Jason M. Kinchen, Ph.D. - Publications

Affiliations: 
2004 Stony Brook University, Stony Brook, NY, United States 
Area:
Genetics, Cell Biology

31/63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Neukomm LJ, Kinchen JM. SRGP-1 regulation, targets, and contribution to cell killing in C. elegans. Small Gtpases. 2: 177-181. PMID 21776421 DOI: 10.4161/Sgtp.2.3.16700  0.619
2014 Sendoel A, Maida S, Zheng X, Teo Y, Stergiou L, Rossi CA, Subasic D, Pinto SM, Kinchen JM, Shi M, Boettcher S, Meyer JN, Manz MG, Bano D, Hengartner MO. DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis. Nature Cell Biology. 16: 812-20. PMID 25064737 DOI: 10.1038/Ncb3010  0.624
2014 Coquery CM, Wade NS, Loo WM, Kinchen JM, Cox KM, Jiang C, Tung KS, Erickson LD. Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice. Plos One. 9: e102284. PMID 25010693 DOI: 10.1371/Journal.Pone.0102284  0.396
2014 Poon IK, Chiu YH, Armstrong AJ, Kinchen JM, Juncadella IJ, Bayliss DA, Ravichandran KS. Unexpected link between an antibiotic, pannexin channels and apoptosis. Nature. 507: 329-34. PMID 24646995 DOI: 10.1038/Nature13147  0.376
2013 Janisch KM, Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF, Dwyer ND. The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development (Cambridge, England). 140: 4672-82. PMID 24173802 DOI: 10.1242/Dev.093286  0.443
2013 Hochreiter-Hufford AE, Lee CS, Kinchen JM, Sokolowski JD, Arandjelovic S, Call JA, Klibanov AL, Yan Z, Mandell JW, Ravichandran KS. Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion. Nature. 497: 263-7. PMID 23615608 DOI: 10.1038/Nature12135  0.47
2011 Park D, Han CZ, Elliott MR, Kinchen JM, Trampont PC, Das S, Collins S, Lysiak JJ, Hoehn KL, Ravichandran KS. Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein. Nature. 477: 220-4. PMID 21857682 DOI: 10.1038/Nature10340  0.451
2011 Almendinger J, Doukoumetzidis K, Kinchen JM, Kaech A, Ravichandran KS, Hengartner MO. A conserved role for SNX9-family members in the regulation of phagosome maturation during engulfment of apoptotic cells. Plos One. 6: e18325. PMID 21494661 DOI: 10.1371/Journal.Pone.0018325  0.72
2011 Neukomm LJ, Nicot AS, Kinchen JM, Almendinger J, Pinto SM, Zeng S, Doukoumetzidis K, Tronchère H, Payrastre B, Laporte JF, Hengartner MO. The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans. Development (Cambridge, England). 138: 2003-14. PMID 21490059 DOI: 10.1242/Dev.060012  0.707
2011 Neukomm LJ, Frei AP, Cabello J, Kinchen JM, Zaidel-Bar R, Ma Z, Haney LB, Hardin J, Ravichandran KS, Moreno S, Hengartner MO. Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans. Nature Cell Biology. 13: 79-86. PMID 21170032 DOI: 10.1038/Ncb2138  0.71
2011 Sandilos JK, Chekeni FB, Elliott MR, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Ravichandran KS, Bayliss DA. Caspases Mediate Pannexin 1 Channel Activation in Apoptotic Cells Biophysical Journal. 100: 101a. DOI: 10.1016/J.Bpj.2010.12.759  0.518
2010 Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Bayliss DA, Ravichandran KS. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 467: 863-7. PMID 20944749 DOI: 10.1038/Nature09413  0.442
2010 Elliott MR, Zheng S, Park D, Woodson RI, Reardon MA, Juncadella IJ, Kinchen JM, Zhang J, Lysiak JJ, Ravichandran KS. Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo. Nature. 467: 333-7. PMID 20844538 DOI: 10.1038/Nature09356  0.589
2010 Kinchen JM. A model to die for: signaling to apoptotic cell removal in worm, fly and mouse. Apoptosis : An International Journal On Programmed Cell Death. 15: 998-1006. PMID 20461556 DOI: 10.1007/S10495-010-0509-5  0.532
2010 Kinchen JM, Ravichandran KS. Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells. Nature. 464: 778-82. PMID 20305638 DOI: 10.1038/Nature08853  0.57
2010 Brassinga AK, Kinchen JM, Cupp ME, Day SR, Hoffman PS, Sifri CD. Caenorhabditis is a metazoan host for Legionella. Cellular Microbiology. 12: 343-61. PMID 19863556 DOI: 10.1111/J.1462-5822.2009.01398.X  0.314
2009 Gronski MA, Kinchen JM, Juncadella IJ, Franc NC, Ravichandran KS. An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response. Cell Death and Differentiation. 16: 1323-31. PMID 19461656 DOI: 10.1038/Cdd.2009.55  0.493
2008 Kinchen JM, Ravichandran KS. Phagosome maturation: going through the acid test. Nature Reviews. Molecular Cell Biology. 9: 781-95. PMID 18813294 DOI: 10.1038/Nrm2515  0.409
2008 Kinchen JM, Ravichandran KS. Phagocytic signaling: you can touch, but you can't eat. Current Biology : Cb. 18: R521-4. PMID 18579095 DOI: 10.1016/J.Cub.2008.04.058  0.352
2008 Kinchen JM, Doukoumetzidis K, Almendinger J, Stergiou L, Tosello-Trampont A, Sifri CD, Hengartner MO, Ravichandran KS. A pathway for phagosome maturation during engulfment of apoptotic cells. Nature Cell Biology. 10: 556-66. PMID 18425118 DOI: 10.1038/Ncb1718  0.684
2007 Kinchen JM, Ravichandran KS. Journey to the grave: signaling events regulating removal of apoptotic cells. Journal of Cell Science. 120: 2143-9. PMID 17591687 DOI: 10.1242/Jcs.03463  0.561
2007 Tosello-Trampont AC, Kinchen JM, Brugnera E, Haney LB, Hengartner MO, Ravichandran KS. Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells. Cell Death and Differentiation. 14: 963-72. PMID 17304244 DOI: 10.1038/sj.cdd.4402094  0.67
2006 Grimsley CM, Lu M, Haney LB, Kinchen JM, Ravichandran KS. Characterization of a novel interaction between ELMO1 and ERM proteins. The Journal of Biological Chemistry. 281: 5928-37. PMID 16377631 DOI: 10.1074/Jbc.M510647200  0.427
2005 Kinchen JM, Cabello J, Klingele D, Wong K, Feichtinger R, Schnabel H, Schnabel R, Hengartner MO. Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans. Nature. 434: 93-9. PMID 15744306 DOI: 10.1038/Nature03263  0.701
2005 Lu M, Kinchen JM, Rossman KL, Grimsley C, Hall M, Sondek J, Hengartner MO, Yajnik V, Ravichandran KS. A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs. Current Biology : Cb. 15: 371-7. PMID 15723800 DOI: 10.1016/J.Cub.2005.01.050  0.577
2005 Kinchen JM, Hengartner MO. Tales of cannibalism, suicide, and murder: Programmed cell death in C. elegans. Current Topics in Developmental Biology. 65: 1-45. PMID 15642378 DOI: 10.1016/S0070-2153(04)65001-0  0.622
2004 deBakker CD, Haney LB, Kinchen JM, Grimsley C, Lu M, Klingele D, Hsu PK, Chou BK, Cheng LC, Blangy A, Sondek J, Hengartner MO, Wu YC, Ravichandran KS. Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO. Current Biology : Cb. 14: 2208-16. PMID 15620647 DOI: 10.1016/J.Cub.2004.12.029  0.702
2004 Hoeppner DJ, Spector MS, Ratliff TM, Kinchen JM, Granat S, Lin SC, Bhusri SS, Conradt B, Herman MA, Hengartner MO. eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans. Developmental Biology. 274: 125-38. PMID 15355793 DOI: 10.1016/J.Ydbio.2004.06.022  0.726
2004 Lu M, Kinchen JM, Rossman KL, Grimsley C, deBakker C, Brugnera E, Tosello-Trampont AC, Haney LB, Klingele D, Sondek J, Hengartner MO, Ravichandran KS. PH domain of ELMO functions in trans to regulate Rac activation via Dock180. Nature Structural & Molecular Biology. 11: 756-62. PMID 15247908 DOI: 10.1038/Nsmb800  0.572
2004 Grimsley CM, Kinchen JM, Tosello-Trampont AC, Brugnera E, Haney LB, Lu M, Chen Q, Klingele D, Hengartner MO, Ravichandran KS. Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration. The Journal of Biological Chemistry. 279: 6087-97. PMID 14638695 DOI: 10.1074/Jbc.M307087200  0.658
2001 Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107: 27-41. PMID 11595183 DOI: 10.1016/S0092-8674(01)00520-7  0.747
Low-probability matches (unlikely to be authored by this person)
2016 Han CZ, Juncadella IJ, Kinchen JM, Buckley MW, Klibanov AL, Dryden K, Onengut-Gumuscu S, Erdbrügger U, Turner SD, Shim YM, Tung KS, Ravichandran KS. Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation. Nature. PMID 27820945 DOI: 10.1038/nature20141  0.284
2019 Koronowski KB, Kinouchi K, Welz PS, Smith JG, Zinna VM, Shi J, Samad M, Chen S, Magnan CN, Kinchen JM, Li W, Baldi P, Benitah SA, Sassone-Corsi P. Defining the Independence of the Liver Circadian Clock. Cell. 177: 1448-1462.e14. PMID 31150621 DOI: 10.1016/J.Cell.2019.04.025  0.237
2021 Kinchen JM, Mohney RP, Pappan KL. Long-Chain Acylcholines Link Butyrylcholinesterase to Regulation of Non-neuronal Cholinergic Signaling. Journal of Proteome Research. PMID 34758617 DOI: 10.1021/acs.jproteome.1c00538  0.195
2021 Ravisankar S, Brooks KE, Murphy MJ, Redmayne N, Ryu J, Kinchen JM, Chavez SL, Hennebold JD. Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency. Scientific Reports. 11: 6506. PMID 33753762 DOI: 10.1038/s41598-021-85704-6  0.191
2017 Kamarajan P, Rajendiran TM, Kinchen J, Bermúdez M, Danciu T, Kapila YL. Head and Neck Squamous Cell Carcinoma Metabolism draws on Glutaminolysis, and Stemness is Specifically Regulated by Glutaminolysis via Aldehyde Dehydrogenase. Journal of Proteome Research. PMID 28168879 DOI: 10.1021/Acs.Jproteome.6B00936  0.177
2019 Yee SW, Stecula A, Chien HC, Zou L, Feofanova EV, van Borselen M, Cheung KWK, Yousri NA, Suhre K, Kinchen JM, Boerwinkle E, Irannejad R, Yu B, Giacomini KM. Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies. Plos Genetics. 15: e1008208. PMID 31553721 DOI: 10.1371/Journal.Pgen.1008208  0.175
2008 Sifri CD, Brassinga AK, Flohr T, Kinchen JM, Hazen KC, Sawyer RG, Pruett TL, Bonatti H. Moraxella osloensis bacteremia in a kidney transplant recipient. Transplant International : Official Journal of the European Society For Organ Transplantation. 21: 1011-3. PMID 18662367 DOI: 10.1111/J.1432-2277.2008.00727.X  0.165
2018 McKenna Iii J, Kapfhamer D, Kinchen JM, Wasek B, Dunworth M, Murray-Stewart T, Bottiglieri T, Casero RA, Gambello MJ. Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex. Human Molecular Genetics. PMID 29635516 DOI: 10.1093/Hmg/Ddy118  0.165
2016 Espinosa-Jeffrey A, Nguyen K, Kumar S, Toshimasa O, Hirose R, Reue K, Vergnes L, Kinchen J, Vellis J. Simulated microgravity enhances oligodendrocyte mitochondrial function and lipid metabolism. Journal of Neuroscience Research. PMID 27680492 DOI: 10.1002/Jnr.23958  0.146
2018 Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Charvet LY, Chandel NS, Schumacker PT, Thorp EB. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. Cell Metabolism. PMID 30595481 DOI: 10.1016/J.Cmet.2018.12.004  0.144
2016 Rafikova O, Meadows ML, Kinchen JM, Mohney RP, Maltepe E, Desai AA, Yuan JX, Garcia JG, Fineman JR, Rafikov R, Black SM. Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung. Plos One. 11: e0150480. PMID 26937637 DOI: 10.1371/journal.pone.0150480  0.115
2019 Wilinski D, Winzeler J, Duren W, Persons JL, Holme KJ, Mosquera J, Khabiri M, Kinchen JM, Freddolino PL, Karnovsky A, Dus M. Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster. Nature Communications. 10: 4052. PMID 31492856 DOI: 10.1038/S41467-019-11933-Z  0.092
2019 Divaris K, Shungin D, Rodríguez-Cortés A, Basta PV, Roach J, Cho H, Wu D, Ferreira Zandoná AG, Ginnis J, Ramamoorthy S, Kinchen JM, Kwintkiewicz J, Butz N, Ribeiro AA, Azcarate-Peril MA. The Supragingival Biofilm in Early Childhood Caries: Clinical and Laboratory Protocols and Bioinformatics Pipelines Supporting Metagenomics, Metatranscriptomics, and Metabolomics Studies of the Oral Microbiome. Methods in Molecular Biology (Clifton, N.J.). 1922: 525-548. PMID 30838598 DOI: 10.1007/978-1-4939-9012-2_40  0.087
2015 Zwart SR, Gregory JF, Zeisel SH, Gibson CR, Mader TH, Kinchen JM, Ueland PM, Ploutz-Snyder R, Heer MA, Smith SM. Genotype, B-vitamin status, and androgens affect spaceflight-induced ophthalmic changes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26316272 DOI: 10.1096/fj.15-278457  0.086
2016 Yee SW, Giacomini MM, Hsueh CH, Weitz D, Liang X, Goswami S, Kinchen JM, Coelho A, Zur AA, Mertsch K, Brian W, Kroetz DL, Giacomini KM. Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1. Clinical Pharmacology and Therapeutics. PMID 27447836 DOI: 10.1002/Cpt.434  0.083
2018 Bent S, Lawton B, Warren T, Widjaja F, Dang K, Fahey JW, Cornblatt B, Kinchen JM, Delucchi K, Hendren RL. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Molecular Autism. 9: 35. PMID 29854372 DOI: 10.1186/s13229-018-0218-4  0.08
2017 Asquith M, Davin S, Stauffer P, Michell C, Janowitz C, Lin P, Ensign-Lewis J, Kinchen JM, Koop DR, Rosenbaum J. Intestinal metabolites are profoundly altered in the context of HLA-B27 expression and functionally modulate disease in a rat model of spondyloarthropathy. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28622455 DOI: 10.1002/Art.40183  0.08
2020 Razavi AC, Bazzano LA, He J, Whelton SP, Rebholz CM, Fernandez C, Krousel-Woods M, Li C, Shi M, Nierenberg JL, Li S, Kinchen J, Mi X, Kelly TN. Race modifies the association between animal protein metabolite 1-methylhistidine and blood pressure in middle-aged adults: the Bogalusa Heart Study. Journal of Hypertension. PMID 32649643 DOI: 10.1097/HJH.0000000000002571  0.074
2019 Nierenberg JL, He J, Li C, Gu X, Shi M, Razavi AC, Mi X, Li S, Bazzano LA, Anderson AH, He H, Chen W, Kinchen JM, Rebholz CM, Coresh J, et al. Novel associations between blood metabolites and kidney function among Bogalusa Heart Study and Multi-Ethnic Study of Atherosclerosis participants. Metabolomics : Official Journal of the Metabolomic Society. 15: 149. PMID 31720858 DOI: 10.1007/S11306-019-1613-3  0.074
2016 Ilievski V, Kinchen JM, Prabhu R, Rim F, Leoni L, Unterman TG, Watanabe K. Experimental Periodontitis Results in Prediabetes and Metabolic Alterations in Brain, Liver and Heart: Global Untargeted Metabolomic Analyses. Journal of Oral Biology (Northborough, Mass.). 3. PMID 27390783  0.072
2020 Razavi AC, Bazzano LA, He J, Fernandez C, Whelton SP, Krousel-Wood M, Li S, Nierenberg JL, Shi M, Li C, Mi X, Kinchen J, Kelly TN. Novel Findings From a Metabolomics Study of Left Ventricular Diastolic Function: The Bogalusa Heart Study. Journal of the American Heart Association. 9: e015118. PMID 31992159 DOI: 10.1161/JAHA.119.015118  0.066
2019 Shi M, Bazzano LA, He J, Gu X, Li C, Li S, Yaffe K, Kinchen JM, Stuchlik P, Mi X, Nierenberg JL, Razavi AC, Kelly TN. Novel serum metabolites associate with cognition phenotypes among Bogalusa Heart Study participants. Aging. PMID 31327759 DOI: 10.18632/aging.102107  0.063
2018 Wone BWM, Kinchen JM, Kaup ER, Wone B. A procession of metabolic alterations accompanying muscle senescence in Manduca sexta. Scientific Reports. 8: 1006. PMID 29343811 DOI: 10.1038/S41598-018-19630-5  0.062
2021 Ravisankar S, Hanna CB, Brooks KE, Murphy MJ, Redmayne N, Ryu J, Kinchen JM, Chavez SL, Hennebold JD. Author Correction: Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency. Scientific Reports. 11: 16968. PMID 34400753 DOI: 10.1038/s41598-021-96473-7  0.06
2016 Saito K, Maekawa K, Kinchen JM, Tanaka R, Kumagai Y, Saito Y. Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations. Biological & Pharmaceutical Bulletin. 39: 1179-86. PMID 27374292 DOI: 10.1248/bpb.b16-00226  0.056
2020 Nierenberg JL, He J, Li C, Gu X, Shi M, Razavi AC, Mi X, Li S, Bazzano LA, Anderson AH, He H, Chen W, Guralnik JM, Kinchen JM, Kelly TN. Serum metabolites associate with physical performance among middle-aged adults: Evidence from the Bogalusa Heart Study. Aging. 12. PMID 32482911 DOI: 10.18632/aging.103362  0.051
2020 Gu X, Li C, He J, Li S, Bazzano LA, Kinchen JM, Chen W, He H, Gu D, Kelly TN. Serum metabolites associate with lipid phenotypes among Bogalusa Heart Study participants. Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd. PMID 32131987 DOI: 10.1016/j.numecd.2020.01.004  0.051
2021 Kordy K, Li F, Lee DJ, Kinchen JM, Jew MH, La Rocque ME, Zabih S, Saavedra M, Woodward C, Cunningham NJ, Tobin NH, Aldrovandi GM. Metabolomic Predictors of Non-alcoholic Steatohepatitis and Advanced Fibrosis in Children. Frontiers in Microbiology. 12: 713234. PMID 34475864 DOI: 10.3389/fmicb.2021.713234  0.05
2016 Luo T, Miranda-Garcia O, Adamson A, Hamilton-Reeves J, Sullivan DK, Kinchen JM, Shay NF. Consumption of Walnuts in Combination with Other Whole Foods Produces Physiologic, Metabolic, and Gene Expression Changes in Obese C57BL/6J High-Fat-Fed Male Mice. The Journal of Nutrition. PMID 27489005 DOI: 10.3945/Jn.116.234419  0.046
2020 Razavi AC, Bazzano LAA, He J, Li S, Fernandez C, Whelton SP, Krousel-Wood M, Nierenberg JL, Shi M, Li C, Mi X, Kinchen J, Kelly TN. Pseudouridine and N-formylmethionine associate with left ventricular mass index: Metabolome-wide association analysis of cardiac remodeling. Journal of Molecular and Cellular Cardiology. PMID 32057737 DOI: 10.1016/j.yjmcc.2020.02.005  0.04
2015 Nieman DC, Gillitt ND, Sha W, Meaney MP, John C, Pappan KL, Kinchen JM. Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery. Journal of Proteome Research. PMID 26561314 DOI: 10.1021/Acs.Jproteome.5B00909  0.033
2018 Sun T, Lee B, Kinchen J, Wang ET, Gonzalez TL, Chan JL, Rotter JI, Chen YI, Taylor K, Goodarzi MO, Rich SS, Farber CR, Williams J, Pisarska MD. Differences in First Trimester Maternal Metabolomic Profiles in Pregnancies Conceived from Fertility Treatments. The Journal of Clinical Endocrinology and Metabolism. PMID 30445606 DOI: 10.1210/Jc.2018-01118  0.011
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