| Year |
Citation |
Score |
| 2020 |
Anilkumar U, Khacho M, Cuillerier A, Harris R, Patten DA, Bilen M, Iqbal MA, Guo DY, Trudeau LE, Park DS, Harper ME, Burelle Y, Slack RS. MCL-1 maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions. Cell Death & Disease. 11: 321. PMID 32371858 DOI: 10.1038/S41419-020-2498-9 |
0.477 |
|
| 2019 |
Farzam A, Chohan K, Strmiskova M, Hewitt SJ, Park DS, Pezacki JP, Özcelik D. A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death. Redox Biology. 28: 101377. PMID 31760358 DOI: 10.1016/J.Redox.2019.101377 |
0.46 |
|
| 2019 |
Shutinoski B, Hakimi M, Harmsen IE, Lunn M, Rocha J, Lengacher N, Zhou YY, Khan J, Nguyen A, Hake-Volling Q, El-Kodsi D, Li J, Alikashani A, Beauchamp C, Majithia J, ... ... Park DS, et al. alleles modulate inflammation during microbial infection of mice in a sex-dependent manner. Science Translational Medicine. 11. PMID 31554740 DOI: 10.1126/Scitranslmed.Aas9292 |
0.72 |
|
| 2019 |
Huang T, González YR, Qu D, Huang E, Safarpour F, Wang E, Joselin A, Im DS, Callaghan SM, Boonying W, Julian L, Dunwoodie SL, Slack RS, Park DS. The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors. The Journal of Biological Chemistry. PMID 30967472 DOI: 10.1074/Jbc.Ra119.007941 |
0.446 |
|
| 2019 |
Theurey P, Connolly NMC, Fortunati I, Basso E, Lauwen S, Ferrante C, Moreira Pinho C, Joselin A, Gioran A, Bano D, Park DS, Ankarcrona M, Pizzo P, Prehn JHM. Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons. Aging Cell. e12924. PMID 30793475 DOI: 10.1111/Acel.12924 |
0.381 |
|
| 2019 |
Yang J, Kim KS, Iyirhiaro GO, Marcogliese PC, Callaghan SM, Qu D, Kim WJ, Slack RS, Park DS. DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress. Cell Death & Disease. 10: 135. PMID 30755590 DOI: 10.1038/S41419-019-1354-2 |
0.776 |
|
| 2019 |
Boonying W, Joselin A, Huang E, Qu D, Safarpour F, Iyirhiaro GO, Rodriguez Gonzalez Y, Callaghan SM, Slack RS, Figeys D, Chung YH, Park DS. Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP. Journal of Neurochemistry. PMID 30734931 DOI: 10.1111/Jnc.14683 |
0.573 |
|
| 2018 |
Kim KS, Marcogliese PC, Yang J, Callaghan SM, Resende V, Abdel-Messih E, Marras C, Visanji NP, Huang J, Schlossmacher MG, Trinkle-Mulcahy L, Slack RS, Lang AE, Park DS. Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29760073 DOI: 10.1073/Pnas.1718946115 |
0.746 |
|
| 2018 |
Giguere N, Pacelli C, Saumure C, Bourque MJ, Matheoud D, Levesque D, Slack RS, Park DS, Trudeau LE. Comparative analysis of Parkinson's disease-associated genes reveals altered survival and bioenergetics of parkin-deficient dopamine neurons in mice. The Journal of Biological Chemistry. PMID 29700116 DOI: 10.1074/Jbc.Ra117.000499 |
0.531 |
|
| 2017 |
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, ... ... Park DS, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4 |
0.309 |
|
| 2017 |
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, ... ... Park DS, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4 |
0.309 |
|
| 2017 |
Huang E, Qu D, Huang T, Rizzi N, Boonying W, Krolak D, Ciana P, Woulfe J, Klein C, Slack RS, Figeys D, Park DS. PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress. Nature Communications. 8: 1399. PMID 29123128 DOI: 10.1038/S41467-017-01435-1 |
0.505 |
|
| 2017 |
Mittal S, Bjørnevik K, Im DS, Flierl A, Dong X, Locascio JJ, Abo KM, Long E, Jin M, Xu B, Xiang YK, Rochet JC, Engeland A, Rizzu P, Heutink P, ... ... Park DS, et al. β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease. Science (New York, N.Y.). 357: 891-898. PMID 28860381 DOI: 10.1126/Science.Aaf3934 |
0.356 |
|
| 2017 |
Iyirhiaro GO, Soon Im D, Boonying W, Callaghan SM, During MJ, Slack RS, Park DS. Cdc25A is a critical mediator of ischemic neuronal death in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28607169 DOI: 10.1523/Jneurosci.3017-16.2017 |
0.576 |
|
| 2017 |
Khacho M, Clark A, Svoboda DS, MacLaurin JG, Lagace DC, Park DS, Slack RS. Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis. Human Molecular Genetics. PMID 28595361 DOI: 10.1093/Hmg/Ddx217 |
0.327 |
|
| 2017 |
Marcogliese PC, Abuaish S, Kabbach G, Abdel-Messih E, Seang S, Li G, Slack RS, Emdadul Haque M, Venderova K, Park DS. LRRK2(I2020T) Functional Genetic Interactors that Modify Eye Degeneration and Dopaminergic Cell Loss in Drosophila. Human Molecular Genetics. PMID 28158614 DOI: 10.1093/Hmg/Ddx030 |
0.771 |
|
| 2016 |
Vandenbosch R, Clark A, Fong BC, Omais S, Jaafar C, Dugal-Tessier D, Dhaliwal J, Lagace DC, Park DS, Ghanem N, Slack RS. RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus. Hippocampus. PMID 27325572 DOI: 10.1002/Hipo.22613 |
0.314 |
|
| 2016 |
Khacho M, Clark A, Svoboda DS, Azzi J, MacLaurin JG, Meghaizel C, Sesaki H, Lagace DC, Germain M, Harper ME, Park DS, Slack RS. Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program. Cell Stem Cell. PMID 27237737 DOI: 10.1016/J.Stem.2016.04.015 |
0.303 |
|
| 2015 |
Qu D, Hage A, Don-Carolis K, Huang E, Joselin A, Safarpour F, Marcogliese PC, Rousseaux MW, Hewitt SJ, Huang T, Im DS, Callaghan S, Dewar-Darch D, Figeys D, Slack RS, ... Park DS, et al. Bag2 Mediated Regulation of Pink1 is Critical for Mitochondrial Translocation of Parkin and Neuronal Survival. The Journal of Biological Chemistry. PMID 26538564 DOI: 10.1074/Jbc.M115.677815 |
0.829 |
|
| 2015 |
Jahani-Asl A, Huang E, Irrcher I, Rashidian J, Ishihara N, Lagace DC, Slack RS, Park DS. CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death. Human Molecular Genetics. 24: 4573-83. PMID 26002103 DOI: 10.1093/Hmg/Ddv188 |
0.498 |
|
| 2015 |
Svoboda DS, Clark A, Park DS, Slack RS. Induction of protein deletion through in utero electroporation to define deficits in neuronal migration in transgenic models. Journal of Visualized Experiments : Jove. 51983. PMID 25650557 DOI: 10.3791/51983 |
0.344 |
|
| 2015 |
Yang J, Wu Z, Renier N, Simon DJ, Uryu K, Park DS, Greer PA, Tournier C, Davis RJ, Tessier-Lavigne M. Pathological axonal death through a MAPK cascade that triggers a local energy deficit. Cell. 160: 161-76. PMID 25594179 DOI: 10.1016/J.Cell.2014.11.053 |
0.323 |
|
| 2014 |
Jeong YM, Jin TE, Choi JH, Lee MS, Kim HT, Hwang KS, Park DS, Oh HW, Choi JK, Korzh V, Schachner M, You KH, Kim CH. Induction of clusterin expression by neuronal cell death in Zebrafish. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 41: 583-9. PMID 25434681 DOI: 10.1016/J.Jgg.2014.08.007 |
0.449 |
|
| 2014 |
Patten DA, Wong J, Khacho M, Soubannier V, Mailloux RJ, Pilon-Larose K, MacLaurin JG, Park DS, McBride HM, Trinkle-Mulcahy L, Harper ME, Germain M, Slack RS. OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand. The Embo Journal. 33: 2676-91. PMID 25298396 DOI: 10.15252/Embj.201488349 |
0.322 |
|
| 2014 |
Parsanejad M, Bourquard N, Qu D, Zhang Y, Huang E, Rousseaux MW, Aleyasin H, Irrcher I, Callaghan S, Vaillant DC, Kim RH, Slack RS, Mak TW, Reddy ST, Figeys D, ... Park DS, et al. DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. Plos One. 9: e106601. PMID 25210784 DOI: 10.1371/Journal.Pone.0106601 |
0.814 |
|
| 2014 |
Parsanejad M, Zhang Y, Qu D, Irrcher I, Rousseaux MW, Aleyasin H, Kamkar F, Callaghan S, Slack RS, Mak TW, Lee S, Figeys D, Park DS. Regulation of the VHL/HIF-1 pathway by DJ-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8043-50. PMID 24899725 DOI: 10.1523/Jneurosci.1244-13.2014 |
0.821 |
|
| 2014 |
Iyirhiaro GO, Zhang Y, Estey C, O'Hare MJ, Safarpour F, Parsanejad M, Wang S, Abdel-Messih E, Callaghan SM, During MJ, Slack RS, Park DS. Regulation of ischemic neuronal death by E2F4-p130 protein complexes. The Journal of Biological Chemistry. 289: 18202-13. PMID 24828495 DOI: 10.1074/Jbc.M114.574145 |
0.841 |
|
| 2014 |
Sanchez G, Varaschin RK, Büeler H, Marcogliese PC, Park DS, Trudeau LE. Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice. Plos One. 9: e94826. PMID 24733019 DOI: 10.1371/Journal.Pone.0094826 |
0.766 |
|
| 2014 |
Khacho M, Tarabay M, Patten D, Khacho P, MacLaurin JG, Guadagno J, Bergeron R, Cregan SP, Harper ME, Park DS, Slack RS. Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival. Nature Communications. 5: 3550. PMID 24686499 DOI: 10.1038/Ncomms4550 |
0.312 |
|
| 2013 |
Svoboda DS, Paquin A, Park DS, Slack RS. Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis. Developmental Biology. 384: 101-13. PMID 24056077 DOI: 10.1016/J.Ydbio.2013.09.015 |
0.454 |
|
| 2013 |
Andrusiak MG, Vandenbosch R, Dick FA, Park DS, Slack RS. LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence. Cell Cycle (Georgetown, Tex.). 12: 1416-23. PMID 23574720 DOI: 10.4161/Cc.24527 |
0.462 |
|
| 2013 |
Mount MP, Zhang Y, Amini M, Callaghan S, Kulczycki J, Mao Z, Slack RS, Anisman H, Park DS. Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The Journal of Biological Chemistry. 288: 14362-71. PMID 23536182 DOI: 10.1074/Jbc.M112.439216 |
0.51 |
|
| 2013 |
Amini M, Ma CL, Farazifard R, Zhu G, Zhang Y, Vanderluit J, Zoltewicz JS, Hage F, Savitt JM, Lagace DC, Slack RS, Beique JC, Baudry M, Greer PA, Bergeron R, ... Park DS, et al. Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5773-84. PMID 23536090 DOI: 10.1523/Jneurosci.4247-12.2013 |
0.5 |
|
| 2013 |
Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS. Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 12: 440-52. PMID 23499385 DOI: 10.1016/J.Stem.2013.02.001 |
0.314 |
|
| 2013 |
Germain M, Nguyen AP, Khacho M, Patten DA, Screaton RA, Park DS, Slack RS. LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction. Human Molecular Genetics. 22: 952-62. PMID 23187960 DOI: 10.1093/hmg/dds500 |
0.411 |
|
| 2013 |
Rousseaux MWC, Marcogliese PC, Qu D, Hewitt SJ, Seang S, Kim RH, Slack RS, Schlossmacher MG, Lagace DC, Mak TW, Park DS. Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 39 (15918-15923)) Proceedings of the National Academy of Sciences of the United States of America. 110: 11212. DOI: 10.1073/pnas.1310560110 |
0.693 |
|
| 2012 |
Andrusiak MG, Vandenbosch R, Park DS, Slack RS. The retinoblastoma protein is essential for survival of postmitotic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14809-14. PMID 23077065 DOI: 10.1523/Jneurosci.1912-12.2012 |
0.546 |
|
| 2012 |
Rousseaux MW, Marcogliese PC, Qu D, Hewitt SJ, Seang S, Kim RH, Slack RS, Schlossmacher MG, Lagace DC, Mak TW, Park DS. Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 15918-23. PMID 23019375 DOI: 10.1073/Pnas.1205102109 |
0.799 |
|
| 2012 |
Venderova K, Park DS. Programmed cell death in Parkinson's disease. Cold Spring Harbor Perspectives in Medicine. 2. PMID 22908196 DOI: 10.1101/cshperspect.a009365 |
0.339 |
|
| 2012 |
Joselin AP, Hewitt SJ, Callaghan SM, Kim RH, Chung YH, Mak TW, Shen J, Slack RS, Park DS. ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. Human Molecular Genetics. 21: 4888-903. PMID 22872702 DOI: 10.1093/Hmg/Dds325 |
0.581 |
|
| 2012 |
Haque ME, Mount MP, Safarpour F, Abdel-Messih E, Callaghan S, Mazerolle C, Kitada T, Slack RS, Wallace V, Shen J, Anisman H, Park DS. Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1. The Journal of Biological Chemistry. 287: 23162-70. PMID 22511790 DOI: 10.1074/Jbc.M112.346437 |
0.484 |
|
| 2012 |
Greene AW, Grenier K, Aguileta MA, Muise S, Farazifard R, Haque ME, McBride HM, Park DS, Fon EA. Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. Embo Reports. 13: 378-85. PMID 22354088 DOI: 10.1038/Embor.2012.14 |
0.365 |
|
| 2012 |
Xilouri M, Kyratzi E, Pitychoutis PM, Papadopoulou-Daifoti Z, Perier C, Vila M, Maniati M, Ulusoy A, Kirik D, Park DS, Wada K, Stefanis L. Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system. Human Molecular Genetics. 21: 874-89. PMID 22076440 DOI: 10.1093/Hmg/Ddr521 |
0.413 |
|
| 2011 |
Imai Y, Venderova K, Park DS, Cai H, Schmidt E. Animal models of Parkinson's disease. Parkinson's Disease. 2011: 364328. PMID 22220287 DOI: 10.4061/2011/364328 |
0.474 |
|
| 2011 |
Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, et al. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 795-808. PMID 21552986 DOI: 10.1007/S00702-011-0653-2 |
0.344 |
|
| 2011 |
Germain M, Nguyen AP, Le Grand JN, Arbour N, Vanderluit JL, Park DS, Opferman JT, Slack RS. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. The Embo Journal. 30: 395-407. PMID 21139567 DOI: 10.1038/Emboj.2010.327 |
0.454 |
|
| 2011 |
Bouman L, Schlierf A, Lutz AK, Shan J, Deinlein A, Kast J, Galehdar Z, Palmisano V, Patenge N, Berg D, Gasser T, Augustin R, Trümbach D, Irrcher I, Park DS, et al. Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress. Cell Death and Differentiation. 18: 769-82. PMID 21113145 DOI: 10.1038/Cdd.2010.142 |
0.405 |
|
| 2011 |
Andrusiak MG, McClellan KA, Dugal-Tessier D, Julian LM, Rodrigues SP, Park DS, Kennedy TE, Slack RS. Rb/E2F regulates expression of neogenin during neuronal migration. Molecular and Cellular Biology. 31: 238-47. PMID 21059867 DOI: 10.1128/Mcb.00378-10 |
0.454 |
|
| 2011 |
Jahani-Asl A, Pilon-Larose K, Xu W, MacLaurin JG, Park DS, McBride HM, Slack RS. The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity. The Journal of Biological Chemistry. 286: 4772-82. PMID 21041314 DOI: 10.1074/jbc.M110.167155 |
0.389 |
|
| 2010 |
Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP. Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16938-48. PMID 21159964 DOI: 10.1523/Jneurosci.1598-10.2010 |
0.428 |
|
| 2010 |
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, ... ... Park DS, et al. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Human Molecular Genetics. 19: 3734-46. PMID 20639397 DOI: 10.1093/Hmg/Ddq288 |
0.826 |
|
| 2010 |
Kanao T, Venderova K, Park DS, Unterman T, Lu B, Imai Y. Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila. Human Molecular Genetics. 19: 3747-58. PMID 20624856 DOI: 10.1093/Hmg/Ddq289 |
0.553 |
|
| 2010 |
Huang E, Qu D, Zhang Y, Venderova K, Haque ME, Rousseaux MW, Slack RS, Woulfe JM, Park DS. The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nature Cell Biology. 12: 563-71. PMID 20473298 DOI: 10.1038/Ncb2058 |
0.816 |
|
| 2010 |
Biswas SC, Zhang Y, Iyirhiaro G, Willett RT, Rodriguez Gonzalez Y, Cregan SP, Slack RS, Park DS, Greene LA. Sertad1 plays an essential role in developmental and pathological neuron death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3973-82. PMID 20237268 DOI: 10.1523/Jneurosci.6421-09.2010 |
0.84 |
|
| 2010 |
Aleyasin H, Rousseaux MW, Marcogliese PC, Hewitt SJ, Irrcher I, Joselin AP, Parsanejad M, Kim RH, Rizzu P, Callaghan SM, Slack RS, Mak TW, Park DS. DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3186-91. PMID 20133695 DOI: 10.1073/Pnas.0914876107 |
0.815 |
|
| 2010 |
Zhang Y, Parsanejad M, Huang E, Qu D, Aleyasin H, Rousseaux MW, Gonzalez YR, Cregan SP, Slack RS, Park DS. Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage. Journal of Neurochemistry. 112: 497-510. PMID 19895669 DOI: 10.1111/J.1471-4159.2009.06476.X |
0.82 |
|
| 2010 |
Andrusiak M, McClellan K, Dugal‐Tessier D, Park D, Kennedy T, Slack R. [P1.51]: Rb/E2F regulation of neogenin modulates netrin‐1 induced neuronal migration International Journal of Developmental Neuroscience. 28: 672-672. DOI: 10.1016/J.Ijdevneu.2010.07.091 |
0.486 |
|
| 2009 |
Ryan SD, Whitehead SN, Swayne LA, Moffat TC, Hou W, Ethier M, Bourgeois AJ, Rashidian J, Blanchard AP, Fraser PE, Park DS, Figeys D, Bennett SA. Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism. Proceedings of the National Academy of Sciences of the United States of America. 106: 20936-41. PMID 19926863 DOI: 10.1073/Pnas.0905654106 |
0.314 |
|
| 2009 |
Rashidian J, Rousseaux MW, Venderova K, Qu D, Callaghan SM, Phillips M, Bland RJ, During MJ, Mao Z, Slack RS, Park DS. Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12497-505. PMID 19812325 DOI: 10.1523/Jneurosci.3892-09.2009 |
0.775 |
|
| 2009 |
Venderova K, Kabbach G, Abdel-Messih E, Zhang Y, Parks RJ, Imai Y, Gehrke S, Ngsee J, Lavoie MJ, Slack RS, Rao Y, Zhang Z, Lu B, Haque ME, Park DS. Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. Human Molecular Genetics. 18: 4390-404. PMID 19692353 DOI: 10.1093/Hmg/Ddp394 |
0.447 |
|
| 2009 |
Xilouri M, Vogiatzi T, Vekrellis K, Park D, Stefanis L. Abberant α-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy Plos One. 4. PMID 19436756 DOI: 10.1371/Journal.Pone.0005515 |
0.551 |
|
| 2009 |
Irrcher I, Park DS. Parkinson's disease: to live or die by autophagy. Science Signaling. 2: pe21. PMID 19351953 DOI: 10.1126/Scisignal.265Pe21 |
0.502 |
|
| 2009 |
Dagda RK, Cherra SJ, Kulich SM, Tandon A, Park D, Chu CT. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. The Journal of Biological Chemistry. 284: 13843-55. PMID 19279012 DOI: 10.1074/Jbc.M808515200 |
0.32 |
|
| 2009 |
Grant RJ, Sellings LH, Crocker SJ, Melloni E, Park DS, Clarke PB. Effects of calpain inhibition on dopaminergic markers and motor function following intrastriatal 6-hydroxydopamine administration in rats. Neuroscience. 158: 558-69. PMID 19007862 DOI: 10.1016/J.Neuroscience.2008.10.023 |
0.699 |
|
| 2009 |
Imai Y, Kanao T, Venderova K, Park D, Lu B. Phosphorylation of FoxO by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.208 |
0.518 |
|
| 2008 |
Arbour N, Vanderluit JL, Le Grand JN, Jahani-Asl A, Ruzhynsky VA, Cheung EC, Kelly MA, MacKenzie AE, Park DS, Opferman JT, Slack RS. Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6068-78. PMID 18550749 DOI: 10.1523/Jneurosci.4940-07.2008 |
0.462 |
|
| 2008 |
Gonzalez YR, Zhang Y, Behzadpoor D, Cregan S, Bamforth S, Slack RS, Park DS. CITED2 signals through peroxisome proliferator-activated receptor-gamma to regulate death of cortical neurons after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5559-69. PMID 18495890 DOI: 10.1523/Jneurosci.1014-08.2008 |
0.438 |
|
| 2008 |
Haque ME, Thomas KJ, D'Souza C, Callaghan S, Kitada T, Slack RS, Fraser P, Cookson MR, Tandon A, Park DS. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America. 105: 1716-21. PMID 18218782 DOI: 10.1073/Pnas.0705363105 |
0.491 |
|
| 2008 |
Iyirhiaro GO, Brust TB, Rashidian J, Galehdar Z, Osman A, Phillips M, Slack RS, Macvicar BA, Park DS. Delayed combinatorial treatment with flavopiridol and minocycline provides longer term protection for neuronal soma but not dendrites following global ischemia. Journal of Neurochemistry. 105: 703-13. PMID 18205749 DOI: 10.1111/J.1471-4159.2007.05166.X |
0.434 |
|
| 2008 |
Keramaris E, Ruzhynsky VA, Callaghan SM, Wong E, Davis RJ, Flavell R, Slack RS, Park DS. Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice. The Journal of Biological Chemistry. 283: 405-15. PMID 17984095 DOI: 10.1074/Jbc.M701552200 |
0.347 |
|
| 2007 |
Aleyasin H, Rousseaux MW, Phillips M, Kim RH, Bland RJ, Callaghan S, Slack RS, During MJ, Mak TW, Park DS. The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proceedings of the National Academy of Sciences of the United States of America. 104: 18748-53. PMID 18003894 DOI: 10.1073/Pnas.0709379104 |
0.805 |
|
| 2007 |
Qu D, Rashidian J, Mount MP, Aleyasin H, Parsanejad M, Lira A, Haque E, Zhang Y, Callaghan S, Daigle M, Rousseaux MW, Slack RS, Albert PR, Vincent I, Woulfe JM, ... Park DS, et al. Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron. 55: 37-52. PMID 17610816 DOI: 10.1016/J.Neuron.2007.05.033 |
0.826 |
|
| 2007 |
Qu D, Zhang Y, Ma J, Guo K, Li R, Yin Y, Cao X, Park DS. The nuclear localization of SET mediated by impalpha3/impbeta attenuates its cytosolic toxicity in neurons. Journal of Neurochemistry. 103: 408-22. PMID 17608644 DOI: 10.1111/J.1471-4159.2007.04747.X |
0.437 |
|
| 2007 |
Vanderluit JL, Wylie CA, McClellan KA, Ghanem N, Fortin A, Callaghan S, MacLaurin JG, Park DS, Slack RS. The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate. The Journal of Cell Biology. 178: 129-39. PMID 17591923 DOI: 10.1083/Jcb.200703176 |
0.443 |
|
| 2007 |
Jahani-Asl A, Cheung EC, Neuspiel M, MacLaurin JG, Fortin A, Park DS, McBride HM, Slack RS. Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death. The Journal of Biological Chemistry. 282: 23788-98. PMID 17537722 DOI: 10.1074/jbc.M703812200 |
0.47 |
|
| 2007 |
McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS. Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Molecular and Cellular Biology. 27: 4825-43. PMID 17452454 DOI: 10.1128/Mcb.02100-06 |
0.461 |
|
| 2007 |
Mount MP, Lira A, Grimes D, Smith PD, Faucher S, Slack R, Anisman H, Hayley S, Park DS. Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3328-37. PMID 17376993 DOI: 10.1523/Jneurosci.5321-06.2007 |
0.4 |
|
| 2007 |
Rashidian J, Iyirhiaro GO, Park DS. Cell cycle machinery and stroke Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1772: 484-493. PMID 17241774 DOI: 10.1016/J.Bbadis.2006.11.009 |
0.534 |
|
| 2006 |
Lee J, Kosaras B, Aleyasin H, Han JA, Park DS, Ratan RR, Kowall NW, Ferrante RJ, Lee SW, Ryu H. Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2375-7. PMID 17012241 DOI: 10.1096/Fj.06-5957Fje |
0.798 |
|
| 2006 |
Zhang Y, Qu D, Morris EJ, O'Hare MJ, Callaghan SM, Slack RS, Geller HM, Park DS. The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8819-28. PMID 16928871 DOI: 10.1523/JNEUROSCI.2593-06.2006 |
0.464 |
|
| 2006 |
Cheung EC, Joza N, Steenaart NA, McClellan KA, Neuspiel M, McNamara S, MacLaurin JG, Rippstein P, Park DS, Shore GC, McBride HM, Penninger JM, Slack RS. Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis. The Embo Journal. 25: 4061-73. PMID 16917506 DOI: 10.1038/Sj.Emboj.7601276 |
0.468 |
|
| 2006 |
Massa PT, Aleyasin H, Park DS, Mao X, Barger SW. NFkappaB in neurons? The uncertainty principle in neurobiology. Journal of Neurochemistry. 97: 607-18. PMID 16573643 DOI: 10.1111/J.1471-4159.2006.03810.X |
0.736 |
|
| 2006 |
Smith PD, Mount MP, Shree R, Callaghan S, Slack RS, Anisman H, Vincent I, Wang X, Mao Z, Park DS. Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 440-7. PMID 16407541 DOI: 10.1523/Jneurosci.2875-05.2006 |
0.54 |
|
| 2006 |
Crocker SJ, Hayley SP, Smith PD, Mount MP, Lamba WR, Callaghan SM, Slack RS, Park DS. Regulation of axotomy-induced dopaminergic neuron death and c-Jun phosphorylation by targeted inhibition of cdc42 or mixed lineage kinase. Journal of Neurochemistry. 96: 489-99. PMID 16336220 DOI: 10.1111/J.1471-4159.2005.03568.X |
0.756 |
|
| 2005 |
Lamba W, Prichett W, Munoz D, Park DS, Woulfe JM. MPTP induces intranuclear rodlet formation in midbrain dopaminergic neurons. Brain Research. 1066: 86-91. PMID 16325158 DOI: 10.1016/J.Brainres.2005.10.058 |
0.488 |
|
| 2005 |
O'Hare MJ, Kushwaha N, Zhang Y, Aleyasin H, Callaghan SM, Slack RS, Albert PR, Vincent I, Park DS. Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8954-66. PMID 16192386 DOI: 10.1523/Jneurosci.2899-05.2005 |
0.77 |
|
| 2005 |
Rashidian J, Iyirhiaro G, Aleyasin H, Rios M, Vincent I, Callaghan S, Bland RJ, Slack RS, During MJ, Park DS. Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 14080-5. PMID 16166266 DOI: 10.1073/Pnas.0500099102 |
0.773 |
|
| 2005 |
Tang X, Wang X, Gong X, Tong M, Park D, Xia Z, Mao Z. Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4823-34. PMID 15888658 DOI: 10.1523/Jneurosci.1331-05.2005 |
0.521 |
|
| 2005 |
Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, Pownall S, Wakeham A, You-Ten AJ, Kalia SK, Horne P, Westaway D, Lozano AM, Anisman H, Park DS, Mak TW. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 102: 5215-20. PMID 15784737 DOI: 10.1073/Pnas.0501282102 |
0.783 |
|
| 2005 |
Cheung EC, Melanson-Drapeau L, Cregan SP, Vanderluit JL, Ferguson KL, McIntosh WC, Park DS, Bennett SA, Slack RS. Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1324-34. PMID 15703386 DOI: 10.1523/Jneurosci.4261-04.2005 |
0.452 |
|
| 2005 |
Keramaris E, Vanderluit JL, Bahadori M, Mousavi K, Davis RJ, Flavell R, Slack RS, Park DS. c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation. The Journal of Biological Chemistry. 280: 1132-41. PMID 15528206 DOI: 10.1074/Jbc.M410127200 |
0.499 |
|
| 2004 |
Kalia SK, Lee S, Smith PD, Liu L, Crocker SJ, Thorarinsdottir TE, Glover JR, Fon EA, Park DS, Lozano AM. BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. Neuron. 44: 931-45. PMID 15603737 DOI: 10.1016/J.Neuron.2004.11.026 |
0.729 |
|
| 2004 |
Cregan SP, Arbour NA, Maclaurin JG, Callaghan SM, Fortin A, Cheung EC, Guberman DS, Park DS, Slack RS. p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10003-12. PMID 15525786 DOI: 10.1523/Jneurosci.2114-04.2004 |
0.408 |
|
| 2004 |
Smith PD, O'Hare MJ, Park DS. CDKs: taking on a role as mediators of dopaminergic loss in Parkinson's disease. Trends in Molecular Medicine. 10: 445-51. PMID 15350897 DOI: 10.1016/J.Molmed.2004.07.003 |
0.428 |
|
| 2004 |
Fortin A, MacLaurin JG, Arbour N, Cregan SP, Kushwaha N, Callaghan SM, Park DS, Albert PR, Slack RS. The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1. The Journal of Biological Chemistry. 279: 28706-14. PMID 15105421 DOI: 10.1074/Jbc.M400376200 |
0.423 |
|
| 2004 |
Aleyasin H, Cregan SP, Iyirhiaro G, O'Hare MJ, Callaghan SM, Slack RS, Park DS. Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2963-73. PMID 15044535 DOI: 10.1523/Jneurosci.0155-04.2004 |
0.734 |
|
| 2004 |
Hayley S, Crocker SJ, Smith PD, Shree T, Jackson-Lewis V, Przedborski S, Mount M, Slack R, Anisman H, Park DS. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2045-53. PMID 14985447 DOI: 10.1523/Jneurosci.4564-03.2004 |
0.718 |
|
| 2004 |
Smith PD, O'Hare MJ, Park DS. Emerging pathogenic role for cyclin dependent kinases in neurodegeneration. Cell Cycle (Georgetown, Tex.). 3: 289-91. PMID 14726693 DOI: 10.4161/Cc.3.3.706 |
0.472 |
|
| 2003 |
Smith PD, Crocker SJ, Jackson-Lewis V, Jordan-Sciutto KL, Hayley S, Mount MP, O'Hare MJ, Callaghan S, Slack RS, Przedborski S, Anisman H, Park DS. Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 13650-5. PMID 14595022 DOI: 10.1073/Pnas.2232515100 |
0.744 |
|
| 2003 |
Keramaris E, Hirao A, Slack RS, Mak TW, Park DS. Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage. The Journal of Biological Chemistry. 278: 37782-9. PMID 12857758 DOI: 10.1074/jbc.M304049200 |
0.453 |
|
| 2003 |
Crocker SJ, Smith PD, Jackson-Lewis V, Lamba WR, Hayley SP, Grimm E, Callaghan SM, Slack RS, Melloni E, Przedborski S, Robertson GS, Anisman H, Merali Z, Park DS. Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4081-91. PMID 12764095 DOI: 10.1523/Jneurosci.23-10-04081.2003 |
0.784 |
|
| 2003 |
Sedarous M, Keramaris E, O'Hare M, Melloni E, Slack RS, Elce JS, Greer PA, Park DS. Calpains mediate p53 activation and neuronal death evoked by DNA damage. The Journal of Biological Chemistry. 278: 26031-8. PMID 12721303 DOI: 10.1074/Jbc.M302833200 |
0.411 |
|
| 2003 |
Crocker SJ, Liston P, Anisman H, Lee CJ, Smith PD, Earl N, Thompson CS, Park DS, Korneluk RG, Robertson GS. Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice. Neurobiology of Disease. 12: 150-61. PMID 12667469 DOI: 10.1016/S0969-9961(02)00020-7 |
0.779 |
|
| 2003 |
Rideout HJ, Wang Q, Park DS, Stefanis L. Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1237-45. PMID 12598612 DOI: 10.1523/Jneurosci.23-04-01237.2003 |
0.565 |
|
| 2002 |
Bhakar AL, Tannis LL, Zeindler C, Russo MP, Jobin C, Park DS, MacPherson S, Barker PA. Constitutive nuclear factor-kappa B activity is required for central neuron survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8466-75. PMID 12351721 |
0.337 |
|
| 2002 |
Hou ST, Xie X, Baggley A, Park DS, Chen G, Walker T. Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis. The Journal of Biological Chemistry. 277: 48764-70. PMID 12351630 DOI: 10.1074/jbc.M206336200 |
0.46 |
|
| 2002 |
O'Hare M, Wang F, Park DS. Cyclin-dependent kinases as potential targets to improve stroke outcome. Pharmacology & Therapeutics. 93: 135-43. PMID 12191606 DOI: 10.1016/S0163-7258(02)00183-3 |
0.458 |
|
| 2002 |
Cregan SP, Fortin A, MacLaurin JG, Callaghan SM, Cecconi F, Yu SW, Dawson TM, Dawson VL, Park DS, Kroemer G, Slack RS. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. The Journal of Cell Biology. 158: 507-17. PMID 12147675 DOI: 10.1083/Jcb.200202130 |
0.541 |
|
| 2002 |
Ferguson KL, Vanderluit JL, Hébert JM, McIntosh WC, Tibbo E, MacLaurin JG, Park DS, Wallace VA, Vooijs M, McConnell SK, Slack RS. Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. The Embo Journal. 21: 3337-46. PMID 12093735 DOI: 10.1093/Emboj/Cdf338 |
0.353 |
|
| 2002 |
Ghahremani MH, Keramaris E, Shree T, Xia Z, Davis RJ, Flavell R, Slack RS, Park DS. Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage. The Journal of Biological Chemistry. 277: 35586-96. PMID 12091388 DOI: 10.1074/Jbc.M204362200 |
0.508 |
|
| 2002 |
Wang F, Corbett D, Osuga H, Osuga S, Ikeda JE, Slack RS, Hogan MJ, Hakim AM, Park DS. Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 171-82. PMID 11823715 DOI: 10.1097/00004647-200202000-00005 |
0.414 |
|
| 2002 |
Bhakar AL, Tannis L, Zeindler C, Russo MP, Jobin C, Park DS, MacPherson S, Barker PA. Constitutive Nuclear Factor-κB Activity Is Required for Central Neuron Survival The Journal of Neuroscience. 22: 8466-8475. DOI: 10.1523/Jneurosci.22-19-08466.2002 |
0.445 |
|
| 2001 |
Wang F, O'Hare MJ, Park DS. Cyclin-dependent kinases and stroke. Expert Opinion On Therapeutic Targets. 5: 557-567. PMID 12540283 DOI: 10.1517/14728222.5.5.557 |
0.45 |
|
| 2001 |
Rideout HJ, Zang E, Yeasmin M, Gordon R, Jabado O, Park DS, Stefanis L. Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction Neuroscience. 107: 339-352. PMID 11731108 DOI: 10.1016/S0306-4522(01)00322-0 |
0.55 |
|
| 2001 |
Crocker SJ, Lamba WR, Smith PD, Callaghan SM, Slack RS, Anisman H, Park DS. c-Jun mediates axotomy-induced dopamine neuron death in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 13385-90. PMID 11687617 DOI: 10.1073/Pnas.231177098 |
0.732 |
|
| 2001 |
Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS, Hakim A, Albert PR, Cecconi F, Helin K, Park DS, Slack RS. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. The Journal of Cell Biology. 155: 207-16. PMID 11591730 DOI: 10.1083/Jcb.200105137 |
0.513 |
|
| 2001 |
Crocker SJ, Wigle N, Liston P, Thompson CS, Lee CJ, Xu D, Roy S, Nicholson DW, Park DS, MacKenzie A, Korneluk RG, Robertson GS. NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease. The European Journal of Neuroscience. 14: 391-400. PMID 11553289 DOI: 10.1046/J.0953-816X.2001.01653.X |
0.796 |
|
| 2001 |
Simpson MT, MacLaurin JG, Xu D, Ferguson KL, Vanderluit JL, Davoli MA, Roy S, Nicholson DW, Robertson GS, Park DS, Slack RS. Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7089-98. PMID 11549719 DOI: 10.1523/Jneurosci.21-18-07089.2001 |
0.671 |
|
| 2001 |
Simpson MTW, MacLaurin JG, Xu D, Ferguson KL, Vanderluit JL, Davoli MA, Roy S, Nicholson DW, Robertson GS, Park DS, Slack RS. Caspase 3 Deficiency Rescues Peripheral Nervous System Defect in Retinoblastoma Nullizygous Mice The Journal of Neuroscience. 21: 7089-7098. DOI: 10.1523/JNEUROSCI.21-18-07089.2001 |
0.471 |
|
| 2001 |
Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS. Cyclin-Dependent Kinases and P53 Pathways Are Activated Independently and Mediate Bax Activation in Neurons after DNA Damage The Journal of Neuroscience. 21: 5017-5026. DOI: 10.1523/Jneurosci.21-14-05017.2001 |
0.513 |
|
| 2000 |
Park DS, Obeidat A, Giovanni A, Greene LA. Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment. Neurobiology of Aging. 21: 771-81. PMID 11124421 DOI: 10.1016/S0197-4580(00)00220-7 |
0.647 |
|
| 2000 |
Osuga H, Osuga S, Wang F, Fetni R, Hogan MJ, Slack RS, Hakim AM, Ikeda JE, Park DS. Cyclin-dependent kinases as a therapeutic target for stroke. Proceedings of the National Academy of Sciences of the United States of America. 97: 10254-9. PMID 10944192 DOI: 10.1073/Pnas.170144197 |
0.507 |
|
| 2000 |
Cregan SP, MacLaurin J, Gendron TF, Callaghan SM, Park DS, Parks RJ, Graham FL, Morley P, Slack RS. Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons. Gene Therapy. 7: 1200-9. PMID 10918488 DOI: 10.1038/Sj.Gt.3301208 |
0.449 |
|
| 2000 |
Ferguson KL, Callaghan SM, O'Hare MJ, Park DS, Slack RS. The Rb-CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation. The Journal of Biological Chemistry. 275: 33593-600. PMID 10915795 DOI: 10.1074/Jbc.M004879200 |
0.436 |
|
| 2000 |
O'Hare MJ, Hou ST, Morris EJ, Cregan SP, Xu Q, Slack RS, Park DS. Induction and modulation of cerebellar granule neuron death by E2F-1. The Journal of Biological Chemistry. 275: 25358-64. PMID 10851232 DOI: 10.1074/Jbc.M001725200 |
0.511 |
|
| 2000 |
Keramaris E, Stefanis L, MacLaurin J, Harada N, Takaku K, Ishikawa T, Taketo MM, Robertson GS, Nicholson DW, Slack RS, Park DS. Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage. Molecular and Cellular Neurosciences. 15: 368-79. PMID 10845773 DOI: 10.1006/Mcne.2000.0838 |
0.675 |
|
| 2000 |
Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA. Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3104-14. PMID 10777774 DOI: 10.1523/Jneurosci.20-09-03104.2000 |
0.662 |
|
| 2000 |
Giovanni A, Keramaris E, Morris EJ, Hou ST, O'Hare M, Dyson N, Robertson GS, Slack RS, Park DS. E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. The Journal of Biological Chemistry. 275: 11553-60. PMID 10766769 DOI: 10.1074/Jbc.275.16.11553 |
0.684 |
|
| 1999 |
Maroney AC, Finn JP, Bozyczko-Coyne D, O'Kane TM, Neff NT, Tolkovsky AM, Park DS, Yan CY, Troy CM, Greene LA. CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults. Journal of Neurochemistry. 73: 1901-12. PMID 10537048 |
0.61 |
|
| 1999 |
Padmanabhan J, Park DS, Greene LA, Shelanski ML. Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8747-56. PMID 10516294 DOI: 10.1523/Jneurosci.19-20-08747.1999 |
0.614 |
|
| 1999 |
Cregan SP, MacLaurin JG, Craig CG, Robertson GS, Nicholson DW, Park DS, Slack RS. Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7860-9. PMID 10479688 DOI: 10.1523/Jneurosci.19-18-07860.1999 |
0.685 |
|
| 1999 |
Stefanis L, Park DS, Friedman WJ, Greene LA. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6235-47. PMID 10414953 DOI: 10.1523/Jneurosci.19-15-06235.1999 |
0.605 |
|
| 1999 |
Giovanni A, Wirtz-Brugger F, Keramaris E, Slack R, Park DS. Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death. The Journal of Biological Chemistry. 274: 19011-6. PMID 10383401 DOI: 10.1074/Jbc.274.27.19011 |
0.539 |
|
| 1999 |
Cregan SP, MacLaurin JG, Craig CG, Robertson GS, Nicholson DW, Park DS, Slack RS. Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons The Journal of Neuroscience. 19: 7860-7869. DOI: 10.1523/JNEUROSCI.19-18-07860.1999 |
0.608 |
|
| 1998 |
Park DS, Morris EJ, Padmanabhan J, Shelanski ML, Geller HM, Greene LA. Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents. The Journal of Cell Biology. 143: 457-67. PMID 9786955 DOI: 10.1083/Jcb.143.2.457 |
0.647 |
|
| 1998 |
Park DS, Morris EJ, Stefanis L, Troy CM, Shelanski ML, Geller HM, Greene LA. Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 830-40. PMID 9437005 DOI: 10.1523/Jneurosci.18-03-00830.1998 |
0.639 |
|
| 1997 |
Park DS, Stefanis L, Greene LA. Ordering the multiple pathways of apoptosis. Trends in Cardiovascular Medicine. 7: 294-301. PMID 21235899 DOI: 10.1016/S1050-1738(97)00090-X |
0.546 |
|
| 1997 |
Park DS, Levine B, Ferrari G, Greene LA. Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8975-83. PMID 9364045 DOI: 10.1523/Jneurosci.17-23-08975.1997 |
0.659 |
|
| 1997 |
Park DS, Morris EJ, Greene LA, Geller HM. G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1256-70. PMID 9006970 DOI: 10.1523/Jneurosci.17-04-01256.1997 |
0.642 |
|
| 1996 |
Stefanis L, Park DS, Yan CY, Farinelli SE, Troy CM, Shelanski ML, Greene LA. Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis. The Journal of Biological Chemistry. 271: 30663-71. PMID 8940042 DOI: 10.1074/Jbc.271.48.30663 |
0.563 |
|
| 1996 |
Park DS, Stefanis L, Yan CY, Farinelli SE, Greene LA. Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells. The Journal of Biological Chemistry. 271: 21898-905. PMID 8702992 DOI: 10.1074/Jbc.271.36.21898 |
0.557 |
|
| 1996 |
Park DS, Farinelli SE, Greene LA. Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons. The Journal of Biological Chemistry. 271: 8161-9. PMID 8626506 DOI: 10.1074/Jbc.271.14.8161 |
0.627 |
|
| 1996 |
Farinelli SE, Park DS, Greene LA. Nitric oxide delays the death of trophic factor-deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2325-34. PMID 8601812 DOI: 10.1523/Jneurosci.16-07-02325.1996 |
0.628 |
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