Patrick M. Flood - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Immunology, Cell Biology

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sharma M, Arbabzada N, Flood PM. Mechanism underlying β2-AR agonist-mediated phenotypic conversion of LPS-activated microglial cells. Journal of Neuroimmunology. 332: 37-48. PMID 30933849 DOI: 10.1016/J.Jneuroim.2019.03.017  0.451
2018 Sharma M, Flood PM. β-arrestin2 regulates the anti-inflammatory effects of Salmeterol in lipopolysaccharide-stimulated BV2 cells. Journal of Neuroimmunology. 325: 10-19. PMID 30352316 DOI: 10.1016/J.Jneuroim.2018.10.001  0.477
2018 Kaur H, Siraki AG, Sharma M, Uludağ H, Dederich DN, Flood P, El-Bialy T. Reactive Oxygen Species Mediate Therapeutic Ultrasound-Induced, Mitogen-Activated Protein Kinase Activation in C28/I2 Chondrocytes. Ultrasound in Medicine & Biology. PMID 30037475 DOI: 10.1016/J.Ultrasmedbio.2018.05.025  0.348
2017 Kaur H, Siraki AG, Uludağ H, Dederich DN, Flood P, El-Bialy T. Role of Reactive Oxygen Species during Low-Intensity Pulsed Ultrasound Application in MC-3 T3 E1 Pre-osteoblast Cell Culture. Ultrasound in Medicine & Biology. PMID 28807447 DOI: 10.1016/J.Ultrasmedbio.2017.07.002  0.34
2017 Sharma M, Patterson L, Chapman E, Flood PM. Salmeterol; A Long Acting β2-Aderenergic Receptor Agonist Inhibits Macrophage Activation by Lipopolysaccharide From Porphyromonas Gingivalis. Journal of Periodontology. 1-17. PMID 28398147 DOI: 10.1902/Jop.2017.160464  0.431
2014 Habineza Ndikuyeze G, Gaurnier-Hausser A, Patel R, Baldwin AS, May MJ, Flood P, Krick E, Propert KJ, Mason NJ. A phase I clinical trial of systemically delivered NEMO binding domain peptide in dogs with spontaneous activated B-cell like diffuse large B-cell lymphoma. Plos One. 9: e95404. PMID 24798348 DOI: 10.1371/Journal.Pone.0095404  0.32
2014 Peterson L, Ismond KP, Chapman E, Flood P. Potential benefits of therapeutic use of β2-adrenergic receptor agonists in neuroprotection and Parkinsonμs disease. Journal of Immunology Research. 2014: 103780. PMID 24741572 DOI: 10.1155/2014/103780  0.331
2012 Peterson LJ, Flood PM. Oxidative stress and microglial cells in Parkinson's disease. Mediators of Inflammation. 2012: 401264. PMID 22544998 DOI: 10.1155/2012/401264  0.421
2011 Flood PM, Qian L, Peterson LJ, Zhang F, Shi JS, Gao HM, Hong JS. Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease. Parkinson's Disease. 2011: 216298. PMID 21603248 DOI: 10.4061/2011/216298  0.409
2011 Qian L, Wu HM, Chen SH, Zhang D, Ali SF, Peterson L, Wilson B, Lu RB, Hong JS, Flood PM. β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway. Journal of Immunology (Baltimore, Md. : 1950). 186: 4443-54. PMID 21335487 DOI: 10.4049/Jimmunol.1002449  0.48
2010 Qian L, Flood PM, Hong JS. Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 971-9. PMID 20571837 DOI: 10.1007/S00702-010-0428-1  0.379
2010 Zhang F, Qian L, Flood PM, Shi JS, Hong JS, Gao HM. Inhibition of IkappaB kinase-beta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity. The Journal of Pharmacology and Experimental Therapeutics. 333: 822-33. PMID 20190013 DOI: 10.1124/Jpet.110.165829  0.442
2009 Wu HM, Tzeng NS, Qian L, Wei SJ, Hu X, Chen SH, Rawls SM, Flood P, Hong JS, Lu RB. Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2344-57. PMID 19536110 DOI: 10.1038/Npp.2009.64  0.43
2009 Tchivileva IE, Tan KS, Gambarian M, Nackley AG, Medvedev AV, Romanov S, Flood PM, Maixner W, Makarov SS, Diatchenko L. Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes. Molecular Immunology. 46: 2256-66. PMID 19477016 DOI: 10.1016/J.Molimm.2009.04.008  0.367
2009 Zhang D, Hu X, Qian L, Wilson B, Lee C, Flood P, Langenbach R, Hong JS. Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro. Toxicology and Applied Pharmacology. 238: 64-70. PMID 19397918 DOI: 10.1016/J.Taap.2009.04.015  0.406
2009 Qian L, Hu X, Zhang D, Snyder A, Wu HM, Li Y, Wilson B, Lu RB, Hong JS, Flood PM. beta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway. Glia. 57: 1600-9. PMID 19330844 DOI: 10.1002/Glia.20873  0.471
2009 Zhang F, Qian L, Flood PM, Hong J-, Gao H. P2.175 Sorafenib protects dopaminergic neurons from lipopolysaccharide-induced neurotoxicity via NF-úB inactivation Parkinsonism & Related Disorders. 15. DOI: 10.1016/S1353-8020(09)70526-7  0.348
2008 Qian L, Wei SJ, Zhang D, Hu X, Xu Z, Wilson B, El-Benna J, Hong JS, Flood PM. Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia. Journal of Immunology (Baltimore, Md. : 1950). 181: 660-8. PMID 18566433 DOI: 10.4049/Jimmunol.181.1.660  0.428
2008 Qian L, Flood PM. Microglial cells and Parkinson's disease. Immunologic Research. 41: 155-64. PMID 18512160 DOI: 10.1007/S12026-008-8018-0  0.429
2008 Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS. Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration? Environmental Health Perspectives. 116: 593-8. PMID 18470306 DOI: 10.1289/Ehp.11031  0.416
2008 Qian L, Hong J-, Flood PM. Salmeterol, a long-acting β2-adrenergic receptor agonist, is neuroprotective through inhibition of microglial NADPH oxidase European Journal of Pharmaceutical Sciences. 34. DOI: 10.1016/J.Ejps.2008.02.089  0.306
2007 Qian L, Gao X, Pei Z, Wu X, Block M, Wilson B, Hong JS, Flood PM. NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation. Parkinsonism & Related Disorders. 13: S316-20. PMID 18267257 DOI: 10.1016/S1353-8020(08)70023-3  0.435
2007 Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM. Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase. Journal of Neuroinflammation. 4: 23. PMID 17880684 DOI: 10.1186/1742-2094-4-23  0.477
2007 Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM. Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity. Journal of Immunology (Baltimore, Md. : 1950). 179: 1198-209. PMID 17617613 DOI: 10.4049/Jimmunol.179.2.1198  0.392
2007 Tan KS, Nackley AG, Satterfield K, Maixner W, Diatchenko L, Flood PM. Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cellular Signalling. 19: 251-60. PMID 16996249 DOI: 10.1016/J.Cellsig.2006.06.007  0.408
2006 Qian L, Hong JS, Flood PM. Role of microglia in inflammation-mediated degeneration of dopaminergic neurons: neuroprotective effect of interleukin 10. Journal of Neural Transmission-Supplement. 367-71. PMID 17017555 DOI: 10.1007/978-3-211-45295-0_56  0.456
2006 Tan KS, Qian L, Rosado R, Flood PM, Cooper LF. The role of titanium surface topography on J774A.1 macrophage inflammatory cytokines and nitric oxide production. Biomaterials. 27: 5170-7. PMID 16808973 DOI: 10.1016/J.Biomaterials.2006.05.002  0.369
2006 Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase. The Journal of Pharmacology and Experimental Therapeutics. 319: 44-52. PMID 16807359 DOI: 10.1124/Jpet.106.106351  0.424
1992 Flood PM, Washington O, Stevens DP, Ptak W. Immunological signals which control T cell responses Journal of Endodontics. 18: 435-439. PMID 9796511 DOI: 10.1016/S0099-2399(06)80844-7  0.329
1991 Bristow CL, Lyford LK, Stevens DP, Flood PM. Elastase is a constituent product of T cells. Biochemical and Biophysical Research Communications. 181: 232-9. PMID 1958192 DOI: 10.1016/S0006-291X(05)81407-X  0.3
1990 Flood PM, Dougherty JP, Ron Y. Inhibition of Ly-6A antigen expression prevents T cell activation Journal of Experimental Medicine. 172: 115-120. PMID 2141625 DOI: 10.1084/Jem.172.1.115  0.361
1988 Green DR, Chue B, Flood PM. Induction of contrasuppression is restricted by genes mapping to the IgH locus. Immunologic Research. 7: 82-92. PMID 2897413 DOI: 10.1007/Bf02918156  0.352
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