Miriam Falzon - Publications

Affiliations: 
University of Texas Medical Branch, Galveston, TX 
Area:
Pharmacology, Oncology, Molecular Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mrazek AA, Bhatia V, Falzon M, Spratt H, Chao C, Hellmich MR. Apigenin Decreases Acinar Cell Damage in Pancreatitis. Pancreas. 48: 711-718. PMID 31091220 DOI: 10.1097/Mpa.0000000000001310  0.321
2015 Bhatia V, Cao Y, Ko TC, Falzon M. Parathyroid Hormone-Related Protein Interacts With the Transforming Growth Factor-β/Bone Morphogenetic Protein-2/Gremlin Signaling Pathway to Regulate Proinflammatory and Profibrotic Mediators in Pancreatic Acinar and Stellate Cells. Pancreas. PMID 26495794 DOI: 10.1097/Mpa.0000000000000522  0.348
2015 Rastellini C, Han S, Bhatia V, Cao Y, Liu K, Gao X, Ko TC, Greeley GH, Falzon M. Induction of chronic pancreatitis by pancreatic duct ligation activates BMP2, apelin, and PTHrP expression in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 309: G554-65. PMID 26229008 DOI: 10.1152/Ajpgi.00076.2015  0.324
2015 Staloch D, Gao X, Liu K, Xu M, Feng X, Aronson JF, Falzon M, Greeley GH, Rastellini C, Chao C, Hellmich MR, Cao Y, Ko TC. Gremlin is a key pro-fibrogenic factor in chronic pancreatitis. Journal of Molecular Medicine (Berlin, Germany). PMID 26141517 DOI: 10.1007/S00109-015-1308-9  0.319
2015 Falzon M, Bhatia V. Role of Parathyroid Hormone-Related Protein Signaling in Chronic Pancreatitis. Cancers. 7: 1091-108. PMID 26095761 DOI: 10.3390/Cancers7020826  0.338
2015 Bhatia V, Falzon M. Restoration of the anti-proliferative and anti-migratory effects of 1,25-dihydroxyvitamin D by silibinin in vitamin D-resistant colon cancer cells. Cancer Letters. 362: 199-207. PMID 25846868 DOI: 10.1016/J.Canlet.2015.03.042  0.415
2015 Mrazek AA, Porro LJ, Bhatia V, Falzon M, Spratt H, Zhou J, Chao C, Hellmich MR. Apigenin inhibits pancreatic stellate cell activity in pancreatitis. The Journal of Surgical Research. 196: 8-16. PMID 25799526 DOI: 10.1016/J.Jss.2015.02.032  0.364
2014 Ellis J, Falzon M, Emrick T, Figueiredo ML. Imaging cytokine targeting to the tumor/bone microenvironment in vivo. Human Gene Therapy. Clinical Development. 25: 200-1. PMID 25495534 DOI: 10.1089/Humc.2014.085  0.331
2014 Bhatia V, Rastellini C, Han S, Aronson JF, Greeley GH, Falzon M. Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G533-49. PMID 25035110 DOI: 10.1152/Ajpgi.00428.2013  0.418
2014 Mrazek A, Falzon M, Chen H, Zhou J, Bohanon F, Porro L, Bhatia V, Wang X, Hellmich M, Chao C. Apigenin Inhibits the Pro-Inflammatory and Pro-Fibrogenic Responses in Both Acinar Cells and Pancreatic Stellate Cells in Experimentally Induced Pancreatitis Journal of Surgical Research. 186: 688. DOI: 10.1016/J.Jss.2013.11.1018  0.38
2013 Cao Y, Zhang W, Gao X, Zhang G, Falzon M, Townsend CM, Hellmich MR, Ko TC. PTHrP is a novel mediator for TGF-β-induced apoptosis. Regulatory Peptides. 184: 40-6. PMID 23499802 DOI: 10.1016/J.Regpep.2013.03.024  0.345
2013 Bhatia V, Mula RV, Falzon M. Parathyroid hormone-related protein regulates integrin α6 and β4 levels via transcriptional and post-translational pathways. Experimental Cell Research. 319: 1419-30. PMID 23499737 DOI: 10.1016/J.Yexcr.2013.03.003  0.417
2012 Bhatia V, Kim SO, Aronson JF, Chao C, Hellmich MR, Falzon M. Role of parathyroid hormone-related protein in the pro-inflammatory and pro-fibrogenic response associated with acute pancreatitis. Regulatory Peptides. 175: 49-60. PMID 22280800 DOI: 10.1016/J.Regpep.2012.01.006  0.403
2011 Bhatia V, Mula RV, Falzon M. 1,25-Dihydroxyvitamin D(3) regulates PTHrP expression via transcriptional, post-transcriptional and post-translational pathways. Molecular and Cellular Endocrinology. 342: 32-40. PMID 21664243 DOI: 10.1016/J.Mce.2011.05.025  0.513
2010 Mula RV, Bhatia V, Falzon M. PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1. Cancer Letters. 298: 119-27. PMID 20637541 DOI: 10.1016/J.Canlet.2010.06.009  0.521
2009 Bhatia V, Saini MK, Falzon M. Nuclear PTHrP targeting regulates PTHrP secretion and enhances LoVo cell growth and survival Regulatory Peptides. 158: 149-155. PMID 19616583 DOI: 10.1016/J.Regpep.2009.07.008  0.555
2009 Bhatia V, Mula RV, Weigel NL, Falzon M. Parathyroid hormone-related protein regulates cell survival pathways via integrin alpha6beta4-mediated activation of phosphatidylinositol 3-kinase/Akt signaling. Molecular Cancer Research : McR. 7: 1119-31. PMID 19584267 DOI: 10.1158/1541-7786.Mcr-08-0568  0.553
2009 Bhatia V, Saini MK, Shen X, Bi LX, Qiu S, Weigel NL, Falzon M. EB1089 inhibits the parathyroid hormone-related protein-enhanced bone metastasis and xenograft growth of human prostate cancer cells. Molecular Cancer Therapeutics. 8: 1787-98. PMID 19584236 DOI: 10.1158/1535-7163.Mct-09-0064  0.608
2007 Shen X, Rychahou PG, Evers BM, Falzon M. PTHrP increases xenograft growth and promotes integrin alpha6beta4 expression and Akt activation in colon cancer. Cancer Letters. 258: 241-52. PMID 17964713 DOI: 10.1016/J.Canlet.2007.09.010  0.467
2007 Shen X, Mula RV, Li J, Weigel NL, Falzon M. PTHrP contributes to the anti-proliferative and integrin alpha6beta4-regulating effects of 1,25-dihydroxyvitamin D(3). Steroids. 72: 930-8. PMID 17904173 DOI: 10.1016/J.Steroids.2007.08.003  0.546
2007 Shen X, Mula RV, Evers BM, Falzon M. Increased cell survival, migration, invasion, and Akt expression in PTHrP-overexpressing LoVo colon cancer cell lines. Regulatory Peptides. 141: 61-72. PMID 17276526 DOI: 10.1016/J.Regpep.2006.12.017  0.528
2006 Shen X, Falzon M. PTH-related protein upregulates integrin alpha6beta4 expression and activates Akt in breast cancer cells. Experimental Cell Research. 312: 3822-34. PMID 16965770 DOI: 10.1016/J.Yexcr.2006.08.011  0.451
2006 Sepulveda VA, Weigel NL, Falzon M. Prostate cancer cell type-specific involvement of the VDR and RXR in regulation of the human PTHrP gene via a negative VDRE. Steroids. 71: 102-15. PMID 16243370 DOI: 10.1016/J.Steroids.2005.08.009  0.637
2005 Shen X, Falzon M. PTH-related protein enhances LoVo colon cancer cell proliferation, adhesion, and integrin expression. Regulatory Peptides. 125: 17-27. PMID 15582709 DOI: 10.1016/J.Regpep.2004.07.025  0.544
2004 Narayanan R, Sepulveda VA, Falzon M, Weigel NL. The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific. The Journal of Biological Chemistry. 279: 47298-310. PMID 15331595 DOI: 10.1074/Jbc.M404101200  0.431
2004 Shen X, Qian L, Falzon M. PTH-related protein enhances MCF-7 breast cancer cell adhesion, migration, and invasion via an intracrine pathway. Experimental Cell Research. 294: 420-33. PMID 15023531 DOI: 10.1016/J.Yexcr.2003.11.028  0.503
2003 Tovar Sepulveda VA, Falzon M. Prostate cancer cell type-specific regulation of the human PTHrP gene via a negative VDRE. Molecular and Cellular Endocrinology. 204: 51-64. PMID 12850281 DOI: 10.1016/S0303-7207(03)00148-5  0.74
2003 Shen X, Falzon M. Parathyroid hormone-related protein upregulates integrin expression via an intracrine pathway in PC-3 prostate cancer cells. Regulatory Peptides. 113: 17-29. PMID 12686457 DOI: 10.1016/S0167-0115(02)00293-8  0.535
2003 Shen X, Falzon M. PTH-related protein modulates PC-3 prostate cancer cell adhesion and integrin subunit profile. Molecular and Cellular Endocrinology. 199: 165-77. PMID 12581888 DOI: 10.1016/S0303-7207(02)00287-3  0.584
2002 Tovar Sepulveda VA, Falzon M. Regulation of PTH-related protein gene expression by vitamin D in PC-3 prostate cancer cells. Molecular and Cellular Endocrinology. 190: 115-24. PMID 11997185 DOI: 10.1016/S0303-7207(02)00003-5  0.737
2002 Tovar Sepulveda VA, Falzon M. Parathyroid hormone-related protein enhances PC-3 prostate cancer cell growth via both autocrine/paracrine and intracrine pathways. Regulatory Peptides. 105: 109-20. PMID 11891011 DOI: 10.1016/S0167-0115(02)00007-1  0.741
2002 Tovar Sepulveda VA, Shen X, Falzon M. Intracrine PTHrP protects against serum starvation-induced apoptosis and regulates the cell cycle in MCF-7 breast cancer cells. Endocrinology. 143: 596-606. PMID 11796515 DOI: 10.1210/Endo.143.2.8645  0.707
2001 Ye Y, Falzon M, Seitz PK, Cooper CW. Overexpression of parathyroid hormone-related protein promotes cell growth in the rat intestinal cell line IEC-6 Regulatory Peptides. 99: 169-174. PMID 11384779 DOI: 10.1016/S0167-0115(01)00248-8  0.496
2001 Ye Y, Wang C, Du P, Falzon M, Seitz PK, Cooper CW. Overexpression of parathyroid hormone-related protein enhances apoptosis in the rat intestinal cell line, IEC-6 Endocrinology. 142: 1906-1914. PMID 11316756 DOI: 10.1210/Endo.142.5.8121  0.485
2001 Wu C, Seitz PK, Falzon M. Single-column purification and bio-characterization of recombinant human parathyroid hormone-related protein (1-139). Molecular and Cellular Endocrinology. 170: 163-74. PMID 11162900 DOI: 10.1016/S0303-7207(00)00323-3  0.423
2000 Falzon M, Du P. Enhanced growth of MCF-7 breast cancer cells overexpressing PTH-related peptide Endocrinology. 141: 1882-1892. PMID 10803599 DOI: 10.1210/En.141.5.1882  0.524
1998 Falzon M, Zong J. The noncalcemic vitamin D analogs EB1089 and 22-oxacalcitriol suppress serum-induced parathyroid hormone-related peptide gene expression in a lung cancer cell line. Endocrinology. 139: 1046-53. PMID 9492037 DOI: 10.1210/Endo.139.3.5774  0.499
1997 Falzon M. The noncalcemic vitamin D analogues EB1089 and 22-oxacalcitriol interact with the vitamin D receptor and suppress parathyroid hormone-related peptide gene expression. Molecular and Cellular Endocrinology. 127: 99-108. PMID 9099905 DOI: 10.1016/S0303-7207(96)03994-9  0.433
1996 Falzon M. DNA sequences in the rat parathyroid hormone-related peptide gene responsible for 1,25-dihydroxyvitamin D3-mediated transcriptional repression. Molecular Endocrinology (Baltimore, Md.). 10: 672-81. PMID 8776727 DOI: 10.1210/Mend.10.6.8776727  0.399
1996 Falzon M. Serum stimulation of parathyroid hormone-related peptide gene expression in ROS 17/2.8 osteosarcoma cells through transcriptional and posttranscriptional mechanisms. Endocrinology. 137: 3681-8. PMID 8756533 DOI: 10.1210/Endo.137.9.8756533  0.395
1990 Schuller HM, Falzon M, McMahon JB. Metabolic activation and biological effects of nitrosamines in the mammalian lung. Pharmacology & Therapeutics. 46: 95-103. PMID 2181493 DOI: 10.1016/0163-7258(90)90037-3  0.322
1988 Falzon M, Kuff EL. Multiple protein-binding sites in an intracisternal A particle long terminal repeat. Journal of Virology. 62: 4070-4077. PMID 3139894 DOI: 10.1128/Jvi.62.11.4070-4077.1988  0.36
1987 Hegedus TJ, Falzon M, Margaretten N, Gazdar AF, Schuller HM. Inhibition of N-diethylnitrosamine metabolism by human lung cancer cell lines with features of well differentiated pulmonary endocrine cells. Biochemical Pharmacology. 36: 3339-43. PMID 2823818 DOI: 10.1016/0006-2952(87)90308-X  0.414
1986 Falzon M, McMahon JB, Gazdar AF, Schuller HM. Preferential metabolism of N-nitrosodiethylamine by two cell lines derived from human pulmonary adenocarcinomas. Carcinogenesis. 7: 17-22. PMID 3080252 DOI: 10.1093/Carcin/7.1.17  0.36
1986 Falzon M, McMahon JB, Schuller HM. Xenobiotic-metabolizing enzyme activity in human non-small-cell derived lung cancer cell lines. Biochemical Pharmacology. 35: 563-8. PMID 3004505 DOI: 10.1016/0006-2952(86)90348-5  0.34
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