Kwok-Wai Lo - Publications

Affiliations: 
The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Molecular Biology, Oncology

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Year Citation  Score
2024 Wu M, Hau PM, Li L, Tsang CM, Yang Y, Taghbalout A, Chung GT, Hui SY, Tang WC, Jillette N, Zhu JJ, Lee HHY, Kong EL, Chan MSA, Chan JYK, ... ... Lo KW, et al. Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers. Nature Communications. 15: 3729. PMID 38702330 DOI: 10.1038/s41467-024-48031-8  0.315
2024 Chai AWY, Yee SM, Lee HM, Abdul Aziz N, Yee PS, Marzuki M, Wong KW, Chiang AKS, Chow LK, Dai W, Liu TF, Tan LP, Khoo ASB, Lo KW, Lim PV, et al. Establishment and characterization of an Epstein-Barr virus-positive cell line from a non-keratinizing differentiated primary nasopharyngeal carcinoma. Cancer Research Communications. PMID 38358347 DOI: 10.1158/2767-9764.CRC-23-0341  0.305
2022 Chen L, Chiang YC, Chan LS, Chau WY, Lung ML, Kahn M, Lo KW, Mak NK, Lung HL. The CBP/β-Catenin Antagonist, ICG-001, Inhibits Tumor Metastasis via Blocking of the miR-134/ITGB1 Axis-Mediated Cell Adhesion in Nasopharyngeal Carcinoma. Cancers. 14. PMID 35804897 DOI: 10.3390/cancers14133125  0.301
2021 Tan KE, Ng WL, Marinov GK, Yu KH, Tan LP, Liau ES, Goh SY, Yeo KS, Yip KY, Lo KW, Khoo AS, Yap LF, Ea CK, Lim YY. Identification and characterization of a novel Epstein-Barr Virus-encoded circular RNA from LMP-2 Gene. Scientific Reports. 11: 14392. PMID 34257379 DOI: 10.1038/s41598-021-93781-w  0.307
2021 Bruce JP, To KF, Lui VWY, Chung GTY, Chan YY, Tsang CM, Yip KY, Ma BBY, Woo JKS, Hui EP, Mak MKF, Lee SD, Chow C, Velapasamy S, Or YYY, ... ... Lo KW, et al. Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nature Communications. 12: 4193. PMID 34234122 DOI: 10.1038/s41467-021-24348-6  0.301
2021 Chan LKY, Lau TS, Chung KY, Tam C, Cheung TH, Yim SF, Lee JHS, Leung RWT, Qin J, Or YYY, Lo KW, Kwong J. Short-Form Thymic Stromal Lymphopoietin (sfTSLP) Is the Predominant Isoform Expressed by Gynaecologic Cancers and Promotes Tumour Growth. Cancers. 13. PMID 33652749 DOI: 10.3390/cancers13050980  0.31
2020 Xue Z, Lui VWY, Li Y, Jia L, You C, Li X, Piao W, Yuan H, Khong PL, Lo KW, Cheung LWT, Lee VHF, Lee AWM, Tsao SW, Tsang CM. Therapeutic evaluation of palbociclib and its compatibility with other chemotherapies for primary and recurrent nasopharyngeal carcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 39: 262. PMID 33243298 DOI: 10.1186/s13046-020-01763-z  0.306
2020 Zhu J, Li L, Tong J, Hui C, Wong CH, Lo KW, Chan R, Ai QY, Hui EP, Chan AT, To KF, Tao Q, Ma BB. Targeting the polycomb repressive complex-2 related proteins with novel combinational strategies for nasopharyngeal carcinoma. American Journal of Cancer Research. 10: 3267-3284. PMID 33163269  0.359
2020 Chan LS, Lung HL, Ngan RK, Lee AW, Tsao SW, Lo KW, Kahn M, Lung ML, Wieser R, Mak NK. Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation. International Journal of Molecular Sciences. 21. PMID 32752071 DOI: 10.3390/Ijms21155495  0.375
2020 Chau SL, Tong JH, Chow C, Kwan JS, Lung RW, Chung LY, Tin EK, Wong SS, Cheung AH, Lau RW, Ng CS, Mok TS, Lo KW, To KF. Distinct Molecular Landscape of Epstein-Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing. Cancers. 12. PMID 32726920 DOI: 10.3390/Cancers12082065  0.397
2020 Hau PM, Lung HL, Wu M, Tsang CM, Wong KL, Mak NK, Lo KW. Targeting Epstein-Barr Virus in Nasopharyngeal Carcinoma. Frontiers in Oncology. 10: 600. PMID 32528868 DOI: 10.3389/Fonc.2020.00600  0.356
2020 Ngan HL, Poon PHY, Su YX, Chan JYK, Lo KW, Yeung CK, Liu Y, Wong E, Li H, Lau CW, Piao W, Lui VWY. Erlotinib sensitivity of p.D321N mutation in head and neck squamous cell carcinoma. Npj Genomic Medicine. 5: 17. PMID 32351709 DOI: 10.1038/S41525-020-0124-5  0.348
2020 Ngan HL, Poon PHY, Su Y, Chan JYK, Lo K, Yeung CK, Liu Y, Wong E, Li H, Lau CW, Piao W, Lui VWY. Abstract 1792: MAPK1 p.D321N mutation confers sensitive to erlotinib in head and neck squamous cell carcinoma (HNSCC) Cancer Research. 80: 1792-1792. DOI: 10.1158/1538-7445.Am2020-1792  0.38
2019 Jiang L, Lung HL, Huang T, Lan R, Zha S, Chan LS, Thor W, Tsoi TH, Chau HF, Boreström C, Cobb SL, Tsao SW, Bian ZX, Law GL, Wong WT, ... ... Lo KW, et al. Reactivation of Epstein-Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn-chelating function. Proceedings of the National Academy of Sciences of the United States of America. PMID 31822610 DOI: 10.1073/Pnas.1915372116  0.395
2019 Yiu SPT, Hui KF, Münz C, Lo KW, Tsao SW, Kao RYT, Yang D, Chiang AKS. Autophagy-Dependent Reactivation of Epstein-Barr Virus Lytic Cycle and Combinatorial Effects of Autophagy-Dependent and Independent Lytic Inducers in Nasopharyngeal Carcinoma. Cancers. 11. PMID 31769432 DOI: 10.3390/Cancers11121871  0.374
2019 Tsang CM, Yan Lui VW, Bruce JP, Pugh TJ, Lo KW. Translational Genomics of Nasopharyngeal Cancer. Seminars in Cancer Biology. PMID 31521748 DOI: 10.1016/j.semcancer.2019.09.006  0.314
2018 Siu EH, Chan AW, Chong CC, Chan SL, Lo KW, Cheung ST. Treatment of advanced hepatocellular carcinoma: immunotherapy from checkpoint blockade to potential of cellular treatment. Translational Gastroenterology and Hepatology. 3: 89. PMID 30603725 DOI: 10.21037/Tgh.2018.10.16  0.352
2018 Chan LS, Man OY, Kwok HH, Chen L, Chan KC, Lung HL, Ngan RK, Wong RN, Lo KW, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK. The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis. International Journal of Oncology. PMID 30569106 DOI: 10.3892/Ijo.2018.4664  0.394
2018 Lin W, Yip YL, Jia L, Deng W, Zheng H, Dai W, Ko JMY, Lo KW, Chung GTY, Yip KY, Lee SD, Kwan JS, Zhang J, Liu T, Chan JY, et al. Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma. Nature Communications. 9: 4663. PMID 30405107 DOI: 10.1038/S41467-018-06889-5  0.324
2018 Zhang J, Zhou Y, Huang T, Wu F, Pan Y, Dong Y, Wang Y, Chan AKY, Liu L, Kwan JSH, Cheung AHK, Wong CC, Lo AKF, Cheng ASL, Yu J, ... Lo KW, et al. FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p. Oncogene. PMID 30082912 DOI: 10.1038/S41388-018-0430-X  0.31
2018 Lo AK, Lung RW, Dawson CW, Young LS, Ko CW, Yeung WW, Kang W, To KF, Lo KW. Activation of SREBP1-mediated lipogenesis by the Epstein-Barr Virus-encoded LMP1 promotes cell proliferation and progression of nasopharyngeal carcinoma. The Journal of Pathology. PMID 29968360 DOI: 10.1002/Path.5130  0.474
2018 Ngan HL, Wang L, Lo KW, Lui VWY. Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer. Cancers. 10. PMID 29933636 DOI: 10.3390/Cancers10070210  0.383
2018 Wong CH, Ma BBY, Hui CWC, Lo KW, Hui EP, Chan ATC. Preclinical evaluation of ribociclib and its synergistic effect in combination with alpelisib in non-keratinizing nasopharyngeal carcinoma. Scientific Reports. 8: 8010. PMID 29789630 DOI: 10.1038/S41598-018-26201-1  0.376
2018 Yip YL, Lin W, Deng W, Jia L, Lo KW, Busson P, Vérillaud B, Liu X, Tsang CM, Lung ML, Tsao SW. Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29769697 DOI: 10.1038/S41374-018-0034-7  0.312
2018 Lung RW, Hau P, Tong JH, Lam K, Chan AW, Yip KY, Tsao GS, Lo K, To K. Abstract 482: Epstein-Barr virus-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma Cancer Research. 78: 482-482. DOI: 10.1158/1538-7445.Am2018-482  0.398
2018 Lam K, Lung RW, Hau P, Yip KY, Tsao GS, Yu KH, Tong JH, Lo K, To K. Abstract 2462: Epstein-Barr virus-encoded microRNAs regulate the expression of BRCA1 in nasopharyngeal carcinoma Cancer Research. 78: 2462-2462. DOI: 10.1158/1538-7445.Am2018-2462  0.439
2017 Lung RW, Hau PM, Yu KH, Yip KY, Tong JH, Chak WP, Chan AW, Lam KH, Lo AK, Tin EK, Chau SL, Pang JC, Kwan JS, Busson P, Young LS, ... ... Lo KW, et al. EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma. The Journal of Pathology. PMID 29230817 DOI: 10.1002/Path.5018  0.412
2017 Lui VWY, To KF, Lo KW. Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays. Cancer. PMID 29165785 DOI: 10.1002/Cncr.31131  0.369
2017 Tsao SW, Tsang CM, Lo KW. Epstein-Barr virus infection and nasopharyngeal carcinoma. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28893937 DOI: 10.1098/rstb.2016.0270  0.307
2017 Lo AK, Dawson CW, Young LS, Lo KW. The role of Metabolic Reprogramming in γ-Herpesvirus-associated Oncogenesis. International Journal of Cancer. PMID 28542909 DOI: 10.1002/Ijc.30795  0.319
2017 Lee HM, Lo KW, Wei W, Tsao SW, Chung GT, Ibrahim MH, Dawson CW, Murray PG, Paterson IC, Yap LF. Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. The Journal of Pathology. PMID 28240350 DOI: 10.1002/Path.4879  0.414
2017 Li YY, Chung GT, Lui VW, To KF, Ma BB, Chow C, Woo JK, Yip KY, Seo J, Hui EP, Mak MK, Rusan M, Chau NG, Or YY, Law MH, ... ... Lo KW, et al. Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations. Nature Communications. 8: 14121. PMID 28098136 DOI: 10.1038/Ncomms14121  0.383
2016 Chak WP, Lung RW, Tong JH, Chan SY, Lun SW, Tsao SW, Lo KW, To KF. Down-regulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma. Molecular Carcinogenesis. PMID 27597634 DOI: 10.1002/Mc.22569  0.42
2016 Cheung CC, Lun SW, Chung GT, Chow C, Lo C, Choy KW, Lo KW. MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma. Bmc Cancer. 16: 495. PMID 27431799 DOI: 10.1186/S12885-016-2525-5  0.424
2016 Xu M, Cheung CC, Chow C, Lun SW, Cheung ST, Lo KW. Overexpression of PIN1 Enhances Cancer Growth and Aggressiveness with Cyclin D1 Induction in EBV-Associated Nasopharyngeal Carcinoma. Plos One. 11: e0156833. PMID 27258148 DOI: 10.1371/Journal.Pone.0156833  0.431
2016 Tsang DP, Wu WK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang W, Li MS, Lau SS, Li X, Lee SD, Yang Y, ... ... Lo KW, et al. Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates Nuclear Factor-κB in hepatocellular carcinoma. The Journal of Pathology. PMID 26800240 DOI: 10.1002/Path.4688  0.404
2016 Lung RW, Hau TP, Chak W, Tong JH, Yu KH, Tsao S, Yip KY, To K, Lo K. Abstract 1118: The role of Epstein-Barr virus-encoded miRNAs in ATM regulating DNA damage response in nasopharyngeal carcinoma Cancer Research. 76: 1118-1118. DOI: 10.1158/1538-7445.Am2016-1118  0.41
2015 Lo AK, Dawson CW, Young LS, Ko CW, Hau PM, Lo KW. Activation of the FGFR1 signalling pathway by the Epstein-Barr Virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells. The Journal of Pathology. PMID 26096068 DOI: 10.1002/Path.4575  0.417
2015 Chan KC, Chan LS, Ip JC, Lo C, Yip TT, Ngan RK, Wong RN, Lo KW, Ng WT, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK. Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin. Scientific Reports. 5: 9979. PMID 25897700 DOI: 10.1038/Srep09979  0.332
2015 Tsao SW, Tsang CM, To KF, Lo KW. The role of Epstein-Barr virus in epithelial malignancies. The Journal of Pathology. 235: 323-33. PMID 25251730 DOI: 10.1002/Path.4448  0.441
2015 Yip TTC, Ngan RKC, Ng W, Chan LTC, Tai WCS, Cheng W, Ma VWS, Lo K, Li Y, Yang MBH, Wong ECH, Ma BBY, Mak N, Tsao GSW, Li-Lung M. Abstract 1734: Preclinical study of HSP-90 inhibitor drug, AUY922 showed good efficacy in treatment of nasopharyngeal cancer Cancer Research. 75: 1734-1734. DOI: 10.1158/1538-7445.Am2015-1734  0.424
2014 Tso KY, Lee SD, Lo KW, Yip KY. Are special read alignment strategies necessary and cost-effective when handling sequencing reads from patient-derived tumor xenografts? Bmc Genomics. 15: 1172. PMID 25539684 DOI: 10.1186/1471-2164-15-1172  0.329
2014 Lun SW, Cheung ST, Lo KW. Cancer stem-like cells in Epstein-Barr virus-associated nasopharyngeal carcinoma. Chinese Journal of Cancer. 33: 529-38. PMID 25223912 DOI: 10.5732/Cjc.014.10081  0.41
2014 Yuen JW, Chung GT, Lun SW, Cheung CC, To KF, Lo KW. Epigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinoma. Plos One. 9: e105163. PMID 25126743 DOI: 10.1371/Journal.Pone.0105163  0.482
2014 Cheung CC, Chung GT, Lun SW, To KF, Choy KW, Lau KM, Siu SP, Guan XY, Ngan RK, Yip TT, Busson P, Tsao SW, Lo KW. miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis. Molecular Cancer. 13: 184. PMID 25098679 DOI: 10.1186/1476-4598-13-184  0.341
2014 Tsao SW, Yip YL, Tsang CM, Pang PS, Lau VM, Zhang G, Lo KW. Etiological factors of nasopharyngeal carcinoma. Oral Oncology. 50: 330-8. PMID 24630258 DOI: 10.1016/j.oraloncology.2014.02.006  0.303
2014 Gressette M, Vérillaud B, Jimenez-Pailhès AS, Lelièvre H, Lo KW, Ferrand FR, Gattolliat CH, Jacquet-Bescond A, Kraus-Berthier L, Depil S, Busson P. Treatment of nasopharyngeal carcinoma cells with the histone-deacetylase inhibitor abexinostat: cooperative effects with cis-platin and radiotherapy on patient-derived xenografts. Plos One. 9: e91325. PMID 24618637 DOI: 10.1371/Journal.Pone.0091325  0.364
2014 Lau TS, Chung TK, Cheung TH, Chan LK, Cheung LW, Yim SF, Siu NS, Lo KW, Yu MM, Kulbe H, Balkwill FR, Kwong J. Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts. The Journal of Pathology. 232: 43-56. PMID 24014111 DOI: 10.1002/Path.4258  0.36
2014 Mak CK, Chung GT, Yip KY, Tso KK, Lee S, Cheung S, Tsao S, Busson P, To K, Lo K. Abstract 3425: Whole-transcriptome analyses of EBV-associated nasopharyngeal carcinoma using next-generation transcriptome sequencing Cancer Research. 74: 3425-3425. DOI: 10.1158/1538-7445.Am2014-3425  0.48
2013 Chan KC, Ting CM, Chan PS, Lo MC, Lo KW, Curry JE, Smyth T, Lee AW, Ng WT, Tsao GS, Wong RN, Lung ML, Mak NK. A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation. Molecular Cancer. 12: 128. PMID 24156782 DOI: 10.1186/1476-4598-12-128  0.367
2013 Tso KK, Yip KY, Mak CK, Chung GT, Lee SD, Cheung ST, To KF, Lo KW. Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1. Infectious Agents and Cancer. 8: 29. PMID 23915735 DOI: 10.1186/1750-9378-8-29  0.418
2013 Chung GT, Lung RW, Hui AB, Yip KY, Woo JK, Chow C, Tong CY, Lee SD, Yuen JW, Lun SW, Tso KK, Wong N, Tsao SW, Yip TT, Busson P, ... ... Lo KW, et al. Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma. The Journal of Pathology. 231: 158-67. PMID 23878065 DOI: 10.1002/Path.4240  0.457
2013 Chung GT, Lou WP, Chow C, To KF, Choy KW, Leung AW, Tong CY, Yuen JW, Ko CW, Yip TT, Busson P, Lo KW. Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma. The Journal of Pathology. 231: 311-22. PMID 23868181 DOI: 10.1002/Path.4239  0.42
2013 Lo AK, Lo KW, Ko CW, Young LS, Dawson CW. Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells. The Journal of Pathology. 230: 336-46. PMID 23592276 DOI: 10.1002/Path.4201  0.425
2013 Lo MC, Yip TC, Ngan KC, Cheng WW, Law CK, Chan PS, Chan KC, Wong CK, Wong RN, Lo KW, Ng WT, Lee WM, Tsao SW, Kwong LW, Lung ML, et al. Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres. Cancer Letters. 335: 81-92. PMID 23403077 DOI: 10.1016/J.Canlet.2013.01.052  0.395
2013 Vérillaud B, Gressette M, Jimenez A, Lelièvre H, Lo K, Jacquet-Bescond A, Kraus-Berthier L, Depil S, Busson P. Abstract 1013: Treatment of EBV-positive nasopharyngeal carcinoma xenografts with the HDAC-inhibitor Abexinostat: synergy with cis-platinum. Cancer Research. 73: 1013-1013. DOI: 10.1158/1538-7445.Am2013-1013  0.416
2012 Lun SW, Cheung ST, Cheung PF, To KF, Woo JK, Choy KW, Chow C, Cheung CC, Chung GT, Cheng AS, Ko CW, Tsao SW, Busson P, Ng MH, Lo KW. CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma. Plos One. 7: e52426. PMID 23285037 DOI: 10.1371/Journal.Pone.0052426  0.448
2012 Lo AK, Dawson CW, Jin DY, Lo KW. The pathological roles of BART miRNAs in nasopharyngeal carcinoma. The Journal of Pathology. 227: 392-403. PMID 22431062 DOI: 10.1002/Path.4025  0.347
2012 Lo KW, Chung GT, To KF. Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches. Seminars in Cancer Biology. 22: 79-86. PMID 22245473 DOI: 10.1016/J.Semcancer.2011.12.011  0.351
2012 Man CH, Wei-Man Lun S, Wai-Ying Hui J, To KF, Choy KW, Wing-Hung Chan A, Chow C, Tin-Yun Chung G, Tsao SW, Tak-Chun Yip T, Busson P, Lo KW. Inhibition of NOTCH3 signalling significantly enhances sensitivity to cisplatin in EBV-associated nasopharyngeal carcinoma. The Journal of Pathology. 226: 471-81. PMID 22009689 DOI: 10.1002/Path.2997  0.457
2012 Cheung CC, Chung GT, Lun SW, Choy K, To K, Lo K. Abstract 2288: Genetic and epigenetic inactivation of miR-31 in EBV-associated nasopharyngeal carcinoma Cancer Research. 72: 2288-2288. DOI: 10.1158/1538-7445.Am2012-2288  0.391
2010 Chan SY, To KF, Leung SF, Yip WW, Mak MK, Chung GT, Lo KW. 14-3-3sigma expression as a prognostic marker in undifferentiated nasopharyngeal carcinoma. Oncology Reports. 24: 949-55. PMID 20811675 DOI: 10.3892/or-00000941  0.314
2010 Shi W, Alajez NM, Bastianutto C, Hui AB, Mocanu JD, Ito E, Busson P, Lo KW, Ng R, Waldron J, O'Sullivan B, Liu FF. Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer. International Journal of Cancer. Journal International Du Cancer. 126: 2036-48. PMID 19739117 DOI: 10.1002/Ijc.24880  0.392
2010 Or YY, Chung GT, To KF, Chow C, Choy KW, Tong CY, Leung AW, Hui AB, Tsao SW, Ng HK, Yip TT, Busson P, Lo KW. Identification of a novel 12p13.3 amplicon in nasopharyngeal carcinoma. The Journal of Pathology. 220: 97-107. PMID 19718711 DOI: 10.1002/Path.2609  0.31
2010 Lun SW, Man C, Hui JW, Chow C, Choy K, Kwong J, Lin H, To K, Lo K. Abstract 356: Targeting NOTCH3 signaling pathway enhances chemosensitivity in EBV-positive NPC cells Cancer Research. 70: 356-356. DOI: 10.1158/1538-7445.Am10-356  0.479
2009 Lung RW, Tong JH, Sung YM, Leung PS, Ng DC, Chau SL, Chan AW, Ng EK, Lo KW, To KF. Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22. Neoplasia (New York, N.Y.). 11: 1174-84. PMID 19881953 DOI: 10.1593/Neo.09888  0.361
2009 Kwok WK, Pang JC, Lo KW, Ng HK. Role of the RARRES1 gene in nasopharyngeal carcinoma. Cancer Genetics and Cytogenetics. 194: 58-64. PMID 19737656 DOI: 10.1016/J.Cancergencyto.2009.06.005  0.389
2009 Chan MW, Hui AB, Yip SK, Ng CF, Lo KW, Tong JH, Chan AW, Cheung HY, Wong WS, Chan PS, Lai FM, To KF. Progressive increase of genetic alteration in urinary bladder cancer by combined allelotyping analysis and comparative genomic hybridization. International Journal of Oncology. 34: 963-70. PMID 19287953 DOI: 10.3892/Ijo_00000222  0.317
2008 Alajez NM, Mocanu JD, Shi W, Chia MC, Breitbach CJ, Hui AB, Knowles S, Bell JC, Busson P, Takada K, Lo KW, O'Sullivan B, Gullane P, Liu FF. Efficacy of systemically administered mutant vesicular stomatitis virus (VSVDelta51) combined with radiation for nasopharyngeal carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4891-7. PMID 18676763 DOI: 10.1158/1078-0432.Ccr-07-4134  0.358
2008 Wang L, Shan L, Lo KW, Yin J, Zhang Y, Sun R, Zhong J. Inhibition of nasopharyngeal carcinoma growth by RTA-expressing baculovirus vectors containing oriP. The Journal of Gene Medicine. 10: 1124-33. PMID 18642396 DOI: 10.1002/Jgm.1237  0.351
2008 Chang SS, Lo YC, Chua HH, Chiu HY, Tsai SC, Chen JY, Lo KW, Tsai CH. Critical role of p53 in histone deacetylase inhibitor-induced Epstein-Barr virus Zta expression. Journal of Virology. 82: 7745-51. PMID 18495777 DOI: 10.1128/Jvi.02717-07  0.418
2007 Mocanu JD, Yip KW, Alajez NM, Shi W, Li JH, Lunt SJ, Moriyama EH, Wilson BC, Milosevic M, Lo KW, van Rooijen NV, Busson P, Bastianutto C, Liu FF. Imaging the Modulation of Adenoviral Kinetics and Biodistribution for Cancer Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 921-929. PMID 28182894 DOI: 10.1038/Mt.Sj.6300119  0.372
2007 Mocanu JD, Yip KW, Skliarenko J, Shi W, Busson P, Lo KW, Bastianutto C, Liu FF. Imaging and modulating antisense microdistribution in solid human xenograft tumor models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5935-41. PMID 17908990 DOI: 10.1158/1078-0432.Ccr-06-3085  0.334
2007 Kwong J, Chow LS, Wong AY, Hung WK, Chung GT, To KF, Chan FL, Daigo Y, Nakamura Y, Huang DP, Lo KW. Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma. Genes, Chromosomes & Cancer. 46: 171-80. PMID 17099870 DOI: 10.1002/Gcc.20398  0.49
2007 Man C, Rosa J, Lee LT, Lee VH, Chow BK, Lo KW, Doxsey S, Wu ZG, Kwong YL, Jin DY, Cheung AL, Tsao SW. Latent membrane protein 1 suppresses RASSF1A expression, disrupts microtubule structures and induces chromosomal aberrations in human epithelial cells. Oncogene. 26: 3069-80. PMID 17099724 DOI: 10.1038/Sj.Onc.1210106  0.458
2006 Shi W, Bastianutto C, Li A, Perez-Ordonez B, Ng R, Chow KY, Zhang W, Jurisica I, Lo KW, Bayley A, Kim J, O'Sullivan B, Siu L, Chen E, Liu FF. Multiple dysregulated pathways in nasopharyngeal carcinoma revealed by gene expression profiling. International Journal of Cancer. 119: 2467-75. PMID 16858677 DOI: 10.1002/Ijc.22107  0.39
2006 Kwong J, Lee JY, Wong KK, Zhou X, Wong DT, Lo KW, Welch WR, Berkowitz RS, Mok SC. Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer. Neoplasia (New York, N.Y.). 8: 268-78. PMID 16756719 DOI: 10.1593/Neo.05502  0.311
2006 Lo AK, Lo KW, Tsao SW, Wong HL, Hui JW, To KF, Hayward DS, Chui YL, Lau YL, Takada K, Huang DP. Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells. Neoplasia (New York, N.Y.). 8: 173-80. PMID 16611410 DOI: 10.1593/Neo.05625  0.306
2005 Wong HL, Wang X, Chang RCC, Jin DY, Feng H, Wang Q, Lo KW, Huang DP, Yuen PW, Takada K, Wong YC, Tsao SW. Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress Molecular Carcinogenesis. 44: 92-101. PMID 16086371 DOI: 10.1002/Mc.20133  0.384
2005 Kwong J, Lo KW, Chow LS, To KF, Choy KW, Chan FL, Mok SC, Huang DP. Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma. Neoplasia (New York, N.Y.). 7: 67-74. PMID 15720818 DOI: 10.1593/Neo.04370  0.346
2005 Kwong J, Lo KW, Chow LS, Chan FL, To KF, Huang DP. Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma. International Journal of Cancer. 113: 386-92. PMID 15455391 DOI: 10.1002/Ijc.20593  0.457
2004 Bai AH, Tong JH, To KF, Chan MW, Man EP, Lo KW, Lee JF, Sung JJ, Leung WK. Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia. International Journal of Cancer. 112: 846-53. PMID 15386372 DOI: 10.1002/Ijc.20485  0.367
2004 Lo AK, Huang DP, Lo KW, Chui YL, Li HM, Pang JC, Tsao SW. Phenotypic alterations induced by the Hong Kong-prevalent Epstein-Barr virus-encoded LMP1 variant (2117-LMP1) in nasopharyngeal epithelial cells. International Journal of Cancer. 109: 919-25. PMID 15027126 DOI: 10.1002/Ijc.20051  0.339
2004 Chow LS, Lo KW, Kwong J, To KF, Tsang KS, Lam CW, Dammann R, Huang DP. RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma. International Journal of Cancer. 109: 839-47. PMID 15027117 DOI: 10.1002/Ijc.20079  0.464
2004 Chow LS, Lo K, Kwong J, Wong AY, Huang DP. Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma Oncology Reports. 12: 781-787. DOI: 10.3892/Or.12.4.781  0.365
2003 Hui AB, Lo KW, Kwong J, Lam EC, Chan SY, Chow LS, Chan AS, Teo PM, Huang DP. Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma. Molecular Carcinogenesis. 38: 170-8. PMID 14639656 DOI: 10.1002/Mc.10156  0.445
2002 Lo KW, Huang DP. Genetic and epigenetic changes in nasopharyngeal carcinoma Seminars in Cancer Biology. 12: 451-462. PMID 12450731 DOI: 10.1016/S1044579X02000883  0.404
2002 Kung FY, Tse GM, Lo KW, Law BK, Chang AR, Chen MH. Metachronous bilateral mammary metaplastic and infiltrating duct carcinomas: a molecular study for clonality. Human Pathology. 33: 677-9. PMID 12152169 DOI: 10.1053/Hupa.2002.124906  0.375
2002 Lo KW, Tsang YS, Kwong J, To KF, Teo PM, Huang DP. Promoter hypermethylation of the EDNRB gene in nasopharyngeal carcinoma. International Journal of Cancer. 98: 651-5. PMID 11920632 DOI: 10.1002/Ijc.10271  0.427
2002 Hui AB, Lo KW, Chan SY, Kwong J, Chan AS, Huang DP. Absence of SDHD mutations in primary nasopharyngeal carcinomas. International Journal of Cancer. 97: 875-7. PMID 11857371 DOI: 10.1002/Ijc.10066  0.309
2002 Hui AB, Lo K, Teo PML, To K, Huang DP. Genome wide detection of oncogene amplifications in nasopharyngeal carcinoma by array based comparative genomic hybridization. International Journal of Oncology. 20: 467-473. DOI: 10.3892/Ijo.20.3.467  0.377
1999 Liew CT, Li HM, Lo KW, Leow CK, Chan JY, Hin LY, Lau WY, Lai PB, Lim BK, Huang J, Leung WT, Wu S, Lee JC. High frequency of p16INK4A gene alterations in hepatocellular carcinoma. Oncogene. 18: 789-95. PMID 9989830 DOI: 10.1038/Sj.Onc.1202359  0.386
1999 Ng MH, Kan A, Chung YF, Wong IH, Lo KW, Wickham NW, Lei KI, Lee JC. Combined morphological and interphase fluorescence in situ hybridization study in multiple myeloma of Chinese patients. The American Journal of Pathology. 154: 15-22. PMID 9916913 DOI: 10.1016/S0002-9440(10)65245-5  0.31
1998 Hui ABY, Cheung ST, Fong Y, Lo KW, Huang DP. Characterization of a new EBV-associated nasopharyngeal carcinoma cell line Cancer Genetics and Cytogenetics. 101: 83-88. PMID 9494607 DOI: 10.1016/S0165-4608(97)00231-8  0.402
1997 Tse JY, Wong JH, Lo KW, Poon WS, Huang DP, Ng HK. Molecular genetic analysis of the von Hippel-Lindau disease tumor suppressor gene in familial and sporadic cerebellar hemangioblastomas. American Journal of Clinical Pathology. 107: 459-66. PMID 9124215 DOI: 10.1093/Ajcp/107.4.459  0.334
1996 Cheung ST, Lo KW, Leung SF, Chan WY, Choi PH, Johnson PJ, Lee JC, Huang DP. Prevalence of LMP1 deletion variant of Epstein-Barr virus in nasopharyngeal carcinoma and gastric tumors in Hong Kong International Journal of Cancer. Journal International Du Cancer. 66: 711-712. PMID 8647637 DOI: 10.1002/(Sici)1097-0215(19960529)66:5<711::Aid-Ijc21>3.0.Co;2-5  0.369
1993 Choi PHK, Suen MWM, Huang DP, Lo K, Lee JCK. Nasopharyngeal carcinoma : genetic changes, Epstein-Barr virus infection, or both : a clinical and molecular study of 36 patients Cancer. 72: 2873-2878. PMID 8106138 DOI: 10.1002/1097-0142(19931115)72:10<2873::Aid-Cncr2820721003>3.0.Co;2-A  0.382
1991 Huang DP, Lo KW, Choi PH, Ng AY, Tsao SY, Yiu GK, Lee JC. Loss of heterozygosity on the short arm of chromosome 3 in nasopharyngeal carcinoma. Cancer Genetics and Cytogenetics. 54: 91-9. PMID 1676610 DOI: 10.1016/0165-4608(91)90035-S  0.371
Low-probability matches (unlikely to be authored by this person)
2019 Chen L, Chan LS, Lung HL, Yip TTC, Ngan RKC, Wong JWC, Lo KW, Ng WT, Lee AWM, Tsao GSW, Lung ML, Mak NK. Crucifera sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1 (WIF1) axis. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 63: 153058. PMID 31394414 DOI: 10.1016/J.Phymed.2019.153058  0.299
2021 Emanuel O, Liu J, Schartinger VH, Nei WL, Chan YY, Tsang CM, Riechelmann H, Masterson L, Haybaeck J, Oppermann U, Willems SM, Ooft ML, Wollmann G, Howard D, Vanhaesebroeck B, ... ... Lo KW, et al. SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target. Cancers. 13. PMID 34638429 DOI: 10.3390/cancers13194944  0.298
2006 Or YY, Hui AB, To KF, Lam CN, Lo KW. PIK3CA mutations in nasopharyngeal carcinoma. International Journal of Cancer. 118: 1065-7. PMID 16114017 DOI: 10.1002/Ijc.21444  0.297
2018 Jiang L, Xie C, Lung HL, Lo KW, Law GL, Mak NK, Wong KL. EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers. Theranostics. 8: 5307-5319. PMID 30555548 DOI: 10.7150/Thno.26823  0.294
2010 Koon HK, Lo KW, Leung KN, Lung ML, Chang CC, Wong RN, Leung WN, Mak NK. Photodynamic therapy-mediated modulation of inflammatory cytokine production by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Cellular & Molecular Immunology. 7: 323-6. PMID 20228836 DOI: 10.1038/Cmi.2010.4  0.292
2005 Or Y, Hui AB, Tam K, Huang DP, Lo K. Characterization of chromosome 3q and 12q amplicons in nasopharyngeal carcinoma cell lines. International Journal of Oncology. 26: 49-56. DOI: 10.3892/Ijo.26.1.49  0.29
2022 Abdul Rahman SF, Azlan A, Lo KW, Azzam G, Mohana-Kumaran N. Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells. Discover. Oncology. 13: 9. PMID 35201512 DOI: 10.1007/s12672-022-00470-9  0.289
2010 Yang EV, Webster Marketon JI, Chen M, Lo KW, Kim SJ, Glaser R. Glucocorticoids activate Epstein Barr virus lytic replication through the upregulation of immediate early BZLF1 gene expression. Brain, Behavior, and Immunity. 24: 1089-96. PMID 20466055 DOI: 10.1016/j.bbi.2010.04.013  0.285
2020 Lung RW, Tong JH, Ip LM, Lam KH, Chan AW, Chak WP, Chung LY, Yeung WW, Hau PM, Chau SL, Tsao SW, Lau KM, Lo KW, To KF. EBV-encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1. Journal of Cellular and Molecular Medicine. PMID 33074587 DOI: 10.1111/jcmm.16007  0.284
2019 Zhang J, Jia L, Liu T, Yip YL, Tang WC, Lin W, Deng W, Lo KW, You C, Lung ML, Lung HL, Cheung AL, Tsao SW, Tsang CM. mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma. Oncogene. PMID 30745576 DOI: 10.1038/S41388-019-0749-Y  0.281
2023 Zhang J, Chen B, Wang Y, Liu X, Yan H, Wong KY, Chan AK, Cheung AH, Chow C, Xu D, Wang S, Huang B, Liang L, Ke H, Wong CC, ... ... Lo KW, et al. The E2F1-HOXB9/PBX2-CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer. The Journal of Pathology. PMID 37272544 DOI: 10.1002/path.6091  0.28
2008 Zhou HY, Wan KF, Ip CK, Wong CK, Mak NK, Lo KW, Wong AS. Hepatocyte growth factor enhances proteolysis and invasiveness of human nasopharyngeal cancer cells through activation of PI3K and JNK. Febs Letters. 582: 3415-22. PMID 18789327 DOI: 10.1016/j.febslet.2008.09.004  0.278
2022 Zhang J, Chen B, Li H, Wang Y, Liu X, Wong KY, Chan WN, Chan AKY, Cheung AHK, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, ... ... Lo KW, et al. Cancer-associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2-IGF1R and Hippo-YAP1 signaling pathways. The Journal of Pathology. PMID 36373776 DOI: 10.1002/path.6033  0.278
2005 Choy KW, Lee TC, Cheung KF, Fan DS, Lo KW, Beaverson KL, Abramson DH, Lam DS, Yu CB, Pang CP. Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma. Neoplasia (New York, N.Y.). 7: 200-6. PMID 15799820 DOI: 10.1593/neo.04565  0.276
2022 Wang Y, Chen H, Liu W, Yan H, Zhang Y, Cheung AHK, Zhang J, Chen B, Liang L, Zhou Z, Wong CC, Wu WKK, Chan MWY, Cheng ASL, Ma BBY, ... ... Lo KW, et al. MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target. Theranostics. 12: 6509-6526. PMID 36185598 DOI: 10.7150/thno.75431  0.275
2020 Zhang J, Wong CC, Leung KT, Wu F, Zhou Y, Tong JHM, Chan RCK, Li H, Wang Y, Yan H, Liu L, Wu WKK, Chan MWY, Cheng ASL, Yu J, ... ... Lo KW, et al. FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential. Oncogene. PMID 32934314 DOI: 10.1038/S41388-020-01458-X  0.273
2012 Tsang CM, Yip YL, Lo KW, Deng W, To KF, Hau PM, Lau VM, Takada K, Lui VW, Lung ML, Chen H, Zeng M, Middeldorp JM, Cheung AL, Tsao SW. Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 109: E3473-82. PMID 23161911 DOI: 10.1073/Pnas.1202637109  0.271
2010 Ma BB, Lui VW, Poon FF, Wong SC, To KF, Wong E, Chen H, Lo KW, Tao Q, Chan AT, Ng MH, Cheng SH. Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response. Investigational New Drugs. 28: 326-33. PMID 19756373 DOI: 10.1007/S10637-009-9316-7  0.27
2022 Tang WC, Tsao SW, Jones GE, Liu X, Tsai MH, Delecluse HJ, Dai W, You C, Zhang J, Huang SCM, Leung MM, Liu T, Ching YP, Chen H, Lo KW, et al. Latent Membrane Protein 1 and macrophage-derived TNFα synergistically activate and mobilize invadopodia to drive invasion of nasopharyngeal carcinoma. The Journal of Pathology. PMID 36420735 DOI: 10.1002/path.6036  0.268
2003 Chan MW, Chan LW, Tang NL, Lo KW, Tong JH, Chan AW, Cheung HY, Wong WS, Chan PS, Lai FM, To KF. Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients. International Journal of Cancer. 104: 611-6. PMID 12594816 DOI: 10.1002/ijc.10971  0.267
2002 Hui AB, Lo KW, Teo PM, To KF, Huang DP. Genome wide detection of oncogene amplifications in nasopharyngeal carcinoma by array based comparative genomic hybridization International Journal of Oncology. 20: 467-473. PMID 11836556  0.266
2019 Fung SW, Fung-Yi Cheung P, Yip CW, Wing-Chi Ng L, Cheung TT, Ching-Ning Chong C, Lee C, Bo-San Lai P, Wing-Hung Chan A, Sai-Wah Tsao G, Wong CH, Chan SL, Lo KW, Cheung ST. The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemo-resistance, EMT and cancer stemness in hepatocellular carcinoma. Cancer Letters. PMID 31100412 DOI: 10.1016/j.canlet.2019.05.010  0.266
2016 Cheung PF, Yip CW, Ng LW, Lo KW, Chow C, Chan KF, Cheung TT, Cheung ST. Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line. Cancer Cell International. 16: 41. PMID 27279800 DOI: 10.1186/s12935-016-0322-5  0.265
2010 Tsang CM, Zhang G, Seto E, Takada K, Deng W, Yip YL, Man C, Hau PM, Chen H, Cao Y, Lo KW, Middeldorp JM, Cheung AL, Tsao SW. Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization. International Journal of Cancer. Journal International Du Cancer. 127: 1570-83. PMID 20091869 DOI: 10.1002/ijc.25173  0.264
2007 Lo AK, To KF, Lo KW, Lung RW, Hui JW, Liao G, Hayward SD. Modulation of LMP1 protein expression by EBV-encoded microRNAs. Proceedings of the National Academy of Sciences of the United States of America. 104: 16164-9. PMID 17911266 DOI: 10.1073/Pnas.0702896104  0.263
2020 Ngan HL, Liu Y, Fong AY, Poon PHY, Yeung CK, Chan SSM, Lau A, Piao W, Li H, Tse JSW, Lo KW, Chan SM, Su YX, Chan JYK, Lau CW, et al. MAPK pathway mutations in head and neck cancer affect immune microenvironments and ErbB3 signaling. Life Science Alliance. 3. PMID 32381551 DOI: 10.26508/lsa.201900545  0.263
2021 Lechner M, Schartinger VH, Steele CD, Nei WL, Ooft ML, Schreiber LM, Pipinikas CP, Chung GT, Chan YY, Wu F, To KF, Tsang CM, Pearce W, Morelli D, Philpott M, ... ... Lo KW, et al. Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. Nature Communications. 12: 117. PMID 33402692 DOI: 10.1038/s41467-020-20308-8  0.258
2017 Li L, Leung AK, Kwok TP, Lai YYY, Pang IK, Chung GT, Mak ACY, Poon A, Chu C, Li M, Wu JJK, Lam ET, Cao H, Lin C, Sibert J, ... ... Lo KW, et al. OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps. Genome Biology. 18: 230. PMID 29195502 DOI: 10.1186/S13059-017-1356-2  0.258
2005 Chan KC, Chan AT, Leung SF, Pang JC, Wang AY, Tong JH, To KF, Chan LY, Tam LL, Chung NY, Zhang J, Lo KW, Huang DP, Lo YM. Investigation into the origin and tumoral mass correlation of plasma Epstein-Barr virus DNA in nasopharyngeal carcinoma. Clinical Chemistry. 51: 2192-5. PMID 16244302 DOI: 10.1373/Clinchem.2005.054783  0.257
2021 Yi C, Lai SL, Tsang CM, Artemenko M, Tang MKS, Pang SW, Lo KW, Tsao SW, Wong AST. A 3D spheroid-specific role of Wnt/β-catenin and Eph-Ephrin in nasopharyngeal carcinoma cells. Journal of Cell Science. PMID 34338780 DOI: 10.1242/jcs.256461  0.257
2022 Wong KY, Cheung AH, Chen B, Chan WN, Yu J, Lo KW, Kang W, To KF. Cancer-associated fibroblasts in non-small cell lung cancer: from molecular mechanisms to clinical implications. International Journal of Cancer. PMID 35603909 DOI: 10.1002/ijc.34127  0.257
2012 Parsonage G, Machado LR, Hui JW, McLarnon A, Schmaler T, Balasothy M, To KF, Vlantis AC, van Hasselt CA, Lo KW, Wong WL, Hui EP, Chan AT, Lee SP. CXCR6 and CCR5 localize T lymphocyte subsets in nasopharyngeal carcinoma. The American Journal of Pathology. 180: 1215-22. PMID 22226739 DOI: 10.1016/j.ajpath.2011.11.032  0.255
2021 Kang W, Zhang J, Huang T, Zhou Y, Wong CC, Chan RCK, Dong Y, Wu F, Zhang B, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, et al. NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway. Oncogene. PMID 33452458 DOI: 10.1038/s41388-020-01579-3  0.254
2004 Chow LS, Lo KW, Kwong J, Wong AY, Huang DP. Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma. Oncology Reports. 12: 781-7. PMID 15375500  0.253
2008 Chan SY, Choy KW, Tsao SW, Tao Q, Tang T, Chung GT, Lo KW. Authentication of nasopharyngeal carcinoma tumor lines. International Journal of Cancer. Journal International Du Cancer. 122: 2169-71. PMID 18196576 DOI: 10.1002/Ijc.23374  0.251
2007 Mocanu JD, Yip KW, Alajez NM, Shi W, Li JH, Lunt SJ, Moriyama EH, Wilson BC, Milosevic M, Lo KW, van Rooijen N, Busson P, Bastianutto C, Liu FF. Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 921-9. PMID 17356543 DOI: 10.1038/mt.sj.6300119  0.251
2002 Choy KW, Pang CP, Yu CB, Wong HL, Ng JS, Fan DS, Lo KW, Chai JT, Wang J, Fu W, Lam DS. Loss of heterozygosity and mutations are the major mechanisms of RB1 gene inactivation in Chinese with sporadic retinoblastoma. Human Mutation. 20: 408. PMID 12402348 DOI: 10.1002/humu.9077  0.248
2015 Yung MK, Lo KW, Yip CW, Chung GT, Tong CY, Cheung PF, Cheung TT, Poon RT, So S, Fan ST, Cheung ST. Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer. Bmc Cancer. 15: 264. PMID 25885205 DOI: 10.1186/s12885-015-1294-x  0.245
2022 Mui CW, Chan WN, Chen B, Cheung AH, Yu J, Lo KW, Ke H, Kang W, To KF. Targeting YAP1/TAZ in non-small-cell lung carcinoma: from molecular mechanisms to precision medicine. International Journal of Cancer. PMID 35983734 DOI: 10.1002/ijc.34249  0.243
2012 Tsao SW, Tsang CM, Pang PS, Zhang G, Chen H, Lo KW. The biology of EBV infection in human epithelial cells. Seminars in Cancer Biology. 22: 137-43. PMID 22497025 DOI: 10.1016/j.semcancer.2012.02.004  0.243
2002 Kwong J, Lo KW, To KF, Teo PM, Johnson PJ, Huang DP. Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 131-7. PMID 11801549  0.242
2005 Hui AB, Or YY, Takano H, Tsang RK, To KF, Guan XY, Sham JS, Hung KW, Lam CN, van Hasselt CA, Kuo WL, Gray JW, Huang DP, Lo KW. Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma. Cancer Research. 65: 8125-33. PMID 16166286 DOI: 10.1158/0008-5472.Can-05-0648  0.24
2017 Hoe SLL, Tan LP, Abdul Aziz N, Liew K, Teow SY, Abdul Razak FR, Chin YM, Mohamed Shahrehan NA, Chu TL, Mohd Kornain NK, Peh SC, Koay CE, Lo KW, Ahmad M, Ng CC, et al. CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma. Scientific Reports. 7: 12372. PMID 28959019 DOI: 10.1038/s41598-017-12045-8  0.237
2014 Tsang CM, Deng W, Yip YL, Zeng MS, Lo KW, Tsao SW. Epstein-Barr virus infection and persistence in nasopharyngeal epithelial cells. Chinese Journal of Cancer. 33: 549-55. PMID 25223910 DOI: 10.5732/cjc.014.10169  0.237
2014 Cheung PF, Yip CW, Ng LW, Lo KW, Wong N, Choy KW, Chow C, Chan KF, Cheung TT, Poon RT, Fan ST, Cheung ST. Establishment and characterization of a novel primary hepatocellular carcinoma cell line with metastatic ability in vivo. Cancer Cell International. 14: 103. PMID 25349534 DOI: 10.1186/S12935-014-0103-Y  0.234
2014 Liang Q, Yao X, Tang S, Zhang J, Yau TO, Li X, Tang CM, Kang W, Lung RW, Li JW, Chan TF, Xing R, Lu Y, Lo KW, Wong N, et al. Integrative identification of Epstein-Barr virus-associated mutations and epigenetic alterations in gastric cancer. Gastroenterology. 147: 1350-62.e4. PMID 25173755 DOI: 10.1053/J.Gastro.2014.08.036  0.233
2017 Zhang J, Jia L, Lin W, Yip YL, Lo KW, Lau VM, Zhu D, Tsang CM, Zhou Y, Deng W, Lung HL, Lung ML, Cheung LM, Tsao SW. Epstein-Barr Virus encoded Latent Membrane Protein-1 upregulates glucose transporter-1 transcription via the mTORC1/NF-κB signaling pathways. Journal of Virology. PMID 28053105 DOI: 10.1128/Jvi.02168-16  0.233
2017 Lam P, Cheng S, Lo W, Tong C, Lo K, Lam Y, Leung L, Leung P. 314 - Topical application of mesenchymal stem cells for the treatment of chronic wounds- a pilot study Cytotherapy. 19. DOI: 10.1016/J.Jcyt.2017.02.320  0.233
2007 Cheng SH, Ng MH, Lau KM, Liu HS, Chan JC, Hui AB, Lo KW, Jiang H, Hou J, Chu RW, Wong WS, Chan NP, Ng HK. 4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4. Blood. 109: 2089-99. PMID 17077331 DOI: 10.1182/Blood-2006-04-018770  0.232
2021 Zha S, Chau HF, Chau WY, Chan LS, Lin J, Lo KW, Chi-Shing Cho W, Yip YL, Tsao SW, Farrell PJ, Feng L, Di JM, Law GL, Lung HL, Wong KL. Dual-Targeting Peptide-Guided Approach for Precision Delivery and Cancer Monitoring by Using a Safe Upconversion Nanoplatform. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2002919. PMID 33717845 DOI: 10.1002/advs.202002919  0.232
2003 Tong JH, Lo KW, Au FW, Huang DP, To KF. Re: Discrete alterations in the BZLF1 promoter in tumor and non-tumor-associated Epstein-Barr virus. Journal of the National Cancer Institute. 95: 1008-9; author reply. PMID 12837838  0.231
2002 Tong JH, Tsang RK, Lo KW, Woo JK, Kwong J, Chan MW, Chang AR, van Hasselt CA, Huang DP, To KF. Quantitative Epstein-Barr virus DNA analysis and detection of gene promoter hypermethylation in nasopharyngeal (NP) brushing samples from patients with NP carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2612-9. PMID 12171892  0.23
2020 Zhou Y, Zhang J, Li H, Huang T, Wong CC, Wu F, Wu M, Weng N, Liu L, Cheng ASL, Yu J, Wong N, Lo KW, Tang PMK, Kang W, et al. AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis. Oncogene. PMID 32313226 DOI: 10.1038/S41388-020-1293-5  0.228
2012 Vérillaud B, Gressette M, Morel Y, Paturel C, Herman P, Lo KW, Tsao SW, Wassef M, Jimenez-Pailhes AS, Busson P. Toll-like receptor 3 in Epstein-Barr virus-associated nasopharyngeal carcinomas: consistent expression and cytotoxic effects of its synthetic ligand poly(A:U) combined to a Smac-mimetic. Infectious Agents and Cancer. 7: 36. PMID 23198710 DOI: 10.1186/1750-9378-7-36  0.222
2021 Wong KCW, Hui EP, Lo KW, Lam WKJ, Johnson D, Li L, Tao Q, Chan KCA, To KF, King AD, Ma BBY, Chan ATC. Nasopharyngeal carcinoma: an evolving paradigm. Nature Reviews. Clinical Oncology. PMID 34194007 DOI: 10.1038/s41571-021-00524-x  0.217
2018 Ma BBY, Lim WT, Goh BC, Hui EP, Lo KW, Pettinger A, Foster NR, Riess JW, Agulnik M, Chang AYC, Chopra A, Kish JA, Chung CH, Adkins DR, Cullen KJ, et al. Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017770388. PMID 29584545 DOI: 10.1200/Jco.2017.77.0388  0.216
2008 Friboulet L, Pioche-Durieu C, Rodriguez S, Valent A, Souquère S, Ripoche H, Khabir A, Tsao SW, Bosq J, Lo KW, Busson P. Recurrent overexpression of c-IAP2 in EBV-associated nasopharyngeal carcinomas: critical role in resistance to Toll-like receptor 3-mediated apoptosis. Neoplasia (New York, N.Y.). 10: 1183-94. PMID 18953427  0.21
2002 Chan AS, To KF, Lo KW, Ding M, Li X, Johnson P, Huang DP. Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern Chinese. International Journal of Cancer. 102: 300-3. PMID 12397655 DOI: 10.1002/Ijc.10689  0.209
2003 Wong N, Hui AB, Fan B, Lo KW, Pang E, Leung SF, Huang DP, Johnson PJ. Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping. Cancer Genetics and Cytogenetics. 140: 124-32. PMID 12645650 DOI: 10.1016/S0165-4608(02)00657-X  0.206
2018 Pan Y, Tong JHM, Lung RWM, Kang W, Kwan JSH, Chak WP, Tin KY, Chung LY, Wu F, Ng SSM, Mak TWC, Yu J, Lo KW, Chan AWH, To KF. RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer. Molecular Cancer. 17: 102. PMID 30037330 DOI: 10.1186/S12943-018-0853-6  0.203
2002 Lee TL, Leung WK, Chan MW, Ng EK, Tong JH, Lo KW, Chung SC, Sung JJ, To KF. Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 1761-6. PMID 12060614  0.2
2018 Ahmad M, Suhaimi SN, Chu TL, Abdul Aziz N, Mohd Kornain NK, Samiulla DS, Lo KW, Ng CH, Khoo AS. Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma. Plos One. 13: e0191295. PMID 29329342 DOI: 10.1371/journal.pone.0191295  0.198
2020 Cheung ST, Chan SL, Lo KW. Contaminated and misidentified cell lines commonly use in cancer research. Molecular Carcinogenesis. PMID 32196757 DOI: 10.1002/mc.23189  0.192
2013 Zhang G, Tsang CM, Deng W, Yip YL, Lui VW, Wong SC, Cheung AL, Hau PM, Zeng M, Lung ML, Chen H, Lo KW, Takada K, Tsao SW. Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells. Plos One. 8: e62284. PMID 23658720 DOI: 10.1371/Journal.Pone.0062284  0.191
2020 Liu Y, Wang L, Lo KW, Lui VWY. Omics-wide quantitative B-cell infiltration analyses identify GPR18 for human cancer prognosis with superiority over CD20. Communications Biology. 3: 234. PMID 32398659 DOI: 10.1038/s42003-020-0964-7  0.19
2023 Chen B, Chan WN, Xie F, Mui CW, Liu X, Cheung AHK, Lung RWM, Chow C, Zhang Z, Fang C, Yu P, Shi S, Zhou S, Chen G, Wang Z, ... ... Lo KW, et al. The molecular classification of cancer-associated fibroblasts on a pan-cancer single-cell transcriptional atlas. Clinical and Translational Medicine. 13: e1516. PMID 38148640 DOI: 10.1002/ctm2.1516  0.19
2023 Yan H, Zhang JL, Leung KT, Lo KW, Yu J, To KF, Kang W. An Update of G-Protein-Coupled Receptor Signaling and Its Deregulation in Gastric Carcinogenesis. Cancers. 15. PMID 36765694 DOI: 10.3390/cancers15030736  0.189
2023 Shin WS, Xie F, Chen B, Yu J, Lo KW, Tse GMK, To KF, Kang W. Exploring the Microbiome in Gastric Cancer: Assessing Potential Implications and Contextualizing Microorganisms beyond and Epstein-Barr Virus. Cancers. 15. PMID 37894360 DOI: 10.3390/cancers15204993  0.189
2002 Chan BC, To KF, Pang JC, Chung YF, Lo KW, Tong JH, Huang DW, Lim PL, Chui YL. Generation of monoclonal antibodies against Hong Kong nasopharyngeal carcinoma-associated Epstein-Barr virus latent membrane protein 1 (LMP1). International Journal of Cancer. Journal International Du Cancer. 102: 492-8. PMID 12432552 DOI: 10.1002/ijc.10773  0.186
2023 Cheung AH, Wong KY, Liu X, Ji F, Hui CH, Zhang Y, Kwan JS, Chen B, Dong Y, Lung RW, Yu J, Lo KW, Wong CC, Kang W, To KF. MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5. Oncogenesis. 12: 35. PMID 37407566 DOI: 10.1038/s41389-023-00478-y  0.185
2024 Li L, Hong C, Xu J, Chung CY, Leung AK, Boncan DAT, Cheng L, Lo KW, Lai PBS, Wong J, Zhou J, Cheng AS, Chan TF, Yue F, Yip KY. Accurate identification of structural variations from cancer samples. Briefings in Bioinformatics. 25. PMID 38233091 DOI: 10.1093/bib/bbad520  0.182
2021 Yu KH, Shi CH, Wang B, Chow SH, Chung GT, Lung RW, Tan KE, Lim YY, Tsang AC, Lo KW, Yip KY. Quantifying full-length circular RNAs in cancer. Genome Research. PMID 34663689 DOI: 10.1101/gr.275348.121  0.182
2021 Domnic G, Jeng-Yeou Chear N, Abdul Rahman SF, Ramanathan S, Lo KW, Singh D, Mohana-Kumaran N. Combinations of indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of nasopharyngeal carcinoma cell lines. Journal of Ethnopharmacology. 114391. PMID 34224811 DOI: 10.1016/j.jep.2021.114391  0.177
2003 Tse GM, Kung FY, Chan AB, Law BK, Chang AR, Lo KW. Clonal analysis of bilateral mammary carcinomas by clinical evaluation and partial allelotyping. American Journal of Clinical Pathology. 120: 168-74. PMID 12931545 DOI: 10.1309/6YEP-MCHA-CPG2-BD15  0.176
2023 Mahajan S, Balcioglu HE, Oostvogels A, Dik WA, Chan KCA, Lo KW, Hui EP, Tsang A, Tong J, Lam WKJ, Wong K, Chan ATC, Ma BBY, Debets R. Frequency of Peripheral CD8+ T Cells Expressing Chemo-Attractant Receptors CCR1, 4 and 5 Increases in NPC Patients with EBV Clearance upon Radiotherapy. Cancers. 15. PMID 36980772 DOI: 10.3390/cancers15061887  0.175
2024 Chen B, Yu P, Chan WN, Xie F, Zhang Y, Liang L, Leung KT, Lo KW, Yu J, Tse GMK, Kang W, To KF. Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets. Signal Transduction and Targeted Therapy. 9: 6. PMID 38169461 DOI: 10.1038/s41392-023-01679-y  0.172
2021 Chen B, Chan WN, Mui CW, Liu X, Zhang J, Wang Y, Cheung AHK, Chan AKY, Chan RCK, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, ... ... Lo KW, et al. STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker. Molecular Cancer. 20: 147. PMID 34772410 DOI: 10.1186/s12943-021-01451-2  0.172
2023 Chen B, Liu X, Yu P, Xie F, Kwan JSH, Chan WN, Fang C, Zhang J, Cheung AHK, Chow C, Leung GWM, Leung KT, Shi S, Zhang B, Wang S, ... ... Lo KW, et al. H. pylori-induced NF-κB-PIEZO1-YAP1-CTGF axis drives gastric cancer progression and cancer-associated fibroblast-mediated tumour microenvironment remodelling. Clinical and Translational Medicine. 13: e1481. PMID 37983931 DOI: 10.1002/ctm2.1481  0.171
2022 Lee SD, Wu M, Lo KW, Yip KY. Accurate reconstruction of viral genomes in human cells from short reads using iterative refinement. Bmc Genomics. 23: 422. PMID 35668367 DOI: 10.1186/s12864-022-08649-8  0.171
2022 Bruce JP, To KF, Lui VWY, Chung GTY, Chan YY, Tsang CM, Yip KY, Ma BBY, Woo JKS, Hui EP, Mak MKF, Lee SD, Chow C, Velapasamy S, Or YYY, ... ... Lo KW, et al. Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nature Communications. 13: 4353. PMID 35896551 DOI: 10.1038/s41467-022-32156-9  0.169
2004 Choy KW, Pang CP, Fan DS, Lee TC, Wang JH, Abramson DH, Lo KW, To KF, Yu CB, Beaverson KL, Cheung KF, Lam DS. Microsatellite instability and MLH1 promoter methylation in human retinoblastoma. Investigative Ophthalmology & Visual Science. 45: 3404-9. PMID 15452042 DOI: 10.1167/iovs.03-1273  0.167
2005 Or YY, Hui ABY, Tam KY, Huang DP, Lo KW. Characterization of chromosome 3q and 12q amplicons in nasopharyngeal carcinoma cell lines International Journal of Oncology. 26: 49-56. PMID 15586224  0.161
2006 Wan J, Zhang W, Wu L, Bai T, Zhang M, Lo KW, Chui YL, Cui Y, Tao Q, Yamamoto M, Akira S, Wu Z. BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway. Molecular and Cellular Biology. 26: 448-56. PMID 16382137 DOI: 10.1128/Mcb.26.2.448-456.2006  0.157
2002 Pak MW, To KF, Lo YM, Chan LY, Tong JH, Lo KW, van Hasselt CA. Nasopharyngeal carcinoma in situ (NPCIS)--pathologic and clinical perspectives. Head & Neck. 24: 989-95. PMID 12410533 DOI: 10.1002/hed.10161  0.142
2005 Hui AB, Takano H, Lo KW, Kuo WL, Lam CN, Tong CY, Chang Q, Gray JW, Ng HK. Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4707-16. PMID 16000565 DOI: 10.1158/1078-0432.Ccr-05-0128  0.119
2019 Yoo SK, Kim CU, Kim HL, Kim S, Shin JY, Kim N, Yang JSW, Lo KW, Cho B, Matsuda F, Schuster SC, Kim C, Kim JI, Seo JS. NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants. Genome Medicine. 11: 64. PMID 31640730 DOI: 10.1186/s13073-019-0677-z  0.105
2005 Chan KC, Hui AB, Wong N, Lau TK, Leung TN, Lo KW, Lo YM. Investigation of the genomic representation of plasma DNA in pregnant women by comparative genomic hybridization analysis: a feasibility study. Clinical Chemistry. 51: 2398-401. PMID 16306110 DOI: 10.1373/Clinchem.2005.055434  0.097
2022 Teoh BY, Lim YM, Chong WY, Subramaniam M, Tan ZZ, Misran M, Suk VRE, Lo KW, Lee PF. Isolation of exosome from the culture medium of Nasopharyngeal cancer (NPC) C666-1 cells using inertial based Microfluidic channel. Biomedical Microdevices. 24: 12. PMID 35080702 DOI: 10.1007/s10544-022-00609-z  0.076
2004 Lo KW, To KF, Huang DP. Focus on nasopharyngeal carcinoma Cancer Cell. 5: 423-428. PMID 15144950 DOI: 10.1016/S1535-6108(04)00119-9  0.061
2004 Chan KC, Zhang J, Hui AB, Wong N, Lau TK, Leung TN, Lo KW, Huang DW, Lo YM. Size distributions of maternal and fetal DNA in maternal plasma. Clinical Chemistry. 50: 88-92. PMID 14709639 DOI: 10.1373/Clinchem.2003.024893  0.041
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