Year |
Citation |
Score |
2013 |
Huang YC, Hung WC, Chen WT, Yu HS, Chai CY. Expression of WWOX and FHIT is downregulated by exposure to arsenite in human uroepithelial cells. Toxicology Letters. 220: 118-25. PMID 23618899 DOI: 10.1016/j.toxlet.2013.04.007 |
0.367 |
|
2012 |
Liu XP, Huang YC, Hung WC, Chen WT, Yu HS, Chai CY. Sodium arsenite-induced abnormalities in expressions of Caveolin-1, eNOS, IKKβ, and COX-2 in SV-40 immortalized human uroepithelial cells and in urothelial carcinomas. Toxicology in Vitro : An International Journal Published in Association With Bibra. 26: 1098-105. PMID 22824620 DOI: 10.1016/j.tiv.2012.07.003 |
0.389 |
|
2011 |
Bretones G, Acosta JC, Caraballo JM, Ferrándiz N, Gómez-Casares MT, Albajar M, Blanco R, Ruiz P, Hung WC, Albero MP, Perez-Roger I, León J. SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells. The Journal of Biological Chemistry. 286: 9815-25. PMID 21245140 DOI: 10.1074/jbc.M110.165977 |
0.337 |
|
2010 |
Huang YC, Hung WC, Chen WT, Yu HS, Chai CY. Effects of DNMT and MEK inhibitors on the expression of RECK, MMP-9, -2, uPA and VEGF in response to arsenite stimulation in human uroepithelial cells. Toxicology Letters. 201: 62-71. PMID 21167264 DOI: 10.1016/j.toxlet.2010.12.006 |
0.312 |
|
2010 |
Huang YC, Hung WC, Chen WT, Jiang WH, Yu HS, Chai CY. Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16. Toxicology Letters. 200: 59-66. PMID 21040761 DOI: 10.1016/j.toxlet.2010.10.015 |
0.338 |
|
2009 |
Liu XY, Ho WY, Hung WJ, Shau MD. The characteristics and transfection efficiency of cationic poly (ester-co-urethane) - short chain PEI conjugates self-assembled with DNA. Biomaterials. 30: 6665-73. PMID 19775745 DOI: 10.1016/j.biomaterials.2009.08.052 |
0.333 |
|
2008 |
Pan MR, Chang HC, Chuang LY, Hung WC. The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells. Experimental Biology and Medicine (Maywood, N.J.). 233: 456-62. PMID 18367635 DOI: 10.3181/0709-RM-257 |
0.344 |
|
2008 |
Hsu MC, Chai CY, Hou MF, Chang HC, Chen WT, Hung WC. Jab1 is overexpressed in human breast cancer and is a downstream target for HER-2/neu. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 609-16. PMID 18246048 DOI: 10.1038/modpathol.2008.23 |
0.325 |
|
2008 |
Hsu MC, Chang HC, Hung WC. HER-2/neu transcriptionally activates Jab1 expression via the AKT/beta-catenin pathway in breast cancer cells. Endocrine-Related Cancer. 14: 655-67. PMID 17914096 DOI: 10.1677/ERC-07-0077 |
0.322 |
|
2007 |
Chai CY, Huang YC, Hung WC, Kang WY, Chen WT. Arsenic salt-induced DNA damage and expression of mutant p53 and COX-2 proteins in SV-40 immortalized human uroepithelial cells. Mutagenesis. 22: 403-8. PMID 17906315 DOI: 10.1093/MUTAGE/GEM035 |
0.375 |
|
2007 |
Huang YC, Hung WC, Kang WY, Chen WT, Chai CY. Expression of STAT3 and Bcl-6 oncoprotein in sodium arsenite-treated SV-40 immortalized human uroepithelial cells. Toxicology Letters. 173: 57-65. PMID 17689208 DOI: 10.1016/J.TOXLET.2007.06.009 |
0.304 |
|
2007 |
Chai CY, Huang YC, Hung WC, Kang WY, Chen WT. Arsenic salts induced autophagic cell death and hypermethylation of DAPK promoter in SV-40 immortalized human uroepithelial cells. Toxicology Letters. 173: 48-56. PMID 17683884 DOI: 10.1016/J.TOXLET.2007.06.006 |
0.304 |
|
2007 |
Chang HC, Chang FR, Wang YC, Pan MR, Hung WC, Wu YC. A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression. Molecular Cancer Therapeutics. 6: 1572-8. PMID 17513606 DOI: 10.1158/1535-7163.MCT-06-0812 |
0.336 |
|
2007 |
Cho CY, Wang JH, Chang HC, Chang CK, Hung WC. Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells. Journal of Cellular Physiology. 213: 65-9. PMID 17443689 DOI: 10.1002/jcp.21089 |
0.331 |
|
2004 |
Liu LT, Peng JP, Chang HC, Hung WC. RECK is a target of Epstein-Barr virus latent membrane protein 1. Oncogene. 22: 8263-70. PMID 14614450 DOI: 10.1038/sj.onc.1207157 |
0.302 |
|
2004 |
Peng JP, Liu LT, Chang HC, Hung WC. Enhancement of chemotherapeutic drug-induced apoptosis by a cyclooxygenase-2 inhibitor in hypopharyngeal carcinoma cells. Cancer Letters. 201: 157-63. PMID 14607329 DOI: 10.1016/S0304-3835(03)00470-1 |
0.334 |
|
1999 |
Lee TH, Chuang LY, Hung WC. Tamoxifen induces p21WAF1 and p27KIP1 expression in estrogen receptor-negative lung cancer cells. Oncogene. 18: 4269-74. PMID 10435640 DOI: 10.1038/sj.onc.1202755 |
0.314 |
|
Low-probability matches (unlikely to be authored by this person) |
2009 |
Huang YC, Hung WC, Chen WT, Yu HS, Chai CY. Sodium arsenite-induced DAPK promoter hypermethylation and autophagy via ERK1/2 phosphorylation in human uroepithelial cells. Chemico-Biological Interactions. 181: 254-62. PMID 19577553 DOI: 10.1016/j.cbi.2009.06.020 |
0.293 |
|
2011 |
Yang KT, Wang MC, Chen JY, Hsu MC, Hung WC. Bcr-Abl oncogene stimulates Jab1 expression via cooperative interaction of β-catenin and STAT1 in chronic myeloid leukemia cells. Journal of Cellular Physiology. 226: 2849-56. PMID 21935931 DOI: 10.1002/jcp.22633 |
0.293 |
|
2008 |
Pan MR, Hou MF, Chang HC, Hung WC. Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells. The Journal of Biological Chemistry. 283: 11155-63. PMID 18319253 DOI: 10.1074/jbc.M710038200 |
0.292 |
|
2016 |
Chen JY, Li CF, Chu PY, Lai YS, Chen CH, Jiang SS, Hou MF, Hung WC. Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1. Oncotarget. PMID 27029061 DOI: 10.18632/oncotarget.8381 |
0.292 |
|
2017 |
Hou MF, Luo CW, Chang TM, Hung WC, Chen TY, Tsai YL, Chai CY, Pan MR. The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer. Experimental Cell Research. PMID 28842166 DOI: 10.1016/j.yexcr.2017.08.029 |
0.29 |
|
2013 |
Chang TM, Hung WC. The homeobox transcription factor Prox1 inhibits proliferation of hepatocellular carcinoma cells by inducing p53-dependent senescence-like phenotype. Cancer Biology & Therapy. 14: 222-9. PMID 23291986 DOI: 10.4161/cbt.23293 |
0.29 |
|
2013 |
Chuang CW, Pan MR, Hou MF, Hung WC. Cyclooxygenase-2 up-regulates CCR7 expression via AKT-mediated phosphorylation and activation of Sp1 in breast cancer cells. Journal of Cellular Physiology. 228: 341-8. PMID 22718198 DOI: 10.1002/jcp.24136 |
0.287 |
|
2009 |
Pan MR, Chang TM, Chang HC, Su JL, Wang HW, Hung WC. Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells. Journal of Cell Science. 122: 3358-64. PMID 19706680 DOI: 10.1242/jcs.050005 |
0.285 |
|
2002 |
Huang YC, Chuang LY, Hung WC. Mechanisms underlying nonsteroidal anti-inflammatory drug-induced p27(Kip1) expression. Molecular Pharmacology. 62: 1515-21. PMID 12435820 DOI: 10.1124/MOL.62.6.1515 |
0.285 |
|
2011 |
Hong KJ, Hsu MC, Hou MF, Hung WC. The tumor suppressor RECK interferes with HER-2/Neu dimerization and attenuates its oncogenic signaling. Febs Letters. 585: 591-5. PMID 21255571 DOI: 10.1016/j.febslet.2011.01.021 |
0.284 |
|
2003 |
Lee TH, Chang HC, Chuang LY, Hung WC. Involvement of PKA and Sp1 in the induction of p27(Kip1) by tamoxifen. Biochemical Pharmacology. 66: 371-7. PMID 12907235 DOI: 10.1016/S0006-2952(03)00258-2 |
0.28 |
|
2008 |
Chou WW, Guh JY, Tsai JF, Hwang CC, Chen HC, Huang JS, Yang YL, Hung WC, Chuang LY. Arecoline-induced growth arrest and p21WAF1 expression are dependent on p53 in rat hepatocytes Toxicology. 243: 1-10. PMID 17997002 DOI: 10.1016/j.tox.2007.09.003 |
0.275 |
|
2006 |
Wang CH, Chang HC, Hung WC. p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription. Journal of Cellular Physiology. 208: 246-52. PMID 16575904 DOI: 10.1002/jcp.20660 |
0.275 |
|
2015 |
Huang HL, Chiang CH, Hung WC, Hou MF. Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer. Oncotarget. 6: 995-1007. PMID 25557171 DOI: 10.18632/ONCOTARGET.2739 |
0.27 |
|
2005 |
Hsu MC, Chang HC, Hung WC. HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. The Journal of Biological Chemistry. 281: 4718-25. PMID 16377629 DOI: 10.1074/jbc.M510937200 |
0.27 |
|
2009 |
Pan MR, Chang HC, Wu YC, Huang CC, Hung WC. Tubocapsanolide A inhibits transforming growth factor-beta-activating kinase 1 to suppress NF-kappaB-induced CCR7. The Journal of Biological Chemistry. 284: 2746-54. PMID 19049961 DOI: 10.1074/jbc.M806223200 |
0.269 |
|
2002 |
Peng JP, Su CY, Chang HC, Chai CY, Hung WC. Overexpression of cyclo-oxygenase 2 in squamous cell carcinoma of the hypopharynx. Human Pathology. 33: 100-4. PMID 11823979 |
0.268 |
|
2000 |
Lee TH, Chuang LY, Hung WC. Induction of p21WAF1 expression via Sp1-binding sites by tamoxifen in estrogen receptor-negative lung cancer cells. Oncogene. 19: 3766-73. PMID 10949931 DOI: 10.1038/sj.onc.1203715 |
0.267 |
|
2008 |
Chang SH, Chang HC, Hung WC. Transcriptional repression of tissue inhibitor of metalloproteinase-3 by Epstein-Barr virus latent membrane protein 1 enhances invasiveness of nasopharyngeal carcinoma cells. Oral Oncology. 44: 891-7. PMID 18289921 DOI: 10.1016/j.oraloncology.2007.11.005 |
0.263 |
|
2017 |
Chang TM, Shan YS, Chu PY, Jiang SS, Hung WC, Chen YL, Tu HC, Lin HY, Tsai HJ, Chen LT. The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors. Oncotarget. 8: 98068-98083. PMID 29228674 DOI: 10.18632/oncotarget.20956 |
0.261 |
|
2019 |
Chen HC, Tseng YK, Shu CW, Fu TY, Liou HH, Huang CH, Chen CC, Wang JS, Wu PC, Ger LP, Hung WC, Liu PF. Prognostic role of RECK in pathological outcome-dependent buccal mucosa squamous cell carcinoma. Oral Diseases. PMID 31618798 DOI: 10.1111/odi.13214 |
0.258 |
|
2014 |
Su ML, Chang TM, Chiang CH, Chang HC, Hou MF, Li WS, Hung WC. Inhibition of chemokine (C-C motif) receptor 7 sialylation suppresses CCL19-stimulated proliferation, invasion and anti-anoikis. Plos One. 9: e98823. PMID 24915301 DOI: 10.1371/Journal.Pone.0098823 |
0.255 |
|
2007 |
Chang HC, Cho CY, Hung WC. Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer. Cancer Science. 98: 169-73. PMID 17233834 DOI: 10.1111/j.1349-7006.2006.00367.x |
0.254 |
|
2019 |
Chen JY, Lai YS, Chu PY, Chan SH, Wang LH, Hung WC. Cancer-Derived VEGF-C Increases Chemokine Production in Lymphatic Endothelial Cells to Promote CXCR2-Dependent Cancer Invasion and MDSC Recruitment. Cancers. 11. PMID 31390756 DOI: 10.3390/cancers11081120 |
0.25 |
|
2013 |
Huang HL, Hsu HP, Shieh SC, Chang YS, Chen WC, Cho CY, Teng CF, Su IJ, Hung WC, Lai MD. Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide. Molecular Cancer Therapeutics. 12: 2505-16. PMID 23979921 DOI: 10.1158/1535-7163.MCT-12-0863 |
0.249 |
|
2014 |
Hong KJ, Wu DC, Cheng KH, Chen LT, Hung WC. RECK inhibits stemness gene expression and tumorigenicity of gastric cancer cells by suppressing ADAM-mediated Notch1 activation. Journal of Cellular Physiology. 229: 191-201. PMID 23881612 DOI: 10.1002/jcp.24434 |
0.249 |
|
2007 |
Huang YC, Hung WC, Kang WY, Chen WT, Chai CY. p-Phenylenediamine induced DNA damage in SV-40 immortalized human uroepithelial cells and expression of mutant p53 and COX-2 proteins. Toxicology Letters. 170: 116-23. PMID 17403587 DOI: 10.1016/J.TOXLET.2007.02.011 |
0.249 |
|
2006 |
Tsai YS, Chang HC, Chuang LY, Hung WC. RNA silencing of Cks1 induced G2/M arrest and apoptosis in human lung cancer cells. Iubmb Life. 57: 583-9. PMID 16118116 DOI: 10.1080/15216540500215531 |
0.248 |
|
2006 |
Peng JP, Chang HC, Hwang CF, Hung WC. Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with lymph node metastasis. Oral Oncology. 41: 903-8. PMID 16054423 DOI: 10.1016/J.ORALONCOLOGY.2005.05.003 |
0.248 |
|
2012 |
Chang TM, Hung WC. Transcriptional repression of TWIST1 gene by Prospero-related homeobox 1 inhibits invasiveness of hepatocellular carcinoma cells. Febs Letters. 586: 3746-52. PMID 22982861 DOI: 10.1016/j.febslet.2012.08.034 |
0.243 |
|
2004 |
Hung WC, Chang HC. Methanolic extract of adlay seed suppresses COX-2 expression of human lung cancer cells via inhibition of gene transcription. Journal of Agricultural and Food Chemistry. 51: 7333-7. PMID 14640580 DOI: 10.1021/JF0340512 |
0.243 |
|
2010 |
Chiang CH, Wang CH, Chang HC, More SV, Li WS, Hung WC. A novel sialyltransferase inhibitor AL10 suppresses invasion and metastasis of lung cancer cells by inhibiting integrin-mediated signaling. Journal of Cellular Physiology. 223: 492-9. PMID 20112294 DOI: 10.1002/Jcp.22068 |
0.242 |
|
2002 |
Liu LT, Chang HC, Chiang LC, Hung WC. Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells. Oncogene. 21: 8347-50. PMID 12447698 DOI: 10.1038/sj.onc.1206017 |
0.24 |
|
2009 |
Hung YH, Hung WC. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway. Chemico-Biological Interactions. 179: 154-9. PMID 19027725 DOI: 10.1016/j.cbi.2008.10.042 |
0.239 |
|
2011 |
Wang CH, Shih WC, Chang HC, Kuo YY, Hung WC, Ong TG, Li WS. Preparation and characterization of amino-linked heterocyclic carbene palladium, gold, and silver complexes and their use as anticancer agents that act by triggering apoptotic cell death. Journal of Medicinal Chemistry. 54: 5245-9. PMID 21671598 DOI: 10.1021/Jm101096X |
0.238 |
|
2006 |
Kuo L, Chang HC, Leu TH, Maa MC, Hung WC. Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway. Journal of Cellular Physiology. 207: 729-34. PMID 16453304 DOI: 10.1002/jcp.20616 |
0.236 |
|
2017 |
Chu PY, Jiang SS, Shan YS, Hung WC, Chen MH, Lin HY, Chen YL, Tsai HJ, Chen LT. Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors. Oncotarget. 8: 103613-103625. PMID 29262588 DOI: 10.18632/oncotarget.21665 |
0.236 |
|
2006 |
Chang HC, Cho CY, Hung WC. Silencing of the metastasis suppressor RECK by RAS oncogene is mediated by DNA methyltransferase 3b-induced promoter methylation. Cancer Research. 66: 8413-20. PMID 16951151 DOI: 10.1158/0008-5472.CAN-06-0685 |
0.235 |
|
2009 |
Chen WT, Hung WC, Kang WY, Huang YC, Su YC, Yang CH, Chai CY. Overexpression of cyclooxygenase-2 in urothelial carcinoma in conjunction with tumor-associated-macrophage infiltration, hypoxia-inducible factor-1alpha expression, and tumor angiogenesis. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 117: 176-84. PMID 19245590 DOI: 10.1111/j.1600-0463.2008.00004.x |
0.235 |
|
2011 |
Chen JY, Wang MC, Hung WC. Bcr-Abl-induced tyrosine phosphorylation of Emi1 to stabilize Skp2 protein via inhibition of ubiquitination in chronic myeloid leukemia cells. Journal of Cellular Physiology. 226: 407-13. PMID 20717963 DOI: 10.1002/jcp.22346 |
0.233 |
|
2012 |
Wei S, Chu PC, Chuang HC, Hung WC, Kulp SK, Chen CS. Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent. Plos One. 7: e47298. PMID 23071779 DOI: 10.1371/Journal.Pone.0047298 |
0.233 |
|
2019 |
Kuo TL, Cheng KH, Shan YS, Chen LT, Hung WC. β-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer. Theranostics. 9: 324-336. PMID 30809277 DOI: 10.7150/thno.28201 |
0.232 |
|
2008 |
Hung WC. Anti-metastatic action of non-steroidal anti-inflammatory drugs Kaohsiung Journal of Medical Sciences. 24: 392-397. PMID 18926952 DOI: 10.1016/S1607-551X(08)70162-1 |
0.231 |
|
2015 |
Chen HM, Tsai CH, Hung WC. Foretinib inhibits angiogenesis, lymphangiogenesis and tumor growth of pancreatic cancer in vivo by decreasing VEGFR-2/3 and TIE-2 signaling. Oncotarget. 6: 14940-52. PMID 25909285 DOI: 10.18632/ONCOTARGET.3613 |
0.23 |
|
2018 |
Hsu MC, Hung WC. Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling. Molecular Cancer. 17: 35. PMID 29455645 DOI: 10.1186/s12943-018-0791-3 |
0.229 |
|
2009 |
Chen JY, Wang MC, Hung WC. Transcriptional activation of Skp2 by BCR-ABL in K562 chronic myeloid leukemia cells. Leukemia Research. 33: 1520-4. PMID 19329185 DOI: 10.1016/j.leukres.2009.03.007 |
0.228 |
|
2016 |
Yin HL, Wu CC, Lin CH, Chai CY, Hou MF, Chang SJ, Tsai HP, Hung WC, Pan MR, Luo CW. β1 Integrin as a Prognostic and Predictive Marker in Triple-Negative Breast Cancer. International Journal of Molecular Sciences. 17. PMID 27589736 DOI: 10.3390/ijms17091432 |
0.226 |
|
2011 |
Huang YC, Hung WC, Chye SM, Chen WT, Chai CY. para-Phenylenediamine-induced autophagy in human uroepithelial cell line mediated mutant p53 and activation of ERK signaling pathway. Toxicology in Vitro : An International Journal Published in Association With Bibra. 25: 1630-7. PMID 21741467 DOI: 10.1016/j.tiv.2011.06.013 |
0.226 |
|
2011 |
Pan MR, Peng G, Hung WC, Lin SY. Monoubiquitination of H2AX protein regulates DNA damage response signaling. The Journal of Biological Chemistry. 286: 28599-607. PMID 21676867 DOI: 10.1074/jbc.M111.256297 |
0.224 |
|
2018 |
Luo CW, Hsiao IL, Wang JY, Wu CC, Hung WC, Lin YH, Chen TY, Hsu YC, Cheng TL, Pan MR. Cell Motility Facilitated by Mono(2-ethylhexyl) Phthalate via Activation of the AKT-β-Catenin-IL-8 Axis in Colorectal Cancer. Journal of Agricultural and Food Chemistry. PMID 30188700 DOI: 10.1021/acs.jafc.8b03558 |
0.222 |
|
2012 |
Pan MR, Hsieh HJ, Dai H, Hung WC, Li K, Peng G, Lin SY. Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment. The Journal of Biological Chemistry. 287: 6764-72. PMID 22219182 DOI: 10.1074/jbc.M111.287037 |
0.22 |
|
2018 |
Hsu MC, Pan MR, Chu PY, Tsai YL, Tsai CH, Shan YS, Chen LT, Hung WC. Protein Arginine Methyltransferase 3 Enhances Chemoresistance in Pancreatic Cancer by Methylating hnRNPA1 to Increase ABCG2 Expression. Cancers. 11. PMID 30577570 DOI: 10.3390/cancers11010008 |
0.22 |
|
2013 |
Cheng HT, Hung WC. Inhibition of lymphangiogenic factor VEGF-C expression and production by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in breast cancer cells. Oncology Reports. 29: 1238-44. PMID 23242251 DOI: 10.3892/or.2012.2188 |
0.219 |
|
2019 |
Pan MR, Hou MF, Ou-Yang F, Wu CC, Chang SJ, Hung WC, Yip HK, Luo CW. FAK is Required for Tumor Metastasis-Related Fluid Microenvironment in Triple-Negative Breast Cancer. Journal of Clinical Medicine. 8. PMID 30609732 DOI: 10.3390/jcm8010038 |
0.217 |
|
2009 |
Hung WC, Tseng WL, Shiea J, Chang HC. Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells. Cancer Letters. 288: 156-61. PMID 19625121 DOI: 10.1016/j.canlet.2009.06.032 |
0.216 |
|
2002 |
Pan MR, Hung WC. Nonsteroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 via suppression of the ERK/Sp1-mediated transcription. The Journal of Biological Chemistry. 277: 32775-80. PMID 12087091 DOI: 10.1074/jbc.M202334200 |
0.214 |
|
2009 |
Hung WC, Chang HC. Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells. Journal of Agricultural and Food Chemistry. 57: 76-82. PMID 19061309 DOI: 10.1021/jf802881d |
0.214 |
|
2008 |
Pan MR, Chang HC, Hung WC. Non-steroidal anti-inflammatory drugs suppress the ERK signaling pathway via block of Ras/c-Raf interaction and activation of MAP kinase phosphatases. Cellular Signalling. 20: 1134-41. PMID 18374541 DOI: 10.1016/j.cellsig.2008.02.004 |
0.213 |
|
2008 |
Yang CH, Hung WC, Wang SL, Kang WY, Chen WT, Huang YC, Su YC, Chai CY. Immunoexpression and prognostic role of hTERT and cyclin D1 in urothelial carcinoma. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 116: 309-16. PMID 18397466 DOI: 10.1111/j.1600-0463.2008.00905.x |
0.209 |
|
2007 |
Chuang TD, Guh JY, Chiou SJ, Chen HC, Hung WC, Chuang LY. Sp1 and Smad3 are required for high glucose-induced p21(WAF1) gene transcription in LLC-PK1 cells. Journal of Cellular Biochemistry. 102: 1190-201. PMID 17516505 DOI: 10.1002/jcb.21346 |
0.208 |
|
2003 |
Chang HC, Hung WC, Huang MS, Hsu HK. Extract from the leaves of Toona sinensis roemor exerts potent antiproliferative effect on human lung cancer cells. The American Journal of Chinese Medicine. 30: 307-14. PMID 12230019 DOI: 10.1142/S0192415X02000223 |
0.206 |
|
2014 |
Wang CH, Chen CL, More SV, Hsiao PW, Hung WC, Li WS. The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family. Plos One. 9: e101088. PMID 24967704 DOI: 10.1371/Journal.Pone.0101088 |
0.205 |
|
2003 |
Hung W, Liu L, Chang H. P-316 Histone deacetylase inhibitor suppresses MMP-2 activation and cell invasion via RECK Lung Cancer. 41: S172. DOI: 10.1016/S0169-5002(03)92284-7 |
0.205 |
|
2005 |
Chang HC, Liu LT, Hung WC. Involvement of histone deacetylation in ras-induced down-regulation of the metastasis suppressor RECK. Cellular Signalling. 16: 675-9. PMID 15093608 DOI: 10.1016/J.CELLSIG.2003.11.001 |
0.203 |
|
2014 |
Chang YW, Su CM, Su YH, Ho YS, Lai HH, Chen HA, Kuo ML, Hung WC, Chen YW, Wu CH, Chen PS, Su JL. Novel peptides suppress VEGFR-3 activity and antagonize VEGFR-3-mediated oncogenic effects. Oncotarget. 5: 3823-35. PMID 25003617 DOI: 10.18632/ONCOTARGET.1709 |
0.203 |
|
2017 |
Hung W, Chiang C. Up-regulation of sialyltransferases increases lymphatic metastasis in pancreatic cancer via the integrin-mediated pathway Pancreatology. 17: S19. DOI: 10.1016/J.PAN.2017.05.060 |
0.201 |
|
2013 |
Cheng HT, Hung WC. Inhibition of proliferation, sprouting, tube formation and Tie2 signaling of lymphatic endothelial cells by the histone deacetylase inhibitor SAHA. Oncology Reports. 30: 961-7. PMID 23754070 DOI: 10.3892/or.2013.2523 |
0.2 |
|
2020 |
Chen JY, Li CF, Lai YS, Hung WC. Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth. British Journal of Cancer. PMID 33024266 DOI: 10.1038/s41416-020-01112-z |
0.196 |
|
2020 |
Chang TM, Chu PY, Hung WC, Shan YS, Lin HY, Huang KW, Chang JS, Chen LT, Tsai HJ. c-Myc promotes lymphatic metastasis of pancreatic neuroendocrine tumor through VEGFC upregulation. Cancer Science. PMID 33128283 DOI: 10.1111/cas.14717 |
0.194 |
|
2019 |
Kuo TL, Cheng KH, Chen LT, Hung WC. Deciphering The Potential Role of Hox Genes in Pancreatic Cancer. Cancers. 11. PMID 31137902 DOI: 10.3390/cancers11050734 |
0.193 |
|
2008 |
Hsu MC, Huang CC, Chang HC, Hu TH, Hung WC. Overexpression of Jab1 in hepatocellular carcinoma and its inhibition by peroxisome proliferator-activated receptor{gamma} ligands in vitro and in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4045-52. PMID 18593980 DOI: 10.1158/1078-0432.CCR-07-5040 |
0.19 |
|
2020 |
Li YL, Chen CH, Chen JY, Lai YS, Wang SC, Jiang SS, Hung WC. Single-cell analysis reveals immune modulation and metabolic switch in tumor-draining lymph nodes. Oncoimmunology. 9: 1830513. PMID 33117603 DOI: 10.1080/2162402X.2020.1830513 |
0.189 |
|
2014 |
Jian SF, Hsiao CC, Chen SY, Weng CC, Kuo TL, Wu DC, Hung WC, Cheng KH. Utilization of liquid chromatography mass spectrometry analyses to identify LKB1-APC interaction in modulating Wnt/β-catenin pathway of lung cancer cells. Molecular Cancer Research : McR. 12: 622-35. PMID 24448687 DOI: 10.1158/1541-7786.MCR-13-0487 |
0.188 |
|
2018 |
Chan SH, Tsai KW, Chiu SY, Kuo WH, Chen HY, Jiang SS, Chang KJ, Hung WC, Wang LH. Identification of the novel role of CD24 as an oncogenesis regulator and therapeutic target for Triple Negative Breast Cancer. Molecular Cancer Therapeutics. PMID 30381446 DOI: 10.1158/1535-7163.Mct-18-0292 |
0.187 |
|
2012 |
Lu MH, Huang CC, Pan MR, Chen HH, Hung WC. Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6416-25. PMID 23045246 DOI: 10.1158/1078-0432.CCR-12-0832 |
0.186 |
|
2017 |
Luo CW, Wang JY, Hung WC, Peng G, Tsai YL, Chang TM, Chai CY, Lin CH, Pan MR. G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 28351524 DOI: 10.1016/j.radonc.2017.03.002 |
0.185 |
|
2006 |
Cheng HT, Chen JY, Huang YC, Chang HC, Hung WC. Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex. Journal of Cellular Biochemistry. 98: 1450-6. PMID 16518840 DOI: 10.1002/jcb.20780 |
0.185 |
|
2015 |
Pan MR, Hsu MC, Chen LT, Hung WC. G9a orchestrates PCL3 and KDM7A to promote histone H3K27 methylation. Scientific Reports. 5: 18709. PMID 26688070 DOI: 10.1038/srep18709 |
0.184 |
|
2019 |
Weng CC, Hsieh MJ, Wu CC, Lin YC, Shan YS, Hung WC, Chen LT, Cheng KH. Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer. Molecular Cancer. 18: 96. PMID 31109321 DOI: 10.1186/s12943-019-1023-1 |
0.184 |
|
2016 |
Pan MR, Hsu MC, Luo CW, Chen LT, Shan YS, Hung WC. The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer. Oncotarget. PMID 27531902 DOI: 10.18632/oncotarget.11256 |
0.183 |
|
2006 |
Huang YC, Hung WC. 1,25-dihydroxyvitamin D3 transcriptionally represses p45Skp2 expression via the Sp1 sites in human prostate cancer cells. Journal of Cellular Physiology. 209: 363-9. PMID 16883603 DOI: 10.1002/jcp.20741 |
0.182 |
|
2014 |
Chen JY, Li CF, Kuo CC, Tsai KK, Hou MF, Hung WC. Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression. Breast Cancer Research : Bcr. 16: 410. PMID 25060643 DOI: 10.1186/s13058-014-0410-1 |
0.182 |
|
2016 |
Pan MR, Li K, Lin SY, Hung WC. Connecting the Dots: From DNA Damage and Repair to Aging. International Journal of Molecular Sciences. 17. PMID 27164092 DOI: 10.3390/ijms17050685 |
0.18 |
|
2005 |
Lee CI, Guh JY, Chen HC, Lin KH, Yang YL, Hung WC, Lai YH, Chuang LY. Leptin and connective tissue growth factor in advanced glycation end-product-induced effects in NRK-49F cells. Journal of Cellular Biochemistry. 93: 940-50. PMID 15389880 DOI: 10.1002/jcb.20222 |
0.179 |
|
2014 |
Yen YC, Shiah SG, Chu HC, Hsu YM, Hsiao JR, Chang JY, Hung WC, Liao CT, Cheng AJ, Lu YC, Chen YW. Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells. Molecular Cancer. 13: 6. PMID 24410957 DOI: 10.1186/1476-4598-13-6 |
0.178 |
|
2008 |
Chang CK, Hung WC, Chang HC. The Kazal motifs of RECK protein inhibit MMP-9 secretion and activity and reduce metastasis of lung cancer cells in vitro and in vivo Journal of Cellular and Molecular Medicine. 12: 2781-2789. PMID 18194466 DOI: 10.1111/j.1582-4934.2008.00215.x |
0.173 |
|
2014 |
Chen YW, Hsiao PJ, Weng CC, Kuo KK, Kuo TL, Wu DC, Hung WC, Cheng KH. SMAD4 loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells. Bmc Cancer. 14: 181. PMID 24625091 DOI: 10.1186/1471-2407-14-181 |
0.173 |
|
2015 |
Hung W, Chen H, Tsai C. Inhibition of pancreatic cancer by a kinase inhibitor by targeting mutiple signaling pathways Pancreatology. 15: S35-S36. DOI: 10.1016/J.PAN.2015.05.154 |
0.168 |
|
2016 |
Chen JY, Lai YS, Tsai HJ, Kuo CC, Yen BL, Yeh SP, Sun HS, Hung WC. The oncometabolite R-2-hydroxyglutarate activates NF-κB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells. Scientific Reports. 6: 32428. PMID 27577048 DOI: 10.1038/srep32428 |
0.168 |
|
2012 |
Pan M, Chen L, Hung W. Potential role of KLF10 in the regulation of gemcitabine resistance in pancreatic cancer cells Pancreatology. 12: 510-511. DOI: 10.1016/J.PAN.2012.11.030 |
0.165 |
|
2020 |
Kan JY, Moi SH, Hung WC, Hou MF, Chen FM, Shih SL, Shiau JP, Li CL, Chiang CP. Comprehensive Transcriptomic Analysis Identifies as a Survival-Related Sialyltransferase Gene in Breast Cancer. Genes. 11. PMID 33260650 DOI: 10.3390/genes11121436 |
0.164 |
|
2018 |
Hung W, Hsu M, Chen L. AB108. P082. Role of epigenetic modifying enzymes in the chemoresistance of pancreatic cancer Annals of Pancreatic Cancer. 1: AB108-AB108. DOI: 10.21037/apc.2018.ab108 |
0.163 |
|
2019 |
Hsu MC, Pan MR, Hung WC. Two Birds, One Stone: Double Hits on Tumor Growth and Lymphangiogenesis by Targeting Vascular Endothelial Growth Factor Receptor 3. Cells. 8. PMID 30901976 DOI: 10.3390/cells8030270 |
0.162 |
|
2018 |
Weng CC, Ding PY, Liu YH, Hawse JR, Subramaniam M, Wu CC, Lin YC, Chen CY, Hung WC, Cheng KH. Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis. Oncogene. PMID 30467381 DOI: 10.1038/s41388-018-0575-7 |
0.154 |
|
2018 |
Wang HC, Hung WC, Chen LT, Pan MR. From Friend to Enemy: Dissecting the Functional Alteration of Immunoregulatory Components during Pancreatic Tumorigenesis. International Journal of Molecular Sciences. 19. PMID 30428588 DOI: 10.3390/ijms19113584 |
0.153 |
|
2004 |
Huang YC, Chen JY, Hung WC. Vitamin D3 receptor/Sp1 complex is required for the induction of p27Kip1 expression by vitamin D3. Oncogene. 23: 4856-61. PMID 15064717 DOI: 10.1038/sj.onc.1207621 |
0.15 |
|
2003 |
Chang HC, Huang YC, Hung WC. Antiproliferative and chemopreventive effects of adlay seed on lung cancer in vitro and in vivo. Journal of Agricultural and Food Chemistry. 51: 3656-60. PMID 12769541 DOI: 10.1021/jf021142a |
0.147 |
|
2015 |
Yeh HH, Tseng YF, Hsu YC, Lan SH, Wu SY, Raghavaraju G, Cheng DE, Lee YR, Chang TY, Chow NH, Hung WC, Liu HS. Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity. Bmc Cancer. 15: 172. PMID 25885317 DOI: 10.1186/s12885-015-1155-7 |
0.143 |
|
2004 |
Chang HC, Hung WC, Chuang YJ, Jong YJ. Degradation of survival motor neuron (SMN) protein is mediated via the ubiquitin/proteasome pathway. Neurochemistry International. 45: 1107-12. PMID 15337310 DOI: 10.1016/j.neuint.2004.04.005 |
0.141 |
|
2019 |
Hung YH, Hsu MC, Chen LT, Hung WC, Pan MR. Alteration of Epigenetic Modifiers in Pancreatic Cancer and Its Clinical Implication. Journal of Clinical Medicine. 8. PMID 31238554 DOI: 10.3390/jcm8060903 |
0.141 |
|
2015 |
Weng CC, Kuo KK, Su HT, Hsiao PJ, Chen YW, Wu DC, Hung WC, Cheng KH. Pancreatic Tumor Progression Associated With CD133 Overexpression: Involvement of Increased TERT Expression and Epidermal Growth Factor Receptor-Dependent Akt Activation. Pancreas. PMID 26646272 DOI: 10.1097/MPA.0000000000000460 |
0.137 |
|
2015 |
Chiang NJ, Shan YS, Hung WC, Chen LT. Epigenetic regulation in the carcinogenesis of cholangiocarcinoma. The International Journal of Biochemistry & Cell Biology. PMID 26100596 DOI: 10.1016/j.biocel.2015.06.012 |
0.132 |
|
2017 |
Pan MR, Hsu MC, Chen LT, Hung WC. Orchestration of H3K27 methylation: mechanisms and therapeutic implication. Cellular and Molecular Life Sciences : Cmls. PMID 28717873 DOI: 10.1007/s00018-017-2596-8 |
0.126 |
|
2013 |
Yang ST, Yen CJ, Lai CH, Lin YJ, Chang KC, Lee JC, Liu YW, Chang-Liao PY, Hsu LS, Chang WC, Hung WC, Tang TK, Liu YW, Hung LY. SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC. Journal of Hepatology. 58: 1157-64. PMID 23369793 DOI: 10.1016/j.jhep.2013.01.025 |
0.124 |
|
1999 |
Hung WC, Chang HC, Chuang LY. Transforming growth factor beta 1 potently activates CPP32-like proteases in human hepatoma cells. Cellular Signalling. 10: 511-5. PMID 9754720 DOI: 10.1016/S0898-6568(97)00189-7 |
0.117 |
|
2019 |
Hsu MC, Tsai YL, Lin CH, Pan MR, Shan YS, Cheng TY, Cheng SH, Chen LT, Hung WC. Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer. Journal of Hematology & Oncology. 12: 79. PMID 31324208 DOI: 10.1186/s13045-019-0769-7 |
0.116 |
|
2005 |
Lee CI, Guh JY, Chen HC, Hung WC, Yang YL, Chuang LY. Advanced glycation end-product-induced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells. Journal of Cellular Biochemistry. 95: 281-92. PMID 15770649 DOI: 10.1002/jcb.20380 |
0.116 |
|
2013 |
Chiang CH, Hou MF, Hung WC. Up-regulation of miR-182 by β-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK. Biochimica Et Biophysica Acta. 1830: 3067-76. PMID 23333633 DOI: 10.1016/j.bbagen.2013.01.009 |
0.112 |
|
2017 |
Tsai H, Chang T, Shan Y, Chu P, Jiang SS, Hung W, Chen Y, Tu H, Chen L. The regulatory role of PTEN and LKB1 on mTOR pathway in pancreatic neuroendocrien tumors Pancreatology. 17: S11. DOI: 10.1016/j.pan.2017.05.035 |
0.104 |
|
2007 |
Yang YL, Chang SM, Wu CC, Hsieh PW, Chen SL, Chang FR, Hung WC, Issa HH, Wu YC. Cytotoxic sesquiterpene lactones from Pseudoelephantopus spicatus. Journal of Natural Products. 70: 1761-5. PMID 17970595 DOI: 10.1021/NP070331Q |
0.104 |
|
2007 |
Hsieh PW, Huang ZY, Chen JH, Chang FR, Wu CC, Yang YL, Chiang MY, Yen MH, Chen SL, Yen HF, Lübken T, Hung WC, Wu YC. Cytotoxic withanolides from Tubocapsicum anomalum. Journal of Natural Products. 70: 747-53. PMID 17417907 DOI: 10.1021/np0605541 |
0.099 |
|
2008 |
Lee CL, Chang FR, Hsieh PW, Chiang MY, Wu CC, Huang ZY, Lan YH, Chen M, Lee KH, Yen HF, Hung WC, Wu YC. Cytotoxic ent-abietane diterpenes from Gelonium aequoreum. Phytochemistry. 69: 276-87. PMID 17714747 DOI: 10.1016/j.phytochem.2007.07.005 |
0.099 |
|
2007 |
Peng JP, Chang HC, Hwang CF, Hung WC. Retraction to "Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with lymph node metastasis" [Oral Oncol. 41 (2005) 903-908]. Oral Oncology. 42: 653. PMID 16892492 DOI: 10.1016/J.ORALONCOLOGY.2006.06.003 |
0.097 |
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2008 |
Chen YL, Lan YH, Hsieh PW, Wu CC, Chen SL, Yen CT, Chang FR, Hung WC, Wu YC. Bioactive cembrane diterpenoids of Anisomeles indica. Journal of Natural Products. 71: 1207-12. PMID 18547115 DOI: 10.1021/np800147z |
0.09 |
|
2012 |
Hung L, Yang S, Chang K, Yen C, Lin Y, Chang-Liao P, Tsou J, Hung W, Tang T, Liu Y. 374 CPAP is a Novel Transcriptional Co-activator of NF-κB European Journal of Cancer. 48: 114. DOI: 10.1016/S0959-8049(12)72172-X |
0.086 |
|
2017 |
Cho YT, Su H, Chiang YY, Shiea J, Yuan SF, Hung WC, Yeh YT, Hou MF. Fine Needle Aspiration Combined With Matrix-assisted Laser Desorption Ionization Time-of-Flight/Mass Spectrometry to Characterize Lipid Biomarkers for Diagnosing Accuracy of Breast Cancer. Clinical Breast Cancer. PMID 28648841 DOI: 10.1016/j.clbc.2017.04.014 |
0.074 |
|
2008 |
Shiea J, Yuan CH, Huang MZ, Cheng SC, Ma YL, Tseng WL, Chang HC, Hung WC. Detection of native protein ions in aqueous solution under ambient conditions by electrospray laser desorption/ionization mass spectrometry. Analytical Chemistry. 80: 4845-52. PMID 18510347 DOI: 10.1021/ac702108t |
0.071 |
|
2010 |
Chuang KH, Wang HE, Cheng TC, Tzou SC, Tseng WL, Hung WC, Tai MH, Chang TK, Roffler SR, Cheng TL. Development of a universal anti-polyethylene glycol reporter gene for noninvasive imaging of PEGylated probes. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 933-41. PMID 20484433 DOI: 10.2967/jnumed.109.071977 |
0.063 |
|
2004 |
Guh JY, Chuang TD, Chen HC, Hung WC, Lai YH, Shin SJ, Chuang LY. Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3. Kidney International. 64: 2041-51. PMID 14633126 DOI: 10.1046/J.1523-1755.2003.00330.X |
0.061 |
|
2010 |
Hung WW, Hassan IN, Yamin BM, Kassim MB. 1,1'-Diphenyl-3,3'-(p-phenyl-enedicarbon-yl)dithio-urea. Acta Crystallographica. Section E, Structure Reports Online. 66: o314. PMID 21579744 DOI: 10.1107/S1600536809055834 |
0.051 |
|
2010 |
Wu DC, Hsu PI, Wu JY, Opekun AR, Kuo CH, Wu IC, Wang SS, Chen A, Hung WC, Graham DY. Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 8: 36-41.e1. PMID 19804842 DOI: 10.1016/j.cgh.2009.09.030 |
0.041 |
|
2011 |
Kung Pui L, Hung WW, M Yamin B, Kassim MB. 3,3'',4,4''-Tetra-meth-oxy-1,1':4',1''-terphen-yl. Acta Crystallographica. Section E, Structure Reports Online. 67: o1892. PMID 22090943 DOI: 10.1107/S1600536811025207 |
0.031 |
|
2010 |
Kuo CH, Wang SS, Hsu WH, Kuo FC, Weng BC, Li CJ, Hsu PI, Chen A, Hung WC, Yang YC, Wang WM, Wu DC. Rabeprazole can overcome the impact of CYP2C19 polymorphism on quadruple therapy. Helicobacter. 15: 265-72. PMID 20633187 DOI: 10.1111/j.1523-5378.2010.00761.x |
0.01 |
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