| Year |
Citation |
Score |
| 2024 |
Arriaga JM, Ronaldson-Bouchard K, Picech F, Nunes de Almeida F, Afari S, Chhouri H, Vunjak-Novakovic G, Abate-Shen C. In vivo genome-wide CRISPR screening identifies CITED2 as a driver of prostate cancer bone metastasis. Oncogene. PMID 38454137 DOI: 10.1038/s41388-024-02995-5 |
0.362 |
|
| 2024 |
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Socciarelli F, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Dinalankara W, Jere M, Valencia I, ... ... Abate-Shen C, et al. Distinct mesenchymal cell states mediate prostate cancer progression. Nature Communications. 15: 363. PMID 38191471 DOI: 10.1038/s41467-023-44210-1 |
0.388 |
|
| 2023 |
Papachristodoulou A, Heidegger I, Virk RK, Di Bernardo M, Kim JY, Laplaca C, Picech F, Schäfer G, De Castro GJ, Hibshoosh H, Loda M, Klocker H, Rubin MA, Zheng T, Benson MC, ... ... Abate-Shen C, et al. Metformin Overcomes the Consequences of NKX3.1 Loss to Suppress Prostate Cancer Progression. European Urology. PMID 37659962 DOI: 10.1016/j.eururo.2023.07.016 |
0.412 |
|
| 2023 |
Li JJ, Vasciaveo A, Karagiannis D, Sun Z, Chen X, Socciarelli F, Frankenstein Z, Zou M, Pannellini T, Chen Y, Gardner K, Robinson BD, de Bono J, Abate-Shen C, Rubin MA, et al. NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer. Biorxiv : the Preprint Server For Biology. PMID 37502956 DOI: 10.1101/2023.07.18.549585 |
0.399 |
|
| 2023 |
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Jere M, Unkenholz C, Alexanderani MK, Khani F, ... ... Abate-Shen C, et al. Distinct mesenchymal cell states mediate prostate cancer progression. Biorxiv : the Preprint Server For Biology. PMID 37034687 DOI: 10.1101/2023.03.29.534769 |
0.462 |
|
| 2023 |
Floc'h N, Kinkade CW, Kobayashi T, Aytes A, Lefebvre C, Mitrofanova A, Cardiff RD, Califano A, Shen MM, Abate-Shen C. Editor's Note: Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model. Cancer Research. 83: 1160. PMID 37014043 DOI: 10.1158/0008-5472.CAN-23-0516 |
0.338 |
|
| 2023 |
Ouyang X, Jessen WJ, Al-Ahmadie H, Serio AM, Lin Y, Shih WJ, Reuter VE, Scardino PT, Shen MM, Aronow BJ, Vickers AJ, Gerald WL, Abate-Shen C. Editor's Note: Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer. Cancer Research. 83: 1161. PMID 37014042 DOI: 10.1158/0008-5472.CAN-23-0515 |
0.4 |
|
| 2022 |
Vasciaveo A, Arriaga JM, Nunes de Almeida F, Zou M, Douglass EF, Picech F, Shibata M, Rodriguez-Calero A, de Brot S, Mitrofanova A, Chua CW, Karan C, Realubit R, Pampou S, Kim JY, ... ... Abate-Shen C, et al. OncoLoop: A network-based precision cancer medicine framework. Cancer Discovery. PMID 36374194 DOI: 10.1158/2159-8290.CD-22-0342 |
0.334 |
|
| 2022 |
Abate-Shen C, Nunes de Almeida F. Establishment of the LNCaP Cell Line - The Dawn of an Era for Prostate Cancer Research. Cancer Research. 82: 1689-1691. PMID 35502546 DOI: 10.1158/0008-5472.CAN-22-1065 |
0.431 |
|
| 2022 |
Papachristodoulou A, Abate-Shen C. Precision intervention for prostate cancer: Re-evaluating who is at risk. Cancer Letters. 538: 215709. PMID 35490919 DOI: 10.1016/j.canlet.2022.215709 |
0.36 |
|
| 2021 |
Lopez-Bujanda ZA, Haffner MC, Chaimowitz MG, Chowdhury N, Venturini NJ, Patel RA, Obradovic A, Hansen CS, Jacków J, Maynard JP, Sfanos KS, Abate-Shen C, Bieberich CJ, Hurley PJ, Selby MJ, et al. Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression. Nature Cancer. 2: 803-818. PMID 35122025 DOI: 10.1038/s43018-021-00227-3 |
0.335 |
|
| 2021 |
Park S, Rong L, Owczarek TB, Di Bernardo M, Shoulson RL, Chua CW, Kim JY, Lankarani A, Chakrapani P, Syed T, McKiernan JM, Solit DB, Shen MM, Al-Ahmadie HA, Abate-Shen C. Novel mouse models of bladder cancer identify a prognostic signature associated with risk of disease progression. Cancer Research. PMID 34470779 DOI: 10.1158/0008-5472.CAN-21-1254 |
0.345 |
|
| 2021 |
Papachristodoulou A, Rodriguez-Calero A, Panja S, Margolskee E, Virk RK, Milner TA, Pina Martina L, Kim JY, Di Bernardo M, Williams AB, Maliza EA, Caputo JM, Haas C, Wang V, De Castro GJ, ... ... Abate-Shen C, et al. NKX3.1 localization to mitochondria suppresses prostate cancer initiation. Cancer Discovery. PMID 33893149 DOI: 10.1158/2159-8290.CD-20-1765 |
0.386 |
|
| 2021 |
Paull EO, Aytes A, Jones SJ, Subramaniam PS, Giorgi FM, Douglass EF, Tagore S, Chu B, Vasciaveo A, Zheng S, Verhaak R, Abate-Shen C, Alvarez MJ, Califano A. A modular master regulator landscape controls cancer transcriptional identity. Cell. PMID 33434495 DOI: 10.1016/j.cell.2020.11.045 |
0.304 |
|
| 2020 |
Arriaga JM, Panja S, Alshalalfa M, Zhao J, Zou M, Giacobbe A, Madubata CJ, Yeji Kim J, Rodriguez A, Coleman I, Virk RK, Hibshoosh H, Ertunc O, Ozbek B, Fountain J, ... ... Abate-Shen C, et al. A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance. Nature Cancer. 1: 1082-1096. PMID 34085047 DOI: 10.1038/s43018-020-00125-0 |
0.401 |
|
| 2020 |
Leibold J, Ruscetti M, Cao Z, Ho YJ, Baslan T, Zou M, Abida W, Feucht J, Han T, Barriga FM, Tsanov KM, Zamechek L, Kulick A, Amor C, Tian S, ... ... Abate-Shen C, et al. Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis. Cancer Discovery. PMID 32376773 DOI: 10.1158/2159-8290.Cd-19-1242 |
0.528 |
|
| 2020 |
Mardis ER, Ribas A, Hait WN, Jaffee EM, Foti M, Abate-Shen C, Albini A, Bernards R, Cruz-Correa MR, Flaherty KT, Greenberg PD, June CH, Knudsen KE, Liu ET, Mills GB, et al. AACR calls on congress to take immediate action against COVID-19 and protect patients with cancer during the pandemic Cancer Discovery. 10: 771-774. PMID 32295764 DOI: 10.1158/2159-8290.Cd-20-0449 |
0.346 |
|
| 2020 |
Rong L, Abate-Shen C. Abstract A28: Deregulation of KMT2D promotes squamous differentiation in a mouse model of muscle-invasive bladder cancer Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Bladder19-A28 |
0.47 |
|
| 2020 |
Abate-Shen C. Abstract IA12: From mouse to man: Dissecting cancer mechanisms using mouse models Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia12 |
0.551 |
|
| 2020 |
Arriaga JM, Panja S, Alshalalfa M, Zhao J, Zou M, Giacobbe A, Madubata CJ, Kim JY, Rodriguez A, Coleman I, Virk RK, Hibshoosh H, Ertunc O, Ozbek B, Fountain J, ... ... Abate-Shen C, et al. A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance Nature Cancer. 1: 1082-1096. DOI: 10.1038/s43018-020-00125-0 |
0.314 |
|
| 2018 |
Lippman SM, Abate-Shen C, Colbert Maresso KL, Colditz GA, Dannenberg AJ, Davidson NE, Disis ML, DuBois RN, Szabo E, Giuliano AR, Hait WN, Lee JJ, Kensler TW, Kramer BS, Limburg P, et al. AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health. Cancer Prevention Research (Philadelphia, Pa.). 11: 735-778. PMID 30530635 DOI: 10.1158/1940-6207.Capr-18-0421 |
0.391 |
|
| 2018 |
Aytes A, Giacobbe A, Mitrofanova A, Ruggero K, Cyrta J, Arriaga J, Palomero L, Farran-Matas S, Rubin MA, Shen MM, Califano A, Abate-Shen C. NSD2 is a conserved driver of metastatic prostate cancer progression. Nature Communications. 9: 5201. PMID 30518758 DOI: 10.1038/S41467-018-07511-4 |
0.554 |
|
| 2018 |
Le Magnen C, Virk RK, Dutta A, Kim JY, Panja S, Lopez-Bujanda ZA, Califano A, Drake CG, Mitrofanova A, Abate-Shen C. Cooperation of loss of and inflammation in prostate cancer initiation. Disease Models & Mechanisms. PMID 30266798 DOI: 10.1242/Dmm.035139 |
0.547 |
|
| 2018 |
Abate-Shen C. Prostate Cancer Metastasis - Fueled by Fat? The New England Journal of Medicine. 378: 1643-1645. PMID 29694822 DOI: 10.1056/Nejmcibr1800808 |
0.515 |
|
| 2018 |
Arriaga JM, Abate-Shen C. Genetically Engineered Mouse Models of Prostate Cancer in the Postgenomic Era. Cold Spring Harbor Perspectives in Medicine. PMID 29661807 DOI: 10.1101/Cshperspect.A030528 |
0.521 |
|
| 2018 |
Lee SH, Hu W, Matulay JT, Silva MV, Owczarek TB, Kim K, Chua CW, Barlow LJ, Kandoth C, Williams AB, Bergren SK, Pietzak EJ, Anderson CB, Benson MC, Coleman JA, ... ... Abate-Shen C, et al. Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer. Cell. 173: 515-528.e17. PMID 29625057 DOI: 10.1016/J.Cell.2018.03.017 |
0.37 |
|
| 2018 |
Abate-Shen C, Rubin MA. Decision letter: Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death Elife. DOI: 10.7554/Elife.37294.026 |
0.315 |
|
| 2018 |
Arriaga JM, Abate-Shen C. Abstract B01: A genetically engineered mouse model of de novo bone metastasis Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B01 |
0.442 |
|
| 2018 |
Zou M, Vasciaveo A, Califano A, Abate-Shen C. Abstract 3017: Identifying drivers for advanced prostate cancer by a transposon-based genetic screen Cancer Research. 78: 3017-3017. DOI: 10.1158/1538-7445.Am2018-3017 |
0.508 |
|
| 2018 |
Dutta A, Abate-Shen C. Abstract 2412: The nuclear homeoprotein NKX3.1, has a novel function in the mitochondria in regulation of prostate cancer initiation Cancer Research. 78: 2412-2412. DOI: 10.1158/1538-7445.Am2018-2412 |
0.463 |
|
| 2017 |
Zou M, Toivanen R, Mitrofanova A, Floc'h N, Hayati S, Sun Y, Le Magnen C, Chester D, Mostaghel EA, Califano A, Rubin MA, Shen MM, Abate-Shen C. Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-resistant Prostate Cancer. Cancer Discovery. PMID 28411207 DOI: 10.1158/2159-8290.Cd-16-1174 |
0.492 |
|
| 2017 |
Dutta A, Panja S, Virk RK, Kim JY, Zott R, Cremers S, Golombos DM, Liu D, Mosquera JM, Mostaghel EA, Barbieri CE, Mitrofanova A, Abate-Shen C. Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition. European Urology. PMID 28385453 DOI: 10.1016/J.Eururo.2017.03.031 |
0.49 |
|
| 2017 |
Owczarek TB, Kobayashi T, Ramirez R, Rong L, Puzio-Kuter AM, Iyer G, Teo MY, Sanchez-Vega F, Wang J, Schultz N, Zheng T, Solit DB, Al-Ahmadie HA, Abate-Shen C. ARF confers a context-dependent response to chemotherapy in muscle invasive bladder cancer. Cancer Research. PMID 28082400 DOI: 10.1158/0008-5472.Can-16-2621 |
0.394 |
|
| 2017 |
Rong L, Owczarek T, Kobayashi T, Abate-Shen C. Abstract 3175: Context-dependent role of ARF for response to chemotherapy in muscle invasive bladder cancer Cancer Research. 77: 3175-3175. DOI: 10.1158/1538-7445.Am2017-3175 |
0.336 |
|
| 2017 |
Ruggero K, Giacobbe A, Mitrofanova A, Calvet A, Palomero L, Pujana M, Califano A, Abate-Shen C, Aytes A. Epigenetic mechanisms and therapeutic opportunities in metastatic castration resistant prostate cancer European Urology Supplements. 16: e249-e250. DOI: 10.1016/S1569-9056(17)30215-4 |
0.486 |
|
| 2016 |
Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate-Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science (New York, N.Y.). 352: 1576-80. PMID 27339988 DOI: 10.1126/Science.Aad9512 |
0.51 |
|
| 2016 |
Le Magnen C, Dutta A, Abate-Shen C. Optimizing mouse models for precision cancer prevention. Nature Reviews. Cancer. 16: 187-96. PMID 26893066 DOI: 10.1038/Nrc.2016.1 |
0.404 |
|
| 2016 |
Santanam U, Banach-Petrosky W, Abate-Shen C, Shen MM, White E, DiPaola RS. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes & Development. 30: 399-407. PMID 26883359 DOI: 10.1101/Gad.274134.115 |
0.506 |
|
| 2016 |
McKiernan JM, Onyeji I, Lascano D, Ahn J, Desai N, Abate-Shen C, Holder DD, RoyChoudhury A, Chang S, DeCastro GJ. A phase I/II study of albumin-bound rapamycin nanoparticles in the treatment of bacillus calmette-guerin refractory non-muscle invasive transitional cell bladder cancer. Journal of Clinical Oncology. 34: e16008-e16008. DOI: 10.1200/Jco.2016.34.15_Suppl.E16008 |
0.33 |
|
| 2016 |
Zou M, Toivanen R, Mitrofanova A, Shen MM, Abate-Shen C. Abstract 4387: Alterations of TP53 mediate resistance to abiraterone in castration-resistant prostate cancer Cancer Research. 76: 4387-4387. DOI: 10.1158/1538-7445.Am2016-4387 |
0.423 |
|
| 2016 |
Magnen CL, Dutta A, Mitrofanova A, Califano A, Abate-Shen C. Abstract 2888: Identification of an NKX3.1-G9a-UTY regulatory network that controls proper prostate differentiation Cancer Research. 76: 2888-2888. DOI: 10.1158/1538-7445.Am2016-2888 |
0.532 |
|
| 2015 |
Mitrofanova A, Aytes A, Zou M, Shen MM, Abate-Shen C, Califano A. Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models. Cell Reports. PMID 26387954 DOI: 10.1016/J.Celrep.2015.08.051 |
0.463 |
|
| 2015 |
Kobayashi T, Owczarek TB, McKiernan JM, Abate-Shen C. Modelling bladder cancer in mice: opportunities and challenges. Nature Reviews. Cancer. 15: 42-54. PMID 25533675 DOI: 10.1038/Nrc3858 |
0.417 |
|
| 2015 |
Magnen CL, Dutta A, Abate-Shen C. Abstract 88: The Nkx3.1 homeobox gene maintains prostatic identity while its loss leads to prostate cancer initiation Cancer Research. 75: 88-88. DOI: 10.1158/1538-7445.Am2015-88 |
0.531 |
|
| 2014 |
Wang J, Abate-Shen C. Analyses of tumor-suppressor genes in germline mouse models of cancer. Cold Spring Harbor Protocols. 2014: 807-12. PMID 25086022 DOI: 10.1101/Pdb.Top069773 |
0.403 |
|
| 2014 |
Aytes A, Mitrofanova A, Lefebvre C, Alvarez MJ, Castillo-Martin M, Zheng T, Eastham JA, Gopalan A, Pienta KJ, Shen MM, Califano A, Abate-Shen C. Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy. Cancer Cell. 25: 638-51. PMID 24823640 DOI: 10.1016/J.Ccr.2014.03.017 |
0.537 |
|
| 2014 |
Abate-Shen C. Abstract IA5: Using cross-species analysis of genome-wide regulatory networks to identify drivers of cancer malignancy Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Ia5 |
0.505 |
|
| 2014 |
Wang J, Aytes A, Abate-Shen C. Abstract B45: Combinatorial activation of PI3-kinase and Ras-Raf signaling in mouse models of advanced prostate cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B45 |
0.485 |
|
| 2014 |
Mitrofanova A, Floch N, Aytes A, Shen M, Abate-Shen C, Califano A. Abstract A29: Interrogating therapeutic response for advanced prostate cancer in vivo using cross-species regulatory models Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-A29 |
0.529 |
|
| 2014 |
Irshad S, Bansal M, Magnen CL, Dillon R, Castillo-Martin M, Zheng T, Aytes A, Wenske S, Guarnieri P, Sumazin P, Benson M, Shen MM, Califano A, Abate-Shen C. Abstract 2873: A molecular signature predictive of indolent prostate cancer Cancer Research. 74: 2873-2873. DOI: 10.1158/1538-7445.Am2014-2873 |
0.508 |
|
| 2014 |
Kobayashi T, Ogawa O, Abate-Shen C. Abstract 1575: ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation Cancer Research. 74: 1575-1575. DOI: 10.1158/1538-7445.Am2014-1575 |
0.364 |
|
| 2013 |
Abate-Shen C, Pandolfi PP. Effective utilization and appropriate selection of genetically engineered mouse models for translational integration of mouse and human trials. Cold Spring Harbor Protocols. 2013. PMID 24173311 DOI: 10.1101/Pdb.Top078774 |
0.356 |
|
| 2013 |
Sawyers CL, Abate-Shen C, Anderson KC, Barker A, Baselga J, Berger NA, Foti M, Jemal A, Lawrence TS, Li CI, Mardis ER, Neumann PJ, Pardoll DM, Prendergast GC, et al. AACR Cancer Progress Report 2013. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: S4-98. PMID 24045178 DOI: 10.1158/1078-0432.Ccr-13-2107 |
0.329 |
|
| 2013 |
Irshad S, Bansal M, Castillo-Martin M, Zheng T, Aytes A, Wenske S, Le Magnen C, Guarnieri P, Sumazin P, Benson MC, Shen MM, Califano A, Abate-Shen C. A molecular signature predictive of indolent prostate cancer. Science Translational Medicine. 5: 202ra122. PMID 24027026 DOI: 10.1126/Scitranslmed.3006408 |
0.472 |
|
| 2013 |
Aytes A, Mitrofanova A, Kinkade CW, Lefebvre C, Lei M, Phelan V, LeKaye HC, Koutcher JA, Cardiff RD, Califano A, Shen MM, Abate-Shen C. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: E3506-15. PMID 23918374 DOI: 10.1073/Pnas.1303558110 |
0.505 |
|
| 2013 |
Kobayashi T, Wang J, Al-Ahmadie H, Abate-Shen C. ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation. Molecular Cancer Research : McR. 11: 828-33. PMID 23817020 DOI: 10.1158/1541-7786.Mcr-13-0207 |
0.312 |
|
| 2013 |
Kruithof-de Julio M, Shibata M, Desai N, Reynon M, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM. Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 1160-71. PMID 23813564 DOI: 10.1002/Dvdy.24008 |
0.455 |
|
| 2013 |
Delto JC, Kobayashi T, Benson M, McKiernan J, Abate-Shen C. Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression. Oncotarget. 4: 269-76. PMID 23563166 DOI: 10.18632/Oncotarget.852 |
0.382 |
|
| 2013 |
Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD. ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity. Molecular Cancer Research : McR. 11: 736-47. PMID 23538858 DOI: 10.1158/1541-7786.Mcr-12-0618 |
0.558 |
|
| 2013 |
Wang ZA, Mitrofanova A, Bergren SK, Abate-Shen C, Cardiff RD, Califano A, Shen MM. Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity. Nature Cell Biology. 15: 274-83. PMID 23434823 DOI: 10.1038/Ncb2697 |
0.461 |
|
| 2013 |
Irshad S, Abate-Shen C. Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic. Cancer Metastasis Reviews. 32: 109-22. PMID 23114843 DOI: 10.1007/S10555-012-9409-1 |
0.526 |
|
| 2013 |
Mitrofanova A, Aytes A, Lefebvre C, Shen M, Abate-Shen C, Califano A. Abstract A26: Cross-species analysis of genome-wide regulatory models elucidates master regulators of prostate cancer progression and treatment response Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A26 |
0.534 |
|
| 2012 |
Floc'h N, Abate-Shen C. The promise of dual targeting Akt/mTOR signaling in lethal prostate cancer. Oncotarget. 3: 1483-4. PMID 23242005 DOI: 10.18632/Oncotarget.771 |
0.494 |
|
| 2012 |
Wang J, Kobayashi T, Floc'h N, Kinkade CW, Aytes A, Dankort D, Lefebvre C, Mitrofanova A, Cardiff RD, McMahon M, Califano A, Shen MM, Abate-Shen C. B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer. Cancer Research. 72: 4765-76. PMID 22836754 DOI: 10.1158/0008-5472.Can-12-0820 |
0.465 |
|
| 2012 |
Floc'h N, Kinkade CW, Kobayashi T, Aytes A, Lefebvre C, Mitrofanova A, Cardiff RD, Califano A, Shen MM, Abate-Shen C. Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model. Cancer Research. 72: 4483-93. PMID 22815528 DOI: 10.1158/0008-5472.Can-12-0283 |
0.471 |
|
| 2012 |
Wang J, Abate-Shen C. The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells. Plos One. 7: e37647. PMID 22629437 DOI: 10.1371/Journal.Pone.0037647 |
0.332 |
|
| 2012 |
Wang J, Abate-Shen C. Transcriptional repression by the Msx1 homeoprotein is associated with global redistribution of the H3K27me3 repressive mark to the nuclear periphery. Nucleus (Austin, Tex.). 3: 155-61. PMID 22555601 DOI: 10.4161/Nucl.19477 |
0.323 |
|
| 2012 |
Aytes A, Mitrofanova A, Lefebvre C, Shen MM, Califano A, Abate-Shen C. Abstract A36: Identification of master regulators driving advanced prostate cancer and treatment response through the assembly of mouse and human prostate cancer interactomes Cancer Research. 72: A36-A36. DOI: 10.1158/1538-7445.Prca2012-A36 |
0.551 |
|
| 2012 |
Aytes A, Mitrofanova A, Lefebvre C, Kinkade CW, Shen MM, Califano A, Abate-Shen C. Abstract LB-405: Identification of master regulators driving advanced prostate cancer and treatment response through the assembly of mouse and human prostate cancer interactomes Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2012-Lb-405 |
0.517 |
|
| 2012 |
Kobayashi T, Delto JC, Abate-Shen C. Abstract 802: A key role for ARF in drug resistance in invasive bladder cancer Cancer Research. 72: 802-802. DOI: 10.1158/1538-7445.Am2012-802 |
0.441 |
|
| 2012 |
Kobayashi T, Delto J, Abate-Shen C. 554 A KEY ROLE FOR ARF IN DRUG RESISTANCE IN INVASIVE BLADDER CANCER Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.629 |
0.436 |
|
| 2011 |
Wang J, Kumar RM, Biggs VJ, Lee H, Chen Y, Kagey MH, Young RA, Abate-Shen C. The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during Development. Developmental Cell. 21: 575-88. PMID 21852201 DOI: 10.1016/J.Devcel.2011.07.003 |
0.342 |
|
| 2011 |
Abate-Shen C, Meneses AA, Kinkade CW, Mitrofanova A, Lefebvre C, Chua CW, Castillo-Martin M, Gelmann E, Shen MM, Califano A. Abstract SY22-01: Interrogating gene expression programs from preclinical analyses of genetically engineered mouse models Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy22-01 |
0.545 |
|
| 2011 |
Wang F, McKeehan WL, Shen MM, Abate-Shen C. Genetically engineered mouse models in prostate cancer research Recent Advances in Prostate Cancer: Basic Science Discoveries and Clinical Advances. 219-282. DOI: 10.1142/9789814329460_0009 |
0.361 |
|
| 2011 |
Shen MM, Wang Z, Wang X, Kruithof-de Julio M, Lei M, Chua CW, Abate-Shen C. Stem cells in prostate regeneration and cancer Developmental Biology. 356: 120. DOI: 10.1016/J.Ydbio.2011.05.063 |
0.469 |
|
| 2011 |
Kobayashi T, Delto J, Castillo-Martin M, Puzio-Kuter A, Cordon-Cardo C, Abate-Shen C. 367 NOVEL P53-INDEPENDENT FUNCTIONS OF ARF IN THE CONTEXT OF COMBINED FUNCTINAL LOSS OF P53 AND PTEN IN A MOUSE MODEL OF INVASIVE BLADDER CANCER Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.453 |
0.355 |
|
| 2010 |
Shen MM, Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes & Development. 24: 1967-2000. PMID 20844012 DOI: 10.1101/Gad.1965810 |
0.514 |
|
| 2010 |
Patel T, Hruby G, Abate-Shen C, Badani K, Mckiernan J. 259 THE IMPACT OF DIABETES AND METFORMIN USE IN CLINICALLY LOCALIZED PROSTATE CANCER TREATED BY RADICAL PROSTATECTOMY Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.318 |
0.423 |
|
| 2009 |
Seager CM, Puzio-Kuter AM, Patel T, Jain S, Cordon-Cardo C, Mc Kiernan J, Abate-Shen C. Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer. Cancer Prevention Research (Philadelphia, Pa.). 2: 1008-14. PMID 19952358 DOI: 10.1158/1940-6207.Capr-09-0169 |
0.41 |
|
| 2009 |
Wang X, Kruithof-de Julio M, Economides KD, Walker D, Yu H, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature. 461: 495-500. PMID 19741607 DOI: 10.1038/Nature08361 |
0.492 |
|
| 2009 |
Couto SS, Cao M, Duarte PC, Banach-Petrosky W, Wang S, Romanienko P, Wu H, Cardiff RD, Abate-Shen C, Cunha GR. Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer. Differentiation; Research in Biological Diversity. 77: 103-11. PMID 19281769 DOI: 10.1016/J.Diff.2008.09.010 |
0.502 |
|
| 2009 |
Puzio-Kuter AM, Castillo-Martin M, Kinkade CW, Wang X, Shen TH, Matos T, Shen MM, Cordon-Cardo C, Abate-Shen C. Inactivation of p53 and Pten promotes invasive bladder cancer. Genes & Development. 23: 675-80. PMID 19261747 DOI: 10.1101/Gad.1772909 |
0.411 |
|
| 2009 |
Abate-Shen C, Shen MM. Diagnostics: The prostate-cancer metabolome. Nature. 457: 799-800. PMID 19212391 DOI: 10.1038/457799A |
0.515 |
|
| 2008 |
Shen MM, Wang X, Economides KD, Walker D, Abate-Shen C. Progenitor cells for the prostate epithelium: roles in development, regeneration, and cancer. Cold Spring Harbor Symposia On Quantitative Biology. 73: 529-38. PMID 19150960 DOI: 10.1101/Sqb.2008.73.050 |
0.504 |
|
| 2008 |
Abate-Shen C, Brown PH, Colburn NH, Gerner EW, Green JE, Lipkin M, Nelson WG, Threadgill D. The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges. Cancer Prevention Research (Philadelphia, Pa.). 1: 161-6. PMID 19138951 DOI: 10.1158/1940-6207.Capr-08-0076 |
0.362 |
|
| 2008 |
Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L. BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. Plos One. 3: e3949. PMID 19079609 DOI: 10.1371/Journal.Pone.0003949 |
0.513 |
|
| 2008 |
Wang X, Desai N, Hu YP, Price SM, Abate-Shen C, Shen MM. Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2963-72. PMID 18816836 DOI: 10.1002/Dvdy.21694 |
0.484 |
|
| 2008 |
Kinkade CW, Castillo-Martin M, Puzio-Kuter A, Yan J, Foster TH, Gao H, Sun Y, Ouyang X, Gerald WL, Cordon-Cardo C, Abate-Shen C. Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. The Journal of Clinical Investigation. 118: 3051-64. PMID 18725989 DOI: 10.1172/Jci34764 |
0.509 |
|
| 2008 |
Abate-Shen C, Shen MM, Gelmann E. Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis. Differentiation; Research in Biological Diversity. 76: 717-27. PMID 18557759 DOI: 10.1111/J.1432-0436.2008.00292.X |
0.514 |
|
| 2008 |
Ouyang X, Jessen WJ, Al-Ahmadie H, Serio AM, Lin Y, Shih WJ, Reuter VE, Scardino PT, Shen MM, Aronow BJ, Vickers AJ, Gerald WL, Abate-Shen C. Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer. Cancer Research. 68: 2132-44. PMID 18381418 DOI: 10.1158/0008-5472.Can-07-6055 |
0.537 |
|
| 2008 |
Pienta KJ, Abate-Shen C, Agus DB, Attar RM, Chung LW, Greenberg NM, Hahn WC, Isaacs JT, Navone NM, Peehl DM, Simons JW, Solit DB, Soule HR, VanDyke TA, Weber MJ, et al. The current state of preclinical prostate cancer animal models. The Prostate. 68: 629-39. PMID 18213636 DOI: 10.1002/Pros.20726 |
0.515 |
|
| 2008 |
Abate-Shen C, Kinkade C, Castillo-Martin M, Cordon-Cardo C. 7 INVITED Developing combination therapies for hormone-refractory prostate cancer in a pre-clinical mouse model of the disease European Journal of Cancer Supplements. 6: 7. DOI: 10.1016/S1359-6349(08)71939-6 |
0.352 |
|
| 2007 |
Abate-Shen C, Shen MM. FGF signaling in prostate tumorigenesis--new insights into epithelial-stromal interactions. Cancer Cell. 12: 495-7. PMID 18068626 DOI: 10.1016/J.Ccr.2007.11.021 |
0.505 |
|
| 2007 |
Banach-Petrosky W, Jessen WJ, Ouyang X, Gao H, Rao J, Quinn J, Aronow BJ, Abate-Shen C. Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; Pten mutant mice. Cancer Research. 67: 9089-96. PMID 17909013 DOI: 10.1158/0008-5472.Can-07-2887 |
0.506 |
|
| 2007 |
Shen MM, Abate-Shen C. Pten inactivation and the emergence of androgen-independent prostate cancer. Cancer Research. 67: 6535-8. PMID 17638861 DOI: 10.1158/0008-5472.Can-07-1271 |
0.497 |
|
| 2006 |
Banach-Petrosky W, Ouyang X, Gao H, Nader K, Ji Y, Suh N, DiPaola RS, Abate-Shen C. Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1;Pten mutant mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5895-901. PMID 17020998 DOI: 10.1158/1078-0432.Ccr-06-1039 |
0.433 |
|
| 2006 |
Abate-Shen C. A new generation of mouse models of cancer for translational research. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5274-6. PMID 17000659 DOI: 10.1158/1078-0432.Ccr-06-0500 |
0.39 |
|
| 2006 |
Gao H, Ouyang X, Banach-Petrosky WA, Gerald WL, Shen MM, Abate-Shen C. Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 103: 14477-82. PMID 16973750 DOI: 10.1073/Pnas.0606836103 |
0.506 |
|
| 2006 |
Gao H, Ouyang X, Banach-Petrosky WA, Shen MM, Abate-Shen C. Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice. Cancer Research. 66: 7929-33. PMID 16912166 DOI: 10.1158/0008-5472.Can-06-1637 |
0.512 |
|
| 2006 |
Lee H, Quinn JC, Prasanth KV, Swiss VA, Economides KD, Camacho MM, Spector DL, Abate-Shen C. PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein. Genes & Development. 20: 784-94. PMID 16600910 DOI: 10.1101/Gad.1392006 |
0.336 |
|
| 2005 |
Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis. Cancer Research. 65: 6773-9. PMID 16061659 DOI: 10.1158/0008-5472.Can-05-1948 |
0.466 |
|
| 2005 |
Abate-Shen C, Shen MM. An unusual gene dosage effect of p27kip1 in a mouse model of prostate cancer. Cell Cycle (Georgetown, Tex.). 4: e45-7. PMID 15701964 DOI: 10.4161/Cc.4.3.1530 |
0.538 |
|
| 2005 |
Kuzmichev A, Margueron R, Vaquero A, Preissner TS, Scher M, Kirmizis A, Ouyang X, Brockdorff N, Abate-Shen C, Farnham P, Reinberg D. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 1859-64. PMID 15684044 DOI: 10.1073/Pnas.0409875102 |
0.409 |
|
| 2004 |
Gao H, Ouyang X, Banach-Petrosky W, Borowsky AD, Lin Y, Kim M, Lee H, Shih WJ, Cardiff RD, Shen MM, Abate-Shen C. A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 17204-9. PMID 15569926 DOI: 10.1073/Pnas.0407693101 |
0.483 |
|
| 2004 |
Lee H, Habas R, Abate-Shen C. MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science (New York, N.Y.). 304: 1675-8. PMID 15192231 DOI: 10.1126/Science.1098096 |
0.344 |
|
| 2004 |
Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM. Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Developmental Biology. 267: 387-98. PMID 15013801 DOI: 10.1016/J.Ydbio.2003.11.018 |
0.463 |
|
| 2004 |
Rouzankina I, Abate-Shen C, Niswander L. Dlx genes integrate positive and negative signals during feather bud development. Developmental Biology. 265: 219-33. PMID 14697365 DOI: 10.1016/J.Ydbio.2003.09.023 |
0.333 |
|
| 2003 |
Abate-Shen C. Homeobox genes and cancer: new OCTaves for an old tune. Cancer Cell. 4: 329-30. PMID 14667497 DOI: 10.1016/S1535-6108(03)00277-0 |
0.402 |
|
| 2003 |
Shen MM, Abate-Shen C. Roles of the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 228: 767-78. PMID 14648854 DOI: 10.1002/Dvdy.10397 |
0.499 |
|
| 2003 |
Bendall AJ, Hu G, Levi G, Abate-Shen C. Dlx5 regulates chondrocyte differentiation at multiple stages. The International Journal of Developmental Biology. 47: 335-44. PMID 12895028 DOI: 10.1387/Ijdb.12895028 |
0.556 |
|
| 2003 |
Abate-Shen C, Banach-Petrosky WA, Sun X, Economides KD, Desai N, Gregg JP, Borowsky AD, Cardiff RD, Shen MM. Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Cancer Research. 63: 3886-90. PMID 12873978 |
0.333 |
|
| 2002 |
Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nature Reviews. Cancer. 2: 777-85. PMID 12360280 DOI: 10.1038/Nrc907 |
0.443 |
|
| 2002 |
Park JH, Walls JE, Galvez JJ, Kim M, Abate-Shen C, Shen MM, Cardiff RD. Prostatic intraepithelial neoplasia in genetically engineered mice. The American Journal of Pathology. 161: 727-35. PMID 12163397 DOI: 10.1016/S0002-9440(10)64228-9 |
0.392 |
|
| 2002 |
Abate-Shen C, Shen MM. Mouse models of prostate carcinogenesis. Trends in Genetics : Tig. 18: S1-5. PMID 12047956 DOI: 10.1016/S0168-9525(02)02683-5 |
0.474 |
|
| 2002 |
Kim MJ, Bhatia-Gaur R, Banach-Petrosky WA, Desai N, Wang Y, Hayward SW, Cunha GR, Cardiff RD, Shen MM, Abate-Shen C. Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Research. 62: 2999-3004. PMID 12036903 |
0.417 |
|
| 2002 |
Kim MJ, Cardiff RD, Desai N, Banach-Petrosky WA, Parsons R, Shen MM, Abate-Shen C. Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 2884-9. PMID 11854455 DOI: 10.1073/Pnas.042688999 |
0.505 |
|
| 2001 |
Hu G, Lee H, Price SM, Shen MM, Abate-Shen C. Msx homeobox genes inhibit differentiation through upregulation of cyclin D1. Development (Cambridge, England). 128: 2373-84. PMID 11493556 |
0.526 |
|
| 2000 |
Abate-Shen C, Shen MM. Molecular genetics of prostate cancer. Genes & Development. 14: 2410-34. PMID 11018010 DOI: 10.1101/Gad.819500 |
0.517 |
|
| 2000 |
Bendall AJ, Abate-Shen C. Roles for Msx and Dlx homeoproteins in vertebrate development. Gene. 247: 17-31. PMID 10773441 DOI: 10.1016/S0378-1119(00)00081-0 |
0.364 |
|
| 2000 |
Yan YT, Stein SM, Ding J, Shen MM, Abate-Shen C. A novel PF/PN motif inhibits nuclear localization and DNA binding activity of the ESX1 homeoprotein. Molecular and Cellular Biology. 20: 661-71. PMID 10611245 DOI: 10.1128/Mcb.20.2.661-671.2000 |
0.362 |
|
| 1999 |
Bendall AJ, Ding J, Hu G, Shen MM, Abate-Shen C. Msx1 antagonizes the myogenic activity of Pax3 in migrating limb muscle precursors. Development (Cambridge, England). 126: 4965-76. PMID 10529415 |
0.521 |
|
| 1999 |
Bhatia-Gaur R, Donjacour AA, Sciavolino PJ, Kim M, Desai N, Young P, Norton CR, Gridley T, Cardiff RD, Cunha GR, Abate-Shen C, Shen MM. Roles for Nkx3.1 in prostate development and cancer. Genes & Development. 13: 966-77. PMID 10215624 DOI: 10.1101/Gad.13.8.966 |
0.511 |
|
| 1998 |
Sciavolino PJ, Abate-Shen C. Molecular biology of prostate development and prostate cancer. Annals of Medicine. 30: 357-68. PMID 9783834 DOI: 10.3109/07853899809029935 |
0.514 |
|
| 1998 |
Yang L, Zhang H, Hu G, Wang H, Abate-Shen C, Shen MM. An early phase of embryonic Dlx5 expression defines the rostral boundary of the neural plate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8322-30. PMID 9763476 DOI: 10.1523/Jneurosci.18-20-08322.1998 |
0.543 |
|
| 1998 |
Hu G, Vastardis H, Bendall AJ, Wang Z, Logan M, Zhang H, Nelson C, Stein S, Greenfield N, Seidman CE, Seidman JG, Abate-Shen C. Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis. Molecular and Cellular Biology. 18: 6044-51. PMID 9742121 DOI: 10.1128/Mcb.18.10.6044 |
0.534 |
|
| 1997 |
He WW, Sciavolino PJ, Wing J, Augustus M, Hudson P, Meissner PS, Curtis RT, Shell BK, Bostwick DG, Tindall DJ, Gelmann EP, Abate-Shen C, Carter KC. A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer Genomics. 43: 69-77. PMID 9226374 DOI: 10.1006/geno.1997.4715 |
0.427 |
|
| 1997 |
Sciavolino PJ, Abrams EW, Yang L, Austenberg LP, Shen MM, Abate-Shen C. Tissue-specific expression of murine Nkx3.1 in the male urogenital system Developmental Dynamics. 209: 127-138. PMID 9142502 DOI: 10.1002/(Sici)1097-0177(199705)209:1<127::Aid-Aja12>3.0.Co;2-Z |
0.418 |
|
| 1997 |
Zhang H, Hu G, Wang H, Sciavolino P, Iler N, Shen MM, Abate-Shen C. Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism. Molecular and Cellular Biology. 17: 2920-32. PMID 9111364 DOI: 10.1128/Mcb.17.5.2920 |
0.549 |
|
| 1996 |
Catron KM, Wang H, Hu G, Shen MM, Abate-Shen C. Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy. Mechanisms of Development. 55: 185-99. PMID 8861098 DOI: 10.1016/0925-4773(96)00503-5 |
0.538 |
|
| 1996 |
Zhang H, Catron KM, Abate-Shen C. A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression. Proceedings of the National Academy of Sciences of the United States of America. 93: 1764-9. PMID 8700832 DOI: 10.1073/Pnas.93.5.1764 |
0.325 |
|
| 1996 |
Schnabel CA, Abate-Shen C. Repression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residues. Molecular and Cellular Biology. 16: 2678-88. PMID 8649375 DOI: 10.1128/Mcb.16.6.2678 |
0.31 |
|
| 1995 |
Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C. A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Mechanisms of Development. 53: 87-96. PMID 8555114 DOI: 10.1016/0925-4773(95)00427-0 |
0.322 |
|
| Show low-probability matches. |