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Katherine M. Aird, Ph.D. - Publications

Affiliations: 
2010 Pathology Duke University, Durham, NC 
Area:
Cell Biology
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56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chang C, Cheng YY, Kamlapurkar S, White SR, Tang PW, Elhaw AT, Javed Z, Aird KM, Mythreye K, Phaëton R, Hempel N. GPX3 supports ovarian cancer tumor progression and promotes expression of GDF15. Biorxiv : the Preprint Server For Biology. PMID 38352432 DOI: 10.1101/2024.01.24.577037  0.312
2024 Chang C, Cheng YY, Kamlapurkar S, White S, Tang PW, Elhaw AT, Javed Z, Aird KM, Mythreye K, Phaëton R, Hempel N. GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15. Gynecologic Oncology. 185: 8-16. PMID 38342006 DOI: 10.1016/j.ygyno.2024.02.004  0.315
2023 Bapat J, Yamamoto TM, Woodruff ER, Qamar L, Mikeska RG, Aird KM, Watson ZL, Brubaker LW, Bitler BG. CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR. Cancer Gene Therapy. PMID 38030811 DOI: 10.1038/s41417-023-00703-1  0.354
2023 Sharrow AC, Ho M, Buj R, Blenman KRM, Buckanovich R, Aird KM, Wu L. Tumor-Associated Macrophages Expand Chemoresistant, Ovarian Cancer Stem-Like Cells. Biorxiv : the Preprint Server For Biology. PMID 37503008 DOI: 10.1101/2023.07.17.549067  0.321
2023 Oesterreich S, Aird KM. Senescence and Immunotherapy: Redundant Immunomodulatory Pathways Promote Resistance. Cancer Immunology Research. OF1-OF4. PMID 36826438 DOI: 10.1158/2326-6066.CIR-23-0051  0.336
2022 Huang Z, Chen CW, Buj R, Tangudu NK, Fang RS, Leon KE, Dahl ES, Varner EL, von Krusenstiern E, Cole AR, Snyder NW, Aird KM. ATM inhibition drives metabolic adaptation via induction of macropinocytosis. The Journal of Cell Biology. 222. PMID 36399181 DOI: 10.1083/jcb.202007026  0.39
2022 Veenstra JP, Bittencourt LFF, Aird KM. The Senescence-Associated Secretory Phenotype in Ovarian Cancer Dissemination. American Journal of Physiology. Cell Physiology. PMID 35584328 DOI: 10.1152/ajpcell.00049.2022  0.356
2021 Leon KE, Buj R, Lesko E, Dahl ES, Chen CW, Tangudu NK, Imamura-Kawasawa Y, Kossenkov AV, Hobbs RP, Aird KM. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. The Journal of Cell Biology. 220. PMID 34037658 DOI: 10.1083/jcb.202008101  0.346
2021 Buj R, Leon KE, Anguelov MA, Aird KM. Suppression of p16 alleviates the senescence-associated secretory phenotype. Aging. 13. PMID 33550279 DOI: 10.18632/aging.202640  0.326
2020 Aronson MR, Dahl ES, Halle JA, Simonson AW, Gogal RA, Glick AB, Aird KM, Medina SH. Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers. Cellular and Molecular Bioengineering. 13: 447-461. PMID 33184577 DOI: 10.1007/S12195-020-00626-Z  0.36
2020 Chen CW, Buj R, Dahl ES, Leon KE, Aird KM. ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells. Heliyon. 6: e05097. PMID 33024871 DOI: 10.1016/j.heliyon.2020.e05097  0.364
2020 Cole AJ, Iyengar M, Panesso-Gómez S, O'Hayer PJ, Chan DK, Delgoffe GM, Aird KM, Yoon E, Bai S, Buckanovich RJ. NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. Jci Insight. PMID 32182216 DOI: 10.1172/Jci.Insight.131486  0.475
2020 Zhao B, Liu P, Fukumoto T, Nacarelli T, Fatkhutdinov N, Wu S, Lin J, Aird KM, Tang HY, Liu Q, Speicher DW, Zhang R. Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence. Nature Communications. 11: 908. PMID 32075966 DOI: 10.1038/S41467-020-14652-Y  0.308
2020 Dahl ES, Leon KE, Chen C, Jia Q, Buj R, Snyder NW, Aird KM. Abstract 1378: Targeting the metabolic-epigenetic axis to sensitize HR-proficient ovarian cancer to PARP inhibitors Cancer Research. 80: 1378-1378. DOI: 10.1158/1538-7445.Am2020-1378  0.46
2019 Kim YS, Gupta Vallur P, Jones VM, Worley BL, Shimko S, Shin DH, Crawford LC, Chen CW, Aird KM, Abraham T, Shepherd TG, Warrick JI, Lee NY, Phaeton R, Mythreye K, et al. Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells. Oncogene. PMID 31723239 DOI: 10.1038/S41388-019-1097-7  0.51
2019 Buj R, Chen CW, Dahl ES, Leon KE, Kuskovsky R, Maglakelidze N, Navaratnarajah M, Zhang G, Doan MT, Jiang H, Zaleski M, Kutzler L, Lacko H, Lu Y, Mills GB, ... ... Aird KM, et al. Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. Cell Reports. 28: 1971-1980.e8. PMID 31433975 DOI: 10.1016/J.Celrep.2019.07.084  0.439
2019 Dahl ES, Buj R, Leon KE, Newell JM, Imamura Y, Bitler BG, Snyder NW, Aird KM. Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer. Molecular Cancer Research : McR. PMID 31110157 DOI: 10.1158/1541-7786.Mcr-18-1233  0.502
2019 Nacarelli T, Lau L, Fukumoto T, Zundell J, Fatkhutdinov N, Wu S, Aird KM, Iwasaki O, Kossenkov AV, Schultz D, Noma KI, Baur JA, Schug Z, Tang HY, Speicher DW, et al. NAD metabolism governs the proinflammatory senescence-associated secretome. Nature Cell Biology. PMID 30778219 DOI: 10.1038/S41556-019-0287-4  0.405
2019 Leon KE, Aird KM. Jumonji C Demethylases in Cellular Senescence. Genes. 10. PMID 30634491 DOI: 10.3390/Genes10010033  0.371
2019 Dahl ES, Snyder NW, Aird KM. Abstract GMM-022: IDH1 IS A PRO-SENESCENT THERAPY IN HIGH-GRADE SEROUS OVARIAN CANCER Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Gmm-022  0.483
2018 Worley BL, Kim YS, Mardini J, Zaman R, Leon KE, Vallur PG, Nduwumwami A, Warrick JI, Timmins PF, Kesterson JP, Phaëton R, Lee NY, Walter V, Endres L, Mythreye K, ... Aird KM, et al. GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment. Redox Biology. PMID 30509602 DOI: 10.1016/J.Redox.2018.11.009  0.436
2018 Singha B, Harper SL, Goldman AR, Bitler BG, Aird KM, Borowsky ME, Cadungog MG, Liu Q, Zhang R, Jean S, Drapkin R, Speicher DW. CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer. Scientific Reports. 8: 14725. PMID 30282979 DOI: 10.1038/S41598-018-32885-2  0.336
2018 Buj R, Aird KM. Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease. Frontiers in Endocrinology. 9: 177. PMID 29720963 DOI: 10.3389/Fendo.2018.00177  0.396
2017 Dahl ES, Aird KM. Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer. Frontiers in Oncology. 7: 291. PMID 29238697 DOI: 10.3389/Fonc.2017.00291  0.359
2017 Karakashev S, Aird KM. Ovarian cancer: how can resistance to chemotherapy be tackled? Future Oncology (London, England). 13: 2737-2739. PMID 29182383 DOI: 10.2217/Fon-2017-0235  0.355
2017 Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher Iii FJ, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nature Cell Biology. PMID 28737768 DOI: 10.1038/Ncb3582  0.376
2017 Bitler BG, Park PH, Hai Y, Aird KM, Wang Y, Huntsman DG, Cho KR, Christianson DW, Zhang R. Abstract AP25: INHIBITION OF HDAC ACTIVITY SELECTIVELY INHIBITS ARID1A–MUTATED OVARIAN CLEAR CELL CARCINOMA THROUGH A NOVEL P53 REGULATORY MECHANISM Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap25  0.476
2016 Bitler BG, Aird KM, Zhang R. Epigenetic synthetic lethality in ovarian clear cell carcinoma: EZH2 and ARID1A mutations. Molecular & Cellular Oncology. 3: e1032476. PMID 27308548 DOI: 10.1080/23723556.2015.1032476  0.311
2016 Fatkhutdinov N, Sproesser K, Krepler C, Liu Q, Brafford PA, Herlyn M, Aird KM, Zhang R. Targeting RRM2 and Mutant BRAF is a Novel Combinatorial Strategy for Melanoma. Molecular Cancer Research : McR. PMID 27297629 DOI: 10.1158/1541-7786.Mcr-16-0099  0.433
2016 Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, ... ... Aird KM, et al. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. PMID 27042933 DOI: 10.1038/Nature17392  0.388
2015 Zhu H, Ren S, Bitler BG, Aird KM, Tu Z, Skordalakes E, Zhu Y, Yan J, Sun Y, Zhang R. SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase. Cell Reports. PMID 26527005 DOI: 10.1016/J.Celrep.2015.09.083  0.367
2015 Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, Wen H, Liu Y, Wang C, Pestell RG, Aird KM, Kaelin WG, Liu XS, Zhang Q. EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. The Embo Journal. PMID 26492917 DOI: 10.15252/Embj.201591437  0.374
2015 Aird KM, Zhang R. ATM in senescence. Oncotarget. 6: 14729-30. PMID 26143490 DOI: 10.18632/Oncotarget.4411  0.487
2015 Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC. PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124089 DOI: 10.1073/Pnas.1500722112  0.38
2015 Aird KM, Worth AJ, Snyder NW, Lee JV, Sivanand S, Liu Q, Blair IA, Wellen KE, Zhang R. ATM couples replication stress and metabolic reprogramming during cellular senescence. Cell Reports. 11: 893-901. PMID 25937285 DOI: 10.1016/J.Celrep.2015.04.014  0.355
2015 Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nature Medicine. 21: 231-8. PMID 25686104 DOI: 10.1038/Nm.3799  0.389
2015 Aird KM, Zhang R. Nucleotide metabolism, oncogene-induced senescence and cancer. Cancer Letters. 356: 204-10. PMID 24486217 DOI: 10.1016/J.Canlet.2014.01.017  0.478
2015 Kaur A, Marchbank K, Dang V, O'Connell M, Webster M, Appleton J, Cheng P, Valiga A, Morissette R, McDonnell N, Ferrucci L, Kossenkov A, Meeth K, Bosenberg M, Tang H, ... ... Aird K, et al. Abstract A04: Aging microenvironment modulates melanoma invasion and metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-A04  0.328
2014 Aird KM, Zhang R. Metabolic alterations accompanying oncogene-induced senescence. Molecular & Cellular Oncology. 1: e963481. PMID 27308349 DOI: 10.4161/23723548.2014.963481  0.407
2014 Aird KM, Li H, Xin F, Konstantinopoulos PA, Zhang R. Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer. Cell Cycle (Georgetown, Tex.). 13: 199-207. PMID 24200970 DOI: 10.4161/Cc.26953  0.493
2013 Tu Z, Aird KM, Zhang R. Chromatin remodeling, BRCA1, SAHF and cellular senescence. Cell Cycle (Georgetown, Tex.). 12: 1653-4. PMID 23673322 DOI: 10.4161/Cc.24986  0.421
2013 Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence. Cell Reports. 3: 1252-65. PMID 23562156 DOI: 10.1016/J.Celrep.2013.03.004  0.439
2013 Aird KM, Zhang R. Detection of senescence-associated heterochromatin foci (SAHF). Methods in Molecular Biology (Clifton, N.J.). 965: 185-96. PMID 23296659 DOI: 10.1007/978-1-62703-239-1_12  0.407
2012 Tu Z, Aird KM, Zhang R. RAS, cellular senescence and transformation: the BRCA1 DNA repair pathway at the crossroads. Small Gtpases. 3: 163-7. PMID 22751483 DOI: 10.4161/Sgtp.19884  0.374
2012 Allensworth JL, Aird KM, Aldrich AJ, Batinic-Haberle I, Devi GR. XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells. Molecular Cancer Therapeutics. 11: 1518-27. PMID 22508521 DOI: 10.1158/1535-7163.Mct-11-0787  0.675
2012 Morse MA, Hobeika A, Serra D, Aird K, McKinney M, Aldrich A, Clay T, Mourich D, Lyerly HK, Iversen PL, Devi GR. Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function. Cancer Gene Therapy. 19: 30-7. PMID 21997230 DOI: 10.1038/Cgt.2011.63  0.603
2012 Aird KM, Allensworth JL, Batinic-Haberle I, Lyerly HK, Dewhirst MW, Devi GR. ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells. Breast Cancer Research and Treatment. 132: 109-19. PMID 21559822 DOI: 10.1007/S10549-011-1568-1  0.665
2011 Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence. Developmental Cell. 21: 1077-91. PMID 22137763 DOI: 10.1016/J.Devcel.2011.10.010  0.343
2011 Ye X, Fels D, Tovmasyan A, Aird KM, Dedeugd C, Allensworth JL, Kos I, Park W, Spasojevic I, Devi GR, Dewhirst MW, Leong KW, Batinic-Haberle I. Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate. Free Radical Research. 45: 1289-306. PMID 21859376 DOI: 10.3109/10715762.2011.616199  0.596
2011 Thomas ZI, Gibson W, Sexton JZ, Aird KM, Ingram SM, Aldrich A, Lyerly HK, Devi GR, Williams KP. Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration. British Journal of Cancer. 104: 1575-86. PMID 21505458 DOI: 10.1038/Bjc.2011.133  0.631
2010 Aird KM, Ghanayem RB, Peplinski S, Lyerly HK, Devi GR. X-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor. Molecular Cancer Therapeutics. 9: 1432-42. PMID 20406946 DOI: 10.1158/1535-7163.Mct-10-0160  0.664
2010 Thomas ZI, Sexton JZ, Gibson W, Aird KM, Aldrich A, Devi GR, Williams KP. Abstract B67: Establishment of a high-content assay to assess the affects of gene silencing on inflammatory breast cancer cell motility Cancer Epidemiology, Biomarkers & Prevention. 19. DOI: 10.1158/1055-9965.Disp-10-B67  0.664
2010 Allensworth J, Aird K, Murray M, Devi G. Abstract P1-04-01: X-Linked Inhibitor of Apoptosis Protein (XIAP) Regulates TRAIL-Induced Apoptosis in Inflammatory Breast Cancer Cells Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P1-04-01  0.526
2009 Iversen PL, Aird KM, Wu R, Morse MM, Devi GR. Cellular uptake of neutral phosphorodiamidate morpholino oligomers. Current Pharmaceutical Biotechnology. 10: 579-88. PMID 19619124 DOI: 10.2174/138920109789069279  0.634
2008 Aird KM, Ding X, Baras A, Wei J, Morse MA, Clay T, Lyerly HK, Devi GR. Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression Molecular Cancer Therapeutics. 7: 38-47. PMID 18202008 DOI: 10.1158/1535-7163.Mct-07-0370  0.671
2005 Kesavan AK, Mendez SE, Hatem CL, Lopez-Molina J, Aird K, Pitt ML, Dannenberg AM, Manabe YC. Effects of dexamethasone and transient malnutrition on rabbits infected with aerosolized Mycobacterium tuberculosis CDC1551. Infection and Immunity. 73: 7056-60. PMID 16177392 DOI: 10.1128/Iai.73.10.7056-7060.2005  0.301
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