| Year |
Citation |
Score |
| 2019 |
Baek SJ, Eling T. Growth differentiation factor 15 (GDF15): A survival protein with therapeutic potential in metabolic diseases. Pharmacology & Therapeutics. PMID 30790643 DOI: 10.1016/J.Pharmthera.2019.02.008 |
0.309 |
|
| 2014 |
Chrysovergis K, Wang X, Kosak J, Lee SH, Kim JS, Foley JF, Travlos G, Singh S, Baek SJ, Eling TE. NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. International Journal of Obesity (2005). 38: 1555-64. PMID 24531647 DOI: 10.1038/Ijo.2014.27 |
0.311 |
|
| 2014 |
Liggett JL, Zhang X, Eling TE, Baek SJ. Anti-tumor activity of non-steroidal anti-inflammatory drugs: cyclooxygenase-independent targets. Cancer Letters. 346: 217-24. PMID 24486220 DOI: 10.1016/J.Canlet.2014.01.021 |
0.348 |
|
| 2013 |
Kim JM, Kosak JP, Kim JK, Kissling G, Germolec DR, Zeldin DC, Bradbury JA, Baek SJ, Eling TE. NAG-1/GDF15 transgenic mouse has less white adipose tissue and a reduced inflammatory response. Mediators of Inflammation. 2013: 641851. PMID 23737651 DOI: 10.1155/2013/641851 |
0.345 |
|
| 2013 |
Wang X, Baek SJ, Eling TE. The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer. Biochemical Pharmacology. 85: 597-606. PMID 23220538 DOI: 10.1016/J.Bcp.2012.11.025 |
0.416 |
|
| 2012 |
Shimizu S, Kadowaki M, Yoshioka H, Kambe A, Watanabe T, Kinyamu HK, Eling TE. Proteasome inhibitor MG132 induces NAG-1/GDF15 expression through the p38 MAPK pathway in glioblastoma cells. Biochemical and Biophysical Research Communications. 430: 1277-82. PMID 23261467 DOI: 10.1016/j.bbrc.2012.11.137 |
0.343 |
|
| 2012 |
Wang X, Baek SJ, Eling T. COX inhibitors directly alter gene expression: role in cancer prevention? Cancer Metastasis Reviews. 30: 641-57. PMID 22020924 DOI: 10.1007/s10555-011-9301-4 |
0.387 |
|
| 2012 |
Wang X, Chrysovergis K, Bienstock RJ, Shim M, Eling TE. The H6D variant of NAG-1/GDF15 inhibits prostate xenograft growth in vivo. The Prostate. 72: 677-89. PMID 21809352 DOI: 10.1002/pros.21471 |
0.303 |
|
| 2011 |
Whitlock NC, Bahn JH, Lee SH, Eling TE, Baek SJ. Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3. Cancer Prevention Research (Philadelphia, Pa.). 4: 116-27. PMID 21205742 DOI: 10.1158/1940-6207.CAPR-10-0218 |
0.373 |
|
| 2011 |
Wang X, Xu Z, Chrysovergis K, Bienstock R, Shim M, Bensen JT, Fontham E, Smith GJ, Mohler J, Taylor J, Eling TE. Abstract 5541: The dual effects of H6D polymorphism of NAG-1/GDF15 in prostate cancer carcinogenesis Cancer Research. 71: 5541-5541. DOI: 10.1158/1538-7445.Am2011-5541 |
0.345 |
|
| 2010 |
Shim M, Foley J, Anna C, Mishina Y, Eling TE. Abstract LB-338: Increased apoptosis and p53 expression in sclerotome of COX-2 transgenic embryo Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-338 |
0.395 |
|
| 2009 |
Kambe A, Yoshioka H, Kamitani H, Watanabe T, Baek SJ, Eling TE. The cyclooxygenase inhibitor sulindac sulfide inhibits EP4 expression and suppresses the growth of glioblastoma cells. Cancer Prevention Research (Philadelphia, Pa.). 2: 1088-99. PMID 19934343 DOI: 10.1158/1940-6207.CAPR-09-0140 |
0.368 |
|
| 2009 |
Iguchi G, Chrysovergis K, Lee SH, Baek SJ, Langenbach R, Eling TE. A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2. Cancer Letters. 282: 152-8. PMID 19375854 DOI: 10.1016/j.canlet.2009.03.006 |
0.32 |
|
| 2008 |
Yoshioka H, Kamitani H, Watanabe T, Eling TE. Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. The Journal of Biological Chemistry. 283: 33129-37. PMID 18801729 DOI: 10.1074/jbc.M805248200 |
0.341 |
|
| 2008 |
Sukhthankar M, Yamaguchi K, Lee SH, McEntee MF, Eling TE, Hara Y, Baek SJ. A Green Tea Component Suppresses Posttranslational Expression of Basic Fibroblast Growth Factor in Colorectal Cancer Gastroenterology. 134: 1972-1980. PMID 18549879 DOI: 10.1053/J.Gastro.2008.02.095 |
0.416 |
|
| 2008 |
Shim M, Eling TE. Vitamin E succinate induces NAG-1 expression in a p38 kinase-dependent mechanism. Molecular Cancer Therapeutics. 7: 961-71. PMID 18413810 DOI: 10.1158/1535-7163.MCT-07-0470 |
0.339 |
|
| 2006 |
Eling TE, Baek SJ, Shim M, Lee CH. NSAID activated gene (NAG-1), a modulator of tumorigenesis. Journal of Biochemistry and Molecular Biology. 39: 649-55. PMID 17129398 |
0.315 |
|
| 2006 |
Yamaguchi K, Lee SH, Eling TE, Baek SJ. A novel peroxisome proliferator-activated receptor gamma ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells. Molecular Cancer Therapeutics. 5: 1352-61. PMID 16731769 DOI: 10.1158/1535-7163.MCT-05-0528 |
0.335 |
|
| 2006 |
Okazaki R, Moon Y, Norimura T, Eling T. Ionizing radiation enhances the expression of the nonsteroidal anti-inflammatory drug-activated gene (NAG1) by increasing the expression of TP53 in human colon cancer cells. Radiation Research. 165: 125-30. PMID 16435911 |
0.309 |
|
| 2006 |
Baek SJ, Eling TE. Changes in gene expression contribute to cancer prevention by COX inhibitors Progress in Lipid Research. 45: 1-16. PMID 16337272 DOI: 10.1016/J.Plipres.2005.10.001 |
0.409 |
|
| 2005 |
Lee SH, Yamaguchi K, Kim JS, Eling TE, Safe S, Park Y, Baek SJ. Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis. 27: 972-81. PMID 16286461 DOI: 10.1093/Carcin/Bgi268 |
0.333 |
|
| 2005 |
Moon Y, Bottone FG, McEntee MF, Eling TE. Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1. Molecular Cancer Therapeutics. 4: 1551-8. PMID 16227405 DOI: 10.1158/1535-7163.Mct-05-0213 |
0.326 |
|
| 2005 |
Kim JS, Baek SJ, Bottone FG, Sali T, Eling TE. Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells. Molecular Cancer Research : McR. 3: 511-7. PMID 16179498 DOI: 10.1158/1541-7786.Mcr-05-0011 |
0.309 |
|
| 2005 |
Bottone FG, Moon Y, Alston-Mills B, Eling TE. Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene. The Journal of Pharmacology and Experimental Therapeutics. 315: 668-77. PMID 16079301 DOI: 10.1124/Jpet.105.089607 |
0.316 |
|
| 2005 |
Bottone FG, Moon Y, Kim JS, Alston-Mills B, Ishibashi M, Eling TE. The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3). Molecular Cancer Therapeutics. 4: 693-703. PMID 15897233 DOI: 10.1158/1535-7163.Mct-04-0337 |
0.377 |
|
| 2005 |
Kim JS, Baek SJ, Sali T, Eling TE. The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15. Molecular Cancer Therapeutics. 4: 487-93. PMID 15767558 DOI: 10.1158/1535-7163.MCT-04-0201 |
0.317 |
|
| 2005 |
Shim M, Eling TE. Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells. The Journal of Biological Chemistry. 280: 18636-42. PMID 15757899 DOI: 10.1074/Jbc.M414613200 |
0.433 |
|
| 2005 |
Lee SH, Kim JS, Yamaguchi K, Eling TE, Baek SJ. Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner. Biochemical and Biophysical Research Communications. 328: 63-9. PMID 15670751 DOI: 10.1016/J.BBRC.2004.12.138 |
0.343 |
|
| 2005 |
Ishibashi M, Bottone FG, Taniura S, Kamitani H, Watanabe T, Eling TE. The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells. Experimental Cell Research. 302: 244-52. PMID 15561105 DOI: 10.1016/J.Yexcr.2004.09.021 |
0.321 |
|
| 2005 |
Kim KS, Yoon JH, Kim JK, Baek SJ, Eling TE, Lee WJ, Ryu JH, Lee JG, Lee JH, Yoo JB. Cyclooxygenase inhibitors induce apoptosis in oral cavity cancer cells by increased expression of nonsteroidal anti-inflammatory drug-activated gene. Biochemical and Biophysical Research Communications. 325: 1298-303. PMID 15555568 DOI: 10.1016/J.BBRC.2004.10.176 |
0.33 |
|
| 2004 |
Baek SJ, Kim JS, Moore SM, Lee SH, Martinez J, Eling TE. Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein. Molecular Pharmacology. 67: 356-64. PMID 15509713 DOI: 10.1124/MOL.104.005108 |
0.347 |
|
| 2004 |
Yamaguchi K, Lee S, Eling TE, Baek SJ. Identification of Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1) as a Novel Downstream Target of Phosphatidylinositol 3-Kinase/AKT/GSK-3β Pathway Journal of Biological Chemistry. 279: 49617-49623. PMID 15377673 DOI: 10.1074/Jbc.M408796200 |
0.431 |
|
| 2004 |
Martinez JM, Baek SJ, Mays DM, Tithof PK, Eling TE, Walker NJ. EGR1 is a novel target for AhR agonists in human lung epithelial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 429-35. PMID 15342960 DOI: 10.1093/toxsci/kfh272 |
0.305 |
|
| 2004 |
Baek SJ, Kim JS, Jackson FR, Eling TE, McEntee MF, Lee SH. Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis. 25: 2425-32. PMID 15308587 DOI: 10.1093/carcin/bgh255 |
0.31 |
|
| 2004 |
Nixon JB, Kim KS, Lamb PW, Bottone FG, Eling TE. 15-Lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 70: 7-15. PMID 14643174 DOI: 10.1016/J.Plefa.2003.06.001 |
0.305 |
|
| 2004 |
Bottone FG, Martinez JM, Alston-Mills B, Eling TE. Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells. Carcinogenesis. 25: 349-57. PMID 14633654 DOI: 10.1093/Carcin/Bgh016 |
0.363 |
|
| 2003 |
Baek SJ, Kim JS, Nixon JB, DiAugustine RP, Eling TE. Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. The Journal of Biological Chemistry. 279: 6883-92. PMID 14662774 DOI: 10.1074/JBC.M305295200 |
0.362 |
|
| 2003 |
Wilson LC, Baek SJ, Call A, Eling TE. Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) is induced by genistein through the expression of P53 in colorectal cancer cells International Journal of Cancer. 105: 747-753. PMID 12767058 DOI: 10.1002/ijc.11173 |
0.311 |
|
| 2003 |
Bottone FG, Martinez JM, Collins JB, Afshari CA, Eling TE. Gene modulation by the cyclooxygenase inhibitor, sulindac sulfide, in human colorectal carcinoma cells: possible link to apoptosis. The Journal of Biological Chemistry. 278: 25790-801. PMID 12734198 DOI: 10.1074/jbc.M301002200 |
0.356 |
|
| 2003 |
Newman D, Sakaue M, Koo JS, Kim KS, Baek SJ, Eling T, Jetten AM. Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids. Molecular Pharmacology. 63: 557-64. PMID 12606762 DOI: 10.1124/MOL.63.3.557 |
0.349 |
|
| 2003 |
Baek SJ, Wilson LC, Hsi LC, Eling TE. Troglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) ligand, selectively induces the early growth response-1 gene independently of PPARγ: A novel mechanism for its anti-tumorigenic activity Journal of Biological Chemistry. 278: 5845-5853. PMID 12475986 DOI: 10.1074/Jbc.M208394200 |
0.414 |
|
| 2003 |
Kelavkar U, Glasgow W, Eling TE. The effect of 15-lipoxygenase-1 expression on cancer cells. Current Urology Reports. 3: 207-14. PMID 12084190 DOI: 10.1007/s11934-002-0066-8 |
0.313 |
|
| 2002 |
Kelavkar U, Cohen C, Eling T, Badr K. 15-lipoxygenase-1 overexpression in prostate adenocarcinoma. Advances in Experimental Medicine and Biology. 507: 133-145. PMID 12664577 DOI: 10.1007/978-1-4615-0193-0_22 |
0.362 |
|
| 2002 |
Hsi LC, Wilson LC, Eling TE. Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate: Alteration in peroxisome proliferator-activated receptor γ Journal of Biological Chemistry. 277: 40549-40556. PMID 12189136 DOI: 10.1074/Jbc.M203522200 |
0.364 |
|
| 2002 |
Baek SJ, Wilson LC, Lee CH, Eling TE. Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene. The Journal of Pharmacology and Experimental Therapeutics. 301: 1126-31. PMID 12023546 DOI: 10.1124/jpet.301.3.1126 |
0.375 |
|
| 2002 |
Bottone FG, Baek SJ, Nixon JB, Eling TE. Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells. The Journal of Nutrition. 132: 773-8. PMID 11925476 DOI: 10.1093/Jn/132.4.773 |
0.305 |
|
| 2002 |
Baek SJ, Wilson LC, Eling TE. Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53 Carcinogenesis. 23: 425-434. PMID 11895857 DOI: 10.1093/CARCIN/23.3.425 |
0.316 |
|
| 2002 |
Taniura S, Kamitani H, Watanabe T, Eling TE. Transcriptional Regulation of Cyclooxygenase-1 by Histone Deacetylase Inhibitors in Normal Human Astrocyte Cells Journal of Biological Chemistry. 277: 16823-16830. PMID 11877441 DOI: 10.1074/Jbc.M200527200 |
0.424 |
|
| 2002 |
Kawajiri H, Hsi LC, Kamitani H, Ikawa H, Geller M, Ward T, Eling TE, Glasgow WC. Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity. Archives of Biochemistry and Biophysics. 398: 51-60. PMID 11811948 DOI: 10.1006/Abbi.2001.2685 |
0.369 |
|
| 2001 |
Hsi LC, Wilson L, Nixon J, Eling TE. 15-Lipoxygenase-1 Metabolites Down-regulate Peroxisome Proliferator-activated Receptor γ via the MAPK Signaling Pathway Journal of Biological Chemistry. 276: 34545-34552. PMID 11447213 DOI: 10.1074/Jbc.M100280200 |
0.423 |
|
| 2001 |
Baek SJ, Horowitz JM, Eling TE. Molecular cloning and characterization of human nonsteroidal anti-inflammatory drug-activated gene promoter. Basal transcription is mediated by Sp1 and Sp3 Journal of Biological Chemistry. 276: 33384-33392. PMID 11445565 DOI: 10.1074/Jbc.M101814200 |
0.324 |
|
| 2001 |
Kamitani H, Taniura S, Ikawa H, Watanabe T, Kelavkar UP, Eling TE. Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma Carcinogenesis. 22: 187-191. PMID 11159758 DOI: 10.1093/Carcin/22.1.187 |
0.376 |
|
| 2000 |
Kelavkar UP, Cohen C, Kamitani H, Eling TE, Badr KF. Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging. Carcinogenesis. 21: 1777-1787. PMID 11023533 DOI: 10.1093/Carcin/21.10.1777 |
0.358 |
|
| 1999 |
Kamitani H, Geller M, Eling T. The possible involvement of 15-lipoxygenase/leukocyte type 12-lipoxygenase in colorectal carcinogenesis. Advances in Experimental Medicine and Biology. 469: 593-598. PMID 10667387 DOI: 10.1007/978-1-4615-4793-8_86 |
0.394 |
|
| 1999 |
Kamitani H, Ikawa H, Hsi LC, Watanabe T, DuBois RN, Eling TE. Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate. Archives of Biochemistry and Biophysics. 368: 45-55. PMID 10415110 DOI: 10.1006/Abbi.1999.1284 |
0.405 |
|
| 1998 |
Kamitani H, Geller M, Eling T. Expression of 15-Lipoxygenase by Human Colorectal Carcinoma Caco-2 Cells during Apoptosis and Cell Differentiation Journal of Biological Chemistry. 273: 21569-21577. PMID 9705287 DOI: 10.1074/Jbc.273.34.21569 |
0.435 |
|
| 1997 |
Glasgow WC, Hui R, Everhart AL, Jayawickreme SP, Angerman-Stewart J, Han B, Eling TE. The Linoleic Acid Metabolite, (13S)-Hydroperoxyoctadecadienoic Acid, Augments the Epidermal Growth Factor Receptor Signaling Pathway by Attenuation of Receptor Dephosphorylation DIFFERENTIAL RESPONSE IN SYRIAN HAMSTER EMBRYO TUMOR SUPPRESSOR PHENOTYPES Journal of Biological Chemistry. 272: 19269-19276. PMID 9235921 DOI: 10.1074/Jbc.272.31.19269 |
0.355 |
|
| 1997 |
Reddy N, Everhart A, Eling T, Glasgow W. Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. Biochemical and Biophysical Research Communications. 231: 111-116. PMID 9070230 DOI: 10.1006/Bbrc.1997.6048 |
0.383 |
|
| 1996 |
Curtis JF, Reddy NG, Mason RP, Kalyanaraman B, Eling TE. Nitric oxide: a prostaglandin H synthase 1 and 2 reducing cosubstrate that does not stimulate cyclooxygenase activity or prostaglandin H synthase expression in murine macrophages. Archives of Biochemistry and Biophysics. 335: 369-376. PMID 8914934 DOI: 10.1006/Abbi.1996.0518 |
0.302 |
|
| 1996 |
Rao GN, Glasgow WC, Eling TE, Runge MS. Role of Hydroperoxyeicosatetraenoic Acids in Oxidative Stress-induced Activating Protein 1 (AP-1) Activity Journal of Biological Chemistry. 271: 27760-27764. PMID 8910370 DOI: 10.1074/Jbc.271.44.27760 |
0.375 |
|
| 1996 |
Chulada PC, Loftin CD, Winn VD, Young DA, Tiano HF, Eling TE, Langenbach R. Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid. Archives of Biochemistry and Biophysics. 330: 301-13. PMID 8660660 DOI: 10.1006/Abbi.1996.0257 |
0.358 |
|
| 1989 |
Hughes MF, Chamulitrat W, Mason RP, Eling TE. Epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene via a hydroperoxide-dependent mechanism catalyzed by lipoxygenases Carcinogenesis. 10: 2075-2080. PMID 2553290 DOI: 10.1093/Carcin/10.11.2075 |
0.302 |
|
| 1987 |
Madden MC, Eling TE, Friedman M. Ozone inhibits endothelial cell cyclooxygenase activity through formation of hydrogen peroxide Prostaglandins. 34: 445-463. PMID 3124213 DOI: 10.1016/0090-6980(87)90089-X |
0.306 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2008 |
Zhu H, Glasgow W, George MD, Chrysovergis K, Olden K, Roberts JD, Eling T. 15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity. International Journal of Cancer. Journal International Du Cancer. 123: 2741-9. PMID 18785202 DOI: 10.1002/ijc.23855 |
0.294 |
|
| 2010 |
Shim M, Foley J, Anna C, Mishina Y, Eling T. Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton. The Journal of Biological Chemistry. 285: 16206-17. PMID 20236942 DOI: 10.1074/Jbc.M109.078576 |
0.294 |
|
| 2009 |
Cekanova M, Lee SH, Donnell RL, Sukhthankar M, Eling TE, Fischer SM, Baek SJ. Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice. Cancer Prevention Research (Philadelphia, Pa.). 2: 450-8. PMID 19401523 DOI: 10.1158/1940-6207.CAPR-09-0057 |
0.293 |
|
| 2002 |
Kim KS, Baek SJ, Flake GP, Loftin CD, Calvo BF, Eling TE. Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue. Gastroenterology. 122: 1388-98. PMID 11984525 |
0.292 |
|
| 2008 |
Kambe A, Iguchi G, Moon Y, Kamitani H, Watanabe T, Eling TE. Regulation of EP4 expression via the Sp-1 transcription factor: inhibition of expression by anti-cancer agents. Biochimica Et Biophysica Acta. 1783: 1211-9. PMID 18346464 DOI: 10.1016/j.bbamcr.2008.01.032 |
0.284 |
|
| 2002 |
Kamitani H, Taniura S, Watanabe K, Sakamoto M, Watanabe T, Eling T. Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. Neuro-Oncology. 4: 95-101. PMID 11916500 DOI: 10.1093/neuonc/4.2.95 |
0.283 |
|
| 2019 |
Martinez JM, Eling TE. Activation of TRPA1 by volatile organic chemicals leading to sensory irritation. Altex. PMID 31026039 DOI: 10.14573/Altex.1811012 |
0.276 |
|
| 2006 |
Baek SJ, Okazaki R, Lee SH, Martinez J, Kim JS, Yamaguchi K, Mishina Y, Martin DW, Shoieb A, Mcentee MF, Eling TE. Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1 Over Expression in Transgenic Mice Suppresses Intestinal Neoplasia Gastroenterology. 131: 1553-1560. PMID 17101328 DOI: 10.1053/J.Gastro.2006.09.015 |
0.273 |
|
| 2004 |
Jain AK, Moore SM, Yamaguchi K, Eling TE, Baek SJ. Selective nonsteroidal anti-inflammatory drugs induce thymosin beta-4 and alter actin cytoskeletal organization in human colorectal cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 311: 885-91. PMID 15292456 DOI: 10.1124/JPET.104.070664 |
0.272 |
|
| 2006 |
Lambert JR, Kelly JA, Shim M, Huffer WE, Nordeen SK, Baek SJ, Eling TE, Lucia MS. Prostate derived factor in human prostate cancer cells: gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth. Journal of Cellular Physiology. 208: 566-74. PMID 16741990 DOI: 10.1002/Jcp.20692 |
0.272 |
|
| 2011 |
Wang X, Kingsley PJ, Marnett LJ, Eling TE. The role of NAG-1/GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac. Cancer Prevention Research (Philadelphia, Pa.). 4: 150-60. PMID 21205743 DOI: 10.1158/1940-6207.Capr-10-0196 |
0.271 |
|
| 2007 |
Lee CR, Bottone FG, Krahn JM, Li L, Mohrenweiser HW, Cook ME, Petrovich RM, Bell DA, Eling TE, Zeldin DC. Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenetics and Genomics. 17: 145-60. PMID 17301694 DOI: 10.1097/01.Fpc.0000236340.87540.E3 |
0.265 |
|
| 2006 |
Martinez JM, Sali T, Okazaki R, Anna C, Hollingshead M, Hose C, Monks A, Walker NJ, Baek SJ, Eling TE. Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate-derived factor, a putative tumor suppressor, inhibits tumor growth. The Journal of Pharmacology and Experimental Therapeutics. 318: 899-906. PMID 16714403 DOI: 10.1124/jpet.105.100081 |
0.261 |
|
| 2022 |
Wang Y, Chen C, Chen J, Sang T, Peng H, Lin X, Zhao Q, Chen S, Eling T, Wang X. Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation. Redox Biology. 52: 102322. PMID 35504134 DOI: 10.1016/j.redox.2022.102322 |
0.256 |
|
| 2016 |
Binder AK, Kosak JP, Janardhan KS, Moser G, Eling TE, Korach KS. Correction: Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation. Plos One. 11: e0151504. PMID 26963910 DOI: 10.1371/journal.pone.0151504 |
0.254 |
|
| 2005 |
Malathi K, Paranjape JM, Bulanova E, Shim M, Guenther-Johnson JM, Faber PW, Eling TE, Williams BR, Silverman RH. A transcriptional signaling pathway in the IFN system mediated by 2'-5'-oligoadenylate activation of RNase L. Proceedings of the National Academy of Sciences of the United States of America. 102: 14533-8. PMID 16203993 DOI: 10.1073/pnas.0507551102 |
0.244 |
|
| 2008 |
Kang HJ, Kim HJ, Kwon SH, Kang BD, Eling TE, Lee SH, Bae I. BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity. Cancer Chemotherapy and Pharmacology. 62: 689-97. PMID 18074135 DOI: 10.1007/s00280-007-0657-7 |
0.241 |
|
| 2015 |
Wang X, Chrysovergis K, Kosak J, Kissling G, Streicker M, Moser G, Li R, Eling TE. hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling. Aging. 6: 690-704. PMID 25239873 DOI: 10.18632/aging.100687 |
0.239 |
|
| 2016 |
Binder AK, Kosak JP, Janardhan KS, Janhardhan KS, Moser G, Eling TE, Korach KS. Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation. Plos One. 11: e0146518. PMID 26745373 DOI: 10.1371/journal.pone.0146518 |
0.237 |
|
| 2005 |
House RL, Cassady JP, Eisen EJ, Eling TE, Collins JB, Grissom SF, Odle J. Functional genomic characterization of delipidation elicited by trans-10, cis-12-conjugated linoleic acid (t10c12-CLA) in a polygenic obese line of mice. Physiological Genomics. 21: 351-61. PMID 15888570 DOI: 10.1152/Physiolgenomics.00244.2004 |
0.235 |
|
| 2003 |
Amin R, Kamitani H, Sultana H, Taniura S, Islam A, Sho A, Ishibashi M, Eling TE, Watanabe T. Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells. Neurological Research. 25: 370-6. PMID 12870263 DOI: 10.1179/016164103101201706 |
0.234 |
|
| 2022 |
Wang Y, Chen J, Sang T, Chen C, Peng H, Lin X, Zhao Q, Chen S, Eling T, Wang X. NAG-1/GDF15 protects against streptozotocin-induced type 1 diabetes by inhibiting apoptosis, preserving beta-cell function, and suppressing inflammation in pancreatic islets. Molecular and Cellular Endocrinology. 549: 111643. PMID 35398052 DOI: 10.1016/j.mce.2022.111643 |
0.234 |
|
| 2010 |
Ashwell MS, Ceddia RP, House RL, Cassady JP, Eisen EJ, Eling TE, Collins JB, Grissom SF, Odle J. Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis. The Journal of Nutritional Biochemistry. 21: 848-55. PMID 19800780 DOI: 10.1016/J.Jnutbio.2009.06.013 |
0.234 |
|
| 2009 |
Taniura S, Kamitani H, Watanabe T, Eling TE. Induction of cyclooxygenase-2 expression by interleukin-1beta in human glioma cell line, U87MG. Neurologia Medico-Chirurgica. 48: 500-5; discussion 50. PMID 19029777 DOI: 10.2176/nmc.48.500 |
0.233 |
|
| 2014 |
Li R, Grimm SA, Chrysovergis K, Kosak J, Wang X, Du Y, Burkholder A, Janardhan K, Mav D, Shah R, Eling TE, Wade PA. Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression. Cell Metabolism. 19: 702-11. PMID 24703701 DOI: 10.1016/j.cmet.2014.03.012 |
0.221 |
|
| 2021 |
Lertpatipanpong P, Lee J, Kim I, Eling T, Oh SY, Seong JK, Baek SJ. The anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice. Scientific Reports. 11: 15027. PMID 34294853 DOI: 10.1038/s41598-021-94581-y |
0.216 |
|
| 2004 |
Wang T, Qin L, Liu B, Liu Y, Wilson B, Eling TE, Langenbach R, Taniura S, Hong JS. Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia. Journal of Neurochemistry. 88: 939-47. PMID 14756815 DOI: 10.1046/J.1471-4159.2003.02242.X |
0.213 |
|
| 2022 |
Chen J, Peng H, Chen C, Wang Y, Sang T, Cai Z, Zhao Q, Chen S, Lin X, Eling T, Wang X. NAG-1/GDF15 inhibits diabetic nephropathy via inhibiting AGE/RAGE-mediated inflammation signaling pathways in C57BL/6 mice and HK-2 cells. Life Sciences. 311: 121142. PMID 36367498 DOI: 10.1016/j.lfs.2022.121142 |
0.207 |
|
| 2012 |
Kadowaki M, Yoshioka H, Kamitani H, Watanabe T, Wade PA, Eling TE. DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines. International Journal of Cancer. Journal International Du Cancer. 130: 267-77. PMID 21437897 DOI: 10.1002/ijc.26082 |
0.204 |
|
| 2017 |
Wu Q, Jiang D, Schaefer NR, Harmacek L, O'Connor BP, Eling T, Eickelberg O, Chu HW. Over-production of growth differentiation factor 15 (GDF15) promotes human rhinovirus infection and virus-induced inflammation in the lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00324.2017. PMID 29192094 DOI: 10.1152/ajplung.00324.2017 |
0.199 |
|
| 2008 |
Moon Y, Kim JI, Yang H, Eling TE. Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways. Life Sciences. 82: 591-9. PMID 18261746 DOI: 10.1016/j.lfs.2007.11.030 |
0.172 |
|
| 2005 |
Moon Y, Glasgow WC, Eling TE. Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways. The Journal of Pharmacology and Experimental Therapeutics. 315: 788-95. PMID 16081677 DOI: 10.1124/jpet.105.084434 |
0.162 |
|
| 2003 |
Hsi LC, Angerman-Stewart J, Eling TE. Modulation of cyclooxygenase-2 expression by APC in HT-29 human colorectal carcinoma cells. Advances in Experimental Medicine and Biology. 507: 127-31. PMID 12664576 DOI: 10.1007/978-1-4615-0193-0_21 |
0.153 |
|
| 2013 |
Wang X, Chrysovergis K, Kosak J, Eling TE. Lower NLRP3 inflammasome activity in NAG-1 transgenic mice is linked to a resistance to obesity and increased insulin sensitivity. Obesity (Silver Spring, Md.). 22: 1256-63. PMID 24124102 DOI: 10.1002/oby.20638 |
0.146 |
|
| 2015 |
van 't Erve TJ, Lih FB, Kadiiska MB, Deterding LJ, Eling TE, Mason RP. Reinterpreting the best biomarker of oxidative stress: The 8-iso-PGF(2α)/PGF(2α) ratio distinguishes chemical from enzymatic lipid peroxidation. Free Radical Biology & Medicine. 83: 245-51. PMID 25772010 DOI: 10.1016/J.Freeradbiomed.2015.03.004 |
0.144 |
|
| 2003 |
Lee CH, Jang YS, Her SJ, Moon YM, Baek SJ, Eling T. Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-beta activity through the inhibition of Smad signaling pathway. Experimental Cell Research. 289: 335-41. PMID 14499634 DOI: 10.1016/S0014-4827(03)00282-9 |
0.143 |
|
| 2007 |
Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT, Moroney JW, Reed CH, Luban NL, Wang RH, Eling TE, Childs R, Ganz T, Leitman SF, Fucharoen S, et al. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nature Medicine. 13: 1096-101. PMID 17721544 DOI: 10.1038/Nm1629 |
0.127 |
|
| 2002 |
Glasgow WC, Hui R, Kameda H, Eling TE. 13(S)-HPODE modulates mitogenic signal transduction through enhancing the phosphorylation and association of EGF receptor with the tyrosine phosphatase SHP-2 Advances in Experimental Medicine and Biology. 507: 463-467. PMID 12664627 |
0.12 |
|
| 2016 |
Van't Erve TJ, Lih FB, Jelsema C, Deterding LJ, Eling TE, Mason RP, Kadiiska MB. Reinterpreting the best biomarker of oxidative stress: The 8-iso-prostaglandin F2α/prostaglandin F2α ratio shows complex origins of lipid peroxidation biomarkers in animal models. Free Radical Biology & Medicine. PMID 26964509 DOI: 10.1016/J.Freeradbiomed.2016.03.001 |
0.104 |
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