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Justin L. Mott, Ph.D. - Publications

Affiliations: 
2003 Saint Louis University, St. Louis, MO, United States 
Area:
Animal Physiology Biology, Cell Biology, Molecular Biology
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Natarajan SK, Muthukrishnan E, Khalimonchuk O, Mott JL, Becker DF. Evidence for Pipecolate Oxidase in Mediating Protection Against Hydrogen Peroxide Stress. Journal of Cellular Biochemistry. PMID 27922192 DOI: 10.1002/Jcb.25825  0.332
2016 Lu S, Natarajan SK, Mott JL, Kharbanda KK, Harrison-Findik DD. Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. Plos One. 11: e0147474. PMID 26807955 DOI: 10.1371/Journal.Pone.0147474  0.34
2014 Miyamoto Y, Mauer AS, Kumar S, Mott JL, Malhi H. Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. Plos One. 9: e109637. PMID 25314137 DOI: 10.1371/Journal.Pone.0109637  0.301
2014 Natarajan SK, Ingham SA, Mohr AM, Wehrkamp CJ, Ray A, Roy S, Cazanave SC, Phillippi MA, Mott JL. Saturated free fatty acids induce cholangiocyte lipoapoptosis. Hepatology (Baltimore, Md.). 60: 1942-56. PMID 24753158 DOI: 10.1002/Hep.27175  0.374
2014 Wehrkamp CJ, Gutwein AR, Natarajan SK, Phillippi MA, Mott JL. XIAP antagonist embelin inhibited proliferation of cholangiocarcinoma cells. Plos One. 9: e90238. PMID 24603802 DOI: 10.1371/Journal.Pone.0090238  0.408
2013 Guicciardi ME, Malhi H, Mott JL, Gores GJ. Apoptosis and necrosis in the liver. Comprehensive Physiology. 3: 977-1010. PMID 23720337 DOI: 10.1002/Cphy.C120020  0.37
2012 Gupta S, Read DE, Deepti A, Cawley K, Gupta A, Oommen D, Verfaillie T, Matus S, Smith MA, Mott JL, Agostinis P, Hetz C, Samali A. Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis. Cell Death & Disease. 3: e333. PMID 22739985 DOI: 10.1038/Cddis.2012.74  0.332
2012 Kakisaka K, Cazanave SC, Fingas CD, Guicciardi ME, Bronk SF, Werneburg NW, Mott JL, Gores GJ. Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G77-84. PMID 21995961 DOI: 10.1152/Ajpgi.00301.2011  0.372
2012 Razumilava N, Bronk SF, Smoot RL, Fingas CD, Werneburg NW, Roberts LR, Mott JL. miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma. Hepatology (Baltimore, Md.). 55: 465-75. PMID 21953056 DOI: 10.1002/Hep.24698  0.335
2012 Mertens JC, Fingas CD, Christensen JD, Kakisaka K, Smoot RL, Bronk SF, Mott JL, Gustafson MP, Dietz AB, Roberts LR, Sirica AE, Gores GJ. Abstract 4905: The BH3 mimetic navitoclax (ABT-263) selectively induces apoptosis in cholangiocarcinoma-associated fibroblasts thereby reducing tumor growth Cancer Research. 72: 4905-4905. DOI: 10.1158/1538-7445.Am2012-4905  0.336
2011 Fingas CD, Bronk SF, Werneburg NW, Mott JL, Guicciardi ME, Cazanave SC, Mertens JC, Sirica AE, Gores GJ. Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells. Hepatology (Baltimore, Md.). 54: 2076-88. PMID 22038837 DOI: 10.1002/Hep.24588  0.371
2011 Cazanave SC, Mott JL, Bronk SF, Werneburg NW, Fingas CD, Meng XW, Finnberg N, El-Deiry WS, Kaufmann SH, Gores GJ. Death receptor 5 signaling promotes hepatocyte lipoapoptosis. The Journal of Biological Chemistry. 286: 39336-48. PMID 21941003 DOI: 10.1074/Jbc.M111.280420  0.382
2011 Kurita S, Mott JL, Cazanave SC, Fingas CD, Guicciardi ME, Bronk SF, Roberts LR, Fernandez-Zapico ME, Gores GJ. Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells. Plos One. 6: e18330. PMID 21483830 DOI: 10.1371/Journal.Pone.0018330  0.41
2011 Guicciardi ME, Mott JL, Bronk SF, Kurita S, Fingas CD, Gores GJ. Cellular inhibitor of apoptosis 1 (cIAP-1) degradation by caspase 8 during TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. Experimental Cell Research. 317: 107-16. PMID 20951133 DOI: 10.1016/J.Yexcr.2010.10.005  0.402
2011 Kurita S, Mott JL, Fernandez-Zapico ME, Bronk SF, Guicciardi ME, Roberts LR, Hibi T, Gores GJ. Abstract 4105: Hedgehog inhibition promotes type I TRAIL cytotoxicity in human cholangiocarcinoma cells Cancer Research. 71: 4105-4105. DOI: 10.1158/1538-7445.Am2011-4105  0.409
2011 Razumilava N, Smoot RL, Bronk SF, Gores GJ, Mott JL. Abstract 199: Regulation of apoptosis in cholangiocarcinoma by miR-106b∼25 cluster Cancer Research. 71: 199-199. DOI: 10.1158/1538-7445.Am2011-199  0.335
2010 Fingas CD, Blechacz BR, Smoot RL, Guicciardi ME, Mott J, Bronk SF, Werneburg NW, Sirica AE, Gores GJ. A smac mimetic reduces TNF related apoptosis inducing ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells. Hepatology (Baltimore, Md.). 52: 550-61. PMID 20683954 DOI: 10.1002/Hep.23729  0.392
2010 Kurita S, Mott JL, Almada LL, Bronk SF, Werneburg NW, Sun SY, Roberts LR, Fernandez-Zapico ME, Gores GJ. GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis. Oncogene. 29: 4848-58. PMID 20562908 DOI: 10.1038/Onc.2010.235  0.377
2010 Sosa Seda IM, Mott JL, Akazawa Y, Barreyro FJ, Bronk SF, Kaufmann SH, Gores GJ. Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 40: 701-10. PMID 20557369 DOI: 10.1111/J.1872-034X.2010.00668.X  0.378
2010 Cazanave SC, Elmi NA, Akazawa Y, Bronk SF, Mott JL, Gores GJ. CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G236-43. PMID 20430872 DOI: 10.1152/Ajpgi.00091.2010  0.364
2010 Akazawa Y, Cazanave S, Mott JL, Elmi N, Bronk SF, Kohno S, Charlton MR, Gores GJ. Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. Journal of Hepatology. 52: 586-93. PMID 20206402 DOI: 10.1016/J.Jhep.2010.01.003  0.372
2009 Masuoka HC, Mott J, Bronk SF, Werneburg NW, Akazawa Y, Kaufmann SH, Gores GJ. Mcl-1 degradation during hepatocyte lipoapoptosis. The Journal of Biological Chemistry. 284: 30039-48. PMID 19734538 DOI: 10.1074/Jbc.M109.039545  0.326
2009 Cazanave SC, Mott JL, Elmi NA, Bronk SF, Werneburg NW, Akazawa Y, Kahraman A, Garrison SP, Zambetti GP, Charlton MR, Gores GJ. JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis. The Journal of Biological Chemistry. 284: 26591-602. PMID 19638343 DOI: 10.1074/Jbc.M109.022491  0.361
2009 Mott JL. MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia. Hepatology (Baltimore, Md.). 50: 630-7. PMID 19585622 DOI: 10.1002/Hep.23010  0.315
2009 Akazawa Y, Mott JL, Bronk SF, Werneburg NW, Kahraman A, Guicciardi ME, Meng XW, Kohno S, Shah VH, Kaufmann SH, McNiven MA, Gores GJ. Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines. Gastroenterology. 136: 2365-2376.e1-7. PMID 19272388 DOI: 10.1053/J.Gastro.2009.02.071  0.36
2009 Bensch KG, Mott JL, Chang SW, Hansen PA, Moxley MA, Chambers KT, de Graaf W, Zassenhaus HP, Corbett JA. Selective mtDNA mutation accumulation results in beta-cell apoptosis and diabetes development. American Journal of Physiology. Endocrinology and Metabolism. 296: E672-80. PMID 19158322 DOI: 10.1152/Ajpendo.90839.2008  0.667
2009 Kahraman A, Mott JL, Bronk SF, Werneburg NW, Barreyro FJ, Guicciardi ME, Akazawa Y, Braley K, Craig RW, Gores GJ. Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse. Digestive Diseases and Sciences. 54: 1908-17. PMID 19051025 DOI: 10.1007/S10620-008-0583-5  0.308
2009 Akazawa Y, Mott JL, Bronk SF, Werneburg NW, Guicciardi ME, Meng X, McNiven MA, Gores GJ. 5 Rab7 Dependent DR5 Trafficking to Lysosomes Is Required for the Lysosomal Pathway of TRAIL Mediated Apoptosis Gastroenterology. 136: A-789-A-790. DOI: 10.1016/S0016-5085(09)63643-X  0.353
2008 Mott JL, Bronk SF, Mesa RA, Kaufmann SH, Gores GJ. BH3-only protein mimetic obatoclax sensitizes cholangiocarcinoma cells to Apo2L/TRAIL-induced apoptosis. Molecular Cancer Therapeutics. 7: 2339-47. PMID 18723481 DOI: 10.1158/1535-7163.Mct-08-0285  0.393
2008 Sosa Seda IM, Mott JL, Barreyro FJ, Akazawa Y, Kahraman A, Bronk SF, Werneburg NW, Gores GJ. 365 The Bh3-Only Protein Noxa Mediates Hepatic Stellate Cell Apoptosis By Proteasome Inhibition Gastroenterology. 134: A-764. DOI: 10.1016/S0016-5085(08)63571-4  0.355
2007 Kobayashi S, Lee SH, Meng XW, Mott JL, Bronk SF, Werneburg NW, Craig RW, Kaufmann SH, Gores GJ. Serine 64 phosphorylation enhances the antiapoptotic function of Mcl-1. The Journal of Biological Chemistry. 282: 18407-17. PMID 17463001 DOI: 10.1074/Jbc.M610010200  0.308
2007 Mott JL, Kobayashi S, Bronk SF, Gores GJ. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene. 26: 6133-40. PMID 17404574 DOI: 10.1038/Sj.Onc.1210436  0.32
2006 Mott JL, Zhang D, Chang SW, Zassenhaus HP. Mitochondrial DNA mutations cause resistance to opening of the permeability transition pore. Biochimica Et Biophysica Acta. 1757: 596-603. PMID 16829230 DOI: 10.1016/J.Bbabio.2006.04.014  0.733
2006 Yoshida M, Michel H, Sazanov L, Yoshikawa S, Barber J, Lanyi J, Balashov S, Shuvalov V, Yakovlev A, Shkuropatova T, Vasilieva L, Shkuropatov A, Gast P, Dunn S, Del Rizzo P, ... ... Mott J, et al. MITCHELL MEDAL LECTURE Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1757: 1-551. DOI: 10.1016/j.bbabio.2006.06.009  0.547
2005 Mott JL, Zhang D, Zassenhaus HP. Mitochondrial DNA mutations, apoptosis, and the misfolded protein response. Rejuvenation Research. 8: 216-26. PMID 16313221 DOI: 10.1089/Rej.2005.8.216  0.736
2005 Zhang D, Mott JL, Chang SW, Stevens M, Mikolajczak P, Zassenhaus HP. Mitochondrial DNA mutations activate programmed cell survival in the mouse heart. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2476-83. PMID 15840907 DOI: 10.1152/Ajpheart.00670.2004  0.737
2004 Mott JL, Zhang D, Freeman JC, Mikolajczak P, Chang SW, Zassenhaus HP. Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A. Biochemical and Biophysical Research Communications. 319: 1210-5. PMID 15194495 DOI: 10.1016/J.Bbrc.2004.05.104  0.738
2003 Zhang D, Mott JL, Farrar P, Ryerse JS, Chang SW, Stevens M, Denniger G, Zassenhaus HP. Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy. Cardiovascular Research. 57: 147-57. PMID 12504824 DOI: 10.1016/S0008-6363(02)00695-8  0.721
2001 Zhang D, Mott JL, Zassenhaus HP. Chronic Apoptotic Signaling is Induced by Low Levels of Mitochondrial Dna Mutations in the Mouse Heart. Thescientificworldjournal. 1: 59. PMID 30147528 DOI: 10.1100/Tsw.2001.177  0.736
2001 Mott JL, Zhang D, Stevens M, Chang S, Denniger G, Zassenhaus HP. Oxidative stress is not an obligate mediator of disease provoked by mitochondrial DNA mutations. Mutation Research. 474: 35-45. PMID 11239961 DOI: 10.1016/S0027-5107(00)00159-7  0.721
2000 Mott JL, Denniger G, Zullo SJ, Zassenhaus HP. Genomic structure of murine mitochondrial DNA polymerase-gamma. Dna and Cell Biology. 19: 601-5. PMID 11058962 DOI: 10.1089/104454900750019353  0.657
2000 Zhang D, Mott JL, Chang SW, Denniger G, Feng Z, Zassenhaus HP. Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis. Genomics. 69: 151-61. PMID 11031098 DOI: 10.1006/Geno.2000.6333  0.72
1999 Mott JL, Zhang D, Farrar PL, Chang SW, Zassenhaus HP. Low frequencies of mitochondrial DNA mutations cause cardiac disease in the mouse. Annals of the New York Academy of Sciences. 893: 353-7. PMID 10672265 DOI: 10.1111/J.1749-6632.1999.Tb07853.X  0.705
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