| Year |
Citation |
Score |
| 2023 |
Bohmer MJ, Wang J, Istvan ES, Luth MR, Collins JE, Huttlin EL, Wang L, Mittal N, Hao M, Kwiatkowski NP, Gygi SP, Chakrabarti R, Deng X, Goldberg DE, Winzeler EA, et al. Human Polo-like Kinase Inhibitors as Antiplasmodials. Acs Infectious Diseases. PMID 36919909 DOI: 10.1021/acsinfecdis.3c00025 |
0.477 |
|
| 2022 |
Bhuiyan MIH, Fischer S, Patel SM, Oft H, Zhang T, Foley LM, Zhang J, Hitchens TK, Molyneaux BJ, Deng X, Sun D. Efficacy of novel SPAK inhibitor ZT-1a derivatives (1c, 1d, 1g & 1h) on improving post-stroke neurological outcome and brain lesion in mice. Neurochemistry International. 105441. PMID 36375633 DOI: 10.1016/j.neuint.2022.105441 |
0.398 |
|
| 2022 |
Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, ... ... Deng X, et al. The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK. Nature Metabolism. PMID 36217034 DOI: 10.1038/s42255-022-00640-7 |
0.698 |
|
| 2022 |
Wang J, Liu R, Hasan MN, Fischer S, Chen Y, Como M, Fiesler VM, Bhuiyan MIH, Dong S, Li E, Kahle KT, Zhang J, Deng X, Subramanya AR, Begum G, et al. Role of SPAK-NKCC1 signaling cascade in the choroid plexus blood-CSF barrier damage after stroke. Journal of Neuroinflammation. 19: 91. PMID 35413993 DOI: 10.1186/s12974-022-02456-4 |
0.393 |
|
| 2022 |
Bhuiyan MIH, Young CB, Jahan I, Hasan MN, Fischer S, Meor Azlan NF, Liu M, Chattopadhyay A, Huang H, Kahle KT, Zhang J, Poloyac SM, Molyneaux BJ, Straub AC, Deng X, et al. NF-κB Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice. Stroke. STROKEAHA121038351. PMID 35272484 DOI: 10.1161/STROKEAHA.121.038351 |
0.409 |
|
| 2021 |
Lu Y, Fan Z, Zhu SJ, Huang X, Zhuang Z, Li Y, Deng Z, Gao L, Hong X, Zhang T, Li L, Sun X, Huang W, Zhang J, Liu Y, ... ... Deng X, et al. A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC. Embo Molecular Medicine. e14296. PMID 34845836 DOI: 10.15252/emmm.202114296 |
0.784 |
|
| 2020 |
Li X, Su J, Yang Y, Lian W, Deng Z, Yang Z, Chen G, Zhang B, Dong C, Liu X, Li L, Wang Z, Hu Z, Xu Q, Deng X. Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant. European Journal of Medicinal Chemistry. 207: 112755. PMID 32882611 DOI: 10.1016/J.Ejmech.2020.112755 |
0.368 |
|
| 2020 |
Deng Z, Chen G, Liu S, Li Y, Zhong J, Zhang B, Li L, Huang H, Wang Z, Xu Q, Deng X. Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma. European Journal of Medicinal Chemistry. 206: 112697. PMID 32814244 DOI: 10.1016/J.Ejmech.2020.112697 |
0.376 |
|
| 2020 |
Ferguson FM, Liu Y, Harshbarger W, Huang L, Wang J, Deng X, Capuzzi SJ, Muratov EN, Tropsha A, Muthuswamy S, Westover KD, Gray NS. Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6-benzo[]pyrimido[5,4-][1,4]diazepin-6-one Scaffold". Journal of Medicinal Chemistry. PMID 32790356 DOI: 10.1021/acs.jmedchem.0c01338 |
0.787 |
|
| 2020 |
Wang Y, Zhang L, Wei Y, Huang W, Li L, Wu AA, Dastur A, Greninger P, Bray WM, Zhang CS, Li M, Lian W, Hu Z, Wang X, Liu G, ... ... Deng X, et al. Pharmacological Targeting of Vacuolar H-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chemical Biology. PMID 32649904 DOI: 10.1016/J.Chembiol.2020.06.011 |
0.384 |
|
| 2020 |
Ferguson FM, Liu Y, Harshbarger W, Huang L, Wang J, Deng X, Capuzzi SJ, Muratov EN, Tropsha A, Muthuswamy S, Westover KD, Gray NS. Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold. Journal of Medicinal Chemistry. PMID 32530623 DOI: 10.1021/Acs.Jmedchem.0C00596 |
0.798 |
|
| 2020 |
Zhang L, Wang Y, Huang W, Wei Y, Jiang Z, Kong L, Wu AA, Hu Z, Huang H, Xu Q, Li L, Deng X. Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility. Organic Letters. PMID 32459492 DOI: 10.1021/Acs.Orglett.0C01387 |
0.375 |
|
| 2020 |
Li W, Ni H, Wu S, Han S, Chen C, Li L, Li Y, Gui F, Han J, Deng X. Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis. Febs Letters. PMID 32412649 DOI: 10.1002/1873-3468.13812 |
0.786 |
|
| 2020 |
Chen Y, He H, Jiang H, Li L, Hu Z, Huang H, Xu Q, Zhou R, Deng X. Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors. Bioorganic & Medicinal Chemistry Letters. 127021. PMID 32057583 DOI: 10.1016/J.Bmcl.2020.127021 |
0.332 |
|
| 2020 |
Zhang J, Bhuiyan MIH, Zhang T, Karimy JK, Wu Z, Fiesler VM, Zhang J, Huang H, Hasan MN, Skrzypiec AE, Mucha M, Duran D, Huang W, Pawlak R, Foley LM, ... ... Deng X, et al. Modulation of brain cation-Cl cotransport via the SPAK kinase inhibitor ZT-1a. Nature Communications. 11: 78. PMID 31911626 DOI: 10.1038/S41467-019-13851-6 |
0.554 |
|
| 2019 |
Gui F, Jiang J, He Z, Li L, Li Y, Deng Z, Lu Y, Wu X, Chen G, Su J, Song S, Zhang YM, Yun CH, Huang X, Weisberg E, ... ... Deng X, et al. A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant Btk mutation in B-cell malignancies. British Journal of Pharmacology. PMID 31364164 DOI: 10.1111/Bph.14809 |
0.794 |
|
| 2019 |
Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, Li X, Miao X, Li S, Mi X, Zhang J, Li L, Wei G, Xu ZX, Gao X, ... ... Deng X, et al. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. PMID 30712867 DOI: 10.1016/J.Cell.2019.01.002 |
0.402 |
|
| 2018 |
Tian M, Zeng T, Liu M, Han S, Lin H, Lin Q, Li L, Jiang T, Li G, Lin H, Zhang T, Kang Q, Deng X, Wang HR. A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases. The Journal of Biological Chemistry. PMID 30587574 DOI: 10.1074/Jbc.Ra118.003822 |
0.76 |
|
| 2018 |
Tusa I, Cheloni G, Poteti M, Gozzini A, DeSouza NH, Shan Y, Deng X, Gray NS, Li S, Rovida E, Dello Sbarba P. Targeting the Extracellular Signal-Regulated Kinase 5 Pathway to Suppress Human Chronic Myeloid Leukemia Stem Cells. Stem Cell Reports. PMID 30245209 DOI: 10.1016/J.Stemcr.2018.08.016 |
0.502 |
|
| 2018 |
Ning N, Yu Y, Wu M, Zhang R, Zhang T, Zhu C, Huang L, Yun CH, Benes CH, Zhang J, Deng X, Chen Q, Ren R. A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Research. PMID 30135190 DOI: 10.1158/0008-5472.Can-18-0455 |
0.362 |
|
| 2018 |
Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, et al. Structural and atropisomeric factors governing the selectivity of pyrimido-benzodiazipinones as inhibitors of kinases and bromodomains. Acs Chemical Biology. PMID 30102854 DOI: 10.2210/Pdb6Cd5/Pdb |
0.791 |
|
| 2018 |
Czarna A, Wang J, Zelencova D, Liu Y, Deng X, Choi HG, Zhang T, Zhou W, Chang JW, Kildalsen H, Seternes OM, Gray NS, Engh RA, Rothweiler U. Novel scaffolds for Dual specificity tyrosine-phosphorylation-regulated kinase (DYRK1A) inhibitors. Journal of Medicinal Chemistry. PMID 30095246 DOI: 10.1021/acs.jmedchem.7b01847 |
0.573 |
|
| 2018 |
He H, Jiang H, Chen Y, Ye J, Wang A, Wang C, Liu Q, Liang G, Deng X, Jiang W, Zhou R. Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. Nature Communications. 9: 2550. PMID 29959312 DOI: 10.1038/S41467-018-04947-6 |
0.507 |
|
| 2018 |
Huang W, Sun X, Li Y, He Z, Li L, Deng Z, Huang X, Han S, Zhang T, Zhong J, Wang Z, Xu Q, Zhang J, Deng X. Discovery and Identification of Small Molecules as Methuosis Inducers with In Vivo Antitumor Activities. Journal of Medicinal Chemistry. PMID 29878764 DOI: 10.1021/Acs.Jmedchem.8B00753 |
0.773 |
|
| 2018 |
Huang Y, Jiang H, Chen Y, Wang X, Yang Y, Tao J, Deng X, Liang G, Zhang H, Jiang W, Zhou R. Tranilast directly targets NLRP3 to treat inflammasome-driven diseases. Embo Molecular Medicine. PMID 29531021 DOI: 10.15252/Emmm.201708689 |
0.315 |
|
| 2018 |
Tusa I, Gagliardi S, Tubita A, Pandolfi S, Urso C, Borgognoni L, Wang J, Deng X, Gray NS, Stecca B, Rovida E. ERK5 is activated by oncogenic BRAF and promotes melanoma growth. Oncogene. PMID 29483645 DOI: 10.1038/S41388-018-0164-9 |
0.534 |
|
| 2018 |
Bhuiyan MIH, Huang H, Zhang T, Molyneaux BJ, Poloyac SM, Zhang J, Deng X, Sun D, Sun D. Abstract P198: WNK-SPAK-NKCC1 Cascade Activation Contributes to Worsened Brain Damage in Mice With Hypertension Co-Morbidity after Ischemic Stroke Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P198 |
0.45 |
|
| 2018 |
Ning N, Wu C, Wu M, Yu Y, Zhu C, Benes C, Zhang J, Deng X, Chen Q, Ren R. Abstract 3926: Discovering a novel microtubule inhibitor overcoming tumor multidrug resistance Cancer Research. 78: 3926-3926. DOI: 10.1158/1538-7445.Am2018-3926 |
0.348 |
|
| 2017 |
Jiang H, He H, Chen Y, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W, Deng X, Zhou R. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. The Journal of Experimental Medicine. PMID 29021150 DOI: 10.1084/Jem.20171419 |
0.561 |
|
| 2017 |
Zhang S, Chen Q, Liu Q, Li Y, Sun X, Hong L, Ji S, Liu C, Geng J, Zhang W, Lu Z, Yin ZY, Zeng Y, Lin KH, Wu Q, ... ... Deng X, et al. Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2. Cancer Cell. 31: 669-684.e7. PMID 28486106 DOI: 10.1016/J.Ccell.2017.04.004 |
0.347 |
|
| 2017 |
Jin K, Li L, Sun X, Xu Q, Song S, Shen Y, Deng X. Mycoepoxydiene suppresses HeLa cell growth by inhibiting glycolysis and the pentose phosphate pathway. Applied Microbiology and Biotechnology. PMID 28224194 DOI: 10.1007/S00253-017-8187-7 |
0.347 |
|
| 2016 |
Beelontally R, Wilkie GS, Lau B, Goodmaker CJ, Ho CM, Swanson CM, Deng X, Wang J, Gray NS, Davison AJ, Strang BL. Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins. Antiviral Research. PMID 27956134 DOI: 10.1016/J.Antiviral.2016.12.006 |
0.496 |
|
| 2016 |
Zhang J, Deng X, Kahle KT. Leveraging unique structural characteristics of WNK kinases to achieve therapeutic inhibition. Science Signaling. 9: pe3. PMID 27811182 DOI: 10.1126/Scisignal.Aaj2227 |
0.555 |
|
| 2016 |
Ferguson FM, Ni J, Zhang T, Tesar B, Sim T, Kim ND, Deng X, Brown JR, Zhao JJ, Gray NS. Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors. Acs Medicinal Chemistry Letters. 7: 908-912. PMID 27774127 DOI: 10.1021/Acsmedchemlett.6B00209 |
0.74 |
|
| 2016 |
Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, ... ... Deng X, et al. Targeting BRK-positive breast cancers with small molecule kinase inhibitors. Cancer Research. PMID 27758886 DOI: 10.1158/0008-5472.Can-16-1038 |
0.763 |
|
| 2016 |
Huang X, Huang W, Li L, Sun X, Song S, Xu Q, Zhang L, Wei BG, Deng X. Structure Determinants of Lagunamide A for Anticancer Activity and Its Molecular Mechanism of Mitochondrial Apoptosis. Molecular Pharmaceutics. PMID 27715057 DOI: 10.1021/Acs.Molpharmaceut.6B00564 |
0.644 |
|
| 2016 |
Fan F, He Z, Kong LL, Chen Q, Yuan Q, Zhang S, Ye J, Liu H, Sun X, Geng J, Yuan L, Hong L, Xiao C, Zhang W, Sun X, ... ... Deng X, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Science Translational Medicine. 8: 352ra108. PMID 27535619 DOI: 10.1126/Scitranslmed.Aaf2304 |
0.735 |
|
| 2016 |
Iorio F, Knijnenburg TA, Vis DJ, Bignell GR, Menden MP, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Cokelaer T, Greninger P, van Dyk E, Chang H, de Silva H, ... ... Deng X, et al. A Landscape of Pharmacogenomic Interactions in Cancer. Cell. PMID 27397505 DOI: 10.1016/J.Cell.2016.06.017 |
0.582 |
|
| 2016 |
Guo JC, Deng XM, Wu J, Xun YH, Huang XX, Wang WW, Shi WZ. [Correlation between Constitution of Yin Deficiency Syndrome and Polymorphism of HLA-DQA1/Treatment Response of Peg-IFNalpha Therapy in HBeAg Positive Chronic Hepatitis B Patients]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 36: 539-43. PMID 27386643 |
0.55 |
|
| 2016 |
Wang MG, Huang XX, Yao D, An Q, Deng XQ. Effect of glucocorticoid combined with gamma globulin in treatment of children with myasthenia gravis and its effects on immune globulin and complement of children. European Review For Medical and Pharmacological Sciences. 20: 2404-8. PMID 27338067 |
0.536 |
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| 2016 |
Hwang SY, Deng X, Byun S, Lee C, Lee SJ, Suh H, Zhang J, Kang Q, Zhang T, Westover KD, Mandinova A, Lee SW. Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling. Cell Reports. PMID 27320923 DOI: 10.1016/J.Celrep.2016.05.071 |
0.574 |
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| 2016 |
Yuan ZX, Chen HB, Li SJ, Huang XW, Mo YH, Luo YN, He SN, Deng XF, Lu GD, Jiang YM. The influence of manganese treatment on the distribution of metal elements in rats and the protection by sodium para-amino salicylic acid. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 36: 84-9. PMID 27259357 DOI: 10.1016/j.jtemb.2016.04.005 |
0.539 |
|
| 2016 |
Xie J, Lu X, Wu X, Lin X, Zhang C, Huang X, Chang Z, Wang X, Wen C, Tang X, Shi M, Zhan Q, Chen H, Deng X, Peng C, et al. Capture-based next-generation sequencing reveals multiple actionable mutations in cancer patients failed in traditional testing. Molecular Genetics & Genomic Medicine. 4: 262-72. PMID 27247954 DOI: 10.1002/mgg3.201 |
0.597 |
|
| 2016 |
Tu Z, He D, Deng X, Xiong M, Huang X, Li X, Hao L, Ding Q, Zhang Q. An eight-long non-coding RNA signature as a candidate prognostic biomarker for lung cancer. Oncology Reports. PMID 27222340 DOI: 10.3892/or.2016.4817 |
0.563 |
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| 2016 |
Huang X, Xiong M, Jin Y, Deng C, Xu H, An C, Hao L, Yang X, Deng X, Tu Z, Li X, Xiao R, Zhang Q. Evidence that high-migration drug-surviving MOLT4 leukemia cells exhibit cancer stem cell-like properties. International Journal of Oncology. PMID 27210806 DOI: 10.3892/ijo.2016.3526 |
0.586 |
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| 2016 |
Chen Y, Jiang J, Zhao M, Luo X, Liang Z, Zhen Y, Fu Q, Deng X, Lin X, Li L, Luo R, Liu Z, Fang W. microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway. Oncotarget. PMID 27191497 DOI: 10.18632/oncotarget.9320 |
0.302 |
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| 2016 |
Wang YY, Wang MG, Yao D, Huang XX, Zhang T, Deng XQ. Comparison of impact on seizure frequency and epileptiform discharges of children with epilepsy from topiramate and phenobarbital. European Review For Medical and Pharmacological Sciences. 20: 993-997. PMID 27010160 |
0.524 |
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| 2016 |
Huang X, Huang Q, Dun Z, Huang W, Wu S, Liang J, Deng X, Zhang Y. Nontyphoidal Salmonella Infection, Guangdong Province, China, 2012(1). Emerging Infectious Diseases. 22: 726-729. PMID 26982074 DOI: 10.3201/eid2204.151372 |
0.563 |
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| 2016 |
Liu R, Hu D, Deng X, Zhao J, Wang W, Dai W, Zhou W, Huang X, Li M, Yang S. Shannon entropy method of small-scale self-focusing assessment in high-power laser systems. Optics Express. 24: 2293-8. PMID 26906805 |
0.544 |
|
| 2016 |
Fan X, Zhang X, Shen J, Zhao H, Yu X, Chen Y, Zhuang Z, Deng X, Feng H, Wang Y, Peng L. Decreased TUSC3 Promotes Pancreatic Cancer Proliferation, Invasion and Metastasis. Plos One. 11: e0149028. PMID 26871953 DOI: 10.1371/journal.pone.0149028 |
0.554 |
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| 2015 |
Jiang Y, Huang F, Wu F, Wu H, Huang X, Deng X. [Simultaneous determination of 16 flavonoids in the ginkgo dietary supplement tea by high performance liquid chromatography-tandem mass spectrometry]. SE Pu = Chinese Journal of Chromatography / Zhongguo Hua Xue Hui. 33: 1032-9. PMID 26930959 |
0.545 |
|
| 2015 |
Huang X, Jia H, Zhou W, Zhang F, Guo H, Deng X. Experimental demonstration of polarization smoothing in a convergent beam. Applied Optics. 54: 9786-9790. PMID 26836538 DOI: 10.1364/AO.54.009786 |
0.543 |
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| 2015 |
Maxson JE, Abel ML, Wang J, Deng X, Reckel S, Luty SB, Sun H, Gorenstein J, Hughes SB, Bottomly D, Wilmot B, McWeeney SK, Radich J, Hantschel O, Middleton RE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis. Cancer Research. PMID 26677978 DOI: 10.1158/0008-5472.Can-15-0817 |
0.504 |
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| 2015 |
Fan N, Luo Y, Xu K, Zhang M, Ke X, Huang X, Ding Y, Wang D, Ning Y, Deng X, He H. Relationship of serum levels of TNF-α, IL-6 and IL-18 and schizophrenia-like symptoms in chronic ketamine abusers. Schizophrenia Research. PMID 26589393 DOI: 10.1016/j.schres.2015.11.006 |
0.534 |
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| 2015 |
Wang Y, Qi S, Zhan Y, Zhang N, Wu AA, Gui F, Guo K, Yang Y, Cao S, Hu Z, Zheng Z, Song S, Xu Q, Shen Y, Deng X. Aspertetranones A-D, Putative Meroterpenoids from the Marine Algal-Associated Fungus Aspergillus sp. ZL0-1b14. Journal of Natural Products. PMID 26378981 DOI: 10.1021/Acs.Jnatprod.5B00487 |
0.706 |
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| 2015 |
Xia H, Huang X, Guo Y, Hu P, He G, Deng X, Xu H, Yang Z, Deng H. Identification of a Novel MYO15A Mutation in a Chinese Family with Autosomal Recessive Nonsyndromic Hearing Loss. Plos One. 10: e0136306. PMID 26308726 DOI: 10.1371/journal.pone.0136306 |
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| 2015 |
Lan Z, Hu C, Huang Y, Chen L, Ma C, Mei Z, Lin Q, Huang X, Deng X. Safety assessment of saponins extract in Dolichos falcatus Klein: Subchronic study in Sprague-Dawley rats. Journal of Ethnopharmacology. JEPD1500718. PMID 26297637 DOI: 10.1016/j.jep.2015.08.016 |
0.552 |
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| 2015 |
Moccia M, Liu Q, Guida T, Federico G, Brescia A, Zhao Z, Choi HG, Deng X, Tan L, Wang J, Billaud M, Gray NS, Carlomagno F, Santoro M. Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase. Plos One. 10: e0128364. PMID 26046350 DOI: 10.1371/Journal.Pone.0128364 |
0.645 |
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| 2015 |
Zhu L, Bu Q, Xu X, Paik I, Huang X, Hoecker U, Deng XW, Huq E. CUL4 forms an E3 ligase with COP1 and SPA to promote light-induced degradation of PIF1. Nature Communications. 6: 7245. PMID 26037329 DOI: 10.1038/Ncomms8245 |
0.568 |
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| 2015 |
Huang X, Deng X, Xu H, Wu S, Yuan L, Yang Z, Yang Y, Deng H. Identification of a Novel Mutation in the COL2A1 Gene in a Chinese Family with Spondyloepiphyseal Dysplasia Congenita. Plos One. 10: e0127529. PMID 26030151 DOI: 10.1371/journal.pone.0127529 |
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| 2015 |
Ma CB, Zhu ZT, Wang HX, Huang X, Zhang X, Qi X, Zhang HL, Zhu Y, Deng X, Peng Y, Han Y, Zhang H. A general solid-state synthesis of chemically-doped fluorescent graphene quantum dots for bioimaging and optoelectronic applications. Nanoscale. 7: 10162-9. PMID 25985855 DOI: 10.1039/C5Nr01757B |
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| 2015 |
Deng X, Huang X, Wu D. Förster resonance-energy-transfer detection of 2,4,6-trinitrophenol using copper nanoclusters. Analytical and Bioanalytical Chemistry. 407: 4607-13. PMID 25893800 DOI: 10.1007/s00216-015-8657-7 |
0.552 |
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| 2015 |
Lu W, Cheng F, Jiang J, Zhang C, Deng X, Xu Z, Zou S, Shen X, Tang Y, Huang J. FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach. Scientific Reports. 5: 8114. PMID 25631039 DOI: 10.1038/srep08114 |
0.317 |
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| 2015 |
Gu J, Lei Y, Huang Y, Zhao Y, Li J, Huang T, Zhang J, Wang J, Deng X, Chen Z, Korteweg C, Deng R, Yan M, Xu Q, Dong S, et al. Fab fragment glycosylated IgG may play a central role in placental immune evasion. Human Reproduction (Oxford, England). 30: 380-91. PMID 25505012 DOI: 10.1093/humrep/deu323 |
0.488 |
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| 2015 |
Yao L, Huang L, He Z, Zhou C, Li G, Deng X. Phosphate enhances uptake of As species in garland chrysanthemum (C. coronarium) applied with chicken manure bearing roxarsone and its metabolites. Environmental Science and Pollution Research International. 22: 4654-9. PMID 25328095 DOI: 10.1007/s11356-014-3711-0 |
0.614 |
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| 2015 |
Rovida E, Di Maira G, Tusa I, Cannito S, Paternostro C, Navari N, Vivoli E, Deng X, Gray NS, Esparís-Ogando A, David E, Pandiella A, Dello Sbarba P, Parola M, Marra F. The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma. Gut. 64: 1454-65. PMID 25183205 DOI: 10.1136/Gutjnl-2014-306761 |
0.459 |
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| 2015 |
Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, et al. Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). Journal of Medicinal Chemistry. 58: 183-96. PMID 25075558 DOI: 10.1021/Jm500480K |
0.67 |
|
| 2015 |
Lin P, Yi Y, Lu M, Wang M, Yang Y, Lu Y, Song S, Zheng Z, Deng X, Zhang L. Heat shock protein 90 inhibitor mycoepoxydiene modulates kinase signaling in cervical cancer cells and inhibits in-vivo tumor growth. Anti-Cancer Drugs. 26: 25-34. PMID 25014191 DOI: 10.1097/Cad.0000000000000135 |
0.376 |
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| 2014 |
Li W, Duan H, Chen F, Wang Z, Huang X, Deng X, Liu Y. Identification of quantitative trait loci controlling high Calcium response in Arabidopsis thaliana. Plos One. 9: e112511. PMID 25401959 DOI: 10.1371/journal.pone.0112511 |
0.554 |
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| 2014 |
Umapathy G, El Wakil A, Witek B, Chesler L, Danielson L, Deng X, Gray NS, Johansson M, Kvarnbrink S, Ruuth K, Schönherr C, Palmer RH, Hallberg B. The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma. Science Signaling. 7: ra102. PMID 25351247 DOI: 10.1126/Scisignal.2005470 |
0.526 |
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| 2014 |
Guo K, Fang T, Wang J, Wu AA, Wang Y, Jiang J, Wu X, Song S, Su W, Xu Q, Deng X. Two new spirooxindole alkaloids from rhizosphere strain Streptomyces sp. xzqh-9. Bioorganic & Medicinal Chemistry Letters. 24: 4995-8. PMID 25278238 DOI: 10.1016/J.Bmcl.2014.09.026 |
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Kim SH, Kim H, Seo KI, Kim SH, Chung S, Huang X, Yang P, Deng XW, Lee JH. DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated cellular responses in Arabidopsis. Plant Molecular Biology. 86: 571-83. PMID 25193399 DOI: 10.1007/s11103-014-0247-0 |
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Sun JC, Huang XL, Deng XR, Lv XF, Lu JL, Chen YH, Bi YF, Wang WQ, Xu M, Ning G. Elevated resting heart rate is associated with dyslipidemia in middle-aged and elderly Chinese. Biomedical and Environmental Sciences : Bes. 27: 601-5. PMID 25189606 DOI: 10.3967/bes2014.092 |
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Cao Q, Wang Y, Chen F, Xia Y, Lou J, Zhang X, Yang N, Sun X, Zhang Q, Zhuo C, Huang X, Deng X, Yang CG, Ye Y, Zhao J, et al. A novel signal transduction pathway that modulates rhl quorum sensing and bacterial virulence in Pseudomonas aeruginosa. Plos Pathogens. 10: e1004340. PMID 25166864 DOI: 10.1371/journal.ppat.1004340 |
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Wang L, Li J, Zhou Q, Yang G, Ding XL, Li X, Cai CX, Zhang Z, Wei HY, Lu TH, Deng XW, Huang XH. Rare earth elements activate endocytosis in plant cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 12936-41. PMID 25114214 DOI: 10.1073/pnas.1413376111 |
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Huang X, Ouyang X, Deng XW. Beyond repression of photomorphogenesis: role switching of COP/DET/FUS in light signaling. Current Opinion in Plant Biology. 21: 96-103. PMID 25061897 DOI: 10.1016/j.pbi.2014.07.003 |
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Ouyang X, Huang X, Jin X, Chen Z, Yang P, Ge H, Li S, Deng XW. Coordinated photomorphogenic UV-B signaling network captured by mathematical modeling. Proceedings of the National Academy of Sciences of the United States of America. 111: 11539-44. PMID 25049395 DOI: 10.1073/pnas.1412050111 |
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Deng X, Zhao X, Lan Z, Jiang J, Yin W, Chen L. Anti-tumor effects of flavonoids from the ethnic medicine Docynia delavayi (Franch.) Schneid. and its possible mechanism Journal of Medicinal Food. 17: 787-794. PMID 24940817 DOI: 10.1089/jmf.2013.2886 |
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Xu X, Paik I, Zhu L, Bu Q, Huang X, Deng XW, Huq E. PHYTOCHROME INTERACTING FACTOR1 Enhances the E3 Ligase Activity of CONSTITUTIVE PHOTOMORPHOGENIC1 to Synergistically Repress Photomorphogenesis in Arabidopsis. The Plant Cell. 26: 1992-2006. PMID 24858936 DOI: 10.1105/Tpc.114.125591 |
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Xu D, Lin F, Jiang Y, Huang X, Li J, Ling J, Hettiarachchi C, Tellgren-Roth C, Holm M, Deng XW. The RING-Finger E3 Ubiquitin Ligase COP1 SUPPRESSOR1 Negatively Regulates COP1 Abundance in Maintaining COP1 Homeostasis in Dark-Grown Arabidopsis Seedlings. The Plant Cell. 26: 1981-1991. PMID 24838976 DOI: 10.1105/tpc.114.124024 |
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Huang X, Yang P, Ouyang X, Chen L, Deng XW. Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. Plos Genetics. 10: e1004218. PMID 24651064 DOI: 10.1371/journal.pgen.1004218 |
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Huang L, Yao L, He Z, Zhou C, Li G, Yang B, Deng X. Roxarsone and its metabolites in chicken manure significantly enhance the uptake of As species by vegetables. Chemosphere. 100: 57-62. PMID 24461427 DOI: 10.1016/j.chemosphere.2013.12.074 |
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Banerjee S, Buhrlage SJ, Huang HT, Deng X, Zhou W, Wang J, Traynor R, Prescott AR, Alessi DR, Gray NS. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. The Biochemical Journal. 457: 215-25. PMID 24171924 DOI: 10.1042/Bj20131152 |
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Maxson JE, Melissa AL, Wang J, Deng X, Luty SB, Sun H, Gorenstein J, Middleton R, Gray NS, Druker BJ, Tyner JW. Development and Repurposing of Small-Molecule Kinase Inhibitors to Target Novel Leukemogenic TNK2 Mutations Blood. 124: 435-435. DOI: 10.1182/Blood.V124.21.435.435 |
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Rovida E, Maira GD, Cannito S, Tusa I, Paternostro C, Deng X, Sbarba PD, Gray NS, Parola M, Marra F. 786: The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma European Journal of Cancer. 50. DOI: 10.1016/S0959-8049(14)50691-0 |
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Deng XR, Liu ZX, Liu F, Pan L, Yu HP, Jiang JP, Zhang JJ, Liu L, Yu J. Holotransferrin enhances selective anticancer activity of artemisinin against human hepatocellular carcinoma cells. Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 33: 862-5. PMID 24337849 DOI: 10.1007/s11596-013-1212-x |
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Huang X, Deng XW. Organization of protein complexes under photomorphogenic UV-B in Arabidopsis. Plant Signaling & Behavior. 8: e27206. PMID 24304604 DOI: 10.4161/psb.27206 |
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Wu D, Deng X, Huang X, Wang K, Liu Q. Low-cost preparation of photoluminescent carbon nanodots and application as peroxidase mimetics in colorimetric detection of H2O2 and glucose. Journal of Nanoscience and Nanotechnology. 13: 6611-6. PMID 24245121 DOI: 10.1166/JNN.2013.7556 |
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Deng X, Elkins JM, Zhang J, Yang Q, Erazo T, Gomez N, Choi HG, Wang J, Dzamko N, Lee JD, Sim T, Kim N, Alessi DR, Lizcano JM, Knapp S, et al. Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones. European Journal of Medicinal Chemistry. 70: 758-67. PMID 24239623 DOI: 10.1016/J.Ejmech.2013.10.052 |
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Wu H, Xiao Y, Zhang S, Ji S, Wei L, Fan F, Geng J, Tian J, Sun X, Qin F, Jin C, Lin J, Yin ZY, Zhang T, Luo L, ... ... Deng X, et al. The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense. Cell Reports. 3: 1663-77. PMID 23684612 DOI: 10.1016/J.Celrep.2013.04.020 |
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Elkins JM, Wang J, Deng X, Pattison MJ, Arthur JS, Erazo T, Gomez N, Lizcano JM, Gray NS, Knapp S. X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor. Journal of Medicinal Chemistry. 56: 4413-21. PMID 23656407 DOI: 10.1021/Jm4000837 |
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Yao L, Huang L, He Z, Zhou C, Li G, Yang B, Deng X. External inorganic N source enhances the uptake of As species in garland chrysanthemum (C. coronarium) amended with chicken manure bearing roxarsone and its metabolites. Journal of Hazardous Materials. 254: 270-6. PMID 23632040 DOI: 10.1016/j.jhazmat.2013.03.048 |
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Yang Q, Liao L, Deng X, Chen R, Gray NS, Yates JR, Lee JD. BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction. Oncogene. 32: 3156-64. PMID 22869143 DOI: 10.1038/Onc.2012.332 |
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Deng X, Choi HG, Buhrlage SJ, Gray NS. Leucine-rich repeat kinase 2 inhibitors: a patent review (2006 - 2011). Expert Opinion On Therapeutic Patents. 22: 1415-26. PMID 23126385 DOI: 10.1517/13543776.2012.729041 |
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Li L, Gu W, Du J, Reid B, Deng X, Liu Z, Zong Z, Wang H, Yao B, Yang C, Yan J, Zeng L, Chalmers L, Zhao M, Jiang J. Electric fields guide migration of epidermal stem cells and promote skin wound healing. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 20: 840-51. PMID 23082865 DOI: 10.1111/j.1524-475X.2012.00829.x |
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Choi HG, Zhang J, Deng X, Hatcher JM, Patricelli MP, Zhao Z, Alessi DR, Gray NS. Brain Penetrant LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 3: 658-662. PMID 23066449 DOI: 10.1021/Ml300123A |
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Reith AD, Bamborough P, Jandu K, Andreotti D, Mensah L, Dossang P, Choi HG, Deng X, Zhang J, Alessi DR, Gray NS. GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor. Bioorganic & Medicinal Chemistry Letters. 22: 5625-9. PMID 22863203 DOI: 10.1016/J.Bmcl.2012.06.104 |
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Deng X, Zhou W, Weisberg E, Wang J, Zhang J, Sasaki T, Nelson E, Griffin JD, Jänne PA, Gray NS. An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kit. Bioorganic & Medicinal Chemistry Letters. 22: 4579-84. PMID 22727638 DOI: 10.1016/J.Bmcl.2012.05.107 |
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Deng X, S Gray N. Pyrazolopyridines as inhibitors of the kinase LRRK2: a patent evaluation (WO2011141756). Expert Opinion On Therapeutic Patents. 22: 709-13. PMID 22607035 DOI: 10.1517/13543776.2012.691968 |
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Luo DM, Deng XY, Zhuo SM, Tan SW, Zhuang ZF, Jin Y. [Nonlinear spectral imaging of DNA specimens derived from tumor cells based on second harmonic generation]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 32: 800-4. PMID 22582656 |
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Yang DL, Yao J, Mei CS, Tong XH, Zeng LJ, Li Q, Xiao LT, Sun TP, Li J, Deng XW, Lee CM, Thomashow MF, Yang Y, He Z, He SY. Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 109: E1192-200. PMID 22529386 DOI: 10.1073/Pnas.1201616109 |
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Hellwig S, Miduturu CV, Kanda S, Zhang J, Filippakopoulos P, Salah E, Deng X, Choi HG, Zhou W, Hur W, Knapp S, Gray NS, Smithgall TE. Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Chemistry & Biology. 19: 529-40. PMID 22520759 DOI: 10.1016/J.Chembiol.2012.01.020 |
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Garnett MJ, Edelman EJ, Heidorn SJ, Greenman CD, Dastur A, Lau KW, Greninger P, Thompson IR, Luo X, Soares J, Liu Q, Iorio F, Surdez D, Chen L, Milano RJ, ... ... Deng X, et al. Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature. 483: 570-5. PMID 22460902 DOI: 10.1038/Nature11005 |
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Zhang J, Deng X, Choi HG, Alessi DR, Gray NS. Characterization of TAE684 as a potent LRRK2 kinase inhibitor. Bioorganic & Medicinal Chemistry Letters. 22: 1864-9. PMID 22335897 DOI: 10.1016/J.Bmcl.2012.01.084 |
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Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N. Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen. Acs Chemical Biology. 7: 185-96. PMID 21992004 DOI: 10.1021/Cb200305U |
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Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discovery. 1: 78-89. PMID 22328973 DOI: 10.1158/2159-8274.Cd-11-0005 |
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Miduturu CV, Deng X, Kwiatkowski N, Yang W, Brault L, Filippakopoulos P, Chung E, Yang Q, Schwaller J, Knapp S, King RW, Lee JD, Herrgard S, Zarrinkar P, Gray NS. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors. Chemistry & Biology. 18: 868-79. PMID 21802008 DOI: 10.1016/J.Chembiol.2011.05.010 |
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Deng X, Wang J, Zhang J, Sim T, Kim ND, Sasaki T, Luther W, George RE, Jänne PA, Gray NS. Discovery of 3,5-Diamino-1,2,4-triazole Ureas as Potent Anaplastic Lymphoma Kinase Inhibitors. Acs Medicinal Chemistry Letters. 2: 379-384. PMID 21572589 DOI: 10.1021/Ml200002A |
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Deng X, Yang Q, Kwiatkowski N, Sim T, McDermott U, Settleman JE, Lee JD, Gray NS. Discovery of a benzo[e]pyrimido-[5,4-b][1,4]diazepin-6(11H)-one as a Potent and Selective Inhibitor of Big MAP Kinase 1. Acs Medicinal Chemistry Letters. 2: 195-200. PMID 21412406 DOI: 10.1021/Ml100304B |
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Deng X, Dzamko N, Prescott A, Davies P, Liu Q, Yang Q, Lee JD, Patricelli MP, Nomanbhoy TK, Alessi DR, Gray NS. Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2. Nature Chemical Biology. 7: 203-5. PMID 21378983 DOI: 10.1038/Nchembio.538 |
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Zhou R, Deng X, Zheng J, Sheng Q, Sun X, Tang Y. Stereoselective Synthesis of 1‐Aminocyclopropanecarboxylic Acid Derivatives via Ylide Cyclopropanation of Dehydroamino Acid Derivatives Chinese Journal of Chemistry. 29: 995-1000. DOI: 10.1002/Cjoc.201190202 |
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Yang Q, Deng X, Lu B, Cameron M, Fearns C, Patricelli MP, Yates JR, Gray NS, Lee JD. Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein. Cancer Cell. 18: 258-67. PMID 20832753 DOI: 10.1016/J.Ccr.2010.08.008 |
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Deng X, Okram B, Ding Q, Zhang J, Choi Y, Adrián FJ, Wojciechowski A, Zhang G, Che J, Bursulaya B, Cowan-Jacob SW, Rummel G, Sim T, Gray NS. Expanding the diversity of allosteric bcr-abl inhibitors. Journal of Medicinal Chemistry. 53: 6934-46. PMID 20828158 DOI: 10.1021/Jm100555F |
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Duan J, Zhang Y, Han S, Chen Y, Li B, Liao M, Chen W, Deng X, Zhao J, Huang B. Synthesis and in vitro/in vivo anti-cancer evaluation of curcumin-loaded chitosan/poly(butyl cyanoacrylate) nanoparticles. International Journal of Pharmaceutics. 400: 211-20. PMID 20813175 DOI: 10.1016/j.ijpharm.2010.08.033 |
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Deng X, Nagle A, Wu T, Sakata T, Henson K, Chen Z, Kuhen K, Plouffe D, Winzeler E, Adrian F, Tuntland T, Chang J, Simerson S, Howard S, Ek J, et al. Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials. Bioorganic & Medicinal Chemistry Letters. 20: 4027-31. PMID 20610151 DOI: 10.1016/J.Bmcl.2010.05.095 |
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Zhai YF, Su Q, Wu WJ, He ZT, Zhang ZY, An JS, Dong J, Deng X, Han CG, Yu JL, Li DW, Chen XL, An D. [Fast discrimination of varieties of transgene wheat based on biomimetic pattern recognition and near infrared spectra]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 30: 924-8. PMID 20545132 DOI: 10.3964/j.issn.1000-0593(2010)04-0924-05 |
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Deng X, Lim SM, Zhang J, Gray NS. Broad spectrum alkynyl inhibitors of T315I Bcr-Abl. Bioorganic & Medicinal Chemistry Letters. 20: 4196-200. PMID 20541934 DOI: 10.1016/J.Bmcl.2010.05.043 |
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Weisberg E, Deng X, Choi HG, Barrett R, Adamia S, Ray A, Moreno D, Kung AL, Gray N, Griffin JD. Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML. Leukemia. 24: 1375-8. PMID 20508612 DOI: 10.1038/Leu.2010.107 |
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Zhu BH, Zhou R, Zheng JC, Deng XM, Sun XL, Shen Q, Tang Y. Highly selective ylide-initiated Michael addition/cyclization reaction for synthesis of cyclohexadiene epoxide and vinylcyclopropane derivatives. The Journal of Organic Chemistry. 75: 3454-7. PMID 20387850 DOI: 10.1021/Jo100306Z |
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Zhang J, Adrián FJ, Jahnke W, Cowan-Jacob SW, Li AG, Iacob RE, Sim T, Powers J, Dierks C, Sun F, Guo GR, Ding Q, Okram B, Choi Y, Wojciechowski A, ... Deng X, et al. Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature. 463: 501-6. PMID 20072125 DOI: 10.1038/Nature08675 |
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Wu T, Nagle A, Sakata T, Henson K, Borboa R, Chen Z, Kuhen K, Plouffe D, Winzeler E, Adrian F, Tuntland T, Chang J, Simerson S, Howard S, Ek J, ... ... Deng X, et al. Cell-based optimization of novel benzamides as potential antimalarial leads. Bioorganic & Medicinal Chemistry Letters. 19: 6970-4. PMID 19879133 DOI: 10.1016/J.Bmcl.2009.10.050 |
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| 2009 |
Choi Y, Seeliger MA, Panjarian SB, Kim H, Deng X, Sim T, Couch B, Koleske AJ, Smithgall TE, Gray NS. N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor. The Journal of Biological Chemistry. 284: 29005-14. PMID 19679652 DOI: 10.1074/Jbc.M109.026633 |
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Qi ZY, Deng XW, Huang SM, Zhang L, He ZC, Li XA, Kwan I, Lerch M, Cutajar D, Metcalfe P, Rosenfeld A. In vivo verification of superficial dose for head and neck treatments using intensity-modulated techniques. Medical Physics. 36: 59-70. PMID 19235374 |
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Zhang J, Gray NS, Sim T, Choi Y, Deng X, Adrián F, Li A, Sun F, Liu Y, Okram B, Warmuth M, Iacob R, Engen J, Powers J, Azam M, et al. Abstract B165: Abl kinase myristate‐site inhibitor, mechanism and application Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B165 |
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Zhu CY, Deng XM, Sun XL, Zheng JC, Tang Y. Highly enantioselective synthesis of isoxazoline N-oxides. Chemical Communications (Cambridge, England). 738-40. PMID 18478708 DOI: 10.1039/B716468H |
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| 2008 |
Wang Q, Deng X, Zhu B, Ye L, Sun X, Li C, Zhu C, Shen Q, Tang Y. Tandem Michael addition/ylide epoxidation for the synthesis of highly functionalized cyclohexadiene epoxide derivatives. Journal of the American Chemical Society. 130: 5408-5409. PMID 18376828 DOI: 10.1021/Ja800747M |
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| 2008 |
Zhu C, Sun X, Deng X, Zheng J, Tang Y. Synthesis of isoxazoline N-oxides and its application in the formal synthesis of dehydroclausenamide Tetrahedron. 64: 5583-5589. DOI: 10.1016/J.Tet.2008.03.075 |
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| 2006 |
Deng XM, Cai P, Ye S, Sun XL, Liao WW, Li K, Tang Y, Wu YD, Dai LX. Enantioselective synthesis of vinylcyclopropanes and vinylepoxides mediated by camphor-derived sulfur ylides: rationale of enantioselectivity, scope, and limitation. Journal of the American Chemical Society. 128: 9730-40. PMID 16866528 DOI: 10.1021/Ja056751O |
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| 2006 |
Deng X, Wang X, Liu H, Zhuang Z, Guo Z. Simulation study of second-harmonic microscopic imaging signals through tissue-like turbid media. Journal of Biomedical Optics. 11: 024013. PMID 16674203 DOI: 10.1117/1.2191055 |
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| 2005 |
Deng X, Sun Y, Han S. [General principles of urban ecological land classification and planning]. Ying Yong Sheng Tai Xue Bao = the Journal of Applied Ecology / Zhongguo Sheng Tai Xue Xue Hui, Zhongguo Ke Xue Yuan Shenyang Ying Yong Sheng Tai Yan Jiu Suo Zhu Ban. 16: 2003-6. PMID 16422530 |
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Jiang H, Deng X, Sun X, Tang Y, Dai LX. Highly stereoselective synthesis of trisubstituted vinylcyclopropane derivatives via arsonium ylides. The Journal of Organic Chemistry. 70: 10202-5. PMID 16292874 DOI: 10.1021/Jo051782N |
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Zhang S, Chen C, Li L, Meng L, Singh J, Jiang N, Deng XW, He ZH, Lemaux PG. Evolutionary expansion, gene structure, and expression of the rice wall-associated kinase gene family. Plant Physiology. 139: 1107-24. PMID 16286450 DOI: 10.1104/Pp.105.069005 |
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| 2005 |
Deng XM, Sun XL, Tang Y. Highly regioselective rearrangement of 2-substituted vinylepoxides catalyzed by gallium(III) triflate. The Journal of Organic Chemistry. 70: 6537-40. PMID 16050727 DOI: 10.1021/Jo050810Z |
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Deng X, Li QB, Lu YH, He N, Jiang J. Genetic engineering of E-coli SE5000 and its potential for Ni2+ bioremediation Process Biochemistry. 40: 425-430. DOI: 10.1016/J.Procbio.2004.01.019 |
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Huang SF, Yang ZL, Deng XH, Miao XY, Zhuang ZG, Li YG. [Correlative study on the expression of ER mRNA and presenilin 2 in the pancreatic carcinoma tissues]. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 29: 438-40. PMID 16134599 |
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| 2004 |
Liao WW, Deng XM, Tang Y. A facile reaction of imines with telluronium allylide. Highly stereoselective synthesis of vinylaziridines. Chemical Communications (Cambridge, England). 1516-7. PMID 15216358 DOI: 10.1039/B400464G |
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Wang Z, Li X, Shi S, Qi D, He Z, Xu W, Deng X. [A comparison study on the species diversity between the gap and non-gap in Jinyun Mountain]. Ying Yong Sheng Tai Xue Bao = the Journal of Applied Ecology / Zhongguo Sheng Tai Xue Xue Hui, Zhongguo Ke Xue Yuan Shenyang Ying Yong Sheng Tai Yan Jiu Suo Zhu Ban. 14: 7-10. PMID 12722429 |
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| 2003 |
Li K, Deng X, Tang Y. A facile tetrahydrothiophene-catalyzed ylide route to vinyloxiranes. Chemical Communications. 2074-2075. DOI: 10.1039/B304443B |
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| 2001 |
Ma SC, He ZD, Deng XL, But PP, Ooi VE, Xu HX, Lee SH, Lee SF. In vitro evaluation of secoiridoid glucosides from the fruits of Ligustrum lucidum as antiviral agents. Chemical & Pharmaceutical Bulletin. 49: 1471-3. PMID 11724241 DOI: 10.1248/Cpb.49.1471 |
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| 2015 |
Ran Q, Xiang Y, Liu Y, Xiang L, Li F, Deng X, Xiao Y, Chen L, Chen L, Li Z. Eryptosis Indices as a Novel Predictive Parameter for Biocompatibility of Fe3O4 Magnetic Nanoparticles on Erythrocytes. Scientific Reports. 5: 16209. PMID 26537855 DOI: 10.1038/srep16209 |
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| 2011 |
Yin K, Deng X, Mo ZC, Zhao GJ, Jiang J, Cui LB, Tan CZ, Wen GB, Fu Y, Tang CK. Tristetraprolin-dependent post-transcriptional regulation of inflammatory cytokine mRNA expression by apolipoprotein A-I: role of ATP-binding membrane cassette transporter A1 and signal transducer and activator of transcription 3. The Journal of Biological Chemistry. 286: 13834-45. PMID 21339300 DOI: 10.1074/Jbc.M110.202275 |
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| 2018 |
Liu M, Zeng T, Zhang X, Liu C, Wu Z, Yao L, Xie C, Xia H, Lin Q, Xie L, Zhou D, Deng X, Chan HL, Zhao TJ, Wang HR. ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage. Nature Communications. 9: 4139. PMID 30297842 DOI: 10.1038/S41467-018-06556-9 |
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| 2015 |
Wu H, Wei L, Fan F, Ji S, Zhang S, Geng J, Hong L, Fan X, Chen Q, Tian J, Jiang M, Sun X, Jin C, Yin ZY, Liu Q, ... ... Deng X, et al. Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis. Nature Communications. 6: 6239. PMID 25695629 DOI: 10.1038/Ncomms7239 |
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| 2013 |
Wang Y, Deng X, Liu J, Tang H, Jiang J. Surface enhanced Raman scattering based sensitive detection of histone demethylase activity using a formaldehyde-selective reactive probe. Chemical Communications (Cambridge, England). 49: 8489-91. PMID 23938472 DOI: 10.1039/c3cc44243h |
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| 2022 |
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