| Year |
Citation |
Score |
| 2017 |
Galick HA, Marsden CG, Kathe S, Dragon JA, Volk L, Nemec AA, Wallace SS, Prakash A, Doublié S, Sweasy JB. The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation. Oncotarget. 8: 85883-85895. PMID 29156764 DOI: 10.18632/Oncotarget.20716 |
0.417 |
|
| 2017 |
Eckenroth BE, Towle-Weicksel JB, Nemec AA, Murphy DL, Sweasy JB, Doublié S. Remote mutations induce functional changes in active site residues of human DNA polymerase beta. Biochemistry. PMID 28402631 DOI: 10.1021/Acs.Biochem.6B01287 |
0.338 |
|
| 2017 |
Nemec AA, Abriola L, Merkel JS, deStanchina E, DeVeaux M, Zelterman D, Glazer PM, Sweasy JB. DNA polymerase beta germline variant confers cellular response to cisplatin therapy. Molecular Cancer Research : McR. PMID 28074003 DOI: 10.1158/1541-7786.Mcr-16-0227-T |
0.366 |
|
| 2016 |
Nemec AA, Bush KB, Towle-Weicksel JB, Taylor BF, Schulz V, Weidhaas J, Tuck DP, Sweasy JB. Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-associated R438W DNA Polymerase Lambda Protein. Molecular Cancer Research : McR. PMID 27621267 DOI: 10.1158/1541-7786.Mcr-16-0209 |
0.4 |
|
| 2015 |
Rozacky J, Nemec AA, Sweasy JB, Kidane D. Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks. Oncotarget. 6: 24474-87. PMID 26090616 DOI: 10.18632/Oncotarget.4426 |
0.412 |
|
| 2014 |
Sjolund A, Nemec AA, Paquet N, Prakash A, Sung P, Doublié S, Sweasy JB. A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. Plos Genetics. 10: e1004753. PMID 25375110 DOI: 10.1371/Journal.Pgen.1004753 |
0.419 |
|
| 2014 |
Nemec AA, Murphy DL, Donigan KA, Sweasy JB. The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency. The Journal of Biological Chemistry. 289: 13708-16. PMID 24668809 DOI: 10.1074/Jbc.M114.550400 |
0.409 |
|
| 2012 |
Yamtich J, Nemec AA, Keh A, Sweasy JB. A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation. Plos Genetics. 8: e1003052. PMID 23144635 DOI: 10.1371/Journal.Pgen.1003052 |
0.403 |
|
| 2012 |
Donigan KA, Sun KW, Nemec AA, Murphy DL, Cong X, Northrup V, Zelterman D, Sweasy JB. Human POLB gene is mutated in high percentage of colorectal tumors. The Journal of Biological Chemistry. 287: 23830-9. PMID 22577134 DOI: 10.1074/Jbc.M111.324947 |
0.386 |
|
| 2012 |
Nemec AA, Donigan KA, Murphy DL, Jaeger J, Sweasy JB. Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation. The Journal of Biological Chemistry. 287: 23840-9. PMID 22573322 DOI: 10.1074/Jbc.M112.362111 |
0.433 |
|
| 2011 |
Nemec AA, Donigan KA, Murphy DL, Jaeger J, Sweasy JB. Abstract B37: A DNA polymerase beta gene harboring the colon cancer-associated G231D variant increases the sensitivity of cells to chemotherapeutic agents and induces cellular transformation Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-B37 |
0.399 |
|
| 2010 |
Nemec AA, Wallace SS, Sweasy JB. Variant base excision repair proteins: contributors to genomic instability. Seminars in Cancer Biology. 20: 320-8. PMID 20955798 DOI: 10.1016/J.Semcancer.2010.10.010 |
0.388 |
|
| 2010 |
Nemec AA, Zubritsky LM, Barchowsky A. Chromium(VI) stimulates Fyn to initiate innate immune gene induction in human airway epithelial cells. Chemical Research in Toxicology. 23: 396-404. PMID 19994902 DOI: 10.1021/Tx900365U |
0.391 |
|
| 2009 |
Nemec AA, Barchowsky A. Signal transducer and activator of transcription 1 (STAT1) is essential for chromium silencing of gene induction in human airway epithelial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 212-23. PMID 19403854 DOI: 10.1093/Toxsci/Kfp084 |
0.417 |
|
| 2009 |
Nemec AA, Leikauf GD, Pitt BR, Wasserloos KJ, Barchowsky A. Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 41: 69-75. PMID 19097988 DOI: 10.1165/Rcmb.2008-0409Oc |
0.483 |
|
| 2007 |
O'Hara KA, Vaghjiani RJ, Nemec AA, Klei LR, Barchowsky A. Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck. The Biochemical Journal. 402: 261-9. PMID 17078813 DOI: 10.1042/Bj20061427 |
0.379 |
|
| 2006 |
O'Hara KA, Nemec AA, Alam J, Klei LR, Mossman BT, Barchowsky A. Chromium (VI) inhibits heme oxygenase-1 expression in vivo and in arsenic-exposed human airway epithelial cells. Journal of Cellular Physiology. 209: 113-21. PMID 16775837 DOI: 10.1002/Jcp.20710 |
0.4 |
|
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