| Year |
Citation |
Score |
| 2019 |
Zhang R, Li J, Assaker G, Camirand A, Sabri S, Karaplis AC, Kremer R. Parathyroid Hormone-Related Protein (PTHrP): An Emerging Target in Cancer Progression and Metastasis. Advances in Experimental Medicine and Biology. 1164: 161-178. PMID 31576548 DOI: 10.1007/978-3-030-22254-3_13 |
0.35 |
|
| 2018 |
Zhu Q, Zhou X, Zhu M, Wang Q, Goltzman D, Karaplis A, Miao D. Endogenous Parathyroid Hormone-Related Protein Compensates for the Absence of Parathyroid Hormone in Promoting Bone Accrual In Vivo in a Model of Bone Marrow Ablation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 33: 2239-2241. PMID 30521118 DOI: 10.1002/Jbmr.3582 |
0.462 |
|
| 2018 |
Zhang Y, Chen G, Gu Z, Sun H, Karaplis A, Goltzman D, Miao D. DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide. International Journal of Biological Sciences. 14: 508-517. PMID 29805302 DOI: 10.7150/Ijbs.23318 |
0.481 |
|
| 2018 |
Panda D, Bai X, Sabbagh Y, Zhang Y, Zaun HC, Karellis A, Koromilas AE, Lipman M, Karaplis AC. Defective Interplay Between mTORC1 Activity and Endoplasmic Reticulum Stress-Unfolded Protein Response in Uremic Vascular Calcification. American Journal of Physiology. Renal Physiology. PMID 29357413 DOI: 10.1152/Ajprenal.00350.2017 |
0.322 |
|
| 2017 |
Okumura K, Saito M, Yoshizawa Y, Munakata H, Isogai E, Miura I, Wakana S, Yamaguchi M, Shitara H, Taya C, Karaplis AC, Kominami R, Wakabayashi Y. The parathyroid hormone regulates skin tumour susceptibility in mice. Scientific Reports. 7: 11208. PMID 28894263 DOI: 10.1038/S41598-017-11561-X |
0.348 |
|
| 2017 |
Radi S, Karaplis AC. A Case of Male Osteoporosis: A 37-Year-Old Man with Multiple Vertebral Compression Fractures. Case Reports in Endocrinology. 2017: 6328524. PMID 28791186 DOI: 10.1155/2017/6328524 |
0.333 |
|
| 2017 |
Nguyen-Yamamoto L, Karaplis AC, St-Arnaud R, Goltzman D. Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D. Journal of the American Society of Nephrology : Jasn. 28: 586-597. PMID 27535551 DOI: 10.1681/Asn.2016010066 |
0.382 |
|
| 2016 |
Ma Y, Kirby BJ, Fairbridge NA, Karaplis AC, Lanske B, Kovacs CS. FGF23 is not required to regulate fetal phosphorus metabolism but exerts effects within 12 hours after birth. Endocrinology. en20161369. PMID 27929669 DOI: 10.1210/En.2016-1369 |
0.361 |
|
| 2016 |
Camirand A, Goltzman D, Gupta A, Kaouass M, Panda D, Karaplis A. The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development. Plos One. 11: e0160034. PMID 27463808 DOI: 10.1371/Journal.Pone.0160034 |
0.445 |
|
| 2016 |
Zhou X, Dai X, Wu X, Ji J, Karaplis A, Goltzman D, Yang X, Miao D. Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment. Scientific Reports. 6: 29171. PMID 27373231 DOI: 10.1038/Srep29171 |
0.429 |
|
| 2016 |
Sun W, Wu J, Huang L, Liu H, Wang R, Karaplis A, Goltzman D, Miao D. PTHrP nuclear localization and carboxyl terminus sequences modulate dental and mandibular development in part via the action of p27. Endocrinology. en20151555. PMID 26859332 DOI: 10.1210/En.2015-1555 |
0.381 |
|
| 2016 |
Bai X, Miao D, Xiao S, Qiu D, St-Arnaud R, Petkovich M, Gupta A, Goltzman D, Karaplis AC. CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders. The Journal of Clinical Investigation. PMID 26784541 DOI: 10.1172/Jci81928 |
0.398 |
|
| 2015 |
Jiang M, Chen G, Lu N, Zhang Y, Jin S, Karaplis A, Goltzman D, Miao D. Deficiency of the PTHrP Nuclear Localization and Carboxyl Terminal Sequences Leads to Pre-mature Skin Aging Partially Mediated by the Upregulation of p27. Experimental Dermatology. PMID 26121068 DOI: 10.1111/Exd.12789 |
0.333 |
|
| 2015 |
Hirai T, Kobayashi T, Nishimori S, Karaplis AC, Goltzman D, Kronenberg HM. Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis. Endocrinology. 156: 2774-80. PMID 26052897 DOI: 10.1210/En.2014-1835 |
0.438 |
|
| 2015 |
Zhu M, Zhang J, Dong Z, Zhang Y, Wang R, Karaplis A, Goltzman D, Miao D. The p27 Pathway Modulates the Regulation of Skeletal Growth and Osteoblastic Bone Formation by Parathyroid Hormone-Related Peptide. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25917430 DOI: 10.1002/Jbmr.2544 |
0.461 |
|
| 2014 |
Boras-Granic K, Dann P, VanHouten J, Karaplis A, Wysolmerski J. Deletion of the Nuclear Localization Sequences and C-Terminus of PTHrP Impairs Embryonic Mammary Development but also Inhibits PTHrP Production Plos One. 9. PMID 24785493 DOI: 10.1371/Journal.Pone.0090418 |
0.454 |
|
| 2014 |
Ma Y, Samaraweera M, Cooke-Hubley S, Kirby BJ, Karaplis AC, Lanske B, Kovacs CS. Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization. Endocrinology. 155: 1596-605. PMID 24601885 DOI: 10.1210/En.2013-2061 |
0.38 |
|
| 2013 |
Wang YH, Qiu Y, Han XD, Xiong J, Chen YX, Shi HF, Karaplis A. Haploinsufficiency of endogenous parathyroid hormone-related peptide impairs bone fracture healing. Clinical and Experimental Pharmacology & Physiology. 40: 715-23. PMID 23937065 DOI: 10.1111/1440-1681.12161 |
0.386 |
|
| 2013 |
Raison D, Coquard C, Hochane M, Steger J, Massfelder T, Moulin B, Karaplis AC, Metzger D, Chambon P, Helwig JJ, Barthelmebs M. Knockdown of parathyroid hormone related protein in smooth muscle cells alters renal hemodynamics but not blood pressure. American Journal of Physiology. Renal Physiology. 305: F333-42. PMID 23720345 DOI: 10.1152/Ajprenal.00503.2012 |
0.314 |
|
| 2013 |
Zhu Q, Zhou X, Zhu M, Wang Q, Goltzman D, Karaplis A, Miao D. Endogenous parathyroid hormone-related protein compensates for the absence of parathyroid hormone in promoting bone accrual in vivo in a model of bone marrow ablation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1898-911. PMID 23716486 DOI: 10.1002/Jbmr.2000 |
0.487 |
|
| 2013 |
Liu XL, Lu YS, Gao JY, Marshall C, Xiao M, Miao DS, Karaplis A, Goltzman D, Ding J. Calcium sensing receptor absence delays postnatal brain development via direct and indirect mechanisms. Molecular Neurobiology. 48: 590-600. PMID 23564401 DOI: 10.1007/S12035-013-8448-0 |
0.424 |
|
| 2013 |
Romero JR, Youte R, Brown EM, Pollak MR, Goltzman D, Karaplis A, Pong LC, Chien L, Chattopadhyay N, Rivera A. Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion European Journal of Haematology. 91: 37-45. PMID 23528155 DOI: 10.1111/Ejh.12110 |
0.413 |
|
| 2013 |
Kirby BJ, Ma Y, Martin HM, Buckle Favaro KL, Karaplis AC, Kovacs CS. Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1987-2000. PMID 23505097 DOI: 10.1002/Jbmr.1925 |
0.404 |
|
| 2013 |
Li J, Karaplis AC, Huang DC, Siegel PM, Camirand A, Yang XF, Muller WJ, Kremer R. Abstract 89: Parathyroid Hormone-related Protein (PTHrP) is critical for breast tumour metastasis and may constitute a novel target for therapeutic intervention. Cancer Research. 73: 89-89. DOI: 10.1158/1538-7445.Am2013-89 |
0.349 |
|
| 2012 |
Panda DK, Goltzman D, Karaplis AC. Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor. American Journal of Physiology. Endocrinology and Metabolism. 303: E1489-501. PMID 23092913 DOI: 10.1152/Ajpendo.00254.2012 |
0.503 |
|
| 2012 |
Karaplis AC, Bai X, Falet JP, Macica CM. Mineralizing enthesopathy is a common feature of renal phosphate-wasting disorders attributed to FGF23 and is exacerbated by standard therapy in hyp mice. Endocrinology. 153: 5906-17. PMID 23038738 DOI: 10.1016/J.Semarthrit.2012.12.019 |
0.385 |
|
| 2012 |
Gu Z, Liu Y, Zhang Y, Jin S, Chen Q, Goltzman D, Karaplis A, Miao D. Absence of PTHrP nuclear localization and carboxyl terminus sequences leads to abnormal brain development and function. Plos One. 7: e41542. PMID 22844494 DOI: 10.1371/Journal.Pone.0041542 |
0.358 |
|
| 2012 |
Xue Y, Xiao Y, Liu J, Karaplis AC, Pollak MR, Brown EM, Miao D, Goltzman D. The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice. American Journal of Physiology. Endocrinology and Metabolism. 302: E841-51. PMID 22275754 DOI: 10.1152/Ajpendo.00599.2011 |
0.487 |
|
| 2011 |
Li J, Karaplis AC, Huang DC, Siegel PM, Camirand A, Yang XF, Muller WJ, Kremer R. PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target. The Journal of Clinical Investigation. 121: 4655-69. PMID 22056386 DOI: 10.1172/Jci46134 |
0.345 |
|
| 2011 |
Liu J, Lv F, Sun W, Tao C, Ding G, Karaplis A, Brown E, Goltzman D, Miao D. The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH. Plos Genetics. 7: e1002294. PMID 21966280 DOI: 10.1371/Journal.Pgen.1002294 |
0.481 |
|
| 2011 |
Kremer R, Li J, Camirand A, Karaplis AC. Parathyroid hormone related protein (PTHrP) in tumor progression. Advances in Experimental Medicine and Biology. 720: 145-60. PMID 21901625 DOI: 10.1007/978-1-4614-0254-1_12 |
0.469 |
|
| 2011 |
Ren Y, Liu B, Feng Y, Shu L, Cao X, Karaplis A, Goltzman D, Miao D. Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34). Plos One. 6: e23060. PMID 21829585 DOI: 10.1371/Journal.Pone.0023060 |
0.38 |
|
| 2011 |
Liu P, Chen L, Bai X, Karaplis A, Miao D, Gu N. Impairment of spatial learning and memory in transgenic mice overexpressing human fibroblast growth factor-23. Brain Research. 1412: 9-17. PMID 21824606 DOI: 10.1016/J.Brainres.2011.07.028 |
0.361 |
|
| 2011 |
Shu L, Ji J, Zhu Q, Cao G, Karaplis A, Pollak MR, Brown E, Goltzman D, Miao D. The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1057-71. PMID 21542007 DOI: 10.1002/Jbmr.300 |
0.413 |
|
| 2011 |
Chen L, Liu H, Sun W, Bai X, Karaplis AC, Goltzman D, Miao D. Fibroblast growth factor 23 overexpression impacts negatively on dentin mineralization and dentinogenesis in mice. Clinical and Experimental Pharmacology & Physiology. 38: 395-402. PMID 21488937 DOI: 10.1111/J.1440-1681.2011.05526.X |
0.428 |
|
| 2011 |
Kirby BJ, Ardeshirpour L, Woodrow JP, Wysolmerski JJ, Sims NA, Karaplis AC, Kovacs CS. Skeletal recovery after weaning does not require PTHrP. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1242-51. PMID 21308774 DOI: 10.1002/Jbmr.339 |
0.453 |
|
| 2011 |
Kirby B, Karaplis A, Kovacs C. Calcitriol increases during pregnancy and bone formation upregulates post-lactation without parathyroid hormone Bone. 48: S101-S102. DOI: 10.1016/J.Bone.2011.03.155 |
0.381 |
|
| 2010 |
Sun W, Sun W, Liu J, Zhou X, Xiao Y, Karaplis A, Pollak MR, Brown E, Goltzman D, Miao D. Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice. Development (Cambridge, England). 137: 985-92. PMID 20150282 DOI: 10.1242/Dev.045898 |
0.475 |
|
| 2010 |
Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS. Parathyroid hormone regulates fetal-placental mineral homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 594-605. PMID 19968565 DOI: 10.1359/Jbmr.090825 |
0.447 |
|
| 2010 |
Zhang HW, Ding J, Jin JL, Guo J, Liu JN, Karaplis A, Goltzman D, Miao D. Defects in mesenchymal stem cell self-renewal and cell fate determination lead to an osteopenic phenotype in Bmi-1 null mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 640-52. PMID 19653817 DOI: 10.1359/Jbmr.090812 |
0.468 |
|
| 2010 |
Ji J, Miao D, He B, Karaplis A, Goltzman D. The coordinated action of parathyroid hormone and parathyroid hormone related peptide is essential for normal fetal axial skeletal development Bone. 47: S363. DOI: 10.1016/J.Bone.2010.09.095 |
0.353 |
|
| 2009 |
Liu H, Guo J, Wang L, Chen N, Karaplis A, Goltzman D, Miao D. Distinctive anabolic roles of 1,25-dihydroxyvitamin D(3) and parathyroid hormone in teeth and mandible versus long bones. The Journal of Endocrinology. 203: 203-13. PMID 19713218 DOI: 10.1677/Joe-09-0247 |
0.437 |
|
| 2009 |
Panda D, Goltzman D, Jüppner H, Karaplis AC. TIP39/parathyroid hormone type 2 receptor signaling is a potent inhibitor of chondrocyte proliferation and differentiation. American Journal of Physiology. Endocrinology and Metabolism. 297: E1125-36. PMID 19706789 DOI: 10.1152/Ajpendo.00254.2009 |
0.437 |
|
| 2009 |
Liu P, Bai X, Wang H, Karaplis A, Goltzman D, Miao D. Hypophosphatemia-mediated hypotension in transgenic mice overexpressing human FGF-23. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1514-20. PMID 19684183 DOI: 10.1152/Ajpheart.00581.2009 |
0.389 |
|
| 2009 |
Bai X, Dinghong Q, Miao D, Goltzman D, Karaplis AC. Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype. American Journal of Physiology. Endocrinology and Metabolism. 296: E79-88. PMID 18984852 DOI: 10.1152/Ajpendo.90539.2008 |
0.405 |
|
| 2009 |
Cao G, Gu Z, Ren Y, Shu L, Tao C, Karaplis A, Goltzman D, Miao D. Parathyroid hormone contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium. Endocrinology. 150: 561-9. PMID 18832101 DOI: 10.1210/En.2008-0654 |
0.354 |
|
| 2008 |
Miao D, Su H, He B, Gao J, Xia Q, Zhu M, Gu Z, Goltzman D, Karaplis AC. Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein. Proceedings of the National Academy of Sciences of the United States of America. 105: 20309-14. PMID 19091948 DOI: 10.1073/Pnas.0805690105 |
0.495 |
|
| 2008 |
Gupta A, Välimäki VV, J Välimäki M, Löyttyniemi E, Richard M, L Bukka P, Goltzman D, Karaplis AC. Variable number of tandem repeats polymorphism in parathyroid hormone-related protein as predictor of peak bone mass in young healthy Finnish males. European Journal of Endocrinology / European Federation of Endocrine Societies. 158: 755-64. PMID 18426836 DOI: 10.1530/Eje-07-0886 |
0.429 |
|
| 2008 |
Shu L, Cao G, Ren Y, Karaplis A, Goltzman D, Miao D. The calcium sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone Bone. 43: S49. DOI: 10.1016/J.Bone.2008.08.033 |
0.393 |
|
| 2008 |
Sun W, Liu J, Karaplis A, Goltzman D, Miao D. Alterations in phosphorus, calcium and PTHrP appear to contribute to defects of dental formation in calcium-sensing receptor deficient mice Bone. 43: S49. DOI: 10.1016/J.Bone.2008.08.032 |
0.368 |
|
| 2008 |
Liu J, Tao C, Sun W, Karaplis A, Goltzman D, Miao D. The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus and parathyroid hormone Bone. 43: S31. DOI: 10.1016/J.Bone.2008.07.034 |
0.443 |
|
| 2007 |
Bai X, Miao D, Goltzman D, Karaplis AC. Early lethality in Hyp mice with targeted deletion of Pth gene. Endocrinology. 148: 4974-83. PMID 17615144 DOI: 10.1210/En.2007-0243 |
0.41 |
|
| 2007 |
Gao J, Tiwari-Pandey R, Samadfam R, Yang Y, Miao D, Karaplis AC, Sairam MR, Goltzman D. Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone. Endocrinology. 148: 2613-21. PMID 17332067 DOI: 10.1210/En.2006-1404 |
0.449 |
|
| 2006 |
Xue Y, Karaplis AC, Hendy GN, Goltzman D, Miao D. Exogenous 1,25-dihydroxyvitamin D3 exerts a skeletal anabolic effect and improves mineral ion homeostasis in mice that are homozygous for both the 1alpha-hydroxylase and parathyroid hormone null alleles. Endocrinology. 147: 4801-10. PMID 16857747 DOI: 10.1210/En.2006-0403 |
0.418 |
|
| 2006 |
Hendy GN, Li T, Girard M, Feldstein RC, Mulay S, Desjardins R, Day R, Karaplis AC, Tremblay ML, Canaff L. Targeted ablation of the chromogranin A (Chga) gene: Normal neuroendocrine dense-core secretory granules and increased expression of other granins Molecular Endocrinology. 20: 1935-1947. PMID 16556729 DOI: 10.1210/Me.2005-0398 |
0.435 |
|
| 2005 |
Xue Y, Zhang Z, Karaplis AC, Hendy GN, Goltzman D, Miao D. Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1alpha-hydroxylase and PTH double knockout mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1766-77. PMID 16160734 DOI: 10.1359/Jbmr.050608 |
0.462 |
|
| 2005 |
Miao D, He B, Jiang Y, Kobayashi T, Sorocéanu MA, Zhao J, Su H, Tong X, Amizuka N, Gupta A, Genant HK, Kronenberg HM, Goltzman D, Karaplis AC. Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34. The Journal of Clinical Investigation. 115: 2402-11. PMID 16138191 DOI: 10.1172/Jci24918 |
0.466 |
|
| 2005 |
Bedard N, Hingamp P, Pang Z, Karaplis A, Morales C, Trasler J, Cyr D, Gagnon C, Wing SS. Mice lacking the UBC4-testis gene have a delay in postnatal testis development but normal spermatogenesis and fertility. Molecular and Cellular Biology. 25: 6346-54. PMID 16024774 DOI: 10.1128/Mcb.25.15.6346-6354.2005 |
0.385 |
|
| 2005 |
Xue Y, Karaplis AC, Hendy GN, Goltzman D, Miao D. Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. Human Molecular Genetics. 14: 1515-28. PMID 15843402 DOI: 10.1093/Hmg/Ddi160 |
0.442 |
|
| 2004 |
Sorocéanu MA, Miao D, Bai XY, Su H, Goltzman D, Karaplis AC. Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis. The Journal of Endocrinology. 183: 203-16. PMID 15525588 DOI: 10.1677/Joe.1.05723 |
0.444 |
|
| 2004 |
Bai X, Miao D, Li J, Goltzman D, Karaplis AC. Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders. Endocrinology. 145: 5269-79. PMID 15284207 DOI: 10.1210/En.2004-0233 |
0.391 |
|
| 2004 |
Miao D, Li J, Xue Y, Su H, Karaplis AC, Goltzman D. Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice. Endocrinology. 145: 3554-62. PMID 15090463 DOI: 10.1210/En.2003-1695 |
0.478 |
|
| 2004 |
Miao D, Bai X, Panda DK, Karaplis AC, Goltzman D, McKee MD. Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice. Bone. 34: 638-47. PMID 15050894 DOI: 10.1016/J.Bone.2003.12.015 |
0.421 |
|
| 2004 |
Miao D, He B, Lanske B, Bai XY, Tong XK, Hendy GN, Goltzman D, Karaplis AC. Skeletal abnormalities in Pth-null mice are influenced by dietary calcium. Endocrinology. 145: 2046-53. PMID 14701672 DOI: 10.1210/En.2003-1097 |
0.461 |
|
| 2004 |
Shin HI, Divieti P, Sims NA, Kobayashi T, Miao D, Karaplis AC, Baron R, Bringhurst R, Kronenberg HM. Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro. Endocrinology. 145: 1376-85. PMID 14617570 DOI: 10.1210/En.2003-0839 |
0.439 |
|
| 2004 |
Amizuka N, Henderson JE, White JH, Oda K, Li M, Nozawa-Inoue K, Kawano Y, Suzuki A, Karaplis AC, Goltzman D, Maeda T. Morphological Approach to Biological Action of PTHrP and Vitamin D3 on Endochondral Ossification Journal of Oral Biosciences. 46: 79-96. DOI: 10.1016/S1349-0079(04)80020-3 |
0.497 |
|
| 2003 |
VanHouten JN, Dann P, Stewart AF, Watson CJ, Pollak M, Karaplis AC, Wysolmerski JJ. Mammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactation. The Journal of Clinical Investigation. 112: 1429-36. PMID 14597768 DOI: 10.1172/Jci19504 |
0.49 |
|
| 2003 |
Chan GK, Miao D, Deckelbaum R, Bolivar I, Karaplis A, Goltzman D. Parathyroid hormone-related peptide interacts with bone morphogenetic protein 2 to increase osteoblastogenesis and decrease adipogenesis in pluripotent C3H10T 1/2 mesenchymal cells. Endocrinology. 144: 5511-20. PMID 12960089 DOI: 10.1210/En.2003-0273 |
0.783 |
|
| 2003 |
Kos CH, Karaplis AC, Peng JB, Hediger MA, Goltzman D, Mohammad KS, Guise TA, Pollak MR. The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. The Journal of Clinical Investigation. 111: 1021-8. PMID 12671051 DOI: 10.1172/Jci17416 |
0.426 |
|
| 2003 |
Bai XY, Miao D, Goltzman D, Karaplis AC. The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency. The Journal of Biological Chemistry. 278: 9843-9. PMID 12519781 DOI: 10.1074/Jbc.M210490200 |
0.364 |
|
| 2002 |
Bai X, Miao D, Panda D, Grady S, McKee MD, Goltzman D, Karaplis AC. Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression. Molecular Endocrinology (Baltimore, Md.). 16: 2913-25. PMID 12456809 DOI: 10.1210/Me.2002-0113 |
0.438 |
|
| 2002 |
He B, Tong TK, Hiou-Tim FF, Al-Akad B, Kronenberg HM, Karaplis AC. The murine gene encoding parathyroid hormone: genomic organization, nucleotide sequence and transcriptional regulation. Journal of Molecular Endocrinology. 29: 193-203. PMID 12370121 DOI: 10.1677/Jme.0.0290193 |
0.393 |
|
| 2002 |
Deckelbaum RA, Chan G, Miao D, Goltzman D, Karaplis AC. Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrP-mediated activation of PKA. Journal of Cell Science. 115: 3015-25. PMID 12082161 |
0.743 |
|
| 2002 |
Miao D, He B, Karaplis AC, Goltzman D. Parathyroid hormone is essential for normal fetal bone formation. The Journal of Clinical Investigation. 109: 1173-82. PMID 11994406 DOI: 10.1172/Jci14817 |
0.495 |
|
| 2001 |
Nguyen MT, He B, Karaplis AC. Nuclear Forms of Parathyroid Hormone-Related Peptide Are Translated from Non-AUG Start Sites Downstream from the Initiator Methionine**This work was supported by the Canadian Arthritis Network and the Medical Research Council (MRC) of Canada. Endocrinology. 142: 694-703. PMID 28201336 DOI: 10.1210/Endo.142.2.7944 |
0.352 |
|
| 2001 |
Miao D, Bai X, Panda D, McKee MD, Karaplis AC, Goltzman D. Osteomalacia in Hyp Mice Is Associated with Abnormal Phex Expression and with Altered Bone Matrix Protein Expression and Deposition* *This work was support by Grants MT-5775 (to D.G.) and GR-13297 (to A.C.K.) from the Medical Research Council of Canada, Grant 00731 (to D.G.) from the NCI of Canada, and Grant MT-11360 (to M.D.M.) from the Canadian Institutes for Health Research. Endocrinology. 142: 926-939. PMID 28201145 DOI: 10.1210/Endo.142.2.7976 |
0.478 |
|
| 2001 |
Clemens TL, Cormier S, Eichinger A, Endlich K, Fiaschi-Taesch N, Fischer E, Friedman PA, Karaplis AC, Massfelder T, Rossert J, Schlüter KD, Silve C, Stewart AF, Takane K, Helwig JJ. Parathyroid hormone-related protein and its receptors: Nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets British Journal of Pharmacology. 134: 1113-1136. PMID 11704631 DOI: 10.1038/Sj.Bjp.0704378 |
0.452 |
|
| 2001 |
Chan GK, Deckelbaum RA, Bolivar I, Goltzman D, Karaplis AC. PTHrP inhibits adipocyte differentiation by down-regulating PPAR gamma activity via a MAPK-dependent pathway. Endocrinology. 142: 4900-9. PMID 11606458 DOI: 10.1210/Endo.142.11.8515 |
0.744 |
|
| 2001 |
Karaplis AC. PTHrP: novel roles in skeletal biology. Current Pharmaceutical Design. 7: 655-70. PMID 11375774 |
0.428 |
|
| 2001 |
He B, Deckelbaum RA, Miao D, Lipman ML, Pollak M, Goltzman D, Karaplis AC. Tissue-specific targeting of the pthrp gene: the generation of mice with floxed alleles. Endocrinology. 142: 2070-7. PMID 11316774 DOI: 10.1210/Endo.142.5.8146 |
0.763 |
|
| 2001 |
Miao D, Bai X, Panda D, McKee M, Karaplis A, Goltzman D. Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition. Endocrinology. 142: 926-39. PMID 11159866 DOI: 10.1210/endo.142.2.7976 |
0.385 |
|
| 2000 |
Karaplis AC, Goltzman D. PTH and PTHrP effects on the skeleton. Reviews in Endocrine & Metabolic Disorders. 1: 331-41. PMID 11706747 DOI: 10.1023/A:1026526703898 |
0.336 |
|
| 2000 |
Amizuka N, Henderson JE, White JH, Karaplis AC, Goltzman D, Sasaki T, Ozawa H. Recent studies on the biological action of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in cartilage and bone Histology and Histopathology. 15: 957-970. PMID 10963138 DOI: 10.14670/Hh-15.957 |
0.54 |
|
| 2000 |
Karaplis AC. Metabolic bone disease: Lessons from knockout mice Drug Development Research. 49: 159-166. DOI: 10.1002/(Sici)1098-2299(200003)49:3<159::Aid-Ddr6>3.0.Co;2-L |
0.41 |
|
| 1998 |
Karaplis AC, He B, Nguyen MT, Young ID, Semeraro D, Ozawa H, Amizuka N. Inactivating mutation in the human parathyroid hormone receptor type 1 gene in Blomstrand chondrodysplasia. Endocrinology. 139: 5255-8. PMID 9832466 DOI: 10.1210/Endo.139.12.6522 |
0.411 |
|
| 1998 |
Dunbar ME, Young P, Zhang J, McCaughern-Carucci J, Lanske B, Orloff JJ, Karaplis A, Cunha G, Wysolmerski JJ. Stromal Cells Are Critical Targets in the Regulation of Mammary Ductal Morphogenesis by Parathyroid Hormone-Related Protein Developmental Biology. 203: 75-89. PMID 9806774 DOI: 10.1006/Dbio.1998.9029 |
0.454 |
|
| 1998 |
Philbrick WM, Dreyer BE, Nakchbandi IA, Karaplis AC. Parathyroid hormone-related protein is required for tooth eruption. Proceedings of the National Academy of Sciences of the United States of America. 95: 11846-51. PMID 9751753 DOI: 10.1073/Pnas.95.20.11846 |
0.507 |
|
| 1998 |
Karaplis AC, Deckelbaum RA. Role of PTHrP and PTH-1 receptor in endochondral bone development. Frontiers in Bioscience : a Journal and Virtual Library. 3: d795-803. PMID 9683888 |
0.768 |
|
| 1998 |
Nguyen MT, Karaplis AC. The nucleus: a target site for parathyroid hormone-related peptide (PTHrP) action. Journal of Cellular Biochemistry. 70: 193-9. PMID 9671225 DOI: 10.1002/(Sici)1097-4644(19980801)70:2<193::Aid-Jcb5>3.0.Co;2-J |
0.411 |
|
| 1998 |
Lipman ML, Panda D, Bennett HPJ, Henderson JE, Shane E, Shen Y, Goltzman D, Karaplis AC. Cloning of human PEX cDNA: Expression, subcellular localization, and endopeptidase activity Journal of Biological Chemistry. 273: 13729-13737. PMID 9593714 DOI: 10.1074/Jbc.273.22.13729 |
0.416 |
|
| 1998 |
Beck L, Karaplis AC, Amizuka N, Hewson AS, Ozawa H, Tenenhouse HS. Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proceedings of the National Academy of Sciences of the United States of America. 95: 5372-7. PMID 9560283 DOI: 10.1073/PNAS.95.9.5372 |
0.306 |
|
| 1997 |
Shane E, Parisien M, Henderson JE, Dempster DW, Feldman F, Hardy MA, Tohme JF, Karaplis AC, Clemens TL. Tumor-induced osteomalacia: Clinical and basic studies Journal of Bone and Mineral Research. 12: 1502-1511. PMID 9286768 DOI: 10.1359/Jbmr.1997.12.9.1502 |
0.418 |
|
| 1997 |
Karaplis AC, Vautour L. Parathyroid hormone-related peptide and the parathyroid hormone/parathyroid hormone-related peptide receptor in skeletal development. Current Opinion in Nephrology and Hypertension. 6: 308-13. PMID 9263678 DOI: 10.1097/00041552-199707000-00002 |
0.416 |
|
| 1997 |
Rabbani SA, Harakidas P, Gladu J, Srivastava S, Diarra A, Sauvé R, Karaplis AC, Henderson JE, Goltzman D, Hendy GN. Expression and characterization of recombinant rat parathyroid hormone-related peptide (1-141) and an amino-terminally-truncated analogue (38-141) Molecular and Cellular Endocrinology. 130: 13-21. PMID 9220017 DOI: 10.1016/S0303-7207(97)00068-3 |
0.365 |
|
| 1996 |
Kovacs CS, Lanske B, Hunzelman JL, Guo J, Karaplis AC, Kronenberg HM. Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor. Proceedings of the National Academy of Sciences of the United States of America. 93: 15233-8. PMID 8986793 DOI: 10.1073/Pnas.93.26.15233 |
0.358 |
|
| 1996 |
Karaplis AC, Kronenberg HM. Physiological roles for parathyroid hormone-related protein: lessons from gene knockout mice. Vitamins and Hormones. 52: 177-93. PMID 8909161 DOI: 10.1016/S0083-6729(08)60411-2 |
0.464 |
|
| 1996 |
Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV. Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 137: 5109-18. PMID 8895385 DOI: 10.1210/Endo.137.11.8895385 |
0.509 |
|
| 1996 |
Amizuka N, Henderson JE, Hoshi K, Warshawsky H, Ozawa H, Goltzman D, Karaplis AC. Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion Endocrinology. 137: 5055-5067. PMID 8895380 DOI: 10.1210/Endo.137.11.8895380 |
0.462 |
|
| 1996 |
Henderson JE, He B, Goltzman D, Karaplis AC. Constitutive expression of parathyroid hormone-related peptide (PTHrP) stimulates growth and inhibit differentiation of CFK2 chondrocytes Journal of Cellular Physiology. 169: 33-41. PMID 8841420 DOI: 10.1002/(Sici)1097-4652(199610)169:1<33::Aid-Jcp4>3.0.Co;2-F |
0.419 |
|
| 1996 |
Sidler B, Alpert L, Henderson JE, Deckelbaum R, Amizuka N, Silva JE, Goltzman D, Karaplis AC. Amplification of the parathyroid hormone-related peptide gene in a colonic carcinoma Journal of Clinical Endocrinology and Metabolism. 81: 2841-2847. PMID 8768840 DOI: 10.1210/Jcem.81.8.8768840 |
0.721 |
|
| 1996 |
Kronenberg HM, Karaplis AC, Lanske B. Role of parathyroid hormone-related protein in skeletal development. Annals of the New York Academy of Sciences. 785: 119-23. PMID 8702116 DOI: 10.1111/J.1749-6632.1996.Tb56249.X |
0.34 |
|
| 1996 |
Lanske B, Karaplis AC, Lee K, Luz A, Vortkamp A, Pirro A, Karperien M, Defize LH, Ho C, Mulligan RC, Abou-Samra AB, Jüppner H, Segre GV, Kronenberg HM. PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth. Science (New York, N.Y.). 273: 663-6. PMID 8662561 DOI: 10.1126/Science.273.5275.663 |
0.505 |
|
| 1996 |
Amizuka N, Karaplis AC, Henderson JE, Warshawsky H, Lipman ML, Matsuki Y, Ejiri S, Tanaka M, Izumi N, Ozawa H, Goltzman D. Haploinsufficiency of parathyroid hormone-related peptide (PTHrP) results in abnormal postnatal bone development Developmental Biology. 175: 166-176. PMID 8608863 DOI: 10.1006/Dbio.1996.0104 |
0.493 |
|
| 1995 |
Karaplis AC, Lim SK, Baba H, Arnold A, Kronenberg HM. Inefficient membrane targeting, translocation, and proteolytic processing by signal peptidase of a mutant preproparathyroid hormone protein. The Journal of Biological Chemistry. 270: 1629-35. PMID 7829495 DOI: 10.1074/Jbc.270.4.1629 |
0.332 |
|
| 1995 |
Henderson JE, Amizuka N, Warshawsky H, Biasotto D, Lanske BMK, Goltzman D, Karaplis AC. Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death Molecular and Cellular Biology. 15: 4064-4075. PMID 7623802 DOI: 10.1128/Mcb.15.8.4064 |
0.417 |
|
| 1994 |
Karaplis AC, Luz A, Glowacki J, Bronson RT, Tybulewicz VL, Kronenberg HM, Mulligan RC. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes & Development. 8: 277-89. PMID 8314082 DOI: 10.1101/Gad.8.3.277 |
0.496 |
|
| 1994 |
Amizuka N, Warshawsky H, Henderson JE, Goltzman D, Karaplis AC. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation Journal of Cell Biology. 126: 1611-1623. PMID 8089190 DOI: 10.1083/Jcb.126.6.1611 |
0.472 |
|
| 1993 |
Schipani E, Karga H, Karaplis AC, Potts JT, Kronenberg HM, Segre GV, Abou-Samra AB, Jüppner H. Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology. 132: 2157-65. PMID 8386612 DOI: 10.1210/Endo.132.5.8386612 |
0.387 |
|
| 1992 |
Schipani E, Abou-Samra A, Karaplis A, Kronenberg H, Segre G, Jüppner H. Molecular cloning of human PTH/PTHrP receptor cDNAs Bone and Mineral. 17: 126. DOI: 10.1016/0169-6009(92)91843-8 |
0.306 |
|
| 1991 |
Kremer R, Karaplis AC, Henderson J, Gulliver W, Banville D, Hendy GN, Goltzman D. Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes: Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion Journal of Clinical Investigation. 87: 884-893. PMID 1999499 DOI: 10.1172/Jci115094 |
0.383 |
|
| 1990 |
Karaplis AC, Yasuda T, Hendy GN, Goltzman D, Banville D. Gene-encoding parathyroid hormone-like peptide: nucleotide sequence of the rat gene and comparison with the human homologue. Molecular Endocrinology (Baltimore, Md.). 4: 441-6. PMID 2342478 DOI: 10.1210/Mend-4-3-441 |
0.328 |
|
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