| Year |
Citation |
Score |
| 2023 |
Clevenger MH, Karami AL, Carlson DA, Kahrilas PJ, Gonsalves N, Pandolfino JE, Winter DR, Whelan KA, Tétreault MP. Suprabasal cells retain progenitor cell identity programs in eosinophilic esophagitis-driven basal cell hyperplasia. Jci Insight. PMID 37672481 DOI: 10.1172/jci.insight.171765 |
0.305 |
|
| 2023 |
Kabir MF, Jackson JL, Fuller AD, Gathuka L, Karami AL, Conde DG, Klochkova A, Mu A, Cai KQ, Klein-Szanto AJ, Muir AB, Whelan KA. Diclofenac exhibits cytotoxic activity associated with metabolic alterations and p53 induction in ESCC cell lines and decreases ESCC tumor burden in vivo. Carcinogenesis. PMID 37014121 DOI: 10.1093/carcin/bgad019 |
0.336 |
|
| 2020 |
Karakasheva TA, Kijima T, Shimonosono M, Maekawa H, Sahu V, Gabre JT, Cruz-Acuña R, Giroux V, Sangwan V, Whelan KA, Natsugoe S, Yoon AJ, Philipone E, Klein-Szanto AJ, Ginsberg GG, et al. Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids. Current Protocols in Stem Cell Biology. 53: e109. PMID 32294323 DOI: 10.1002/Cpsc.109 |
0.371 |
|
| 2020 |
Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, ... Whelan KA, et al. Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Current Protocols in Stem Cell Biology. 52: e106. PMID 32105412 DOI: 10.1002/Cpsc.106 |
0.356 |
|
| 2020 |
Klochkova A, Patel K, Murray MG, Hamilton KE, Whelan KA. Su1116 HIGH AUTOPHAGIC VESICLE CONTENT IDENTIFIES A NOVEL ESOPHAGEAL BASAL CELL POPULATION WITH STEM CELL PROPERTIES Gastroenterology. 158: S-513-S-514. DOI: 10.1016/S0016-5085(20)31967-3 |
0.328 |
|
| 2020 |
Saxena R, Murray MG, Klochkova A, Kabir MF, Gang J, Beccari T, Klein-Szanto A, Muir AB, Whelan KA. 929 INTERLEUKIN13-MEDIATED DISRUPTION OF MITOCHONDRIAL BIOLOGY CONTRIBUTES TO IMPAIRED SQUAMOUS CELL DIFFERENTIATION IN EOSINOPHILIC ESOPHAGITIS Gastroenterology. 158: S-185. DOI: 10.1016/S0016-5085(20)31146-X |
0.352 |
|
| 2019 |
Guha M, Srinivasan S, Sheehan MM, Kijima T, Ruthel G, Whelan K, Tanaka K, Klein-Szanto A, Chandramouleeswaran PM, Nakagawa H, Avadhani NG. Esophageal 3D organoids of mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition. Oncotarget. 10: 6245-6259. PMID 31692873 DOI: 10.18632/Oncotarget.27264 |
0.345 |
|
| 2019 |
Saxena R, Klochkova A, Murray MG, Kabir MF, Samad S, Beccari T, Gang J, Patel K, Hamilton KE, Whelan KA. Roles for Autophagy in Esophageal Carcinogenesis: Implications for Improving Patient Outcomes. Cancers. 11. PMID 31683722 DOI: 10.3390/Cancers11111697 |
0.373 |
|
| 2019 |
Whelan KA, Godwin BC, Wilkins B, Elci OU, Benitez A, DeMarshall M, Sharma M, Gross J, Klein-Szanto AJ, Liacouras CA, Dellon ES, Spergel JM, Falk GW, Muir AB, Nakagawa H. Persistent Basal Cell Hyperplasia is Associated with Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 31499251 DOI: 10.1016/J.Cgh.2019.08.055 |
0.313 |
|
| 2019 |
Reichenbach ZW, Murray MG, Saxena R, Farkas D, Karassik EG, Klochkova A, Patel K, Tice C, Hall TM, Gang J, Parkman HP, Ward SJ, Tétreault MP, Whelan KA. Clinical and translational advances in esophageal squamous cell carcinoma. Advances in Cancer Research. 144: 95-135. PMID 31349905 DOI: 10.1016/Bs.Acr.2019.05.004 |
0.308 |
|
| 2019 |
Chatterji P, Williams PA, Whelan KA, Samper FC, Andres SF, Simon LA, Parham LR, Mizuno R, Lundsmith ET, Lee DS, Liang S, Wijeratne HS, Marti S, Chau L, Giroux V, et al. Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1. Embo Reports. PMID 31061170 DOI: 10.15252/Embr.201847074 |
0.362 |
|
| 2019 |
Shaverdashvili K, Padlo J, Weinblatt D, Jia Y, Jiang W, Rao D, Laczkó D, Whelan KA, Lynch JP, Muir AB, Katz JP. KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF. Plos One. 14: e0215746. PMID 30998758 DOI: 10.1371/Journal.Pone.0215746 |
0.431 |
|
| 2019 |
Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, et al. Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells. Cellular and Molecular Gastroenterology and Hepatology. 7: 73-91. PMID 30510992 DOI: 10.1016/J.Jcmgh.2018.09.003 |
0.388 |
|
| 2019 |
Shimonosono M, Chandramouleeswaran PM, Hara T, Karakasheva T, Kijima T, Guha M, Correnti J, Whelan KA, Ohashi S, Tanaka K, Avadhani NG, Carr R, Nakagawa H. Mo1737 – Aldh2 and Autophaghy-Mediated Redox Homeostasis Limit the Alcohol-Induced Expansion of Esophageal Cancer Stem Cells Gastroenterology. 156: S-827. DOI: 10.1016/S0016-5085(19)39021-3 |
0.335 |
|
| 2019 |
Kijima T, Shimonosono M, Chandramouleeswaran PM, Karakasheva T, Tang Q, Kasagi Y, Wada M, Muir AB, Whelan KA, Klein-Szanto A, Natsugoe S, Rustgi A, Nakagawa H. 529 – 3D Organoids Reveal the Expansion of Neoplastic Cell Heterogeneity During Development and Progression of Esophageal Squamous Cell Carcinoma Gastroenterology. 156: S-107. DOI: 10.1016/S0016-5085(19)37059-3 |
0.358 |
|
| 2019 |
Hall T, Murray MG, Gang J, Moneger A, Benitez A, DeMarshall M, Klein-Szanto A, Falk GW, Muir AB, Whelan KA. 169 – Interleukin-13-Mediated Release of Mitochondrial Dna from Esophageal Epithelial Cells: A Novel Biomarker for Eosinophilic Esophagitis Gastroenterology. 156: S-40-S-41. DOI: 10.1016/S0016-5085(19)36882-9 |
0.312 |
|
| 2018 |
Kasagi Y, Dods K, Wang JX, Chandramouleeswaran PM, Benitez AJ, Gambanga F, Kluger J, Ashorobi T, Gross J, Tobias JW, Klein-Szanto AJ, Spergel JM, Cianferoni A, Falk GW, Whelan KA, et al. Fibrostenotic eosinophilic esophagitis may reflect epithelial lysyl oxidase induction by fibroblasts-derived tumor necrosis factor-α. The Journal of Allergy and Clinical Immunology. PMID 30578874 DOI: 10.1016/J.Jaci.2018.10.067 |
0.322 |
|
| 2018 |
Parham LR, Williams PA, Chatterji P, Whelan KA, Hamilton KE. RNA regulons are essential in intestinal homeostasis. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 30520692 DOI: 10.1152/Ajpgi.00403.2017 |
0.39 |
|
| 2018 |
Whelan KA, Muir AB, Nakagawa H. Esophageal 3D Culture Systems as Modeling Tools in Esophageal Epithelial Pathobiology and Personalized Medicine. Cellular and Molecular Gastroenterology and Hepatology. 5: 461-478. PMID 29713660 DOI: 10.1016/J.Jcmgh.2018.01.011 |
0.308 |
|
| 2018 |
Hall TM, Tétreault MP, Hamilton KE, Whelan KA. Autophagy as a cytoprotective mechanism in esophageal squamous cell carcinoma. Current Opinion in Pharmacology. 41: 12-19. PMID 29677645 DOI: 10.1016/J.Coph.2018.04.003 |
0.398 |
|
| 2018 |
Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, et al. The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes. Cellular and Molecular Gastroenterology and Hepatology. 5: 333-352. PMID 29552622 DOI: 10.1016/J.Jcmgh.2017.12.013 |
0.353 |
|
| 2018 |
Chandramouleeswaran PM, Whelan KA, Engel N, Correnti J, Tanaka K, Srinivasan S, Guha M, Carr R, Klein-Szanto AJ, Kalyanaraman B, Chen C, Mochly-Rosen D, Avadhani NG, Nakagawa H. Abstract 5061: ALDH2 restricts esophageal stem/progenitor cell expansion via autophagy under alcohol-induced mitochondrial stress Cancer Research. 78: 5061-5061. DOI: 10.1158/1538-7445.Am2018-5061 |
0.395 |
|
| 2018 |
Tanaka K, Kijima T, Chandramouleeswaran PM, Whelan KA, Kasagi Y, Shimonosono M, Furukawa H, Hara T, Makino T, Yamasaki M, Klein-Szanto AJ, Natsugoe S, Mori M, Doki Y, Nakagawa H. Abstract 5026: Alcohol enriches therapy-resistant cancer cells with high autophagy, CD44 expression and tumor initiating capability Tumor Biology. DOI: 10.1158/1538-7445.Am2018-5026 |
0.362 |
|
| 2018 |
Whelan KA, Chandramouleeswaran P, Sharma M, Benitez A, DeMarshall M, Klein-Szanto A, Spergel J, Falk GW, Muir AB, Nakagawa H. 463 - Rapamycin-Mediated Autophagy Activation Ameliorates Eoeassociated Alterations in Epithelial Tissue Architecture Gastroenterology. 154: S-108. DOI: 10.1016/S0016-5085(18)30797-2 |
0.329 |
|
| 2018 |
Kasagi Y, Whelan KA, Chandramouleeswaran P, Sharma M, Wang J, Benitez A, DeMarshall M, Klein-Szanto A, Giroux V, Hamilton KE, Falk GW, Spergel J, Nakagawa H, Muir AB. 460 - Inflammatory Cytokines Diminish Notch Signaling to Drive Reactive Epithelial Changes in Eosinophilic Esophagitis Gastroenterology. 154: S-107. DOI: 10.1016/S0016-5085(18)30794-7 |
0.323 |
|
| 2017 |
Natsuizaka M, Whelan KA, Kagawa S, Tanaka K, Giroux V, Chandramouleeswaran PM, Long A, Sahu V, Darling DS, Que J, Yang Y, Katz JP, Wileyto EP, Basu D, Kita Y, et al. Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma. Nature Communications. 8: 1758. PMID 29170450 DOI: 10.1038/S41467-017-01500-9 |
0.418 |
|
| 2017 |
Maehara O, Suda G, Natsuizaka M, Ohnishi S, Komatsu Y, Sato F, Nakai M, Sho T, Morikawa K, Ogawa K, Shimazaki T, Kimura M, Asano A, Fujimoto Y, Ohashi S, ... ... Whelan KA, et al. Fibroblast growth factor-2-mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma. Carcinogenesis. PMID 28927233 DOI: 10.1093/Carcin/Bgx095 |
0.492 |
|
| 2017 |
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, et al. Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. The Journal of Clinical Investigation. PMID 28481227 DOI: 10.1172/Jci88941 |
0.394 |
|
| 2017 |
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene. PMID 28414310 DOI: 10.1038/Onc.2017.102 |
0.384 |
|
| 2017 |
Kasagi Y, Gambanga F, Benitez A, Whelan KA, Kluger J, Gross J, Chandramouleeswaran P, Spergel J, Cianferoni A, DeMarshall M, Falk GW, Nakagawa H, Muir AB. Lysyl Oxidase is a Novel Fibrostenotic Indicator in Eosinophilic Esophagitis Induced VIA the TNFΑ-TGFÎ' Axis in the Epithelial-Fibroblast Crosstalk Gastroenterology. 152: S875. DOI: 10.1016/S0016-5085(17)32995-5 |
0.376 |
|
| 2017 |
Whelan KA, Tanaka K, Kijima T, Ohashi S, Chandramouleeswaran P, Sharma M, Kita Y, Klein-Szanto A, Ginsberg GG, Muto M, Natsugoe S, Rustgi AK, Nakagawa H. 3D Organoids Reveal the Autophagy-CD44 Cell Axis in Esophageal Cancer Therapy Resistance Gastroenterology. 152: S169. DOI: 10.1016/S0016-5085(17)30883-1 |
0.34 |
|
| 2016 |
Facompre ND, Harmeyer KM, Sole X, Kabraji S, Belden Z, Sahu V, Whelan K, Tanaka K, Weinstein GS, Montone KT, Roesch A, Gimotty PA, Herlyn M, Rustgi AK, Nakagawa H, et al. JARID1B enables transit between distinct states of the stem-like cell population in oral cancers. Cancer Research. PMID 27488530 DOI: 10.1158/0008-5472.Can-15-3377 |
0.446 |
|
| 2016 |
Kim SY, Ebbert K, Cordeiro MH, Romero MM, Whelan KA, Suarez AA, Woodruff T, Kurita T. Constitutive activation of PI3K in oocytes induces ovarian granulosa cell tumors. Cancer Research. PMID 27197196 DOI: 10.1158/0008-5472.Can-15-3358 |
0.318 |
|
| 2016 |
Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, et al. Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut. PMID 26884425 DOI: 10.1136/Gutjnl-2015-310341 |
0.385 |
|
| 2016 |
Tanaka K, Whelan KA, Rustgi NL, Chandramouleeswaran PM, Naganuma S, Kagawa S, Natsuizaka M, Kita Y, Natsugoe S, Jianwen Q, Basu D, Klein-Szanto AJ, Bass A, Diehl JA, Nakagawa H. Abstract 2678: Notch1 regulates epithelial-mesenchymal transition and tumor-initiating capability in esophageal squamous-cell carcinoma Cancer Research. 76: 2678-2678. DOI: 10.1158/1538-7445.Am2016-2678 |
0.467 |
|
| 2016 |
Whelan K, Giroux V, Merves J, Godwin B, Masterson JC, Benitez A, Que J, Muir AB, Furuta G, Spergel J, Nakagawa H. Mo1208 Esophageal Epithelial Autophagy Flux Regulates Eosinophilic Esophagitis Disease Activity Gastroenterology. 150: S671. DOI: 10.1016/S0016-5085(16)32283-1 |
0.335 |
|
| 2015 |
Muir AB, Dods K, Henry SJ, Benitez AJ, Lee D, Whelan KA, DeMarshall M, Hammer DA, Falk G, Wells RG, Spergel J, Nakagawa H, Wang ML. Eosinophilic Esophagitis Associated Chemical and Mechanical Microenvironment Shapes Esophageal Fibroblast Behavior. Journal of Pediatric Gastroenterology and Nutrition. PMID 26727658 DOI: 10.1097/Mpg.0000000000001100 |
0.323 |
|
| 2015 |
Kong J, Whelan KA, Laczkó D, Dang B, Caro Monroig A, Soroush A, Falcone J, Amaravadi RK, Rustgi AK, Ginsberg GG, Falk GW, Nakagawa H, Lynch JP. Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress. Molecular Carcinogenesis. PMID 26373456 DOI: 10.1002/Mc.22406 |
0.397 |
|
| 2015 |
Maehara O, Sato F, Natsuizaka M, Asano A, Kubota Y, Itoh J, Tsunematsu S, Terashita K, Tsukuda Y, Nakai M, Sho T, Suda G, Morikawa K, Ogawa K, Chuma M, ... ... Whelan KA, et al. A pivotal role of Krüppel-like factor 5 in regulation of cancer stem-like cells in hepatocellular carcinoma. Cancer Biology & Therapy. 16: 1453-61. PMID 26176896 DOI: 10.1080/15384047.2015.1070992 |
0.309 |
|
| 2015 |
Srinivasan S, Guha M, Dong DW, Whelan KA, Ruthel G, Uchikado Y, Natsugoe S, Nakagawa H, Avadhani NG. Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming. Oncogene. PMID 26148236 DOI: 10.1038/Onc.2015.227 |
0.452 |
|
| 2015 |
Sato F, Kubota Y, Natsuizaka M, Maehara O, Hatanaka Y, Marukawa K, Terashita K, Suda G, Ohnishi S, Shimizu Y, Komatsu Y, Ohashi S, Kagawa S, Kinugasa H, Whelan KA, et al. EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition. Cancer Biology & Therapy. 16: 933-40. PMID 25897987 DOI: 10.1080/15384047.2015.1040959 |
0.433 |
|
| 2015 |
Long A, Giroux V, Whelan KA, Hamilton KE, Tétreault MP, Tanaka K, Lee JS, Klein-Szanto AJ, Nakagawa H, Rustgi AK. WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma. Carcinogenesis. 36: 598-606. PMID 25795715 DOI: 10.1093/Carcin/Bgv025 |
0.459 |
|
| 2015 |
Nakagawa H, Whelan K, Lynch JP. Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models. Best Practice & Research. Clinical Gastroenterology. 29: 3-16. PMID 25743452 DOI: 10.1016/J.Bpg.2014.11.001 |
0.316 |
|
| 2015 |
Kinugasa H, Whelan KA, Tanaka K, Natsuizaka M, Long A, Guo A, Chang S, Kagawa S, Srinivasan S, Guha M, Yamamoto K, St Clair DK, Avadhani NG, Diehl JA, Nakagawa H. Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene. PMID 25659582 DOI: 10.1038/Onc.2014.449 |
0.463 |
|
| 2015 |
Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, et al. Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities. Oncogene. 34: 2347-59. PMID 24931169 DOI: 10.1038/onc.2014.169 |
0.352 |
|
| 2015 |
Natsuizaka M, Kagawa S, Whelan K, Ohashi S, Ohnishi S, Suda G, Sakamoto N, Rustgi AK, Nakagawa H. Abstract A74: TGF-β in tumor microenvironment changes a switch of Notch1-mediated signaling to maintain cancer stem-like cells in esophageal squamous cell carcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A74 |
0.442 |
|
| 2015 |
Whelan KA, Kinugasa H, Tanaka K, Srinivasan S, Guha M, Clair DS, Klein-Szanto A, Avadhani N, Diehl A, Rustgi A, Nakagawa H. Abstract 1254: Mitochondrial SOD2 regulates EMT and cancer stem cell-like cell populations Cancer Research. 75: 1254-1254. DOI: 10.1158/1538-7445.Am2015-1254 |
0.381 |
|
| 2015 |
Whelan KA, Tanaka K, Kinugasa H, Natsuizaka M, Que J, Amaravadi RK, Klein-Szanto AJ, Diehl JA, Rustgi AK, Nakagawa H. Tu1997 Mitochondrial-Targeted Autophagy Promotes Cancer Stem Cell Expansion in ESCC Gastroenterology. 148: S-955. DOI: 10.1016/S0016-5085(15)33263-7 |
0.352 |
|
| 2015 |
Long A, Giroux V, Whelan KA, Klein-Szanto AJ, Nakagawa H, Rustgi AK. Su1961 Wnt10a Promotes a More Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma Gastroenterology. 148: S-561. DOI: 10.1016/S0016-5085(15)31890-4 |
0.326 |
|
| 2015 |
Kong J, Whelan KA, Dang B, Caro-Monroig A, Soroush A, Amaravadi RK, Falk GW, Ginsberg GG, Nakagawa H, Lynch JP. Sa1882 Autophagic Regulation of Oxidative Stress Promotes Esophageal Epithelial Cell Survival in Response to Acid Injury: Implications for Barrett's Esophagus Initiation and Progression Gastroenterology. 148: S-345-S-346. DOI: 10.1016/S0016-5085(15)31156-2 |
0.321 |
|
| 2015 |
Whelan KA, Merves J, Muir A, Guo A, Chandramouleeswaran PM, Dods KK, DeMarshall M, Que J, Spergel J, Wang M, Falk GW, Nakagawa H. 526 Autophagy Is an Epithelial Cytoprotective Mechanism in Esophageal Epithelial Cells in Response to Eosinophilic Esophagitis-Associated Inflammation Gastroenterology. 148: S-104-S-105. DOI: 10.1016/S0016-5085(15)30358-9 |
0.396 |
|
| 2015 |
Tanaka K, Whelan KA, Noguchi C, Peake JD, Grothusen G, Anandarajan V, Amanuma Y, Ohashi S, Chiba T, Muto M, Noguchi E, Nakagawa H. 381 ALDH2 and Autophagy May Cooperate to Alleviate Acetaldehyde-Mediated DNA Damage and Cytotoxicity in Fission Yeast and Esophageal Epithelial Cells Gastroenterology. 148: S-79. DOI: 10.1016/S0016-5085(15)30275-4 |
0.379 |
|
| 2015 |
Amanuma Y, Ohashi S, Kikuchi O, Nakai Y, Miyamoto S, Tanaka K, Whelan KA, Nakagawa H, Chiba T, Matsuda T, Muto M. 380 Alcohol Induces ALDH2 As a Novel Cytoprotective Mechanism to Suppress Acetaldehyde-Derived DNA Adduct Formation in Esophageal Epithelial Cells Gastroenterology. 148: S-79. DOI: 10.1016/S0016-5085(15)30274-2 |
0.38 |
|
| 2015 |
Muir A, Dods KK, Whelan KA, Merves J, Benitez AJ, DeMarshall M, Spergel J, Falk GW, Wells R, Wang M, Nakagawa H. 204 Epithelial Lysyl Oxidase Is an Early Mediator of Fibrotic Remodeling in Eosinophilic Esophagitis Gastroenterology. 148: S-52. DOI: 10.1016/S0016-5085(15)30181-5 |
0.353 |
|
| 2014 |
Natsuizaka M, Kinugasa H, Kagawa S, Whelan KA, Naganuma S, Subramanian H, Chang S, Nakagawa KJ, Rustgi NL, Kita Y, Natsugoe S, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, et al. IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment. American Journal of Cancer Research. 4: 29-41. PMID 24482736 |
0.385 |
|
| 2014 |
Whelan KA, Kagawa S, Guo A, Natsuizaka M, Kinugasa H, Ohashi S, Kita Y, Natsugoe S, Naganuma S, Klein-Szanto AJ, Amaravadi RK, Rustgi AK, Nakagawa H. Tu1699 Autophagy Regulates Esophageal Cancer Stem Cell Phenotypic Plasticity by Targeting Mitochondria and Oxidative Stress Gastroenterology. 146: S-821. DOI: 10.1016/S0016-5085(14)62976-0 |
0.357 |
|
| 2014 |
Natsuizaka M, Kaimila B, Kubota Y, Hatanaka Y, Marukawa K, Terashita K, Satou F, Ohnishi S, Suda G, Ohashi S, Kagawa S, Whelan KA, Rustgi AK, Nakagawa H, Sakamoto N. Tu1698 EGFR Inhibitors Eliminate Esophageal Cancer Stem Cells by Suppressing Epithelial-Mesenchymal Transition Gastroenterology. 146: S-821. DOI: 10.1016/S0016-5085(14)62975-9 |
0.357 |
|
| 2013 |
Whelan KA, Schwab LP, Karakashev SV, Franchetti L, Johannes GJ, Seagroves TN, Reginato MJ. The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance. The Journal of Biological Chemistry. 288: 15865-77. PMID 23585570 DOI: 10.1074/Jbc.M112.426999 |
0.729 |
|
| 2013 |
Kagawa S, Nakagawa K, Natsuizaka M, Kinugasa H, Whelan KA, Chang S, Subramanian H, Ohashi S, Klein-Szanto AJ, Gimotty PA, Diehl JA, Herlyn M, Nakagawa H, Rustgi AK. 677 Inactivation of the Retinoblastoma Protein-Dependent Senescence Checkpoint Functions Permits Notch1 to Gain Oncogenic Tumor Promoting Activity Gastroenterology. 144: S-124. DOI: 10.1016/S0016-5085(13)60444-8 |
0.46 |
|
| 2013 |
Natsuizaka M, Kagawa S, Whelan KA, Chang S, Kinugasa H, Ohashi S, Naganuma S, Sakamoto N, Klein-Szanto AJ, Gimotty PA, Diehl JA, Herlyn M, Rustgi AK, Nakagawa H. 237 Transforming Growth Factor-β and Notch1 Cooperate to Repress NOTCH3 to Facilitate Epithelial-Mesenchymal Transition and Tumor Initiating Capability in Esophageal Squamous Cell Carcinoma Gastroenterology. 144: S-52. DOI: 10.1016/S0016-5085(13)60183-3 |
0.374 |
|
| 2012 |
Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhoades B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, Klein-Szanto AJ, Nakagawa H. Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma. American Journal of Cancer Research. 2: 459-75. PMID 22860235 |
0.358 |
|
| 2012 |
Natsuizaka M, Chang S, Kagawa S, Naganuma S, Ohashi S, Whelan KA, Wong GS, Vega ME, Yang Y, Gimotty PA, Diehl JA, Herlyn M, Nakagawa H. 252 CD44 Defines Highly Plastic Esophageal Squamous Cancer Cells With Tumor Initiating Capabilities Gastroenterology. 142: S-59. DOI: 10.1016/S0016-5085(12)60230-3 |
0.468 |
|
| 2012 |
Natsuizaka M, Naganuma S, Kagawa S, Ohashi S, Whelan KA, Chang S, Rhim AD, Klein-Szanto AJ, Diehl JA, Herlyn M, Nakagawa H. 251 A Functional Interplay Between TGF- and Notch Signaling Determines Esophageal Cancer Cell Fates Gastroenterology. 142: S-59. DOI: 10.1016/S0016-5085(12)60229-7 |
0.461 |
|
| 2011 |
Whelan KA, Reginato MJ. Surviving without oxygen: Hypoxia regulation of mammary morphogenesis and anoikis Cell Cycle. 10: 2287-2294. PMID 21670595 DOI: 10.4161/Cc.10.14.16532 |
0.704 |
|
| 2011 |
Whelan KA. Abstract 2062: HIF-1 is required for ErbB2-mediated anoikis resistance Cancer Research. 71: 2062-2062. DOI: 10.1158/1538-7445.Am2011-2062 |
0.526 |
|
| 2010 |
Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ, Reginato MJ. Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis. Molecular Biology of the Cell. 21: 3829-37. PMID 20861305 DOI: 10.1091/Mbc.E10-04-0353 |
0.733 |
|
| 2010 |
Haenssen KK, Caldwell SA, Shahriari KS, Jackson SR, Whelan KA, Klein-Szanto AJ, Reginato MJ. ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells. Journal of Cell Science. 123: 1373-82. PMID 20332114 DOI: 10.1242/Jcs.050906 |
0.64 |
|
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