Year |
Citation |
Score |
2023 |
Mózner O, Zámbó B, Bartos Z, Gergely A, Szabó KS, Jezsó B, Telbisz Á, Várady G, Homolya L, Hegedűs T, Sarkadi B. Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop. Membranes. 13. PMID 37887994 DOI: 10.3390/membranes13100822 |
0.415 |
|
2023 |
Bakos É, Temesszentandrási-Ambrus C, Özvegy-Laczka C, Gáborik Z, Sarkadi B, Telbisz Á. Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters. International Journal of Molecular Sciences. 24. PMID 37510996 DOI: 10.3390/ijms241411237 |
0.305 |
|
2022 |
Kulin A, Kucsma N, Bohár B, Literáti-Nagy B, Korányi L, Cserepes J, Somogyi A, Sarkadi B, Szabó E, Várady G. Genetic Modulation of the GLUT1 Transporter Expression-Potential Relevance in Complex Diseases. Biology. 11. PMID 36421383 DOI: 10.3390/biology11111669 |
0.8 |
|
2022 |
Szabó E, Kulin A, Jezsó B, Kucsma N, Sarkadi B, Várady G. Selective Fluorescent Probes for High-Throughput Functional Diagnostics of the Human Multidrug Transporter P-Glycoprotein (ABCB1). International Journal of Molecular Sciences. 23. PMID 36142507 DOI: 10.3390/ijms231810599 |
0.384 |
|
2022 |
Mioč M, Telbisz Á, Radman K, Bertoša B, Šumanovac T, Sarkadi B, Kralj M. Interaction of crown ethers with the ABCG2 transporter and their implication for multidrug resistance reversal. Histochemistry and Cell Biology. PMID 35648291 DOI: 10.1007/s00418-022-02106-z |
0.361 |
|
2021 |
Szabó E, Kulin A, Mózner O, Korányi L, Literáti-Nagy B, Vitai M, Cserepes J, Sarkadi B, Várady G. Potential role of the ABCG2-Q141K polymorphism in type 2 diabetes. Plos One. 16: e0260957. PMID 34855903 DOI: 10.1371/journal.pone.0260957 |
0.786 |
|
2021 |
Ambrus C, Bakos É, Sarkadi B, Özvegy-Laczka C, Telbisz Á. Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect pharmacokinetics. Scientific Reports. 11: 17810. PMID 34497279 DOI: 10.1038/s41598-021-97160-3 |
0.331 |
|
2021 |
Mózner O, Zámbó B, Sarkadi B. Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants. Membranes. 11. PMID 34436349 DOI: 10.3390/membranes11080586 |
0.319 |
|
2021 |
Szabó E, Kulin A, Korányi L, Literáti-Nagy B, Cserepes J, Somogyi A, Sarkadi B, Várady G. Alterations in erythrocyte membrane transporter expression levels in type 2 diabetic patients. Scientific Reports. 11: 2765. PMID 33531564 DOI: 10.1038/s41598-021-82417-8 |
0.803 |
|
2020 |
Sarkadi B, Homolya L, Hegedűs T. The ABCG2/BCRP transporter and its variants - from structure to pathology. Febs Letters. PMID 33015850 DOI: 10.1002/1873-3468.13947 |
0.381 |
|
2020 |
Nagy T, Tóth Á, Telbisz Á, Sarkadi B, Tordai H, Tordai A, Hegedűs T. The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations. Cellular and Molecular Life Sciences : Cmls. PMID 32979053 DOI: 10.1007/s00018-020-03651-3 |
0.33 |
|
2020 |
Sarkadi B, Meszaros K, Krencz I, Canu L, Krokker L, Zakarias S, Barna G, Sebestyen A, Papay J, Hujber Z, Butz H, Darvasi O, Igaz P, Doczi J, Luconi M, et al. Glutaminases as a Novel Target for SDHB-Associated Pheochromocytomas/Paragangliomas. Cancers. 12. PMID 32150977 DOI: 10.3390/Cancers12030599 |
0.406 |
|
2020 |
Kovacsics D, Brózik A, Tihanyi B, Matula Z, Borsy A, Mészáros N, Szabó E, Németh E, Fóthi Á, Zámbó B, Szüts D, Várady G, Orbán TI, Apáti Á, Sarkadi B. Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells. Biochemical Pharmacology. 113865. PMID 32142727 DOI: 10.1016/J.Bcp.2020.113865 |
0.441 |
|
2020 |
Tóth S, Szepesi Á, Tran-Nguyen VK, Sarkadi B, Német K, Falson P, Di Pietro A, Szakács G, Boumendjel A. Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance. Molecules (Basel, Switzerland). 25. PMID 32050702 DOI: 10.3390/Molecules25030764 |
0.367 |
|
2019 |
Mózner O, Bartos Z, Zámbó B, Homolya L, Hegedűs T, Sarkadi B. Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism. Cells. 8. PMID 31597297 DOI: 10.3390/Cells8101215 |
0.497 |
|
2019 |
Zámbó B, Mózner O, Bartos Z, Török G, Várady G, Telbisz Á, Homolya L, Orbán TI, Sarkadi B. Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter. Cellular and Molecular Life Sciences : Cmls. PMID 31254042 DOI: 10.1007/S00018-019-03186-2 |
0.507 |
|
2019 |
Kovacsics D, Mészáros N, Tihanyi B, Matula Z, Borsy A, Szabó E, Várady G, Orbán T, Apáti Á, Fóthi Á, Brózik A, Sarkadi B. Abstract 3027: Pharmacological regulation of the ABCG2 multidrug transporter in A549 non-small cell lung cancer cells Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3027 |
0.364 |
|
2018 |
Apáti Á, Varga N, Berecz T, Erdei Z, Homolya L, Sarkadi B. Application of human pluripotent stem cells and pluripotent stem cell-derived cellular models for assessing drug toxicity. Expert Opinion On Drug Metabolism & Toxicology. PMID 30526128 DOI: 10.1080/17425255.2019.1558207 |
0.346 |
|
2018 |
Temesszentandrási-Ambrus C, Tóth S, Verma R, Bánhegyi P, Szabadkai I, Baska F, Szántai-Kis C, Hartkoorn RC, Lingerfelt MA, Sarkadi B, Szakács G, Őrfi L, Nagaraja V, Ekins S, Telbisz Á. Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters. Plos One. 13: e0202749. PMID 30183750 DOI: 10.1371/Journal.Pone.0202749 |
0.393 |
|
2018 |
Zámbó B, Bartos Z, Mózner O, Szabó E, Várady G, Poór G, Pálinkás M, Andrikovics H, Hegedűs T, Homolya L, Sarkadi B. Clinically relevant mutations in the ABCG2 transporter uncovered by genetic analysis linked to erythrocyte membrane protein expression. Scientific Reports. 8: 7487. PMID 29749379 DOI: 10.1038/S41598-018-25695-Z |
0.473 |
|
2018 |
Erdei Z, Schamberger A, Török G, Szebényi K, Várady G, Orbán TI, Homolya L, Sarkadi B, Apáti Á. Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells. Plos One. 13: e0194925. PMID 29649238 DOI: 10.1371/Journal.Pone.0194925 |
0.425 |
|
2018 |
Vőfély G, Berecz T, Szabó E, Szebényi K, Hathy E, Orbán TI, Sarkadi B, Homolya L, Marchetto MC, Réthelyi JM, Apáti Á. Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein. Molecular and Cellular Neurosciences. PMID 29425968 DOI: 10.1016/J.Mcn.2018.02.003 |
0.318 |
|
2018 |
Szabó E, Türk D, Telbisz Á, Kucsma N, Horváth T, Szakács G, Homolya L, Sarkadi B, Várady G. A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions. Plos One. 13: e0190629. PMID 29342177 DOI: 10.1371/Journal.Pone.0190629 |
0.434 |
|
2017 |
Tordai H, Jakab K, Gyimesi G, András K, Brózik A, Sarkadi B, Hegedus T. ABCMdb reloaded: updates on mutations in ATP binding cassette proteins. Database : the Journal of Biological Databases and Curation. 2017. PMID 28365738 DOI: 10.1093/Database/Bax023 |
0.341 |
|
2017 |
Zámbó B, Várady G, Padányi R, Szabó E, Németh A, Langó T, Enyedi Á, Sarkadi B. Decreased calcium pump expression in human erythrocytes is connected to a minor haplotype in the ATP2B4 gene. Cell Calcium. PMID 28216081 DOI: 10.1016/J.Ceca.2017.02.001 |
0.437 |
|
2016 |
László L, Sarkadi B, Hegedűs T. Jump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug Transporter. Plos One. 11: e0164426. PMID 27741279 DOI: 10.1371/Journal.Pone.0164426 |
0.48 |
|
2016 |
Nerada Z, Hegyi Z, Szepesi Á, Tóth S, Hegedüs C, Várady G, Matula Z, Homolya L, Sarkadi B, Telbisz Á. Application of fluorescent dye substrates for functional characterization of ABC multidrug transporters at a single cell level. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 27602881 DOI: 10.1002/Cyto.A.22931 |
0.482 |
|
2016 |
Sándor S, Jordanidisz T, Schamberger A, Várady G, Erdei Z, Apáti Á, Sarkadi B, Orbán TI. Functional characterization of the ABCG2 5' non-coding exon variants: Stem cell specificity, translation efficiency and the influence of drug selection. Biochimica Et Biophysica Acta. PMID 27191194 DOI: 10.1016/J.Bbagrm.2016.05.007 |
0.429 |
|
2016 |
Apáti Á, Berecz T, Sarkadi B. Calcium signaling in human pluripotent stem cells. Cell Calcium. 59: 117-23. PMID 26922096 DOI: 10.1016/J.Ceca.2016.01.005 |
0.346 |
|
2016 |
Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, ... ... Sarkadi B, et al. Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nature Communications. 7: 10286. PMID 26743714 DOI: 10.1038/Ncomms10286 |
0.332 |
|
2016 |
Apáti Á, Szebényi K, Erdei Z, Várady G, Orbán TI, Sarkadi B. The importance of drug transporters in human pluripotent stem cells and in early tissue differentiation. Expert Opinion On Drug Metabolism & Toxicology. 12: 77-92. PMID 26592535 DOI: 10.1517/17425255.2016.1121382 |
0.472 |
|
2015 |
Várady G, Szabó E, Fehér Á, Németh A, Zámbó B, Pákáski M, Janka Z, Sarkadi B. Alterations of membrane protein expression in red blood cells of Alzheimer's disease patients. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 334-8. PMID 27239515 DOI: 10.1016/J.Dadm.2015.06.007 |
0.389 |
|
2015 |
Szebényi K, Füredi A, Kolacsek O, Pergel E, Bősze Z, Bender B, Vajdovich P, Tóvári J, Homolya L, Szakács G, Héja L, Enyedi Á, Sarkadi B, Apáti Á, Orbán TI. Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling. Scientific Reports. 5: 12645. PMID 26234466 DOI: 10.1038/Srep12645 |
0.31 |
|
2015 |
Hegedűs T, Chaubey PM, Várady G, Szabó E, Sarankó H, Hofstetter L, Roschitzki B, Stieger B, Sarkadi B. Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications. Database : the Journal of Biological Databases and Curation. 2015: bav056. PMID 26078478 DOI: 10.1093/Database/Bav056 |
0.396 |
|
2015 |
Erdélyi-Belle B, Török G, Apáti Á, Sarkadi B, Schaff Z, Kiss A, Homolya L. Expression of Tight Junction Components in Hepatocyte-Like Cells Differentiated from Human Embryonic Stem Cells. Pathology Oncology Research : Por. 21: 1059-70. PMID 25845432 DOI: 10.1007/S12253-015-9936-5 |
0.391 |
|
2015 |
Bacskai I, Mázló A, Kis-Tóth K, Szabó A, Panyi G, Sarkadi B, Apáti Á, Rajnavölgyi É. Mesenchymal Stromal Cell-Like Cells Set the Balance of Stimulatory and Inhibitory Signals in Monocyte-Derived Dendritic Cells. Stem Cells and Development. 24: 1805-16. PMID 25808140 DOI: 10.1089/Scd.2014.0509 |
0.345 |
|
2015 |
Tóth A, Brózik A, Szakács G, Sarkadi B, Hegedüs T. A novel mathematical model describing adaptive cellular drug metabolism and toxicity in the chemoimmune system. Plos One. 10: e0115533. PMID 25699998 DOI: 10.1371/Journal.Pone.0115533 |
0.363 |
|
2015 |
Hegedüs C, Telbisz Á, Hegedűs T, Sarkadi B, Özvegy-Laczka C. Lipid regulation of the ABCB1 and ABCG2 multidrug transporters. Advances in Cancer Research. 125: 97-137. PMID 25640268 DOI: 10.1016/Bs.Acr.2014.10.004 |
0.424 |
|
2015 |
Gál Z, Hegedüs C, Szakács G, Váradi A, Sarkadi B, Özvegy-Laczka C. Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter. Biochimica Et Biophysica Acta. 1848: 477-87. PMID 25445676 DOI: 10.1016/J.Bbamem.2014.11.006 |
0.444 |
|
2015 |
Szepesi Á, Matula Z, Szigeti A, Várady G, Szabó G, Uher F, Sarkadi B, Német K. ABCG2 is a selectable marker for enhanced multilineage differentiation potential in periodontal ligament stem cells. Stem Cells and Development. 24: 244-52. PMID 25101689 DOI: 10.1089/Scd.2014.0177 |
0.431 |
|
2015 |
Szebényi K, Péntek A, Erdei Z, Várady G, Orbán TI, Sarkadi B, Apáti Á. Efficient generation of human embryonic stem cell-derived cardiac progenitors based on tissue-specific enhanced green fluorescence protein expression. Tissue Engineering. Part C, Methods. 21: 35-45. PMID 24734786 DOI: 10.1089/Ten.Tec.2013.0646 |
0.337 |
|
2015 |
Pálinkás M, Rásonyi R, Kiss C, Juhász P, Donáth J, Mikó I, Szekeres L, Tordai A, Andrikovics H, Szabó E, Várady G, Sarkadi B, Poór G. A2.36 Genetic variability and gout Annals of the Rheumatic Diseases. 74: A30.2-A31. DOI: 10.1136/Annrheumdis-2015-207259.71 |
0.383 |
|
2014 |
Koszarska M, Kucsma N, Kiss K, Varady G, Gera M, Antalffy G, Andrikovics H, Tordai A, Studzian M, Strapagiel D, Pulaski L, Tani Y, Sarkadi B, Szakacs G. Screening the expression of ABCB6 in erythrocytes reveals an unexpectedly high frequency of Lan mutations in healthy individuals. Plos One. 9: e111590. PMID 25360778 DOI: 10.1371/Journal.Pone.0111590 |
0.366 |
|
2014 |
Erdei Z, Lőrincz R, Szebényi K, Péntek A, Varga N, Likó I, Várady G, Szakács G, Orbán TI, Sarkadi B, Apáti A. Expression pattern of the human ABC transporters in pluripotent embryonic stem cells and in their derivatives. Cytometry. Part B, Clinical Cytometry. 86: 299-310. PMID 24729538 DOI: 10.1002/Cyto.B.21168 |
0.472 |
|
2014 |
Telbisz Á, Hegedüs C, Váradi A, Sarkadi B, Özvegy-Laczka C. Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 575-85. PMID 24384916 DOI: 10.1124/Dmd.113.055731 |
0.46 |
|
2013 |
Gauthier C, Ozvegy-Laczka C, Szakacs G, Sarkadi B, Di Pietro A. ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity. Frontiers in Pharmacology. 4: 138. PMID 24312054 DOI: 10.3389/Fphar.2013.00138 |
0.519 |
|
2013 |
Winter E, Lecerf-Schmidt F, Gozzi G, Peres B, Lightbody M, Gauthier C, Ozvegy-Laczka C, Szakacs G, Sarkadi B, Creczynski-Pasa TB, Boumendjel A, Di Pietro A. Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2. Journal of Medicinal Chemistry. 56: 9849-60. PMID 24304387 DOI: 10.1021/Jm401649J |
0.353 |
|
2013 |
Várady G, Cserepes J, Németh A, Szabó E, Sarkadi B. Cell surface membrane proteins as personalized biomarkers: where we stand and where we are headed. Biomarkers in Medicine. 7: 803-19. PMID 24044572 DOI: 10.2217/Bmm.13.90 |
0.789 |
|
2013 |
Sarankó H, Tordai H, Telbisz Á, Özvegy-Laczka C, Erdős G, Sarkadi B, Hegedűs T. Effects of the gout-causing Q141K polymorphism and a CFTR ΔF508 mimicking mutation on the processing and stability of the ABCG2 protein. Biochemical and Biophysical Research Communications. 437: 140-5. PMID 23800412 DOI: 10.1016/j.bbrc.2013.06.054 |
0.346 |
|
2013 |
Pomozi V, Le Saux O, Brampton C, Apana A, Iliás A, Szeri F, Martin L, Monostory K, Paku S, Sarkadi B, Szakács G, Váradi A. ABCC6 is a basolateral plasma membrane protein. Circulation Research. 112: e148-51. PMID 23625951 DOI: 10.1161/Circresaha.111.300194 |
0.364 |
|
2013 |
Apáti A, Pászty K, Hegedus L, Kolacsek O, Orbán TI, Erdei Z, Szebényi K, Péntek A, Enyedi A, Sarkadi B. Characterization of calcium signals in human embryonic stem cells and in their differentiated offspring by a stably integrated calcium indicator protein Cellular Signalling. 25: 752-759. PMID 23305950 DOI: 10.1016/J.Cellsig.2012.12.024 |
0.354 |
|
2013 |
Grabundzija I, Wang J, Sebe A, Erdei Z, Kajdi R, Devaraj A, Steinemann D, Szuhai K, Stein U, Cantz T, Schambach A, Baum C, Izsvák Z, Sarkadi B, Ivics Z. Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells. Nucleic Acids Research. 41: 1829-47. PMID 23275558 DOI: 10.1093/Nar/Gks1305 |
0.369 |
|
2013 |
Telbisz Á, Özvegy-Laczka C, Hegedűs T, Váradi A, Sarkadi B. Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein. The Biochemical Journal. 450: 387-95. PMID 23205634 DOI: 10.1042/Bj20121485 |
0.463 |
|
2013 |
Erdei Z, Sarkadi B, Brózik A, Szebényi K, Várady G, Makó V, Péntek A, Orbán TI, Apáti Á. Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response. European Biophysics Journal : Ebj. 42: 169-79. PMID 22851001 DOI: 10.1007/S00249-012-0838-0 |
0.457 |
|
2012 |
Kasza I, Várady G, Andrikovics H, Koszarska M, Tordai A, Scheffer GL, Németh A, Szakács G, Sarkadi B. Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variations. Plos One. 7: e48423. PMID 23166586 DOI: 10.1371/Journal.Pone.0048423 |
0.794 |
|
2012 |
de Boussac H, Orbán TI, Várady G, Tihanyi B, Bacquet C, Brózik A, Váradi A, Sarkadi B, Arányi T. Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters. Biochemical and Biophysical Research Communications. 426: 172-6. PMID 22922104 DOI: 10.1016/J.Bbrc.2012.08.046 |
0.39 |
|
2012 |
Gyimesi G, Borsodi D, Sarankó H, Tordai H, Sarkadi B, Hegedűs T. ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application. Human Mutation. 33: 1547-56. PMID 22693078 DOI: 10.1002/Humu.22138 |
0.327 |
|
2012 |
Hegedüs C, Truta-Feles K, Antalffy G, Várady G, Német K, Ozvegy-Laczka C, Kéri G, Orfi L, Szakács G, Settleman J, Váradi A, Sarkadi B. Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance. Biochemical Pharmacology. 84: 260-7. PMID 22548830 DOI: 10.1016/J.Bcp.2012.04.010 |
0.419 |
|
2012 |
Hegedüs C, Truta-Feles K, Antalffy G, Brózik A, Kasza I, Német K, Orbán TI, Özvegy-Laczka C, Váradi A, Sarkadi B. PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter. Biochemical and Biophysical Research Communications. 420: 869-74. PMID 22449574 DOI: 10.1016/J.Bbrc.2012.03.090 |
0.772 |
|
2012 |
Telbisz Á, Hegedüs C, Özvegy-Laczka C, Goda K, Várady G, Takáts Z, Szabó E, Sorrentino BP, Váradi A, Sarkadi B. Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 45: 101-9. PMID 22115866 DOI: 10.1016/J.Ejps.2011.10.021 |
0.485 |
|
2012 |
Apáti Á, Pászty K, Erdei Z, Szebényi K, Homolya L, Sarkadi B. Calcium signaling in pluripotent stem cells. Molecular and Cellular Endocrinology. 353: 57-67. PMID 21945604 DOI: 10.1016/J.Mce.2011.08.038 |
0.314 |
|
2012 |
Sarkadi B, Schatten G. Stem cell course in the Middle East: science diplomacy and international collaborations during the Arab spring. Stem Cell Reviews. 8: 87-90. PMID 21647552 DOI: 10.1007/S12015-011-9277-Z |
0.306 |
|
2012 |
Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedűs T. Corrigendum to “ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions” [Biochim. Biophys. Acta 1808 (2011) 2954–2964] Biochimica Et Biophysica Acta (Bba) - Biomembranes. 1818: 1435. DOI: 10.1016/J.Bbamem.2012.01.004 |
0.384 |
|
2011 |
Szebényi K, Erdei Z, Péntek A, Sebe A, Orbán TI, Sarkadi B, Apáti Á. Human pluripotent stem cells in pharmacological and toxicological screening: new perspectives for personalized medicine. Personalized Medicine. 8: 347-364. PMID 29783530 DOI: 10.2217/Pme.11.19 |
0.338 |
|
2011 |
Fülöp K, Jiang Q, Wetering KV, Pomozi V, Szabó PT, Arányi T, Sarkadi B, Borst P, Uitto J, Váradi A. ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum. Biochemical and Biophysical Research Communications. 415: 468-71. PMID 22056557 DOI: 10.1016/J.Bbrc.2011.10.095 |
0.346 |
|
2011 |
Varga N, Veréb Z, Rajnavölgyi E, Német K, Uher F, Sarkadi B, Apáti A. Mesenchymal stem cell like (MSCl) cells generated from human embryonic stem cells support pluripotent cell growth. Biochemical and Biophysical Research Communications. 414: 474-80. PMID 21971558 DOI: 10.1016/J.Bbrc.2011.09.089 |
0.328 |
|
2011 |
Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedus T. ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions. Biochimica Et Biophysica Acta. 1808: 2954-64. PMID 21840296 DOI: 10.1016/J.Bbamem.2011.07.038 |
0.387 |
|
2011 |
Procházková J, Kubala L, Kotasová H, Gudernová I, Šrámková Z, Pekarová M, Sarkadi B, Pacherník J. ABC transporters affect the detection of intracellular oxidants by fluorescent probes. Free Radical Research. 45: 779-87. PMID 21568630 DOI: 10.3109/10715762.2011.579120 |
0.411 |
|
2011 |
Brózik A, Hegedüs C, Erdei Z, Hegedus T, Özvegy-Laczka C, Szakács G, Sarkadi B. Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance? Expert Opinion On Drug Metabolism & Toxicology. 7: 623-42. PMID 21410427 DOI: 10.1517/17425255.2011.562892 |
0.408 |
|
2011 |
Homolya L, Orbán TI, Csanády L, Sarkadi B. Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane. Biochimica Et Biophysica Acta. 1808: 154-63. PMID 20691148 DOI: 10.1016/J.Bbamem.2010.07.031 |
0.472 |
|
2010 |
Sarkadi B, Szakács G. Understanding transport through pharmacological barriers--are we there yet? Nature Reviews. Drug Discovery. 9: 897-8. PMID 21031004 DOI: 10.1038/Nrd3187-C1 |
0.386 |
|
2010 |
Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gagliardi M, McElligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, et al. The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance. The Journal of Pharmacology and Experimental Therapeutics. 335: 302-13. PMID 20699436 DOI: 10.1124/Jpet.110.170415 |
0.301 |
|
2010 |
Nathwani SM, Butler S, Fayne D, McGovern NN, Sarkadi B, Meegan MJ, Lloyd DG, Campiani G, Lawler M, Williams DC, Zisterer DM. Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells. Cancer Chemotherapy and Pharmacology. 66: 585-96. PMID 20020128 DOI: 10.1007/S00280-009-1200-9 |
0.429 |
|
2010 |
Sarkadi B, Orbán TI, Szakács G, Várady G, Schamberger A, Erdei Z, Szebényi K, Homolya L, Apáti A. Evaluation of ABCG2 expression in human embryonic stem cells: crossing the same river twice? Stem Cells (Dayton, Ohio). 28: 174-6. PMID 19924769 DOI: 10.1002/Stem.262 |
0.502 |
|
2009 |
Kasza I, Hegyi Z, Szabó K, Andrikovics H, Német K, Váradi A, Sarkadi B, Homolya L. Model system for the analysis of cell surface expression of human ABCA1. Bmc Cell Biology. 10: 93. PMID 20025763 DOI: 10.1186/1471-2121-10-93 |
0.775 |
|
2009 |
Hegedűs C, Özvegy‐Laczka C, Apáti Á, Magócsi M, Német K, Őrfi L, Kéri G, Katona M, Takáts Z, Váradi A, Szakács G, Sarkadi B. Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties British Journal of Pharmacology. 158: 1153-1164. PMID 19785662 DOI: 10.1111/J.1476-5381.2009.00383.X |
0.399 |
|
2009 |
Katona M, Kiss K, Angyal V, Kucsma N, Sarkadi B, Takáts Z, Szakács G. A mass spectrometry based functional assay for the quantitative assessment of ABC transporter activity. Rapid Communications in Mass Spectrometry : Rcm. 23: 3372-6. PMID 19780062 DOI: 10.1002/Rcm.4259 |
0.416 |
|
2009 |
Hou YX, Li CZ, Palaniyandi K, Magtibay PM, Homolya L, Sarkadi B, Chang XB. Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport. Biochemistry. 48: 9122-31. PMID 19691360 DOI: 10.1021/Bi900675V |
0.496 |
|
2009 |
Hegedus C, Ozvegy-Laczka C, Szakács G, Sarkadi B. Interaction of ABC multidrug transporters with anticancer protein kinase inhibitors: substrates and/or inhibitors? Current Cancer Drug Targets. 9: 252-72. PMID 19442047 DOI: 10.2174/156800909788166565 |
0.454 |
|
2009 |
Orbán TI, Apáti A, Németh A, Varga N, Krizsik V, Schamberger A, Szebényi K, Erdei Z, Várady G, Karászi E, Homolya L, Német K, Gócza E, Miskey C, Mátés L, ... ... Sarkadi B, et al. Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery. Stem Cells (Dayton, Ohio). 27: 1077-87. PMID 19415778 DOI: 10.1002/Stem.45 |
0.372 |
|
2009 |
Polgar O, Ediriwickrema LS, Robey RW, Sharma A, Hegde RS, Li Y, Xia D, Ward Y, Dean M, Ozvegy-Laczka C, Sarkadi B, Bates SE. Arginine 383 is a crucial residue in ABCG2 biogenesis. Biochimica Et Biophysica Acta. 1788: 1434-43. PMID 19406100 DOI: 10.1016/J.Bbamem.2009.04.016 |
0.401 |
|
2009 |
Hegedus C, Szakács G, Homolya L, Orbán TI, Telbisz A, Jani M, Sarkadi B. Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays. Advanced Drug Delivery Reviews. 61: 47-56. PMID 19135105 DOI: 10.1016/J.Addr.2008.09.007 |
0.451 |
|
2008 |
Apáti A, Orbán TI, Varga N, Németh A, Schamberger A, Krizsik V, Erdélyi-Belle B, Homolya L, Várady G, Padányi R, Karászi E, Kemna EW, Német K, Sarkadi B. High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells. Biochimica Et Biophysica Acta. 1778: 2700-9. PMID 18793608 DOI: 10.1016/J.Bbamem.2008.08.010 |
0.496 |
|
2008 |
Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B. Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter. The Journal of Biological Chemistry. 283: 26059-70. PMID 18644784 DOI: 10.1074/Jbc.M803230200 |
0.791 |
|
2008 |
Seres L, Cserepes J, Elkind NB, Törocsik D, Nagy L, Sarkadi B, Homolya L. Functional ABCG1 expression induces apoptosis in macrophages and other cell types. Biochimica Et Biophysica Acta. 1778: 2378-87. PMID 18619413 DOI: 10.1016/J.Bbamem.2008.06.010 |
0.797 |
|
2008 |
Orbán TI, Seres L, Ozvegy-Laczka C, Elkind NB, Sarkadi B, Homolya L. Combined localization and real-time functional studies using a GFP-tagged ABCG2 multidrug transporter. Biochemical and Biophysical Research Communications. 367: 667-73. PMID 18182157 DOI: 10.1016/J.Bbrc.2007.12.172 |
0.494 |
|
2007 |
Fuller MD, Thompson CH, Zhang ZR, Freeman CS, Schay E, Szakács G, Bakos E, Sarkadi B, McMaster D, French RJ, Pohl J, Kubanek J, McCarty NA. State-dependent inhibition of cystic fibrosis transmembrane conductance regulator chloride channels by a novel peptide toxin. The Journal of Biological Chemistry. 282: 37545-55. PMID 17951250 DOI: 10.1074/Jbc.M708079200 |
0.328 |
|
2007 |
Schwab R, Micsik T, Szokolóczi O, Schafer E, Tihanyi B, Tihanyi T, Kupcsulik P, Diófalvi K, Mersich T, Besznyak I, Zarand A, Mihalik R, Sarkadi B, Kéri G, Pap A, et al. Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors. Assay and Drug Development Technologies. 5: 541-50. PMID 17767422 DOI: 10.1089/Adt.2007.067 |
0.444 |
|
2007 |
Telbisz A, Müller M, Ozvegy-Laczka C, Homolya L, Szente L, Váradi A, Sarkadi B. Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter. Biochimica Et Biophysica Acta. 1768: 2698-713. PMID 17662239 DOI: 10.1016/J.Bbamem.2007.06.026 |
0.488 |
|
2006 |
Müller M, Klein I, Kopácsi S, Remaley AT, Rajnavölgyi E, Sarkadi B, Váradi A. Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity. Febs Letters. 580: 6139-44. PMID 17055487 DOI: 10.1016/J.Febslet.2006.10.012 |
0.492 |
|
2006 |
Sarkadi B, Homolya L, Szakács G, Váradi A. Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiological Reviews. 86: 1179-236. PMID 17015488 DOI: 10.1152/physrev.00037.2005 |
0.395 |
|
2006 |
Szatmari I, Vámosi G, Brazda P, Balint BL, Benko S, Széles L, Jeney V, Ozvegy-Laczka C, Szántó A, Barta E, Balla J, Sarkadi B, Nagy L. Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. The Journal of Biological Chemistry. 281: 23812-23. PMID 16785230 DOI: 10.1074/Jbc.M604890200 |
0.473 |
|
2006 |
Polgar O, Ozvegy-Laczka C, Robey RW, Morisaki K, Okada M, Tamaki A, Koblos G, Elkind NB, Ward Y, Dean M, Sarkadi B, Bates SE. Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization. Biochemistry. 45: 5251-60. PMID 16618113 DOI: 10.1021/Bi0521590 |
0.477 |
|
2006 |
Cervenak J, Andrikovics H, Ozvegy-Laczka C, Tordai A, Német K, Váradi A, Sarkadi B. The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology. Cancer Letters. 234: 62-72. PMID 16337740 DOI: 10.1016/J.Canlet.2005.01.061 |
0.52 |
|
2006 |
Tusnády GE, Sarkadi B, Simon I, Váradi A. Membrane topology of human ABC proteins. Febs Letters. 580: 1017-22. PMID 16337630 DOI: 10.1016/J.Febslet.2005.11.040 |
0.372 |
|
2005 |
Ozvegy-Laczka C, Cserepes J, Elkind NB, Sarkadi B. Tyrosine kinase inhibitor resistance in cancer: role of ABC multidrug transporters. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 8: 15-26. PMID 15939339 DOI: 10.1016/J.Drup.2005.02.002 |
0.81 |
|
2005 |
Morisaki K, Robey RW, Ozvegy-Laczka C, Honjo Y, Polgar O, Steadman K, Sarkadi B, Bates SE. Single nucleotide polymorphisms modify the transporter activity of ABCG2. Cancer Chemotherapy and Pharmacology. 56: 161-72. PMID 15838659 DOI: 10.1007/S00280-004-0931-X |
0.455 |
|
2005 |
Elkind NB, Szentpétery Z, Apáti A, Ozvegy-Laczka C, Várady G, Ujhelly O, Szabó K, Homolya L, Váradi A, Buday L, Kéri G, Német K, Sarkadi B. Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib). Cancer Research. 65: 1770-7. PMID 15753373 DOI: 10.1158/0008-5472.Can-04-3303 |
0.764 |
|
2005 |
Ozvegy-Laczka C, Köblös G, Sarkadi B, Váradi A. Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Biochimica Et Biophysica Acta. 1668: 53-63. PMID 15670731 DOI: 10.1016/J.Bbamem.2004.11.005 |
0.525 |
|
2005 |
Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of Biological Chemistry. 280: 4219-27. PMID 15557326 DOI: 10.1074/Jbc.M411338200 |
0.785 |
|
2005 |
Ujhelly O, Kucsma N, Cervenak J, Chen L, Grez M, Sarkadi B, Nemet K. 1045. Overexpression of an ABCG2 Multidrug Transporter Variant Does Not Effect Proliferation or Differentiation of Hematopoetic Stem Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.592 |
0.78 |
|
2004 |
Glavinas H, Krajcsi P, Cserepes J, Sarkadi B. The role of ABC transporters in drug resistance, metabolism and toxicity. Current Drug Delivery. 1: 27-42. PMID 16305368 |
0.813 |
|
2004 |
Szentpétery Z, Kern A, Liliom K, Sarkadi B, Váradi A, Bakos E. The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers. The Journal of Biological Chemistry. 279: 41670-8. PMID 15252017 DOI: 10.1074/Jbc.M406484200 |
0.424 |
|
2004 |
Cserepes J, Szentpétery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H, Klein I, Homolya L, Váradi A, Sarkadi B, Elkind NB. Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization. Biochemical and Biophysical Research Communications. 320: 860-7. PMID 15240127 DOI: 10.1016/J.Bbrc.2004.06.037 |
0.811 |
|
2004 |
Sarkadi B, Ozvegy-Laczka C, Német K, Váradi A. ABCG2 -- a transporter for all seasons. Febs Letters. 567: 116-20. PMID 15165903 DOI: 10.1016/j.febslet.2004.03.123 |
0.422 |
|
2004 |
Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Molecular Pharmacology. 65: 1485-95. PMID 15155841 DOI: 10.1124/Mol.65.6.1485 |
0.801 |
|
2004 |
Kern A, Szentpétery Z, Liliom K, Bakos E, Sarkadi B, Váradi A. Nucleotides and transported substrates modulate different steps of the ATPase catalytic cycle of MRP1 multidrug transporter. The Biochemical Journal. 380: 549-60. PMID 14759224 DOI: 10.1042/Bj20031607 |
0.428 |
|
2004 |
Chu XY, Huskey SE, Braun MP, Sarkadi B, Evans DC, Evers R. Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3. The Journal of Pharmacology and Experimental Therapeutics. 309: 156-64. PMID 14722317 DOI: 10.1124/jpet.103.062091 |
0.324 |
|
2004 |
Ujhelly O, Cervenak J, Ozvegy CL, Grez M, Sarkadi B, Nemet K. 908. Selective enrichment of transduced cells for gene therapy of an inherited immune deficiency, chronic granulomatous disease Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.814 |
0.766 |
|
2003 |
Sinkó E, Iliás A, Ujhelly O, Homolya L, Scheffer GL, Bergen AA, Sarkadi B, Váradi A. Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells. Biochemical and Biophysical Research Communications. 308: 263-9. PMID 12901863 DOI: 10.1016/S0006-291X(03)01349-4 |
0.788 |
|
2003 |
Homolya L, Váradi A, Sarkadi B. Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate. Biofactors (Oxford, England). 17: 103-14. PMID 12897433 DOI: 10.1002/Biof.5520170111 |
0.489 |
|
2003 |
Bodo A, Bakos E, Szeri F, Varadi A, Sarkadi B. Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions. The Journal of Biological Chemistry. 278: 23529-37. PMID 12704183 DOI: 10.1074/Jbc.M303515200 |
0.471 |
|
2003 |
Bodó A, Bakos E, Szeri F, Váradi A, Sarkadi B. The role of multidrug transporters in drug availability, metabolism and toxicity. Toxicology Letters. 140: 133-43. PMID 12676459 |
0.397 |
|
2003 |
Ujhelly O, Ozvegy C, Várady G, Cervenak J, Homolya L, Grez M, Scheffer G, Roos D, Bates SE, Váradi A, Sarkadi B, Német K. Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells. Human Gene Therapy. 14: 403-12. PMID 12659681 DOI: 10.1089/104303403321209005 |
0.796 |
|
2003 |
Hegedüs T, Sessler T, Scott R, Thelin W, Bakos E, Váradi A, Szabó K, Homolya L, Milgram SL, Sarkadi B. C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins. Biochemical and Biophysical Research Communications. 302: 454-61. PMID 12615054 DOI: 10.1016/S0006-291X(03)00196-7 |
0.371 |
|
2002 |
Ozvegy C, Váradi A, Sarkadi B. Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation. The Journal of Biological Chemistry. 277: 47980-90. PMID 12374800 DOI: 10.1074/Jbc.M207857200 |
0.528 |
|
2002 |
Hegedus T, Orfi L, Seprodi A, Váradi A, Sarkadi B, Kéri G. Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1. Biochimica Et Biophysica Acta. 1587: 318-25. PMID 12084474 DOI: 10.1016/S0925-4439(02)00095-9 |
0.511 |
|
2002 |
Váradi A, Szakács G, Bakos E, Sarkadi B. P glycoprotein and the mechanism of multidrug resistance. Novartis Foundation Symposium. 243: 54-65; discussion 65. PMID 11990782 DOI: 10.1002/0470846356.Ch5 |
0.405 |
|
2002 |
Iliás A, Urbán Z, Seidl TL, Le Saux O, Sinkó E, Boyd CD, Sarkadi B, Váradi A. Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). The Journal of Biological Chemistry. 277: 16860-7. PMID 11880368 DOI: 10.1074/Jbc.M110918200 |
0.49 |
|
2001 |
Szakács G, Langmann T, Özvegy C, Orsó E, Schmitz G, Váradi A, Sarkadi B. Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter. Biochemical and Biophysical Research Communications. 288: 1258-1264. PMID 11700048 DOI: 10.1006/Bbrc.2001.5905 |
0.47 |
|
2001 |
Szakács G, Özvegy C, Bakos É, Sarkadi B, Váradi A. Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis. Biochemical Journal. 356: 71-75. PMID 11336637 DOI: 10.1042/0264-6021:3560071 |
0.455 |
|
2000 |
Szakács G, Özvegy C, Bakos É, Sarkadi B, Váradi A. Transition-state formation in ATPase-negative mutants of human MDR1 protein. Biochemical and Biophysical Research Communications. 276: 1314-1319. PMID 11027628 DOI: 10.1006/Bbrc.2000.3576 |
0.311 |
|
2000 |
Kern A, Felföldi F, Sarkadi B, Váradi A. Expression and Characterization of the N- and C-Terminal ATP-Binding Domains of MRP1☆ Biochemical and Biophysical Research Communications. 273: 913-919. PMID 10891347 DOI: 10.1006/Bbrc.2000.3040 |
0.35 |
|
1999 |
Sharom FJ, Yu X, Lu P, Liu R, Chu JW, Szabó K, Müller M, Hose CD, Monks A, Váradi A, Seprôdi J, Sarkadi B. Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells. Biochemical Pharmacology. 58: 571-86. PMID 10413294 DOI: 10.1016/S0006-2952(99)00139-2 |
0.458 |
|
1999 |
Szabó K, Szakács G, Hegedűs T, Sarkadi B. Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains. Journal of Biological Chemistry. 274: 12209-12212. PMID 10212185 DOI: 10.1074/Jbc.274.18.12209 |
0.401 |
|
1998 |
Váradi A, Tusnády GE, Bakos É, Sarkadi B. Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs Cytotechnology. 27: 71-79. PMID 19002784 DOI: 10.1023/A:1008031914247 |
0.42 |
|
1998 |
SzakÁCs G, Jakab K, Antal F, Sarkadi B. Diagnostics of multidrug resistance in cancer. Pathology & Oncology Research. 4: 251-257. PMID 9887354 DOI: 10.1007/Bf02905214 |
0.356 |
|
1997 |
Sarkadi B, Müller M. Search for specific inhibitors of multidrug resistance in cancer. Seminars in Cancer Biology. 8: 171-182. PMID 9465371 DOI: 10.1006/Scbi.1997.0069 |
0.403 |
|
1997 |
Szabó K, Bakos E, Welker E, Müller M, Goodfellow HR, Higgins CF, Váradi A, Sarkadi B. Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity. The Journal of Biological Chemistry. 272: 23165-71. PMID 9287320 DOI: 10.1074/Jbc.272.37.23165 |
0.408 |
|
1997 |
Bakos E, Klein I, Welker E, Szabó K, Müller M, Sarkadi B, Váradi A. Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region. The Biochemical Journal. 323: 777-83. PMID 9169612 DOI: 10.1042/Bj3230777 |
0.468 |
|
1996 |
Sarkadi B, Müller M, Holló Z. The multidrug transporters - Proteins of an ancient immune system Immunology Letters. 54: 215-219. PMID 9052881 DOI: 10.1016/S0165-2478(96)02676-4 |
0.477 |
|
1996 |
Bakos E, Hegedüs T, Holló Z, Welker E, Tusnády GE, Zaman GJ, Flens MJ, Váradi A, Sarkadi B. Membrane topology and glycosylation of the human multidrug resistance-associated protein. The Journal of Biological Chemistry. 271: 12322-6. PMID 8647833 DOI: 10.1074/Jbc.271.21.12322 |
0.477 |
|
1996 |
Holló Z, Homolya L, Hegedüs T, Sarkadi B. Transport properties of the multidrug resistance‐associated protein (MRP) in human tumour cells Febs Letters. 383: 99-104. PMID 8612802 DOI: 10.1016/0014-5793(96)00237-2 |
0.466 |
|
1996 |
Müller M, Bakos E, Welker E, Váradi A, Germann UA, Gottesman MM, Morse BS, Roninson IB, Sarkadi B. Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein. The Journal of Biological Chemistry. 271: 1877-83. PMID 8567633 DOI: 10.1074/Jbc.271.4.1877 |
0.459 |
|
1994 |
Sarkadi B, Müller M, Homolya L, Holló Z, Seprödi J, Germann UA, Gottesman MM, Price EM, Boucher RC. Interaction of bioactive hydrophobic peptides with the human multidrug transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 8: 766-70. PMID 7914178 DOI: 10.1096/Fasebj.8.10.7914178 |
0.437 |
|
1992 |
Papp B, Enyedi A, Pászty K, Kovács T, Sarkadi B, Gárdos G, Magnier C, Wuytack F, Enouf J. Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone. Biochemical Journal. 288: 297-302. PMID 1332697 DOI: 10.1042/Bj2880297 |
0.334 |
|
1990 |
Sarkadi B, Tordai A, Gárdos G. Membrane depolarization selectively inhibits receptor-operated calcium channels in human T (Jurkat) lymphoblasts. Biochimica Et Biophysica Acta. 1027: 130-140. PMID 2168754 DOI: 10.1016/0005-2736(90)90076-Z |
0.307 |
|
1990 |
Sarkadi B, Tordai A, Müller M, Gárdos G. Regulation of stimulus-induced calcium transport pathways in human T (Jurkat) lymphoblasts Molecular Immunology. 27: 1297-1306. PMID 1703278 DOI: 10.1016/0161-5890(90)90034-W |
0.301 |
|
1988 |
Sarkadi B, Enyedi A, Penniston JT, Verma AK, Dux L, Molnár E, Gárdos G. Characterization of membrane calcium pumps by simultaneous immunoblotting and 32P radiography. Biochimica Et Biophysica Acta. 939: 40-6. PMID 2964872 DOI: 10.1016/0005-2736(88)90044-2 |
0.317 |
|
1987 |
Sarkadi B, Enyedi Á, Gárdos G. Conformational changes of the in situ red cell membrane calcium pump affect its proteolysis Biochimica Et Biophysica Acta. 899: 129-133. PMID 2952170 DOI: 10.1016/0005-2736(87)90247-1 |
0.306 |
|
1984 |
Sarkadi B, Attisano L, Grinstein S, Buchwald M, Rothstein A. Volume regulation of Chinese hamster ovary cells in anisoosmotic media. Biochimica Et Biophysica Acta. 774: 159-68. PMID 6743652 DOI: 10.1016/0005-2736(84)90287-6 |
0.421 |
|
1984 |
Farkas G, Enyedi A, Sarkadi B, Gárdos G, Nagy Z, Faragó A. Cyclic AMP-dependent protein kinase stimulates the phosphorylation of phosphatidylinositol to phosphatidylinositol-4-monophosphate in a plasma membrane preparation from pig granulocytes. Biochemical and Biophysical Research Communications. 124: 871-6. PMID 6095827 DOI: 10.1016/0006-291X(84)91038-6 |
0.343 |
|
1984 |
Enyedi A, Faragó A, Sarkadi B, Gárdos G. Cyclic AMP-dependent protein kinase and Ca2+-calmodulin stimulate the formation of polyphosphoinositides in a sarcoplasmic reticulum preparation of rabbit heart. Febs Letters. 176: 235-8. PMID 6092135 DOI: 10.1016/0014-5793(84)80948-5 |
0.337 |
|
1983 |
Enyedi A, Faragó A, Sarkadi B, Szász I, Gárdos G. Cyclic AMP-dependent protein kinase stimulates the formation of polyphosphoinositides in the plasma membranes of different blood cells. Febs Letters. 161: 158-62. PMID 6309575 DOI: 10.1016/0014-5793(83)80751-0 |
0.393 |
|
1983 |
Sarkadi B, Enyedi A, Faragó A, Mészáros G, Kremmer T, Gárdos G. Cyclic AMP-dependent protein kinase stimulates the formation of polyphosphoinositides in lymphocyte plasma membrane. Febs Letters. 152: 195-8. PMID 6297997 DOI: 10.1016/0014-5793(83)80378-0 |
0.348 |
|
1982 |
Enyedi Á, Sarkadi B, Gárdos G. On the substrate specificity of the red cell calcium pump Biochimica Et Biophysica Acta. 687: 109-112. PMID 6978736 DOI: 10.1016/0005-2736(82)90177-8 |
0.365 |
|
1982 |
Enyedi Á, Sarkadi B, Nyers Á, Gárdos G. Effects of divalent metal ions on the calcium pump and membrane phosphorylation in human red cells Biochimica Et Biophysica Acta. 690: 41-49. PMID 6812632 DOI: 10.1016/0005-2736(82)90236-X |
0.384 |
|
1982 |
Sarkadi B, Enyedi Á, Szász I, Gárdos G. Active calcium transport and calcium-dependent membrane phosphorylation in human peripheral blood lymphocytes. Cell Calcium. 3: 163-182. PMID 6288251 DOI: 10.1016/0143-4160(82)90012-4 |
0.32 |
|
1982 |
Sarkadi B, Enyedi Á, Nyers Á, Gárdos G. The function and regulation of the calcium pump in the erythrocyte membrane. Annals of the New York Academy of Sciences. 402: 329-348. PMID 6220640 DOI: 10.1111/J.1749-6632.1982.Tb25753.X |
0.316 |
|
1981 |
Sarkadi B, Enyedi Á, Gárdos G. Metal-ATP complexes as substrates and free metal ions as activators of the red cell calcium pump Cell Calcium. 2: 449-458. DOI: 10.1016/0143-4160(81)90004-X |
0.322 |
|
1980 |
Sarkadi B, Szász I, Gárdos G. Characteristics and regulation of active calcium transport in inside-out red cell membrane vesicles. Biochimica Et Biophysica Acta. 598: 326-338. PMID 6769484 DOI: 10.1016/0005-2736(80)90010-3 |
0.407 |
|
1980 |
Enyedi Á, Sarkadi B, Szász I, Bot G, Gárdos G. Molecular properties of the red cell calcium pump: II. Effects of calmodulin, proteolytic digestion and drugs on the calcium-induced membrane phosphorylation by ATP in inside-out red cell membrane vesicles Cell Calcium. 1: 299-310. DOI: 10.1016/0143-4160(80)90032-9 |
0.372 |
|
1980 |
Sarkadi B, Enyedi A, Gárdos G. Molecular properties of the red cell calcium pump: I. Effects of calmodulin, proteolytic digestion and drugs on the kinetics of active calcium uptake in inside-out red cell membrane vesicles Cell Calcium. 1: 287-297. DOI: 10.1016/0143-4160(80)90031-7 |
0.357 |
|
1978 |
Szász I, Hasitz M, Sarkadi B, Gárdos G. Phosphorylation of the Ca2+ pump intermediate in intact red cells, isolated membranes and inside-out vesicles. Molecular and Cellular Biochemistry. 22: 147-152. PMID 745597 DOI: 10.1007/Bf00496240 |
0.347 |
|
1978 |
Szász I, Sarkadi B, Schubert A, Gárdos G. Effects of lanthanum on calcium-dependent phenomena in human red cells. Biochimica Et Biophysica Acta. 512: 331-340. PMID 152127 DOI: 10.1016/0005-2736(78)90257-2 |
0.34 |
|
1977 |
Szász I, Sarkadi B, Gárdos G. Mechanism of Ca2+-dependent selective rapid K+-transport induced by propranolol in red cells. The Journal of Membrane Biology. 35: 75-93. PMID 886606 DOI: 10.1007/Bf01869941 |
0.322 |
|
1977 |
Sarkadi B, Szász I, Gerlóczy A, Gárdos G. Transport parameters and stoichiometry of active calcium ion extrusion in intact human red cells. Biochimica Et Biophysica Acta. 464: 93-107. PMID 137747 DOI: 10.1016/0005-2736(77)90373-X |
0.312 |
|
1976 |
Sarkadi B, Szász I, Gárdos G. The use of ionophores of rapid loading of human red cells with radioactive cations for cation-pump studies. The Journal of Membrane Biology. 26: 357-370. PMID 58995 DOI: 10.1007/Bf01868883 |
0.334 |
|
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