| Year |
Citation |
Score |
| 2023 |
Barnard TR, Landry BN, Wang AB, Sagan SM. Zika virus NS3 and NS5 proteins determine strain-dependent differences in dsRNA accumulation in a host cell type-dependent manner. The Journal of General Virology. 104. PMID 37289497 DOI: 10.1099/jgv.0.001855 |
0.465 |
|
| 2023 |
Rheault M, Cousineau SE, Fox DR, Abram QH, Sagan SM. Elucidating the distinct contributions of miR-122 in the HCV life cycle reveals insights into virion assembly. Nucleic Acids Research. PMID 36807979 DOI: 10.1093/nar/gkad094 |
0.493 |
|
| 2022 |
Sagan SM, Weber SC. Let's phase it: viruses are master architects of biomolecular condensates. Trends in Biochemical Sciences. PMID 36272892 DOI: 10.1016/j.tibs.2022.09.008 |
0.335 |
|
| 2022 |
Barnard TR, Wang AB, Sagan SM. A highly sensitive strand-specific multiplex RT-qPCR assay for quantitation of Zika virus replication. Journal of Virological Methods. 307: 114556. PMID 35654259 DOI: 10.1016/j.jviromet.2022.114556 |
0.384 |
|
| 2022 |
Cousineau SE, Rheault M, Sagan SM. Poly(rC)-Binding Protein 1 Limits Hepatitis C Virus Virion Assembly and Secretion. Viruses. 14. PMID 35215884 DOI: 10.3390/v14020291 |
0.572 |
|
| 2021 |
Chahal J, Gebert LFR, Camargo C, MacRae IJ, Sagan SM. miR-122-based therapies select for three distinct resistance mechanisms based on alterations in RNA structure. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34385308 DOI: 10.1073/pnas.2103671118 |
0.438 |
|
| 2021 |
Barnard TR, Abram QH, Lin QF, Wang AB, Sagan SM. Molecular Determinants of Flavivirus Virion Assembly. Trends in Biochemical Sciences. PMID 33423940 DOI: 10.1016/j.tibs.2020.12.007 |
0.309 |
|
| 2020 |
Cousineau SE, Erman A, Liu L, Saeed S, Fradette L, Feld JJ, Grebely J, MacParland SA, Shoukry NH, Sebastiani G, Sagan SM. The 8 Canadian Symposium on Hepatitis C virus: "Improving diagnosis and linkage to care". Canadian Liver Journal. 3: 3-14. PMID 35992037 DOI: 10.3138/canlivj.2019-0032 |
0.394 |
|
| 2020 |
Chahal J, Gebert LF, Gan HH, Gunsalus KC, MacRae IJ, Sagan SM. A Moonlighting microRNA: Mechanism(s) of miR-122-Mediated Viral RNA Accumulation Proceedings. 50: 131. DOI: 10.3390/proceedings2020050131 |
0.428 |
|
| 2019 |
van Vlymen JM, Magnus J, Jaeger M, Breton S, Taylor NG, Phelan R, Sagan SM. Hepatitis C Contamination of Medication Vials Accessed with Sterile Needles and Syringes. Anesthesiology. PMID 31166244 DOI: 10.1097/Aln.0000000000002772 |
0.406 |
|
| 2019 |
Chahal J, Gebert LFR, Gan HH, Camacho E, Gunsalus KC, MacRae IJ, Sagan SM. miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5' terminus. Nucleic Acids Research. PMID 30941417 DOI: 10.1093/Nar/Gkz194 |
0.487 |
|
| 2019 |
Bernier A, Sagan SM. Beyond sites 1 and 2, miR-122 target sites in the HCV genome have negligible contributions to HCV RNA accumulation in cell culture. The Journal of General Virology. PMID 30652963 DOI: 10.1099/Jgv.0.001217 |
0.544 |
|
| 2018 |
Cheng ML, Abdel-Hakeem MS, Cousineau SE, Grebely J, Marshall AD, Saeed S, Sagan SM, Shoukry NH, Feld JJ, MacParland SA. The 7th Canadian Symposium on Hepatitis C Virus: "Toward Elimination of HCV: How to Get There". Canadian Liver Journal. 1: 139-152. PMID 35991324 DOI: 10.3138/canlivj.2018-0018 |
0.424 |
|
| 2018 |
Khan S, Bernier A, Dapp D, Fortier E, Krajden M, King A, Grebely J, Sagan SM, Cooper CL, Crawley AM. 6th Canadian Symposium on Hepatitis C Virus: Delivering a cure for hepatitis C infection-What are the remaining gaps? Canadian Liver Journal. 1: 94-105. PMID 35990718 DOI: 10.3138/canlivj.1.2.008 |
0.406 |
|
| 2018 |
Barnard TR, Rajah MM, Sagan SM. Contemporary Zika Virus Isolates Induce More dsRNA and Produce More Negative-Strand Intermediate in Human Astrocytoma Cells. Viruses. 10. PMID 30572570 DOI: 10.3390/V10120728 |
0.4 |
|
| 2018 |
Canuti M, Williams CV, Sagan SM, Oude Munnink BB, Gadi S, Verhoeven JTP, Kellam P, Cotten M, Lang AS, Junge RE, Cullen JM, van der Hoek L. Virus discovery reveals frequent infection by diverse novel members of the Flaviviridae in wild lemurs. Archives of Virology. PMID 30460488 DOI: 10.1007/S00705-018-4099-9 |
0.359 |
|
| 2018 |
Juźwik CA, Drake S, Lécuyer MA, Johnson RM, Morquette B, Zhang Y, Charabati M, Sagan SM, Bar-Or A, Prat A, Fournier AE. Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis. Scientific Reports. 8: 13437. PMID 30194392 DOI: 10.1038/S41598-018-31542-Y |
0.431 |
|
| 2018 |
Bernier A, Sagan SM. The Diverse Roles of microRNAs at the Host⁻Virus Interface. Viruses. 10. PMID 30126238 DOI: 10.3390/V10080440 |
0.381 |
|
| 2018 |
Amador-Cañizares Y, Bernier A, Wilson JA, Sagan SM. miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11. Nucleic Acids Research. PMID 29672716 DOI: 10.1093/Nar/Gky273 |
0.511 |
|
| 2018 |
Alpuche-Lazcano SP, McCullogh CR, Del Corpo O, Rance E, Scarborough RJ, Mouland AJ, Sagan SM, Teixeira MM, Gatignol A. Higher Cytopathic Effects of a Zika Virus Brazilian Isolate from Bahia Compared to a Canadian-Imported Thai Strain. Viruses. 10. PMID 29382068 DOI: 10.3390/V10020053 |
0.414 |
|
| 2018 |
Cheng ML, Abdel-Hakeem MS, Cousineau SE, Grebely J, Marshall AD, Saeed S, Sagan SM, Shoukry NH, Feld JJ, MacParland SA. The 7th Canadian Symposium on Hepatitis C Virus: “Toward Elimination of HCV: How to Get There” Canadian Liver Journal. 1: 139-152. DOI: 10.3138/CANLIVJ.2018-0018 |
0.435 |
|
| 2018 |
Khan S, Bernier A, Dapp D, Fortier E, Krajden M, King A, Grebely J, Sagan SM, Cooper CL, Crawley AM. 6th Canadian Symposium on Hepatitis C Virus: Delivering a cure for hepatitis C infection—What are the remaining gaps? Canadian Liver Journal. 1: 94-105. DOI: 10.3138/CANLIVJ.1.2.008 |
0.305 |
|
| 2018 |
Bernier A, Amador Y, Sagan S, Wilson JA. A186 INVESTIGATION OF THE PROTECTIVE ROLE OF MIR-122 AGAINST CELLULAR SENSORS OF RNA AT THE 5’ TERMINUS OF HEPATITIS C VIRUS GENOME Journal of the Canadian Association of Gastroenterology. 1: 322-323. DOI: 10.1093/jcag/gwy008.187 |
0.337 |
|
| 2017 |
Barnard TR, Rajah MM, Sagan SM. Zika virus infection: induction, restriction and evasion of host interferon responses Future Virology. 12: 627-630. DOI: 10.2217/Fvl-2017-0099 |
0.365 |
|
| 2016 |
van Buuren N, Fradette L, Grebely J, King A, Krajden M, MacParland SA, Marshall A, Saeed S, Wilson J, Klein MB, Sagan SM. The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet-Remaining Challenges in Hepatitis C. Canadian Journal of Gastroenterology & Hepatology. 2016: 7603526. PMID 27843889 DOI: 10.1155/2016/7603526 |
0.5 |
|
| 2016 |
Rajah MM, Pardy RD, Condotta SA, Richer MJ, Sagan SM. Zika Virus: Emergence, Phylogenetics, Challenges, and Opportunities. Acs Infectious Diseases. 2: 763-772. PMID 27704772 DOI: 10.1021/Acsinfecdis.6B00161 |
0.321 |
|
| 2016 |
Sarnow P, Sagan SM. Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122. Annual Review of Virology. PMID 27578438 DOI: 10.1146/Annurev-Virology-110615-042409 |
0.513 |
|
| 2016 |
Sagan SM, Dupont B, Grebely J, Krajden M, MacParland SA, Raven JF, Saeed S, Feld JJ, Tyrrell DL, Wilson JA. Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan. Canadian Journal of Gastroenterology & Hepatology. 2016: 5743521. PMID 27446849 DOI: 10.1155/2016/5743521 |
0.491 |
|
| 2016 |
Kulkarni AS, Damha MJ, Schinazi RF, Mo H, Doehle B, Sagan SM, Götte M. A complex network of interactions between S282 and G283 of HCV NS5B and the template strand affect susceptibility to Sofosbuvir and Ribavirin. Antimicrobial Agents and Chemotherapy. PMID 26824949 DOI: 10.1128/Aac.02436-15 |
0.462 |
|
| 2015 |
Sagan SM, Chahal J, Sarnow P. cis-Acting RNA elements in the hepatitis C virus RNA genome. Virus Research. 206: 90-8. PMID 25576644 DOI: 10.1016/J.Virusres.2014.12.029 |
0.608 |
|
| 2015 |
Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Dissecting noncoding and pathogen RNA-protein interactomes. Rna (New York, N.Y.). 21: 135-43. PMID 25411354 DOI: 10.1261/Rna.047803.114 |
0.506 |
|
| 2014 |
MacParland SA, Bilodeau M, Grebely J, Bruneau J, Cooper C, Klein M, Sagan S, Choucha N, Balfour L, Bialystok F, Krajden M, Raven J, Roberts E, Russell R, Houghton M, et al. The 3rd Canadian Symposium on Hepatitis C Virus: expanding care in the interferon-free era. Canadian Journal of Gastroenterology & Hepatology. 28: 481-7. PMID 25314353 DOI: 10.1155/2014/704919 |
0.511 |
|
| 2014 |
Wilson JA, Sagan SM. Hepatitis C virus and human miR-122: insights from the bench to the clinic. Current Opinion in Virology. 7: 11-8. PMID 24721497 DOI: 10.1016/J.Coviro.2014.03.005 |
0.517 |
|
| 2013 |
Grebely J, Bilodeau M, Feld JJ, Bruneau J, Fischer B, Raven JF, Roberts E, Choucha N, Myers RP, Sagan SM, Wilson JA, Bialystok F, Tyrrell DL, Houghton M, Krajden M, et al. The Second Canadian Symposium on hepatitis C virus: a call to action. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 27: 627-32. PMID 24199209 DOI: 10.1155/2013/242405 |
0.497 |
|
| 2013 |
Sagan SM, Sarnow P. Molecular biology. RNAi, Antiviral after all. Science (New York, N.Y.). 342: 207-8. PMID 24115433 DOI: 10.1126/Science.1245475 |
0.464 |
|
| 2013 |
Cox EM, Sagan SM, Mortimer SA, Doudna JA, Sarnow P. Enhancement of hepatitis C viral RNA abundance by precursor miR-122 molecules. Rna (New York, N.Y.). 19: 1825-32. PMID 24106328 DOI: 10.1261/Rna.040865.113 |
0.39 |
|
| 2013 |
Sagan SM, Sarnow P, Wilson JA. Modulation of GB virus B RNA abundance by microRNA-122: dependence on and escape from microRNA-122 restriction. Journal of Virology. 87: 7338-47. PMID 23616647 DOI: 10.1128/Jvi.00378-13 |
0.542 |
|
| 2013 |
Nasheri N, Pezacki JP, Sagan SM. Design and screening of siRNAs against highly structured RNA targets. Methods in Molecular Biology (Clifton, N.J.). 942: 69-86. PMID 23027046 DOI: 10.1007/978-1-62703-119-6_4 |
0.622 |
|
| 2012 |
Machlin ES, Sarnow P, Sagan SM. Combating hepatitis C virus by targeting microRNA-122 using locked nucleic acids. Current Gene Therapy. 12: 301-6. PMID 22856605 DOI: 10.2174/156652312802083558 |
0.384 |
|
| 2011 |
Machlin ES, Sarnow P, Sagan SM. Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 3193-8. PMID 21220300 DOI: 10.1073/Pnas.1012464108 |
0.47 |
|
| 2010 |
Sagan SM, Nasheri N, Luebbert C, Pezacki JP. The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility. Chemistry & Biology. 17: 515-27. PMID 20534349 DOI: 10.1016/J.Chembiol.2010.04.011 |
0.74 |
|
| 2010 |
Sagan SM, Sarnow P. Plasmacytoid dendritic cells as guardians in hepatitis C virus-infected liver. Proceedings of the National Academy of Sciences of the United States of America. 107: 7625-6. PMID 20404186 DOI: 10.1073/Pnas.1002943107 |
0.513 |
|
| 2009 |
Lyn RK, Kennedy DC, Sagan SM, Blais DR, Rouleau Y, Pegoraro AF, Xie XS, Stolow A, Pezacki JP. Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism. Virology. 394: 130-42. PMID 19747705 DOI: 10.1016/J.Virol.2009.08.022 |
0.782 |
|
| 2009 |
Koukiekolo R, Jakubek ZJ, Cheng J, Sagan SM, Pezacki JP. Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: a FRET-based probe for sensing double-stranded fluorophore tagged small RNAs. Biophysical Chemistry. 143: 166-9. PMID 19491057 DOI: 10.1016/J.Bpc.2009.05.001 |
0.669 |
|
| 2009 |
Cheng J, Koukiekolo R, Kieliszkiewicz K, Sagan SM, Pezacki JP. Cysteine residues of Carnation Italian Ringspot virus p19 suppressor of RNA silencing maintain global structural integrity and stability for siRNA binding. Biochimica Et Biophysica Acta. 1794: 1197-203. PMID 19341824 DOI: 10.1016/J.Bbapap.2009.03.012 |
0.643 |
|
| 2009 |
Pezacki JP, Sagan SM, Tonary AM, Rouleau Y, Bélanger S, Supekova L, Su AI. Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus. Bmc Chemical Biology. 9: 2. PMID 19149867 DOI: 10.1186/1472-6769-9-2 |
0.762 |
|
| 2009 |
Koukiekolo R, Jakubek ZJ, Cheng J, Sagan SM, Pezacki JP. Erratum to “Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: A FRET-based probe for sensing double-stranded fluorophore tagged small RNAs” [Biophysical Chemistry 143 (2009) 166–169] Biophysical Chemistry. 145: 45. DOI: 10.1016/J.Bpc.2009.08.005 |
0.667 |
|
| 2008 |
Davis M, Sagan SM, Pezacki JP, Evans DJ, Simmonds P. Bioinformatic and physical characterizations of genome-scale ordered RNA structure in mammalian RNA viruses. Journal of Virology. 82: 11824-36. PMID 18799591 DOI: 10.1128/Jvi.01078-08 |
0.704 |
|
| 2008 |
Cheng J, Sagan SM, Jakubek ZJ, Pezacki JP. Studies of the interaction of the viral suppressor of RNA silencing protein p19 with small RNAs using fluorescence polarization. Biochemistry. 47: 8130-8. PMID 18597480 DOI: 10.1021/Bi800401Y |
0.659 |
|
| 2007 |
Cheng J, Sagan SM, Assem N, Koukiekolo R, Goto NK, Pezacki JP. Stabilized recombinant suppressors of RNA silencing: functional effects of linking monomers of Carnation Italian Ringspot virus p19. Biochimica Et Biophysica Acta. 1774: 1528-35. PMID 17976393 DOI: 10.1016/J.Bbapap.2007.09.014 |
0.655 |
|
| 2007 |
Koukiekolo R, Sagan SM, Pezacki JP. Effects of pH and salt concentration on the siRNA binding activity of the RNA silencing suppressor protein p19. Febs Letters. 581: 3051-6. PMID 17559839 DOI: 10.1016/J.Febslet.2007.05.064 |
0.631 |
|
| 2007 |
Sagan SM, Koukiekolo R, Rodgers E, Goto NK, Pezacki JP. Inhibition of siRNA binding to a p19 viral suppressor of RNA silencing by cysteine alkylation. Angewandte Chemie (International Ed. in English). 46: 2005-9. PMID 17286327 DOI: 10.1002/Anie.200603284 |
0.663 |
|
| 2006 |
Sagan SM, Rouleau Y, Leggiadro C, Supekova L, Schultz PG, Su AI, Pezacki JP. The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 67-79. PMID 16462891 DOI: 10.1139/O05-149 |
0.766 |
|
| 2006 |
Rakic B, Sagan SM, Noestheden M, Bélanger S, Nan X, Evans CL, Xie XS, Pezacki JP. Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication. Chemistry & Biology. 13: 23-30. PMID 16426968 DOI: 10.1016/J.Chembiol.2005.10.006 |
0.79 |
|
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