| Year |
Citation |
Score |
| 2021 |
Son JH, Cheung A, Zhu JS, Haddadin MJ, Kurth MJ. Davis-Beirut Reaction Inspired Nitroso Diels-Alder Reaction. Tetrahedron Letters. 69. PMID 33854257 DOI: 10.1016/j.tetlet.2021.152951 |
0.375 |
|
| 2020 |
Son JH, Phuan PW, Zhu JS, Lipman E, Cheung A, Tsui KY, Tantillo DJ, Verkman AS, Haggie PM, Kurth MJ. 1-BENZYLSPIRO[PIPERIDINE-4,1'-PYRIDO[3,4-b]indole] 'co-potentiators' for minimal function CFTR mutants. European Journal of Medicinal Chemistry. 112888. PMID 33092904 DOI: 10.1016/j.ejmech.2020.112888 |
0.56 |
|
| 2019 |
Zhu JS, Larach JM, Tombari RJ, Gingrich PW, Bode SR, Tuck JR, Warren HT, Son JH, Duim WC, Fettinger JC, Haddadin MJ, Tantillo DJ, Kurth MJ, Olson DE. A Redox Isomerization Strategy for Accessing Modular Azobenzene Photoswitches with Near Quantitative Bidirectional Photoconversion. Organic Letters. PMID 31638403 DOI: 10.1021/Acs.Orglett.9B03387 |
0.59 |
|
| 2019 |
Kraemer N, Li CJ, Zhu JS, Larach JM, Tsui KY, Tantillo DJ, Haddadin MJ, Kurth MJ. Davis-Beirut Reaction: A Photochemical Brønsted Acid Catalyzed Route to -Aryl 2-Indazoles. Organic Letters. PMID 31339318 DOI: 10.1021/Acs.Orglett.9B02213 |
0.608 |
|
| 2019 |
Zhu JS, Haddadin MJ, Kurth MJ. Davis-Beirut Reaction: Diverse Chemistries of Highly Reactive Nitroso Intermediates in Heterocycle Synthesis. Accounts of Chemical Research. PMID 31328502 DOI: 10.1021/Acs.Accounts.9B00220 |
0.503 |
|
| 2019 |
Zhu JS, Lu JY, Tan JA, Rivera AA, Phuan PW, Shatskikh ME, Son JH, Haggie PM, Verkman AS, Kurth MJ. Synthesis and evaluation of tetrahydropyrazolopyridine inhibitors of anion exchange protein SLC26A4 (pendrin). Bioorganic & Medicinal Chemistry Letters. PMID 31281021 DOI: 10.1016/J.Bmcl.2019.07.003 |
0.417 |
|
| 2019 |
Zhu JS, Li CJ, Tsui KY, Kraemer N, Son JH, Haddadin MJ, Tantillo DJ, Kurth MJ. Accessing Multiple Classes of 2H-Indazoles: Mechanistic Implications for the Cadogan and Davis-Beirut Reactions. Journal of the American Chemical Society. PMID 30912441 DOI: 10.1021/Jacs.8B13481 |
0.621 |
|
| 2019 |
Monzer A, Jabotian N, Zhu JS, Kurth MJ, Kheir WA, Haddadin M, Gali-Muhtasib H. Abstract 4797: A novel Diiminoquinone targets colorectal cancer stem cells Cancer Research. 79: 4797-4797. DOI: 10.1158/1538-7445.Am2019-4797 |
0.37 |
|
| 2018 |
Zhu JS, Kraemer N, Li CJ, Haddadin MJ, Kurth MJ. Photochemical Preparation of 1,2-Dihydro-3H-indazol-3-ones in Aqueous Solvent at Room Temperature. The Journal of Organic Chemistry. PMID 30468072 DOI: 10.1021/Acs.Joc.8B02356 |
0.443 |
|
| 2018 |
Zhu JS, Kraemer N, Shatskikh ME, Li CJ, Son JH, Haddadin MJ, Tantillo DJ, Kurth MJ. N-N Bond Formation between Primary Amines and Nitrosos: Direct Synthesis of 2-Substituted Indazolones with Mechanistic Insights. Organic Letters. PMID 30067041 DOI: 10.1021/Acs.Orglett.8B01655 |
0.586 |
|
| 2018 |
Zhu JS, Duong MR, Teuthorn AP, Lu JY, Son JH, Haddadin MJ, Kurth MJ. Davis-Beirut Reaction: Alkoxide versus Hydroxide Addition to the Key o-Nitrosoimine Intermediate. Organic Letters. PMID 29431446 DOI: 10.1021/Acs.Orglett.8B00036 |
0.416 |
|
| 2017 |
Zhu JS, Son JH, Teuthorn AP, Haddadin MJ, Kurth MJ, Tantillo DJ. Correction to "Diverting Reactive Intermediates Toward Unusual Chemistry: Unexpected Anthranil Products from Davis-Beirut Reaction". The Journal of Organic Chemistry. PMID 29091433 DOI: 10.1021/Acs.Joc.7B02695 |
0.576 |
|
| 2017 |
Zhu JS, Son JH, Teuthorn AP, Haddadin MJ, Kurth MJ, Tantillo DJ. Diverting Reactive Intermediates Toward Unusual Chemistry - Unexpected Anthranil Products from Davis-Beirut Reaction. The Journal of Organic Chemistry. PMID 28922917 DOI: 10.1021/Acs.Joc.7B01521 |
0.597 |
|
| 2017 |
Son JH, Zhu JS, Phuan PW, Cil O, Teuthorn AP, Ku CK, Lee S, Verkman AS, Kurth MJ. High-potency phenylquinoxalinone cystic fibrosis transmembrane conductance regulator (CFTR) activators. Journal of Medicinal Chemistry. PMID 28230981 DOI: 10.1021/Acs.Jmedchem.6B01759 |
0.435 |
|
| 2017 |
Shuai Z, Wang J, Badamagunta M, Choi J, Yang G, Zhang W, Kenny TP, Guggenheim K, Kurth MJ, Ansari AA, Voss J, Coppel RL, Invernizzi P, Leung PS, Gershwin ME. The Fingerprint of Antimitochondrial Antibodies and the Etiology of Primary Biliary Cholangitis. Hepatology (Baltimore, Md.). PMID 28100006 DOI: 10.1002/Hep.29059 |
0.771 |
|
| 2016 |
Cil O, Phuan PW, Son JH, Zhu JS, Ku CK, Tabib NA, Teuthorn AP, Ferrera L, Zachos NC, Lin R, Galietta LJ, Donowitz M, Kurth MJ, Verkman AS. Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 27815136 DOI: 10.1016/J.Trsl.2016.10.003 |
0.389 |
|
| 2016 |
Bagdasarian AL, Nguyen HH, Palazzo TA, Fettinger JC, Haddadin MJ, Kurth MJ. One-Pot Synthesis of Benzo[4,5]imidazo[2,1-a]isoquinolines and Isoquinolino[3,4-b]quinoxalines via Tandem Cyclization Strategies. The Journal of Organic Chemistry. PMID 27030441 DOI: 10.1021/Acs.Joc.6B00338 |
0.788 |
|
| 2015 |
Palazzo TA, Patra D, Yang JS, El Khoury E, Appleton MG, Haddadin MJ, Tantillo DJ, Kurth MJ. Dibenzonaphthyridinones: Heterocycle-to-Heterocycle Synthetic Strategies and Photophysical Studies. Organic Letters. PMID 26574652 DOI: 10.1021/Acs.Orglett.5B02680 |
0.779 |
|
| 2015 |
Nguyen HH, Fettinger JC, Haddadin MJ, Kurth MJ. Expedient one-pot synthesis of indolo[3,2-c]isoquinolines via a base-promoted N-alkylation/tandem cyclization. Tetrahedron Letters. 56: 5429-5433. PMID 26366017 DOI: 10.1016/J.Tetlet.2015.08.006 |
0.606 |
|
| 2015 |
Wedler HB, Palazzo TA, Pemberton RP, Hamann CS, Kurth MJ, Tantillo DJ. Predicting hydration propensities of biologically relevant α-ketoamides. Bioorganic & Medicinal Chemistry Letters. 25: 4153-7. PMID 26306983 DOI: 10.1016/J.Bmcl.2015.08.010 |
0.767 |
|
| 2015 |
Palazzo TA, Truong TT, Wong SMT, Mack ET, Lodewyk MW, Harrison JG, Gamage RA, Siegel JB, Kurth MJ, Tantillo DJ. Reassigning the structures of natural products using NMR chemical shifts computed with quantum mechanics: A laboratory exercise Journal of Chemical Education. 92: 561-566. DOI: 10.1021/Ed4006584 |
0.76 |
|
| 2015 |
Wedler HB, Palazzo TA, Pemberton RP, Hamann CS, Kurth MJ, Tantillo DJ. Predicting hydration propensities of biologically relevant α-ketoamides Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.08.010 |
0.743 |
|
| 2014 |
Coffman KC, Duong V, Bagdasarian AL, Fettinger JC, Haddadin MJ, Kurth MJ. Heterocycle-to-Heterocycle Route to Quinoline-4-amines: Reductive Heterocyclization of 3-(2-Nitrophenyl)isoxazoles. European Journal of Organic Chemistry. 2014: 7651-7657. PMID 26257574 DOI: 10.1002/Ejoc.201403065 |
0.386 |
|
| 2014 |
Ye L, Hu B, El-Badri F, Hudson BM, Phuan PW, Verkman AS, Tantillo DJ, Kurth MJ. ΔF508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles. Bioorganic & Medicinal Chemistry Letters. 24: 5840-4. PMID 25452003 DOI: 10.1016/J.Bmcl.2014.09.067 |
0.609 |
|
| 2014 |
Roth A, Ott S, Farber KM, Palazzo TA, Conrad WE, Haddadin MJ, Tantillo DJ, Cross CE, Eiserich JP, Kurth MJ. Inhibition of myeloperoxidase: evaluation of 2H-indazoles and 1H-indazolones. Bioorganic & Medicinal Chemistry. 22: 6422-9. PMID 25438766 DOI: 10.1016/J.Bmc.2014.09.044 |
0.791 |
|
| 2014 |
Coffman KC, Nguyen HH, Phuan PW, Hudson BM, Yu GJ, Bagdasarian AL, Montgomery D, Lodewyk MW, Yang B, Yoo CL, Verkman AS, Tantillo DJ, Kurth MJ. Constrained bithiazoles: small molecule correctors of defective ΔF508-CFTR protein trafficking. Journal of Medicinal Chemistry. 57: 6729-38. PMID 25061695 DOI: 10.1021/Jm5007885 |
0.775 |
|
| 2014 |
Farber KM, Haddadin MJ, Kurth MJ. Davis-Beirut reaction: route to thiazolo-, thiazino-, and thiazepino-2H-indazoles. The Journal of Organic Chemistry. 79: 6939-45. PMID 25019525 DOI: 10.1021/Jo501014E |
0.365 |
|
| 2014 |
Patra D, Palazzo TA, Malaeb NN, Haddadin MJ, Tantillo DJ, Kurth MJ. Cyclic azacyanines: experimental and computational studies on spectroscopic properties and unique reactivity. Journal of Fluorescence. 24: 1285-96. PMID 24910112 DOI: 10.1007/S10895-014-1413-0 |
0.774 |
|
| 2013 |
Nguyen HH, Palazzo TA, Kurth MJ. Facile one-pot assembly of imidazotriazolobenzodiazepines via indium(III)-catalyzed multicomponent reactions. Organic Letters. 15: 4492-5. PMID 23961714 DOI: 10.1021/Ol402045H |
0.804 |
|
| 2013 |
Snyder DS, Tradtrantip L, Battula S, Yao C, Phuan PW, Fettinger JC, Kurth MJ, Verkman AS. ABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27. Acs Medicinal Chemistry Letters. 4: 456-459. PMID 23814642 DOI: 10.1021/Ml400069K |
0.305 |
|
| 2013 |
Coffman KC, Palazzo TA, Hartley TP, Fettinger JC, Tantillo DJ, Kurth MJ. Heterocycle-heterocycle strategies: (2-nitrophenyl)isoxazole precursors to 4-aminoquinolines, 1H-indoles, and quinolin-4(1H)-ones. Organic Letters. 15: 2062-5. PMID 23557405 DOI: 10.1021/Ol400787Y |
0.791 |
|
| 2013 |
Nguyen HH, Kurth MJ. Microwave-assisted synthesis of 3-nitroindoles from N-aryl enamines via intramolecular arene-alkene coupling. Organic Letters. 15: 362-5. PMID 23268775 DOI: 10.1021/Ol303314X |
0.609 |
|
| 2013 |
Chen RC, Naiyanetr P, Shu SA, Wang J, Yang GX, Kenny TP, Guggenheim KC, Butler JD, Bowlus C, Tao MH, Kurth MJ, Ansari AA, Kaplan M, Coppel RL, Lleo A, et al. Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 57: 1498-508. PMID 23184636 DOI: 10.1002/Hep.26157 |
0.58 |
|
| 2013 |
Ye L, Dickerson T, Kaur H, Takada YK, Fujita M, Liu R, Knapp JM, Lam KS, Schore NE, Kurth MJ, Takada Y. Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3. Bioorganic & Medicinal Chemistry Letters. 23: 340-5. PMID 23164706 DOI: 10.1016/J.Bmcl.2012.10.080 |
0.776 |
|
| 2013 |
Coffman KC, Palazzo TA, Hartley TP, Fettinger JC, Tantillo DJ, Kurth MJ. ChemInform Abstract: Heterocycle-Heterocycle Strategies: (2-Nitrophenyl)isoxazole Precursors to 4-Aminoquinolines, 1H-Indoles, and Quinolin-4(1H)-ones. Cheminform. 44: no-no. DOI: 10.1002/chin.201333171 |
0.456 |
|
| 2012 |
Avila B, El-Dakdouki MH, Nazer MZ, Harrison JG, Tantillo DJ, Haddadin MJ, Kurth MJ. Acid and base catalyzed Davis-Beirut reaction: experimental and theoretical mechanistic studies and synthesis of novel 3-amino-2H-indazoles. Tetrahedron Letters. 53: 6475-6478. PMID 23139435 DOI: 10.1016/J.Tetlet.2012.09.026 |
0.798 |
|
| 2012 |
Haddadin MJ, Conrad WE, Kurth MJ. The Davis-Beirut Reaction: a novel entry into 2H-indazoles and indazolones. Recent biological activity of indazoles. Mini Reviews in Medicinal Chemistry. 12: 1293-300. PMID 23092440 DOI: 10.2174/138955712802762059 |
0.783 |
|
| 2012 |
Knapp JM, Zhu JS, Tantillo DJ, Kurth MJ. Multicomponent assembly of highly substituted indoles by dual palladium-catalyzed coupling reactions. Angewandte Chemie (International Ed. in English). 51: 10588-91. PMID 23001913 DOI: 10.1002/Anie.201204633 |
0.774 |
|
| 2012 |
Avila B, Roth A, Streets H, Dwyer DS, Kurth MJ. Triazolbenzo[d]thiazoles: efficient synthesis and biological evaluation as neuroprotective agents. Bioorganic & Medicinal Chemistry Letters. 22: 5976-8. PMID 22892117 DOI: 10.1016/J.Bmcl.2012.07.022 |
0.733 |
|
| 2012 |
Conrad WE, Rodriguez KX, Nguyen HH, Fettinger JC, Haddadin MJ, Kurth MJ. A one-pot-three-step route to triazolotriazepinoindazolones from oxazolino-2H-indazoles. Organic Letters. 14: 3870-3. PMID 22823414 DOI: 10.1021/Ol3015804 |
0.804 |
|
| 2012 |
Shoker TA, Ghattass KI, Fettinger JC, Kurth MJ, Haddadin MJ. Unusual Friedlander reactions: a route to novel quinoxaline-based heterocycles. Organic Letters. 14: 3704-7. PMID 22783916 DOI: 10.1021/Ol301550E |
0.386 |
|
| 2012 |
Ibarra-Soza JM, Morris AA, Jayalath P, Peacock H, Conrad WE, Donald MB, Kurth MJ, Beal PA. 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & Biomolecular Chemistry. 10: 6491-7. PMID 22766576 DOI: 10.1039/C2Ob25647A |
0.759 |
|
| 2012 |
Guggenheim KG, Toru H, Kurth MJ. One-pot, two-step cascade synthesis of quinazolinotriazolobenzodiazepines. Organic Letters. 14: 3732-5. PMID 22746550 DOI: 10.1021/Ol301592Z |
0.805 |
|
| 2012 |
Coffman KC, Hartley TP, Dallas JL, Kurth MJ. Isoxazolodihydropyridinones: 1,3-dipolar cycloaddition of nitrile oxides onto 2,4-dioxopiperidines. Acs Combinatorial Science. 14: 280-4. PMID 22352295 DOI: 10.1021/Co200200U |
0.385 |
|
| 2012 |
Davison HR, Solano DM, Phuan PW, Verkman AS, Kurth MJ. Fluorinated ΔF508-CFTR correctors and potentiators for PET imaging. Bioorganic & Medicinal Chemistry Letters. 22: 1602-5. PMID 22281185 DOI: 10.1016/J.Bmcl.2011.12.128 |
0.767 |
|
| 2012 |
Knapp JM, Wood AB, Phuan PW, Lodewyk MW, Tantillo DJ, Verkman AS, Kurth MJ. Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ΔF508 cystic fibrosis transmembrane conductance regulator protein. Journal of Medicinal Chemistry. 55: 1242-51. PMID 22214395 DOI: 10.1021/Jm201372Q |
0.73 |
|
| 2012 |
Knapp JM, Zhu JS, Wood AB, Kurth MJ. Expedient synthesis of a 72-membered isoxazolino-β-ketoamide library by a 2·3-component reaction. Acs Combinatorial Science. 14: 85-8. PMID 22181856 DOI: 10.1021/Co200199H |
0.739 |
|
| 2012 |
Solano DM, Wood FE, Kurth MJ. Correction to “Careers in Chemistry”: A Course Providing Students with Real-World Foundations Journal of Chemical Education. 89: 420-420. DOI: 10.1021/Ed200751N |
0.75 |
|
| 2012 |
Butler JD, Choung W, Kurth MJ. Correction to Flash Chromatography: A Novel Pressurization Apparatus Journal of Chemical Education. 89: 419-419. DOI: 10.1021/Ed200750D |
0.544 |
|
| 2011 |
Haddadin MJ, El-Khatib M, Shoker TA, Beavers CM, Olmstead MM, Fettinger JC, Farber KM, Kurth MJ. Quinoxalino[2,3-c]cinnolines and their 5-N-oxide: alkoxylation of methyl-substituted quinoxalino[2,3-c]cinnolines to acetals and orthoesters. The Journal of Organic Chemistry. 76: 8421-7. PMID 21905671 DOI: 10.1021/Jo201687X |
0.355 |
|
| 2011 |
Knapp JM, Fettinger JC, Kurth MJ. Multicomponent macrocyclization reactions (MCMRs) employing highly reactive acyl ketene and nitrile oxide intermediates. Organic Letters. 13: 4732-5. PMID 21827181 DOI: 10.1021/Ol202024A |
0.726 |
|
| 2011 |
Naiyanetr P, Butler JD, Meng L, Pfeiff J, Kenny TP, Guggenheim KG, Reiger R, Lam K, Kurth MJ, Ansari AA, Coppel RL, López-Hoyos M, Gershwin ME, Leung PS. Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity. Journal of Autoimmunity. 37: 209-16. PMID 21763105 DOI: 10.1016/J.Jaut.2011.06.001 |
0.776 |
|
| 2011 |
Meng L, Fettinger JC, Kurth MJ. Ethyl 1-benzyl-1,2,3,3a,4,10b-hexa-hydro-pyrrolo-[2',3':3,4]pyrrolo-[1,2-a]benzimidazole-2-carboxyl-ate. Acta Crystallographica. Section E, Structure Reports Online. 67: o1214. PMID 21754512 DOI: 10.1107/S1600536811014292 |
0.604 |
|
| 2011 |
Phuan PW, Yang B, Knapp JM, Wood AB, Lukacs GL, Kurth MJ, Verkman AS. Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis. Molecular Pharmacology. 80: 683-93. PMID 21730204 DOI: 10.1124/Mol.111.073056 |
0.697 |
|
| 2011 |
Snyder DS, Tradtrantip L, Yao C, Kurth MJ, Verkman AS. Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease. Journal of Medicinal Chemistry. 54: 5468-77. PMID 21707078 DOI: 10.1021/Jm200505E |
0.349 |
|
| 2011 |
Guggenheim KG, Butler JD, Painter PP, Lorsbach BA, Tantillo DJ, Kurth MJ. Synthesis of spiro-fused pyrazolidoylisoxazolines. The Journal of Organic Chemistry. 76: 5803-12. PMID 21650164 DOI: 10.1021/Jo200924Y |
0.793 |
|
| 2011 |
Conrad WE, Fukazawa R, Haddadin MJ, Kurth MJ. The Davis-Beirut reaction: N1,N2-disubstituted-1H-indazolones via 1,6-electrophilic addition to 3-alkoxy-2H-indazoles. Organic Letters. 13: 3138-41. PMID 21612219 DOI: 10.1021/Ol2010424 |
0.785 |
|
| 2011 |
Avila B, Solano DM, Haddadin MJ, Kurth MJ. Facile syntheses of novel benzo-1,3-dioxolo-, benzothiazolo-, pyrido-, and quinolino-fused 5H-benzo[d]-pyrazolo[5,1-b][1,3]-oxazines and 1H-pyrazoles. Organic Letters. 13: 1060-3. PMID 21294577 DOI: 10.1021/Ol103108Z |
0.809 |
|
| 2011 |
Ferreira AJ, Solano DM, Oakdale JS, Kurth MJ. Novel trinitrogen-containing triheterocycles via the intramolecular nitrile oxide cycloaddition reaction Synthesis. 3241-3246. DOI: 10.1055/S-0030-1260188 |
0.798 |
|
| 2011 |
Haddadin MJ, Zerdan RMB, Kurth MJ, Fettinger JC. Erratum: Efficient syntheses of the unknown quinolino[2,3-c]-cinnolines: Synthesis of neocryptolepines (Inorganic Chemistry (5505)) Organic Letters. 13. DOI: 10.1021/Ol2030185 |
0.343 |
|
| 2011 |
Lodewyk MW, Kurth MJ, Tantillo DJ. Erratum: Mechanisms for formation of diazocinones, pyridazines, and pyrazolines from tetrazines-oxyanion-accelerated pericyclic cascades? (J. Org. Chem. (2009) 74 (4804-4811) 10.1021/j0900565y) Journal of Organic Chemistry. 76. DOI: 10.1021/Jo202310C |
0.463 |
|
| 2011 |
Solano DM, Wood FE, Kurth MJ. "Careers in chemistry": A course providing students with real-world foundations Journal of Chemical Education. 88: 1376-1379. DOI: 10.1021/Ed1001366 |
0.757 |
|
| 2011 |
Conrad WE, Fukazawa R, Haddadin MJ, Kurth MJ. ChemInform Abstract: The Davis-Beirut Reaction: N1,N2-Disubstituted-1H-indazolones via 1,6-Electrophilic Addition to 3-alkoxy-2H-indazoles. Cheminform. 42: no-no. DOI: 10.1002/chin.201140122 |
0.757 |
|
| 2011 |
Avila B, Solano DM, Haddadin MJ, Kurth MJ. ChemInform Abstract: Facile Syntheses of Novel Benzo-1,3-dioxolo-, Benzothiazolo-, Pyrido-, and Quinolino-Fused 5H-Benzo[d]pyrazolo[5,1-b][1,3]-oxazines and 1H-Pyrazoles. Cheminform. 42: no-no. DOI: 10.1002/chin.201123111 |
0.783 |
|
| 2010 |
Yu GJ, Yang B, Verkman AS, Kurth MJ. Isoxazolopyrimidines as Novel ΔF508-CFTR Correctors. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2010: 1063-1066. PMID 23710112 DOI: 10.1055/S-0029-1219781 |
0.357 |
|
| 2010 |
Haddadin MJ, Bou Zerdan RM, Kurth MJ, Fettinger JC. Efficient syntheses of the unknown quinolino[2,3-c]cinnolines; synthesis of neocryptolepines. Organic Letters. 12: 5502-5. PMID 21067220 DOI: 10.1021/Ol102376A |
0.37 |
|
| 2010 |
Carpenter RD, Kurth MJ. A rapid and efficient route to benzazole heterocycles. Nature Protocols. 5: 1731-6. PMID 21030949 DOI: 10.1038/Nprot.2010.132 |
0.383 |
|
| 2010 |
Yao N, Fung G, Malekan H, Ye L, Kurth MJ, Lam KS. Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation. Carbohydrate Research. 345: 2277-81. PMID 20832778 DOI: 10.1016/J.Carres.2010.07.040 |
0.503 |
|
| 2010 |
Butler JD, Coffman KC, Ziebart KT, Toney MD, Kurth MJ. Orthogonally protected thiazole and isoxazole diamino acids: an efficient synthetic route. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 9002-5. PMID 20623732 DOI: 10.1002/Chem.201001492 |
0.604 |
|
| 2010 |
Butler JD, Conrad WE, Lodewyk MW, Fettinger JC, Tantillo DJ, Kurth MJ. Synthesis of substituted chromanones: an organocatalytic aldol/oxa-Michael reaction. Organic Letters. 12: 3410-3. PMID 20617821 DOI: 10.1021/Ol101221C |
0.806 |
|
| 2010 |
Carpenter RD, Natarajan A, Lau EY, Andrei M, Solano DM, Lightstone FC, Denardo SJ, Lam KS, Kurth MJ. Halogenated benzimidazole carboxamides target integrin alpha4beta1 on T-cell and B-cell lymphomas. Cancer Research. 70: 5448-56. PMID 20530664 DOI: 10.1158/0008-5472.Can-09-3736 |
0.774 |
|
| 2010 |
Donald MB, Conrad WE, Oakdale JS, Butler JD, Haddadin MJ, Kurth MJ. Nucleophilic substitution of oxazino-/oxazolino-/benzoxazin [3,2-b]indazoles: an effective route to 1H-indazolones. Organic Letters. 12: 2524-7. PMID 20438102 DOI: 10.1021/Ol100751N |
0.813 |
|
| 2010 |
Ye L, Knapp JM, Sangwung P, Fettinger JC, Verkman AS, Kurth MJ. Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles. Journal of Medicinal Chemistry. 53: 3772-81. PMID 20373765 DOI: 10.1021/Jm100235H |
0.738 |
|
| 2010 |
Ziebart KT, Dixon SM, Avila B, El-Badri MH, Guggenheim KG, Kurth MJ, Toney MD. Targeting multiple chorismate-utilizing enzymes with a single inhibitor: validation of a three-stage design. Journal of Medicinal Chemistry. 53: 3718-29. PMID 20359225 DOI: 10.1021/Jm100158V |
0.769 |
|
| 2010 |
Meng L, Lorsbach BA, Sparks TC, Fettinger JC, Kurth MJ. Parallel Synthesis of bis-heterocyclic isoxazolylmethyl- and isoxazolinylmethylpyrazoles. Journal of Combinatorial Chemistry. 12: 129-36. PMID 20000375 DOI: 10.1021/Cc900133K |
0.636 |
|
| 2010 |
Ye L, Haddadin MJ, Lodewyk MW, Ferreira AJ, Fettinger JC, Tantillo DJ, Kurth MJ. Cyclopenta[b]pyrroles from triazines: synthetic and mechanistic studies. Organic Letters. 12: 164-7. PMID 19961148 DOI: 10.1021/Ol902559U |
0.632 |
|
| 2010 |
Mills AD, Yoo C, Butler JD, Yang B, Verkman AS, Kurth MJ. Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorganic & Medicinal Chemistry Letters. 20: 87-91. PMID 19954980 DOI: 10.1016/J.Bmcl.2009.11.020 |
0.778 |
|
| 2010 |
Kurth MJ. Linker Strategies in Solid-Phase Organic Synthesis Linker Strategies in Solid-Phase Organic Synthesis . Edited by Peter J. H. Scott (University of Michigan, Ann Arbor). John Wiley & Sons, Ltd.: Chichester. 2009. xxvii + 678 pp. $205. ISBN 978-0-470-51116-9 . Journal of the American Chemical Society. 132: 10615-10615. DOI: 10.1021/Ja104455S |
0.305 |
|
| 2010 |
Butler JD, Choung W, Kurth MJ. Flash chromatography: A novel pressurization apparatus Journal of Chemical Education. 87: 1265. DOI: 10.1021/Ed100416X |
0.546 |
|
| 2010 |
Haddadin MJ, El-Nachef C, Kisserwani H, Chaaban Y, Kurth MJ, Fettinger JC. 2-Benzyliden-2H-thieto[3,2-b]quinoline: A new heterocycle and its rearrangement to 2-phenylthieno[3,2-b]quinoline Tetrahedron Letters. 51: 6687-6689. DOI: 10.1016/J.Tetlet.2010.10.039 |
0.32 |
|
| 2010 |
Milinkevich KA, Yoo CL, Sparks TC, Lorsbach BA, Kurth MJ. ChemInform Abstract: Synthesis and Biological Activity of 2-(4,5-Dihydroisoxazol-5-yl)-1,3,4-oxadiazoles. Cheminform. 41. DOI: 10.1002/chin.201008139 |
0.798 |
|
| 2010 |
KANTOROWSKI EJ, BROWN SP, KURTH MJ. ChemInform Abstract: Use of Diisocyanates for in situ Preparation of Nitrile Oxides: Preparation of Isoxazoles and Isoxazolines. Cheminform. 29: no-no. DOI: 10.1002/chin.199850154 |
0.755 |
|
| 2010 |
KANTOROWSKI EJ, BORHAN B, NAZARIAN S, KURTH MJ. ChemInform Abstract: Cyclopropylcarbinyl Radical-Mediated Ring Expansion to Seven-Membered Carbocycles. Cheminform. 29: no-no. DOI: 10.1002/chin.199829094 |
0.752 |
|
| 2010 |
BEEBE X, CHIAPPARI CL, OLMSTEAD MM, KURTH MJ, SCHORE NE. ChemInform Abstract: Polymer-Supported Synthesis of Cyclic Ethers: Electrophilic Cyclization of Tetrahydrofuroisoxazolines. Cheminform. 26: no-no. DOI: 10.1002/chin.199549089 |
0.575 |
|
| 2010 |
BEEBE X, SCHORE NE, KURTH MJ. ChemInform Abstract: Polymer-Supported Synthesis of Cyclic Ethers: Electrophilic Cyclization of Isoxazolines. Cheminform. 26: no-no. DOI: 10.1002/chin.199549088 |
0.576 |
|
| 2010 |
MOON H, EISENBERG SWE, WILSON ME, SCHORE NE, KURTH MJ. ChemInform Abstract: Preparation of Nonracemic 3,5-Disubsituted-γ-butyrolactones: An Effective Sequent Auxiliary for Amide Alkylation and Iodolactonization. Cheminform. 26: no-no. DOI: 10.1002/chin.199520108 |
0.574 |
|
| 2010 |
MOON H, SCHORE NE, KURTH MJ. ChemInform Abstract: A Polymer-Supported C2-Symmetric Chiral Auxiliary: Preparation of Nonracemic 3,5-Disubstituted γ-Butyrolactones. Cheminform. 26: no-no. DOI: 10.1002/chin.199517117 |
0.543 |
|
| 2010 |
BEEBE X, CHIAPPARI CL, KURTH MJ, SCHORE NE. ChemInform Abstract: An Intramolecular 1,3-Dipolar Cycloaddition/Electrophilic Cyclization Sequence To Give Cyclic Ethers. Cheminform. 25: no-no. DOI: 10.1002/chin.199417150 |
0.568 |
|
| 2010 |
MOON H, SCHORE NE, KURTH MJ. ChemInform Abstract: A Polymer-Supported Chiral Auxiliary Applied to the Iodolactonization Reaction: Preparation of γ-Butyrolactones. Cheminform. 24: no-no. DOI: 10.1002/chin.199311189 |
0.57 |
|
| 2010 |
Solano DM, Butler JD, Haddadin MJ, Kurth MJ, Baucom KD, Faul MM. One-pot synthesis of 5H-indazolo-[3,2-b]benzo[d]-1,3-oxazine: Two efficient preparative methods Organic Syntheses. 87: 339-349. DOI: 10.1002/0471264229.Os087.36 |
0.795 |
|
| 2009 |
Meng L, Wang SC, Fettinger JC, Kurth MJ, Tantillo DJ. Controlling Selectivity for Cycloadditions of Nitrones and Alkenes Tethered by Benzimidazoles: Combining Experiment and Theory. European Journal of Organic Chemistry. 2009. PMID 24327801 DOI: 10.1002/Ejoc.200801211 |
0.672 |
|
| 2009 |
Milinkevich KA, Yoo CL, Sparks TC, Lorsbach BA, Kurth MJ. Synthesis and biological activity of 2-(4,5-dihydroisoxazol-5-yl)-1,3,4-oxadiazoles. Bioorganic & Medicinal Chemistry Letters. 19: 5796-8. PMID 19700317 DOI: 10.1016/J.Bmcl.2009.07.139 |
0.806 |
|
| 2009 |
Yu GJ, Iwamoto S, Robins LI, Fettinger JC, Sparks TC, Lorsbach BA, Kurth MJ. 3-(Arylthiomethyl)isoxazole-4,5-dicarboxamides: chemoselective nucleophilic chemistry and insecticidal activity. Journal of Agricultural and Food Chemistry. 57: 7422-6. PMID 19624156 DOI: 10.1021/Jf901512T |
0.601 |
|
| 2009 |
Oakdale JS, Solano DM, Fettinger JC, Haddadin MJ, Kurth MJ. An oxazolo[3,2-b]indazole route to 1H-indazolones. Organic Letters. 11: 2760-3. PMID 19505119 DOI: 10.1021/Ol900891S |
0.792 |
|
| 2009 |
Lodewyk MW, Kurth MJ, Tantillo DJ. Mechanisms for formation of diazocinones, pyridazines, and pyrazolines from tetrazines--oxyanion-accelerated pericyclic cascades? The Journal of Organic Chemistry. 74: 4804-11. PMID 19485385 DOI: 10.1021/Jo900565Y |
0.539 |
|
| 2009 |
El-Badri MH, Kurth MJ. Synthesis of thiazolo- and 7,8-dihydrothiazolo[4,5-e]benzoisoxazoles. Journal of Combinatorial Chemistry. 11: 228-38. PMID 19154120 DOI: 10.1021/Cc800141S |
0.308 |
|
| 2009 |
Milinkevich KA, Kurth MJ. Preparation of a spiroisoxazolinopiperidinylbenzamide-based scaffold Synlett. 3019-3023. DOI: 10.1055/S-0029-1218290 |
0.814 |
|
| 2009 |
Butler JD, Donald MB, Ding Z, Fettinger JC, Kurth MJ. Phenylsulfonyl as a directing group for nitrile oxide cycloadditions and mCPBA epoxidations Tetrahedron Letters. 50: 5110-5112. DOI: 10.1016/J.Tetlet.2009.06.100 |
0.618 |
|
| 2008 |
Schwarzer C, Fischer H, Kim EJ, Barber KJ, Mills AD, Kurth MJ, Gruenert DC, Suh JH, Machen TE, Illek B. Oxidative stress caused by pyocyanin impairs CFTR Cl(-) transport in human bronchial epithelial cells. Free Radical Biology & Medicine. 45: 1653-62. PMID 18845244 DOI: 10.1016/J.Freeradbiomed.2008.09.011 |
0.679 |
|
| 2008 |
Yu GJ, Yoo CL, Yang B, Lodewyk MW, Meng L, El-Idreesy TT, Fettinger JC, Tantillo DJ, Verkman AS, Kurth MJ. Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy. Journal of Medicinal Chemistry. 51: 6044-54. PMID 18788728 DOI: 10.1021/Jm800533C |
0.786 |
|
| 2008 |
Carpenter RD, Fettinger JC, Lam KS, Kurth MJ. Asymmetric catalysis: resin-bound hydroxyprolylthreonine derivatives in enamine-mediated reactions. Angewandte Chemie (International Ed. in English). 47: 6407-10. PMID 18624312 DOI: 10.1002/Anie.200801811 |
0.35 |
|
| 2008 |
Al-Nakkash L, Springsteel MF, Kurth MJ, Nantz MH. Activation of CFTR by UCCF-029 and genistein. Bioorganic & Medicinal Chemistry Letters. 18: 3874-7. PMID 18595696 DOI: 10.1016/J.Bmcl.2008.06.051 |
0.771 |
|
| 2008 |
Milinkevich KA, Ye L, Kurth MJ. Synthesis of 5-(thiazol-5-yl)-4,5-dihydroisoxazoles from 3-chloropentane-2,4-dione. Journal of Combinatorial Chemistry. 10: 521-5. PMID 18505299 DOI: 10.1021/Cc800033M |
0.815 |
|
| 2008 |
Yoo CL, Yu GJ, Yang B, Robins LI, Verkman AS, Kurth MJ. 4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing. Bioorganic & Medicinal Chemistry Letters. 18: 2610-4. PMID 18394886 DOI: 10.1016/J.Bmcl.2008.03.037 |
0.78 |
|
| 2008 |
Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Shaw JT, Hinshaw JE, Green DR, Nunnari J. Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Developmental Cell. 14: 193-204. PMID 18267088 DOI: 10.1016/J.Devcel.2007.11.019 |
0.699 |
|
| 2008 |
Carpenter RD, DeBerdt PB, Holden JB, Milinkevich KA, Min T, Willenbring D, Fettinger JC, Tantillo DJ, Kurth MJ. Design and synthesis of propeller-shaped dispiroisoxazolinopiperidinochromanones. Journal of Combinatorial Chemistry. 10: 225-9. PMID 18232646 DOI: 10.1021/Cc700173X |
0.801 |
|
| 2008 |
Butler JD, Solano DM, Robins LI, Haddadin MJ, Kurth MJ. A facile synthesis of new 5H-indazolo[3,2-b]benzo[d]-1,3-oxazines via one-pot intramolecular Bis-heterocyclizations. The Journal of Organic Chemistry. 73: 234-40. PMID 18052193 DOI: 10.1021/Jo702067Z |
0.806 |
|
| 2008 |
Choung W, Lorsbach BA, Sparks TC, Ruiz JM, Kurth MJ. 4-(Isoxazol-3-yl)pyrimidines from pyrimidinyl nitrile oxides Synlett. 3036-3040. DOI: 10.1055/S-0028-1087346 |
0.325 |
|
| 2008 |
Milinkevich KA, Ye L, Kurth MJ. ChemInform Abstract: Synthesis of 5-(Thiazol-5-yl)-4,5-dihydroisoxazoles from 3-Chloropentane-2,4-dione. Cheminform. 39. DOI: 10.1002/chin.200848128 |
0.808 |
|
| 2007 |
Meng L, Fettinger JC, Kurth MJ. Intramolecular cycloaddition of azomethine ylides in the preparation of pyrrolidino[2',3':3,4]pyrrolidino[1,2- a]benzimidazoles. Organic Letters. 9: 5055-8. PMID 17973485 DOI: 10.1021/Ol702301N |
0.64 |
|
| 2007 |
Jeddeloh MR, Holden JB, Nouri DH, Kurth MJ. A library of 3-aryl-4,5-dihydroisoxazole-5-carboxamides. Journal of Combinatorial Chemistry. 9: 1041-5. PMID 17910514 DOI: 10.1021/Cc700117A |
0.39 |
|
| 2007 |
Robins LI, Kurth MJ. 1,3,5-triazine-based mass spectral tagging of one-bead one-compound libraries. Organic Letters. 9: 171-3. PMID 17217257 DOI: 10.1021/Ol062466D |
0.582 |
|
| 2007 |
Mills AD, Maloney P, Hassanein E, Haddadin MJ, Kurth MJ. Synthesis of a library of 2-alkyl-3-alkyloxy-2H-indazole-6-carboxamides. Journal of Combinatorial Chemistry. 9: 171-7. PMID 17206845 DOI: 10.1021/Cc060109O |
0.639 |
|
| 2007 |
Dixon SM, Milinkevich KA, Fujii J, Liu R, Yao N, Lam KS, Kurth MJ. A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis. Journal of Combinatorial Chemistry. 9: 143-57. PMID 17206843 DOI: 10.1021/Cc060090P |
0.806 |
|
| 2007 |
Robins LI, Fettinger JC, Tinti DS, Kurth MJ. Selective nucleophilic chemistry in the synthesis of 5-carbamoyl-3-sulfanylmethylisoxazole-4-carboxylic acids. Journal of Combinatorial Chemistry. 9: 139-42. PMID 17206842 DOI: 10.1021/Cc0601074 |
0.611 |
|
| 2007 |
Carpenter RD, Lam KS, Kurth MJ. Microwave-mediated heterocyclization to benzimidazo[2,1-b]quinazolin-12(5H)-ones. The Journal of Organic Chemistry. 72: 284-7. PMID 17194113 DOI: 10.1021/Jo0618066 |
0.354 |
|
| 2007 |
Varela MC, Dixon SM, Price MD, Merit JE, Berget PE, Shiraki S, Kurth MJ, Schore NE. Comparison of enantioselective reductions using bead and monolith 'disk' polymer formulations of CBS catalysts Tetrahedron. 63: 3334-3339. DOI: 10.1016/J.Tet.2007.02.048 |
0.732 |
|
| 2006 |
Dixon S, Ziebart KT, He Z, Jeddeloh M, Yoo CL, Wang X, Lehman A, Lam KS, Toney MD, Kurth MJ. Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design. Journal of Medicinal Chemistry. 49: 7413-26. PMID 17149871 DOI: 10.1021/Jm0609869 |
0.794 |
|
| 2006 |
Carpenter RD, Deberdt PB, Lam KS, Kurth MJ. Carbodiimide-based benzimidazole library method. Journal of Combinatorial Chemistry. 8: 907-14. PMID 17096580 DOI: 10.1021/Cc060106B |
0.35 |
|
| 2006 |
Robins LI, Dixon SM, Wilson DK, Kurth MJ. On-bead combinatorial techniques for the identification of selective aldose reductase inhibitors. Bioorganic & Medicinal Chemistry. 14: 7728-35. PMID 16931029 DOI: 10.1016/J.Bmc.2006.08.005 |
0.734 |
|
| 2006 |
Rieger R, Leung PS, Jeddeloh MR, Kurth MJ, Nantz MH, Lam KS, Barsky D, Ansari AA, Coppel RL, Mackay IR, Gershwin ME. Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. Journal of Autoimmunity. 27: 7-16. PMID 16876981 DOI: 10.1016/J.Jaut.2006.06.002 |
0.584 |
|
| 2006 |
Dixon SM, Li P, Liu R, Wolosker H, Lam KS, Kurth MJ, Toney MD. Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries. Journal of Medicinal Chemistry. 49: 2388-97. PMID 16610782 DOI: 10.1021/Jm050701C |
0.653 |
|
| 2006 |
Mills AD, Nazer MZ, Haddadin MJ, Kurth MJ. N,N-bond-forming heterocyclization: synthesis of 3-alkoxy-2H-indazoles. The Journal of Organic Chemistry. 71: 2687-9. PMID 16555821 DOI: 10.1021/Jo0524831 |
0.602 |
|
| 2006 |
Robins LI, Carpenter RD, Fettinger JC, Haddadin MJ, Tinti DS, Kurth MJ. Diazocinones: synthesis and conformational analysis. The Journal of Organic Chemistry. 71: 2480-5. PMID 16526800 DOI: 10.1021/Jo052577A |
0.577 |
|
| 2006 |
Suen YF, Robins L, Yang B, Verkman AS, Nantz MH, Kurth MJ. Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating. Bioorganic & Medicinal Chemistry Letters. 16: 537-40. PMID 16288863 DOI: 10.1016/J.Bmcl.2005.10.050 |
0.682 |
|
| 2006 |
Kurth M, Liu Y, Mills A. Solid-Phase Synthesis of Coumarins via ipso Substitution Reaction Synfacts. 2006: 0632-0632. DOI: 10.1055/s-2006-941798 |
0.707 |
|
| 2006 |
Liu Y, Mills AD, Kurth MJ. Solid phase synthesis of 3-(5-arylpyridin-2-yl)-4-hydroxycoumarins Tetrahedron Letters. 47: 1985-1988. DOI: 10.1016/J.Tetlet.2006.01.069 |
0.736 |
|
| 2006 |
Yoo CL, Olmstead MM, Tantillo DJ, Kurth MJ. Synthesis of 2H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides Tetrahedron Letters. 47: 477-481. DOI: 10.1016/J.Tetlet.2005.11.066 |
0.802 |
|
| 2005 |
Suen YF, Hope H, Nantz MH, Haddadin MJ, Kurth MJ. A novel route to fully substituted 1H-pyrazoles. The Journal of Organic Chemistry. 70: 8468-71. PMID 16209593 DOI: 10.1021/Jo051319A |
0.644 |
|
| 2005 |
Yoo CL, Fettinger JC, Kurth MJ. Stannous chloride in alcohol: a one-pot conversion of 2-nitro-N-arylbenzamides to 2,3-dihydro-1H-quinazoline-4-ones. The Journal of Organic Chemistry. 70: 6941-3. PMID 16095321 DOI: 10.1021/Jo050450F |
0.755 |
|
| 2005 |
Dixon S, Robins L, Elling RA, Liu R, Lam KS, Wilson DK, Kurth MJ. Discovery of selective aldo-keto reductase ligands--an on-bead assay strategy. Bioorganic & Medicinal Chemistry Letters. 15: 2938-42. PMID 15911284 DOI: 10.1016/J.Bmcl.2005.03.010 |
0.713 |
|
| 2005 |
Amano K, Leung PS, Rieger R, Quan C, Wang X, Marik J, Suen YF, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Matsuura E, Coppel RL, Gershwin ME. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. Journal of Immunology (Baltimore, Md. : 1950). 174: 5874-83. PMID 15845458 DOI: 10.4049/Jimmunol.174.9.5874 |
0.661 |
|
| 2005 |
Pedemonte N, Sonawane ND, Taddei A, Hu J, Zegarra-Moran O, Suen YF, Robins LI, Dicus CW, Willenbring D, Nantz MH, Kurth MJ, Galietta LJ, Verkman AS. Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Molecular Pharmacology. 67: 1797-807. PMID 15722457 DOI: 10.1124/Mol.105.010959 |
0.681 |
|
| 2005 |
Kurth MJ, Olmstead MM, Haddadin MJ. Claimed 2,1-benzisoxazoles are indazalones. The Journal of Organic Chemistry. 70: 1060-2. PMID 15675871 DOI: 10.1021/Jo048153I |
0.34 |
|
| 2005 |
Wang X, Dixon S, Kurth MJ, Lam KS. Synthesis of 1,4-Disubstituted-6-nitro-3,4-dihydro-1H-quinoline-2-ones Synfacts. 2005: 354-354. DOI: 10.1055/S-2005-921619 |
0.685 |
|
| 2005 |
Dixon S, Wang X, Lam KS, Kurth MJ. Solid-phase synthesis of quinoxaline, thiazine, and oxazine analogs through a benzyne intermediate Tetrahedron Letters. 46: 7443-7446. DOI: 10.1016/J.Tetlet.2005.08.061 |
0.683 |
|
| 2005 |
Wang X, Dixon S, Yao N, Kurth MJ, Lam KS. Microwave assisted DIC-promoted intramolecular cyclization for solid phase synthesis of trisubstituted imidazolidinones and pyrimidinones Tetrahedron Letters. 46: 5747-5750. DOI: 10.1016/J.Tetlet.2005.06.041 |
0.692 |
|
| 2005 |
Wang X, Dixon S, Kurth MJ, Lam KS. Traceless solid-phase synthesis of 1,4-disubstituted-6-nitro-3,4-dihydro- 1H-quinoline-2-ones Tetrahedron Letters. 46: 5361-5364. DOI: 10.1016/J.Tetlet.2005.06.012 |
0.693 |
|
| 2005 |
Wang X, Song A, Dixon S, Kurth MJ, Lam KS. Facile solid phase synthesis of 1,2-disubstituted-6-nitro-1,4- dihydroquinazolines using a tetrafunctional scaffold Tetrahedron Letters. 46: 427-430. DOI: 10.1016/J.Tetlet.2004.11.095 |
0.694 |
|
| 2004 |
Hwang SH, Lehman A, Cong X, Olmstead MM, Lam KS, Lebrilla CB, Kurth MJ. OBOC small-molecule combinatorial library encoded by halogenated mass-tags. Organic Letters. 6: 3829-32. PMID 15469360 DOI: 10.1021/Ol048408E |
0.476 |
|
| 2004 |
Amano K, Leung PS, Xu Q, Marik J, Quan C, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Coppel RL, Gershwin ME. Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. Journal of Immunology (Baltimore, Md. : 1950). 172: 6444-52. PMID 15128836 DOI: 10.4049/Jimmunol.172.10.6444 |
0.645 |
|
| 2004 |
Quan C, Kurth M. Solid-phase synthesis of 5-isoxazol-4-yl-[1,2,4]oxadiazoles. The Journal of Organic Chemistry. 69: 1470-4. PMID 14986998 DOI: 10.1021/Jo0352124 |
0.576 |
|
| 2004 |
Hwang SH, Olmstead MM, Kurth MJ. Solid-phase synthesis of an isoxazolinopyrrole library. Journal of Combinatorial Chemistry. 6: 142-8. PMID 14714998 DOI: 10.1021/Cc034023W |
0.537 |
|
| 2003 |
Bruggraber SF, Leung PS, Amano K, Quan C, Kurth MJ, Nantz MH, Benson GD, Van de Water J, Luketic V, Roche TE, Ansari AA, Coppel RL, Gershwin ME. Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis. Gastroenterology. 125: 1705-13. PMID 14724823 DOI: 10.1053/J.Gastro.2003.09.034 |
0.653 |
|
| 2003 |
Selmi C, Balkwill DL, Invernizzi P, Ansari AA, Coppel RL, Podda M, Leung PS, Kenny TP, Van De Water J, Nantz MH, Kurth MJ, Gershwin ME. Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. Hepatology (Baltimore, Md.). 38: 1250-7. PMID 14578864 DOI: 10.1053/Jhep.2003.50446 |
0.545 |
|
| 2003 |
Springsteel MF, Galietta LJ, Ma T, By K, Berger GO, Yang H, Dicus CW, Choung W, Quan C, Shelat AA, Guy RK, Verkman AS, Kurth MJ, Nantz MH. Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. Bioorganic & Medicinal Chemistry. 11: 4113-20. PMID 12927873 DOI: 10.1016/S0968-0896(03)00435-8 |
0.788 |
|
| 2003 |
Sammelson RE, Ma T, Galietta LJ, Verkman AS, Kurth MJ. 3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators. Bioorganic & Medicinal Chemistry Letters. 13: 2509-12. PMID 12852954 DOI: 10.1016/S0960-894X(03)00482-7 |
0.71 |
|
| 2003 |
Leung PS, Quan C, Park O, Van de Water J, Kurth MJ, Nantz MH, Ansari AA, Coppel RL, Lam KS, Gershwin ME. Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. Journal of Immunology (Baltimore, Md. : 1950). 170: 5326-32. PMID 12734383 DOI: 10.4049/Jimmunol.170.10.5326 |
0.644 |
|
| 2003 |
Caci E, Folli C, Zegarra-Moran O, Ma T, Springsteel MF, Sammelson RE, Nantz MH, Kurth MJ, Verkman AS, Galietta LJ. CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L180-8. PMID 12651632 DOI: 10.1152/Ajplung.00351.2002 |
0.775 |
|
| 2003 |
Park KH, Olmstead MM, Kurth MJ. Synthesis of isoxazoline-substituted symmetrical diketopiperazines Synlett. 1267-1270. DOI: 10.1055/S-2003-40333 |
0.584 |
|
| 2003 |
Price MD, Radosevich JL, Kurth MJ, Schore NE. Customized solid supports for small-molecule synthesis: Effects of crosslinking structure and degree Reactive and Functional Polymers. 55: 131-137. DOI: 10.1016/S1381-5148(02)00222-5 |
0.61 |
|
| 2003 |
BRUGGRABER S, LEUNG P, AMANO K, QUAN C, KURTH M, NANTZ M, BENSON G, VANDEWATER J, LUKETIC V, ANSARI A. 741 Autoantibodies to lipoic acid and to conjugated lipoate are uniquely found in primary biliary cirrhosis Hepatology. 38: 517-517. DOI: 10.1016/S0270-9139(03)80783-8 |
0.545 |
|
| 2003 |
AMANO K, LEUNG P, XU Q, MARIK J, QUAN C, KURTH M, NANTZ M, LAM K, ZENIYA M, ANSARI A. 102 Use of a conjugated peptide microarray for ultra fine mapping of antimitochondrial antibodies Hepatology. 38: 205-205. DOI: 10.1016/S0270-9139(03)80145-3 |
0.513 |
|
| 2003 |
LEUNG P, MATSUMURA S, PARK O, VANDEWATER J, QUAN C, KURTH M, NANTZ M, ANSARI A, COPPEL R, GERSHWIN M. 97 Induction of primary biliary cirrhosis in guinea pigs following immunization with a chemical xenobiotic Hepatology. 38: 203-203. DOI: 10.1016/S0270-9139(03)80140-4 |
0.523 |
|
| 2002 |
Price MD, Sui JK, Kurth MJ, Schore NE. Oxazaborolidines as functional monomers: ketone reduction using polymer-supported Corey, Bakshi, and Shibata catalysts. The Journal of Organic Chemistry. 67: 8086-9. PMID 12423136 DOI: 10.1021/Jo026132N |
0.586 |
|
| 2002 |
Price MD, Kurth MJ, Schore NE. Comparison of solid-phase and solution-phase chiral auxiliaries in the alkylation/iodolactonization sequence to gamma-butyrolactones. The Journal of Organic Chemistry. 67: 7769-73. PMID 12398501 DOI: 10.1021/Jo0260692 |
0.589 |
|
| 2002 |
Hwang SH, Kurth MJ. Versatile "traceless" sulfone linker for SPOS: preparation of isoxazolinopyrrole 2-carboxylates. The Journal of Organic Chemistry. 67: 6564-7. PMID 12201785 DOI: 10.1021/Jo016377K |
0.551 |
|
| 2002 |
Kwon HJ, Smith WC, Scharon AJ, Hwang SH, Kurth MJ, Shen B. C-O bond formation by polyketide synthases. Science (New York, N.Y.). 297: 1327-30. PMID 12193782 DOI: 10.1126/Science.1073175 |
0.397 |
|
| 2002 |
Cheng WC, Liu Y, Wong M, Olmstead MM, Lam KS, Kurth MJ. Stereoselective synthesis of unnatural spiroisoxazolinoproline-based amino acids and derivatives. The Journal of Organic Chemistry. 67: 5673-7. PMID 12153267 DOI: 10.1021/Jo025611J |
0.687 |
|
| 2002 |
Cheng WC, Kurth MJ. The sulfone linker in solid-phase synthesis: preparation of 3,5-disubstituted cyclopent-2-enones. The Journal of Organic Chemistry. 67: 4387-91. PMID 12076132 DOI: 10.1021/Jo0256843 |
0.557 |
|
| 2002 |
Huang KS, Haddadin MJ, Kurth MJ. Imidazopyridinium and pyridopyrimidium bromides: synthesis and hydrolysis. The Journal of Organic Chemistry. 67: 2382-5. PMID 11925262 DOI: 10.1021/Jo016387L |
0.348 |
|
| 2002 |
Liu Y, Kurth MJ. Ipso substitution as a route to benzo[c]quinolizines and 4-hydroxycoumarins. The Journal of Organic Chemistry. 67: 2082-6. PMID 11925212 DOI: 10.1021/Jo0161126 |
0.623 |
|
| 2002 |
Cheng WC, Wong M, Olmstead MM, Kurth MJ. Solid-phase synthesis of novel isoxazolocyclobutanones and isoxazolinocyclobutenones. Organic Letters. 4: 741-4. PMID 11869116 DOI: 10.1021/Ol017194N |
0.563 |
|
| 2002 |
Sammelson RE, Gurusinghe CD, Kurth JM, Olmstead MM, Kurth MJ. Synthesis of spiro-fused (C5)-isoxazolino-(C4)-pyrazolones (1-oxa-2,7,8-triazaspiro[4,4]-2,8-dien-6-ones) via 1,3-dipolar cycloaddition and cycloelimination. The Journal of Organic Chemistry. 67: 876-82. PMID 11856032 DOI: 10.1021/Jo010895D |
0.709 |
|
| 2002 |
Gong YD, Kim SK, Yoo Se, Kurth MJ. Epimerization in intramolecular carbanilide cyclization to hydantoins: A computational study Bulletin of the Chemical Society of Japan. 75: 2477-2480. DOI: 10.1246/Bcsj.75.2477 |
0.319 |
|
| 2002 |
Reynoso-Paz CM, Olmstead MM, Kurth MJ, Schore NE. A solution phase catalyst for an enantioselective Diels–Alder reaction Acta Crystallographica Section E Structure Reports Online. 58: m310-m312. DOI: 10.1107/S1600536802009303 |
0.602 |
|
| 2002 |
Cheng WC, Kurth MJ. The zincke reaction. A review Organic Preparations and Procedures International. 34: 585-608. DOI: 10.1080/00304940209355784 |
0.5 |
|
| 2002 |
Huang L, Olmstead MM, Kurth MJ. A concise synthesis of chiral 3-hydroxymethyl-5-isopropyl morpholines from valinol Organic Preparations and Procedures International. 34: 511-514. DOI: 10.1080/00304940209355773 |
0.34 |
|
| 2002 |
Price MD, Kurth MJ, Schore NE. Comparison of solid-phase and solution-phase chiral auxiliaries in the alkylation/iodolactonization sequence to γ-butyrolactones Journal of Organic Chemistry. 67: 7769-7773. DOI: 10.1021/jo0260692 |
0.519 |
|
| 2002 |
Kim P, Tsuruda JM, Olmstead MM, Eisenberg S, Kurth MJ. An intramolecular Diels-Alder route to novel tetracyclic benzo[b]thiophene derivatives Tetrahedron Letters. 43: 3963-3966. DOI: 10.1016/S0040-4039(02)00565-8 |
0.589 |
|
| 2002 |
Cheng WC, Lin CC, Kurth MJ. Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones Tetrahedron Letters. 43: 2967-2970. DOI: 10.1016/S0040-4039(02)00423-9 |
0.52 |
|
| 2002 |
Hwang SH, Kurth MJ. 1,3-Dipolar cycloaddition of nitrile oxides to 1-phenylsulfonyl-1,3-butadienes: Synthesis of 3-(4,5-dihydroisoxazol-5-yl)pyrroles Tetrahedron Letters. 43: 53-56. DOI: 10.1016/S0040-4039(01)02069-X |
0.561 |
|
| 2002 |
Park KH, Kurth MJ. Cyclic amino acid derivatives Tetrahedron. 58: 8629-8659. DOI: 10.1016/S0040-4020(02)00989-4 |
0.532 |
|
| 2002 |
Fan XD, Hsien YL, Kurth MJ, Krochta JM. Synthesis and characterization of lactose based resorcinol resin Journal of Applied Polymer Science. 86: 2581-2585. DOI: 10.1002/App.11216 |
0.33 |
|
| 2001 |
Sammelson RE, Kurth MJ. Carbon-carbon bond-forming solid-phase reactions. Part II. Chemical Reviews. 101: 137-202. PMID 11712191 DOI: 10.1021/Cr000086E |
0.671 |
|
| 2001 |
Long SA, Quan C, Van de Water J, Nantz MH, Kurth MJ, Barsky D, Colvin ME, Lam KS, Coppel RL, Ansari A, Gershwin ME. Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 2956-63. PMID 11509645 DOI: 10.4049/Jimmunol.167.5.2956 |
0.665 |
|
| 2001 |
Cheng WC, Olmstead MM, Kurth MJ. Vinyl sulfones in solid-phase synthesis: preparation of 4,5,6,7-tetrahydroisoindole derivatives. The Journal of Organic Chemistry. 66: 5528-33. PMID 11485478 DOI: 10.1021/Jo0156823 |
0.548 |
|
| 2001 |
Huang KS, Haddadin MJ, Olmstead MM, Kurth MJ. Synthesis and reactions of some heterocyclic azacyanines. The Journal of Organic Chemistry. 66: 1310-5. PMID 11312961 DOI: 10.1021/Jo001484K |
0.406 |
|
| 2001 |
Wu J, Lizarzaburu ME, Kurth MJ, Liu L, Wege H, Zern MA, Nantz MH. Cationic lipid polymerization as a novel approach for constructing new DNA delivery agents. Bioconjugate Chemistry. 12: 251-7. PMID 11312686 DOI: 10.1021/Bc000097E |
0.771 |
|
| 2001 |
Park KH, Ehrler J, Spoerri H, Kurth MJ. Preparation of a 990-member chemical compound library of hydantoin- and isoxazoline-containing heterocycles using multipin technology. Journal of Combinatorial Chemistry. 3: 171-6. PMID 11300857 DOI: 10.1021/Cc0000702 |
0.61 |
|
| 2001 |
Galietta LJ, Springsteel MF, Eda M, Niedzinski EJ, By K, Haddadin MJ, Kurth MJ, Nantz MH, Verkman AS. Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. The Journal of Biological Chemistry. 276: 19723-8. PMID 11262417 DOI: 10.1074/Jbc.M101892200 |
0.793 |
|
| 2001 |
Reynoso-Paz M, Olmstead MM, Kurth MJ, Schore NE. An enantiopure bicyclic pentasubstituted piperidine Acta Crystallographica Section E Structure Reports Online. 57: o1177-o1178. DOI: 10.1107/S1600536801019055 |
0.564 |
|
| 2001 |
Alonso C, Olmstead MM, Nantz MH, Kurth MJ. Competitive intramolecular nucleophilic aromatic substitution: A new route to coumarins Chemical Communications. 639-640. DOI: 10.1039/B009172N |
0.617 |
|
| 2001 |
Sammelson RE, Kurth MJ. Oxidation-Cope elimination: A REM-resin cleavage protocol for the solid-phase synthesis of hydroxylamines Tetrahedron Letters. 42: 3419-3422. DOI: 10.1016/S0040-4039(01)00477-4 |
0.709 |
|
| 2001 |
Eda M, Kurth MJ. Solid-phase Zincke route to pyridinium, tetrahydropyridine, and piperidine derivatives: Vesamicol analogs Tetrahedron Letters. 42: 2063-2068. DOI: 10.1016/S0040-4039(00)02351-0 |
0.339 |
|
| 2001 |
Park KH, Kurth TM, Olmstead MM, Kurth MJ. Regio- and diastereoselective synthesis of cyclic amino esters Tetrahedron Letters. 42: 991-992. DOI: 10.1016/S0040-4039(00)02217-6 |
0.57 |
|
| 2001 |
By K, Kelly PA, Kurth MJ, Olmstead MM, Nantz MH. Synthesis of a C(4)-C(9) eleutheside template from D-glucal Tetrahedron. 57: 1183-1187. DOI: 10.1016/S0040-4020(00)01117-0 |
0.585 |
|
| 2001 |
Sammelson RE, Kurth MJ. ChemInform Abstract: Carbon-Carbon Bond-Forming Solid-Phase Reactions. Part 2. Cheminform. 32: no-no. DOI: 10.1002/chin.200110289 |
0.65 |
|
| 2000 |
Sammelson RE, Olmstead MM, Haddadin MJ, Kurth MJ. 1,2,4,5-Tetrazines as oxidant and reactant with DBU: An unexpected formation of a novel fused tetraheterocyclic azepine The Journal of Organic Chemistry. 65: 9265-7. PMID 11149886 DOI: 10.1021/Jo001363K |
0.683 |
|
| 2000 |
Illek B, Lizarzaburu ME, Lee V, Nantz MH, Kurth MJ, Fischer H. Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin. American Journal of Physiology. Cell Physiology. 279: C1838-46. PMID 11078699 DOI: 10.1152/Ajpcell.2000.279.6.C1838 |
0.772 |
|
| 2000 |
Eda M, Kurth MJ, Nantz MH. The solid-phase Zincke reaction: preparation of omega-hydroxy pyridinium salts in the search for CFTR activation. The Journal of Organic Chemistry. 65: 5131-5. PMID 10993337 DOI: 10.1021/Jo0001636 |
0.636 |
|
| 2000 |
Kim P, Nantz MH, Kurth MJ, Olmstead MM. Intramolecular Diels-Alder Reactions of Decatrienoates: Remote Stereocontrol and Conformational Activation(1). Organic Letters. 2: 1831-1834. PMID 10891169 DOI: 10.1021/Ol005886Q |
0.707 |
|
| 2000 |
Park KH, Kurth MJ. Diastereoselective synthesis of hydantoin- and isoxazoline-substituted dispirocyclobutanoids. The Journal of Organic Chemistry. 65: 3520-4. PMID 10843640 DOI: 10.1021/Jo000152C |
0.566 |
|
| 2000 |
Huang KS, Lee EH, Olmstead MM, Kurth MJ. Sequential 1,3-dipolar cycloadditions in the synthesis of bis-isoxazolo substituted piperidinones The Journal of Organic Chemistry. 65: 499-503. PMID 10813963 DOI: 10.1021/Jo991418M |
0.413 |
|
| 2000 |
Sammelson RE, Miller RB, Kurth MJ. Linear tetraheterocycles composed of both bidentate diisoxazole and bidentate isoxazole--furyl/thienyl/pyridyl motifs The Journal of Organic Chemistry. 65: 2225-8. PMID 10774051 DOI: 10.1021/Jo991551E |
0.653 |
|
| 2000 |
Park KH, Kurth MJ. Cyclo-elimination release strategies applied to solid-phase organic synthesis in drug discovery Drugs of the Future. 25: 1265-1294. DOI: 10.1358/dof.2000.025.12.616456 |
0.446 |
|
| 2000 |
Park KH, Kurth MJ. Solid-phase synthesis of novel achiral hydantoin- and isoxazoline-substituted dispirocyclobutanoids Chemical Communications. 1835-1836. DOI: 10.1039/B004033I |
0.585 |
|
| 2000 |
Sammelson RE, Miller RB, Kurth MJ. Linear tetraheterocycles composed of both bidentate diisoxazole and bidentate isoxazole-furyl/thienyl/pyridyl/motifs Journal of Organic Chemistry. 65: 2225-2228. DOI: 10.1021/jo991551e |
0.627 |
|
| 2000 |
Park KH, Kurth MJ. Hydantoin formation by cyclo-elimination: Reactivity difference between Merrifield- and Wang-derived resins Tetrahedron Letters. 41: 7409-7413. DOI: 10.1016/S0040-4039(00)01073-X |
0.538 |
|
| 2000 |
Alonso C, Nantz MH, Kurth MJ. β-Dimethylphenylsilylethyl esters: A linker for solid-phase chemistry Tetrahedron Letters. 41: 5617-5622. DOI: 10.1016/S0040-4039(00)00909-6 |
0.587 |
|
| 2000 |
Haddadin MJ, Kurth MJ, Olmstead MM. One-step synthesis of new heterocyclic azacyanines Tetrahedron Letters. 41: 5613-5616. DOI: 10.1016/S0040-4039(00)00908-4 |
0.425 |
|
| 2000 |
Kim P, Olmstead MM, Nantz MH, Kurth MJ. Knoevenagel condensations of β-hemiacetyl esters Tetrahedron Letters. 41: 4029-4032. DOI: 10.1016/S0040-4039(00)00581-5 |
0.665 |
|
| 2000 |
Kantorowski EJ, Kurth MJ. Expansion to seven-membered rings Tetrahedron. 56: 4317-4353. DOI: 10.1016/S0040-4020(00)00218-0 |
0.757 |
|
| 1999 |
Lizarzaburu ME, Jones RM, Nantz MH, Kurth MJ. Multi-gram synthesis of dimyristoyl pentaerythritol Organic Preparations and Procedures International. 31: 440-442. DOI: 10.1080/00304949909355735 |
0.791 |
|
| 1999 |
Zhou WJ, Kurth MJ, Hsieh YL, Krochta JM. Synthesis and characterization of new styrene main-chain polymer with pendant lactose moiety through urea linkage Macromolecules. 32: 5507-5513. DOI: 10.1021/Ma990397V |
0.323 |
|
| 1999 |
Park KH, Kurth MJ. Solid-phase synthesis of novel heterocycles containing thiohydantoin and isoxazole rings Journal of Organic Chemistry. 64: 9297-9300. DOI: 10.1021/Jo991166P |
0.563 |
|
| 1999 |
Cheng WC, Halm C, Evarts JB, Olmstead MM, Kurth MJ. Allylic sulfones in solid-phase synthesis: Preparation of cyclobutylidenes Journal of Organic Chemistry. 64: 8557-8562. DOI: 10.1021/Jo990954B |
0.584 |
|
| 1999 |
Kantorowski EJ, Eisenberg SWE, Fink WH, Kurth MJ. Six- vs Seven-Membered Ring Formation from the 1-Bicyclo[4.1.0]heptanylmethyl Radical: Synthetic and ab Initio Studies† The Journal of Organic Chemistry. 64: 570-580. DOI: 10.1021/Jo981708N |
0.754 |
|
| 1999 |
Lizarzaburu ME, Kurth MJ, Nantz MH. A versatile synthesis of tetraester polyamine lipids for gene transfection Tetrahedron Letters. 40: 8985-8988. DOI: 10.1016/S0040-4039(99)01934-6 |
0.793 |
|
| 1999 |
Park KH, Kurth MJ. An uncatalyzed cyclo-elimination process for the release of N3- alkylated hydantoins from solid-phase: Synthesis of novel isoxazoloimidazolidinediones Tetrahedron Letters. 40: 5841-5844. DOI: 10.1016/S0040-4039(99)01145-4 |
0.551 |
|
| 1999 |
Kizer DE, Miller R, Kurth MJ. Fused pyrazolo heterocycles: intramolecular [3+2]-nitrile oxide cycloadditions applied to syntheses of pyrazolo [3,4-g] [2,1] dihydrobenzoisoxazol (in) es Tetrahedron Letters. 40: 3535-3538. DOI: 10.1016/S0040-4039(99)00559-6 |
0.326 |
|
| 1998 |
Halm C, Kurth MJ. Functionalized Cross-Linked Copolymers: A "C -Symmetric" Solid-Phase Catalyst for Enantioselective Reactions. Angewandte Chemie (International Ed. in English). 37: 510-512. PMID 29711160 DOI: 10.1002/(Sici)1521-3773(19980302)37:4<510::Aid-Anie510>3.0.Co;2-9 |
0.315 |
|
| 1998 |
Park KH, Olmstead MM, Kurth MJ. Diastereoselective Synthesis of Cyclopentanoids with Hydantoin and Isoxazoline Substituents. The Journal of Organic Chemistry. 63: 113-117. PMID 11674050 DOI: 10.1021/Jo9714831 |
0.59 |
|
| 1998 |
Park K, Abbate E, Olmstead MM, Kurth MJ, Najdi S. Solution- and solid-phase synthesis of novel hydantoin and isoxazoline-containing heterocycles Chemical Communications. 1679-1680. DOI: 10.1039/A803400A |
0.534 |
|
| 1998 |
Park K, Olmstead MM, Kurth MJ. Diastereoselective Solid-Phase Synthesis of Novel Hydantoin- and Isoxazoline-Containing Heterocycles The Journal of Organic Chemistry. 63: 6579-6585. DOI: 10.1021/Jo9807161 |
0.313 |
|
| 1998 |
Gong Y, Sohn H, Kurth MJ. Microwave-Mediated Intramolecular Carbanilide Cyclization to Hydantoins Employing Barium Hydroxide Catalysis The Journal of Organic Chemistry. 63: 4854-4856. DOI: 10.1021/Jo980419W |
0.396 |
|
| 1998 |
Kantorowski EJ, Brown SP, Kurth MJ. Use of Diisocyanates for in Situ Preparation of Nitrile Oxides: Preparation of Isoxazoles and Isoxazolines The Journal of Organic Chemistry. 63: 5272-5274. DOI: 10.1021/Jo980411M |
0.764 |
|
| 1998 |
Gong Y, Najdi S, Olmstead MM, Kurth MJ. Solid-Phase Synthesis: Intramolecular Azomethine Ylide Cycloaddition (→Proline) and Carbanilide Cyclization (→Hydantoin) Reactions The Journal of Organic Chemistry. 63: 3081-3086. DOI: 10.1021/Jo9800210 |
0.384 |
|
| 1998 |
Lorsbach BA, Bagdanoff JT, Miller RB, Kurth MJ. Isoxazolinoisoquinoline Heterocycles via Solid-Phase Reissert and Suzuki Reactions The Journal of Organic Chemistry. 63: 2244-2250. DOI: 10.1021/Jo9720142 |
0.344 |
|
| 1998 |
Gong Y, Kurth MJ. Microwave-promoted reactions: Intramolecular carbanilide cyclization to hydantoins employing barium hydroxide catalyst Tetrahedron Letters. 39: 3379-3382. DOI: 10.1016/S0040-4039(98)00497-3 |
0.363 |
|
| 1998 |
Kantorowski EJ, Borhan B, Nazarian S, Kurth MJ. Cyclopropylcarbinyl radical-mediated ring expansion to seven-membered carbocycles Tetrahedron Letters. 39: 2483-2486. DOI: 10.1016/S0040-4039(98)00311-6 |
0.785 |
|
| 1998 |
Najdi S, Park KH, Olmstead MM, Kurth MJ. Synthesis of hexahydro-1H-pyrrolo[1,2-c]imidazole derivatives by sequential azomethine ylide cycloaddition and urea cyclization reactions Tetrahedron Letters. 39: 1685-1688. DOI: 10.1016/S0040-4039(98)00125-7 |
0.588 |
|
| 1998 |
Montierth JM, DeMario DR, Kurth MJ, Schore NE. The polymer-supported Cadiot-Chodkiewicz coupling of acetylenes to produce unsymmetrical diynes Tetrahedron. 54: 11741-11748. DOI: 10.1016/S0040-4020(98)83035-4 |
0.58 |
|
| 1997 |
Kantorowski EJ, Kurth MJ. Dipolar cycloadditions in solid-phase organic synthesis (SPOS). Molecular Diversity. 2: 207-16. PMID 9249756 DOI: 10.1007/Bf01715636 |
0.78 |
|
| 1997 |
Zhou W, Wilson ME, Kurth MJ, Hsieh Y, Krochta JM, Shoemaker CF. Synthesis and Properties of a Novel Water-Soluble Lactose-Containing Polymer and Its Cross-Linked Hydrogel Macromolecules. 30: 7063-7068. DOI: 10.1021/Ma970873M |
0.305 |
|
| 1997 |
Kantorowski EJ, Kurth MJ. Solid-Phase Synthesis of Isoxazoles and Isoxazolines: En Route to a New Class of Ionophores The Journal of Organic Chemistry. 62: 6797-6803. DOI: 10.1021/Jo970712G |
0.79 |
|
| 1997 |
Halm C, Evarts J, Kurth MJ. A new attachment/cleavage strategy: Polymer-bound allylic sulfones in a solid-phase route to trisubstituted olefins Tetrahedron Letters. 38: 7709-7712. DOI: 10.1016/S0040-4039(97)10062-4 |
0.363 |
|
| 1997 |
Spitzer JL, Kurth MJ, Schore NE, Najdi SD. Polymer-supported synthesis as a tool for improving chemoselectivity: Pauson-Khand reaction Tetrahedron. 53: 6791-6808. DOI: 10.1016/S0040-4020(97)00386-4 |
0.603 |
|
| 1997 |
Chen C, Ahlberg Randall LA, Bryan Miller R, Daniel Jones A, Kurth MJ. The solid-phase combinatorial synthesis of β-thioketones Tetrahedron. 53: 6595-6609. DOI: 10.1016/S0040-4020(97)00219-6 |
0.357 |
|
| 1996 |
Kurth MJ, Ahlberg Randall LA, Takenouchi K. Solid-Phase Combinatorial Synthesis of Polyisoxazolines: A Two-Reaction Iterative Protocol. The Journal of Organic Chemistry. 61: 8755-8761. PMID 11667849 DOI: 10.1021/Jo961730L |
0.373 |
|
| 1996 |
Lorsbach BA, Miller RB, Kurth MJ. Reissert-Based "Traceless" Solid-Phase Synthesis: Isoquinoline, and Isoxazoline-Containing Heterocycles. The Journal of Organic Chemistry. 61: 8716-8717. PMID 11667837 DOI: 10.1021/Jo961916K |
0.323 |
|
| 1996 |
Eisenberg SW, Chen C, Wu J, Lebrilla C, Kurth MJ. Cyclic oligolides via acylketene mediated lactonization: Synthesis and characterization Tetrahedron Letters. 37: 7683-7686. DOI: 10.1016/0040-4039(96)01757-1 |
0.385 |
|
| 1996 |
Wilson ME, Hu M, Kurth MJ, Hsieh Y, Krochta JM. Preparation and characterization of lactitol-based poly(ether polyol)s for rigid polyurethane foam Journal of Applied Polymer Science. 59: 1759-1768. DOI: 10.1002/(Sici)1097-4628(19960314)59:11<1759::Aid-App12>3.0.Co;2-P |
0.318 |
|
| 1995 |
Borhan B, Mebrahtu T, Nazarian S, Kurth MJ, Hammock BD. Improved radiolabeled substrates for soluble epoxide hydrolase. Analytical Biochemistry. 231: 188-200. PMID 8678300 DOI: 10.1006/Abio.1995.1520 |
0.637 |
|
| 1995 |
Borhan B, Ko Y, Mackay C, Wilson BW, Kurth MJ, Hammock BD. Development of surrogate substrates for neuropathy target esterase. Biochimica Et Biophysica Acta. 1250: 171-82. PMID 7632722 DOI: 10.1016/0167-4838(95)00058-3 |
0.623 |
|
| 1995 |
Borhan B, Jones AD, Pinot F, Grant DF, Kurth MJ, Hammock BD. Mechanism of soluble epoxide hydrolase. Formation of an alpha-hydroxy ester-enzyme intermediate through Asp-333. The Journal of Biological Chemistry. 270: 26923-30. PMID 7592938 DOI: 10.1074/Jbc.270.45.26923 |
0.642 |
|
| 1995 |
Borhan B, Wilson JA, Gasch MJ, Ko Y, Kurth DM, Kurth MJ. Suspension copolymerization as a route to trityl-functionalized polystyrene polymers The Journal of Organic Chemistry. 60: 7375-7378. DOI: 10.1021/Jo00127A057 |
0.531 |
|
| 1995 |
Beebe X, Chiappari CL, Olmstead MM, Kurth MJ, Schore NE. Polymer-Supported Synthesis of Cyclic Ethers: Electrophilic Cyclization of Tetrahydrofuroisoxazolines The Journal of Organic Chemistry. 60: 4204-4212. DOI: 10.1021/Jo00118A042 |
0.61 |
|
| 1995 |
Beebe X, Schore NE, Kurth MJ. Polymer-Supported Synthesis of Cyclic Ethers: Electrophilic Cyclization of Isoxazolines The Journal of Organic Chemistry. 60: 4196-4203. DOI: 10.1021/Jo00118A041 |
0.61 |
|
| 1994 |
Moon H, Eisenberg SWE, Wilson ME, Schore NE, Kurth MJ. Preparation of Nonracemic 3,5-Disubstituted-.gamma.-butyrolactones: An Effective Sequent Auxiliary for Amide Alkylation and Iodolactonization The Journal of Organic Chemistry. 59: 6504-6505. DOI: 10.1021/Jo00101A002 |
0.606 |
|
| 1994 |
Kurth MJ, Ahlberg Randall LA, Chen C, Melander C, Miller RB, McAlister K, Reitz G, Kang R, Nakatsu T, Green C. Library-Based Lead Compound Discovery: Antioxidants by an Analogous Synthesis/Deconvolutive Assay Strategy The Journal of Organic Chemistry. 59: 5862-5864. DOI: 10.1021/Jo00099A008 |
0.35 |
|
| 1994 |
Borhan B, Nazarian S, Stocking EM, Hammock BD, Kurth MJ. An Efficient Preparation of 18O-Labeled Epoxides The Journal of Organic Chemistry. 59: 4316-4318. DOI: 10.1021/Jo00094A054 |
0.385 |
|
| 1994 |
Duffy JL, Kurth MJ. A Novel Intramolecular Silyl Nitronate Cycloaddition Route to Dihydrofuraldehydes and Dihydropyranaldehydes The Journal of Organic Chemistry. 59: 3783-3785. DOI: 10.1021/Jo00093A009 |
0.303 |
|
| 1994 |
McKew JC, Olmstead MM, Kurth MJ. Doubly Diastereoselective Iodolactonizations: Olefin and Face Selectivity in Nona-2,7-diene-5-carboxylic Acid Cyclizations The Journal of Organic Chemistry. 59: 3389-3393. DOI: 10.1021/Jo00091A029 |
0.305 |
|
| 1994 |
Chen C, Randall LAA, Miller RB, Jones AD, Kurth MJ. "Analogous" Organic Synthesis of Small-Compound Libraries: Validation of Combinatorial Chemistry in Small-Molecule Synthesis Journal of the American Chemical Society. 116: 2661-2662. DOI: 10.1021/Ja00085A073 |
0.346 |
|
| 1994 |
Moon Hs, Schore NE, Kurth MJ. A polymer-supported C2-symmetric chiral auxiliary: Preparation of non-racemic 3,5-disubstituted-γ-butyrolactones Tetrahedron Letters. 35: 8915-8918. DOI: 10.1016/0040-4039(94)88388-2 |
0.599 |
|
| 1993 |
Marco MP, Nasiri M, Kurth MJ, Hammock BD. Enzyme-linked immunosorbent assay for the specific detection of the mercapturic acid metabolites of naphthalene. Chemical Research in Toxicology. 6: 284-93. PMID 8318650 DOI: 10.1021/Tx00033A006 |
0.441 |
|
| 1993 |
Marco MP, Hammock BD, Kurth MJ. Hapten design and development of an ELISA (enzyme-linked immunosorbent assay) for the detection of the mercapturic acid conjugates of naphthalene The Journal of Organic Chemistry. 58: 7548-7556. DOI: 10.1021/Jo00078A039 |
0.383 |
|
| 1993 |
Beebe X, Chiappari CL, Kurth MJ, Schore NE. An intramolecular 1,3-dipolar cycloaddition/electrophilic cyclization sequence to give cyclic ethers The Journal of Organic Chemistry. 58: 7320-7321. DOI: 10.1021/Jo00078A003 |
0.644 |
|
| 1993 |
McKew JC, Kurth MJ. Iterative enolate Claisen rearrangements: versatile route to optically pure 2,7-nonadiene-5-carboxylic acids The Journal of Organic Chemistry. 58: 4589-4595. DOI: 10.1021/Jo00069A019 |
0.31 |
|
| 1993 |
Duffy JL, Kurth JA, Kurth MJ. Erratum: Lithium, potassium, and sodium alkoxides: Donors in the Michael addition reaction of α-nitroolefins (Tetrahedron Letters, 1993, 34, 1259) Tetrahedron Letters. 34. DOI: 10.1016/S0040-4039(00)93365-3 |
0.305 |
|
| 1993 |
Borhan B, Nourooz-Zadeh J, Uematsu T, Hammock BD, Kurth MJ. Stereochemical aspects of cytosolic epoxide hydrolase hydration of methyl diepoxystearates Tetrahedron. 49: 2601-2612. DOI: 10.1016/S0040-4020(01)86339-0 |
0.643 |
|
| 1992 |
Nourooz-Zadeh J, Uematsu T, Borhan B, Kurth MJ, Hammock BD. Characterization of the cytosolic epoxide hydrolase-catalyzed hydration products from 9,10:12,13-diepoxy stearic esters. Archives of Biochemistry and Biophysics. 294: 675-85. PMID 1567223 DOI: 10.1016/0003-9861(92)90741-E |
0.626 |
|
| 1992 |
Kim HJ, Lee JH, Olmstead MM, Kurth MJ. A facile synthesis of furo[3,4-c]isoxazoles: precursors to 3,4-disubstituted isoxazoles The Journal of Organic Chemistry. 57: 6513-6519. DOI: 10.1021/Jo00050A027 |
0.397 |
|
| 1992 |
Moon HS, Schore NE, Kurth MJ. A polymer-supported chiral auxiliary applied to the iodolactonization reaction: preparation of .gamma.-butyrolactones The Journal of Organic Chemistry. 57: 6088-6089. DOI: 10.1021/Jo00049A003 |
0.6 |
|
| 1992 |
Beebe X, Schore NE, Kurth MJ. Polymer-supported synthesis of 2,5-disubstituted tetrahydrofurans Journal of the American Chemical Society. 114: 10061-10062. DOI: 10.1021/Ja00051A048 |
0.587 |
|
| 1992 |
Kurth M, Milco LA, Bryan Miller R. Trifunctional reagents for substrate-protein conjugation: application to pyrrolizidine alkaloid analogues. Tetrahedron. 48: 1407-1416. DOI: 10.1016/S0040-4020(01)92230-6 |
0.31 |
|
| 1991 |
Li QX, Zhao MS, Gee SJ, Kurth MJ, Seiber JN, Hammock BD. Development of enzyme-linked immunosorbent assays for 4-nitrophenol and substituted 4-nitrophenols Journal of Agricultural and Food Chemistry. 39: 1685-1692. DOI: 10.1021/Jf00009A028 |
0.384 |
|
| 1991 |
Tahir S, Olmstead MM, Kurth MJ. α-allylated chiral thioxanones: Diastereoselective preparation by an S-alkylation/[2,3]-sigmatropic rearrangement sequence. Tetrahedron Letters. 32: 335-338. DOI: 10.1016/S0040-4039(00)92621-2 |
0.325 |
|
| 1991 |
Rae Kim H, Jin Kim H, Duffy JL, Olmstead MM, Ruhlandt-Senge K, Kurth MJ. Double diastereoselectivity in the intramolecular nitrile oxide-olefin cycloaddition (INOC) reaction Tetrahedron Letters. 32: 4259-4262. DOI: 10.1016/S0040-4039(00)92143-9 |
0.357 |
|
| 1991 |
Reddy GN, Soares CJ, Kurth MJ, Segall HJ. Use of 2-dimethylaminopyridine in tritium and deuterium exchange reactions Journal of Labelled Compounds and Radiopharmaceuticals. 29: 1257-1260. DOI: 10.1002/Jlcr.2580291110 |
0.79 |
|
| 1990 |
Najdi S, Reichlin D, Kurth MJ. Enantioselective route to .gamma.-butyrolactones: chiral auxiliary mediated amide alkylation and iodolactonization The Journal of Organic Chemistry. 55: 6241-6244. DOI: 10.1021/Jo00313A005 |
0.322 |
|
| 1990 |
Kurth MJ, Tahir SH, Olmstead MM. A thioxanone-based chiral template: asymmetric induction in the [2,3]-sigmatropic rearrangement of sulfur ylides. Enantioselective preparation of C.beta.-chiral pent-4-enoic acids The Journal of Organic Chemistry. 55: 2286-2288. DOI: 10.1021/Jo00295A010 |
0.314 |
|
| 1990 |
Kurth MJ, Olmstead MM, Rodriguez MJ. Tandem 1,3-dipolar cycloaddition and electrophilic cyclization reactions: cyclic ether subunits of polyether antibiotics from unsaturated isoxazolines The Journal of Organic Chemistry. 55: 283-288. DOI: 10.1021/Jo00288A047 |
0.304 |
|
| 1990 |
Kurth MJ, Abreo MA. Vicinal epoxymesylates: substrates for iterative organocuprate Chemistry Tetrahedron. 46: 5085-5092. DOI: 10.1016/S0040-4020(01)87815-7 |
0.331 |
|
| 1989 |
Kurth MJ, Rodriguez MJ. A tandem 1,3-dipolar cycloaddition/electrophilic cyclization sequence: γ,δ-Unsaturated isoxazolines as precursors to ring-fused ethers Tetrahedron. 45: 6963-6968. DOI: 10.1016/S0040-4020(01)89162-6 |
0.347 |
|
| 1988 |
Kurth MJ, Green CB, Mount ME, Jackson DY. Polypeptide fluoroacetate derivatives. Synthesis and 19F n.m.r. International Journal of Peptide and Protein Research. 31: 388-95. PMID 3391744 DOI: 10.1111/J.1399-3011.1988.Tb00047.X |
0.303 |
|
| 1987 |
Kurth MJ, Soares CJ. Asymmetric aza-Claisen rearrangement: Synthesis of (+)-dihydropallescensin-2 [(+)-penlanpallescensin] Tetrahedron Letters. 28: 1031-1034. DOI: 10.1016/S0040-4039(00)95903-3 |
0.81 |
|
| 1985 |
Kurth MJ, O'Brien MJ. Desulfurization/.alpha.-alkylation of .beta.-keto sulfones The Journal of Organic Chemistry. 50: 3846-3848. DOI: 10.1021/Jo00220A033 |
0.355 |
|
| 1985 |
Kurth MJ, Brown EG, Hendra E, Hope H. Stereoselective synthesis of octahydro-3-oxospiro[benzofuran-2(3H),2'-[2H]pyran]systems The Journal of Organic Chemistry. 50: 1115-1117. DOI: 10.1021/Jo00207A039 |
0.308 |
|
| 1985 |
Kurth MJ, Decker OHW. Enantioselective preparation of 3-substituted 4-pentenoic acids via the Claisen rearrangement The Journal of Organic Chemistry. 50: 5769-5775. DOI: 10.1002/Chin.198629123 |
0.342 |
|
| 1985 |
Kurth MJ, O'Brien MJ, Hope H, Yanuck M. Intramolecular Diels-Alder reaction of 1-nitrodeca-1,6,8-trienes The Journal of Organic Chemistry. 50: 2626-2632. DOI: 10.1002/Chin.198602089 |
0.33 |
|
| 1985 |
KURTH MJ, YU C. ChemInform Abstract: ACYCLIC STEREOCONTROL THROUGH THE DIANIONIC CLAISEN REARRANGEMENT OF β-HYDROXY ESTERS: SYNTHESIS OF (.+-.)-BOTRYODIPLODIN Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198542364 |
0.312 |
|
| 1985 |
KURTH MJ, BROWN EG, HENDRA E, HOPE H. ChemInform Abstract: STEREOSELECTIVE SYNTHESIS OF OCTAHYDRO-3-OXOSPIRO(BENZOFURAN-2(3H),2′-(2H)PYRAN)SYSTEMS Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198535164 |
0.325 |
|
| 1984 |
Kurth MJ, Burns DH, O'Brien MJ. Ikarugamycin: total synthesis of the decahydro-as-indacene portion The Journal of Organic Chemistry. 49: 731-733. DOI: 10.1002/Chin.198428169 |
0.345 |
|
| 1983 |
Hoye T, Caruso A, Dellaria, Jr. J, Kurth M. Additions and Corrections - Two Syntheses of d,l-Aplysistatin Journal of the American Chemical Society. 105: 6531-6531. DOI: 10.1021/Ja00359A602 |
0.409 |
|
| 1983 |
Hoye TR, Kurth MJ. Preparation of d,l-megaphone intermediates Tetrahedron Letters. 24: 4769-4772. DOI: 10.1016/S0040-4039(00)94003-6 |
0.469 |
|
| 1983 |
Kurth MJ, Decker OH. Auxiliary-reagent mediated asymmetric induction in the aza-Claisen rearrangement Tetrahedron Letters. 24: 4535-4538. DOI: 10.1016/S0040-4039(00)85948-1 |
0.345 |
|
| 1983 |
HOYE TR, CARUSO AJ, DELLARIA JFJ, KURTH MJ. ChemInform Abstract: TWO SYNTHESES OF DL-APLYSISTATIN Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198309311 |
0.318 |
|
| 1982 |
Hoye TR, Caruso AJ, Dellaria JF, Kurth MJ. Two syntheses of dl-aplysistatin Journal of the American Chemical Society. 104: 6704-6709. DOI: 10.1021/Ja00388A038 |
0.323 |
|
| 1981 |
Hoye TR, Kurth MJ, Lo V. Triphenylcarbenium and tris(P-bromophenyl)ammoniumyl ion induced lactonizations of (ω-benzyloxy and ω-P-methoxybenzyloxy methyl esters Tetrahedron Letters. 22: 815-818. DOI: 10.1016/0040-4039(81)80004-4 |
0.459 |
|
| 1981 |
Hoye TR, Caruso AJ, Kurth MJ. Internal nucleophilic termination in mercuric ion initiated diene cyclizations Journal of Organic Chemistry. 46: 3550-3552. DOI: 10.1002/Chin.198202219 |
0.487 |
|
| 1979 |
Hoye TR, Kurth MJ. Total synthesis of dl-aplysistatin Journal of the American Chemical Society. 101: 5065-5067. DOI: 10.1021/Ja00511A047 |
0.489 |
|
| 1979 |
HOYE TR, KURTH MJ. ChemInform Abstract: TOTAL SYNTHESIS OF DL-APLYSISTATIN Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197948330 |
0.495 |
|
| Show low-probability matches. |
