| Year |
Citation |
Score |
| 2015 |
Huang H, Chen S, Van Doren J, Li D, Farichon C, He Y, Zhang Q, Zhang K, Conney AH, Goodin S, Du Z, Zheng X. α-Tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells. Molecular Medicine Reports. 11: 4573-8. PMID 25625536 DOI: 10.3892/Mmr.2015.3238 |
0.41 |
|
| 2015 |
Wang H, Li D, Du Z, Huang MT, Cui X, Lu Y, Li C, Woo SL, Conney AH, Zheng X, Zhang K. Antioxidant and anti-inflammatory properties of Chinese ilicifolius vegetable (Acanthopanax trifoliatus (L) Merr) and its reference compounds Food Science and Biotechnology. 24: 1131-1138. DOI: 10.1007/S10068-015-0144-6 |
0.381 |
|
| 2014 |
Bernard JJ, Lou YR, Peng QY, Li T, Vakil PR, Ding N, Laskin JD, Dong Z, Conney AH, Lu YP. Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells. Journal of Carcinogenesis & Mutagenesis. 5: 2157-2518. PMID 25821644 DOI: 10.4172/2157-2518.1000183 |
0.394 |
|
| 2014 |
Wang HQ, Li DL, Lu YJ, Cui XX, Zhou XF, Lin WP, Conney AH, Zhang K, Du ZY, Zheng X. Anticancer activity of Acanthopanax trifoliatus (L) Merr extracts is associated with inhibition of NF-kB activity and decreased Erk1/2 and Akt phosphorylation. Asian Pacific Journal of Cancer Prevention : Apjcp. 15: 9341-6. PMID 25422222 DOI: 10.7314/Apjcp.2014.15.21.9341 |
0.373 |
|
| 2014 |
Huang H, He Y, Cui XX, Goodin S, Wang H, Du ZY, Li D, Zhang K, Tony Kong AN, DiPaola RS, Yang CS, Conney AH, Zheng X. Potent inhibitory effect of δ-tocopherol on prostate cancer cells cultured in vitro and grown as xenograft tumors in vivo. Journal of Agricultural and Food Chemistry. 62: 10752-8. PMID 25322450 DOI: 10.1021/Jf504058F |
0.269 |
|
| 2014 |
Saw CL, Yang AY, Huang MT, Liu Y, Lee JH, Khor TO, Su ZY, Shu L, Lu Y, Conney AH, Kong AN. Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages. Cell & Bioscience. 4: 39. PMID 25228981 DOI: 10.1186/2045-3701-4-39 |
0.294 |
|
| 2014 |
Zhou DY, Ding N, Du ZY, Cui XX, Wang H, Wei XC, Conney AH, Zhang K, Zheng X. Curcumin analogues with high activity for inhibiting human prostate cancer cell growth and androgen receptor activation. Molecular Medicine Reports. 10: 1315-22. PMID 25060817 DOI: 10.3892/Mmr.2014.2380 |
0.382 |
|
| 2014 |
Huang H, Cui XX, Chen S, Goodin S, Liu Y, He Y, Li D, Wang H, Van Doren J, Dipaola RS, Conney AH, Zheng X. Combination of Lipitor and Celebrex inhibits prostate cancer VCaP cells in vitro and in vivo. Anticancer Research. 34: 3357-63. PMID 24982340 |
0.314 |
|
| 2014 |
Ding N, Cui XX, Gao Z, Huang H, Wei X, Du Z, Lin Y, Shih WJ, Rabson AB, Conney AH, Hu C, Zheng X. A triple combination of atorvastatin, celecoxib and tipifarnib strongly inhibits pancreatic cancer cells and xenograft pancreatic tumors. International Journal of Oncology. 44: 2139-45. PMID 24647860 DOI: 10.3892/Ijo.2014.2350 |
0.422 |
|
| 2014 |
Zhou DY, Ding N, Van Doren J, Wei XC, Du ZY, Conney AH, Zhang K, Zheng X. Effects of curcumin analogues for inhibiting human prostate cancer cells and the growth of human PC-3 prostate xenografts in immunodeficient mice. Biological & Pharmaceutical Bulletin. 37: 1029-34. PMID 24647337 DOI: 10.1248/Bpb.B14-00044 |
0.414 |
|
| 2014 |
Su ZY, Zhang C, Lee JH, Shu L, Wu TY, Khor TO, Conney AH, Lu YP, Kong AN. Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane. Cancer Prevention Research (Philadelphia, Pa.). 7: 319-29. PMID 24441674 DOI: 10.1158/1940-6207.Capr-13-0313-T |
0.408 |
|
| 2014 |
Wang H, Cui XX, Goodin S, Ding N, Van Doren J, Du Z, Huang MT, Liu Y, Cheng X, Dipaola RS, Conney AH, Zheng X. Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib. Oncology Reports. 31: 835-41. PMID 24296978 DOI: 10.3892/Or.2013.2885 |
0.375 |
|
| 2014 |
Bernard JJ, Lou YR, Peng QY, Li T, Conney AH, Lu YP. Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Experimental and Molecular Pathology. 96: 126-31. PMID 24184701 DOI: 10.1016/J.Yexmp.2013.10.011 |
0.391 |
|
| 2013 |
Lou Y, Peng Q, Li T, Nolan B, Bernard JJ, Wagner GC, Lin Y, Shih WJ, Conney AH, Lu Y. Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. Nutrition and Cancer. 65: 1002-13. PMID 24070239 DOI: 10.1080/01635581.2013.812224 |
0.446 |
|
| 2013 |
Zhou DY, Zhang K, Conney AH, Ding N, Cui XX, Wang H, Verano M, Zhao SQ, Fan YX, Zheng X, Du ZY. Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells. Chemical & Pharmaceutical Bulletin. 61: 1149-55. PMID 23985704 DOI: 10.1248/Cpb.C13-00507 |
0.388 |
|
| 2013 |
Du ZY, Wei X, Huang MT, Zheng X, Liu Y, Conney AH, Zhang K. Anti-proliferative, anti-inflammatory and antioxidant effects of curcumin analogue A₂. Archives of Pharmacal Research. 36: 1204-10. PMID 23888334 DOI: 10.1007/S12272-013-0216-1 |
0.381 |
|
| 2013 |
Conney AH, Lu YP, Lou YR, Kawasumi M, Nghiem P. Mechanisms of Caffeine-Induced Inhibition of UVB Carcinogenesis. Frontiers in Oncology. 3: 144. PMID 23785666 DOI: 10.3389/Fonc.2013.00144 |
0.441 |
|
| 2013 |
Chang RL, Wood AW, Huang MT, Xie JG, Cui XX, Reuhl KR, Boyd DR, Lin Y, Shih WJ, Balani SK, Yagi H, Jerina DM, Conney AH. Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene. Carcinogenesis. 34: 2184-91. PMID 23671133 DOI: 10.1093/Carcin/Bgt164 |
0.423 |
|
| 2013 |
Wei X, Zhou D, Wang H, Ding N, Cui XX, Wang H, Verano M, Zhang K, Conney AH, Zheng X, DU ZY. Effects of pyridine analogs of curcumin on growth, apoptosis and NF-κB activity in prostate cancer PC-3 cells. Anticancer Research. 33: 1343-50. PMID 23564771 |
0.262 |
|
| 2013 |
Jiang Y, Du Z, Xue G, Chen Q, Lu Y, Zheng X, Conney AH, Zhang K. Synthesis and biological evaluation of unsymmetrical curcumin analogues as tyrosinase inhibitors. Molecules (Basel, Switzerland). 18: 3948-61. PMID 23552906 DOI: 10.3390/Molecules18043948 |
0.381 |
|
| 2013 |
Su ZY, Khor TO, Shu L, Lee JH, Saw CL, Wu TY, Huang Y, Suh N, Yang CS, Conney AH, Wu Q, Kong AN. Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation. Chemical Research in Toxicology. 26: 477-85. PMID 23441843 DOI: 10.1021/Tx300524P |
0.257 |
|
| 2013 |
Conney AH, Lou YR, Nghiem P, Bernard JJ, Wagner GC, Lu YP. Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat. Topics in Current Chemistry. 329: 61-72. PMID 22752580 DOI: 10.1007/128_2012_336 |
0.351 |
|
| 2013 |
Bernard JJ, Lou Y, Peng S, Li T, Nghiem P, Conney AH, Lu Y. Abstract 569: Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Cancer Research. 73: 569-569. DOI: 10.1158/1538-7445.Am2013-569 |
0.41 |
|
| 2013 |
Lee JH, Shu L, Huang M, Conney AH, Kong AT. Abstract 5371: Epigenetic regulation in skin cancer: global DNA methylation profiling in DMBA/TPA induced mice. Cancer Research. 73: 5371-5371. DOI: 10.1158/1538-7445.Am2013-5371 |
0.376 |
|
| 2013 |
Lou Y, Bernard JJ, Peng Q, Li T, Conney AH, Lu Y. Abstract 3689: High fat diet induces the expression of IL-6 and MCP1 exclusively in the rostral portion of the parametrial fat pads in SKH-1 mice. Cancer Research. 73: 3689-3689. DOI: 10.1158/1538-7445.Am2013-3689 |
0.398 |
|
| 2013 |
Su Z, Shu L, Zhang C, Khor TO, Lee JH, Wu T, Conney AH, Kong AT. Abstract 3658: Sulforaphane suppresses 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse epidermal JB6 P+ cell transformation through epigenetic re-activation of Nrf2. Cancer Research. 73: 3658-3658. DOI: 10.1158/1538-7445.Am2013-3658 |
0.432 |
|
| 2013 |
Jia Q, Benjamin PMS, Huang J, Du Z, Zheng X, Zhang K, Conney AH, Wang J. ChemInform Abstract: Synthesis of 3,4-Disubstituted Isoxazoles via Enamine [3 + 2] Cycloaddition. Cheminform. 44: no-no. DOI: 10.1002/CHIN.201318110 |
0.2 |
|
| 2012 |
Goodin S, Stein MN, Shih W, Lu SE, Zheng X, Anand M, Jeyamohan C, Mayer TM, Somer RA, Heath E, Conney A, DiPaola RS. A phase II study of atorvastatin and celecoxib in patients with rising PSA following local therapy for prostate cancer (PC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 89. PMID 27968290 DOI: 10.1200/Jco.2012.30.5_Suppl.89 |
0.28 |
|
| 2012 |
Zheng X, Cui XX, Huang MT, Liu Y, Wagner GC, Lin Y, Shih WJ, Lee MJ, Yang CS, Conney AH. Inhibition of progression of androgen-dependent prostate LNCaP tumors to androgen independence in SCID mice by oral caffeine and voluntary exercise. Nutrition and Cancer. 64: 1029-37. PMID 23061906 DOI: 10.1080/01635581.2012.716899 |
0.428 |
|
| 2012 |
Zheng X, Cui XX, Gao Z, Verano M, Huang MT, Liu Y, Rabson AB, Conney AH. Effects of 12-O-tetradecanoylphorbol-13-acetate in combination with gemcitabine on Panc-1 pancreatic cancer cells cultured in vitro or Panc-1 tumors grown in immunodeficient mice. International Journal of Oncology. 41: 2269-75. PMID 23041978 DOI: 10.3892/Ijo.2012.1651 |
0.442 |
|
| 2012 |
Wei X, DU ZY, Cui XX, Verano M, Mo RQ, Tang ZK, Conney AH, Zheng X, Zhang K. Effects of cyclohexanone analogues of curcumin on growth, apoptosis and NF-κB activity in PC-3 human prostate cancer cells. Oncology Letters. 4: 279-284. PMID 22844370 DOI: 10.3892/Ol.2012.710 |
0.391 |
|
| 2012 |
Lu YP, Lou YR, Bernard JJ, Peng QY, Li T, Lin Y, Shih WJ, Nghiem P, Shapses S, Wagner GC, Conney AH. Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proceedings of the National Academy of Sciences of the United States of America. 109: 9065-70. PMID 22615388 DOI: 10.1073/Pnas.1205810109 |
0.432 |
|
| 2012 |
Wei X, Du ZY, Zheng X, Cui XX, Conney AH, Zhang K. Synthesis and evaluation of curcumin-related compounds for anticancer activity. European Journal of Medicinal Chemistry. 53: 235-45. PMID 22551677 DOI: 10.1016/J.Ejmech.2012.04.005 |
0.365 |
|
| 2012 |
Conney AH, Reidenberg MM. Cigarette smoking, coffee drinking, and ingestion of charcoal-broiled beef as potential modifiers of drug therapy and confounders of clinical trials. The Journal of Pharmacology and Experimental Therapeutics. 342: 9-14. PMID 22514335 DOI: 10.1124/Jpet.112.193193 |
0.37 |
|
| 2012 |
Du Z, Qin B, Sun C, Liu Y, Zheng X, Zhang K, Conney AH, Zeng H. Folding-promoted TBAX-mediated selective demethylation of methoxybenzene-based macrocyclic aromatic pentamers. Organic & Biomolecular Chemistry. 10: 4164-71. PMID 22456627 DOI: 10.1039/C2Ob25160D |
0.341 |
|
| 2012 |
Lu Y, Lou Y, Peng Q, Li T, Nolan B, Lin Y, Shih WJ, Wagner GC, Conney AH. Abstract 4286: Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases cytokines associated with inflammation in UVB-treated mice Cancer Research. 72: 4286-4286. DOI: 10.1158/1538-7445.Am2012-4286 |
0.46 |
|
| 2012 |
Du Z, Wang J, Jia Q, Benjamin P, Huang J, Zheng X, Zhang K, Conney A. Synthesis of 3,4-Disubsituted Isoxazoles via Enamine [3+2] Cycloaddition Synlett. 24: 79-84. DOI: 10.1055/S-0032-1317923 |
0.325 |
|
| 2011 |
Zheng X, Cui XX, Khor TO, Huang Y, Dipaola RS, Goodin S, Lee MJ, Yang CS, Kong AN, Conney AH. Inhibitory Effect of a γ-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice. Cancers. 3: 3762-72. PMID 24213110 DOI: 10.3390/Cancers3043762 |
0.338 |
|
| 2011 |
Conney AH. Donald M. Jerina (1940–2011). Carcinogenesis. 32: 1403. PMID 21998880 DOI: 10.1093/Carcin/Bgr185 |
0.292 |
|
| 2011 |
Kawasumi M, Lemos B, Bradner JE, Thibodeau R, Kim YS, Schmidt M, Higgins E, Koo SW, Angle-Zahn A, Chen A, Levine D, Nguyen L, Heffernan TP, Longo I, Mandinova A, ... ... Conney AH, et al. Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase. Proceedings of the National Academy of Sciences of the United States of America. 108: 13716-21. PMID 21844338 DOI: 10.1073/Pnas.1111378108 |
0.43 |
|
| 2011 |
Zheng X, Cui XX, Gao Z, Zhao Y, Shi Y, Huang MT, Liu Y, Wagner GC, Lin Y, Shih WJ, Rao CV, Yang CS, Conney AH. Inhibitory effect of dietary atorvastatin and celecoxib together with voluntary running wheel exercise on the progression of androgen-dependent LNCaP prostate tumors to androgen independence. Experimental and Therapeutic Medicine. 2: 221-228. PMID 21660218 DOI: 10.3892/Etm.2011.203 |
0.426 |
|
| 2011 |
Saw CL, Huang MT, Liu Y, Khor TO, Conney AH, Kong AN. Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane. Molecular Carcinogenesis. 50: 479-86. PMID 21557329 DOI: 10.1002/Mc.20725 |
0.412 |
|
| 2011 |
Lou YR, Peng QY, Li T, Medvecky CM, Lin Y, Shih WJ, Conney AH, Shapses S, Wagner GC, Lu YP. Effects of high-fat diets rich in either omega-3 or omega-6 fatty acids on UVB-induced skin carcinogenesis in SKH-1 mice. Carcinogenesis. 32: 1078-84. PMID 21525235 DOI: 10.1093/Carcin/Bgr074 |
0.437 |
|
| 2011 |
Lu YP, Lou YR, Peng QY, Nghiem P, Conney AH. Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice. Cancer Prevention Research (Philadelphia, Pa.). 4: 1118-25. PMID 21505179 DOI: 10.1158/1940-6207.Capr-11-0116 |
0.443 |
|
| 2011 |
So JY, Lee HJ, Smolarek AK, Paul S, Wang CX, Maehr H, Uskokovic M, Zheng X, Conney AH, Cai L, Liu F, Suh N. A novel Gemini vitamin D analog represses the expression of a stem cell marker CD44 in breast cancer. Molecular Pharmacology. 79: 360-7. PMID 21115634 DOI: 10.1124/Mol.110.068403 |
0.266 |
|
| 2011 |
Lu Y, Lou Y, Peng Q, Li T, Zhou S, Nghiem P, Conney AH. Abstract 1815: Stimulation of apoptosis by caffeine or exercise is associated with an increase in thymine dimer formation in the epidermis of UVB-treated SKH-1 mice Cancer Research. 71: 1815-1815. DOI: 10.1158/1538-7445.Am2011-1815 |
0.443 |
|
| 2010 |
Paul S, Mizuno CS, Lee HJ, Zheng X, Chajkowisk S, Rimoldi JM, Conney A, Suh N, Rimando AM. In vitro and in vivo studies on stilbene analogs as potential treatment agents for colon cancer. European Journal of Medicinal Chemistry. 45: 3702-8. PMID 20627379 DOI: 10.1016/J.Ejmech.2010.05.019 |
0.448 |
|
| 2010 |
Zhu BT, Wu KY, Wang P, Cai MX, Conney AH. O-methylation of catechol estrogens by human placental catechol-o-methyltransferase: interindividual differences in sensitivity to heat inactivation and to inhibition by dietary polyphenols. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1892-9. PMID 20606002 DOI: 10.1124/dmd.110.033548 |
0.283 |
|
| 2010 |
Zheng X, Cui XX, Gao Z, Zhao Y, Lin Y, Shih WJ, Huang MT, Liu Y, Rabson A, Reddy B, Yang CS, Conney AH. Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence. Cancer Prevention Research (Philadelphia, Pa.). 3: 114-24. PMID 20051379 DOI: 10.1158/1940-6207.Capr-09-0059 |
0.336 |
|
| 2010 |
Zheng X, Cui X, Gao Z, Shi Y, Rabson A, Conney AH. Abstract 5423: Effects of atorvastatin, celecoxib and tipifarnib alone or in combination on the growth of pancreatic cancer in Panc-1 cells cultured in vitro or Panc-1 tumors grown in immunodeficient mice Cancer Research. 70: 5423-5423. DOI: 10.1158/1538-7445.Am10-5423 |
0.43 |
|
| 2010 |
Lu Y, Lou Y, Peng Q, Conney AH. Abstract 1217: Effects of topical applications of caffeine on phospho-Chk1 (Ser317), mitotic cells with cyclin B1 and mitotic cells with caspase 3 in skin tumors from UVB pretreated SKH-1 mice Cancer Research. 70: 1217-1217. DOI: 10.1158/1538-7445.Am10-1217 |
0.428 |
|
| 2010 |
Gonzalez FJ, Conney AH. Harry V. Gelboin, 1929-2010 Carcinogenesis. 31: 1308-1309. DOI: 10.1093/Carcin/Bgq093 |
0.32 |
|
| 2009 |
Rao CV, Steele VE, Stoner GD, Conney AH. Bandaru s. Reddy: in memoriam (1930-2009). Cancer Prevention Research (Philadelphia, Pa.). 2: 912-3. PMID 19805402 DOI: 10.1158/1940-6207.Capr-09-0180 |
0.325 |
|
| 2009 |
Heffernan TP, Kawasumi M, Blasina A, Anderes K, Conney AH, Nghiem P. ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine. The Journal of Investigative Dermatology. 129: 1805-15. PMID 19242509 DOI: 10.1038/Jid.2008.435 |
0.413 |
|
| 2009 |
Lu YP, Lou YR, Xie JG, Peng Q, Shih WJ, Lin Y, Conney AH. Tumorigenic effect of some commonly used moisturizing creams when applied topically to UVB-pretreated high-risk mice. The Journal of Investigative Dermatology. 129: 468-75. PMID 18704106 DOI: 10.1038/Jid.2008.241 |
0.414 |
|
| 2009 |
Conney AH, Lu Y, Shih WJ. Response to Jewell Journal of Investigative Dermatology. 129: 2318-2321. DOI: 10.1038/Jid.2009.160 |
0.296 |
|
| 2009 |
Conney AH, Lu Y, Shih WJ. Response to Ellefson Journal of Investigative Dermatology. 129: 514-515. DOI: 10.1038/Jid.2008.401 |
0.296 |
|
| 2009 |
Conney AH, Lu Y, Shih WJ. Response to Staeb et al. Journal of Investigative Dermatology. 129: 517-518. DOI: 10.1038/Jid.2008.400 |
0.291 |
|
| 2008 |
Lee HJ, Paul S, Atalla N, Thomas PE, Lin X, Yang I, Buckley B, Lu G, Zheng X, Lou YR, Conney AH, Maehr H, Adorini L, Uskokovic M, Suh N. Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity. Cancer Prevention Research (Philadelphia, Pa.). 1: 476-84. PMID 19138995 DOI: 10.1158/1940-6207.Capr-08-0084 |
0.389 |
|
| 2008 |
Zheng X, Cui XX, Huang MT, Liu Y, Shih WJ, Lin Y, Lu YP, Wagner GC, Conney AH. Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice. Oncology Reports. 19: 1583-8. PMID 18497969 DOI: 10.3892/Or.19.6.1583 |
0.309 |
|
| 2008 |
Lu YP, Lou YR, Peng QY, Xie JG, Nghiem P, Conney AH. Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice. Cancer Research. 68: 2523-9. PMID 18381462 DOI: 10.1158/0008-5472.Can-07-5955 |
0.452 |
|
| 2008 |
Mesia-Vela S, Sanchez RI, Roberts KG, Reuhl KR, Conney AH, Kauffman FC. Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats. Toxicology. 246: 63-72. PMID 18280627 DOI: 10.1016/J.Tox.2007.12.025 |
0.443 |
|
| 2008 |
Rogozin EA, Lee KW, Kang NJ, Yu H, Nomura M, Miyamoto K, Conney AH, Bode AM, Dong Z. Inhibitory effects of caffeine analogues on neoplastic transformation: structure-activity relationship. Carcinogenesis. 29: 1228-34. PMID 18195054 DOI: 10.1093/Carcin/Bgn016 |
0.427 |
|
| 2008 |
Conney AH, Kramata P, Lou YR, Lu YP. Effect of caffeine on UVB-induced carcinogenesis, apoptosis, and the elimination of UVB-induced patches of p53 mutant epidermal cells in SKH-1 mice. Photochemistry and Photobiology. 84: 330-8. PMID 18179623 DOI: 10.1111/J.1751-1097.2007.00263.X |
0.463 |
|
| 2008 |
Zheng X, Chang RL, Cui XX, Avila G, Huang MT, Liu Y, Kong AN, Rabson AB, Conney AH. Inhibition of NF-kappaB by (E)3-[(4-methylphenyl)-sulfonyl]-2-propenenitrile (BAY11-7082; BAY) is associated with enhanced 12-O-tetradecanoylphorbol-13-acetate-induced growth suppression and apoptosis in human prostate cancer PC-3 cells. International Journal of Oncology. 32: 257-64. PMID 18097566 |
0.348 |
|
| 2008 |
Zhu BT, Gallo MA, Burger CW, Meeker RJ, Cai MX, Xu S, Conney AH. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin administration and high-fat diet on the body weight and hepatic estrogen metabolism in female C3H/HeN mice. Toxicology and Applied Pharmacology. 226: 107-18. PMID 17945325 DOI: 10.1016/J.Taap.2007.08.018 |
0.686 |
|
| 2007 |
Zheng X, Cui XX, Avila GE, Huang MT, Liu Y, Patel J, Kong AN, Paulino R, Shih WJ, Lin Y, Rabson AB, Reddy BS, Conney AH. Atorvastatin and celecoxib inhibit prostate PC-3 tumors in immunodeficient mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5480-7. PMID 17875778 DOI: 10.1158/1078-0432.Ccr-07-0242 |
0.402 |
|
| 2007 |
Lu YP, Nolan B, Lou YR, Peng QY, Wagner GC, Conney AH. Voluntary exercise together with oral caffeine markedly stimulates UVB light-induced apoptosis and decreases tissue fat in SKH-1 mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 12936-41. PMID 17664435 DOI: 10.1073/Pnas.0705839104 |
0.311 |
|
| 2007 |
Conney AH, Zhou S, Lee MJ, Xie JG, Yang CS, Lou YR, Lu Y. Stimulatory effect of oral administration of tea, coffee or caffeine on UVB-induced apoptosis in the epidermis of SKH-1 mice. Toxicology and Applied Pharmacology. 224: 209-13. PMID 17188726 DOI: 10.1016/J.Taap.2006.11.001 |
0.453 |
|
| 2007 |
Lu YP, Lou YR, Xie JG, Peng QY, Zhou S, Lin Y, Shih WJ, Conney AH. Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice. Carcinogenesis. 28: 199-206. PMID 16864596 DOI: 10.1093/Carcin/Bgl112 |
0.445 |
|
| 2007 |
Kuntzman R, Conney A. Dr John J Burns, 1920–2007 Neuropsychopharmacology. 33: 458-459. DOI: 10.1038/Sj.Npp.1301582 |
0.313 |
|
| 2006 |
Lu YP, Lou YR, Nolan B, Peng QY, Xie JG, Wagner GC, Conney AH. Stimulatory effect of voluntary exercise or fat removal (partial lipectomy) on apoptosis in the skin of UVB light-irradiated mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 16301-6. PMID 17060638 DOI: 10.1073/Pnas.0607789103 |
0.329 |
|
| 2006 |
Xu C, Huang MT, Shen G, Yuan X, Lin W, Khor TO, Conney AH, Kong AN. Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2. Cancer Research. 66: 8293-6. PMID 16912211 DOI: 10.1158/0008-5472.Can-06-0300 |
0.327 |
|
| 2006 |
Zheng X, Chang RL, Cui XX, Avila GE, Hebbar V, Garzotto M, Shih WJ, Lin Y, Lu SE, Rabson AB, Kong AN, Conney AH. Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate Cancer LNCaP cells cultured in vitro or grown as xenograft tumors in immunodeficient mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3444-51. PMID 16740769 DOI: 10.1158/1078-0432.Ccr-05-2823 |
0.426 |
|
| 2006 |
Michna L, Wagner GC, Lou YR, Xie JG, Peng QY, Lin Y, Carlson K, Shih WJ, Conney AH, Lu YP. Inhibitory effects of voluntary running wheel exercise on UVB-induced skin carcinogenesis in SKH-1 mice. Carcinogenesis. 27: 2108-15. PMID 16699173 DOI: 10.1093/Carcin/Bgl057 |
0.416 |
|
| 2006 |
Khor TO, Keum YS, Lin W, Kim JH, Hu R, Shen G, Xu C, Gopalakrishnan A, Reddy B, Zheng X, Conney AH, Kong AN. Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice. Cancer Research. 66: 613-21. PMID 16423986 DOI: 10.1158/0008-5472.Can-05-2708 |
0.413 |
|
| 2006 |
Mesia-Vela S, Sanchez RI, Reuhl KR, Conney AH, Kauffman FC. Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat. The Journal of Pharmacology and Experimental Therapeutics. 317: 590-7. PMID 16421288 DOI: 10.1124/Jpet.105.096867 |
0.29 |
|
| 2006 |
Kim JH, Xu C, Keum YS, Reddy B, Conney A, Kong AN. Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin. Carcinogenesis. 27: 475-82. PMID 16299382 DOI: 10.1093/Carcin/Bgi272 |
0.395 |
|
| 2006 |
Schaar D, Goodell L, Aisner J, Cui XX, Han ZT, Chang R, Martin J, Grospe S, Dudek L, Riley J, Manago J, Lin Y, Rubin EH, Conney A, Strair RK. A phase I clinical trial of 12- O-tetradecanoylphorbol-13-acetate for patients with relapsed/refractory malignancies. Cancer Chemotherapy and Pharmacology. 57: 789-95. PMID 16231182 DOI: 10.1007/S00280-005-0125-1 |
0.382 |
|
| 2005 |
Hansson A, Marín YE, Suh J, Rabson AB, Chen S, Huberman E, Chang RL, Conney AH, Zheng X. Enhancement of TPA-induced growth inhibition and apoptosis in myeloid leukemia cells by BAY 11-7082, an NF-kappaB inhibitor. International Journal of Oncology. 27: 941-8. PMID 16142309 |
0.299 |
|
| 2005 |
Avila GE, Zheng X, Cui XX, Ryan AD, Hansson A, Suh J, Rabson AB, Chang RL, Shih WJ, Lin Y, Crowell P, Lu YP, Lou YR, Conney AH. Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice. The Journal of Pharmacology and Experimental Therapeutics. 315: 170-87. PMID 15976015 DOI: 10.1124/Jpet.105.087585 |
0.355 |
|
| 2005 |
Kramata P, Lu YP, Lou YR, Cohen JL, Olcha M, Liu S, Conney AH. Effect of administration of caffeine or green tea on the mutation profile in the p53 gene in early mutant p53-positive patches of epidermal cells induced by chronic UVB-irradiation of hairless SKH-1 mice. Carcinogenesis. 26: 1965-74. PMID 15975959 DOI: 10.1093/Carcin/Bgi162 |
0.411 |
|
| 2005 |
Kramata P, Lu YP, Lou YR, Singh RN, Kwon SM, Conney AH. Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice. Cancer Research. 65: 3577-85. PMID 15867351 DOI: 10.1158/0008-5472.CAN-04-4537 |
0.288 |
|
| 2005 |
Lu YP, Lou YR, Liao J, Xie JG, Peng QY, Yang CS, Conney AH. Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice. Carcinogenesis. 26: 1465-72. PMID 15817611 DOI: 10.1093/Carcin/Bgi086 |
0.426 |
|
| 2005 |
Zheng X, Ryan A, Patel N, Klemons S, Hansson A, Shih WJ, Lin Y, Huberman E, Chang RL, Conney AH. Synergistic stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate and capsaicin on macrophage differentiation in HL-60 and HL-525 human myeloid leukemia cells. International Journal of Oncology. 26: 441-8. PMID 15645129 |
0.301 |
|
| 2004 |
Turan VK, Sanchez RI, Li JJ, Li SA, Reuhl KR, Thomas PE, Conney AH, Gallo MA, Kauffman FC, Mesia-Vela S. The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone. The Journal of Endocrinology. 183: 91-9. PMID 15525577 DOI: 10.1677/Joe.1.05802 |
0.286 |
|
| 2004 |
Wogan GN, Hecht SS, Felton JS, Conney AH, Loeb LA. Environmental and chemical carcinogenesis. Seminars in Cancer Biology. 14: 473-86. PMID 15489140 DOI: 10.1016/J.Semcancer.2004.06.010 |
0.421 |
|
| 2004 |
Huang MT, Xie JG, Lin CB, Kizoulis M, Seiberg M, Shapiro S, Conney AH. Inhibitory effect of topical applications of nondenatured soymilk on the formation and growth of UVB-induced skin tumors. Oncology Research. 14: 387-97. PMID 15301430 DOI: 10.3727/0965040041292350 |
0.42 |
|
| 2004 |
Lu YP, Lou YR, Peng QY, Xie JG, Conney AH. Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice. Cancer Research. 64: 5020-7. PMID 15256477 DOI: 10.1158/0008-5472.Can-04-0760 |
0.424 |
|
| 2004 |
Mesia-Vela S, Sanchez RI, Reuhl KR, Conney AH, Kauffman FC. Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats. Toxicology. 200: 103-11. PMID 15212807 DOI: 10.1016/J.Tox.2004.03.009 |
0.431 |
|
| 2004 |
Nagai M, Conney AH, Zhu BT. Strong inhibitory effects of common tea catechins and bioflavonoids on the O-methylation of catechol estrogens catalyzed by human liver cytosolic catechol-O-methyltransferase. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 497-504. PMID 15100171 DOI: 10.1124/dmd.32.5.497 |
0.266 |
|
| 2004 |
Zheng X, Chang RL, Cui XX, Avila GE, Lee S, Lu YP, Lou YR, Shih WJ, Lin Y, Reuhl K, Newmark H, Rabson A, Conney AH. Inhibitory effect of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans-retinoic acid on the growth of LNCaP prostate tumors in immunodeficient mice. Cancer Research. 64: 1811-20. PMID 14996744 DOI: 10.1158/0008-5472.CAN-03-2848 |
0.344 |
|
| 2004 |
Conney AH. Tailoring cancer chemoprevention regimens to the individual. Journal of Cellular Biochemistry. 91: 277-86. PMID 14743388 DOI: 10.1002/Jcb.20001 |
0.344 |
|
| 2003 |
Ju J, Liu Y, Hong J, Huang MT, Conney AH, Yang CS. Effects of green tea and high-fat diet on arachidonic acid metabolism and aberrant crypt foci formation in an azoxymethane-induced colon carcinogenesis mouse model. Nutrition and Cancer. 46: 172-8. PMID 14690793 DOI: 10.1207/S15327914Nc4602_10 |
0.423 |
|
| 2003 |
Conney AH. Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: the Seventh DeWitt S. Goodman Lecture. Cancer Research. 63: 7005-31. PMID 14612489 |
0.265 |
|
| 2003 |
Lee AJ, Conney AH, Zhu BT. Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol. Cancer Research. 63: 6532-6. PMID 14559847 |
0.264 |
|
| 2003 |
Lee AJ, Cai MX, Thomas PE, Conney AH, Zhu BT. Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. Endocrinology. 144: 3382-98. PMID 12865317 DOI: 10.1210/En.2003-0192 |
0.378 |
|
| 2003 |
Michna L, Lu YP, Lou YR, Wagner GC, Conney AH. Stimulatory effect of oral administration of green tea and caffeine on locomotor activity in SKH-1 mice. Life Sciences. 73: 1383-92. PMID 12850499 DOI: 10.1016/S0024-3205(03)00468-5 |
0.435 |
|
| 2003 |
Conney AH. Induction of drug-metabolizing enzymes: a path to the discovery of multiple cytochromes P450. Annual Review of Pharmacology and Toxicology. 43: 1-30. PMID 12540740 DOI: 10.1146/Annurev.Pharmtox.43.100901.135754 |
0.384 |
|
| 2002 |
Conney AH, Lu YP, Lou YR, Huang MT. Inhibitory effects of tea and caffeine on UV-induced carcinogenesis: relationship to enhanced apoptosis and decreased tissue fat. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). 11: S28-36. PMID 12570332 |
0.357 |
|
| 2002 |
Cui XX, Chang RL, Zheng X, Woodward D, Strair R, Conney AH. A sensitive bioassay for measuring blood levels of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients: preliminary pharmacokinetic studies. Oncology Research. 13: 169-74. PMID 12549626 |
0.247 |
|
| 2002 |
Blagosklonny MV, Conney AH. Combining phorbol ester (PMA) with UCN-01: fueling fire with water. Cell Cycle (Georgetown, Tex.). 1: 258-9. PMID 12429943 DOI: 10.4161/cc.1.4.134 |
0.185 |
|
| 2002 |
Lu YP, Lou YR, Li XH, Xie JG, Lin Y, Shih WJ, Conney AH. Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin. Oncology Research. 13: 61-70. PMID 12392153 |
0.334 |
|
| 2002 |
Zheng X, Ravatn R, Lin Y, Shih WC, Rabson A, Strair R, Huberman E, Conney A, Chin KV. Gene expression of TPA induced differentiation in HL-60 cells by DNA microarray analysis. Nucleic Acids Research. 30: 4489-99. PMID 12384596 DOI: 10.1093/Nar/Gkf580 |
0.38 |
|
| 2002 |
Lu YP, Lou YR, Xie JG, Peng QY, Liao J, Yang CS, Huang MT, Conney AH. Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 12455-60. PMID 12205293 DOI: 10.1073/Pnas.182429899 |
0.435 |
|
| 2002 |
Strair RK, Schaar D, Goodell L, Aisner J, Chin KV, Eid J, Senzon R, Cui XX, Han ZT, Knox B, Rabson AB, Chang R, Conney A. Administration of a phorbol ester to patients with hematological malignancies: preliminary results from a phase I clinical trial of 12-O-tetradecanoylphorbol-13-acetate. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2512-8. PMID 12171877 |
0.276 |
|
| 2002 |
Mesia-Vela S, Sanchez RI, Li JJ, Li SA, Conney AH, Kauffman FC. Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. Carcinogenesis. 23: 1369-72. PMID 12151356 DOI: 10.1093/Carcin/23.8.1369 |
0.292 |
|
| 2002 |
Zhu BT, Cai MX, Spink DC, Hussain MM, Busch CM, Ranzini AC, Lai YL, Lambert GH, Thomas PE, Conney AH. Stimulatory effect of cigarette smoking on the 15 alpha-hydroxylation of estradiol by human term placenta. Clinical Pharmacology and Therapeutics. 71: 311-24. PMID 12011817 DOI: 10.1067/Mcp.2002.122500 |
0.234 |
|
| 2002 |
Xu S, Zhu BT, Conney AH. Effect of clofibrate administration on the esterification and deesterification of steroid hormones by liver and extrahepatic tissues in rats. Biochemical Pharmacology. 63: 985-92. PMID 11911851 DOI: 10.1016/S0006-2952(01)00921-2 |
0.674 |
|
| 2002 |
Lee AJ, Mills LH, Kosh JW, Conney AH, Zhu BT. NADPH-dependent metabolism of estrone by human liver microsomes. The Journal of Pharmacology and Experimental Therapeutics. 300: 838-49. PMID 11861789 |
0.3 |
|
| 2001 |
Xu S, Zhu BT, Turan V, Rusyn I, Thurman R, Peters JM, Gonzalez FJ, Conney AH. PPARα-Dependent Induction of Liver Microsomal Esterification of Estradiol and Testosterone by a Prototypical Peroxisome Proliferator. Endocrinology. 142: 3554-3557. PMID 28201440 DOI: 10.1210/endo.142.8.8330 |
0.696 |
|
| 2001 |
Zhu BT, Patel UK, Cai MX, Lee AJ, Conney AH. Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 31: 879-90. PMID 11780762 DOI: 10.1080/00498250110079798 |
0.273 |
|
| 2001 |
Conney AH, Chang RL, Cui XX, Schiltz M, Yagi H, Jerina DM, Wei SJ. Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons. Advances in Experimental Medicine and Biology. 500: 697-707. PMID 11765016 DOI: 10.1007/978-1-4615-0667-6_102 |
0.736 |
|
| 2001 |
Xu S, Zhu BT, Turan V, Rusyn I, Thurman R, Peters JM, Gonzalez FJ, Conney AH. PPARα-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator Endocrinology. 142: 3554-3557. PMID 11459802 DOI: 10.1210/Endo.142.8.8330 |
0.74 |
|
| 2001 |
Kumar S, Chang RL, Wood AW, Xie JG, Huang MT, Cui XX, Kole PL, Sikka HC, Balani SK, Conney AH, Jerina DM. Tumorigenicity of racemic and optically pure bay region diol epoxides and other derivatives of the nitrogen heterocycle dibenz[a,h]acridine on mouse skin. Carcinogenesis. 22: 951-5. PMID 11375904 DOI: 10.1093/Carcin/22.6.951 |
0.396 |
|
| 2001 |
Xu S, Zhu BT, Cai MX, Conney AH. Stimulatory effect of clofibrate on the action of estradiol in the mammary gland but not in the uterus of rats. The Journal of Pharmacology and Experimental Therapeutics. 297: 50-6. PMID 11259527 |
0.654 |
|
| 2001 |
Xu S, Zhu BT, Conney AH. Stimulatory effect of clofibrate and gemfibrozil administration on the formation of fatty acid esters of estradiol by rat liver microsomes. The Journal of Pharmacology and Experimental Therapeutics. 296: 188-97. PMID 11123380 |
0.655 |
|
| 2001 |
Zheng X, Chang R, Cui X, Kelly K, Shih W, Lin Y, Strair R, Suh J, Han Z, Rabson A, Conney A. Synergistic Effects of Clinically Achievable Concentrations of 12-O Tetradecanoylphorbol-13-acetate in Combination With all-trans Retinoic Acid, 1α,25-Dihydroxyvitamin D3, and Sodium Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 12: 419-427. DOI: 10.3727/096504001108747873 |
0.385 |
|
| 2000 |
Chang RL, Wood AW, Kumar S, Lehr RE, Shirai N, Jerina DM, Conney AH. Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice. Carcinogenesis. 21: 1997-2003. PMID 11062160 DOI: 10.1093/Carcin/21.11.1997 |
0.428 |
|
| 2000 |
Zhu BT, Kosh JW, Fu J, Cai MX, Xu S, Conney AH. Strong inhibition of estrone-3-sulfatase activity by pregnenolone 16alpha-carbonitrile but not by several analogs lacking a 16alpha-nitrile group. Steroids. 65: 521-7. PMID 10978731 DOI: 10.1016/S0039-128X(00)00129-X |
0.674 |
|
| 1999 |
Schiltz M, Cui XX, Lu YP, Yagi H, Jerina DM, Zdzienicka MZ, Chang RL, Conney AH, Wei SJ. Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells. Carcinogenesis. 20: 2279-86. PMID 10590220 DOI: 10.1093/Carcin/20.12.2279 |
0.736 |
|
| 1999 |
Wei SJ, Chang RL, Merkler KA, Gwynne M, Cui XX, Murthy B, Huang MT, Xie JG, Lu YP, Lou YR, Jerina DM, Conney AH. Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene. Carcinogenesis. 20: 1689-96. PMID 10469612 DOI: 10.1093/Carcin/20.9.1689 |
0.41 |
|
| 1999 |
Lou YR, Lu YP, Xie JG, Huang MT, Conney AH. Effects of oral administration of tea, decaffeinated tea, and caffeine on the formation and growth of tumors in high-risk SKH-1 mice previously treated with ultraviolet B light. Nutrition and Cancer. 33: 146-53. PMID 10368809 DOI: 10.1207/S15327914Nc330205 |
0.427 |
|
| 1999 |
Conney AH, Lu Y, Lou Y, Xie J, Huang M. Inhibitory effect of green and black tea on tumor growth. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 220: 229-33. PMID 10202394 DOI: 10.1046/J.1525-1373.1999.D01-39.X |
0.407 |
|
| 1999 |
Wei SJ, Chang RL, Wong CQ, Cui XX, Dandamudi N, Lu YP, Merkler KA, Sayer JM, Conney AH, Jerina DM. The ratio of deoxyadenosine to deoxyguanosine adducts formed by (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in purified calf thymus DNA and DNA in V-79 cells is independent of dose. International Journal of Oncology. 14: 509-13. PMID 10024684 DOI: 10.3892/Ijo.14.3.509 |
0.411 |
|
| 1998 |
EVANS C, CONNEY AH, TROUSOF N, BURNS JJ. Metabolism of D-galactose to D-glucuronic acid, L-gulonic acid and L-ascorbic acid in normal and barbital-treated rats. Biochimica Et Biophysica Acta. 41: 9-14. PMID 13820966 DOI: 10.1016/0006-3002(60)90362-0 |
0.241 |
|
| 1998 |
CONNEY AH, GILLETTE JR, INSCOE JK, TRAMS ER, POSNER HS. Induced synthesis of liver microsomal enzymes which metabolize foreign compounds. Science (New York, N.Y.). 130: 1478-9. PMID 13811550 DOI: 10.1126/Science.130.3387.1478 |
0.313 |
|
| 1998 |
CONNEY AH, BURNS JJ. Biochemical pharmacological considerations of zoxazolamine and chlorzoxazone metabolism. Annals of the New York Academy of Sciences. 86: 167-77. PMID 13811546 DOI: 10.1111/j.1749-6632.1960.tb42797.x |
0.259 |
|
| 1998 |
BURNS JJ, CONNEY AH. Water-soluble vitamins, Part I. (Ascorbic acid, nicotinic acid, vitamin B6, biotin, inositol). Annual Review of Biochemistry. 29: 413-36. PMID 13806254 DOI: 10.1146/ANNUREV.BI.29.070160.002213 |
0.219 |
|
| 1998 |
CONNEY AH, GARREN L. Contrasting effects of thyroxin on zoxazolamine and hexobarbital metabolism. Biochemical Pharmacology. 6: 257-62. PMID 13695067 DOI: 10.1016/0006-2952(61)90139-3 |
0.27 |
|
| 1998 |
CONNEY AH, BRAY GA, EVANS C, BURNS JJ. Metabolic interactions between L-ascorbic acid and drugs. Annals of the New York Academy of Sciences. 92: 115-27. PMID 13695066 DOI: 10.1111/j.1749-6632.1961.tb46111.x |
0.246 |
|
| 1998 |
Zhu BT, Loder DP, Cai MX, Ho CT, Huang MT, Conney AH. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis. 19: 1821-7. PMID 9806165 DOI: 10.1093/CARCIN/19.10.1821 |
0.34 |
|
| 1998 |
Liu Q, Wang Y, Crist KA, Wang ZY, Lou YR, Huang MT, Conney AH, You M. Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors Carcinogenesis. 19: 1257-1262. PMID 9683186 DOI: 10.1093/Carcin/19.7.1257 |
0.328 |
|
| 1998 |
Zhu BT, Taneja N, Loder DP, Balentine DA, Conney AH. Effects of tea polyphenols and flavonoids on liver microsomal glucuronidation of estradiol and estrone. The Journal of Steroid Biochemistry and Molecular Biology. 64: 207-15. PMID 9605416 DOI: 10.1016/S0960-0760(97)00163-5 |
0.436 |
|
| 1998 |
Zhu BT, Fu JH, Xu S, Kauffman FC, Conney AH. Different biochemical properties of nuclear and microsomal estrone-3-sulfatases: Evidence for the presence of a nuclear isozyme Biochemical and Biophysical Research Communications. 246: 45-49. PMID 9600065 DOI: 10.1006/Bbrc.1998.8568 |
0.657 |
|
| 1998 |
Han ZT, Tong YK, He LM, Zhang Y, Sun JZ, Wang TY, Zhang H, Cui YL, Newmark HL, Conney AH, Chang RL. 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs. Proceedings of the National Academy of Sciences of the United States of America. 95: 5362-5. PMID 9560281 DOI: 10.1073/PNAS.95.9.5362 |
0.254 |
|
| 1998 |
Han ZT, Zhu XX, Yang RY, Sun JZ, Tian GF, Liu XJ, Cao GS, Newmark HL, Conney AH, Chang RL. Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity. Proceedings of the National Academy of Sciences of the United States of America. 95: 5357-61. PMID 9560280 DOI: 10.1073/PNAS.95.9.5357 |
0.237 |
|
| 1998 |
Zhu BT, Conney AH. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis. 19: 1-27. PMID 9472688 DOI: 10.1093/Carcin/19.1.1 |
0.376 |
|
| 1997 |
Lu YP, Lou YR, Xie JG, Yen P, Huang MT, Conney AH. Inhibitory effect of black tea on the growth of established skin tumors in mice: effects on tumor size, apoptosis, mitosis and bromodeoxyuridine incorporation into DNA. Carcinogenesis. 18: 2163-9. PMID 9395217 DOI: 10.1093/Carcin/18.11.2163 |
0.431 |
|
| 1997 |
Conney AH, Lou YR, Xie JG, Osawa T, Newmark HL, Liu Y, Chang RL, Huang MT. Some perspectives on dietary inhibition of carcinogenesis: studies with curcumin and tea. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 216: 234-45. PMID 9349692 DOI: 10.3181/00379727-216-44173 |
0.35 |
|
| 1997 |
Huang MT, Ma W, Yen P, Xie JG, Han J, Frenkel K, Grunberger D, Conney AH. Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis. Carcinogenesis. 18: 83-8. PMID 9054592 DOI: 10.1093/Carcin/18.1.83 |
0.346 |
|
| 1996 |
CONNEY AH, SCHNEIDMAN K, JACOBSON M, KUNTZMAN R. DRUG-INDUCED CHANGES IN STEROID METABOLISM. Annals of the New York Academy of Sciences. 123: 98-109. PMID 14329223 DOI: 10.1111/J.1749-6632.1965.TB12248.X |
0.271 |
|
| 1996 |
BURNS JJ, CUCINELL SA, KOSTER R, CONNEY AH. APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES. Annals of the New York Academy of Sciences. 123: 273-86. PMID 14329210 DOI: 10.1111/J.1749-6632.1965.TB12268.X |
0.245 |
|
| 1996 |
CUCINELL SA, CONNEY AH, SANSUR M, BURNS JJ. DRUG INTERACTIONS IN MAN. I. LOWERING EFFECT OF PHENOBARBITAL ON PLASMA LEVELS OF BISHYDROXYCOUMARIN (DICUMAROL) AND DIPHENYLHYDANTOIN (DILANTIN). Clinical Pharmacology and Therapeutics. 6: 420-9. PMID 14314964 DOI: 10.1002/cpt196564420 |
0.226 |
|
| 1996 |
CONNEY AH, BURNS JJ. INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS. Advances in Enzyme Regulation. 1: 189-214. PMID 14190354 DOI: 10.1016/0065-2571(63)90018-9 |
0.29 |
|
| 1996 |
Zhu BT, Suchar LA, Huang MT, Conney AH. Similarities and differences in the glucuronidation of estradiol and estrone by UDP-glucuronosyltransferase in liver microsomes from male and female rats. Biochemical Pharmacology. 51: 1195-202. PMID 8645343 DOI: 10.1016/0006-2952(96)00062-7 |
0.396 |
|
| 1996 |
Huang MT, Ma W, Yen P, Xie JG, Han J, Frenkel K, Grunberger D, Conney AH. Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells. Carcinogenesis. 17: 761-5. PMID 8625488 DOI: 10.1093/Carcin/17.4.761 |
0.344 |
|
| 1996 |
Suchar LA, Chang RL, Thomas PE, Rosen RT, Lech J, Conney AH. Effects of phenobarbital, dexamethasone, and 3-methylcholanthrene administration on the metabolism of 17 beta-estradiol by liver microsomes from female rats. Endocrinology. 137: 663-76. PMID 8593816 DOI: 10.1210/Endo.137.2.8593816 |
0.406 |
|
| 1995 |
Anfinsen C, Axelrod J, Berg P, Conney A, Horecker B, Kaback R, Kornberg A, Lederberg J, Nirenberg M, Palade G. Wrong move. Nature. 373: 184. PMID 7816120 DOI: 10.1038/373184c0 |
0.638 |
|
| 1995 |
Huang MT, Ma W, Lu YP, Chang RL, Fisher C, Manchand PS, Newmark HL, Conney AH. Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Carcinogenesis. 16: 2493-7. PMID 7586157 DOI: 10.1093/Carcin/16.10.2493 |
0.432 |
|
| 1995 |
D'Armiento J, DiColandrea T, Dalal SS, Okada Y, Huang MT, Conney AH, Chada K. Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis. Molecular and Cellular Biology. 15: 5732-9. PMID 7565725 DOI: 10.1128/Mcb.15.10.5732 |
0.284 |
|
| 1995 |
Wang ZY, Wang LD, Lee MJ, Ho CT, Huang MT, Conney AH, Yang CS. Inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats by green and black tea. Carcinogenesis. 16: 2143-8. PMID 7554067 DOI: 10.1093/Carcin/16.9.2143 |
0.41 |
|
| 1994 |
Conney AH, Chang RL, Jerina DM, Wei SJ. Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite. Drug Metabolism Reviews. 26: 125-63. PMID 8082562 DOI: 10.3109/03602539409029788 |
0.296 |
|
| 1994 |
Wei SJ, Chang RL, Hennig E, Cui XX, Merkler KA, Wong CQ, Yagi H, Jerina DM, Conney AH. Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity. Carcinogenesis. 15: 1729-35. PMID 8055656 DOI: 10.1093/Carcin/15.8.1729 |
0.41 |
|
| 1994 |
Lu YP, Chang RL, Lou YR, Huang MT, Newmark HL, Reuhl KR, Conney AH. Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis. Carcinogenesis. 15: 2363-70. PMID 7955078 DOI: 10.1093/Carcin/15.10.2363 |
0.292 |
|
| 1994 |
Chang RL, Wong CQ, Kline SA, Conney AH, Goldstein BD, Witz G. Mutagenicity of trans,trans-muconaldehyde and its metabolites in V79 cells. Environmental and Molecular Mutagenesis. 24: 112-5. PMID 7925324 DOI: 10.1002/Em.2850240206 |
0.302 |
|
| 1993 |
Lu YP, Chang RL, Huang MT, Conney AH. Inhibitory effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis. Carcinogenesis. 14: 293-7. PMID 8435870 DOI: 10.1093/Carcin/14.2.293 |
0.418 |
|
| 1993 |
Gut I, Conney AH. Trimethylamine N-oxygenation and N-demethylation in rat liver microsomes. Biochemical Pharmacology. 46: 239-44. PMID 8347145 DOI: 10.1016/0006-2952(93)90409-P |
0.385 |
|
| 1993 |
Chang RL, Battista S, Wong CQ, Kumar S, Kole PL, Sikka HC, Balani SK, Jerina DM, Conney AH, Wood AW. Bacterial and mammalian cell mutagenicity of four optically active bay-region 10,11-diol-8,9-epoxides of the nitrogen heterocycle dibenz[a,h]acridine. Carcinogenesis. 14: 2233-7. PMID 8242848 DOI: 10.1093/Carcin/14.11.2233 |
0.306 |
|
| 1992 |
Gut I, Conney AH. The FAD-containing monooxygenase-catalyzed N-oxidation and demethylation of trimethylamine in rat liver microsomes. Drug Metabolism and Drug Interactions. 9: 201-8. PMID 1824076 DOI: 10.1515/DMDI.1991.9.3-4.201 |
0.299 |
|
| 1992 |
Conney AH, Wang ZY, Huang MT, Ho CT, Yang CS. Inhibitory effect of green tea on tumorigenesis by chemicals and ultraviolet light. Preventive Medicine. 21: 361-9. PMID 1614997 DOI: 10.1016/0091-7435(92)90043-H |
0.43 |
|
| 1992 |
Huang MT, Deschner EE, Newmark HL, Wang ZY, Ferraro TA, Conney AH. Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol-induced colonic epithelial cell proliferation and focal areas of dysplasia. Cancer Letters. 64: 117-21. PMID 1611594 DOI: 10.1016/0304-3835(92)90071-3 |
0.453 |
|
| 1992 |
Huang MT, Wang ZY, Georgiadis CA, Laskin JD, Conney AH. Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene Carcinogenesis. 13: 2183-2186. PMID 1423891 DOI: 10.1093/Carcin/13.11.2183 |
0.437 |
|
| 1991 |
Pantuck EJ, Pantuck CB, Kappas A, Conney AH, Anderson KE. Effects of protein and carbohydrate content of diet on drug conjugation. Clinical Pharmacology and Therapeutics. 50: 254-8. PMID 1914359 DOI: 10.1038/Clpt.1991.134 |
0.381 |
|
| 1991 |
Conney AH, Lysz T, Ferraro T, Abidi TF, Manchand PS, Laskin JD, Huang MT. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Advances in Enzyme Regulation. 31: 385-96. PMID 1908616 DOI: 10.1016/0065-2571(91)90025-H |
0.41 |
|
| 1990 |
Robertson FM, Gilmour SK, Beavis AJ, O'Connell SM, Conney AH, Huang MT, Laskin JD, Hietala OA, O'Brien TG. Flow cytometric detection of ornithine decarboxylase activity in epidermal cell subpopulations. Cytometry. 11: 832-6. PMID 2272247 DOI: 10.1002/Cyto.990110709 |
0.265 |
|
| 1988 |
Smart RC, Huang MT, Monteiro-riviere NA, Wong CQ, Mills KJ, Conney AH. Comparison of the effect of sn-1,2-didecanoylglycerol and 12-O-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD-1 mice Carcinogenesis. 9: 2221-2226. PMID 3191568 DOI: 10.1093/Carcin/9.12.2221 |
0.445 |
|
| 1987 |
Loche S, Rifkind AB, Stoner E, Conney AH, New MI. Antipyrine clearance in congenital adrenal hyperplasia. Clinical Endocrinology. 25: 233-9. PMID 3791665 DOI: 10.1111/j.1365-2265.1986.tb01687.x |
0.298 |
|
| 1987 |
Pantuck EJ, Pantuck CB, Conney AH. Effect of streptozotocin-induced diabetes in the rat on the metabolism of fluorinated volatile anesthetics. Anesthesiology. 66: 24-8. PMID 3541691 DOI: 10.1097/00000542-198701000-00005 |
0.297 |
|
| 1987 |
Conney AH. Induction of microsomal cytochrome P-450 enzymes: the first Bernard B. Brodie lecture at Pennsylvania State University. Life Sciences. 39: 2493-518. PMID 3540505 DOI: 10.1016/0024-3205(86)90103-7 |
0.237 |
|
| 1987 |
Chang RL, Wood AW, Conney AH, Yagi H, Sayer JM, Thakker DR, Jerina DM, Levin W. Role of diaxial versus diequatorial hydroxyl groups in the tumorigenic activity of a benzo[a]pyrene bay-region diol epoxide. Proceedings of the National Academy of Sciences of the United States of America. 84: 8633-6. PMID 3479808 DOI: 10.1073/Pnas.84.23.8633 |
0.353 |
|
| 1986 |
Norkus EP, Kuenzig WA, Chau J, Mergens WJ, Conney AH. Inhibitory effect of alpha-tocopherol on the formation of nitrosomorpholine in mice treated with morpholine and exposed to nitrogen dioxide. Carcinogenesis. 7: 357-60. PMID 3948320 DOI: 10.1093/CARCIN/7.3.357 |
0.301 |
|
| 1986 |
Smart RC, Huang MT, Conney AH. sn-1,2-Diacylglycerols mimic the effects of 12-O-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis. Carcinogenesis. 7: 1865-70. PMID 3769135 DOI: 10.1093/carcin/7.11.1865 |
0.355 |
|
| 1986 |
Smart RC, Huang MT, Chang RL, Sayer JM, Jerina DM, Wood AW, Conney AH. Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice. Carcinogenesis. 7: 1669-75. PMID 3757169 DOI: 10.1093/Carcin/7.10.1669 |
0.328 |
|
| 1986 |
Jerina DM, Sayer JM, Agarwal SK, Yagi H, Levin W, Wood AW, Conney AH, Pruess-Schwartz D, Baird WM, Pigott MA. Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons. Advances in Experimental Medicine and Biology. 197: 11-30. PMID 3490131 DOI: 10.1007/978-1-4684-5134-4_2 |
0.308 |
|
| 1986 |
Smart RC, Huang MT, Chang RL, Sayer JM, Jerina DM, Conney AH. Disposition of the naturally occurring antimutagenic plant phenol, ellagic acid, and its synthetic derivatives, 3-O-decylellagic acid and 3,3'-di-O-methylellagic acid in mice. Carcinogenesis. 7: 1663-7. PMID 3093111 DOI: 10.1093/Carcin/7.10.1663 |
0.274 |
|
| 1985 |
Pantuck EJ, Pantuck CB, Ryan DE, Conney AH. Inhibition and stimulation of enflurane metabolism in the rat following a single dose or chronic administration of ethanol. Anesthesiology. 62: 255-62. PMID 4038859 DOI: 10.1097/00000542-198503000-00008 |
0.269 |
|
| 1985 |
Wood AW, Chang RL, Huang MT, Baggiolini E, Partridge JJ, Uskokovic M, Conney AH. Stimulatory effect of 1 alpha, 25-dihydroxyvitamin D3 on the formation of skin tumors in mice treated chronically with 7,12-dimethylbenz[a]anthracene. Biochemical and Biophysical Research Communications. 130: 924-31. PMID 3927913 DOI: 10.1016/0006-291X(85)90505-4 |
0.288 |
|
| 1985 |
Chang RL, Huang MT, Wood AW, Wong CQ, Newmark HL, Yagi H, Sayer JM, Jerina DM, Conney AH. Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse. Carcinogenesis. 6: 1127-33. PMID 3926336 DOI: 10.1093/Carcin/6.8.1127 |
0.351 |
|
| 1985 |
Huang MT, Chang RL, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives. Carcinogenesis. 6: 237-42. PMID 3918802 DOI: 10.1093/Carcin/6.2.237 |
0.291 |
|
| 1985 |
PANTUCK EJ, PANTUCK CB, WEISSMAN C, ASKANAZI J, CONNEY AH, Brown BR. Effects of Parenteral Nutritional Regimens on Oxidative Drug Metabolism Survey of Anesthesiology. 29: 124. DOI: 10.1097/00132586-198504000-00035 |
0.265 |
|
| 1984 |
Anderson KE, Kappas A, Conney AH, Bradlow HL, Fishman J. The influence of dietary protein and carbohydrate on the principal oxidative biotransformations of estradiol in normal subjects. The Journal of Clinical Endocrinology and Metabolism. 59: 103-7. PMID 6725517 DOI: 10.1210/Jcem-59-1-103 |
0.413 |
|
| 1984 |
Pantuck EJ, Pantuck CB, Anderson KE, Wattenberg LW, Conney AH, Kappas A. Effect of brussels sprouts and cabbage on drug conjugation. Clinical Pharmacology and Therapeutics. 35: 161-9. PMID 6692645 DOI: 10.1038/Clpt.1984.22 |
0.394 |
|
| 1984 |
Kappas A, Anderson KE, Conney AH, Pantuck EJ, Fishman J, Bradlow HL. Nutrition-endocrine interactions: induction of reciprocal changes in the delta 4-5 alpha-reduction of testosterone and the cytochrome P-450-dependent oxidation of estradiol by dietary macronutrients in man. Proceedings of the National Academy of Sciences of the United States of America. 80: 7646-9. PMID 6584878 DOI: 10.1073/Pnas.80.24.7646 |
0.436 |
|
| 1984 |
Pantuck EJ, Pantuck CB, Weissman C, Askanazi J, Conney AH. Effects of parenteral nutritional regimens on oxidative drug metabolism. Anesthesiology. 60: 534-6. PMID 6428275 DOI: 10.1097/00000542-198406000-00002 |
0.286 |
|
| 1984 |
Kuenzig W, Chau J, Norkus E, Holowaschenko H, Newmark H, Mergens W, Conney AH. Caffeic and ferulic acid as blockers of nitrosamine formation. Carcinogenesis. 5: 309-13. PMID 6368031 DOI: 10.1093/CARCIN/5.3.309 |
0.275 |
|
| 1983 |
Anderson KE, Schneider J, Pantuck EJ, Pantuck CB, Mudge GH, Welch RM, Conney AH, Kappas A. Acetaminophen metabolism in subjects fed charcoal-broiled beef. Clinical Pharmacology and Therapeutics. 34: 369-74. PMID 6883912 DOI: 10.1038/Clpt.1983.181 |
0.405 |
|
| 1983 |
Ittah Y, Thakker DR, Levin W, Croisy-Delcey M, Ryan DE, Thomas PE, Conney AH, Jerina DM. Metabolism of benzo[c]phenanthrene by rat liver microsomes and by a purified monooxygenase system reconstituted with different isozymes of cytochrome P-450. Chemico-Biological Interactions. 45: 15-28. PMID 6872097 DOI: 10.1016/0009-2797(83)90039-X |
0.322 |
|
| 1983 |
Wood AW, Chang RL, Huang MT, Uskokovic M, Conney AH. 1 alpha, 25-Dihydroxyvitamin D3 inhibits phorbol ester-dependent chemical carcinogenesis in mouse skin. Biochemical and Biophysical Research Communications. 116: 605-11. PMID 6689123 DOI: 10.1016/0006-291X(83)90567-3 |
0.31 |
|
| 1983 |
Levin W, Wood AW, Chang RL, Newman MS, Thakker DR, Conney AH, Jerina DM. The effect of steric strain in the bay-region of polycyclic aromatic hydrocarbons: tumorigenicity of alkyl-substituted benz[a]anthracenes. Cancer Letters. 20: 139-46. PMID 6421476 DOI: 10.1016/0304-3835(83)90042-3 |
0.295 |
|
| 1983 |
Norkus EP, Kuenzig W, Conney AH. Studies on the mutagenic activity of ascorbic acid in vitro and in vivo. Mutation Research. 117: 183-91. PMID 6403856 DOI: 10.1016/0165-1218(83)90166-0 |
0.277 |
|
| 1983 |
Huang MT, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids. Carcinogenesis. 4: 1631-7. PMID 6360409 DOI: 10.1093/Carcin/4.12.1631 |
0.336 |
|
| 1983 |
SAYER JM, YAGI H, WOOD AW, CONNEY AH, JERINA DM. ChemInform Abstract: EXTREMELY FACILE REACTION BETWEEN THE ULTIMATE CARCINOGEN BENZO(A)PYRENE-7,8-DIOL 9,10-EPOXIDE AND ELLAGIC ACID Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198301145 |
0.233 |
|
| 1982 |
Lasker JM, Huang M-T, Conney AH. In vivo activation of zoxazolamine metabolism by flavone. Science (New York, N.Y.). 216: 1419-21. PMID 7089530 DOI: 10.1126/SCIENCE.7089530 |
0.33 |
|
| 1982 |
Pantuck EJ, Pantuck CB, Anderson KE, Conney AH, Kappas A. Cigarette smoking and chlorpromazine disposition and actions. Clinical Pharmacology and Therapeutics. 31: 533-8. PMID 7060333 DOI: 10.1038/clpt.1982.72 |
0.225 |
|
| 1982 |
Paigen B, Ward E, Steenland K, Bolanowska W, Gessner T, Chang RL, Wood AW, Conney AH. Absence of seasonal variation in antipyrine metabolism. Clinical Pharmacology and Therapeutics. 31: 144-50. PMID 7056021 DOI: 10.1038/Clpt.1982.23 |
0.277 |
|
| 1982 |
Vyas KP, Thakker DR, Levin W, Yagi H, Conney AH, Jerina DM. Stereoselective metabolism of the optical isomers of trans-1,2-dihydroxy-1,2-dihydrophenanthrene to bay-region diol epoxides by rat liver microsomes. Chemico-Biological Interactions. 38: 203-13. PMID 7055851 DOI: 10.1016/0009-2797(82)90040-0 |
0.328 |
|
| 1982 |
Wood AW, Sayer JM, Newmark HL, Yagi H, Michaud DP, Jerina DM, Conney AH. Mechanism of the inhibition of mutagenicity of a benzo[a]pyrene 7,8-diol 9,10-epoxide by riboflavin 5'-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 79: 5122-6. PMID 6813854 DOI: 10.1073/Pnas.79.17.5122 |
0.402 |
|
| 1982 |
Wood AW, Huang MT, Chang RL, Newmark HL, Lehr RE, Yagi H, Sayer JM, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: exceptional activity of ellagic acid. Proceedings of the National Academy of Sciences of the United States of America. 79: 5513-7. PMID 6752950 DOI: 10.1073/Pnas.79.18.5513 |
0.316 |
|
| 1982 |
Anderson KE, Conney AH, Kappas A. Nutritional influences on chemical biotransformations in humans. Nutrition Reviews. 40: 161-71. PMID 6750455 DOI: 10.1111/J.1753-4887.1982.Tb05298.X |
0.33 |
|
| 1982 |
Levin W, Wood A, Chang R, Ryan D, Thomas P, Yagi H, Thakker D, Vyas K, Boyd C, Chu SY, Conney A, Jerina D. Oxidative metabolism of polycyclic aromatic hydrocarbons to ultimate carcinogens. Drug Metabolism Reviews. 13: 555-80. PMID 6290166 DOI: 10.3109/03602538209011087 |
0.256 |
|
| 1982 |
Pantuck EJ, Pantuck CB, Anderson KE, Conney AH, Kappas A. Cigarette smoking and chlorpromazine disposition and actions Journal of Clinical Psychopharmacology. 2: 362. DOI: 10.1097/00004714-198210000-00019 |
0.189 |
|
| 1982 |
Sayer JM, Yagi H, Wood AW, Conney AH, Jerina DM. Extremely facile reaction between the ultimate carcinogen benzo[a]pyrene-7,8-diol 9,10-epoxide and ellagic acid Journal of the American Chemical Society. 104: 5562-5564. DOI: 10.1021/Ja00384A081 |
0.231 |
|
| 1981 |
Thakker DR, Levin W, Yagi H, Conney AH, Jerina DM. Regio- and stereoselectivity of hepatic cytochrome P-450 toward polycyclic aromatic hydrocarbon substrates. Advances in Experimental Medicine and Biology. 136: 525-39. PMID 7344478 DOI: 10.1007/978-1-4757-0674-1_39 |
0.288 |
|
| 1981 |
Vyas KP, Yagi H, Levin W, Conney AH, Jerina DM. Metabolism of (-)-trans-(3R, 4R)-dihydroxy-3,4-dihydrochrysene to diol epoxides by liver microsomes. Biochemical and Biophysical Research Communications. 98: 961-9. PMID 7225135 DOI: 10.1016/0006-291X(81)91204-3 |
0.326 |
|
| 1981 |
Jerina DM, Sayer JM, Yagi H, Croisy-Delcey M, Ittah Y, Thakker DR, Wood AW, Chang RL, Levin W, Conney AH. Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene. Advances in Experimental Medicine and Biology. 136: 501-23. PMID 7046379 DOI: 10.1007/978-1-4757-0674-1_38 |
0.243 |
|
| 1981 |
Conney AH, Buening MK, Pantuck EJ, Pantuck CB, Fortner JG, Anderson KE, Kappas A. Regulation of human drug metabolism by dietary factors. Ciba Foundation Symposium. 76: 147-67. PMID 6906262 DOI: 10.1002/9780470720592.CH9 |
0.331 |
|
| 1980 |
MacLeod MC, Levin W, Conney AH, Lehr RE, Mansfield BK, Jerina DM, Selkirk JK. Metabolism of benzo(e)pyrene by rat liver microsomal enzymes. Carcinogenesis. 1: 165-73. PMID 22282997 DOI: 10.1093/Carcin/1.2.165 |
0.297 |
|
| 1980 |
Riester EF, Pantuck EJ, Pantuck CB, Passananti GT, Vesell ES, Conney AH. Antipyrine metabolism during the menstrual cycle. Clinical Pharmacology and Therapeutics. 28: 384-91. PMID 7408398 DOI: 10.1038/clpt.1980.177 |
0.264 |
|
| 1980 |
Levin W, Kuntzman R, Conney AH. Stimulatory effect of phenobarbital on the metabolism of the oral contraceptive 17 alpha-ethynylestradiol-3-methyl ether (mestranol) by rat liver microsomes. Pharmacology. 19: 249-55. PMID 538079 DOI: 10.1159/000137319 |
0.326 |
|
| 1979 |
Pantuck EJ, Pantuck CB, Garland WA, Min BH, Wattenberg LW, Anderson KE, Kappas A, Conney AH. Stimulatory effect of brussels sprouts and cabbage on human drug metabolism. Clinical Pharmacology and Therapeutics. 25: 88-95. PMID 758247 DOI: 10.1002/Cpt197925188 |
0.398 |
|
| 1979 |
Thakker DR, Levin W, Yagi H, Turujman S, Kapadia D, Conney AH, Jerina DM. Absolute stereochemistry of the trans-dihydrodiols formed from benzo[a]anthracene by liver microsomes. Chemico-Biological Interactions. 27: 145-61. PMID 498352 DOI: 10.1016/0009-2797(79)90122-4 |
0.327 |
|
| 1979 |
Anderson KE, Conney AH, Kappas A. Nutrition and oxidative drug metabolism in man: relative influence of dietary lipids, carbohydrate, and protein. Clinical Pharmacology and Therapeutics. 26: 493-501. PMID 487697 DOI: 10.1002/Cpt1979264493 |
0.394 |
|
| 1979 |
Chang RL, Wood AW, Levin W, Mah HD, Thakker DR, Jerina DM, Conney AH. Differences in mutagenicity and cytotoxicity of (+)- and (-)-benzo[a]pyrene 4,5-oxide: a synergistic interaction of enantiomers. Proceedings of the National Academy of Sciences of the United States of America. 76: 4280-4. PMID 388437 DOI: 10.1073/Pnas.76.9.4280 |
0.377 |
|
| 1979 |
Alvares AP, Pantuck EJ, Anderson KE, Kappas A, Conney AH. Regulation of drug metabolism in man by environmental factors. Drug Metabolism Reviews. 9: 185-205. PMID 385270 DOI: 10.3109/03602537908993890 |
0.246 |
|
| 1979 |
Alvares AP, Kappas A, Eiseman JL, Anderson KE, Pantuck CB, Pantuck EJ, Hsiao KC, Garland WA, Conney AH. Intraindividual variation in drug disposition. Clinical Pharmacology and Therapeutics. 26: 407-19. PMID 314881 DOI: 10.1002/cpt1979264407 |
0.277 |
|
| 1979 |
Wislocki PG, Buening MK, Levin W, Lehr RE, Thakker DR, Jerina DM, Conney AH. Tumorigenicity of the diastereomeric benz[a]anthracene 3,4-diol-1,2-epoxides and the (+)- and (-)-enantiomers of benz[a]anthracene 3,4-dihydrodiol in newborn mice. Journal of the National Cancer Institute. 63: 201-4. PMID 286829 DOI: 10.1093/Jnci/63.1.201 |
0.331 |
|
| 1979 |
JERINA DM, THAKKER DR, YAGI DR, LEVIN W, WOOD AW, CONNEY AH. ChemInform Abstract: CARCINOGENICITY OF BENZO(A)PYRENE DERIVATIVES: THE BAY REGION THEORY Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197914385 |
0.269 |
|
| 1978 |
Klutch A, Levin W, Chang RL, Vane F, Conney AH. Formation of a thiomethyl metabolite of phenacetin and acetaminophen in dogs and man. Clinical Pharmacology and Therapeutics. 24: 287-93. PMID 688722 DOI: 10.1002/cpt1978243287 |
0.247 |
|
| 1978 |
Wislocki PG, Kapitulnik J, Levin W, Conney AH. Tumorigenicity of benzo[alpha]pyrene 4,5-,7,8-,9,10- and 11,12-oxides in newborn mice. Cancer Letters. 5: 191-7. PMID 688201 DOI: 10.1016/S0304-3835(78)80038-X |
0.284 |
|
| 1978 |
Kappas A, Alvares AP, Anderson KE, Pantuck EJ, Pantuck CB, Chang R, Conney AH. Effect of charcoal-broiled beef on antipyrine and theophylline metabolism. Clinical Pharmacology and Therapeutics. 23: 445-50. PMID 630792 DOI: 10.1002/cpt1978234445 |
0.257 |
|
| 1978 |
Thakker DR, Levin W, Wood AW, Conney AH, Stoming TA, Jerina DM. Metabolic formation of 1,9,10-trihydroxy-9,10-dihydro-3-methylcholanthrene: a potential proximate carcinogen from 3-methylcholanthrene. Journal of the American Chemical Society. 100: 645-7. PMID 624805 DOI: 10.1002/Chin.197819132 |
0.268 |
|
| 1978 |
Buening MK, Wislocki PG, Levin W, Yagi H, Thakker DR, Akagi H, Koreeda M, Jerina DM, Conney AH. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Proceedings of the National Academy of Sciences of the United States of America. 75: 5358-61. PMID 281685 DOI: 10.1073/Pnas.75.11.5358 |
0.359 |
|
| 1978 |
Jerina DM, Levin W, Thakker DR, Wood AW, Yagi H, Conney AH. Carcinogenicity of benzo[a]pyrene derivatives: The bay region theory Pure and Applied Chemistry. 50: 1033-1044. DOI: 10.1351/Pac197850091033 |
0.269 |
|
| 1978 |
THAKKER DR, LEVIN W, WOOD AW, CONNEY AH, STOMING TA, JERINA DM. ChemInform Abstract: METABOLIC FORMATION OF 1,9,10-TRIHYDROXY-9,10-DIHYDRO-3-METHYLCHOLANTHRENE- A POTENTIAL PROXIMATE CARCINOGEN FROM 3-METHYLCHOLANTHRENE Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197819132 |
0.269 |
|
| 1977 |
Kappas A, Anderson KE, Conney AH, Alvares AP. Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man. Clinical Pharmacology and Therapeutics. 20: 643-53. PMID 991535 DOI: 10.1002/Cpt1976206643 |
0.379 |
|
| 1977 |
Kapitulnik J, Levin W, Poppers PJ, Tomaszewski JE, Jerina DM, Conney AH. Comparison of the hydroxylation of zoxazolamine and benzo[a]pyrene in human placenta: effect of cigarette smoking. Clinical Pharmacology and Therapeutics. 20: 557-64. PMID 975727 DOI: 10.1002/cpt1976205557 |
0.271 |
|
| 1977 |
Kuntzman R, Pantuck EJ, Kaplan SA, Conney AH. Phenacetin metabolism: effect of hydrocarbons and cigarette smoking. Clinical Pharmacology and Therapeutics. 22: 757-64. PMID 913035 DOI: 10.1002/cpt1977225part2757 |
0.263 |
|
| 1977 |
Kapitulnik J, Poppers PJ, Buening MK, Fortner JG, Conney AH. Activation of monooxygenases in human liver by 7,8-benzoflavone. Clinical Pharmacology and Therapeutics. 22: 475-84. PMID 902460 DOI: 10.1002/cpt1977224475 |
0.301 |
|
| 1977 |
Thakker DR, Yagi H, Akagi H, Koreeda M, Lu AH, Levin W, Wood AW, Conney AH, Jerina DM. Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides. Chemico-Biological Interactions. 16: 281-300. PMID 862130 DOI: 10.1016/0009-2797(77)90108-9 |
0.299 |
|
| 1977 |
Garland WA, Hsiao KC, Pantuck EJ, Conney AH. Quantitative determination of phenacetin and its metabolite acetaminophen by GLC-chemical ionization mass spectrometry. Journal of Pharmaceutical Sciences. 66: 340-4. PMID 845798 DOI: 10.1002/JPS.2600660309 |
0.233 |
|
| 1977 |
Seifried HE, Birkett DJ, Levin W, Lu AY, Conney AH, Jerina DM. Metabolism of benzo[a]pyrene. Effect of 3-methylcholanthrene pretreatment on metabolism by microsomes from lungs of genetically "responsive" and "nonresponsive" mice. Archives of Biochemistry and Biophysics. 178: 256-63. PMID 836034 DOI: 10.1016/0003-9861(77)90190-4 |
0.316 |
|
| 1977 |
Conney AH, Pantuck EJ, Kuntzman R, Kappas A, Anderson KE, Alvares AP. Nutrition and chemical biotransformations in man. Clinical Pharmacology and Therapeutics. 22: 707-20. PMID 334440 DOI: 10.1002/Cpt1977225Part2707 |
0.317 |
|
| 1977 |
Wood AW, Levin W, Ryan D, Thomas PE, Yagi H, Mah HD, Thakker DR, Jerina DM, Conney AH. High mutageniticity of metabolically activated chrysene 1,2 dihydrodiol: evidence for bay region activation of chrysene. Biochemical and Biophysical Research Communications. 78: 847-54. PMID 334179 DOI: 10.1016/0006-291X(77)90500-9 |
0.301 |
|
| 1977 |
Wood AW, Chang RL, Levin W, Yagi H, Thakker DR, Jerina DM, Conney AH. Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides. Biochemical and Biophysical Research Communications. 77: 1389-96. PMID 332178 DOI: 10.1016/S0006-291X(77)80133-2 |
0.197 |
|
| 1977 |
Wood AW, Chang RL, Levin W, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Mutagenicity and cytotoxicity of benz[a]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides Proceedings of the National Academy of Sciences of the United States of America. 74: 2746-2750. PMID 331315 DOI: 10.1073/Pnas.74.7.2746 |
0.273 |
|
| 1977 |
Wood AW, Levin W, Chang RL, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol. Proceedings of the National Academy of Sciences of the United States of America. 74: 3176-9. PMID 269381 DOI: 10.1073/Pnas.74.8.3176 |
0.333 |
|
| 1977 |
Tomaszewski JE, Jerina DM, Levin W, Conney AH. A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system. Archives of Biochemistry and Biophysics. 176: 788-98. PMID 10855 DOI: 10.1016/0003-9861(76)90223-X |
0.339 |
|
| 1977 |
COOPER DY, SCHLEYER H, ROSENTHAL O, LEVIN W, LU AYH, KUNTZMAN R, CONNEY AH. Inhibition by CO of Hepatic Benzo[a]pyrene Hydroxylation and Its Reversal by Monochromatic Light European Journal of Biochemistry. 74: 69-75. DOI: 10.1111/J.1432-1033.1977.TB11367.X |
0.245 |
|
| 1977 |
KAPITULNIK J, LEVIN W, CONNEY AH, YAGI H, JERINA DM. ChemInform Abstract: BENZO(A)PYRENE 7,8-DIHYDRODIOL IS MORE CARCINOGENIC THAN BENZO(A)PYRENE IN NEWBORN MICE Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/Chin.197730359 |
0.28 |
|
| 1976 |
Holder GM, Yagi H, Jerina DM, Levin W, Lu AY, Conney AH. Metabolism of benzo[a]pyrene. Effect of substrate concentration and 3-methylcholanthrene pretreatment on hepatic metabolism by microsomes from rats and mice. Archives of Biochemistry and Biophysics. 170: 557-66. PMID 1190779 DOI: 10.1016/0003-9861(75)90151-4 |
0.359 |
|
| 1976 |
Thakker DR, Yagi H, Lu AY, Levin W, Conney AH. Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides. Proceedings of the National Academy of Sciences of the United States of America. 73: 3381-5. PMID 1068451 DOI: 10.1073/Pnas.73.10.3381 |
0.289 |
|
| 1976 |
Alvares AP, Anderson KE, Conney AH, Kappas A. Interactions between nutritional factors and drug biotransformations in man. Proceedings of the National Academy of Sciences of the United States of America. 73: 2501-4. PMID 1065903 DOI: 10.1073/Pnas.73.7.2501 |
0.366 |
|
| 1976 |
Levin W, Wood AW, Yagi H, Dansette PM, Jerina DM, Conney AH. Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin. Proceedings of the National Academy of Sciences of the United States of America. 73: 243-7. PMID 1061121 DOI: 10.1073/Pnas.73.1.243 |
0.364 |
|
| 1976 |
Kamm JJ, Dashman T, Conney AH, Burns JJ. Effect of ascorbic acid on amine-nitrite toxicity. Annals of the New York Academy of Sciences. 258: 169-74. PMID 1060400 DOI: 10.1111/j.1749-6632.1975.tb29276.x |
0.248 |
|
| 1976 |
Pantuck EJ, Hsiao KC, Conney AH, Garland WA, Kappas A, Anderson KE, Alvares AP. Effect of charcoal-broiled beef on phenacetin metabolism in man. Science (New York, N.Y.). 194: 1055-7. PMID 982059 DOI: 10.1126/SCIENCE.982059 |
0.3 |
|
| 1976 |
Chang RL, Wood AW, Dixon WR, Conney AH, Anderson KE, Eiseman J, Alvares AP. Antipyrine: radioimmunoassay in plasma and saliva following administration of a high dose and a low dose. Clinical Pharmacology and Therapeutics. 20: 219-26. PMID 947654 DOI: 10.1002/Cpt1976202219 |
0.367 |
|
| 1976 |
Wood AW, Levin W, Lu AYH, Ryan D, West SB, Lehr RE, Schaefer-Ridder M, Jerina DM, Conney AH. Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: Evidence for bay region activation of carcinogenic polycyclic hydrocarbons Biochemical and Biophysical Research Communications. 72: 680-686. PMID 791280 DOI: 10.1016/S0006-291X(76)80093-9 |
0.304 |
|
| 1976 |
Wislocki PG, Wood AW, Chang RL, Levin W, Yagi H, Hernandez O, Jerina DM, Conney AH. High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene. Biochemical and Biophysical Research Communications. 68: 1006-12. PMID 769789 DOI: 10.1016/0006-291X(76)91246-8 |
0.357 |
|
| 1975 |
Jacobson M, Levin W, Poppers PJ, Wood AW, Conney AH. Comparison of the O-dealkylation of 7-ethoxycoumarin and the hydroxylation of benzo(a)pyrene in human placenta. Effect of cigarette smoking. Clinical Pharmacology and Therapeutics. 16: 701-10. PMID 4417865 DOI: 10.1002/cpt1974164701 |
0.217 |
|
| 1975 |
Lu AY, Levin W, West S, Jacobson M, Ryan D, Kuntzman R, Conney AH. The role of cytochrome P-450 and P-448 in drug and steroid hydroxylations. Annals of the New York Academy of Sciences. 212: 156-74. PMID 4155922 DOI: 10.1111/J.1749-6632.1973.Tb47594.X |
0.24 |
|
| 1975 |
Jacobson MM, Levin W, Conney AH. Studies on bilirubin and steroid glucuronidation by rat liver microsomes Biochemical Pharmacology. 24: 655-662. PMID 1125067 DOI: 10.1016/0006-2952(75)90240-3 |
0.341 |
|
| 1975 |
Wood AW, Goode RL, Chang RL, Levin W, Conney AH, Yagi H, Dansette PM, Jerina DM. Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols. Proceedings of the National Academy of Sciences of the United States of America. 72: 3176-80. PMID 1103140 DOI: 10.1073/Pnas.72.8.3176 |
0.352 |
|
| 1975 |
Levin W, Lu AY, Ryan D, West S, Kuntzman R, Conney AH. Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes Advances in Experimental Medicine and Biology. 58: 1-24. PMID 808108 DOI: 10.1007/978-1-4615-9026-2_1 |
0.3 |
|
| 1975 |
Lu AY, Levin W, West SB, Vore M, Ryan D, Kuntzman R, Conney AH. Role of cytochrome b5 in NADPH-and NADH-dependent hydroxylation by the reconstituted cytochrome P-450- or P-448-containing system Advances in Experimental Medicine and Biology. 58: 447-466. PMID 239545 DOI: 10.1007/978-1-4615-9026-2_31 |
0.233 |
|
| 1974 |
Pantuck EJ, Hsiao KC, Maggio A, Nakamura K, Kuntzman R, Conney AH. Effect of cigarette smoking on phenacetin metabolism. Clinical Pharmacology and Therapeutics. 15: 9-17. PMID 4808745 DOI: 10.1002/cpt19741519 |
0.224 |
|
| 1974 |
Nakamura K, Kuntzman R, Maggio A, Conney AH. Decrease in morphine's analgesic action and increase in its cataleptic action by 6-hydroxydopamine injected bilaterally into caudate and putamen areas; partial restoration by L-DOPA plus decarboxylase inhibition. Neuropharmacology. 12: 1153-60. PMID 4798737 DOI: 10.1016/0028-3908(73)90072-5 |
0.248 |
|
| 1974 |
Holder G, Yagi H, Dansette P, Jerina DM, Levin W, Lu AY, Conney AH. Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography Proceedings of the National Academy of Sciences of the United States of America. 71: 4356-4360. PMID 4530987 DOI: 10.1073/Pnas.71.11.4356 |
0.407 |
|
| 1974 |
Dansette PM, Yagi H, Jerina DM, Daly JW, Levin W, Lu AY, Kuntzman R, Conney AH. Assay and partial purification of epoxide hydrase from rat liver microsomes. Archives of Biochemistry and Biophysics. 164: 511-7. PMID 4460878 DOI: 10.1016/0003-9861(74)90061-7 |
0.292 |
|
| 1974 |
Wood AW, Conney AH. Genetic variation in coumarin hydroxylase activity in the mouse (Mus musculus) Science. 185: 612-614. PMID 4366489 DOI: 10.1126/science.185.4151.612 |
0.278 |
|
| 1974 |
Conney AH, Coutinho C, Koechlin B, Swarm R, Cheripko JA, Impellizzeri C, Baruth H. From animals to man: metabolic considerations. Clinical Pharmacology and Therapeutics. 16: 176-82. PMID 4210525 DOI: 10.1002/cpt1974161part2176 |
0.256 |
|
| 1973 |
Conney AH, Burns JJ. Metabolic interactions among environmental chemicals and drugs. Science (New York, N.Y.). 178: 576-86. PMID 5086390 DOI: 10.1126/science.178.4061.576 |
0.286 |
|
| 1973 |
Conney AH. Editorial: Carcinogen metabolism and human cancer. The New England Journal of Medicine. 289: 971-3. PMID 4743623 DOI: 10.1056/NEJM197311012891810 |
0.262 |
|
| 1973 |
Nakamura K, Kuntzman R, Maggio AC, Augulis V, Conney AH. Infuluence of 6-hydroxydopamine on the effect of morphine on the tail-flick latency. Psychopharmacologia. 31: 177-89. PMID 4722208 DOI: 10.1007/BF00419817 |
0.199 |
|
| 1973 |
Conney AH, Levin W, Jacobson M, Kuntzman R. Effects of drugs and environmental chemicals on steroid metabolism. Clinical Pharmacology and Therapeutics. 14: 727-41. PMID 4719977 DOI: 10.1002/cpt1973144part2727 |
0.266 |
|
| 1973 |
Levin W, Lu AY, Ryan D, West S, Kuntzman R, Conney AH. Partial purification and properties of cytochromes P-450 and P-448 from rat liver microsomes. Archives of Biochemistry and Biophysics. 153: 543-53. PMID 4662099 DOI: 10.1016/0003-9861(72)90373-6 |
0.292 |
|
| 1973 |
Oesch F, Jerina DM, Daly JW, Lu AY, Kuntzman R, Conney AH. A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions. Archives of Biochemistry and Biophysics. 153: 62-7. PMID 4650623 DOI: 10.1016/0003-9861(72)90420-1 |
0.273 |
|
| 1973 |
Kamm JJ, Dashman T, Conney AH, Burns JJ. Protective effect of ascorbic acid on hepatotoxicity caused by sodium nitrite plus aminopyrine. Proceedings of the National Academy of Sciences of the United States of America. 70: 747-9. PMID 4514987 DOI: 10.1073/PNAS.70.3.747 |
0.284 |
|
| 1973 |
Alvares AP, Kappas A, Levin W, Conney AH. Inducibility of benzo( )pyrene hydroxylase in human skin by polycylic hydrocarbons. Clinical Pharmacology and Therapeutics. 14: 30-40. PMID 4405105 DOI: 10.1002/cpt197314130 |
0.255 |
|
| 1973 |
Lu AY, Somogyi A, West S, Kuntzman R, Conney AH. Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes. Archives of Biochemistry and Biophysics. 152: 457-62. PMID 4344124 DOI: 10.1016/0003-9861(72)90239-1 |
0.34 |
|
| 1973 |
Nakamura K, Kuntzman R, Maggio A, Conney AH. Restoration of morphine analgesia in morphine-tolerant rats after the intraventricular administration of 6-hydroxydopamine. The Journal of Pharmacy and Pharmacology. 25: 584-7. PMID 4147063 DOI: 10.1111/j.2042-7158.1973.tb09166.x |
0.219 |
|
| 1972 |
Kuntzman R, Lu AY, West S, Jacobson M, Conney AH. The importance of cytochrome P-450 and P-448 in determining the specificity of the reconstituted liver microsomal hydroxylation system. Chemico-Biological Interactions. 3: 287-8. PMID 5133004 DOI: 10.1016/0009-2797(71)90063-9 |
0.268 |
|
| 1972 |
Pantuck EJ, Kuntzman R, Conney AH. Decreased concentration of phenacetin in plasma of cigarette smokers. Science (New York, N.Y.). 175: 1248-50. PMID 5061244 DOI: 10.1126/science.175.4027.1248 |
0.246 |
|
| 1972 |
Conney AH, Chang R, Levin WM, Garbut A, Munro-Faure AD, Peck AW, Bye A. Effects of piperonyl butoxide on drug metabolism in rodents and man. Archives of Environmental Health. 24: 97-106. PMID 5007655 DOI: 10.1080/00039896.1972.10666058 |
0.268 |
|
| 1972 |
Somogyi A, Conney AH, Kuntzman R, Solymoss B. Protection against dimethylnitrosamine toxicity by pregnenolone-16 -carbonitrile. Nature: New Biology. 237: 61-3. PMID 4503752 DOI: 10.1038/NEWBIO237061A0 |
0.23 |
|
| 1972 |
Nakamura K, Kuntzman R, Maggio A, Conney AH. Effect of 6-hydroxydopamine on catecholamine concentrations and behaviour in the morphine-tolerant rat. The Journal of Pharmacy and Pharmacology. 24: 484-7. PMID 4403831 DOI: 10.1111/j.2042-7158.1972.tb09037.x |
0.249 |
|
| 1972 |
Levin W, Conney AH, Alvares AP, Merkatz I, Kappas A. Induction of benzo( )pyrene hydroxylase in human skin. Science (New York, N.Y.). 176: 419-20. PMID 4402068 DOI: 10.1126/science.176.4033.419 |
0.295 |
|
| 1972 |
Somogyi A, Kovacs K, Solymoss B, Kuntzman R, Conney AH. Suppression of 7,12-dimethylbenz( )anthracene-produced adrenal necrosis by steroids capable of inducing aryl hydrocarbon hydroxylase. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 10: 1261-71. PMID 4111407 DOI: 10.1016/0024-3205(71)90233-5 |
0.293 |
|
| 1971 |
Kuntzman R, Levin W, Jacobson M, Conney AH. Studies on microsomal hydroxylation and the demonstration of a new carbon monoxide binding pigment in liver microsomes. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 7: 215-24. PMID 5760143 DOI: 10.1016/0024-3205(68)90309-3 |
0.351 |
|
| 1971 |
Welch RM, Loh A, Conney AH. Cigarette smoke: Stimulatory effect on metabolism of 3,4-benzpyrene by enzymes in rat lung Life Sciences. 10: 215-221. PMID 5581603 DOI: 10.1016/0024-3205(71)90250-5 |
0.25 |
|
| 1971 |
Lu AY, Kuntzman R, West S, Conney AH. Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. I. Determination of substrate specificity by the cytochrome P-450 and P-448 fractions. Biochemical and Biophysical Research Communications. 42: 1200-6. PMID 5550806 DOI: 10.1016/0006-291X(71)90033-7 |
0.31 |
|
| 1971 |
Schlede E, Conney AH. Induction of benzol(alpha)pyrene hydroxylase activity in rat skin. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 9: 1295-303. PMID 5487667 DOI: 10.1016/0024-3205(70)90129-3 |
0.268 |
|
| 1971 |
Conney AH, Welch R, Kuntzman R, Chang R, Jacobson M, Munro-Faure AD, Peck AW, Bye A, Poland A, Poppers PJ, Finster M, Wolff JA. Effects of environmental chemicals on the metabolism of drugs, carcinogens, and normal body constituents in man. Annals of the New York Academy of Sciences. 179: 155-72. PMID 4108036 DOI: 10.1111/j.1749-6632.1971.tb46897.x |
0.276 |
|
| 1971 |
Welch RM, Levin W, Kuntzman R, Jacobson M, Conney AH. Effect of halogenated hydrocarbon insecticides on the metabolism and uterotropic action of estrogens in rats and mice. Toxicology and Applied Pharmacology. 19: 234-46. PMID 4105824 DOI: 10.1016/0041-008X(71)90109-8 |
0.323 |
|
| 1970 |
Kuntzman R, Tsai I, Chang R, Conney AH. Disposition of bretylium in man and rat A sensitive chemical method for its estimation in plasma and urine Clinical Pharmacology &Amp; Therapeutics. 11: 829-837. PMID 5481571 DOI: 10.1002/cpt1970116829 |
0.277 |
|
| 1970 |
Poland A, Smith D, Kuntzman R, Jacobson M, Conney AH. Effect of intensive occupational exposure to DDT on phenylbutazone and cortisol metabolism in human subjects. Clinical Pharmacology and Therapeutics. 11: 724-32. PMID 5455634 DOI: 10.1002/cpt1970115724 |
0.244 |
|
| 1970 |
Salvador RA, Atkins C, Haber S, Kozma C, Conney AH. Effect of phenobarbital and chlorcyclizine on the development of atheromatosis in the cholesterol-fed rabbit. Biochemical Pharmacology. 19: 1975-81. PMID 4398025 DOI: 10.1016/0006-2952(70)90293-5 |
0.241 |
|
| 1970 |
Salvador RA, Atkins C, Haber S, Conney AH. Changes in the serum concentration of cholesterol, triglycerides and phospholipids in the mouse and rat after administration of either chlorcyclizine or phenobarbital. Biochemical Pharmacology. 19: 1463-9. PMID 4398011 DOI: 10.1016/0006-2952(70)90062-6 |
0.27 |
|
| 1969 |
Levin W, Welch RM, Conney AH. Inhibitory effect of phenobarbital or chlordane pretreatment on the androgen-induced increase in seminal vesicle weight in the rat Steroids. 13: 155-161. PMID 5773886 DOI: 10.1016/0039-128X(69)90003-8 |
0.415 |
|
| 1969 |
Welch RM, Levin W, Conney AH. Estrogenic action of DDT and its analogs Toxicology and Applied Pharmacology. 14: 358-367. PMID 5772860 DOI: 10.1016/0041-008X(69)90117-3 |
0.402 |
|
| 1969 |
Conney AH. Drug metabolism and therapeutics. The New England Journal of Medicine. 280: 653-60. PMID 4974536 DOI: 10.1056/NEJM196903202801210 |
0.252 |
|
| 1969 |
Welch RM, Harrison YE, Gommi BW, Poppers PJ, Finster M, Conney AH. Stimulatory effect of cigarette smoking on the hydroxylation of 3,4-benzpyrene and the N-demethylation of 3-methyl-4-monomethylaminoazobenzene by enzymes in human placenta. Clinical Pharmacology and Therapeutics. 10: 100-9. PMID 4387671 DOI: 10.1002/cpt1969101100 |
0.221 |
|
| 1969 |
Welch RM, Harrison YE, Conney AH, Burns JJ. An experimental model in dogs for studying interactions of drugs with bishydroxycoumarin Clinical Pharmacology and Therapeutics. 10: 817-825. PMID 4186901 DOI: 10.1002/Cpt1969106817 |
0.381 |
|
| 1969 |
MAUSER HM, WOLFF JA, FINSTER M, POPPERS PJ, PANTUCK E, KUNTZMAN R, CONNEY AH. The Newborn Obstetrical & Gynecological Survey. 24: 57. DOI: 10.1097/00006254-196901000-00006 |
0.183 |
|
| 1968 |
Prescott LF, Sansur M, Levin W, Conney AH. The comparative metabolism of phenacetin and N-acetyl-p-aminophenol in man, with particular reference to effects on the kidney. Clinical Pharmacology and Therapeutics. 9: 605-14. PMID 5676801 DOI: 10.1002/cpt196895605 |
0.266 |
|
| 1968 |
Pantuck E, Conney AH, Kuntzman R. Effect of phenobarbital on the metabolism of pentobarbital and meperidine in fetal rabbits and rats. Biochemical Pharmacology. 17: 1441-7. PMID 5659787 DOI: 10.1016/0006-2952(68)90080-4 |
0.287 |
|
| 1968 |
Levin W, Welch RM, Conney AH. Decreased uterotropic potency of oral contraceptives in rats pretreated with phenobarbital Endocrinology. 83: 149-156. PMID 5659427 DOI: 10.1210/Endo-83-1-149 |
0.436 |
|
| 1968 |
Kuntzman R, Jacobson M, Levin W, Conney AH. Stimulatory effect of N-phenylbarbital (phetharbital) on cortisol hydroxylation in man. Biochemical Pharmacology. 17: 565-71. PMID 5649552 DOI: 10.1016/0006-2952(68)90272-4 |
0.368 |
|
| 1968 |
Welch RM, Harrison YE, Conney AH, Poppers PJ, Finster M. Cigarette smoking: stimulatory effect on metabolism of 3,4-benzpyrene by enzymes in human placenta. Science (New York, N.Y.). 160: 541-2. PMID 5644060 DOI: 10.1126/science.160.3827.541 |
0.248 |
|
| 1968 |
Kuntzman R, Welch R, Conney AH. Factors influencing steroid hydroxylases in liver microsomes. Advances in Enzyme Regulation. 4: 149-60. PMID 4169942 DOI: 10.1016/0065-2571(66)90012-4 |
0.262 |
|
| 1968 |
Conney AH, Taylor WI, Hager GP. Research Achievement Awards Journal of the American Pharmaceutical Association (1961). 8: 336. DOI: 10.1016/S0003-0465(16)30663-2 |
0.173 |
|
| 1967 |
Levin W, Welch RM, Conney AH. Effect of chronic phenobarbital treatment on the liver microsomal metabolism and uterotropic action of 17-beta-estradiol Endocrinology. 80: 135-140. PMID 6067588 DOI: 10.1210/Endo-80-1-135 |
0.438 |
|
| 1967 |
Conney AH, Welch RM, Kuntzman R, Burns JJ. Effects of pesticides on drug and steroid metabolism Clinical Pharmacology and Therapeutics. 8: 2-10. PMID 6016284 DOI: 10.1002/Cpt196781Part12 |
0.426 |
|
| 1967 |
Klutch A, Harfenist M, Conney AH. 2-Hydroxyacetophenetidine, a new metabolite of acetophenetidine. Journal of Medicinal Chemistry. 9: 63-6. PMID 5959744 DOI: 10.1021/JM00319A017 |
0.219 |
|
| 1967 |
Conney AH, Levin W. Induction of hepatic 7,12-dimethylbenz(alpha)anthracene metabolism by polycyclic aromatic hydrocarbons and aromatic azo derivatives. Life Sciences. 5: 465-71. PMID 4164142 DOI: 10.1016/0024-3205(66)90163-9 |
0.271 |
|
| 1966 |
Welch RM, Conney AH, Burns JJ. The metabolism of acetophenetidin and N-acetyl-p-aminophenol in the cat Biochemical Pharmacology. 15: 521-531. PMID 5961431 DOI: 10.1016/0006-2952(66)90018-9 |
0.337 |
|
| 1966 |
Conney AH, Jacobson M, Schneidman K, Kuntzman R. Induction of liver microsomal cortisol 6beta-hydroxylase by diphenylhydantoin or phenobarbital: an explanation for the increased excretion of 6-hydroxycortisol in humans treated with these drugs. Life Sciences. 4: 1091-8. PMID 5838511 DOI: 10.1016/0024-3205(65)90229-8 |
0.282 |
|
| 1966 |
Kuntzman R, Sansur M, Conney AH. Effect of drugs and insecticides on the anesthetic action of steroids. Endocrinology. 77: 952-4. PMID 4378901 DOI: 10.1210/ENDO-77-5-952 |
0.238 |
|
| 1965 |
Burns JJ, Conney AH. Enzyme Stimulation and Inhibition in the Metabolism of Drugs Proceedings of the Royal Society of Medicine. 58: 955-960. DOI: 10.1177/003591576505811P203 |
0.294 |
|
| 1965 |
Welch RM, Conney AH. A Simple Method for the Quantitative Determination of N-Acetyl-p-Aminophenol (APAP) in Urine Clinical Chemistry. 11: 1064-1067. DOI: 10.1093/CLINCHEM/11.12.1064 |
0.256 |
|
| 1963 |
Gilman AG, Conney AH. The induction of aminoazo dye N-demethylase in nonhepatic tissues by 3-methyIcholanthrene Biochemical Pharmacology. 12: 591-593. PMID 13947967 DOI: 10.1016/0006-2952(63)90139-4 |
0.611 |
|
| 1963 |
Burns JJ, Conney AH, Koster R. STIMULATORY EFFECT OF CHRONIC DRUG ADMINISTRATION ON DRUG-METABOLIZING ENZYMES IN LIVER MICROSOMES Annals of the New York Academy of Sciences. 104: 881-893. DOI: 10.1111/j.1749-6632.1963.tb57090.x |
0.286 |
|
| 1961 |
Conney A, Burns J. Metabolism of uridine diphosphate glucuronic acid by liver and kidney Biochimica Et Biophysica Acta. 54: 369-372. DOI: 10.1016/0006-3002(61)90384-5 |
0.288 |
|
| 1961 |
Conney A. 462 Discussion of the previous paper Biochemical Pharmacology. 8: 138. DOI: 10.1016/0006-2952(61)90652-9 |
0.173 |
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