| Year |
Citation |
Score |
| 2024 |
Nowzari ZR, Hale M, Ellis J, Biaesch S, Vangaveti S, Reddy K, Chen AA, Berglund JA. Mutation of two intronic nucleotides alters RNA structure and dynamics inhibiting MBNL1 and RBFOX1 regulated splicing of the Insulin Receptor. Biorxiv : the Preprint Server For Biology. PMID 38260517 DOI: 10.1101/2024.01.08.574689 |
0.308 |
|
| 2023 |
Madhanagopal BR, Talbot H, Rodriguez A, Louis JM, Zeghal H, Vangaveti S, Reddy K, Chandrasekaran AR. Unusual Structural Properties of Switchback DNA. Biorxiv : the Preprint Server For Biology. PMID 38014227 DOI: 10.1101/2023.11.15.563609 |
0.367 |
|
| 2023 |
Schroader JH, Handley MT, Reddy K. Inosine triphosphate pyrophosphatase: A guardian of the cellular nucleotide pool and potential mediator of RNA function. Wiley Interdisciplinary Reviews. Rna. e1790. PMID 37092460 DOI: 10.1002/wrna.1790 |
0.382 |
|
| 2023 |
Mishra SK, Hicks SM, Frias JA, Vangaveti S, Nakamori M, Cleary JD, Reddy K, Berglund JA. Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy. Biorxiv : the Preprint Server For Biology. PMID 36778282 DOI: 10.1101/2023.02.02.526846 |
0.588 |
|
| 2022 |
Schroader JH, Jones LA, Meng R, Shorrock HK, Richardson JI, Shaughnessy SM, Lin Q, Begley TJ, Berglund JA, Fuchs G, Handley MT, Reddy K. Disease-associated inosine misincorporation into RNA hinders translation. Nucleic Acids Research. PMID 35979951 DOI: 10.1093/nar/gkac709 |
0.335 |
|
| 2020 |
Reddy K, Cleary JD, Berglund JA. Drug Screen Tugs at Common Thread for Repeat Disorders. Trends in Pharmacological Sciences. PMID 31926601 DOI: 10.1016/J.Tips.2019.12.004 |
0.532 |
|
| 2019 |
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570586 DOI: 10.1073/Pnas.1901893116 |
0.635 |
|
| 2019 |
Reddy K, Jenquin JR, Cleary JD, Berglund JA. Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules. International Journal of Molecular Sciences. 20. PMID 31426500 DOI: 10.3390/Ijms20164017 |
0.614 |
|
| 2019 |
Handley MT, Reddy K, Wills J, Rosser E, Kamath A, Halachev M, Falkous G, Williams D, Cox P, Meynert A, Raymond ES, Morrison H, Brown S, Allan E, Aligianis I, et al. ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy. Plos Genetics. 15: e1007605. PMID 30856165 DOI: 10.1371/Journal.Pgen.1007605 |
0.428 |
|
| 2017 |
Moss CF, Dalla Rosa I, Hunt LE, Yasukawa T, Young R, Jones AWE, Reddy K, Desai R, Virtue S, Elgar G, Voshol P, Taylor MS, Holt IJ, Reijns MAM, Spinazzola A. Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model. Nucleic Acids Research. PMID 29106596 DOI: 10.1093/Nar/Gkx1009 |
0.339 |
|
| 2016 |
Mackenzie KJ, Carroll P, Lettice L, Tarnauskaitė Ž, Reddy K, Dix F, Revuelta A, Abbondati E, Rigby RE, Rabe B, Kilanowski F, Grimes G, Fluteau A, Devenney PS, Hill RE, et al. Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response. The Embo Journal. PMID 26903602 DOI: 10.15252/Embj.201593339 |
0.417 |
|
| 2015 |
Harley ME, Murina O, Leitch A, Higgs MR, Bicknell LS, Yigit G, Blackford AN, Zlatanou A, Mackenzie KJ, Reddy K, Halachev M, McGlasson S, Reijns MA, Fluteau A, Martin CA, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nature Genetics. PMID 26595769 DOI: 10.1038/Ng.3451 |
0.403 |
|
| 2014 |
Reddy K, Schmidt MH, Geist JM, Thakkar NP, Panigrahi GB, Wang YH, Pearson CE. Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability. Nucleic Acids Research. 42: 10473-87. PMID 25147206 DOI: 10.1093/Nar/Gku658 |
0.697 |
|
| 2014 |
Zamiri B, Reddy K, Macgregor RB, Pearson CE. TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins. The Journal of Biological Chemistry. 289: 4653-9. PMID 24371143 DOI: 10.1074/Jbc.C113.502336 |
0.671 |
|
| 2014 |
Zamiri B, Reddy K, Pearson CE, Macgregor RB. The Structure of the Disease-Associated (GGGGCC)N Repeat from the C9ORF72 Gene Biophysical Journal. 106: 283a. DOI: 10.1016/J.Bpj.2013.11.1655 |
0.644 |
|
| 2013 |
Reddy K, Pearson CE. RAN translation: fragile X in the running. Neuron. 78: 405-8. PMID 23664607 DOI: 10.1016/J.Neuron.2013.04.034 |
0.546 |
|
| 2013 |
Reddy K, Zamiri B, Stanley SY, Macgregor RB, Pearson CE. The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures. The Journal of Biological Chemistry. 288: 9860-6. PMID 23423380 DOI: 10.1074/Jbc.C113.452532 |
0.672 |
|
| 2013 |
Slean MM, Reddy K, Wu B, Nichol Edamura K, Kekis M, Nelissen FH, Aspers RL, Tessari M, Schärer OD, Wijmenga SS, Pearson CE. Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome. Biochemistry. 52: 773-85. PMID 23339280 DOI: 10.1021/Bi301369B |
0.593 |
|
| 2011 |
Reddy K, Tam M, Bowater RP, Barber M, Tomlinson M, Nichol Edamura K, Wang YH, Pearson CE. Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats. Nucleic Acids Research. 39: 1749-62. PMID 21051337 DOI: 10.1093/Nar/Gkq935 |
0.647 |
|
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