| Year |
Citation |
Score |
| 2018 |
Ramsey ML, Talbert E, Ahn D, Bekaii-Saab T, Badi N, Bloomston PM, Conwell DL, Cruz-Monserrate Z, Dillhoff M, Farren MR, Hinton A, Krishna SG, Lesinski GB, Mace T, Manilchuk A, ... ... Guttridge D, et al. Circulating interleukin-6 is associated with disease progression, but not cachexia in pancreatic cancer. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. PMID 30497874 DOI: 10.1016/J.Pan.2018.11.002 |
0.315 |
|
| 2018 |
Hong HK, Maury E, Ramsey KM, Perelis M, Marcheva B, Omura C, Kobayashi Y, Guttridge DC, Barish GD, Bass J. Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice. Genes & Development. PMID 30366905 DOI: 10.1101/Gad.319228.118 |
0.319 |
|
| 2018 |
Peterson JM, Wang DJ, Shettigar V, Roof SR, Canan BD, Bakkar N, Shintaku J, Gu JM, Little SC, Ratnam NM, Londhe P, Lu L, Gaw CE, Petrosino JM, Liyanarachchi S, ... ... Guttridge DC, et al. NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model. Nature Communications. 9: 3431. PMID 30143619 DOI: 10.1038/S41467-018-05910-1 |
0.306 |
|
| 2018 |
Damrauer JS, Stadler ME, Acharyya S, Baldwin AS, Couch ME, Guttridge DC. Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia. European Journal of Translational Myology. 28: 7590. PMID 29991992 DOI: 10.4081/Ejtm.2018.7590 |
0.316 |
|
| 2018 |
Chen S, Bonifati S, Qin Z, St Gelais C, Kodigepalli KM, Barrett BS, Kim SH, Antonucci JM, Ladner KJ, Buzovetsky O, Knecht KM, Xiong Y, Yount JS, Guttridge DC, Santiago ML, et al. SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610295 DOI: 10.1073/Pnas.1801213115 |
0.301 |
|
| 2017 |
Ratnam NM, Peterson JM, Talbert EE, Ladner KJ, Rajasekera PV, Schmidt CR, Dillhoff ME, Swanson BJ, Haverick E, Kladney RD, Williams TM, Leone GW, Wang DJ, Guttridge DC. NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development. The Journal of Clinical Investigation. PMID 28891811 DOI: 10.1172/Jci91561 |
0.328 |
|
| 2016 |
Kim SH, Ezhilarasan R, Phillips E, Gallego-Perez D, Sparks A, Taylor D, Ladner K, Furuta T, Sabit H, Chhipa R, Cho JH, Mohyeldin A, Beck S, Kurozumi K, Kuroiwa T, ... ... Guttridge D, et al. Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner. Cancer Cell. 29: 201-213. PMID 26859459 DOI: 10.1016/J.Ccell.2016.01.005 |
0.432 |
|
| 2016 |
Ratnam N, Wang D, Guttridge D. Abstract 3232: NF-κB regulates suppression of macrophage activity during tumor initiation Immunology. 76: 3232-3232. DOI: 10.1158/1538-7445.Am2016-3232 |
0.406 |
|
| 2015 |
Yang J, Talbert E, Elnaggar O, Rajasekera P, Mace T, Farren M, Che Z, Swanson B, Young G, Haverick E, Timmers C, Bloomston M, Bekaii-Saab T, Guttridge D, Lesinski G. Abstract 4695: Dual targeting of MEK and PI3K pathways can act via tumor-intrinsic mechanisms to overcome resistance and tumor-extrinsic mechanisms to modulate immunity and limit cancer cachexia Cancer Research. 75: 4695-4695. DOI: 10.1158/1538-7445.Am2015-4695 |
0.362 |
|
| 2015 |
Yang J, Elnaggar O, Mace T, Farren M, Young G, Lee P, Keenan K, Che Z, Kaufman J, Guttridge D, Carbone D, Timmers C, Bekaii-Saab T, Lesinski G. Abstract 2656: Combined inhibition of MEK and PI3K elicits anti-tumor activity in human cholangiocarcinoma Cancer Research. 75: 2656-2656. DOI: 10.1158/1538-7445.Am2015-2656 |
0.356 |
|
| 2014 |
Wang DJ, Ratnam NM, Byrd JC, Guttridge DC. NF-κB functions in tumor initiation by suppressing the surveillance of both innate and adaptive immune cells. Cell Reports. 9: 90-103. PMID 25263557 DOI: 10.1016/j.celrep.2014.08.049 |
0.309 |
|
| 2014 |
Tseng Y, Kulp S, Lai I, He W, Bundschuh R, Frankhouser D, Yan P, Guttridge D, Marcucci G, Chen C, Bekaii-Saab T. Abstract 5540: Preclinical investigation of the novel histone deacetylase (HDAC) inhibitor AR-42 in the treatment of cancer-induced cachexia Cancer Research. 74: 5540-5540. DOI: 10.1158/1538-7445.Am2014-5540 |
0.379 |
|
| 2013 |
Parker MH, von Maltzahn J, Bakkar N, Al-Joubori B, Ishibashi J, Guttridge D, Rudnicki MA. Retraction: MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation. Skeletal Muscle. 3: 15. PMID 23870549 DOI: 10.1186/2044-5040-3-15 |
0.396 |
|
| 2013 |
Shintaku J, Guttridge DC. Reining in nuclear factor-kappaB in skeletal muscle disorders. Current Opinion in Clinical Nutrition and Metabolic Care. 16: 251-7. PMID 23493016 DOI: 10.1097/MCO.0b013e3283600e79 |
0.309 |
|
| 2013 |
Wu C, Fernandez SA, Criswell T, Chidiac TA, Guttridge D, Villalona-Calero M, Bekaii-Saab TS. Disrupting cytokine signaling in pancreatic cancer: a phase I/II study of etanercept in combination with gemcitabine in patients with advanced disease. Pancreas. 42: 813-8. PMID 23429495 DOI: 10.1097/Mpa.0B013E318279B87F |
0.326 |
|
| 2012 |
Parker MH, von Maltzahn J, Bakkar N, Al-Joubori B, Ishibashi J, Guttridge D, Rudnicki MA. MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation. Skeletal Muscle. 2: 6. PMID 22541644 DOI: 10.1186/2044-5040-2-6 |
0.372 |
|
| 2011 |
Wang Y, Mo X, Piper MG, Wang H, Parinandi NL, Guttridge D, Marsh CB. M-CSF induces monocyte survival by activating NF-κB p65 phosphorylation at Ser276 via protein kinase C. Plos One. 6: e28081. PMID 22216091 DOI: 10.1371/Journal.Pone.0028081 |
0.415 |
|
| 2011 |
Shadfar S, Couch ME, McKinney KA, Weinstein LJ, Yin X, RodrÃguez JE, Guttridge DC, Willis M. Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo. Nutrition and Cancer. 63: 749-62. PMID 21660860 DOI: 10.1080/01635581.2011.563032 |
0.329 |
|
| 2010 |
Acharyya S, Sharma SM, Cheng AS, Ladner KJ, He W, Kline W, Wang H, Ostrowski MC, Huang TH, Guttridge DC. TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy. Plos One. 5: e12479. PMID 20814569 DOI: 10.1371/Journal.Pone.0012479 |
0.333 |
|
| 2010 |
Bakkar N, Guttridge DC. NF-kappaB signaling: a tale of two pathways in skeletal myogenesis. Physiological Reviews. 90: 495-511. PMID 20393192 DOI: 10.1152/physrev.00040.2009 |
0.379 |
|
| 2010 |
Dahlman JM, Bakkar N, He W, Guttridge DC. NF-kappaB functions in stromal fibroblasts to regulate early postnatal muscle development. The Journal of Biological Chemistry. 285: 5479-87. PMID 20018862 DOI: 10.1074/jbc.M109.075606 |
0.338 |
|
| 2009 |
Chen SS, Raval A, Johnson AJ, Hertlein E, Liu TH, Jin VX, Sherman MH, Liu SJ, Dawson DW, Williams KE, Lanasa M, Liyanarachchi S, Lin TS, Marcucci G, Pekarsky Y, ... ... Guttridge DC, et al. Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 106: 13433-8. PMID 19666576 DOI: 10.1073/Pnas.0906455106 |
0.578 |
|
| 2008 |
Peterson JM, Guttridge DC. Skeletal muscle diseases, inflammation, and NF-κB signaling: Insights and opportunities for therapeutic intervention International Reviews of Immunology. 27: 375-387. PMID 18853344 DOI: 10.1080/08830180802302389 |
0.304 |
|
| 2008 |
Bakkar N, Wang J, Ladner KJ, Wang H, Dahlman JM, Carathers M, Acharyya S, Rudnicki MA, Hollenbach AD, Guttridge DC. IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis. The Journal of Cell Biology. 180: 787-802. PMID 18299349 DOI: 10.1083/jcb.200707179 |
0.347 |
|
| 2008 |
Waldman WJ, Williams MV, Lemeshow S, Binkley P, Guttridge D, Kiecolt-Glaser JK, Knight DA, Ladner KJ, Glaser R. Epstein-Barr virus-encoded dUTPase enhances proinflammatory cytokine production by macrophages in contact with endothelial cells: evidence for depression-induced atherosclerotic risk. Brain, Behavior, and Immunity. 22: 215-23. PMID 17845840 DOI: 10.1016/J.Bbi.2007.07.007 |
0.307 |
|
| 2007 |
Madhavan S, Anghelina M, Sjostrom D, Dossumbekova A, Guttridge DC, Agarwal S. Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 6246-54. PMID 17947700 DOI: 10.4049/Jimmunol.179.9.6246 |
0.316 |
|
| 2007 |
Cannon T, Couch M, Yin X, Guttridge D, Lai V, Shores C. Comparison of animal models for head and neck cancer cachexia. The Laryngoscope. 117: 2152-8. PMID 17921906 DOI: 10.1097/Mlg.0B013E3181453658 |
0.318 |
|
| 2007 |
Wang H, Hertlein E, Bakkar N, Sun H, Acharyya S, Wang J, Carathers M, Davuluri R, Guttridge DC. NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes. Molecular and Cellular Biology. 27: 4374-87. PMID 17438126 DOI: 10.1128/Mcb.02020-06 |
0.624 |
|
| 2007 |
George J, Cannon T, Lai V, Richey L, Zanation A, Hayes DN, Shores C, Guttridge D, Couch M. Cancer cachexia syndrome in head and neck cancer patients: Part II. Pathophysiology. Head & Neck. 29: 497-507. PMID 17390378 DOI: 10.1002/Hed.20630 |
0.311 |
|
| 2007 |
Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, ... ... Guttridge DC, et al. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. The Journal of Clinical Investigation. 117: 889-901. PMID 17380205 DOI: 10.1172/Jci30556 |
0.325 |
|
| 2006 |
Sarkar A, Duncan M, Hart J, Hertlein E, Guttridge DC, Wewers MD. ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions. Journal of Immunology (Baltimore, Md. : 1950). 176: 4979-86. PMID 16585594 DOI: 10.4049/Jimmunol.176.8.4979 |
0.591 |
|
| 2005 |
Kosuri KV, Bekaii-Saab T, Bender J, Criswell T, Kane Y, Chidiac T, Young D, Guttridge D, Caligiuri M, Villalona-Calero M. Disrupting TNF signaling in pancreatic cancer: A phase I/II clinical study in patients with advanced disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4103. PMID 27944791 DOI: 10.1200/Jco.2005.23.16_Suppl.4103 |
0.383 |
|
| 2005 |
Hertlein E, Wang J, Ladner KJ, Bakkar N, Guttridge DC. RelA/p65 regulation of IkappaBbeta. Molecular and Cellular Biology. 25: 4956-68. PMID 15923614 DOI: 10.1128/Mcb.25.12.4956-4968.2005 |
0.593 |
|
| 2004 |
Hartman MG, Lu D, Kim ML, Kociba GJ, Shukri T, Buteau J, Wang X, Frankel WL, Guttridge D, Prentki M, Grey ST, Ron D, Hai T. Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Molecular and Cellular Biology. 24: 5721-32. PMID 15199129 DOI: 10.1128/Mcb.24.13.5721-5732.2004 |
0.342 |
|
| 2003 |
Ladner KJ, Caligiuri MA, Guttridge DC. Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene products. The Journal of Biological Chemistry. 278: 2294-303. PMID 12431991 DOI: 10.1074/Jbc.M207129200 |
0.388 |
|
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