Year |
Citation |
Score |
2020 |
Bucur O, Stancu AL, Muraru MS, Melet A, Petrescu SM, Khosravi-Far R. PLK1 is a binding partner and a negative regulator of FOXO3 tumor suppressor. Discoveries (Craiova, Romania). 2. PMID 26280018 DOI: 10.15190/d.2014.8 |
0.306 |
|
2017 |
Esposti MD, Matarrese P, Tinari A, Longo A, Recalchi S, Khosravi-Far R, Malorni W, Misasi R, Garofalo T, Sorice M. Changes in membrane lipids drive increased endocytosis following Fas ligation. Apoptosis. 22: 681-695. PMID 28299505 DOI: 10.1007/S10495-017-1362-6 |
0.37 |
|
2015 |
Bucur O, Gaidos G, Yatawara A, Pennarun B, Rupasinghe C, Roux J, Andrei S, Guo B, Panaitiu A, Pellegrini M, Mierke DF, Khosravi-Far R. A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death. Scientific Reports. 5: 9893. PMID 25962125 DOI: 10.1038/Srep09893 |
0.432 |
|
2014 |
Gunda V, Bucur O, Varnau J, Borre PV, Bernasconi MJ, Khosravi-Far R, Parangi S. Blocks to thyroid cancer cell apoptosis can be overcome by inhibition of the MAPK and PI3K/AKT pathways. Cell Death and Disease. 5. PMID 24603332 DOI: 10.1038/Cddis.2014.78 |
0.482 |
|
2014 |
Sandra F, Khosravi-Far R. Ser81 Survivin Induced Protein Kinase A (PKA)-dependent Phosphatidylinositol 3-kinase (PI3K) Activity The Indonesian Biomedical Journal. 6: 157. DOI: 10.18585/Inabj.V6I3.28 |
0.384 |
|
2013 |
Pennarun B, Gaidos G, Bucur O, Tinari A, Rupasinghe C, Jin T, Dewar R, Song K, Santos MT, Malorni W, Mierke D, Khosravi-Far R. killerFLIP: a novel lytic peptide specifically inducing cancer cell death. Cell Death & Disease. 4: e894. PMID 24176852 DOI: 10.1038/Cddis.2013.401 |
0.41 |
|
2013 |
Bucur O, Stancu AL, Goganau I, Petrescu SM, Pennarun B, Bertomeu T, Dewar R, Khosravi-Far R. Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells. Plos One. 8: e77390. PMID 24155950 DOI: 10.1371/Journal.Pone.0077390 |
0.4 |
|
2013 |
Nadler M, Zabolian R, Ndebele K, bertomeu t, Bucur O, Pennarun B, Khosravi-Far R. Abstract 3058: miRNA networks mediate the tumor suppressive function of FOXO proteins. Cancer Research. 73: 3058-3058. DOI: 10.1158/1538-7445.Am2013-3058 |
0.326 |
|
2013 |
Gunda V, Bucur O, Varnau J, Lawler J, Khosravi-Far R, Parangi S. TRAIL Induced Apoptosis is Enhanced by Inhibition of the MAPK and PI3K/AKT Pathways in Thyroid Cancer Cells Journal of Surgical Research. 179: 244. DOI: 10.1016/J.Jss.2012.10.458 |
0.444 |
|
2012 |
Bucur O, Stancu AL, Khosravi-Far R, Almasan A. Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications. Cell Death & Disease. 3: e263. PMID 22297295 DOI: 10.1038/Cddis.2012.2 |
0.394 |
|
2011 |
Singh A, Plati J, Khosravi-Far R. Harnessing the tumor suppressor function of FOXO as an alternative therapeutic approach in cancer. Current Drug Targets. 12: 1311-21. PMID 21443464 DOI: 10.2174/138945011796150271 |
0.392 |
|
2011 |
Kazerounian S, Duquette M, Reyes MA, Lawler JT, Song K, Perruzzi C, Primo L, Khosravi-Far R, Bussolino F, Rabinovitz I, Lawler J. Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase. Blood. 117: 4658-66. PMID 21378271 DOI: 10.1182/Blood-2010-09-305284 |
0.312 |
|
2011 |
Plati J, Bucur O, Khosravi-Far R. Apoptotic cell signaling in cancer progression and therapy. Integrative Biology. 3: 279-296. PMID 21340093 DOI: 10.1039/C0Ib00144A |
0.488 |
|
2011 |
Dewar R, Chen ST, Yeckes-Rodin H, Miller K, Khosravi-Far R. Bortezomib treatment causes remission in a Ph+ALL patient and reveals FoxO as a theranostic marker. Cancer Biology & Therapy. 11: 552-558. PMID 21282974 DOI: 10.4161/Cbt.11.6.14675 |
0.342 |
|
2011 |
Sandra F, Khosravi-Far R. Phosphorylated-Survivin at Ser81 Induced Protein Kinase A (PKA): A Back Loop The Indonesian Biomedical Journal. 3: 138. DOI: 10.18585/Inabj.V3I2.145 |
0.39 |
|
2010 |
Weisberg E, Choi HG, Ray A, Barrett R, Zhang J, Sim T, Zhou W, Seeliger M, Cameron M, Azam M, Fletcher JA, Debiec-Rychter M, Mayeda M, Moreno D, Kung AL, ... ... Khosravi-Far R, et al. Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants. Blood. 115: 4206-16. PMID 20299508 DOI: 10.1182/Blood-2009-11-251751 |
0.301 |
|
2010 |
Singh A, Ye M, Bucur O, Zhu S, Tanya Santos M, Rabinovitz I, Wei W, Gao D, Hahn WC, Khosravi-Far R. Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. Molecular Biology of the Cell. 21: 1140-52. PMID 20110348 DOI: 10.1091/Mbc.E09-09-0795 |
0.369 |
|
2010 |
Sandra F, Khosravi-Far R. Survivin S81A Enhanced TRAIL's Activity in Inducing Apoptosis The Indonesian Biomedical Journal. 2: 7-113. DOI: 10.18585/Inabj.V2I3.124 |
0.47 |
|
2010 |
Singh A, Ye M, Song K, Bucur O, Khosravi-Far R. Abstract 4514: Proteasome inhibition causes regression of leukemia in part through regulation of forkhead tumor suppressors Cancer Research. 70: 4514-4514. DOI: 10.1158/1538-7445.Am10-4514 |
0.456 |
|
2010 |
Jin T, Kurakin A, Song K, Wang J, Santos T, Khosravi-Far R. Abstract 2909: ApoFLIP: A bioactive peptide that restarts the apoptotic machinery in cancer cells Cancer Research. 70: 2909-2909. DOI: 10.1158/1538-7445.Am10-2909 |
0.439 |
|
2010 |
Bucur O, Stancu AL, Petrescu SM, Khosravi-Far R. Abstract 205: Bortezomib and paclitaxel synergistically induce apoptosis in chronic myelogenous leukemia cells Cancer Research. 70: 205-205. DOI: 10.1158/1538-7445.Am10-205 |
0.411 |
|
2009 |
Jagani Z, Song K, Kutok JL, Dewar MR, Melet A, Santos T, Grassian A, Ghaffari S, Wu C, Yeckes-Rodin H, Rodin HY, Ren R, Miller K, Khosravi-Far R. Proteasome inhibition causes regression of leukemia and abrogates BCR-ABL-induced evasion of apoptosis in part through regulation of forkhead tumor suppressors. Cancer Research. 69: 6546-55. PMID 19654305 DOI: 10.1158/0008-5472.Can-09-0605 |
0.462 |
|
2009 |
Ren B, Song K, Parangi S, Jin T, Ye M, Humphreys R, Duquette M, Zhang X, Benhaga N, Lawler J, Khosravi-Far R. A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR. Cancer Research. 69: 3856-65. PMID 19366809 DOI: 10.1158/0008-5472.Can-08-2940 |
0.44 |
|
2008 |
Esposti MD, Tour J, Ouasti S, Ivanova S, Matarrese P, Malorni W, Khosravi-Far R. Fas Death Receptor Enhances Endocytic Membrane Traffic Converging into the Golgi Region Molecular Biology of the Cell. 20: 600-615. PMID 19037097 DOI: 10.1091/Mbc.E08-09-0925 |
0.351 |
|
2008 |
Song K, Mariappan R, Khosravi-Far R. Analysis of TNF-related apoptosis-inducing ligand in vivo through bone marrow transduction and transplantation. Methods in Enzymology. 446: 315-31. PMID 18603131 DOI: 10.1016/S0076-6879(08)01619-4 |
0.346 |
|
2008 |
Khosravi-Far R, Zakeri Z, Lockshin RA, Piacentini M. Methods in enzymolology book on cell death. Methods in Enzymology. 446: xxi-xxii. PMID 18603112 DOI: 10.1016/S0076-6879(08)01626-1 |
0.325 |
|
2008 |
Ndebele K, Gona P, Jin TG, Benhaga N, Chalah A, Degli-Esposti M, Khosravi-Far R. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced mitochondrial pathway to apoptosis and caspase activation is potentiated by phospholipid scramblase-3. Apoptosis : An International Journal On Programmed Cell Death. 13: 845-56. PMID 18491232 DOI: 10.1007/S10495-008-0219-4 |
0.441 |
|
2008 |
Plati J, Bucur O, Khosravi-Far R. Dysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunities. Journal of Cellular Biochemistry. 104: 1124-49. PMID 18459149 DOI: 10.1002/jcb.21707 |
0.34 |
|
2008 |
Matarrese P, Manganelli V, Garofalo T, Tinari A, Gambardella L, Ndebele K, Khosravi-Far R, Sorice M, Esposti MD, Malorni W. Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells. Biochemical Journal. 413: 467-478. PMID 18442358 DOI: 10.1042/Bj20071704 |
0.414 |
|
2008 |
Jagani Z, Khosravi-Far R. Cancer stem cells and impaired apoptosis. Advances in Experimental Medicine and Biology. 615: 331-44. PMID 18437901 DOI: 10.1007/978-1-4020-6554-5_15 |
0.369 |
|
2008 |
Melet A, Song K, Bucur O, Jagani Z, Grassian AR, Khosravi-Far R. Apoptotic pathways in tumor progression and therapy. Advances in Experimental Medicine and Biology. 615: 47-79. PMID 18437891 DOI: 10.1007/978-1-4020-6554-5_4 |
0.419 |
|
2008 |
Chalah A, Khosravi-Far R. The mitochondrial death pathway. Advances in Experimental Medicine and Biology. 615: 25-45. PMID 18437890 DOI: 10.1007/978-1-4020-6554-5_3 |
0.372 |
|
2008 |
Jagani Z, Singh A, Khosravi-Far R. FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis. Biochimica Et Biophysica Acta. 1785: 63-84. PMID 17980712 DOI: 10.1016/J.Bbcan.2007.10.003 |
0.459 |
|
2007 |
Wang L, Dutta SK, Kojima T, Xu X, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. Plos One. 2: e1161. PMID 18000534 DOI: 10.1371/Journal.Pone.0001161 |
0.352 |
|
2007 |
Zhang X, Zhang L, Yang H, Huang X, Otu H, Libermann TA, DeWolf WC, Khosravi-Far R, Olumi AF. c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cells. Cancer Research. 67: 9425-34. PMID 17909052 DOI: 10.1158/0008-5472.Can-07-1310 |
0.42 |
|
2007 |
Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. The Embo Journal. 26: 3410-22. PMID 17599062 DOI: 10.1038/Sj.Emboj.7601779 |
0.423 |
|
2007 |
Ouasti S, Matarrese P, Paddon R, Khosravi-Far R, Sorice M, Tinari A, Malorni W, Esposti MD. Death receptor ligation triggers membrane scrambling between Golgi and mitochondria Cell Death & Differentiation. 14: 453-461. PMID 17008914 DOI: 10.1038/Sj.Cdd.4402043 |
0.403 |
|
2007 |
Zhang X, Yang H, Zhang L, Huang X, Otu H, Libermann T, Khosravi-Far R, DeWolf WC, Olumi AF. 661: C-FOS Promotes Trail-Induced Apoptosis by Repressing C-Flip(L) Journal of Urology. 177: 222-222. DOI: 10.1016/S0022-5347(18)30901-7 |
0.348 |
|
2006 |
Song K, Benhaga N, Anderson RL, Khosravi-Far R. Transduction of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand into Hematopoietic Cells Leads to Inhibition of Syngeneic Tumor Growth In vivo Cancer Research. 66: 6304-6311. PMID 16778207 DOI: 10.1158/0008-5472.Can-05-3501 |
0.422 |
|
2006 |
Ren B, Yee KO, Lawler J, Khosravi-Far R. Regulation of tumor angiogenesis by thrombospondin-1. Biochimica Et Biophysica Acta. 1765: 178-88. PMID 16406676 DOI: 10.1016/J.Bbcan.2005.11.002 |
0.366 |
|
2006 |
Abe K, Kurakin A, Mohseni-Maybodi M, Kay B, Khosravi-Far R. The complexity of TNF-related apoptosis-inducing ligand Annals of the New York Academy of Sciences. 926: 52-63. PMID 11193041 DOI: 10.1111/J.1749-6632.2000.Tb05598.X |
0.466 |
|
2005 |
Sandra F, Esposti MD, Ndebele K, Gona P, Knight D, Rosenquist M, Khosravi-Far R. Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Alters Mitochondrial Membrane Lipids Cancer Research. 65: 8286-8297. PMID 16166305 DOI: 10.1158/0008-5472.Can-04-1913 |
0.439 |
|
2005 |
Goonesinghe A, Mundy ES, Smith M, Khosravi-Far R, Martinou J, Esposti MD. Pro-apoptotic Bid induces membrane perturbation by inserting selected lysolipids into the bilayer. Biochemical Journal. 387: 109-118. PMID 15500442 DOI: 10.1042/Bj20041389 |
0.41 |
|
2004 |
Khosravi-Far R, Esposti MD. Death receptor signals to mitochondria. Cancer Biology & Therapy. 3: 1051-1057. PMID 15640619 DOI: 10.4161/Cbt.3.11.1173 |
0.432 |
|
2004 |
Jin TG, Kurakin A, Benhaga N, Abe K, Mohseni M, Sandra F, Song K, Kay BK, Khosravi-Far R. Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5. The Journal of Biological Chemistry. 279: 55594-601. PMID 15485835 DOI: 10.1074/Jbc.M401056200 |
0.424 |
|
2004 |
Zhang X, Jin TG, Yang H, DeWolf WC, Khosravi-Far R, Olumi AF. Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer. Cancer Research. 64: 7086-91. PMID 15466204 DOI: 10.1158/0008-5472.Can-04-1498 |
0.433 |
|
2004 |
Parangi S, Ben R, Zhang X, Galardi E, Duquette M, Peruzzi C, Lawler J, Khosravi-Far R. Proapoptotic and survival signaling pathways plays a role in thrombospondin type I repeat mediated apoptosis in human microvascular endothelial cells Journal of the American College of Surgeons. 199: 85-86. DOI: 10.1016/J.Jamcollsurg.2004.05.185 |
0.47 |
|
2003 |
Ghaffari S, Jagani Z, Kitidis C, Lodish HF, Khosravi-Far R. Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 100: 6523-8. PMID 12750477 DOI: 10.1073/Pnas.0731871100 |
0.459 |
|
2002 |
Pandey A, Dan I, Kristiansen TZ, Watanabe NM, Voldby J, Kajikawa E, Khosravi-Far R, Blagoev B, Mann M. Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain. Oncogene. 21: 3939-48. PMID 12032833 DOI: 10.1038/Sj.Onc.1205478 |
0.362 |
|
2001 |
Pal S, Datta K, Khosravi-Far R, Mukhopadhyay D. Role of Protein Kinase Cζ in Ras-mediated Transcriptional Activation of Vascular Permeability Factor/Vascular Endothelial Growth Factor Expression Journal of Biological Chemistry. 276: 2395-2403. PMID 11060301 DOI: 10.1074/Jbc.M007818200 |
0.343 |
|
1996 |
Whitehead IP, Khosravi-Far R, Kirk H, Trigo-Gonzalez G, Der CJ, Kayt R. Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors Journal of Biological Chemistry. 271: 18643-18650. PMID 8702517 DOI: 10.1074/Jbc.271.31.18643 |
0.32 |
|
1996 |
Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Molecular and Cellular Biology. 16: 3923-33. PMID 8668210 DOI: 10.1128/Mcb.16.7.3923 |
0.351 |
|
1996 |
Chu Y, Solski PA, Khosravi-Far R, Der CJ, Kelly K. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. The Journal of Biological Chemistry. 271: 6497-501. PMID 8626452 DOI: 10.1074/Jbc.271.11.6497 |
0.361 |
|
1995 |
Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Molecular and Cellular Biology. 15: 6443-53. PMID 7565796 DOI: 10.1128/Mcb.15.11.6443 |
0.337 |
|
1994 |
Khosravi-Far R, Der CJ. The Ras signal transduction pathway. Cancer Metastasis Reviews. 13: 67-89. PMID 8143346 DOI: 10.1007/Bf00690419 |
0.389 |
|
1994 |
Khosravi-Far R, Chrzanowska-Wodnicka M, Solski PA, Eva A, Burridge K, Der CJ. Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic ras Molecular and Cellular Biology. 14: 6848-6857. PMID 7935402 DOI: 10.1128/Mcb.14.10.6848 |
0.356 |
|
1992 |
Tisdale EJ, Bourne JR, Khosravi-Far R, Der CJ, Balch WE. GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex. The Journal of Cell Biology. 119: 749-61. PMID 1429835 DOI: 10.1083/Jcb.119.4.749 |
0.311 |
|
1991 |
Khosravi-Far R, Lutz RJ, Cox AD, Conroy L, Bourne JR, Sinensky M, Balch WE, Buss JE, Der CJ. Isoprenoid modification of rab proteins terminating in CC or CXC motifs. Proceedings of the National Academy of Sciences of the United States of America. 88: 6264-8. PMID 1648736 DOI: 10.1073/Pnas.88.14.6264 |
0.305 |
|
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