352: 786-92. PMID 15728811 DOI: 10.1056/Nejmoa044238  0.519
2005 Snell EH, Helliwell JR, Boggon TJ, Lautenschlager P, Potthast L. Lysozyme crystal growth kinetics monitored using a Mach-Zehnder interferometer. Acta Crystallographica. Section D, Biological Crystallography. 52: 529-33. PMID 15299675 DOI: 10.1107/S090744499600042X  0.457
2005 Boggon TJ. Jak3 Kinase Domain Crystal Structures and Implications for Jak-Specific Drug Design. Blood. 106: 69-69. DOI: 10.1182/BLOOD.V106.11.69.69  0.355
2004 Boggon TJ, Eck MJ. Structure and regulation of Src family kinases. Oncogene. 23: 7918-27. PMID 15489910 DOI: 10.1038/Sj.Onc.1208081  0.539
2004 Jiang J, Paez JG, Lee JC, Bo R, Stone RM, DeAngelo DJ, Galinsky I, Wolpin BM, Jonasova A, Herman P, Fox EA, Boggon TJ, Eck MJ, Weisberg E, Griffin JD, et al. Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML. Blood. 104: 1855-8. PMID 15178581 DOI: 10.1182/Blood-2004-02-0712  0.543
2004 Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, Herman P, Kaye FJ, Lindeman N, Boggon TJ, Naoki K, Sasaki H, Fujii Y, Eck MJ, Sellers WR, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science (New York, N.Y.). 304: 1497-500. PMID 15118125 DOI: 10.1126/Science.1099314  0.525
2004 Boggon TJ, Li Y, Eck MJ. Structural Analysis of Janus Kinases. Blood. 104: 3863-3863. DOI: 10.1182/Blood.V104.11.3863.3863  0.53
2003 Habash J, Boggon TJ, Raftery J, Chayen NE, Zagalsky PF, Helliwell JR. Apocrustacyanin C(1) crystals grown in space and on earth using vapour-diffusion geometry: protein structure refinements and electron-density map comparisons. Acta Crystallographica. Section D, Biological Crystallography. 59: 1117-23. PMID 12832753  0.462
2002 Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, Shapiro L. C-cadherin ectodomain structure and implications for cell adhesion mechanisms. Science (New York, N.Y.). 296: 1308-13. PMID 11964443 DOI: 10.1126/Science.1071559  0.47
2001 Santagata S, Boggon TJ, Baird CL, Gomez CA, Zhao J, Shan WS, Myszka DG, Shapiro L. G-protein signaling through tubby proteins. Science (New York, N.Y.). 292: 2041-50. PMID 11375483 DOI: 10.1126/Science.1061233  0.473
2000 Boggon TJ, Helliwell JR, Judge RA, Olczak A, Siddons DP, Snell EH, Stojanoff V. Synchrotron X-ray reciprocal-space mapping, topography and diffraction resolution studies of macromolecular crystal quality. Acta Crystallographica. Section D, Biological Crystallography. 56: 868-80. PMID 10930833 DOI: 10.1107/S0907444900005837  0.433
2000 Boggon TJ, Shapiro L. Screening for phasing atoms in protein crystallography Structure. 8. PMID 10903954 DOI: 10.1016/S0969-2126(00)00168-4  0.398
2000 Boggon TJ, Shan WS, Santagata S, Myers SC, Shapiro L. Implication of Tubby Proteins as Transcription Factors by Structure-Based Functional Analysis Acta Crystallographica Section A. 56: 263-263. DOI: 10.1107/S0108767300025642  0.446
1999 Boggon TJ, Shan WS, Santagata S, Myers SC, Shapiro L. Implication of tubby proteins as transcription factors by structure-based functional analysis. Science (New York, N.Y.). 286: 2119-25. PMID 10591637 DOI: 10.1126/Science.286.5447.2119  0.491
1999 Chayen NE, Boggon TJ, Raftery J, Helliwell JR, Zagalsky PF. Purification, crystallization and initial X-ray analysis of the C1 subunit of the astaxanthin protein, V600, of the chondrophore Velella velella. Acta Crystallographica. Section D, Biological Crystallography. 55: 266-8. PMID 10089420 DOI: 10.1107/S0907444998006908  0.445
1999 Dong J, Boggon TJ, Chayen NE, Raftery J, Bi RC, Helliwell JR. Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution. Acta Crystallographica. Section D, Biological Crystallography. 55: 745-52. PMID 10089304 DOI: 10.1107/S0907444998016047  0.473
1998 Boggon TJ, Chayen NE, Snell EH, Dong J, Lautenschlager P, Potthast L, Siddons DP, Stojanoff V, Gordon E, Thompson AW, Zagalsky PF, Bi R, Helliwell JR. Protein crystal movements and fluid flows during microgravity growth Philosophical Transactions of the Royal Society of London. Series a: Mathematical, Physical and Engineering Sciences. 356: 1045-1061. DOI: 10.1098/rsta.1998.0208  0.422
1997 Snell EH, Cassetta A, Helliwell JR, Boggon TJ, Chayen NE, Weckert E, Hölzer K, Schroer K, Gordon EJ, Zagalsky PF. Partial improvement of crystal quality for microgravity-grown apocrustacyanin C1. Acta Crystallographica. Section D, Biological Crystallography. 53: 231-9. PMID 15299925 DOI: 10.1107/S0907444996013996  0.451
1997 Snell EH, Boggon TJ, Helliwell JR, Moskowitz ME, Nadarajah A. CCD video observation of microgravity crystallization of lysozyme and correlation with accelerometer data. Acta Crystallographica. Section D, Biological Crystallography. 53: 747-55. PMID 11540584 DOI: 10.1107/S0907444997007968  0.461
1996 Chayen NE, Boggon TJ, Cassetta A, Deacon A, Gleichmann T, Habash J, Harrop SJ, Helliwell JR, Nieh YP, Peterson MR, Raftery J, Snell EH, Hädener A, Niemann AC, Siddons DP, et al. Trends and challenges in experimental macromolecular crystallography. Quarterly Reviews of Biophysics. 29: 227-78. PMID 8968112 DOI: 10.1017/S0033583500005837  0.359
1996 Snell EH, Helliwell JR, Cassetta A, Boggon TJ, Chayen NE, Weckert E, Holzer K, Schroer K, Stojanoff V, Siddons DP. Protein crystal perfection and the crystal growth process Acta Crystallographica Section a Foundations of Crystallography. 52: C517-C517. DOI: 10.1107/S0108767396078920  0.458
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