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Laura M. Lashinger, Ph.D. - Publications

Affiliations: 
2005 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology, Molecular Biology, Oncology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Coleman M, Liu K, Tang X, Lashinger L, Cui Z, Hursting S. Dietary β-Hydroxy-β-Methylbutyrate Supplementation Promotes PDAC Response to Gemcitabine and Immunotherapy Response in Obese Mice Current Developments in Nutrition. 4: 313-313. DOI: 10.1093/cdn/nzaa044_012  0.309
2019 Coleman MF, Liu KA, Tang X, Fabela S, Lashinger LM, Cui Z, Hursting SD. Abstract 1090: β-Hydroxy-β-Methylbutyrate supplementation preserves muscle mass and reduces tumor growth in obese mice Cancer Research. 79: 1090-1090. DOI: 10.1158/1538-7445.Am2019-1090  0.387
2016 Lashinger LM, O'Flanagan CH, Dunlap SM, Rasmussen AJ, Sweeney S, Guo JY, Lodi A, Tiziani S, White E, Hursting SD. Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors. Cancer & Metabolism. 4: 18. PMID 27651895 DOI: 10.1186/S40170-016-0158-4  0.49
2016 Devlin KL, Sanford T, Harrison LM, LeBourgeois P, Lashinger LM, Mambo E, Hursting SD. Stage-Specific MicroRNAs and Their Role in the Anticancer Effects of Calorie Restriction in a Rat Model of ER-Positive Luminal Breast Cancer. Plos One. 11: e0159686. PMID 27433802 DOI: 10.1371/Journal.Pone.0159686  0.337
2016 Naguib YW, Lansakara-P D, Lashinger LM, Rodriguez BL, Valdes S, Niu M, Aldayel AM, Peng L, Hursting SD, Cui Z. Synthesis, Characterization, and In Vitro and In Vivo Evaluations of 4-(N)-Docosahexaenoyl 2', 2'-Difluorodeoxycytidine with Potent and Broad-Spectrum Antitumor Activity. Neoplasia (New York, N.Y.). 18: 33-48. PMID 26806350 DOI: 10.1016/J.Neo.2015.11.012  0.509
2015 Cifarelli V, Lashinger LM, Devlin KL, Dunlap SM, Huang J, Kaaks R, Pollak MN, Hursting SD. Metformin and Rapamycin Reduce Pancreatic Cancer Growth in Obese Prediabetic Mice by Distinct MicroRNA-Regulated Mechanisms. Diabetes. 64: 1632-42. PMID 25576058 DOI: 10.2337/Db14-1132  0.441
2014 Lashinger LM, Rossi EL, Hursting SD. Obesity and resistance to cancer chemotherapy: interacting roles of inflammation and metabolic dysregulation. Clinical Pharmacology and Therapeutics. 96: 458-63. PMID 24960521 DOI: 10.1038/Clpt.2014.136  0.326
2014 Harvey AE, Lashinger LM, Hays D, Harrison LM, Lewis K, Fischer SM, Hursting SD. Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner. Plos One. 9: e94151. PMID 24804677 DOI: 10.1371/Journal.Pone.0094151  0.464
2014 Liu KA, Lashinger LM, Rasmussen AJ, Hursting SD. Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice. Cancer & Metabolism. 2: 6. PMID 24685128 DOI: 10.1186/2049-3002-2-6  0.462
2014 Lashinger LM, Ford NA, Hursting SD. Interacting inflammatory and growth factor signals underlie the obesity-cancer link. The Journal of Nutrition. 144: 109-13. PMID 24285690 DOI: 10.3945/Jn.113.178533  0.326
2013 Hursting SD, Dunlap SM, Ford NA, Hursting MJ, Lashinger LM. Calorie restriction and cancer prevention: a mechanistic perspective. Cancer & Metabolism. 1: 10. PMID 24280167 DOI: 10.1186/2049-3002-1-10  0.426
2013 Ford NA, Devlin KL, Lashinger LM, Hursting SD. Deconvoluting the obesity and breast cancer link: secretome, soil and seed interactions. Journal of Mammary Gland Biology and Neoplasia. 18: 267-75. PMID 24091864 DOI: 10.1007/S10911-013-9301-9  0.387
2013 Lashinger LM, Harrison LM, Rasmussen AJ, Logsdon CD, Fischer SM, McArthur MJ, Hursting SD. Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I. Cancer Prevention Research (Philadelphia, Pa.). 6: 1046-55. PMID 23980075 DOI: 10.1158/1940-6207.Capr-13-0185  0.428
2013 Ford NA, Lashinger LM, Allott EH, Hursting SD. Mechanistic targets and phytochemical strategies for breaking the obesity-cancer link. Frontiers in Oncology. 3: 209. PMID 23967401 DOI: 10.3389/Fonc.2013.00209  0.324
2013 Harvey AE, Lashinger LM, Otto G, Nunez NP, Hursting SD. Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression Molecular Carcinogenesis. 52: 997-1006. PMID 22778026 DOI: 10.1002/Mc.21940  0.449
2013 Lashinger LM, Harrison LM, Rasmussen AJ, Logsdon CD, Fischer SM, McArthur MJ, Hursting SD. Abstract LB-187: Dietary energy balance modulation of Kras- and Ink4a/Arf+/-driven pancreatic cancer: the role of insulin-like growth factor-1. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-187  0.429
2013 Rossi E, Ford N, Pruski M, Lashinger L, Hursting S. Abstract P2-05-07: Resveratrol blocks the protumorigenic effects of obesity in a postmenopausal breast cancer model Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P2-05-07  0.428
2012 Lashinger LM, Harrison LM, Rasmussen AJ, Hursting SD. Abstract 592: Dietary energy balance impacts spontaneous development of pancreatic ductal adenocarcinoma in the KrasG12D/INK4A transgenic model of pancreatic cancer Cancer Research. 72: 592-592. DOI: 10.1158/1538-7445.Am2012-592  0.399
2012 Dunlap SM, Lashinger LM, White E, Hursting SD. Abstract 4104: Moderate calorie restriction activates autophagy during tumor growth suppression Cancer Research. 72: 4104-4104. DOI: 10.1158/1538-7445.Am2012-4104  0.566
2011 Harvey AE, Lashinger LM, Hursting SD. The growing challenge of obesity and cancer: an inflammatory issue. Annals of the New York Academy of Sciences. 1229: 45-52. PMID 21793838 DOI: 10.1111/J.1749-6632.2011.06096.X  0.341
2011 Lashinger LM, Malone LM, Brown GW, Daniels EA, Goldberg JA, Otto G, Fischer SM, Hursting SD. Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer. Cancer Prevention Research (Philadelphia, Pa.). 4: 1041-51. PMID 21593197 DOI: 10.1158/1940-6207.Capr-11-0023  0.403
2011 Lashinger LM, Malone LM, McArthur MJ, Goldberg JA, Daniels EA, Pavone A, Colby JK, Smith NC, Perkins SN, Fischer SM, Hursting SD. Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia. Cancer Prevention Research (Philadelphia, Pa.). 4: 1030-40. PMID 21593196 DOI: 10.1158/1940-6207.Capr-11-0027  0.437
2011 Lashinger LM, Rasmussen AJ, Malone L, Hursting SD. Abstract 809: Dietary L-Leucine diminishes protective effects of calorie restriction in a transplant model of pancreatic cancer Cancer Research. 71: 809-809. DOI: 10.1158/1538-7445.Am2011-809  0.345
2010 Metwalli AR, Khanbolooki S, Jinesh G, Sundi D, Shah JB, Shrader M, Choi W, Lashinger LM, Chunduru S, McConkey DJ, McKinlay M, Kamat AM. Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells. Cancer Biology & Therapy. 10: 885-92. PMID 20814238 DOI: 10.4161/Cbt.10.9.13237  0.635
2010 Hursting SD, Smith SM, Lashinger LM, Harvey AE, Perkins SN. Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis. 31: 83-9. PMID 19969554 DOI: 10.1093/Carcin/Bgp280  0.369
2010 Lashinger LM, Malone L, Perkins SN, Colby JKL, Fischer SM, Hursting SD. Abstract A102: Genetic reduction of circulating IGF-1 decreases growth of pancreatic tumors in an orthotopic transplant model Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-A102  0.466
2010 Harvey AE, Lashinger LM, Malone LM, Perkins SN, Hursting SD. Abstract 4100: The anticancer effects of calorie restriction on Panc 02 pancreatic tumors are associated with decreased activation of NF-kB Cancer Research. 70: 4100-4100. DOI: 10.1158/1538-7445.Am10-4100  0.478
2010 Lashinger LM, Malone L, Perkins SN, Colby JK, Fischer SM, Hursting SD. Abstract 2883: Genetic reduction of circulating IGF-1 inhibits growth of COX-2- and Kras-induced pancreatic tumors in orthotopic transplant models Cancer Research. 70: 2883-2883. DOI: 10.1158/1538-7445.Am10-2883  0.482
2008 Lashinger L, Malone L, Daniels E, Smith N, Pavone A, Colby JK, Perkins S, Fischer SM, Hursting SD. Reduced levels of IGF-1 decrease tumor burden in an orthotopic mouse model of pancreatic cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 1504. PMID 27948318 DOI: 10.1200/jco.2008.26.15_suppl.1504  0.371
2008 Hursting SD, Lashinger LM, Wheatley KW, Rogers CJ, Colbert LH, Nunez NP, Perkins SN. Reducing the weight of cancer: mechanistic targets for breaking the obesity-carcinogenesis link. Best Practice & Research. Clinical Endocrinology & Metabolism. 22: 659-69. PMID 18971125 DOI: 10.1016/J.Beem.2008.08.009  0.374
2008 Lashinger LM, Malone L, Daniels E, Smith NC, Pavone A, Colby JL, Fischer SM, Hursting SD. Abstract 4188: Dietary energy balance impacts spontaneous pancreatic lesions in the K5.COX-2 transgenic model of pancreatic cancer Prevention and Research. DOI: 10.1158/1538-7445.Am2008-4188  0.304
2007 Hursting SD, Lashinger LM, Colbert LH, Rogers CJ, Wheatley KW, Nunez NP, Mahabir S, Barrett JC, Forman MR, Perkins SN. Energy balance and carcinogenesis: underlying pathways and targets for intervention. Current Cancer Drug Targets. 7: 484-91. PMID 17691908 DOI: 10.2174/156800907781386623  0.35
2007 Shrader M, Pino MS, Lashinger L, Bar-Eli M, Adam L, Dinney CP, McConkey DJ. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Research. 67: 1430-5. PMID 17308080 DOI: 10.1158/0008-5472.Can-06-1224  0.79
2005 Lashinger LM, Zhu K, Williams SA, Shrader M, Dinney CP, McConkey DJ. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. Cancer Research. 65: 4902-8. PMID 15930312 DOI: 10.1158/0008-5472.Can-04-3701  0.723
2004 Papageorgiou A, Lashinger L, Millikan R, Grossman HB, Benedict W, Dinney CP, McConkey DJ. Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells. Cancer Research. 64: 8973-9. PMID 15604261 DOI: 10.1158/0008-5472.Can-04-1909  0.729
2004 Raut CP, Nawrocki S, Lashinger LM, Davis DW, Khanbolooki S, Xiong H, Ellis LM, McConkey DJ. Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts. Cancer Biology & Therapy. 3: 1217-24. PMID 15477758 DOI: 10.4161/Cbt.3.12.1221  0.666
2004 Kamat AM, Karashima T, Davis DW, Lashinger L, Bar-Eli M, Millikan R, Shen Y, Dinney CP, McConkey DJ. The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo. Molecular Cancer Therapeutics. 3: 279-90. PMID 15026548  0.635
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