Fievos L. Christofi - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Schneider R, Miesen A, Lysson M, Schneiker B, Kalff JC, Müller CE, Christofi FL, Wehner S. Su1318 – P2X2 Receptor Signaling Induces Enteric Glia Activation in Murine Postoperative Ileus Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)38243-5  0.333
2018 Christofi FL. TRPV1 Sensory Neurons and Enteric Glia in ENS Link Tachykinins to Neuroinflammation and Nociception. Cellular and Molecular Gastroenterology and Hepatology. 6: 354-355. PMID 30182048 DOI: 10.1016/J.Jcmgh.2018.06.011  0.307
2018 Schneider R, Miesen A, Schneiker B, Lysson M, Christofi FL, Wehner S. Mo1590 - Purinergic Signaling in Enteric Glia Cells During Inflammation Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)32641-6  0.315
2017 Burnstock G, Jacobson KA, Christofi FL. Purinergic drug targets for gastrointestinal disorders. Current Opinion in Pharmacology. 37: 131-141. PMID 29149731 DOI: 10.1016/J.Coph.2017.10.011  0.388
2017 Liñán-Rico A, Ochoa-Cortes F, Zuleta-Alarcon A, Alhaj M, Tili E, Enneking J, Harzman A, Grants I, Bergese S, Christofi FL. UTP – Gated Signaling Pathways of 5-HT Release from BON Cells as a Model of Human Enterochromaffin Cells Frontiers in Pharmacology. 8: 429-429. PMID 28751862 DOI: 10.3389/Fphar.2017.00429  0.334
2017 Rico AL, Zuleta-Alarcon A, Ochoa-Cortes F, Grants I, Harzman A, Bergese SD, Christofi FL. UTP is a Potential Physiological Regulator of Human Enteric Glial Cell Communication by Activating P2Y4 and P2Y6 Receptors Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30913-7  0.334
2016 Linan-Rico A, Ochoa-Cortes F, Beyder A, Soghomonyan S, Zuleta-Alarcon A, Coppola V, Christofi FL. Mechanosensory Signaling in Enterochromaffin Cells and 5-HT Release: Potential Implications for Gut Inflammation. Frontiers in Neuroscience. 10: 564. PMID 28066160 DOI: 10.3389/Fnins.2016.00564  0.36
2016 Liñán-Rico A, Turco F, Ochoa-Cortes F, Harzman A, Needleman BJ, Arsenescu R, Abdel-Rasoul M, Fadda P, Grants I, Whitaker E, Cuomo R, Christofi FL. Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders. Inflammatory Bowel Diseases. 22: 1812-1834. PMID 27416040 DOI: 10.1097/Mib.0000000000000854  0.33
2016 Ochoa-Cortes F, Turco F, Linan-Rico A, Soghomonyan S, Whitaker E, Wehner S, Cuomo R, Christofi FL. Enteric Glial Cells: A New Frontier in Neurogastroenterology and Clinical Target for Inflammatory Bowel Diseases. Inflammatory Bowel Diseases. 22: 433-49. PMID 26689598 DOI: 10.1097/Mib.0000000000000667  0.351
2016 Ochoa-Cortes F, Rico AL, Zuleta-Alarcon A, Zhou M, Grants I, Needleman BJ, Harzman A, Cuomo R, Turco F, Christofi FL. Sa1689 Hemichannels, GJICs and ATP Signaling in Human Enteric Glial Cells (hEGC) Gastroenterology. 150: S346-S347. DOI: 10.1016/S0016-5085(16)31218-5  0.326
2016 Rico AL, Turco F, Ochoa-Cortes F, Harzman A, Arsenescu R, Abdel-Rasoul M, Fadda P, Grants I, Cuomo R, Christofi FL. Sa1683 Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for Intestinal Infections, Motility and IBD Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)31212-4  0.329
2016 Ochoa-Cortes F, Rico AL, Zuleta-Alarcon A, Zhou M, Whitaker E, Grants I, Mutafova-Yambolieva VN, Durnin L, Needleman BJ, Harzman A, Cuomo R, Turco F, Christofi FL. Sa1682 Mechanosensory Signaling in Human Enteric Glial Cells Gastroenterology. 150: S345. DOI: 10.1016/S0016-5085(16)31211-2  0.322
2015 Liñán-Rico A, Wunderlich JE, Enneking JT, Tso DR, Grants I, Williams KC, Otey A, Michel K, Schemann M, Needleman B, Harzman A, Christofi FL. Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X1, P2X2, P2X3 channels, P2Y and A3 metabotropic receptors in neurotransmission. Neuropharmacology. 95: 83-99. PMID 25724083 DOI: 10.1016/J.Neuropharm.2015.02.014  0.398
2015 Lampe SEG, Cowley C, Fitzgerald J, Mueller C, Christofi FL, Foust K. 617 Efficient Gene Delivery to the Enteric Nervous System by IV Delivery of AAV Vectors Gastroenterology. 148: S-121. DOI: 10.1016/S0016-5085(15)30420-0  0.303
2014 Ochoa-Cortes F, Liñán-Rico A, Jacobson KA, Christofi FL. Potential for developing purinergic drugs for gastrointestinal diseases. Inflammatory Bowel Diseases. 20: 1259-87. PMID 24859298 DOI: 10.1097/Mib.0000000000000047  0.322
2013 Liñán-Rico A, Wunderlich JE, Grants IS, Frankel WL, Xue J, Williams KC, Harzman AE, Enneking JT, Cooke HJ, Christofi FL. Purinergic autocrine regulation of mechanosensitivity and serotonin release in a human EC model: ATP-gated P2X3 channels in EC are downregulated in ulcerative colitis. Inflammatory Bowel Diseases. 19: 2366-79. PMID 23917247 DOI: 10.1097/Mib.0B013E31829Ecf4D  0.35
2013 Rico AL, Grants I, Wunderlich JE, Enneking J, Christofi FL. Sa2057 CA2+ Waves Are Mediated by a Uridine Nucleotide Receptor in a Human Enterochromaffin (BON) Cell Model - A Potential Regulatory Mechanism Involved in 5-HT Release Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)61366-9  0.342
2012 Wunderlich JE, Grants I, Needleman B, Otey AJ, Lopez E, Harzman A, Williams KC, Christofi FL. 183 Glial Transmission in Human Enteric Nervous System Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60172-3  0.314
2012 Wunderlich JE, Gisser JM, Gariepy CE, Grants I, Williams KC, Christofi FL. 182 Neural Circuit Behavior in Enteric Neural Plexus Developed From Neural Crest-Derived Stem Cells (ENPCs) Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60171-1  0.317
2011 Ren T, Grants I, Alhaj M, McKiernan M, Jacobson M, Hassanain HH, Frankel W, Wunderlich J, Christofi FL. Impact of disrupting adenosine A₃ receptors (A₃⁻/⁻ AR) on colonic motility or progression of colitis in the mouse. Inflammatory Bowel Diseases. 17: 1698-713. PMID 21744424 DOI: 10.1002/Ibd.21553  0.335
2011 Ren T, Grants I, Wunderlich JE, Cooke HJ, Frankel WL, Christofi FL. Ulcerative Colitis Alters Gut Expression of Purinergic Ionotropic P2X3 and Metabotropic a2B or a3 Receptors – Is P2X a Fast Mechanosensor in EC Cells? Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63481-1  0.351
2010 Ren T, Grants I, Rozmiarek AJ, McKiernan MP, Alhaj M, Hassanain HH, Griffin O, Jacobson M, Frankel WL, Christofi FL. S1732 Functional Knock-out of Adenosine a3 Receptors (a3−/−Ar) Alters Intestinal Motility and Protects Mice From Developing DSS – Colitis Gastroenterology. 138: S-262-S-263. DOI: 10.1016/S0016-5085(10)61202-4  0.319
2009 Bozarov A, Wang YZ, Yu JG, Wunderlich J, Hassanain HH, Alhaj M, Cooke HJ, Grants I, Ren T, Christofi FL. Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G1147-62. PMID 19808660 DOI: 10.1152/Ajpgi.00295.2009  0.331
2009 Germano PM, Lieu SN, Xue J, Cooke HJ, Christofi FL, Lu Y, Pisegna JR. PACAP induces signaling and stimulation of 5-hydroxytryptamine release and growth in neuroendocrine tumor cells. Journal of Molecular Neuroscience : Mn. 39: 391-401. PMID 19701709 DOI: 10.1007/S12031-009-9283-7  0.342
2009 Ren T, Wunderlich JE, Needleman B, Grants I, Javed AH, Christofi FL. S1792 Cyclic AMP Signaling in the Human Enteric Nervous System: Visualization of Dogiel Type II and Spiny Dogiel Type I Neurons in Response to Forskolin or Adenosine A2 Agonist Activation Using An Acrolein-Derivatized cAMP Antiserum Gastroenterology. 136: A-271. DOI: 10.1016/S0016-5085(09)61235-X  0.34
2009 Wunderlich JE, Ren T, Needleman B, Mikami DJ, Grants I, Christofi FL. 27 Novel Purinergic P1, P2X and P2Y Receptor Signaling Targets in the Human Enteric Nervous System and Glia Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60018-4  0.338
2008 Christofi FL. Purinergic receptors and gastrointestinal secretomotor function Purinergic Signalling. 4: 213-236. PMID 18604596 DOI: 10.1007/S11302-008-9104-4  0.4
2007 Chen Z, Suntres Z, Palmer J, Guzman J, Javed A, Xue J, Yu JG, Cooke H, Awad H, Hassanain HH, Cardounel AJ, Christofi FL. Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation. International Journal For Parasitology. 37: 743-61. PMID 17307183 DOI: 10.1016/J.Ijpara.2006.12.018  0.378
2004 Christofi FL, Kim M, Wunderlich JE, Xue J, Suntres Z, Cardounel A, Javed NH, Yu JG, Grants I, Cooke HJ. Endogenous adenosine differentially modulates 5-hydroxytryptamine release from a human enterochromaffin cell model. Gastroenterology. 127: 188-202. PMID 15236185 DOI: 10.1053/J.Gastro.2004.04.070  0.356
2004 Christofi FL, Wunderlich J, Yu JG, Wang YZ, Xue J, Guzman J, Javed N, Cooke H. Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors. The Journal of Comparative Neurology. 469: 16-36. PMID 14689471 DOI: 10.1002/Cne.10961  0.334
2004 Cooke HJ, Xue J, Yu JG, Wunderlich J, Wang YZ, Guzman J, Javed N, Christofi FL. Mechanical stimulation releases nucleotides that activate P2Y1 receptors to trigger neural reflex chloride secretion in guinea pig distal colon. The Journal of Comparative Neurology. 469: 1-15. PMID 14689470 DOI: 10.1002/Cne.10960  0.334
2003 Cooke HJ, Wang YZ, Wray D, O'Dorisio MS, Woltering EA, Coy DH, Murphy WA, Christofi FL, Gosh P, O'Dorisio TM. A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon. Regulatory Peptides. 114: 51-60. PMID 12763640 DOI: 10.1016/S0167-0115(03)00108-3  0.324
2003 Cooke HJ, Wunderlich J, Christofi FL. "The force be with you": ATP in gut mechanosensory transduction. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 18: 43-9. PMID 12644618 DOI: 10.1152/Nips.01411.2002  0.361
2003 Cooke HJ, Wang Y, Wray D, O'Dorisio MS, Woltering EA, Coy DH, Murphy WA, Christofi FL, Gosh P, O'Dorisio TM. Corrigendum to “A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon” [Regul. Pept. 114 (2003) 51–60] Regulatory Peptides. 115: 151. DOI: 10.1016/S0167-0115(03)00188-5  0.311
2003 Xue J, Wang Y, Jeon Y, Christofi FL, Cooke HJ. Nucleotide activation of P2Y receptors on submucosal neurons regulates chloride secretion via prostaglandin-dependent and independent mechanisms Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81725-0  0.365
2003 Xue J, Wunderlich JE, Christofi FL, Wang Y, Jeon Y, Cooke HJ. Over-expressed human BON cell P2Y11Rs in HEK-293 cells are coupled predominantly to a cAMP-dependent signaling pathway Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81722-5  0.319
2003 Wunderlich JE, Xue J, Cooke HJ, Christofi FL. Mechanical stimulation of human carcinoid BON cells leads to 5-HT release via a phospholipase C/Ca2+ signaling pathway Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81721-3  0.331
2003 Guzman J, Palmer J, Yu J, Suntres Z, Xue J, Cooke HJ, Wisel S, Michler RE, Hassanain H, Christofi FL. Amplification and immune modulation in the Ac/cAMP signaling pathway leads to hyperexcitability in intrinsic primary afferent (AH) neurons of Trichinella spiralis infected-guinea pigs* Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80143-9  0.319
2001 Kim M, Javed NH, Yu JG, Christofi F, Cooke HJ. Mechanical stimulation activates Gαq signaling pathways and 5-hydroxytryptamine release from human carcinoid BON cells Journal of Clinical Investigation. 108: 1051-1059. PMID 11581306 DOI: 10.1172/Jci12467  0.321
2001 Christofi FL. Unlocking mysteries of gut sensory transmission: is adenosine the key? Physiology. 16: 201-207. PMID 11572921 DOI: 10.1152/Physiologyonline.2001.16.5.201  0.347
2001 Yu J, Sharp SB, Guzman JE, Christofi FL. Adenosine A2b receptors exist at tachykinergic, cholinergic and VIP-ergic neural synapses in myenteric neurons of the rat intestine Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80875-X  0.344
2001 Sharp SB, Yu J, Guzman JE, Xue JJ, Cooke HJ, Christofi FL. Adenosine A3 receptor expression in peplidergic neural circuits of the rat distal colon Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80874-8  0.31
1998 Liu CY, Zhang H, Christofi FL. Adenylyl cyclase co-distribution with the CaBPs, calbindin-D28 and calretinin, varies with cell type: assessment with the fluorescent dye, BODIPY forskolin, in enteric ganglia. Cell and Tissue Research. 293: 57-73. PMID 9634598 DOI: 10.1007/S004410051098  0.307
1996 Christofi FL, Guan Z, Lucas JH, Rosenberg-Schaffer LJ, Stokes BT. Responsiveness to ATP with an increase in intracellular free Ca2+ is not a distinctive feature of calbindin-D28 immunoreactive neurons in myenteric ganglia Brain Research. 725: 241-246. PMID 8836530 DOI: 10.1016/0006-8993(96)00280-6  0.314
1993 Christofi FL, Wood JD. Effects of PACAP on morphologically identified myenteric neurons in guinea pig small bowel American Journal of Physiology - Gastrointestinal and Liver Physiology. 264. PMID 8096366 DOI: 10.1152/Ajpgi.1993.264.3.G414  0.36
1992 Christofi FL, Tack J, Wood JD. Suppression of nicotinic synaptic transmission by adenosine in myenteric ganglia of the guinea-pig gastric antrum. European Journal of Pharmacology. 216: 17-22. PMID 1326437 DOI: 10.1016/0014-2999(92)90203-G  0.328
1991 Christofi FL, Palmer JM, Wood JD. Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea-pig small intestine. European Journal of Pharmacology. 195: 333-9. PMID 1868879 DOI: 10.1016/0014-2999(91)90473-4  0.31
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