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Stephen N. Floor - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
RNA, molecular biology, cell biology, biochemistry, systems biology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jowhar Z, Xu A, Venkataramanan S, Dossena F, Hoye ML, Silver DL, Floor SN, Calviello L. A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X. Molecular Systems Biology. PMID 38273160 DOI: 10.1038/s44320-024-00013-0  0.31
2023 Wilkins KC, Schroeder T, Gu S, Revalde JL, Floor SN. Determinants of DDX3X sensitivity uncovered using a helicase activity in translation reporter. Biorxiv : the Preprint Server For Biology. PMID 37745530 DOI: 10.1101/2023.09.14.557805  0.307
2023 Jowhar Z, Xu A, Venkataramanan S, Hoye ML, Silver DL, Floor SN, Calviello L. A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X. Biorxiv : the Preprint Server For Biology. PMID 37214951 DOI: 10.1101/2023.05.11.540322  0.31
2022 Wilkins KC, Venkataramanan S, Floor SN. Lysate and cell-based assays to probe the translational role of RNA helicases. Methods in Enzymology. 673: 141-168. PMID 35965005 DOI: 10.1016/bs.mie.2022.03.032  0.304
2021 Calviello L, Venkataramanan S, Rogowski KJ, Wyler E, Wilkins K, Tejura M, Thai B, Krol J, Filipowicz W, Landthaler M, Floor SN. DDX3 depletion represses translation of mRNAs with complex 5' UTRs. Nucleic Acids Research. 49: 5336-5350. PMID 33905506 DOI: 10.1093/nar/gkab287  0.343
2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, ... ... Floor S, et al. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. Biorxiv : the Preprint Server For Biology. PMID 32511329 DOI: 10.1101/2020.03.22.002386  0.534
2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, ... ... Floor SN, et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. PMID 32353859 DOI: 10.1038/S41586-020-2286-9  0.588
2020 Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bézieau S, ... ... Floor SN, et al. Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. PMID 32135084 DOI: 10.1016/J.Neuron.2020.01.042  0.316
2019 Arake de Tacca LM, Pulos-Holmes MC, Floor SN, Cate JHD. mRNA isoforms and regulation of their translation. Rna (New York, N.Y.). PMID 31263002 DOI: 10.1261/Rna.070193.118  0.43
2018 Iwasaki S, Iwasaki W, Takahashi M, Sakamoto A, Watanabe C, Shichino Y, Floor SN, Fujiwara K, Mito M, Dodo K, Sodeoka M, Imataka H, Honma T, Fukuzawa K, Ito T, et al. The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Molecular Cell. PMID 30595437 DOI: 10.1016/J.Molcel.2018.11.026  0.375
2017 Blair JD, Hockemeyer D, Doudna JA, Bateup HS, Floor SN. Widespread Translational Remodeling during Human Neuronal Differentiation. Cell Reports. 21: 2005-2016. PMID 29141229 DOI: 10.1016/J.Celrep.2017.10.095  0.526
2017 Staahl BT, Benekareddy M, Coulon-Bainier C, Banfal AA, Floor SN, Sabo JK, Urnes C, Munares GA, Ghosh A, Doudna JA. Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes. Nature Biotechnology. PMID 28191903 DOI: 10.1038/Nbt.3806  0.708
2016 Iwasaki S, Floor SN, Ingolia NT. Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor. Nature. PMID 27309803 DOI: 10.1038/Nature17978  0.401
2016 Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/Oncotarget.8612  0.573
2016 Floor SN, Doudna JA. Tunable protein synthesis by transcript isoforms in human cells. Elife. 5. PMID 26735365 DOI: 10.7554/Elife.10921  0.548
2016 Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA. Analog sensitive chemical inhibition of the DEAD-box protein DDX3. Protein Science : a Publication of the Protein Society. 25: 638-49. PMID 26650549 DOI: 10.1002/Pro.2857  0.559
2016 Floor SN, Condon KJ, Sharma D, Jankowsky E, Doudna JA. Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3. The Journal of Biological Chemistry. 291: 2412-21. PMID 26598523 DOI: 10.1074/Jbc.M115.700625  0.582
2015 Floor SN, Doudna JA. Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome. Molecular Cell. 60: 712-4. PMID 26638173 DOI: 10.1016/J.Molcel.2015.11.014  0.473
2015 Floor SN, Doudna JA. Author response: Tunable protein synthesis by transcript isoforms in human cells Elife. DOI: 10.7554/Elife.10921.030  0.487
2014 Condon K, Floor S, Doudna J. Engineering Inhibitor Specificity in the Dead-Box Protein Family Biophysical Journal. 106: 495a-496a. DOI: 10.1016/J.Bpj.2013.11.2772  0.556
2013 Aglietti RA, Floor SN, McClendon CL, Jacobson MP, Gross JD. Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2. Structure (London, England : 1993). 21: 1571-80. PMID 23911090 DOI: 10.1016/J.Str.2013.06.021  0.717
2012 Floor SN, Borja MS, Gross JD. Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan Proceedings of the National Academy of Sciences of the United States of America. 109: 2872-2877. PMID 22323607 DOI: 10.1073/Pnas.1113620109  0.769
2010 Floor SN, Jones BN, Hernandez GA, Gross JD. A split active site couples cap recognition by Dcp2 to activation. Nature Structural & Molecular Biology. 17: 1096-101. PMID 20711189 DOI: 10.1038/Nsmb.1879  0.749
2008 Neher SB, Bradshaw N, Floor SN, Gross JD, Walter P. SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction. Nature Structural & Molecular Biology. 15: 916-23. PMID 19172744 DOI: 10.1038/Nsmb.1467  0.632
2008 Lampe JN, Floor SN, Gross JD, Nishida CR, Jiang Y, Trnka MJ, Ortiz de Montellano PR. Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine. Journal of the American Chemical Society. 130: 16168-9. PMID 18998650 DOI: 10.1021/Ja8071463  0.625
2008 Floor SN, Jones BN, Gross JD. Control of mRNA decapping by Dcp2: An open and shut case? Rna Biology. 5: 189-192. PMID 18971632 DOI: 10.4161/Rna.6859  0.747
2008 Deshmukh MV, Jones BN, Quang-Dang DU, Flinders J, Floor SN, Kim C, Jemielity J, Kalek M, Darzynkiewicz E, Gross JD. mRNA decapping is promoted by an RNA-binding channel in Dcp2. Molecular Cell. 29: 324-36. PMID 18280238 DOI: 10.1016/J.Molcel.2007.11.027  0.749
2004 Floor SN, Melott AL, Motl PM. Simulated versus observed cluster eccentricity evolution Astrophysical Journal. 611: 153-157. DOI: 10.1086/422090  0.506
2003 Floor SN, Melott AL, Miller CJ, Bryan GL. Eccentricity evolution in simulated galaxy clusters Astrophysical Journal. 591: 741-748. DOI: 10.1086/375493  0.5
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