| Year |
Citation |
Score |
| 2019 |
Polverino F, Lu B, Quintero JR, Vargas SO, Patel AS, Owen CA, Gerard NP, Gerard C, Cernadas M. CFTR regulates B cell activation and lymphoid follicle development. Respiratory Research. 20: 133. PMID 31262295 DOI: 10.1186/S12931-019-1103-1 |
0.308 |
|
| 2019 |
Karnezis T, Farnsworth R, Harris NC, Williams SP, Caesar C, Byrne DJ, Herle P, Macheda ML, Shayan R, Zhang YF, Yazar S, Takouridis SJ, Gerard C, Fox S, Achen MG, et al. CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS. Cancer Research. PMID 30709930 DOI: 10.1158/0008-5472.Can-18-1858 |
0.344 |
|
| 2018 |
Roux D, Schaefers M, Clark BS, Weatherholt M, Renaud D, Scott D, LiPuma JJ, Priebe G, Gerard C, Yoder-Himes DR. A putative lateral flagella of the cystic fibrosis pathogen Burkholderia dolosa regulates swimming motility and host cytokine production. Plos One. 13: e0189810. PMID 29346379 DOI: 10.1371/Journal.Pone.0189810 |
0.314 |
|
| 2018 |
Muenstermann M, Herrmann J, Strobel L, Woodruff T, Klos A, Wetsel R, Gerard C, Köhl J, Johswich KO. The distinct roles of the anaphylatoxin receptors C5aR1, C5aR2 and C3aR during experimental invasive meningococcal disease Molecular Immunology. 102: 168-169. DOI: 10.1016/J.Molimm.2018.06.109 |
0.349 |
|
| 2017 |
Roux D, Weatherholt M, Clark B, Gadjeva M, Renaud D, Scott D, Skurnik D, Priebe GP, Pier G, Gerard C, Yoder-Himes DR. HOST IMMUNE RECOGNITION OF THE EPIDEMIC CYSTIC FIBROSIS PATHOGEN BURKHOLDERIA DOLOSA. Infection and Immunity. PMID 28348057 DOI: 10.1128/Iai.00765-16 |
0.316 |
|
| 2016 |
Wang R, Lu B, Gerard C, Gerard NP. C5L2, the Second C5a Anaphylatoxin Receptor Suppresses Lipopolysaccharide-induced Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 27285858 DOI: 10.1165/Rcmb.2016-0067Oc |
0.404 |
|
| 2015 |
Gerard NP, Gerard C. Cloning of the Human C5a Anaphylatoxin Receptor, and More. Frontiers in Immunology. 6: 445. PMID 26388870 DOI: 10.3389/Fimmu.2015.00445 |
0.442 |
|
| 2015 |
Spaan AN, Schiepers A, de Haas CJ, van Hooijdonk DD, Badiou C, Contamin H, Vandenesch F, Lina G, Gerard NP, Gerard C, van Kessel KP, Henry T, van Strijp JA. Differential Interaction of the Staphylococcal Toxins Panton-Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors. Journal of Immunology (Baltimore, Md. : 1950). PMID 26091719 DOI: 10.4049/Jimmunol.1500604 |
0.396 |
|
| 2015 |
Han X, Feng Y, Chen X, Gerard C, Boisvert WA. Characterization of G protein coupling mediated by the conserved D134(3.49) of DRY motif, M241(6.34), and F251(6.44) residues on human CXCR1. Febs Open Bio. 5: 182-90. PMID 25834784 DOI: 10.1016/J.Fob.2015.03.001 |
0.365 |
|
| 2014 |
Casey A, Dirks F, Liang OD, Harrach H, Schuette-Nuetgen K, Leeman K, Kim CF, Gerard C, Subramaniam M. Bone marrow-derived multipotent stromal cells attenuate inflammation in obliterative airway disease in mouse tracheal allografts. Stem Cells International. 2014: 468927. PMID 25295064 DOI: 10.1155/2014/468927 |
0.326 |
|
| 2014 |
Saxena A, Bujak M, Frunza O, Dobaczewski M, Gonzalez-Quesada C, Lu B, Gerard C, Frangogiannis NG. CXCR3-independent actions of the CXC chemokine CXCL10 in the infarcted myocardium and in isolated cardiac fibroblasts are mediated through proteoglycans. Cardiovascular Research. 103: 217-27. PMID 24891401 DOI: 10.1093/Cvr/Cvu138 |
0.338 |
|
| 2014 |
Kim H, Erdman LK, Lu Z, Serghides L, Zhong K, Dhabangi A, Musoke C, Gerard C, Cserti-Gazdewich C, Liles WC, Kain KC. Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria. Infection and Immunity. 82: 371-9. PMID 24191300 DOI: 10.1128/Iai.01246-13 |
0.379 |
|
| 2014 |
Xiao H, Dairaghi DJ, Powers JP, Ertl LS, Baumgart T, Wang Y, Seitz LC, Penfold ME, Gan L, Hu P, Lu B, Gerard NP, Gerard C, Schall TJ, Jaen JC, et al. C5a receptor (CD88) blockade protects against MPO-ANCA GN. Journal of the American Society of Nephrology : Jasn. 25: 225-31. PMID 24179165 DOI: 10.1681/Asn.2013020143 |
0.359 |
|
| 2014 |
Rajagopal S, Bassoni D, Campbell J, Gerard N, Gerard C, Wehrman T. Understanding the mechanism of biased agonism at chemokine receptors (1066.17) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1066.17 |
0.377 |
|
| 2013 |
Rajagopal S, Bassoni DL, Campbell JJ, Gerard NP, Gerard C, Wehrman TS. Biased agonism as a mechanism for differential signaling by chemokine receptors. The Journal of Biological Chemistry. 288: 35039-48. PMID 24145037 DOI: 10.1074/Jbc.M113.479113 |
0.373 |
|
| 2013 |
Wang R, Lu B, Gerard C, Gerard NP. Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis. Journal of Immunology (Baltimore, Md. : 1950). 191: 4001-9. PMID 24043888 DOI: 10.4049/Jimmunol.1301626 |
0.432 |
|
| 2013 |
Kumar L, Lu B, Gerard C, Geha RS. C3a receptor promotes viral containment in mice inoculated with vaccinia virus at sites of allergic skin inflammation. The Journal of Allergy and Clinical Immunology. 132: 746-748.e3. PMID 23684067 DOI: 10.1016/J.Jaci.2013.03.041 |
0.385 |
|
| 2013 |
Agnello D, Denimal D, Lavaux A, Blondeau-Germe L, Lu B, Gerard NP, Gerard C, Pothier P. Intrarectal immunization and IgA antibody-secreting cell homing to the small intestine. Journal of Immunology (Baltimore, Md. : 1950). 190: 4836-47. PMID 23547118 DOI: 10.4049/Jimmunol.1202979 |
0.363 |
|
| 2013 |
Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ. Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice. The Journal of Allergy and Clinical Immunology. 131: 541-8.e1-9. PMID 22728083 DOI: 10.1016/J.Jaci.2012.05.009 |
0.383 |
|
| 2011 |
Bera MM, Lu B, Martin TR, Cui S, Rhein LM, Gerard C, Gerard NP. Th17 cytokines are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and tachykinins. Journal of Immunology (Baltimore, Md. : 1950). 187: 4245-55. PMID 21918196 DOI: 10.4049/Jimmunol.1101789 |
0.424 |
|
| 2011 |
Dimond P, Carlson K, Bouvier M, Gerard C, Xu L, Covic L, Agarwal A, Ernst OP, Janz JM, Schwartz TW, Gardella TJ, Milligan G, Kuliopulos A, Sakmar TP, Hunt SW. G protein-coupled receptor modulation with pepducins: moving closer to the clinic. Annals of the New York Academy of Sciences. 1226: 34-49. PMID 21615752 DOI: 10.1111/J.1749-6632.2011.06039.X |
0.347 |
|
| 2011 |
Oberbarnscheidt MH, Walch JM, Li Q, Williams AL, Walters JT, Hoffman RA, Demetris AJ, Gerard C, Camirand G, Lakkis FG. Memory T cells migrate to and reject vascularized cardiac allografts independent of the chemokine receptor CXCR3. Transplantation. 91: 827-32. PMID 21285915 DOI: 10.1097/Tp.0B013E31820F0856 |
0.309 |
|
| 2011 |
Struyf S, Salogni L, Burdick MD, Vandercappellen J, Gouwy M, Noppen S, Proost P, Opdenakker G, Parmentier M, Gerard C, Sozzani S, Strieter RM, Van Damme J. Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3. Blood. 117: 480-8. PMID 20980681 DOI: 10.1182/Blood-2009-11-253591 |
0.376 |
|
| 2011 |
Voort Rvd, Brandao C, Volman TJ, Verweij V, Gisbergen Kv, Lu B, Gerard C, Nolte MA, Dolstra H. CXCR3 Is Required for the Efficient Recruitment of Bone Marrow-Resident Memory T Cells to Inflamed Tissues, Blood. 118: 3242-3242. DOI: 10.1182/Blood.V118.21.3242.3242 |
0.341 |
|
| 2011 |
Banda N, Hyatt S, Glogowska M, Takahashi K, Merkel T, Stahl G, Lu B, Gerard C, Wetsel R, Arend W, Holers V. Independent roles for complement C3a and C5a receptors and the membrane attack complex in the pathogenesis of collagen antibody-induced arthritis in mice: Potential therapeutic implications Molecular Immunology. 48: 1670. DOI: 10.1016/J.Molimm.2011.06.234 |
0.371 |
|
| 2010 |
Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, König P, Gerard NP, Gerard C, Wills-Karp M, Köhl J. A critical role for C5L2 in the pathogenesis of experimental allergic asthma. Journal of Immunology (Baltimore, Md. : 1950). 185: 6741-52. PMID 20974988 DOI: 10.4049/Jimmunol.1000892 |
0.401 |
|
| 2010 |
Nigrovic PA, Malbec O, Lu B, Markiewski MM, Kepley C, Gerard N, Gerard C, Daëron M, Lee DM. C5a receptor enables participation of mast cells in immune complex arthritis independently of Fcγ receptor modulation. Arthritis and Rheumatism. 62: 3322-33. PMID 20662064 DOI: 10.1002/Art.27659 |
0.445 |
|
| 2010 |
Bamberg CE, Mackay CR, Lee H, Zahra D, Jackson J, Lim YS, Whitfeld PL, Craig S, Corsini E, Lu B, Gerard C, Gerard NP. The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. The Journal of Biological Chemistry. 285: 7633-44. PMID 20044484 DOI: 10.1074/Jbc.M109.092106 |
0.4 |
|
| 2010 |
Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proceedings of the National Academy of Sciences of the United States of America. 107: 628-32. PMID 20018651 DOI: 10.1073/Pnas.0912852107 |
0.337 |
|
| 2010 |
Weaver DJ, Reis ES, Pandey MK, Köhl G, Harris N, Gerard C, Köhl J. C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells. European Journal of Immunology. 40: 710-21. PMID 20017191 DOI: 10.1002/Eji.200939333 |
0.383 |
|
| 2010 |
Pandey MK, Figge J, Karsten CM, Madaio M, Gerard C, Köhl J. A novel role for C5a in B-cell regulation driving the pathology in immune complex nephritis Molecular Immunology. 47: 2232-2232. DOI: 10.1016/J.Molimm.2010.05.108 |
0.324 |
|
| 2009 |
Nakanishi Y, Lu B, Gerard C, Iwasaki A. CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help. Nature. 462: 510-3. PMID 19898495 DOI: 10.1038/Nature08511 |
0.305 |
|
| 2009 |
Dib M, Zsengeller Z, Mitsialis A, Lu B, Craig S, Gerard C, Gerard NP. A paradoxical protective role for the proinflammatory peptide substance P receptor (NK1R) in acute hyperoxic lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L687-97. PMID 19633070 DOI: 10.1152/Ajplung.90509.2008 |
0.393 |
|
| 2009 |
Ye RD, Boulay F, Wang JM, Dahlgren C, Gerard C, Parmentier M, Serhan CN, Murphy PM. International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family. Pharmacological Reviews. 61: 119-61. PMID 19498085 DOI: 10.1124/Pr.109.001578 |
0.377 |
|
| 2009 |
Markiewski MM, DeAngelis RA, Strey CW, Foukas PG, Gerard C, Gerard N, Wetsel RA, Lambris JD. The regulation of liver cell survival by complement. Journal of Immunology (Baltimore, Md. : 1950). 182: 5412-8. PMID 19380788 DOI: 10.4049/Jimmunol.0804179 |
0.351 |
|
| 2009 |
Dempsey EC, Wick MJ, Karoor V, Barr EJ, Tallman DW, Wehling CA, Walchak SJ, Laudi S, Le M, Oka M, Majka S, Cool CD, Fagan KA, Klemm DJ, Hersh LB, ... ... Gerard C, et al. Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. The American Journal of Pathology. 174: 782-96. PMID 19234135 DOI: 10.2353/Ajpath.2009.080345 |
0.307 |
|
| 2008 |
Morteau O, Gerard C, Lu B, Ghiran S, Rits M, Fujiwara Y, Law Y, Distelhorst K, Nielsen EM, Hill ED, Kwan R, Lazarus NH, Butcher EC, Wilson E. An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation. Journal of Immunology (Baltimore, Md. : 1950). 181: 6309-15. PMID 18941222 DOI: 10.4049/Jimmunol.181.9.6309 |
0.424 |
|
| 2008 |
Riemer C, Schultz J, Burwinkel M, Schwarz A, Mok SW, Gültner S, Bamme T, Norley S, van Landeghem F, Lu B, Gerard C, Baier M. Accelerated prion replication in, but prolonged survival times of, prion-infected CXCR3-/- mice. Journal of Virology. 82: 12464-71. PMID 18842729 DOI: 10.1128/Jvi.01371-08 |
0.392 |
|
| 2008 |
Markiewski MM, DeAngelis RA, Benencia F, Ricklin-Lichtsteiner SK, Koutoulaki A, Gerard C, Coukos G, Lambris JD. Modulation of the antitumor immune response by complement. Nature Immunology. 9: 1225-35. PMID 18820683 DOI: 10.1038/Ni.1655 |
0.335 |
|
| 2008 |
Uppaluri R, Sheehan KC, Wang L, Bui JD, Brotman JJ, Lu B, Gerard C, Hancock WW, Schreiber RD. Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody. Transplantation. 86: 137-47. PMID 18622291 DOI: 10.1097/Tp.0B013E31817B8E4B |
0.352 |
|
| 2008 |
Kohlmeier JE, Miller SC, Smith J, Lu B, Gerard C, Cookenham T, Roberts AD, Woodland DL. The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections. Immunity. 29: 101-13. PMID 18617426 DOI: 10.1016/J.Immuni.2008.05.011 |
0.361 |
|
| 2008 |
Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A. Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology. 135: 194-204.e3. PMID 18485912 DOI: 10.1053/J.Gastro.2008.03.023 |
0.321 |
|
| 2008 |
Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Köhl J, Gerard C, Sarma JV, Ward PA. Functional roles for C5a receptors in sepsis. Nature Medicine. 14: 551-7. PMID 18454156 DOI: 10.1038/Nm1753 |
0.42 |
|
| 2008 |
Rhein LM, Perkins M, Gerard NP, Gerard C. FcgammaRIII is protective against Pseudomonas aeruginosa pneumonia. American Journal of Respiratory Cell and Molecular Biology. 38: 401-6. PMID 17975174 DOI: 10.1165/Rcmb.2007-0309Oc |
0.431 |
|
| 2007 |
Müller M, Carter SL, Hofer MJ, Manders P, Getts DR, Getts MT, Dreykluft A, Lu B, Gerard C, King NJ, Campbell IL. CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 179: 2774-86. PMID 17709491 DOI: 10.4049/Jimmunol.179.5.2774 |
0.415 |
|
| 2007 |
Nakaya I, Wada T, Furuichi K, Sakai N, Kitagawa K, Yokoyama H, Ishida Y, Kondo T, Sugaya T, Kawachi H, Shimizu F, Narumi S, Haino M, Gerard C, Matsushima K, et al. Blockade of IP-10/CXCR3 promotes progressive renal fibrosis. Nephron. Experimental Nephrology. 107: e12-21. PMID 17671396 DOI: 10.1159/000106505 |
0.326 |
|
| 2007 |
Miao Z, Premack BA, Wei Z, Wang Y, Gerard C, Showell H, Howard M, Schall TJ, Berahovich R. Proinflammatory proteases liberate a discrete high-affinity functional FPRL1 (CCR12) ligand from CCL23. Journal of Immunology (Baltimore, Md. : 1950). 178: 7395-404. PMID 17513790 DOI: 10.4049/Jimmunol.178.11.7395 |
0.403 |
|
| 2007 |
Barbi J, Oghumu S, Rosas LE, Carlson T, Lu B, Gerard C, Lezama-Davila CM, Satoskar AR. Lack of CXCR3 delays the development of hepatic inflammation but does not impair resistance to Leishmania donovani. The Journal of Infectious Diseases. 195: 1713-7. PMID 17471442 DOI: 10.1086/516787 |
0.38 |
|
| 2007 |
Chakravarty SD, Xu J, Lu B, Gerard C, Flynn J, Chan J. The chemokine receptor CXCR3 attenuates the control of chronic Mycobacterium tuberculosis infection in BALB/c mice Journal of Immunology. 178: 1723-1735. PMID 17237422 DOI: 10.4049/Jimmunol.178.3.1723 |
0.412 |
|
| 2007 |
Melendi GA, Hoffman SJ, Karron RA, Irusta PM, Laham FR, Humbles A, Schofield B, Pan CH, Rabold R, Thumar B, Thumar A, Gerard NP, Mitzner W, Barnum SR, Gerard C, et al. C5 modulates airway hyperreactivity and pulmonary eosinophilia during enhanced respiratory syncytial virus disease by decreasing C3a receptor expression. Journal of Virology. 81: 991-9. PMID 17079327 DOI: 10.1128/Jvi.01783-06 |
0.381 |
|
| 2006 |
Hsieh MF, Lai SL, Chen JP, Sung JM, Lin YL, Wu-Hsieh BA, Gerard C, Luster A, Liao F. Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. Journal of Immunology (Baltimore, Md. : 1950). 177: 1855-63. PMID 16849497 DOI: 10.4049/Jimmunol.177.3.1855 |
0.379 |
|
| 2006 |
Kristensen NN, Gad M, Thomsen AR, Lu B, Gerard C, Claesson MH. CXC chemokine receptor 3 expression increases the disease-inducing potential of CD4+ CD25- T cells in adoptive transfer colitis. Inflammatory Bowel Diseases. 12: 374-81. PMID 16670526 DOI: 10.1097/01.Mib.0000217337.15442.E1 |
0.406 |
|
| 2006 |
Wald O, Weiss ID, Wald H, Shoham H, Bar-Shavit Y, Beider K, Galun E, Weiss L, Flaishon L, Shachar I, Nagler A, Lu B, Gerard C, Gao JL, Mishani E, et al. IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. Journal of Immunology (Baltimore, Md. : 1950). 176: 4716-29. PMID 16585565 DOI: 10.4049/Jimmunol.176.8.4716 |
0.338 |
|
| 2006 |
Liu L, Huang D, Matsui M, He TT, Hu T, DeMartino J, Lu B, Gerard C, Ransohoff RM. Severe disease, unaltered leukocyte migration, and reduced IFN-γ production in CXCR3-/- mice with experimental autoimmune encephalomyelitis Journal of Immunology. 176: 4399-4409. PMID 16547278 DOI: 10.4049/Jimmunol.176.7.4399 |
0.408 |
|
| 2006 |
Köhl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M. A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. The Journal of Clinical Investigation. 116: 783-96. PMID 16511606 DOI: 10.1172/Jci26582 |
0.41 |
|
| 2006 |
Rahpeymai Y, Hietala MA, Wilhelmsson U, Fotheringham A, Davies I, Nilsson AK, Zwirner J, Wetsel RA, Gerard C, Pekny M, Pekna M. Complement: a novel factor in basal and ischemia-induced neurogenesis. The Embo Journal. 25: 1364-74. PMID 16498410 DOI: 10.1038/Sj.Emboj.7601004 |
0.395 |
|
| 2006 |
Miller AL, Gerard C, Schaller M, Gruber AD, Humbles AA, Lukacs NW. Deletion of CCR1 attenuates pathophysiologic responses during respiratory syncytial virus infection. Journal of Immunology (Baltimore, Md. : 1950). 176: 2562-7. PMID 16456018 DOI: 10.4049/Jimmunol.176.4.2562 |
0.399 |
|
| 2006 |
Pan J, Burdick MD, Belperio JA, Xue YY, Gerard C, Sharma S, Dubinett SM, Strieter RM. CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis. Journal of Immunology (Baltimore, Md. : 1950). 176: 1456-64. PMID 16424173 DOI: 10.4049/Jimmunol.176.3.1456 |
0.316 |
|
| 2005 |
Gerard NP, Lu B, Liu P, Craig S, Fujiwara Y, Okinaga S, Gerard C. An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2. The Journal of Biological Chemistry. 280: 39677-80. PMID 16204243 DOI: 10.1074/Jbc.C500287200 |
0.417 |
|
| 2005 |
Veillard NR, Steffens S, Pelli G, Lu B, Kwak BR, Gerard C, Charo IF, Mach F. Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo. Circulation. 112: 870-8. PMID 16061736 DOI: 10.1161/Circulationaha.104.520718 |
0.427 |
|
| 2005 |
Yoneyama H, Matsuno K, Toda E, Nishiwaki T, Matsuo N, Nakano A, Narumi S, Lu B, Gerard C, Ishikawa S, Matsushima K. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. The Journal of Experimental Medicine. 202: 425-35. PMID 16061729 DOI: 10.1084/Jem.20041961 |
0.362 |
|
| 2005 |
De Lemos C, Christensen JE, Nansen A, Moos T, Lu B, Gerard C, Christensen JP, Thomsen AR. Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice Journal of Immunology. 175: 1767-1775. PMID 16034118 DOI: 10.4049/Jimmunol.175.3.1767 |
0.429 |
|
| 2005 |
Lee BJ, Giannoni F, Lyon A, Yada S, Lu B, Gerard C, Sarawar SR. Role of CXCR3 in the immune response to murine gammaherpesvirus 68. Journal of Virology. 79: 9351-5. PMID 15994833 DOI: 10.1128/Jvi.79.14.9351-9355.2005 |
0.42 |
|
| 2005 |
Honczarenko M, Lu B, Nicholson-Weller A, Gerard NP, Silberstein LE, Gerard C. C5L2 receptor is not involved in C3a / C3a-desArg-mediated enhancement of bone marrow hematopoietic cell migration to CXCL12 Leukemia. 19: 1682-1683. PMID 15990859 DOI: 10.1038/Sj.Leu.2403862 |
0.345 |
|
| 2005 |
Hawlisch H, Belkaid Y, Baelder R, Hildeman D, Gerard C, Köhl J. C5a negatively regulates toll-like receptor 4-induced immune responses. Immunity. 22: 415-26. PMID 15845447 DOI: 10.1016/J.Immuni.2005.02.006 |
0.383 |
|
| 2005 |
Yamagami S, Hamrah P, Miyamoto K, Miyazaki D, Dekaris I, Dawson T, Lu B, Gerard C, Dana MR. CCR5 chemokine receptor mediates recruitment of MHC class II-positive Langerhans cells in the mouse corneal epithelium. Investigative Ophthalmology & Visual Science. 46: 1201-7. PMID 15790880 DOI: 10.1167/Iovs.04-0658 |
0.362 |
|
| 2005 |
Gerard C. Inflammatory chemokines: tuned in, turned on, dropped out. Nature Immunology. 6: 366-8. PMID 15785765 DOI: 10.1038/Ni0405-366 |
0.328 |
|
| 2005 |
Waeckel L, Mallat Z, Potteaux S, Combadière C, Clergue M, Duriez M, Bao L, Gerard C, Rollins BJ, Tedgui A, Levy BI, Silvestre JS. Impairment in postischemic neovascularization in mice lacking the CXC chemokine receptor 3. Circulation Research. 96: 576-82. PMID 15718500 DOI: 10.1161/01.Res.0000159389.55544.20 |
0.413 |
|
| 2005 |
Rosas LE, Barbi J, Lu B, Fujiwara Y, Gerard C, Sanders VM, Satoskar AR. CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection. European Journal of Immunology. 35: 515-23. PMID 15668916 DOI: 10.1002/Eji.200425422 |
0.387 |
|
| 2005 |
Widney DP, Hu Y, Foreman-Wykert AK, Bui KC, Nguyen TT, Lu B, Gerard C, Miller JF, Smith JB. CXCR3 and its ligands participate in the host response to Bordetella bronchiseptica infection of the mouse respiratory tract but are not required for clearance of bacteria from the lung. Infection and Immunity. 73: 485-93. PMID 15618188 DOI: 10.1128/Iai.73.1.485-493.2005 |
0.439 |
|
| 2004 |
Martín-Fontecha A, Thomsen LL, Brett S, Gerard C, Lipp M, Lanzavecchia A, Sallusto F. Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nature Immunology. 5: 1260-5. PMID 15531883 DOI: 10.1038/Ni1138 |
0.313 |
|
| 2004 |
Chiu BC, Freeman CM, Stolberg VR, Hu JS, Zeibecoglou K, Lu B, Gerard C, Charo IF, Lira SA, Chensue SW. Impaired lung dendritic cell activation in CCR2 knockout mice. The American Journal of Pathology. 165: 1199-209. PMID 15466386 DOI: 10.1016/S0002-9440(10)63380-9 |
0.411 |
|
| 2004 |
Rappert A, Bechmann I, Pivneva T, Mahlo J, Biber K, Nolte C, Kovac AD, Gerard C, Boddeke HW, Nitsch R, Kettenmann H. CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8500-9. PMID 15456824 DOI: 10.1523/Jneurosci.2451-04.2004 |
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Humbles AA, Lloyd CM, McMillan SJ, Friend DS, Xanthou G, McKenna EE, Ghiran S, Gerard NP, Yu C, Orkin SH, Gerard C. A critical role for eosinophils in allergic airways remodeling. Science (New York, N.Y.). 305: 1776-9. PMID 15375268 DOI: 10.1126/Science.1100283 |
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Godau J, Heller T, Hawlisch H, Trappe M, Howells E, Best J, Zwirner J, Verbeek JS, Hogarth PM, Gerard C, Van Rooijen N, Klos A, Gessner JE, Köhl J. C5a initiates the inflammatory cascade in immune complex peritonitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 3437-45. PMID 15322209 DOI: 10.4049/Jimmunol.173.5.3437 |
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Kawamoto S, Yalcindag A, Laouini D, Brodeur S, Bryce P, Lu B, Humbles AA, Oettgen H, Gerard C, Geha RS. The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen. The Journal of Clinical Investigation. 114: 399-407. PMID 15286806 DOI: 10.1172/Jci19082 |
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Jiang D, Liang J, Hodge J, Lu B, Zhu Z, Yu S, Fan J, Gao Y, Yin Z, Homer R, Gerard C, Noble PW. Regulation of pulmonary fibrosis by chemokine receptor CXCR3. The Journal of Clinical Investigation. 114: 291-9. PMID 15254596 DOI: 10.1172/Jci16861 |
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Wareing MD, Lyon AB, Lu B, Gerard C, Sarawar SR. Chemokine expression during the development and resolution of a pulmonary leukocyte response to influenza A virus infection in mice. Journal of Leukocyte Biology. 76: 886-95. PMID 15240757 DOI: 10.1189/Jlb.1203644 |
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Yoneyama H, Matsuno K, Zhang Y, Nishiwaki T, Kitabatake M, Ueha S, Narumi S, Morikawa S, Ezaki T, Lu B, Gerard C, Ishikawa S, Matsushima K. Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. International Immunology. 16: 915-28. PMID 15159375 DOI: 10.1093/Intimm/Dxh093 |
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Christensen JE, Nansen A, Moos T, Lu B, Gerard C, Christensen JP, Thomsen AR. Efficient T-cell surveillance of the CNS requires expression of the CXC chemokine receptor 3 Journal of Neuroscience. 24: 4849-4858. PMID 15152045 DOI: 10.1523/Jneurosci.0123-04.2004 |
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Akahira-Azuma M, Szczepanik M, Tsuji RF, Campos RA, Itakura A, Mobini N, McNiff J, Kawikova I, Lu B, Gerard C, Pober JS, Askenase PW. Early delayed-type hypersensitivity eosinophil infiltrates depend on T helper 2 cytokines and interferon-gamma via CXCR3 chemokines. Immunology. 111: 306-17. PMID 15009431 DOI: 10.1111/J.0019-2805.2004.01818.X |
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Ma B, Zhu Z, Homer RJ, Gerard C, Strieter R, Elias JA. The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling. Journal of Immunology (Baltimore, Md. : 1950). 172: 1872-81. PMID 14734772 DOI: 10.4049/Jimmunol.172.3.1872 |
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Duffner U, Lu B, Hildebrandt GC, Teshima T, Williams DL, Reddy P, Ordemann R, Clouthier SG, Lowler K, Liu C, Gerard C, Cooke KR, Ferrara JL. Role of CXCR3-induced donor T-cell migration in acute GVHD. Experimental Hematology. 31: 897-902. PMID 14550805 DOI: 10.1016/S0301-472X(03)00198-X |
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Seiler P, Aichele P, Bandermann S, Hauser AE, Lu B, Gerard NP, Gerard C, Ehlers S, Mollenkopf HJ, Kaufmann SE. Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3‐signaling chemokines European Journal of Immunology. 33: 2676-2686. PMID 14515251 DOI: 10.1002/Eji.200323956 |
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Barbara G, De Giorgio R, Stanghellini V, Corinaldesi R, Cremon C, Gerard N, Gerard C, Grady EF, Bunnett NW, Blennerhassett PA, Collins SM. Neutral endopeptidase (EC 3.4.24.11) downregulates the onset of intestinal inflammation in the nematode infected mouse. Gut. 52: 1457-64. PMID 12970139 DOI: 10.1136/Gut.52.10.1457 |
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Baker MS, Chen X, Rotramel AR, Nelson JJ, Lu B, Gerard C, Kanwar Y, Kaufman DB. Genetic deletion of chemokine receptor CXCR3 or antibody blockade of its ligand IP-10 modulates posttransplantation graft-site lymphocytic infiltrates and prolongs functional graft survival in pancreatic islet allograft recipients. Surgery. 134: 126-33. PMID 12947308 DOI: 10.1067/Msy.2003.213 |
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Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, Gerard C. C5L2, a nonsignaling C5A binding protein. Biochemistry. 42: 9406-15. PMID 12899627 DOI: 10.1021/Bi034489V |
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Gao J, Choe H, Bota D, Wright PL, Gerard C, Gerard NP. Sulfation of tyrosine 174 in the human C3a receptor is essential for binding of C3a anaphylatoxin. The Journal of Biological Chemistry. 278: 37902-8. PMID 12871936 DOI: 10.1074/Jbc.M306061200 |
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Rodriguez-Sosa M, Rosas LE, Terrazas LI, Lu B, Gerard C, Satoskar AR. CC chemokine receptor 1 enhances susceptibility to Leishmania major during early phase of infection. Immunology and Cell Biology. 81: 114-20. PMID 12631234 DOI: 10.1046/J.0818-9641.2002.01132.X |
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Gerard C. Complement C5a in the sepsis syndrome: Too much of a good thing? The New England Journal of Medicine. 348: 167-169. PMID 12519929 DOI: 10.1056/Nejmcibr022995 |
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Lee D, Brenner M, Gerard C, Benoist C, Mathis D, Watts G. Arthritis Research & Therapy. 5: 8. DOI: 10.1186/Ar809 |
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Grant EP, Picarella D, Burwell T, Delaney T, Croci A, Avitahl N, Humbles AA, Gutierrez-Ramos JC, Briskin M, Gerard C, Coyle AJ. Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis Journal of Experimental Medicine. 196: 1461-1471. PMID 12461081 DOI: 10.1084/Jem.20020205 |
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Frigerio S, Junt T, Lu B, Gerard C, Zumsteg U, Holländer GA, Piali L. β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis Nature Medicine. 8: 1414-1420. PMID 12415259 DOI: 10.1038/Nm1202-792 |
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Gerard NP, Gerard C. Complement in allergy and asthma. Current Opinion in Immunology. 14: 705-708. PMID 12413519 DOI: 10.1016/S0952-7915(02)00410-7 |
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Farzan M, Chung S, Li W, Vasilieva N, Wright PL, Schnitzler CE, Marchione RJ, Gerard C, Gerard NP, Sodroski J, Choe H. Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region. The Journal of Biological Chemistry. 277: 40397-402. PMID 12183462 DOI: 10.1074/Jbc.M206784200 |
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Luo Y, Berman MA, Zhai Q, Fischer FR, Abromson-Leeman SR, Zhang Y, Kuziel WA, Gerard C, Dorf ME. RANTES stimulates inflammatory cascades and receptor modulation in murine astrocytes. Glia. 39: 19-30. PMID 12112372 DOI: 10.1002/Glia.10079 |
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Gurish MF, Humbles A, Tao H, Finkelstein S, Boyce JA, Gerard C, Friend DS, Austen KF. CCR3 is required for tissue eosinophilia and larval cytotoxicity after infection with Trichinella spiralis. Journal of Immunology (Baltimore, Md. : 1950). 168: 5730-6. PMID 12023373 DOI: 10.4049/Jimmunol.168.11.5730 |
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Reiman R, Gerard C, Campbell IL, Barnum SR. Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis. European Journal of Immunology. 32: 1157-63. PMID 11932923 DOI: 10.1002/1521-4141(200204)32:4<1157::Aid-Immu1157>3.0.Co;2-M |
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Fischer HS, Zernig G, Hauser KF, Gerard C, Hersh LB, Saria A. Neutral endopeptidase knockout induces hyperalgesia in a model of visceral pain, an effect related to bradykinin and nitric oxide. Journal of Molecular Neuroscience : Mn. 18: 129-34. PMID 11931342 DOI: 10.1385/Jmn:18:1-2:129 |
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Rappert A, Biber K, Nolte C, Lipp M, Schubel A, Lu B, Gerard NP, Gerard C, Boddeke HW, Kettenmann H. Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia. Journal of Immunology (Baltimore, Md. : 1950). 168: 3221-6. PMID 11907075 DOI: 10.4049/Jimmunol.168.7.3221 |
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Ma W, Bryce PJ, Humbles AA, Laouini D, Yalcindag A, Alenius H, Friend DS, Oettgen HC, Gerard C, Geha RS. CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation. The Journal of Clinical Investigation. 109: 621-8. PMID 11877470 DOI: 10.1172/Jci14097 |
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Morteau O, Castagliuolo I, Mykoniatis A, Zacks J, Wlk M, Lu B, Pothoulakis C, Gerard NP, Gerard C. Genetic deficiency in the chemokine receptor CCR1 protects against acute Clostridium difficile toxin A enteritis in mice. Gastroenterology. 122: 725-33. PMID 11875005 DOI: 10.1053/Gast.2002.31873 |
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Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, et al. Arthritis critically dependent on innate immune system players. Immunity. 16: 157-68. PMID 11869678 DOI: 10.1016/S1074-7613(02)00275-3 |
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Humbles AA, Lu B, Friend DS, Okinaga S, Lora J, Al-Garawi A, Martin TR, Gerard NP, Gerard C. The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proceedings of the National Academy of Sciences of the United States of America. 99: 1479-84. PMID 11830666 DOI: 10.1073/Pnas.261462598 |
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Yalcindag A, Laouini D, Lu B, Bryce PJ, Humbles A, Oettgen HC, Gerard C, Geha RS. The complement receptor C3aR is an important regulator of Th cell polarization following epicutaneous sensitization with antigen Journal of Allergy and Clinical Immunology. 109: S279-S279. DOI: 10.1016/S0091-6749(02)81988-1 |
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Ma W, Bryce PJ, Humbles A, Laouini D, Yalcindag A, Alenius HT, Friend D, Oettgen HC, Gerard C, Geha RS. The CC chemokine receptor 3 is essential for skin eosinophilia and for airway hyper-responsiveness to inhaled antigen in a murine model of allergic skin inflammation Journal of Allergy and Clinical Immunology. 109: S256-S256. DOI: 10.1016/S0091-6749(02)81915-7 |
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Morteau O, Lu B, Gerard C, Gerard NP. Hemokinin 1 is a full agonist at the substance P receptor. Nature Immunology. 2: 1088-1088. PMID 11725292 DOI: 10.1038/Ni1201-1088 |
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Ottersbach K, Cook DN, Kuziel WA, Humbles A, Lu B, Gerard C, Proudfoot AEI, Graham GJ. Macrophage inflammatory protein-1α uses a novel receptor for primitive hemopoietic cell inhibition Blood. 98: 3476-3478. PMID 11719391 DOI: 10.1182/Blood.V98.12.3476 |
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Farzan M, Schnitzler CE, Vasilieva N, Leung D, Kuhn J, Gerard C, Gerard NP, Choe H. Sulfated tyrosines contribute to the formation of the C5a docking site of the human C5a anaphylatoxin receptor. The Journal of Experimental Medicine. 193: 1059-66. PMID 11342590 DOI: 10.1084/Jem.193.9.1059 |
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Bhatia M, Saluja AK, Singh VP, Frossard JL, Lee HS, Bhagat L, Gerard C, Steer ML. Complement factor C5a exerts an anti-inflammatory effect in acute pancreatitis and associated lung injury American Journal of Physiology-Gastrointestinal and Liver Physiology. 280. PMID 11292607 DOI: 10.1152/Ajpgi.2001.280.5.G974 |
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Gerard C, Gerard NP. Chemokines: back to the future? Nature Cell Biology. 3. PMID 11175764 DOI: 10.1038/35055166 |
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Slattery DM, Gerard N, Gerard C. Gene targeting of chemokines and their receptors. Springer Seminars in Immunopathology. 22: 417-32. PMID 11155444 DOI: 10.1007/S002810000055 |
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Shang X, Qiu B, Frait KA, Hu JS, Sonstein J, Curtis JL, Lu B, Gerard C, Chensue SW. Chemokine receptor 1 knockout abrogates natural killer cell recruitment and impairs type-1 cytokines in lymphoid tissue during pulmonary granuloma formation. The American Journal of Pathology. 157: 2055-63. PMID 11106578 DOI: 10.1016/S0002-9440(10)64844-4 |
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Fischer HS, Zernig G, Schuligoi R, Miczek KA, Hauser KF, Gerard C, Saria A. Alterations within the endogenous opioid system in mice with targeted deletion of the neutral endopeptidase ('enkephalinase') gene. Regulatory Peptides. 96: 53-8. PMID 11102652 DOI: 10.1016/S0167-0115(00)00200-7 |
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Hancock WW, Lu B, Gao W, Csizmadia V, Faia K, King JA, Smiley ST, Ling M, Gerard NP, Gerard C. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. The Journal of Experimental Medicine. 192: 1515-20. PMID 11085753 DOI: 10.1084/Jem.192.10.1515 |
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Humbles AA, Lu B, Nilsson CA, Lilly C, Israel E, Fujiwara Y, Gerard NP, Gerard C. A role for the C3a anaphylatoxin receptor in the effector phase of asthma Nature. 406: 998-1001. PMID 10984054 DOI: 10.1038/35023175 |
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Tsuji RF, Kawikova I, Ramabhadran R, Akahira-Azuma M, Taub D, Hugli TE, Gerard C, Askenase PW. Early Local Generation of C5a Initiates the Elicitation of Contact Sensitivity by Leading to Early T Cell Recruitment Journal of Immunology. 165: 1588-1598. PMID 10903768 DOI: 10.4049/Jimmunol.165.3.1588 |
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Blease K, Mehrad B, Standiford TJ, Lukacs NW, Kunkel SL, Chensue SW, Lu B, Gerard CJ, Hogaboam CM. Airway remodeling is absent in CCR1(-/-) mice during chronic fungal allergic airway disease Journal of Immunology. 165: 1564-1572. PMID 10903765 DOI: 10.4049/Jimmunol.165.3.1564 |
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Grady EF, Yoshimi SK, Maa J, Valeroso D, Vartanian RK, Rahim S, Kim EH, Gerard C, Gerard N, Bunnett NW, Kirkwood KS. Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice. British Journal of Pharmacology. 130: 505-12. PMID 10821777 DOI: 10.1038/Sj.Bjp.0703343 |
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Shi H, Humbles A, Gerard C, Jin Z, Weller PF. Lymph node trafficking and antigen presentation by endobronchial eosinophils Journal of Clinical Investigation. 105: 945-953. PMID 10749574 DOI: 10.1172/Jci8945 |
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Jarmin DI, Rits M, Bota D, Gerard NP, Graham GJ, Clark-Lewis I, Gerard C. Cutting edge: Identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine Journal of Immunology. 164: 3460-3464. PMID 10725696 DOI: 10.4049/Jimmunol.164.7.3460 |
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Saban R, Saban MR, Nguyen NB, Lu B, Gerard C, Gerard NP, Hammond TG. Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis. The American Journal of Pathology. 156: 775-80. PMID 10702392 DOI: 10.1016/S0002-9440(10)64944-9 |
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Topham PS, Csizmadia V, Soler D, Hines D, Gerard CJ, Salant DJ, Hancock WW. Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis. The Journal of Clinical Investigation. 104: 1549-57. PMID 10587518 DOI: 10.1172/JCI7707 |
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Lu B, Humbles A, Bota D, Gerard C, Moser B, Soler D, Luster AD, Gerard NP. Structure and function of the murine chemokine receptor CXCR3. European Journal of Immunology. 29: 3804-3812. PMID 10556837 DOI: 10.1002/(Sici)1521-4141(199911)29:11<3804::Aid-Immu3804>3.0.Co;2-9 |
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Sturiale S, Barbara G, Qiu B, Figini M, Geppetti P, Gerard N, Gerard C, Grady EF, Bunnett NW, Collins SM. Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. Proceedings of the National Academy of Sciences of the United States of America. 96: 11653-8. PMID 10500232 DOI: 10.1073/Pnas.96.20.11653 |
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Askenase PW, Kawikova I, Paliwal V, Akahira-Azuma M, Gerard C, Hugli T, Tsuji R. A new paradigm of T cell allergy: requirement for the B-1 cell subset. International Archives of Allergy and Immunology. 118: 145-149. PMID 10224363 DOI: 10.1159/000024052 |
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Farzan M, Mirzabekov T, Kolchinsky P, Wyatt R, Cayabyab M, Gerard NP, Gerard C, Sodroski J, Choe H. Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry. Cell. 96: 667-76. PMID 10089882 DOI: 10.1016/S0092-8674(00)80577-2 |
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Bozza M, Satoskar AR, Lin G, Lu B, Humbles AA, Gerard C, David JR. Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis. The Journal of Experimental Medicine. 189: 341-6. PMID 9892616 DOI: 10.1084/Jem.189.2.341 |
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Gerard C. Bacterial infection: For whom the bell tolls Nature. 395: 217. PMID 9751041 DOI: 10.1038/26104 |
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Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, Rollins BJ. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice Molecular Cell. 2: 275-281. PMID 9734366 DOI: 10.1016/S1097-2765(00)80139-2 |
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Choe H, Martin KA, Farzan M, Sodroski J, Gerard NP, Gerard C. Structural interactions between chemokine receptors, gp120 Env and CD4. Seminars in Immunology. 10: 249-57. PMID 9653051 DOI: 10.1006/Smim.1998.0127 |
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Castagliuolo I, Riegler M, Pasha A, Nikulasson S, Lu B, Gerard C, Gerard NP, Pothoulakis C. Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritis. The Journal of Clinical Investigation. 101: 1547-50. PMID 9541482 DOI: 10.1172/Jci2039 |
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Heesen M, Berman MA, Charest A, Housman D, Gerard C, Dorf ME. Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1. Immunogenetics. 47: 364-70. PMID 9510554 DOI: 10.1007/S002510050371 |
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Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. The Journal of Experimental Medicine. 187: 601-8. PMID 9463410 DOI: 10.1084/Jem.187.4.601 |
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Parolin C, Borsetti A, Choe H, Farzan M, Kolchinsky P, Heesen M, Ma Q, Gerard C, Palu G, Dorf ME, Springer T, Sodroski J. Use of murine CXCR-4 as a second receptor by some T-cell-tropic human immunodeficiency viruses Journal of Virology. 72: 1652-1656. PMID 9445072 DOI: 10.1128/Jvi.72.2.1652-1656.1998 |
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Choe H, Farzan M, Konkel M, Martin K, Sun Y, Marcon L, Cayabyab M, Berman M, Dorf ME, Gerard N, Gerard C, Sodroski J. The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1 Journal of Virology. 72: 6113-6118. DOI: 10.1128/Jvi.72.7.6113-6118.1998 |
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Farzan M, Choe H, Vaca L, Martin K, Sun Y, Desjardins E, Ruffing N, Wu L, Wyatt R, Gerard N, Gerard C, Sodroski J. A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5 Journal of Virology. 72: 1160-1164. DOI: 10.1128/Jvi.72.2.1160-1164.1998 |
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Sabroe I, Hartnell A, Conroy D, Collins P, Gerard N, Gerard C, Ponath P, Williams T. The Role of Eosinophil Chemokine Receptors in Allergic Inflammation in Vivo Clinical Science. 95: 13P-13P. DOI: 10.1042/CS095013P |
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Saria A, Hauser KF, Traurig HH, Turbek CS, Hersh L, Gerard C. Opioid-related changes in nociceptive threshold and in tissue levels of enkephalins after target disruption of the gene for neutral endopeptidase (EC 3.4.24.11) in mice. Neuroscience Letters. 234: 27-30. PMID 9347938 DOI: 10.1016/S0304-3940(97)00660-5 |
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Gerard C, Frossard JL, Bhatia M, Saluja A, Gerard NP, Lu B, Steer M. Targeted disruption of the β-chemokine receptor CCR1 protects against pancreatitis-associated lung injury Journal of Clinical Investigation. 100: 2022-2027. PMID 9329966 DOI: 10.1172/Jci119734 |
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Höpken UE, Lu B, Gerard NP, Gerard C. Impaired Inflammatory Responses in the Reverse Arthus Reaction Through Genetic Deletion of the C5a Receptor Journal of Experimental Medicine. 186: 749-756. PMID 9271590 DOI: 10.1084/Jem.186.5.749 |
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Lu B, Figini M, Emanueli C, Geppetti P, Grady EF, Gerard NP, Ansell J, Payan DG, Gerard C, Bunnett N. The control of microvascular permeability and blood pressure by neutral endopeptidase. Nature Medicine. 3: 904-907. PMID 9256283 DOI: 10.1038/Nm0897-904 |
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Farzan M, Choe H, Martin K, Marcon L, Hofmann W, Karlsson G, Sun Y, Barrett P, Marchand N, Sullivan N, Gerard N, Gerard C, Sodroski J. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection Journal of Experimental Medicine. 186: 405-411. PMID 9236192 DOI: 10.1084/Jem.186.3.405 |
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Figini M, Emanueli C, Grady EF, Kirkwood K, Payan DG, Ansel J, Gerard C, Geppetti P, Bunnett N. Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas. The American Journal of Physiology. 272: G785-93. PMID 9142909 DOI: 10.1152/Ajpgi.1997.272.4.G785 |
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Cundell DR, Gerard C, Idanpaan-Heikkila I, Tuomanen EI, Gerard NP. PAF receptor anchors Streptococcus pneumoniae to activated human endothelial cells Advances in Experimental Medicine and Biology. 416: 89-94. PMID 9131132 DOI: 10.1007/978-1-4899-0179-8_16 |
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Farzan M, Choe H, Martin KA, Sun Y, Sidelko M, Mackay CR, Gerard NP, Sodroski J, Gerard C. HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5. The Journal of Biological Chemistry. 272: 6854-7. PMID 9054370 DOI: 10.1074/Jbc.272.11.6854 |
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Marcon L, Choe H, Martin KA, Farzan M, Ponath PD, Wu L, Newman W, Gerard N, Gerard C, Sodroski J. Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239. Journal of Virology. 71: 2522-7. PMID 9032394 DOI: 10.1128/Jvi.71.3.2522-2527.1997 |
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Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, Borsetti A, Cardoso AA, Desjardin E, Newman W, Gerard C, Sodroski J. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature. 384: 179-83. PMID 8906795 DOI: 10.1038/384179A0 |
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|
| 1996 |
Heesen M, Tanabe S, Berman MA, Yoshizawa I, Luo Y, Kim RJ, Post TW, Gerard C, Dorf ME. Mouse astrocytes respond to the chemokines MCP-1 and KC, but reverse transcriptase-polymerase chain reaction does not detect mRNA for the KC or new MCP-1 receptor. Journal of Neuroscience Research. 45: 382-391. PMID 8872898 DOI: 10.1002/(Sici)1097-4547(19960815)45:4<382::Aid-Jnr7>3.0.Co;2-5 |
0.415 |
|
| 1996 |
Bozic CR, Gerard NP, Gerard C. Receptor binding specificity and pulmonary gene expression of the neutrophil-activating peptide ENA-78. American Journal of Respiratory Cell and Molecular Biology. 14: 302-308. PMID 8845182 DOI: 10.1165/Ajrcmb.14.3.8845182 |
0.366 |
|
| 1996 |
Bozic CR, Lu B, Höpken UE, Gerard C, Gerard NP. Neurogenic amplification of immune complex inflammation Science. 273: 1722-1725. PMID 8781237 DOI: 10.1126/Science.273.5282.1722 |
0.382 |
|
| 1996 |
Höpken UE, Lu B, Gerard NP, Gerard C. The C5a chemoattractant receptor mediates mucosal defence to infection Nature. 383: 86-89. PMID 8779720 DOI: 10.1038/383086A0 |
0.459 |
|
| 1996 |
Ponath PD, Qin S, Post TW, Wang J, Wu L, Gerard NP, Newman W, Gerard C, Mackay CR. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. Journal of Experimental Medicine. 183: 2437-2448. PMID 8676064 DOI: 10.1084/Jem.183.6.2437 |
0.419 |
|
| 1996 |
Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates Cell. 85: 1135-1148. PMID 8674119 DOI: 10.1016/S0092-8674(00)81313-6 |
0.336 |
|
| 1996 |
Lu B, Gerard NP, Kolakowski LF, Finco O, Carroll MC, Gerard C. Neutral endopeptidase modulates septic shock Annals of the New York Academy of Sciences. 780: 156-163. PMID 8602728 DOI: 10.1111/J.1749-6632.1996.Tb15119.X |
0.366 |
|
| 1995 |
Lu B, Gerard NP, Kolakowski LF, Bozza M, Zurakowski D, Finco O, Carroll MC, Gerard C. Neutral endopeptidase modulation of septic shock Journal of Experimental Medicine. 181: 2271-2275. PMID 7760013 DOI: 10.1084/Jem.181.6.2271 |
0.359 |
|
| 1995 |
Kolakowski LF, Lu B, Gerard C, Gerard NP. Probing the 'message:address' sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segments Journal of Biological Chemistry. 270: 18077-18082. PMID 7629117 DOI: 10.1074/Jbc.270.30.18077 |
0.393 |
|
| 1995 |
Cundell DR, Gerard NP, Gerard C, Idanpaan-Heikkila I, Tuomanen EI. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor Nature. 377: 435-438. PMID 7566121 DOI: 10.1038/377435A0 |
0.402 |
|
| 1995 |
Garcia Rodriguez C, Cundell DR, Tuomanen EI, Kolakowski LF, Gerard C, Gerard NP. The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking Journal of Biological Chemistry. 270: 25178-25184. PMID 7559653 DOI: 10.1074/Jbc.270.42.25178 |
0.396 |
|
| 1994 |
Gerard C, Gerard NP. The pro-inflammatory seven-transmembrane segment receptors of the leukocyte. Current Opinion in Immunology. 6: 140-145. PMID 8172674 DOI: 10.1016/0952-7915(94)90045-0 |
0.407 |
|
| 1994 |
Gerard C, Gerard NP. C5A Anaphylatoxin and Its Seven Transmembrane-Segment Receptor Annual Review of Immunology. 12: 775-808. PMID 8011297 DOI: 10.1146/Annurev.Iy.12.040194.004015 |
0.396 |
|
| 1994 |
Asano K, Chee CBE, Gaston B, Lilly CM, Gerard C, Drazen JM, Stamler JS. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 91: 10089-10093. PMID 7524082 DOI: 10.1073/Pnas.91.21.10089 |
0.335 |
|
| 1993 |
Gerard NP, Bao L, Xiao-Ping H, Eddy RL, Shows TB, Gerard C. Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene. Biochemistry. 32: 1243-50. PMID 8383526 DOI: 10.1021/Bi00056A007 |
0.385 |
|
| 1993 |
Gerard NP, Bao L, Xiao-Ping H, Gerard C. Molecular aspects of the tachykinin receptors. Regulatory Peptides. 43: 21-35. PMID 8381237 DOI: 10.1016/0167-0115(93)90404-V |
0.34 |
|
| 1992 |
Bao L, Gerard NP, Eddy RL, Shows TB, Gerard C. Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19. Genomics. 13: 437-440. PMID 1612600 DOI: 10.1016/0888-7543(92)90265-T |
0.362 |
|
| 1992 |
Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N, Snyderman R. Functional high efficiency expression of cloned leucocyte chemoattractant receptor cDNAs Febs Letters. 297: 275-279. PMID 1544408 DOI: 10.1016/0014-5793(92)80555-U |
0.405 |
|
| 1992 |
Iijima H, Gerard NP, Squassoni C, Ewig J, Face D, Drazen JM, Kim YA, Shriver B, Hersh LB, Gerard C. Exon 16 del: a novel form of human neutral endopeptidase (CALLA). The American Journal of Physiology. 262: L725-9. PMID 1535484 DOI: 10.1152/Ajplung.1992.262.6.L725 |
0.306 |
|
| 1991 |
Gerard NP, Gerard C. The chemotactic receptor for human C5a anaphylatoxin Nature. 349: 614-617. PMID 1847994 DOI: 10.1038/349614A0 |
0.44 |
|
| 1991 |
Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N, Snyderman R. Receptor class desensitization of leukocyte chemoattractant receptors. Proceedings of the National Academy of Sciences of the United States of America. 88: 11564-11568. PMID 1763071 DOI: 10.1073/Pnas.88.24.11564 |
0.404 |
|
| 1991 |
Gerard NP, Garraway LA, Eddy RL, Shows TB, Iijima H, Paquet JL, Gerard C. Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. Biochemistry. 30: 10640-10646. PMID 1657150 DOI: 10.1021/Bi00108A006 |
0.377 |
|
| 1990 |
Gerard NP, Gerard C. Construction and expression of a novel recombinant anaphylatoxin, C5a-N19, as a probe for the human C5a receptor Biochemistry. 29: 9274-9281. PMID 2271595 DOI: 10.1021/Bi00491A024 |
0.351 |
|
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