Helen Horton - Publications

Affiliations: 
Global Health University of Washington, Seattle, Seattle, WA 
Area:
Immunology, Public Health

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 De Pooter D, Van Gulck E, Chen A, Evans CF, Neefs JM, Horton H, Boden D. A Therapeutic Hepatitis B Virus DNA Vaccine Induces Specific Immune Responses in Mice and Non-Human Primates. Vaccines. 9. PMID 34579206 DOI: 10.3390/vaccines9090969  0.344
2021 Kidzeru E, Gasper MA, Shao D, Edlefsen PT, Lejarcegui N, Havyarimana E, Urdahl K, Gantt S, Horton H, Jaspan H, Gervassi A. Myeloid-derived suppressor cells and their association with vaccine immunogenicity in South African infants. Journal of Leukocyte Biology. PMID 33477200 DOI: 10.1002/JLB.5A0420-281R  0.348
2020 Hollingshead N, Wu X, Kenerson H, Chen A, Strickland I, Horton H, Yeung R, Crispe IN. Functional responses of resident human T cells in intact liver tissue. Cellular Immunology. 360: 104275. PMID 33421676 DOI: 10.1016/j.cellimm.2020.104275  0.4
2017 Storey HL, Singa B, Naulikha J, Horton H, Richardson BA, John-Stewart G, Walson JL. Soil transmitted helminth infections are not associated with compromised antibody responses to previously administered measles and tetanus vaccines among HIV-1 infected, ART naïve Kenyan adults. Parasite Epidemiology and Control. 2: 13-20. PMID 28924616 DOI: 10.1016/J.Parepi.2016.12.003  0.503
2017 Dross S, Munson P, Gervassi A, Horton H, Fuller D. Myeloid-derived suppressor cells decrease T-cell responses to viral antigens and therapeutic conserved elements DNA vaccine and increase following analytic treatment interruption Journal of Virus Eradication. 3: 34. DOI: 10.1016/s2055-6640(20)30643-9  0.44
2016 Dross SE, Munson PV, Kim SE, Bratt DL, Tunggal HC, Gervassi AL, Fuller DH, Horton H. Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption. Journal of Immunology (Baltimore, Md. : 1950). PMID 27974456 DOI: 10.4049/Jimmunol.1600759  0.578
2014 Gervassi AL, Horton H. Is Infant Immunity Actively Suppressed or Immature? Virology : Research and Treatment. 2014: 1-9. PMID 25429207 DOI: 10.4137/VRT.S12248  0.458
2014 Gervassi A, Lejarcegui N, Dross S, Jacobson A, Itaya G, Kidzeru E, Gantt S, Jaspan H, Horton H. Myeloid derived suppressor cells are present at high frequency in neonates and suppress in vitro T cell responses. Plos One. 9: e107816. PMID 25248150 DOI: 10.1371/Journal.Pone.0107816  0.528
2014 Gantt S, Gervassi A, Jaspan H, Horton H. The role of myeloid-derived suppressor cells in immune ontogeny. Frontiers in Immunology. 5: 387. PMID 25165466 DOI: 10.3389/Fimmu.2014.00387  0.519
2014 Gasper MA, Kunwar P, Itaya G, Lejarcegui N, Bosire R, Maleche-Obimbo E, Wamalwa D, Slyker J, Overbaugh J, Horton H, Sodora DL, John-Stewart G, Lohman-Payne B. Natural killer cell and T-cell subset distributions and activation influence susceptibility to perinatal HIV-1 infection. Aids (London, England). 28: 1115-24. PMID 24752082 DOI: 10.1097/Qad.0000000000000263  0.648
2014 Gerns Storey HL, Richardson BA, Singa B, Naulikha J, Prindle VC, Diaz-Ochoa VE, Felgner PL, Camerini D, Horton H, John-Stewart G, Walson JL. Use of principal components analysis and protein microarray to explore the association of HIV-1-specific IgG responses with disease progression. Aids Research and Human Retroviruses. 30: 37-44. PMID 24134221 DOI: 10.1089/Aid.2013.0088  0.35
2013 Janes H, Friedrich DP, Krambrink A, Smith RJ, Kallas EG, Horton H, Casimiro DR, Carrington M, Geraghty DE, Gilbert PB, McElrath MJ, Frahm N. Vaccine-induced gag-specific T cells are associated with reduced viremia after HIV-1 infection. The Journal of Infectious Diseases. 208: 1231-9. PMID 23878319 DOI: 10.1093/Infdis/Jit322  0.685
2013 Hertz T, Ahmed H, Friedrich DP, Casimiro DR, Self SG, Corey L, McElrath MJ, Buchbinder S, Horton H, Frahm N, Robertson MN, Graham BS, Gilbert P. HIV-1 vaccine-induced T-cell responses cluster in epitope hotspots that differ from those induced in natural infection with HIV-1. Plos Pathogens. 9: e1003404. PMID 23818843 DOI: 10.1371/Journal.Ppat.1003404  0.553
2013 Jacobson A, Bell F, Lejarcegui N, Mitchell C, Frenkel L, Horton H. Healthy Neonates Possess a CD56-Negative NK Cell Population with Reduced Anti-Viral Activity. Plos One. 8: e67700. PMID 23805324 DOI: 10.1371/Journal.Pone.0067700  0.518
2013 Kunwar P, Hawkins N, Dinges WL, Liu Y, Gabriel EE, Swan DA, Stevens CE, Maenza J, Collier AC, Mullins JI, Hertz T, Yu X, Horton H. Superior control of HIV-1 replication by CD8+ T cells targeting conserved epitopes: implications for HIV vaccine design. Plos One. 8: e64405. PMID 23741326 DOI: 10.1371/Journal.Pone.0064405  0.67
2012 McClure J, Lovelace ES, Elahi S, Maurice NJ, Wagoner J, Dragavon J, Mittler JE, Kraft Z, Stamatatos L, Stamatatos L, Horton H, De Rosa SC, Coombs RW, Polyak SJ. Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation. Plos One. 7: e41832. PMID 22848626 DOI: 10.1371/Journal.Pone.0041832  0.618
2012 Elahi S, Horton H. Association of HLA-alleles with the immune regulation of chronic viral infections International Journal of Biochemistry and Cell Biology. 44: 1361-1365. PMID 22595281 DOI: 10.1016/J.Biocel.2012.05.003  0.543
2012 Elahi S, Niki T, Hirashima M, Horton H. Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection. Blood. 119: 4192-204. PMID 22438246 DOI: 10.1182/Blood-2011-11-389585  0.683
2012 McClure J, Lovelace ES, Elahi S, Maurice NJ, Wagoner J, Dragavon J, Mittler JE, Kraft Z, Stamatatos L, Horton H, Rosa SCD, Coombs RW, Polyak SJ. SIL inhibits stimulus-induced expansion of CD4+ T cells expressing the HIV co-receptors CXCR4 and CCR5 (panel A) but does not affect the relative frequency of CD4+ T cells expressing co-receptors (panel B). Plos One. DOI: 10.1371/Journal.Pone.0041832.G004  0.464
2012 McClure J, Lovelace ES, Elahi S, Maurice NJ, Wagoner J, Dragavon J, Mittler JE, Kraft Z, Stamatatos L, Horton H, De Rosa SC, Coombs RW, Polyak SJ. Correction: Silibinin Inhibits HIV-1 Infection by Reducing Cellular Activation and Proliferation Plos One. 7. DOI: 10.1371/Annotation/78Ba072A-6B7A-430A-8Fcd-Ef020E4Fc458  0.398
2012 Kunwar P, Hawkins N, Yu X, Liu Y, Collier A, Gabriel E, Hertz T, Horton H. Breadth or conservation score (CS): which is more important for HIV-1 T cell based vaccine immunogen design? Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P260  0.682
2011 Elahi S, Dinges WL, Lejarcegui N, Laing KJ, Collier AC, Koelle DM, McElrath MJ, Horton H. Protective HIV-specific CD8+ T cells evade Treg cell suppression. Nature Medicine. 17: 989-95. PMID 21765403 DOI: 10.1038/Nm.2422  0.608
2011 Friedrich D, Jalbert E, Dinges WL, Sidney J, Sette A, Huang Y, McElrath MJ, Horton H. Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target-specific regions of HIV-1. Journal of Acquired Immune Deficiency Syndromes (1999). 58: 248-52. PMID 21709567 DOI: 10.1097/QAI.0b013e318228f992  0.618
2011 He D, Kunwar P, Eskin E, Horton H, Gilbert P, Hertz T. Using HLA binding prediction algorithms for epitope mapping in HIV vaccine clinical trials 2011 Acm Conference On Bioinformatics, Computational Biology and Biomedicine, Bcb 2011. 594-601. DOI: 10.1145/2147805.2147907  0.544
2011 Elahi S, Dinges WL, Lejarcegui N, Laing KJ, Collier AC, Koelle DM, McElrath MJ, Horton H. Erratum: Corrigendum: Protective HIV-specific CD8+ T cells evade Treg cell suppression Nature Medicine. 17: 1153-1153. DOI: 10.1038/nm0911-1153a  0.624
2010 Dinges WL, Richardt J, Friedrich D, Jalbert E, Liu Y, Stevens CE, Maenza J, Collier AC, Geraghty DE, Smith J, Moodie Z, Mullins JI, McElrath MJ, Horton H. Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype. Journal of Virology. 84: 4461-8. PMID 20147397 DOI: 10.1128/Jvi.02438-09  0.599
2009 Malhotra U, Nolin J, Horton H, Li F, Corey L, Mullins JI, McElrath MJ. Functional properties and epitope characteristics of T-cells recognizing natural HIV-1 variants Vaccine. 27: 6678-6687. PMID 19747576 DOI: 10.1016/J.Vaccine.2009.08.093  0.646
2007 Horton H, Thomas EP, Stucky JA, Frank I, Moodie Z, Huang Y, Chiu YL, McElrath MJ, De Rosa SC. Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination Journal of Immunological Methods. 323: 39-54. PMID 17451739 DOI: 10.1016/j.jim.2007.03.002  0.472
2007 Fuller DH, Shipley T, Allen TM, Fuller JT, Wu MS, Horton H, Wilson N, Widera G, Watkins DI. Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques. Virology. 364: 245-55. PMID 17428516 DOI: 10.1016/J.Virol.2007.02.024  0.527
2007 Bull M, Lee D, Stucky J, Chiu YL, Rubin A, Horton H, McElrath MJ. Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials. Journal of Immunological Methods. 322: 57-69. PMID 17382342 DOI: 10.1016/J.Jim.2007.02.003  0.52
2007 Li F, Horton H, Gilbert PB, McElrath JM, Corey L, Self SG. HIV-1 CTL-based vaccine immunogen selection: antigen diversity and cellular response features. Current Hiv Research. 5: 97-107. PMID 17266561 DOI: 10.2174/157016207779316260  0.639
2007 Horton H, De Rosa SC. Does preserving memory correlate with surviving HIV? Trends in Microbiology. 15: 1-3. PMID 17112728 DOI: 10.1016/J.Tim.2006.11.001  0.62
2007 Russell ND, Graham BS, Keefer MC, McElrath MJ, Self SG, Weinhold KJ, Montefiori DC, Ferrari G, Horton H, Tomaras GD, Gurunathan S, Baglyos L, Frey SE, Mulligan MJ, Harro CD, et al. Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial. Journal of Acquired Immune Deficiency Syndromes (1999). 44: 203-12. PMID 17106277 DOI: 10.1097/01.Qai.0000248356.48501.Ff  0.544
2007 Goepfert PA, Tomaras GD, Horton H, Montefiori D, Ferrari G, Deers M, Voss G, Koutsoukos M, Pedneault L, Vandepapeliere P, McElrath MJ, Spearman P, Fuchs JD, Koblin BA, Blattner WA, et al. Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers. Vaccine. 25: 510-8. PMID 17049679 DOI: 10.1016/J.Vaccine.2006.07.050  0.589
2006 Horton H, Frank I, Baydo R, Jalbert E, Penn J, Wilson S, McNevin JP, McSweyn MD, Lee D, Huang Y, De Rosa SC, McElrath MJ. Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 7406-15. PMID 17082660  0.643
2006 Horton H, Havenar-Daughton C, Lee D, Moore E, Cao J, McNevin J, Andrus T, Zhu H, Rubin A, Zhu T, Celum C, McElrath MJ. Induction of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses in HIV vaccine trial participants who subsequently acquire HIV-1 infection Journal of Virology. 80: 9779-9788. PMID 16973582 DOI: 10.1128/JVI.00794-06  0.729
2006 Yu J, Chen H, Horton H, Bansal A, McElrath JM, Reichman R, Goepfert P, Jin X. Interleukin-2 reconstitutes defective human immunodeficiency virus (HIV), and cytomegalovirus (CMV) specific CD8+ T cell proliferation in HIV infection. Journal of Medical Virology. 78: 1147-57. PMID 16847956 DOI: 10.1002/Jmv.20675  0.663
2005 Goepfert PA, Horton H, McElrath MJ, Gurunathan S, Ferrari G, Tomaras GD, Montefiori DC, Allen M, Chiu YL, Spearman P, Fuchs JD, Koblin BA, Blattner WA, Frey S, Keefer MC, et al. High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects. The Journal of Infectious Diseases. 192: 1249-59. PMID 16136469 DOI: 10.1086/432915  0.532
2005 Maecker HT, Rinfret A, D'Souza P, Darden J, Roig E, Landry C, Hayes P, Birungi J, Anzala O, Garcia M, Harari A, Frank I, Baydo R, Baker M, Holbrook J, ... ... Horton H, et al. Standardization of cytokine flow cytometry assays Bmc Immunology. 6. PMID 15978127 DOI: 10.1186/1471-2172-6-13  0.33
2004 Horton H, Russell N, Moore E, Frank I, Baydo R, Havenar-Daughton C, Lee D, Deers M, Hudgens M, Weinhold K, McElrath MJ. Correlation between interferon-γ secretion and cytotoxicity, in virus-specific memory T cells Journal of Infectious Diseases. 190: 1692-1696. PMID 15478077 DOI: 10.1086/424490  0.534
2004 Hudgens MG, Self SG, Chiu YL, Russell ND, Horton H, McElrath MJ. Statistical considerations for the design and analysis of the ELISpot assay in HIV-1 vaccine trials. Journal of Immunological Methods. 288: 19-34. PMID 15183082 DOI: 10.1016/J.Jim.2004.01.018  0.645
2002 Vogel TU, Friedrich TC, O'Connor DH, Rehrauer W, Dodds EJ, Hickman H, Hildebrand W, Sidney J, Sette A, Hughes A, Horton H, Vielhuber K, Rudersdorf R, De Souza IP, Reynolds MR, et al. Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence? Journal of Virology. 76: 11623-36. PMID 12388723 DOI: 10.1128/Jvi.76.22.11623-11636.2002  0.385
2002 Vogel TU, Horton H, Fuller DH, Carter DK, Vielhuber K, O'Connor DH, Shipley T, Fuller J, Sutter G, Erfle V, Wilson N, Picker LJ, Watkins DI. Differences between T cell epitopes recognized after immunization and after infection. Journal of Immunology (Baltimore, Md. : 1950). 169: 4511-21. PMID 12370388 DOI: 10.4049/Jimmunol.169.8.4511  0.503
2002 Allen TM, Jing P, Calore B, Horton H, O'Connor DH, Hanke T, Piekarczyk M, Ruddersdorf R, Mothé BR, Emerson C, Wilson N, Lifson JD, Belyakov IM, Berzofsky JA, Wang C, et al. Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. Journal of Virology. 76: 10507-11. PMID 12239328 DOI: 10.1128/Jvi.76.20.10507-10511.2002  0.532
2002 Horton H, Vogel TU, Carter DK, Vielhuber K, Fuller DH, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Montefiori DC, Erfle V, Desrosiers RC, Wilson N, Picker LJ, Wolinsky SM, et al. Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. Journal of Virology. 76: 7187-202. PMID 12072518 DOI: 10.1128/Jvi.76.14.7187-7202.2002  0.431
2002 O'Connor DH, Allen TM, Vogel TU, Jing P, DeSouza IP, Dodds E, Dunphy EJ, Melsaether C, Mothé B, Yamamoto H, Horton H, Wilson N, Hughes AL, Watkins DI. Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection. Nature Medicine. 8: 493-9. PMID 11984594 DOI: 10.1038/Nm0502-493  0.473
2002 Horton H, Vogel T, O'Connor D, Picker L, Watkins DI. Analysis of the immune response and viral evolution during the acute phase of SIV infection. Vaccine. 20: 1927-32. PMID 11983247 DOI: 10.1016/S0264-410X(02)00069-5  0.494
2002 Mothé BR, Horton H, Carter DK, Allen TM, Liebl ME, Skinner P, Vogel TU, Fuenger S, Vielhuber K, Rehrauer W, Wilson N, Franchini G, Altman JD, Haase A, Picker LJ, et al. Dominance of CD8 responses specific for epitopes bound by a single major histocompatibility complex class I molecule during the acute phase of viral infection. Journal of Virology. 76: 875-84. PMID 11752176 DOI: 10.1128/Jvi.76.2.875-884.2002  0.398
1999 Evans DT, O'Connor DH, Jing P, Dzuris JL, Sidney J, da Silva J, Allen TM, Horton H, Venham JE, Rudersdorf RA, Vogel T, Pauza CD, Bontrop RE, DeMars R, Sette A, et al. Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef. Nature Medicine. 5: 1270-6. PMID 10545993 DOI: 10.1038/15224  0.325
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