Fujie Tanaka, Ph.D. - Publications

Affiliations: 
Institute for Chemical Research Kyoto University, Kyōto-shi, Kyōto-fu, Japan 

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen KL, Tanaka F. Organocatalytic enantioselective Mannich and retro-Mannich reactions and combinations of these reactions to afford tetrasubstituted α-amino acid derivatives. Organic & Biomolecular Chemistry. 22: 477-481. PMID 38099926 DOI: 10.1039/d3ob01855e  0.393
2023 Garg Y, Osborne J, Vasylevskyi S, Velmurugan N, Tanaka F. 1,3-Diamine-Derived Catalysts: Design, Synthesis, and the Use in Enantioselective Mannich Reactions of Ketones. The Journal of Organic Chemistry. PMID 37460110 DOI: 10.1021/acs.joc.3c01051  0.456
2023 Sohail M, Tanaka F. Limiting the Loading of Reactant 1,3-Cyclohexanedione Enables the Use of Less Catalyst. The Journal of Organic Chemistry. PMID 37403968 DOI: 10.1021/acs.joc.3c00838  0.372
2022 Tanaka F. Amines as Catalysts: Dynamic Features and Kinetic Control of Catalytic Asymmetric Chemical Transformations to Form C-C Bonds and Complex Molecules. Chemical Record (New York, N.Y.). e202200207. PMID 36202628 DOI: 10.1002/tcr.202200207  0.355
2022 Aher RD, Ishikawa A, Yamanaka M, Tanaka F. Catalytic Enantioselective Construction of Decalin Derivatives by Dynamic Kinetic Desymmetrization of C2-Symmetric Derivatives through Aldol-Aldol Annulation. The Journal of Organic Chemistry. 87: 8151-8157. PMID 35666096 DOI: 10.1021/acs.joc.2c00889  0.412
2022 Mondal S, Aher RD, Bethi V, Lin YJ, Taniguchi T, Monde K, Tanaka F. Control of Reactions of Pyruvates by Catalysts: Direct Enantioselective Mannich Reactions of Pyruvates Catalyzed by Amine-based Catalyst Systems. Organic Letters. PMID 35226512 DOI: 10.1021/acs.orglett.2c00436  0.737
2021 Fujioka T, Numoto N, Akama H, Shilpa K, Oka M, Roy PK, Krishna Y, Ito N, Baker D, Oda M, Tanaka F. Varying the Directionality of Protein Catalysts for Aldol and Retro-aldol Reactions. Chembiochem : a European Journal of Chemical Biology. PMID 34698422 DOI: 10.1002/cbic.202100435  0.387
2021 Pasha M, Tanaka F. Organocatalytic diastereo- and enantioselective oxa-hetero-Diels-Alder reactions of enones with aryl trifluoromethyl ketones for the synthesis of trifluoromethyl-substituted tetrahydropyrans. Organic & Biomolecular Chemistry. 19: 9242-9250. PMID 34661230 DOI: 10.1039/d1ob01844b  0.457
2021 Tanaka F, Sohail M. Dynamic Kinetic Asymmetric Transformation of Racemic Diastereomers: Diastereo- and Enantioconvergent Michael-Henry Reactions to Afford Spirooxindoles Bearing Furan-Fused Rings. Angewandte Chemie (International Ed. in English). PMID 34236757 DOI: 10.1002/anie.202108734  0.379
2021 Krishna Y, Tanaka F. Intramolecular Formal [4 + 2] Cycloadditions: Synthesis of Spiro Isoindolinone Derivatives and Related Molecules. Organic Letters. PMID 33601884 DOI: 10.1021/acs.orglett.1c00283  0.348
2020 Garg Y, Tanaka F. Enantioselective Direct -Selective Mannich-type Reactions Catalyzed by 3-Pyrrolidinecarboxylic Acid in the Presence of Potassium Carbonate: Addition of Potassium Carbonate Improves Enantioselectivities. Organic Letters. PMID 32428413 DOI: 10.1021/Acs.Orglett.0C01561  0.538
2020 Maram L, Tanaka F. Switching Electrophile Intermediates to Nucleophiles: Michael and Oxa-Diels-Alder Reactions to Afford Polyoxy-Functionalized Piperidine Derivatives with Tetrasubstituted Carbon. Organic Letters. PMID 32193936 DOI: 10.1021/Acs.Orglett.0C00735  0.439
2020 Tanaka F, Pasha M, Sohail M. Intramolecular Oxa-Michael Reactions of Aldols Generated from Enones and Isatins to Afford Spirooxindole Tetrahydropyrans Heterocycles. 101: 339. DOI: 10.3987/Com-19-S(F)26  0.512
2019 Zhang D, Chen Y, Cai H, Yin L, Zhong J, Man J, Zhang QF, Bethi V, Tanaka F. Direct Catalytic Asymmetric Synthesis of Oxindole-Derived δ-Hydroxy-β-ketoesters by Aldol Reactions. Organic Letters. PMID 31746616 DOI: 10.1021/Acs.Orglett.9B03527  0.484
2019 Sohail M, Tanaka F. Control of Chemical Reactions Using Molecules that Buffer Non-aqueous Solutions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31646678 DOI: 10.1002/Chem.201903552  0.407
2019 Krishna Y, Shilpa K, Tanaka F. Intramolecular Mannich and Michael Annulation Reactions of Lactam Derivatives Bearing Enals To Afford Bicyclic N-Heterocycles. Organic Letters. PMID 31584286 DOI: 10.1021/Acs.Orglett.9B03210  0.489
2019 Maram L, Tanaka F. Mannich Reactions of Carbohydrate Derivatives with Ketones To Afford Polyoxy-Functionalized Piperidines. Organic Letters. PMID 30693778 DOI: 10.1021/Acs.Orglett.9B00105  0.504
2019 Tanaka F, Enukonda J, Johnson S. C-Glycosidation of Unprotected Aldopentoses with Ketones Using Proline-Triethylamine as Catalyst Heterocycles. 99: 633. DOI: 10.3987/Com-18-S(F)13  0.336
2019 Sohail M, Tanaka F. Dynamic stereoselective annulation via aldol-oxa-cyclization cascade reaction to afford spirooxindole pyran polycycles Communications Chemistry. 2. DOI: 10.1038/s42004-019-0177-5  0.369
2019 Sohail M, Tanaka F. Cover Feature: Control of Chemical Reactions by Using Molecules that Buffer Non‐aqueous Solutions (Chem. Eur. J. 1/2020) Chemistry – a European Journal. 26: 4-4. DOI: 10.1002/Chem.201904861  0.347
2018 Chouthaiwale PV, Aher RD, Tanaka F. Catalytic Enantioselective Formal (4+2) Cycloaddition by Aldol-Aldol Annulation of Pyruvate Derivatives with Cyclohexane-1,3-Diones to Afford Functionalized Decalins. Angewandte Chemie (International Ed. in English). PMID 30125444 DOI: 10.1002/Anie.201808219  0.509
2018 Yin F, Garifullina A, Tanaka F. Correction: Synthesis of pyrrolidine-3-carboxylic acid derivatives via asymmetric Michael addition reactions of carboxylate-substituted enones. Organic & Biomolecular Chemistry. PMID 29651476 DOI: 10.1039/c8ob90051e  0.357
2018 Johnson S, Bagdi AK, Tanaka F. C-Glycosidation of Unprotected Di- and Trisaccharide Aldopyranoses with Ketones Using Pyrrolidine-Boric Acid Catalysis. The Journal of Organic Chemistry. PMID 29595968 DOI: 10.1021/Acs.Joc.8B00340  0.353
2018 Tanaka F, V. Chouthaiwale P, D. Aher R. Reactions of Pyruvate-Derived Dihydropyrans with Formaldehyde: Synthesis of Functionalized Furopyrans and Related Products Heterocycles. 97: 569. DOI: 10.3987/Com-18-S(T)29  0.454
2018 Zhang D, Chuang P, Cao D, Krishna Y, Shilpa K, Tanaka F. Detection of enantiomers of chiral primary amines by 1H NMR analysis via enamine formation with an enantiopure γ-position aldol product of a β-keto ester Tetrahedron Letters. 59: 2248-2250. DOI: 10.1016/J.Tetlet.2018.04.079  0.352
2017 Yin F, Garifullina A, Tanaka F. Synthesis of pyrrolidine-3-carboxylic acid derivatives via asymmetric Michael addition reactions of carboxylate-substituted enones. Organic & Biomolecular Chemistry. PMID 28686271 DOI: 10.1039/C7Ob01484H  0.513
2017 Zhang D, Tanaka F. Determination of Relative Frequency of Carbanion Formation at α-Positions of Ketones under Aldol Reaction Catalysis Conditions. Organic Letters. PMID 28671473 DOI: 10.1021/Acs.Orglett.7B01676  0.485
2017 Huang JR, Sohail M, Taniguchi T, Monde K, Tanaka F. Formal (4+1) Cycloaddition and Enantioselective Michael-Henry Cascade Reactions To Synthesize Spiro[4,5]decanes and Spirooxindole Polycycles. Angewandte Chemie (International Ed. in English). PMID 28397989 DOI: 10.1002/Anie.201701049  0.49
2016 Kobayashi K, Ohshiro T, Tomoda H, Yin F, Cui HL, Chouthaiwale PV, Tanaka F. Discovery of SOAT2 inhibitors from synthetic small molecules. Bioorganic & Medicinal Chemistry Letters. PMID 27876317 DOI: 10.1016/J.Bmcl.2016.11.008  0.327
2016 Cui HL, Chouthaiwale PV, Yin F, Tanaka F. Catalytic asymmetric hetero-Diels-Alder reactions of enones with isatins to access functionalized spirooxindole tetrahydropyrans: scope, derivatization, and discovery of bioactives. Organic & Biomolecular Chemistry. PMID 26750767 DOI: 10.1039/C5Ob02393A  0.503
2016 Zhang D, Tanaka F. Catalytic enantioselective oxa-hetero-Diels–Alder reactions of enones with aryl trifluoromethyl ketones Rsc Advances. 6: 61454-61457. DOI: 10.1039/C6Ra13859D  0.535
2016 Cui HL, Chouthaiwale PV, Yin F, Tanaka F. Reaction-Based Mechanistic Investigations of Asymmetric Hetero-Diels-Alder Reactions of Enones with Isatins Catalyzed by Amine-Based Three-Component Catalyst Systems Asian Journal of Organic Chemistry. 5: 153-161. DOI: 10.1002/Ajoc.201500412  0.515
2015 Johnson S, Tanaka F. Direct synthesis of C-glycosides from unprotected 2-N-acyl-aldohexoses via aldol condensation-oxa-Michael reactions with unactivated ketones. Organic & Biomolecular Chemistry. PMID 26565955 DOI: 10.1039/C5Ob02094H  0.391
2015 Jithender E, Katsuyama I, Zhang D, Johnson S, Tanaka F. Aldol reactions of 1,2-diketones catalyzed by amines to afford furanose derivatives Tetrahedron Letters. 56: 735-738. DOI: 10.1016/J.Tetlet.2014.12.094  0.537
2015 Cui H, Chouthaiwale PV, Yin F, Tanaka F. Inside Cover: Reaction-Based Mechanistic Investigations of Asymmetric Hetero-Diels-Alder Reactions of Enones with Isatins Catalyzed by Amine-Based Three-Component Catalyst Systems (Asian J. Org. Chem. 1/2016) Asian Journal of Organic Chemistry. 5: 2-2. DOI: 10.1002/Ajoc.201500503  0.511
2015 Zhang D, Tanaka F. Aldol Reactions of Ketone Donors with Aryl Trifluoromethyl Ketone Acceptors Catalyzed by 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) for Concise Access to Aryl- and Trifluoromethyl- Substituted Tertiary Alcohols Advanced Synthesis and Catalysis. 357: 3458-3462. DOI: 10.1002/Adsc.201500497  0.482
2014 Chouthaiwale PV, Tanaka F. Reactions of pyruvates: organocatalytic synthesis of functionalized dihydropyrans in one pot and further transformations to functionalized carbocycles and heterocycles. Chemical Communications (Cambridge, England). 50: 14881-4. PMID 25325901 DOI: 10.1039/C4Cc06035K  0.446
2014 Cui HL, Tanaka F. One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis. Organic & Biomolecular Chemistry. 12: 5822-6. PMID 24972009 DOI: 10.1039/C4Ob01019A  0.398
2014 Mase N, Ando T, Shibagaki F, Sugita A, Narumi T, Toda M, Watanabe N, Tanaka F. Fluorogenic aldehydes bearing arylethynyl groups: Turn-on aldol reaction sensors for evaluation of organocatalysis in DMSO Tetrahedron Letters. 55: 1946-1948. DOI: 10.1016/J.Tetlet.2014.02.007  0.69
2014 Katsuyama I, Chouthaiwale PV, Akama H, Cui HL, Tanaka F. Fluorogenic probes for aldol reactions: Tuning of fluorescence using π-conjugation systems Tetrahedron Letters. 55: 74-78. DOI: 10.1016/J.Tetlet.2013.10.122  0.494
2014 Zhang D, Johnson S, Cui HL, Tanaka F. Synthesis of furanose spirooxindoles via 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)-catalyzed aldol reactions of a pyruvic aldehyde derivative Asian Journal of Organic Chemistry. 3: 391-394. DOI: 10.1002/Ajoc.201400016  0.479
2013 Cui HL, Tanaka F. Catalytic enantioselective formal hetero-Diels-Alder reactions of enones with isatins to give spirooxindole tetrahydropyranones. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 6213-6. PMID 23559482 DOI: 10.1002/Chem.201300595  0.492
2013 Mase N, Takabe K, Tanaka F. Erratum to “Fluorogenic probes for chemical transformations: 9-anthracene derivatives for monitoring reaction progress by an increase in fluorescence” [Tetrahedron Lett. 54 (2013) 4306–4308] Tetrahedron Letters. 54: 5140. DOI: 10.1016/J.Tetlet.2013.07.086  0.642
2013 Mase N, Takabe K, Tanaka F. Fluorogenic probes for chemical transformations: 9-anthracene derivatives for monitoring reaction progress by an increase in fluorescence Tetrahedron Letters. 54: 4306-4308. DOI: 10.1016/J.Tetlet.2013.06.010  0.657
2013 Katsuyama I, Chouthaiwale PV, Cui HL, Ito Y, Sando A, Tokiwa H, Tanaka F. Substituent-dependent reactivity in aldehyde transformations: 4-(phenylethynyl)benzaldehydes versus simple benzaldehydes Tetrahedron. 69: 4098-4104. DOI: 10.1016/J.Tet.2013.03.056  0.487
2009 Zhu X, Tanaka F, Lerner RA, Barbas CF, Wilson IA. Direct observation of an enamine intermediate in amine catalysis. Journal of the American Chemical Society. 131: 18206-7. PMID 19968282 DOI: 10.1021/Ja907271A  0.571
2009 Guo HM, Tanaka F. A fluorogenic aldehyde bearing a 1,2,3-triazole moiety for monitoring the progress of aldol reactions. The Journal of Organic Chemistry. 74: 2417-24. PMID 19222210 DOI: 10.1021/Jo900013W  0.502
2009 Tanaka F. Enamine-Based Reactions: Strategies for the Development of Organocatalysts and Catalyzed Reactions Journal of the Society of Japanese Women Scientists. 10: 1-9. DOI: 10.5939/sjws.09001  0.408
2008 Minakawa M, Guo HM, Tanaka F. Imines that react with phenols in water over a wide pH range. The Journal of Organic Chemistry. 73: 8669-72. PMID 18844415 DOI: 10.1021/Jo8017389  0.339
2008 Tanaka F, Hu Y, Sutton J, Asawapornmongkol L, Fuller R, Olson AJ, Barbas CF, Lerner RA. Selection of phage-displayed peptides that bind to a particular ligand-bound antibody. Bioorganic & Medicinal Chemistry. 16: 5926-31. PMID 18472269 DOI: 10.1016/J.Bmc.2008.04.062  0.476
2008 Guo HM, Minakawa M, Tanaka F. Fluorogenic imines for fluorescent detection of Mannich-type reactions of phenols in water. The Journal of Organic Chemistry. 73: 3964-6. PMID 18429632 DOI: 10.1021/Jo8003293  0.414
2008 Jiang L, Althoff EA, Clemente FR, Doyle L, Röthlisberger D, Zanghellini A, Gallaher JL, Betker JL, Tanaka F, Barbas CF, Hilvert D, Houk KN, Stoddard BL, Baker D. De novo computational design of retro-aldol enzymes. Science (New York, N.Y.). 319: 1387-91. PMID 18323453 DOI: 10.1126/Science.1152692  0.328
2008 Zhang H, Mitsumori S, Utsumi N, Imai M, Garcia-Delgado N, Mifsud M, Albertshofer K, Cheong PH, Houk KN, Tanaka F, Barbas CF. Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-Mannich-type reactions: importance of the 3-acid group on pyrrolidine for stereocontrol. Journal of the American Chemical Society. 130: 875-86. PMID 18163619 DOI: 10.1021/Ja074907+  0.5
2008 Zhang H, Ramasastry SSV, Tanaka F, Barbas CF. Organocatalytic anti-Mannich reactions with dihydroxyacetone and acyclic dihydroxyacetone derivatives: A facile route to amino sugars Advanced Synthesis and Catalysis. 350: 791-796. DOI: 10.1002/Adsc.200800069  0.728
2007 Hayashi I, Mizuno H, Tong KI, Furuta T, Tanaka F, Yoshimura M, Miyawaki A, Ikura M. Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede. Journal of Molecular Biology. 372: 918-26. PMID 17692334 DOI: 10.1016/J.Jmb.2007.06.037  0.338
2007 Utsumi N, Imai M, Tanaka F, Ramasastry SS, Barbas CF. Mimicking aldolases through organocatalysis: syn-selective aldol reactions with protected dihydroxyacetone. Organic Letters. 9: 3445-8. PMID 17645352 DOI: 10.1021/Ol701467S  0.737
2007 Ramasastry SS, Albertshofer K, Utsumi N, Tanaka F, Barbas CF. Mimicking fructose and rhamnulose aldolases: organocatalytic syn-aldol reactions with unprotected dihydroxyacetone. Angewandte Chemie (International Ed. in English). 46: 5572-5. PMID 17577894 DOI: 10.1002/Anie.200701269  0.728
2007 Tanaka F, Jones T, Kubitz D, Lerner RA. Anti-formyl peptide antibodies. Bioorganic & Medicinal Chemistry Letters. 17: 1943-5. PMID 17293112 DOI: 10.1016/J.Bmcl.2007.01.082  0.472
2007 Ramasastry SS, Zhang H, Tanaka F, Barbas CF. Direct catalytic asymmetric synthesis of anti-1,2-amino alcohols and syn-1,2-diols through organocatalytic anti-Mannich and syn-aldol reactions. Journal of the American Chemical Society. 129: 288-9. PMID 17212404 DOI: 10.1021/Ja0677012  0.713
2007 Utsumi N, Imai M, Tanaka F, Ramasastry SSV, Barbas CF. syn-Selective Organocatalytic Aldol Reactions of Dihydroxyacetone Equivalents Synfacts. 2007: 1100-1100. DOI: 10.1055/S-2007-969002  0.488
2007 III C, Ramasastry S, Zhang H, Tanaka F. Organocatalytic anti-Mannich and syn-Aldol Reactions of α-Hydroxy Ketones Synfacts. 2007: 0325-0325. DOI: 10.1055/S-2007-968235  0.705
2007 Albertshofer K, Thayumanavan R, Utsumi N, Tanaka F, Barbas CF. Amine-catalyzed Michael reactions of an aminoaldehyde derivative to nitroolefins Tetrahedron Letters. 48: 693-696. DOI: 10.1016/J.Tetlet.2006.11.096  0.497
2007 Tanaka F, Barbas CF. Enamine Catalysis: Aldol and Mannich-Type Reactions Enantioselective Organocatalysis: Reactions and Experimental Procedures. 19-55. DOI: 10.1002/9783527610945.ch2a  0.369
2006 Zhang H, Mifsud M, Tanaka F, Barbas CF. 3-Pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones. Journal of the American Chemical Society. 128: 9630-1. PMID 16866507 DOI: 10.1021/ja062950b  0.451
2006 Chowdari NS, Ahmad M, Albertshofer K, Tanaka F, Barbas CF. Expedient synthesis of chiral 1,2- and 1,4-diamines: protecting group dependent regioselectivity in direct organocatalytic asymmetric Mannich reactions. Organic Letters. 8: 2839-42. PMID 16774270 DOI: 10.1021/ol060980d  0.459
2006 Suri JT, Mitsumori S, Albertshofer K, Tanaka F, Barbas CF. Dihydroxyacetone variants in the organocatalytic construction of carbohydrates: mimicking tagatose and fuculose aldolases. The Journal of Organic Chemistry. 71: 3822-8. PMID 16674055 DOI: 10.1021/Jo0602017  0.768
2006 Mase N, Watanabe K, Yoda H, Takabe K, Tanaka F, Barbas CF. Organocatalytic direct michael reaction of ketones and aldehydes with beta-nitrostyrene in brine. Journal of the American Chemical Society. 128: 4966-7. PMID 16608326 DOI: 10.1021/Ja060338E  0.71
2006 Cheong PH, Zhang H, Thayumanavan R, Tanaka F, Houk KN, Barbas CF. Pipecolic acid-catalyzed direct asymmetric mannich reactions. Organic Letters. 8: 811-4. PMID 16494447 DOI: 10.1021/Ol052861O  0.49
2006 Mitsumori S, Zhang H, Cheong PHY, Houk KN, Tanaka F, Barbas CF. Direct asymmetric anti-Mannich-type reactions catalyzed by a designed amino acid Journal of the American Chemical Society. 128: 1040-1041. PMID 16433496 DOI: 10.1021/Ja056984F  0.544
2006 Mase N, Nakai Y, Ohara N, Yoda H, Takabe K, Tanaka F, Barbas CF. Organocatalytic direct asymmetric aldol reactions in water. Journal of the American Chemical Society. 128: 734-5. PMID 16417359 DOI: 10.1021/Ja0573312  0.695
2006 Tanaka F, Barbas, III C, Zhang H, Mifsud M. Organocatalytic anti-Mannich Reaction of Ketones Synfacts. 2006: 0956-0956. DOI: 10.1055/S-2006-949232  0.504
2005 Tanaka F. Development of protein, peptide, and small molecule catalysts using catalysis-based selection strategies. Chemical Record (New York, N.Y.). 5: 276-85. PMID 16211623 DOI: 10.1002/Tcr.20051  0.534
2005 Tanaka F, Fuller R, Barbas CF. Development of small designer aldolase enzymes: catalytic activity, folding, and substrate specificity. Biochemistry. 44: 7583-92. PMID 15896002 DOI: 10.1021/Bi050216J  0.439
2005 Tanaka F, Barbas CF. Enamine-based Reactions Using Organocatalysts Journal of Synthetic Organic Chemistry Japan. 63: 709-721. DOI: 10.5059/Yukigoseikyokaishi.63.709  0.557
2005 Tanaka F, Barbas CF. Enamine-based reactions using organocatalysts: From aldolase antibodies to small amino acid and amine catalysts Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 63: 709-721.  0.405
2004 Zhu X, Tanaka F, Hu Y, Heine A, Fuller R, Zhong G, Olson AJ, Lerner RA, Barbas CF, Wilson IA. The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis. Journal of Molecular Biology. 343: 1269-80. PMID 15491612 DOI: 10.1016/J.Jmb.2004.08.102  0.676
2004 Thayumanavan R, Tanaka F, Barbas III CF. Direct organocatalytic asymmetric aldol reactions of alpha-amino aldehydes: expedient syntheses of highly enantiomerically enriched anti-beta-hydroxy-alpha-amino acids. Organic Letters. 6: 3541-4. PMID 15387543 DOI: 10.1021/ol0485417  0.32
2004 Sinha SC, Li LS, Watanabe S, Kaltgrad E, Tanaka F, Rader C, Lerner RA, Barbas CF. Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 5467-72. PMID 15378729 DOI: 10.1002/Chem.200400419  0.603
2004 Notz W, Tanaka F, Barbas CF. Enamine-based organocatalysis with proline and diamines: the development of direct catalytic asymmetric Aldol, Mannich, Michael, and Diels-alder reactions. Accounts of Chemical Research. 37: 580-91. PMID 15311957 DOI: 10.1021/Ar0300468  0.421
2004 Tanaka F, Mase N, Barbas CF. Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde. Chemical Communications (Cambridge, England). 1762-3. PMID 15278174 DOI: 10.1039/B405642F  0.612
2004 Mase N, Thayumanavan R, Tanaka F, Barbas CF. Direct asymmetric organocatalytic Michael reactions of alpha,alpha-disubstituted aldehydes with beta-nitrostyrenes for the synthesis of quaternary carbon-containing products. Organic Letters. 6: 2527-30. PMID 15255682 DOI: 10.1021/Ol049196O  0.663
2004 Tanaka F, Flores F, Kubitz D, Lerner RA, Barbas CF. Antibody-catalyzed aminolysis of a chloropyrimidine derivative. Chemical Communications (Cambridge, England). 1242-3. PMID 15136858 DOI: 10.1039/B403672G  0.59
2004 Mase N, Tanaka F, Barbas CF. Synthesis of beta-hydroxyaldehydes with stereogenic quaternary carbon centers by direct organocatalytic asymmetric aldol reactions. Angewandte Chemie (International Ed. in English). 43: 2420-3. PMID 15114579 DOI: 10.1002/Anie.200353546  0.639
2004 Tanaka F, Mase N, Barbas CF. Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations. Journal of the American Chemical Society. 126: 3692-3. PMID 15038704 DOI: 10.1021/Ja049641A  0.696
2004 Tanaka F, Fuller R, Shim H, Lerner RA, Barbas CF. Evolution of aldolase antibodies in vitro: correlation of catalytic activity and reaction-based selection. Journal of Molecular Biology. 335: 1007-18. PMID 14698295 DOI: 10.1016/J.Jmb.2003.11.014  0.672
2004 Betancort JM, Sakthivel K, Thayumanavan R, Tanaka F, Barbas CF. Catalytic direct asymmetric Michael reactions: Addition of unmodified ketone and aldehyde donors to alkylidene malonates and nitro olefins Synthesis. 1509-1521. DOI: 10.1055/S-2004-822392  0.552
2004 Tanaka F, Thayumanavan R, Mase N, Barbas CF. Rapid analysis of solvent effects on enamine formation by fluorescence: How might enzymes facilitate enamine chemistry with primary amines? Tetrahedron Letters. 45: 325-328. DOI: 10.1016/J.Tetlet.2003.10.157  0.655
2004 Notz W, Watanabe SI, Chowdari NS, Zhong G, Betancort JM, Tanaka F, Barbas CF. The scope of the direct proline-catalyzed asymmetric addition of ketones to imines Advanced Synthesis and Catalysis. 346: 1131-1140. DOI: 10.1002/Adsc.200404114  0.629
2003 Notz W, Tanaka F, Watanabe S, Chowdari NS, Turner JM, Thayumanavan R, Barbas CF. The direct organocatalytic asymmetric mannich reaction: unmodified aldehydes as nucleophiles. The Journal of Organic Chemistry. 68: 9624-34. PMID 14656087 DOI: 10.1021/Jo0347359  0.507
2003 Mase N, Tanaka F, Barbas CF. Rapid fluorescent screening for bifunctional amine-acid catalysts: efficient syntheses of quaternary carbon-containing aldols under organocatalysis. Organic Letters. 5: 4369-72. PMID 14602002 DOI: 10.1021/ol035651p  0.629
2003 Tanaka F, Thayumanavan R, Barbas CF. Fluorescent detection of carbon-carbon bond formation. Journal of the American Chemical Society. 125: 8523-8. PMID 12848558 DOI: 10.1021/Ja034069T  0.44
2002 Tanaka F. Catalytic antibodies as designer proteases and esterases. Chemical Reviews. 102: 4885-906. PMID 12475210 DOI: 10.1021/Cr010180A  0.33
2002 Watanabe S, Córdova A, Tanaka F, Barbas CF. One-pot asymmetric synthesis of beta-cyanohydroxymethyl alpha-amino acid derivatives: formation of three contiguous stereogenic centers. Organic Letters. 4: 4519-22. PMID 12465927 DOI: 10.1021/Ol027048X  0.478
2002 Tanaka F, Barbas CF. Reactive immunization: a unique approach to catalytic antibodies. Journal of Immunological Methods. 269: 67-79. PMID 12379353 DOI: 10.1016/S0022-1759(02)00225-9  0.381
2002 Tanaka F, Barbas CF. A modular assembly strategy for improving the substrate specificity of small catalytic peptides. Journal of the American Chemical Society. 124: 3510-1. PMID 11929232 DOI: 10.1021/Ja0171815  0.334
2002 Córdova A, Watanabe S, Tanaka F, Notz W, Barbas CF. A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives. Journal of the American Chemical Society. 124: 1866-7. PMID 11866595 DOI: 10.1021/Ja017833P  0.446
2002 Thayumanavan R, Dhevalapally B, Sakthivel K, Tanaka F, Barbas CF. Amine-catalyzed direct Diels-Alder reactions of α,β-unsaturated ketones with nitro olefins Tetrahedron Letters. 43: 3817-3820. DOI: 10.1016/S0040-4039(02)00686-X  0.533
2001 Tanaka F, Kerwin L, Kubitz D, Lerner RA, Barbas CF. Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions. Bioorganic & Medicinal Chemistry Letters. 11: 2983-6. PMID 11677141 DOI: 10.1016/S0960-894X(01)00605-9  0.647
2001 Tanaka F, Barbas CF. Phage display selection of peptides possessing aldolase activity Chemical Communications. 769-770. DOI: 10.1039/B100479B  0.374
2000 Karlstrom A, Zhong G, Rader C, Larsen NA, Heine A, Fuller R, List B, Tanaka F, Wilson IA, Barbas CF, Lerner RA. Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task. Proceedings of the National Academy of Sciences of the United States of America. 97: 3878-83. PMID 10760259 DOI: 10.1073/Pnas.97.8.3878  0.717
2000 Tanaka F, Lerner RA, Barbas CF. Reconstructing aldolase antibodies to alter their substrate specificity and turnover Journal of the American Chemical Society. 122: 4835-4836. DOI: 10.1021/Ja0005441  0.494
1999 Tanaka F, Lerner RA, Barbas CF. Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy Chemical Communications. 1383-1384. DOI: 10.1039/A902337B  0.573
1999 Tanaka F, Almer H, Lerner RA, Barbas CF. Catalytic single-chain antibodies possessing β-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor Tetrahedron Letters. 40: 8063-8066. DOI: 10.1016/S0040-4039(99)01695-0  0.515
1998 Tanaka F, Oda M, Fujii I. Pyridoxal-mediated abzyme system for aldol and retro-aldol reactions Tetrahedron Letters. 39: 5057-5060. DOI: 10.1016/S0040-4039(98)00952-6  0.53
1996 Fujii I, Tanaka F, Miyashita H, Tanimura R, Kinoshita K. Transition state analysis within a panel of catalytic antibodies generated against a phosphonate transition state analog Phosphorus, Sulfur and Silicon and Related Elements. 109: 253-256. DOI: 10.1080/10426509608046246  0.314
1996 Tanaka F, Kinoshita K, Tanimura R, Fujii I. Relaxing substrate specificity in antibody-catalyzed reactions: Enantioselective hydrolysis of N-Cbz-amino acid esters Journal of the American Chemical Society. 118: 2332-2339. DOI: 10.1021/Ja952220W  0.423
1995 Tanaka F, Node M, Tanaka K, Mizuchi M, Hosoi S, Nakayama M, Taga T, Fuji K. 1,1′-binaphthalene-2,2′-diol as a chiral auxiliary. Diastereoselective alkylation of binaphthyl esters, complex-induced proximity effects in enolate formation, and one-step synthesis of an optically active β-substituted ketone Journal of the American Chemical Society. 117: 12159-12171. DOI: 10.1021/Ja00154A016  0.548
1995 Fujii I, Tanaka F, Miyashita H, Tanimura R, Kinoshita K. Correlation between antigen-combining-site structures and functions within a panel of catalytic antibodies generated against a single transition state analog Journal of the American Chemical Society. 117: 6199-6209. DOI: 10.1021/Ja00128A006  0.308
1995 Okahata Y, Yamaguchi M, Tanaka F, Fujii I. A lipid-coated catalytic antibody in water-miscible organic solvents Tetrahedron. 51: 7673-7680. DOI: 10.1016/0040-4020(95)00407-Y  0.327
1994 Miyashita H, Hara T, Tamimura R, Tanaka F, Kikuchi M, Fujii I. A common ancestry for multiple catalytic antibodies generated against a single transition-state analog Proceedings of the National Academy of Sciences of the United States of America. 91: 10757. PMID 7938025 DOI: 10.1073/Pnas.91.22.10757A  0.359
1992 Tanaka F, Fuji K. Stereochemistry of the enolate from methyl phenylacetate Tetrahedron Letters. 33: 7885-7888. DOI: 10.1016/S0040-4039(00)74769-1  0.497
1991 Fujia K, Tanaka F, Node M. Binaphthol as a chiral auxilliary: diastereoselective alkylation of binaphthyl esters of α,β-unsaturated carboxylic acids Tetrahedron Letters. 32: 7281-7282. DOI: 10.1016/0040-4039(91)80498-U  0.302
1990 Fuji K, Node M, Tanaka F. Complex-induced proximity effects in enolate formation. Highly diastereoselective α-methylation of binaphthyl esters of arylacetic acids Tetrahedron Letters. 31: 6553-6556. DOI: 10.1016/S0040-4039(00)97115-6  0.521
1989 Fuji K, Node M, Tanaka F, Hosoi S. Binaphthol as a chiral auxiliary. Asymmetrical alkylation of arylacetic acid Tetrahedron Letters. 30: 2825-2828. DOI: 10.1016/S0040-4039(00)99135-4  0.557
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