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Henry Brem, MD - Publications

Affiliations: 
1999- Neurosurgery Johns Hopkins University, Baltimore, MD 
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214/449 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kim JE, Lee RP, Yazigi E, Atta L, Feghali J, Pant A, Jain A, Levitan I, Kim E, Patel K, Kannapadi N, Shah P, Bibic A, Hou Z, Caplan JM, ... ... Brem H, et al. Soluble PD-L1 reprograms blood monocytes to prevent cerebral edema and facilitate recovery after ischemic stroke. Brain, Behavior, and Immunity. PMID 38070624 DOI: 10.1016/j.bbi.2023.12.007  0.484
2020 Khalafallah AM, Jimenez AE, Romo CG, Kamson DO, Kleinberg L, Weingart J, Brem H, Grossman SA, Mukherjee D. Quantifying the utility of a multidisciplinary neuro-oncology tumor board. Journal of Neurosurgery. 1-6. PMID 32947258 DOI: 10.3171/2020.5.Jns201299  0.368
2020 Khalafallah AM, Huq S, Jimenez AE, Brem H, Mukherjee D. The 5-factor modified frailty index: an effective predictor of mortality in brain tumor patients. Journal of Neurosurgery. 1-9. PMID 32796147 DOI: 10.3171/2020.5.Jns20766  0.341
2020 Huq S, Casaos J, Serra R, Peters M, Xia Y, Ding AS, Ehresman J, Kedda JN, Morales M, Gorelick NL, Zhao T, Ishida W, Perdomo-Pantoja A, Cecia A, Ji C, ... ... Brem H, et al. Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma. Molecular Cancer Therapeutics. PMID 32606016 DOI: 10.1158/1535-7163.Mct-19-0572  0.324
2020 Jackson C, Choi J, Khalafallah AM, Price C, Bettegowda C, Lim M, Gallia G, Weingart J, Brem H, Mukherjee D. A systematic review and meta-analysis of supratotal versus gross total resection for glioblastoma. Journal of Neuro-Oncology. PMID 32562247 DOI: 10.1007/S11060-020-03556-Y  0.36
2020 El Demerdash N, Kedda J, Ram N, Brem H, Tyler B. Novel therapeutics for brain tumors: current practice and future prospects. Expert Opinion On Drug Delivery. 17: 9-21. PMID 31971041 DOI: 10.1080/17425247.2019.1676227  0.407
2019 Han D, Serra R, Gorelick N, Fatima U, Eberhart CG, Brem H, Tyler B, Steckl AJ. Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor. Scientific Reports. 9: 17936. PMID 31784666 DOI: 10.1038/S41598-019-54283-Y  0.403
2019 Choi J, Rui Y, Kim J, Gorelick N, Wilson DR, Kozielski K, Mangraviti A, Sankey E, Brem H, Tyler B, Green JJ, Jackson EM. Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies. Nanomedicine : Nanotechnology, Biology, and Medicine. 102115. PMID 31655205 DOI: 10.1016/J.Nano.2019.102115  0.373
2019 Smith SJ, Tyler B, Gould TWA, Veal GJ, Gorelick NL, Rowlinson J, Serra R, Ritchie AA, Berry P, Otto A, Choi J, Skuli N, Estevez-Cebrero MA, Shakesheff KM, Brem H, et al. Overall survival in malignant glioma is significantly prolonged by neurosurgical delivery of etoposide and temozolomide from a thermo-responsive biodegradable paste. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31113843 DOI: 10.1158/1078-0432.Ccr-18-3850  0.382
2019 Wu A, Maxwell R, Xia Y, Cardarelli P, Oyasu M, Belcaid Z, Kim E, Hung A, Luksik AS, Garzon-Muvdi T, Jackson CM, Mathios D, Theodros D, Cogswell J, Brem H, et al. Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment. Journal of Neuro-Oncology. PMID 31025274 DOI: 10.1007/S11060-019-03172-5  0.323
2019 Ehresman JS, Garzon-Muvdi T, Rogers D, Lim M, Gallia GL, Weingart J, Brem H, Bettegowda C, Chaichana KL. Risk of Developing Postoperative Deficits Based on Tumor Location after Surgical Resection of an Intracranial Meningioma. Journal of Neurological Surgery. Part B, Skull Base. 80: 59-66. PMID 30733902 DOI: 10.1055/S-0038-1667066  0.333
2019 Huq S, Casaos J, Peters M, Xia Y, Ding A, Morales M, Gorelick N, Serra R, Zhao T, Ishida W, Perdomo-Pantoja A, Cecia A, Ji C, Suk I, Sidransky D, ... ... Brem H, et al. Abstract B06: Repositioning the FDA-approved antiviral drug ribavirin as targeted therapy for nasopharyngeal carcinoma Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-B06  0.346
2019 Serra R, Smith SJ, Rowlinson J, Gorelick NL, Veal GJ, Shakesheff K, Grundy R, Brem H, Rahman R, Tyler B. Local Delivery of the Poly-ADP-Ribose-Polymerase-Inhibitor Olaparib From a Biodegradable Paste Potentiates Radiotherapy and Prolongs Survival Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_641  0.32
2019 Rahman R, Campbell E, Brem H, Pearl M, Green J, Janowski M, Walczak P, Tyler B, Warren K, Singleton W, Mullen A, Boyd M, Veal G, Hargrave D, van Vuurden D, et al. SCIDOT-08. CHILDREN’S BRAIN TUMOUR DRUG DELIVERY CONSORTIUM (CBTDDC) Neuro-Oncology. 21: vi274-vi274. DOI: 10.1093/Neuonc/Noz175.1149  0.305
2019 Smith S, Serra R, Rowlinson J, Gorelick N, Veal G, Shakesheff K, Brem H, Grundy R, Tyler B, Rahman R. P11.60 Neurosurgical delivery of the poly ADP ribose polymerase-1 inhibitor olaparib from a thermo-responsive biodegradable paste potentiates radiotherapy and prolongs survival Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz126.206  0.311
2018 Nicholas SE, Salvatori R, Quinones-Hinojosa A, Redmond K, Gallia G, Lim M, Rigamonti D, Brem H, Kleinberg L. Deferred Radiotherapy After Debulking of Non-functioning Pituitary Macroadenomas: Clinical Outcomes. Frontiers in Oncology. 8: 660. PMID 30687636 DOI: 10.3389/Fonc.2018.00660  0.369
2018 Shapira-Furman T, Serra R, Gorelick N, Doglioli M, Tagliaferri V, Cecia A, Peters M, Kumar A, Rottenberg Y, Langer R, Brem H, Tyler B, Domb AJ. Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 295: 93-101. PMID 30605703 DOI: 10.1016/J.Jconrel.2018.12.048  0.39
2018 Maxwell R, Luksik AS, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Choi J, Theodros D, Jackson CM, Mathios D, Ye X, Tran PT, ... ... Brem H, et al. Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system. Oncoimmunology. 7: e1500108. PMID 30524891 DOI: 10.1080/2162402X.2018.1500108  0.319
2018 Harris-Bookman S, Mathios D, Martin AM, Xia Y, Kim E, Xu H, Belcaid Z, Polanczyk M, Barberi T, Theodros D, Kim J, Taube JM, Burger PC, Selby M, Taitt C, ... ... Brem H, et al. Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma. International Journal of Cancer. PMID 30248181 DOI: 10.1002/Ijc.31661  0.312
2018 Hung AL, Maxwell R, Theodros D, Belcaid Z, Mathios D, Luksik AS, Kim E, Wu A, Xia Y, Garzon-Muvdi T, Jackson C, Ye X, Tyler B, Selby M, Korman A, ... ... Brem H, et al. TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM. Oncoimmunology. 7: e1466769. PMID 30221069 DOI: 10.1080/2162402X.2018.1466769  0.367
2018 Paldor I, Chaichana KL, Brem H, Tyler BM. Targeted Local Therapy for Management of Intracranial High-Grade Gliomas. Progress in Neurological Surgery. 32: 159-171. PMID 29990982 DOI: 10.1159/000469688  0.395
2018 Casaos J, Huq S, Lott T, Felder R, Choi J, Gorelick N, Peters M, Xia Y, Maxwell R, Zhao T, Ji C, Simon T, Sesen J, Scotland SJ, Kast RE, ... ... Brem H, et al. Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors. Oncotarget. 9: 8054-8067. PMID 29487714 DOI: 10.18632/Oncotarget.23883  0.39
2018 Wu A, Cardarelli P, Oyasu M, Menezes D, Ponath P, Cogswell J, Maxwell R, Luksik A, Hung A, Kim E, Belcaid Z, Brem H, Pardoll D, Lim M. Abstract 1736: The combination of CXCR4 and checkpoint receptor inhibition improves survival in an orthotopic murine glioma model Cancer Research. 78: 1736-1736. DOI: 10.1158/1538-7445.Am2018-1736  0.362
2018 Maxwell R, Luksik A, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Theodros D, Jackson C, Ye X, Tran PT, Redmond KJ, Brem H, et al. Impact of Corticosteroids on the Efficacy of Anti-PD-1 Therapy for Tumors Located Within or Outside the Central Nervous System International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.035  0.31
2017 Nabors LB, Portnow J, Ammirati M, Baehring J, Brem H, Butowski N, Fenstermaker RA, Forsyth P, Hattangadi-Gluth J, Holdhoff M, Howard S, Junck L, Kaley T, Kumthekar P, Loeffler JS, et al. NCCN Guidelines Insights: Central Nervous System Cancers, Version 1.2017. Journal of the National Comprehensive Cancer Network : Jnccn. 15: 1331-1345. PMID 29118226 DOI: 10.6004/Jnccn.2017.0166  0.304
2017 Mangraviti A, Raghavan T, Volpin F, Skuli N, Gullotti D, Zhou J, Asnaghi L, Sankey E, Liu A, Wang Y, Lee DH, Gorelick N, Serra R, Peters M, Schriefer D, ... ... Brem H, et al. HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy. Scientific Reports. 7: 14978. PMID 29097800 DOI: 10.1038/S41598-017-14990-W  0.378
2017 Ehresman JS, Garzon-Muvdi T, Rogers D, Lim M, Gallia GL, Weingart J, Brem H, Bettegowda C, Chaichana KL. The relevance of Simpson grade resectionsin the modern neurosurgical treatment of World Health Organization Grade 1, 2, and 3meningiomas. World Neurosurgery. PMID 29042332 DOI: 10.1016/j.wneu.2017.10.028  0.315
2017 Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM. The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma. Journal of Neuro-Oncology. PMID 28735458 DOI: 10.1007/S11060-017-2567-9  0.339
2017 Wu A, Weingart JD, Gallia GL, Lim M, Brem H, Bettegowda C, Chaichana KL. Risk Factors for Preoperative Seizures and Loss of Seizure Control in Patients Undergoing Surgery for Metastatic Brain Tumors. World Neurosurgery. PMID 28512046 DOI: 10.1016/J.Wneu.2017.05.028  0.345
2017 Garzon-Muvdi T, Yang W, Lim M, Brem H, Huang J. Atypical and anaplastic meningioma: outcomes in a population based study. Journal of Neuro-Oncology. PMID 28429237 DOI: 10.1007/S11060-017-2436-6  0.381
2017 Zhang C, Nance EA, Mastorakos P, Chisholm J, Berry S, Eberhart C, Tyler B, Brem H, Suk JS, Hanes J. Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28279797 DOI: 10.1016/J.Jconrel.2017.03.007  0.392
2017 Kessler RA, Garzon-Muvdi T, Yang W, Weingart J, Olivi A, Huang J, Brem H, Lim M. Metastatic Atypical and Anaplastic Meningioma: A Case Series and Review of the Literature. World Neurosurgery. PMID 28143726 DOI: 10.1016/J.Wneu.2017.01.070  0.318
2017 Smith S, Gould T, Tyler B, Ritchie A, Veal G, Shakesheff K, Brem H, Grundy R, Rahman R. Surg-24. Overall Survival In A Syngeneic Rodent Orthotopic High-Grade Glioma Model Is Significantly Prolonged By Neurosurgical Delivery Of Plga/Peg Interstitial Chemotherapy Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.979  0.341
2017 Smith S, Tyler B, Gould T, Veal G, Ritchie A, Berry P, Otto A, Rowlinson J, Choi J, Skuli N, Shakesheff K, Brem H, Grundy R, Rahman R. Scdt-10. Overall Survival In An Orthotopic Malignant Glioma Model Is Significantly Prolonged By Neurosurgical Delivery Of Plga/Peg Interstitial Chemotherapy Paste Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.1093  0.347
2017 Smith S, Gould T, Tyler B, Veal G, Ritchie A, Gorelick N, Choi J, Skuli N, Shakesheff K, Brem H, Grundy R, Rahman R. Trth-21. Glioma Survival Benefits From Neurosurgical Delivery Of Plga/Peg Interstitial Therapy Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox083.232  0.326
2017 Rahman R, Grundy R, Campbell E, Brem H, Pearl M, Green J, Janoski M, Cohen K, Walczak P, Warren K, Lowis S, Mullen A, Boyd M, Veal G, Hargrave D, et al. Children's brain tumour drug delivery consortium Neuro-Oncology. 19: 0. DOI: 10.1093/Neuonc/Nox083.218  0.308
2016 Mathios D, Kim JE, Mangraviti A, Phallen J, Park CK, Jackson CM, Garzon-Muvdi T, Kim E, Theodros D, Polanczyk M, Martin AM, Suk I, Ye X, Tyler B, Bettegowda C, ... Brem H, et al. Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM. Science Translational Medicine. 8: 370ra180. PMID 28003545 DOI: 10.1126/Scitranslmed.Aag2942  0.342
2016 Volpin F, Casaos J, Sesen J, Mangraviti A, Choi J, Gorelick N, Frikeche J, Lott T, Felder R, Scotland SJ, Eisinger-Mathason TS, Brem H, Tyler B, Skuli N. Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic. Oncogene. PMID 27941882 DOI: 10.1038/Onc.2016.457  0.39
2016 Mangraviti A, Tzeng SY, Gullotti D, Kozielski KL, Kim JE, Seng M, Abbadi S, Schiapparelli P, Sarabia-Estrada R, Vescovi A, Brem H, Olivi A, Tyler B, Green JJ, Quinones-Hinojosa A. Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival. Biomaterials. 100: 53-66. PMID 27240162 DOI: 10.1016/J.Biomaterials.2016.05.025  0.376
2016 Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM, Lim M, Weingart JD, Quinones-Hinojosa A, Bettegowda C, Kassam AB, Olivi A, Brem H, Riggins GJ, Gallia GL. Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines. Plos One. 11: e0150271. PMID 27028405 DOI: 10.1371/Journal.Pone.0150271  0.3
2016 Mangraviti A, Gullotti D, Tyler B, Brem H. Nanobiotechnology-based delivery strategies: New frontiers in brain tumor targeted therapies. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27016141 DOI: 10.1016/J.Jconrel.2016.03.031  0.402
2016 Upadhyay UM, Tyler B, Patta Y, Wicks R, Spencer K, Scott A, Masi B, Hwang L, Grossman R, Cima M, Brem H, Langer R. Correction: Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 45 (16071-16076) DOI: 10.1073/pnas.1313420110) Proceedings of the National Academy of Sciences of the United States of America. 113: E1327. DOI: 10.1073/Pnas.1600771113  0.302
2015 Jackson S, Anders NM, Mangraviti A, Wanjiku TM, Sankey EW, Liu A, Brem H, Tyler B, Rudek MA, Grossman SA. The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain. Journal of Neuro-Oncology. PMID 26626489 DOI: 10.1007/S11060-015-1998-4  0.326
2015 De la Garza-Ramos R, Kerezoudis P, Tamargo RJ, Brem H, Huang J, Bydon M. Surgical complications following malignant brain tumor surgery: An analysis of 2002-2011 data. Clinical Neurology and Neurosurgery. 140: 6-10. PMID 26615463 DOI: 10.1016/J.Clineuro.2015.11.005  0.354
2015 Jackson CM, Kochel CM, Nirschl CJ, Durham NM, Ruzevick J, Alme A, Francica BJ, Elias J, Daniels A, Dubensky TW, Lauer P, Brockstedt D, Baxi EG, Calabresi PA, Taube JM, ... ... Brem H, et al. Systemic Tolerance Mediated by Melanoma Brain Tumors is Reversible by Radiotherapy and Vaccination. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26490306 DOI: 10.1158/1078-0432.Ccr-15-1516  0.351
2015 Nabors LB, Portnow J, Ammirati M, Baehring J, Brem H, Brown P, Butowski N, Chamberlain MC, Fenstermaker RA, Friedman A, Gilbert MR, Hattangadi-Gluth J, Holdhoff M, Junck L, Kaley T, et al. Central Nervous System Cancers, Version 1.2015. Journal of the National Comprehensive Cancer Network : Jnccn. 13: 1191-202. PMID 26483059 DOI: 10.6004/Jnccn.2015.0148  0.334
2015 Grossman R, Burger P, Soudry E, Tyler B, Chaichana KL, Weingart J, Olivi A, Gallia GL, Sidransky D, Quiñones-Hinojosa A, Ye X, Brem H. MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 26249244 DOI: 10.1016/J.Jocn.2015.07.003  0.301
2015 Wang Y, Springer S, Zhang M, McMahon KW, Kinde I, Dobbyn L, Ptak J, Brem H, Chaichana K, Gallia GL, Gokaslan ZL, Groves ML, Jallo GI, Lim M, Olivi A, et al. Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195750 DOI: 10.1073/Pnas.1511694112  0.349
2015 Sesen J, Dahan P, Scotland SJ, Saland E, Dang VT, Lemarié A, Tyler BM, Brem H, Toulas C, Cohen-Jonathan Moyal E, Sarry JE, Skuli N. Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response. Plos One. 10: e0123721. PMID 25867026 DOI: 10.1371/Journal.Pone.0123721  0.369
2015 Chaichana KL, Pinheiro L, Brem H. Delivery of local therapeutics to the brain: working toward advancing treatment for malignant gliomas. Therapeutic Delivery. 6: 353-69. PMID 25853310 DOI: 10.4155/Tde.14.114  0.406
2015 Zhang F, Mastorakos P, Mishra MK, Mangraviti A, Hwang L, Zhou J, Hanes J, Brem H, Olivi A, Tyler B, Kannan RM. Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers. Biomaterials. 52: 507-16. PMID 25818456 DOI: 10.1016/J.Biomaterials.2015.02.053  0.395
2015 Mangraviti A, Tyler B, Brem H. Interstitial chemotherapy for malignant glioma: Future prospects in the era of multimodal therapy. Surgical Neurology International. 6: S78-84. PMID 25722936 DOI: 10.4103/2152-7806.151345  0.417
2015 Mangraviti A, Tzeng SY, Kozielski KL, Wang Y, Jin Y, Gullotti D, Pedone M, Buaron N, Liu A, Wilson DR, Hansen SK, Rodriguez FJ, Gao GD, DiMeco F, Brem H, et al. Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo. Acs Nano. 9: 1236-49. PMID 25643235 DOI: 10.1021/Nn504905Q  0.34
2015 Wicks RT, Azadi J, Mangraviti A, Zhang I, Hwang L, Joshi A, Bow H, Hutt-Cabezas M, Martin KL, Rudek MA, Zhao M, Brem H, Tyler BM. Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma. Neuro-Oncology. 17: 70-80. PMID 25053853 DOI: 10.1093/Neuonc/Nou143  0.312
2015 Jackson S, Anders N, Mangraviti A, Wanjiku T, Brem H, Tyler B, Rudek MA, Grossman SA. The effect of regadenoson-induced transient disruption of the blood brain barrier on temozolomide delivery to rat brain parenchyma. Journal of Clinical Oncology. 33: 2066-2066. DOI: 10.1200/Jco.2015.33.15_Suppl.2066  0.345
2015 Mathios D, Kim J, Phallen J, Mangraviti A, Park C, Theodros D, Jackson C, Garzon-Muvdi T, Kim E, Ye X, Tyler B, Brem H, Pardoll D, Lim M. Optimizing the delivery of chemotherapy in the setting of immunotherapy in a preclinical glioblastoma model Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P307  0.334
2015 Mathios D, Hwang T, Phallen J, Bettewgoda C, Ha P, Burger P, Brem H, McDonald K, Park C, Lim M. Abstract 3839: Investigation of epigenetic based inter-tumoral heterogeneity identifies novel ZMIZ1 gene as a biomarker of cancer patient survival in multiple tumor types Cancer Research. 75: 3839-3839. DOI: 10.1158/1538-7445.Am2015-3839  0.367
2015 Kim JE, Patel MA, Mangraviti A, Polanczyk M, Kim ES, Theodros D, Velarde E, Liu A, Sankey E, Mathios D, Jackson CM, Olivi A, Tran P, Drake CG, Tyler B, ... ... Brem H, et al. Imps-20Combination Therapy With Anti-Pd-1, Anti-Tim-3, And Focal Radiation Results In Regression Of Murine Gliomas Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov217.20  0.303
2015 Mangraviti A, Tzeng S, Gullotti D, Kozielski K, Kim J, Seng M, Abbadi S, Schiapparelli P, Sarabia-Estrada R, Brem H, Tyler B, Olivi A, Green J, Quinones-Hinojosa A. ATPS-90EFFICACY OF NON-VIRAL ENGINEERED ADIPOSE MESENCHYMAL STEM CELLS FOR BRAIN TUMOR THERAPY Neuro-Oncology. 17: v38.2-v38. DOI: 10.1093/Neuonc/Nov204.90  0.38
2015 Mangraviti A, Raghavan T, Volpin F, Skuli N, Zhou J, Eberhart C, Rodriguez F, Sankey E, Gullotti D, Liu A, Wang Y, Schriefer D, Brem H, Olivi A, Tyler B. ATPS-89LOCAL DELIVERY OF A SMALL-MOLECULE INHIBITOR OF HYPOXIA INDUCIBLE FACTOR-1: A NEW CANDIDATE DRUG FOR BRAIN TUMOR THERAPY Neuro-Oncology. 17: v38.1-v38. DOI: 10.1093/Neuonc/Nov204.89  0.444
2015 Jackson S, Anders N, Mangraviti A, Brem H, Tyler B, Rudek M, Grossman S. Tr-09The Effect Of Regadenoson-Induced Transient Disruption Of The Blood Brain Barrier On Temozolomide Delivery To Rat Brain Parenchyma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.154  0.338
2014 Bydon M, Abt NB, Macki M, Brem H, Huang J, Bydon A, Tamargo RJ. Preoperative anemia increases postoperative morbidity in elective cranial neurosurgery. Surgical Neurology International. 5: 156. PMID 25422784 DOI: 10.4103/2152-7806.143754  0.304
2014 Nabors LB, Portnow J, Ammirati M, Brem H, Brown P, Butowski N, Chamberlain MC, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hattangadi-Gluth J, Hesser D, Holdhoff M, Junck L, et al. Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines. Journal of the National Comprehensive Cancer Network : Jnccn. 12: 1517-23. PMID 25361798 DOI: 10.6004/Jnccn.2014.0151  0.344
2014 Upadhyay UM, Tyler B, Patta Y, Wicks R, Spencer K, Scott A, Masi B, Hwang L, Grossman R, Cima M, Brem H, Langer R. Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. Proceedings of the National Academy of Sciences of the United States of America. 111: 16071-6. PMID 25349381 DOI: 10.1073/Pnas.1313420110  0.409
2014 Woodworth GF, Dunn GP, Nance EA, Hanes J, Brem H. Emerging insights into barriers to effective brain tumor therapeutics. Frontiers in Oncology. 4: 126. PMID 25101239 DOI: 10.3389/Fonc.2014.00126  0.411
2014 Belcaid Z, Phallen JA, Zeng J, See AP, Mathios D, Gottschalk C, Nicholas S, Kellett M, Ruzevick J, Jackson C, Albesiano E, Durham NM, Ye X, Tran PT, Tyler B, ... ... Brem H, et al. Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. Plos One. 9: e101764. PMID 25013914 DOI: 10.1371/Journal.Pone.0101764  0.34
2014 Gabikian P, Tyler BM, Zhang I, Li KW, Brem H, Walter KA. Radiosensitization of malignant gliomas following intracranial delivery of paclitaxel biodegradable polymer microspheres. Journal of Neurosurgery. 120: 1078-85. PMID 24605841 DOI: 10.3171/2014.1.Jns13235  0.35
2014 Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Science Translational Medicine. 6: 224ra24. PMID 24553385 DOI: 10.1126/Scitranslmed.3007094  0.333
2014 Yohay K, Tyler B, Weaver KD, Pardo AC, Gincel D, Blakeley J, Brem H, Rothstein JD. Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models. Journal of Neurosurgery. 120: 854-63. PMID 24484234 DOI: 10.3171/2013.12.Jns13641  0.377
2014 Bydon M, Ma TM, Xu R, Weingart J, Olivi A, Gokaslan ZL, Tamargo RJ, Brem H, Bydon A. Surgical outcomes of craniocervial junction meningiomas: a series of 22 consecutive patients. Clinical Neurology and Neurosurgery. 117: 71-9. PMID 24438809 DOI: 10.1016/J.Clineuro.2013.11.023  0.539
2014 Bow H, Hwang LS, Schildhaus N, Xing J, Murray L, Salditch Q, Ye X, Zhang Y, Weingart J, Brem H, Tyler B. Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma. Journal of Neurosurgery. 120: 662-9. PMID 24359008 DOI: 10.3171/2013.11.Jns13556  0.391
2014 Chaichana KL, Jusue-Torres I, Navarro-Ramirez R, Raza SM, Pascual-Gallego M, Ibrahim A, Hernandez-Hermann M, Gomez L, Ye X, Weingart JD, Olivi A, Blakeley J, Gallia GL, Lim M, Brem H, et al. Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma. Neuro-Oncology. 16: 113-22. PMID 24285550 DOI: 10.1093/Neuonc/Not137  0.353
2014 Grossman R, Brastianos H, Blakeley JO, Mangraviti A, Lal B, Zadnik P, Hwang L, Wicks RT, Goodwin RC, Brem H, Tyler B. Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models. Journal of Neuro-Oncology. 116: 59-65. PMID 24185441 DOI: 10.1007/S11060-013-1268-2  0.374
2014 Chaichana KL, Acharya S, Flores M, Wijesekera O, Rigamonti D, Weingart JD, Olivi A, Bettegowda C, Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Identifying better surgical candidates among recursive partitioning analysis class 2 patients who underwent surgery for intracranial metastases. World Neurosurgery. 82: e267-75. PMID 24076052 DOI: 10.1016/J.Wneu.2013.08.031  0.355
2014 Chaichana KL, Rao K, Gadkaree S, Dangelmajer S, Bettegowda C, Rigamonti D, Weingart J, Olivi A, Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Factors associated with survival and recurrence for patients undergoing surgery of cerebellar metastases. Neurological Research. 36: 13-25. PMID 24070068 DOI: 10.1179/1743132813Y.0000000260  0.361
2014 Mangraviti A, Tzeng S, Seng M, Abbadi S, Kozielski K, Schiapparelli P, Wijesekera O, Sarabia-Estrada R, Brem H, Tyler B, Olivi A, Green J, Quinones-Hinojosa A. SC-17 * BMP4-SECRETING hAdMSCs ENGINEERED WITH NANOPARTICLES: A NON-VIRAL MSC-BASED THERAPY FOR GLIOBLASTOMA Neuro-Oncology. 16: v200-v201. DOI: 10.1093/Neuonc/Nou275.17  0.314
2014 Mathios D, Phallen J, Park C, Jackson C, Nicholas S, Tyler B, Pardoll D, Brem H, Lim M. It-21Pd-1 Blockade Shows Synergistic Survival, Anti-Tumor Immune Response And Long-Term Memory With Interstitial But Not Systemic Chemotherapy: Study In A Murine Glioblastoma Model. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou258.19  0.312
2014 Mangraviti A, Sengupta S, Paldor I, Rowshanshad D, Sampath P, Olivi A, Tyler B, Brem H. IT-20OVEREXPRESSION OF IL13Ra2: ASSESSMENT OF PRO-AGGRESSIVE AND PRO-INVASIVE PHENOTYPES OF MALIGNANT GLIOMA IN A SYNGENEIC ANIMAL MODEL Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou258.18  0.33
2014 Mangraviti A, Jin Y, Sy J, Wang Y, Raghavan T, Hastings-Spaine L, Olivi A, Tyler B, Brem H. ET-37 * EFFICACY OF INTRACRANIAL DELIVERY OF DICHLOROACETATE AND CARBOPLATIN VIA AN LCP POLYMER MICROCAPSULE DEVICE IN AN EXPERIMENTAL GLIOMA MODEL Neuro-Oncology. 16: v87-v87. DOI: 10.1093/Neuonc/Nou255.37  0.378
2013 Baia GS, Caballero OL, Ho JS, Zhao Q, Cohen T, Binder ZA, Salmasi V, Gallia GL, Quinones-Hinojosa A, Olivi A, Brem H, Burger P, Strausberg RL, Simpson AJ, Eberhart CG, et al. NY-ESO-1 expression in meningioma suggests a rationale for new immunotherapeutic approaches. Cancer Immunology Research. 1: 296-302. PMID 24777967 DOI: 10.1158/2326-6066.Cir-13-0029  0.332
2013 Chaichana KL, Flores M, Acharya S, Sampognaro P, Bettegowda C, Rigamonti D, Weingart JD, Olivi A, Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Survival and recurrence for patients undergoing surgery of skull base intracranial metastases. Journal of Neurological Surgery. Part B, Skull Base. 74: 228-35. PMID 24436917 DOI: 10.1055/S-0033-1342925  0.371
2013 Chaichana KL, Gadkaree S, Rao K, Link T, Rigamonti D, Purtell M, Browner I, Weingart J, Olivi A, Gallia G, Bettegowda C, Brem H, Lim M, Quinones-Hinojosa A. Patients undergoing surgery of intracranial metastases have different outcomes based on their primary pathology. Neurological Research. 35: 1059-69. PMID 24070329 DOI: 10.1179/1743132813Y.0000000253  0.388
2013 Nabors LB, Ammirati M, Bierman PJ, Brem H, Butowski N, Chamberlain MC, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hesser D, Holdhoff M, Junck L, Lawson R, Loeffler JS, et al. Central nervous system cancers. Journal of the National Comprehensive Cancer Network : Jnccn. 11: 1114-51. PMID 24029126 DOI: 10.6004/Jnccn.2013.0132  0.399
2013 Sattler R, Tyler B, Hoover B, Coddington LT, Recinos V, Hwang L, Brem H, Rothstein JD. Increased expression of glutamate transporter GLT-1 in peritumoral tissue associated with prolonged survival and decreases in tumor growth in a rat model of experimental malignant glioma. Journal of Neurosurgery. 119: 878-86. PMID 23909244 DOI: 10.3171/2013.6.Jns122319  0.304
2013 Chaichana KL, Martinez-Gutierrez JC, De la Garza-Ramos R, Weingart JD, Olivi A, Gallia GL, Lim M, Brem H, Quinones-Hinojosa A. Factors associated with survival for patients with glioblastoma with poor pre-operative functional status. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 20: 818-23. PMID 23639620 DOI: 10.1016/J.Jocn.2012.07.016  0.357
2013 Zeng J, See AP, Phallen J, Jackson CM, Belcaid Z, Ruzevick J, Durham N, Meyer C, Harris TJ, Albesiano E, Pradilla G, Ford E, Wong J, Hammers HJ, Mathios D, ... ... Brem H, et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. International Journal of Radiation Oncology, Biology, Physics. 86: 343-9. PMID 23462419 DOI: 10.1016/J.Ijrobp.2012.12.025  0.338
2013 Chaichana KL, Pendleton C, Jackson C, Martinez-Gutierrez JC, Diaz-Stransky A, Aguayo J, Olivi A, Weingart J, Gallia G, Lim M, Brem H, Quinones-Hinojosa A. Deep venous thrombosis and pulmonary embolisms in adult patients undergoing craniotomy for brain tumors. Neurological Research. 35: 206-11. PMID 23336127 DOI: 10.1179/1743132812Y.0000000126  0.341
2013 Vellimana AK, Recinos VR, Hwang L, Fowers KD, Li KW, Zhang Y, Okonma S, Eberhart CG, Brem H, Tyler BM. Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model. Journal of Neuro-Oncology. 111: 229-36. PMID 23224713 DOI: 10.1007/S11060-012-1014-1  0.349
2013 Chaichana KL, Zadnik P, Weingart JD, Olivi A, Gallia GL, Blakeley J, Lim M, Brem H, Quiñones-Hinojosa A. Multiple resections for patients with glioblastoma: prolonging survival. Journal of Neurosurgery. 118: 812-20. PMID 23082884 DOI: 10.3171/2012.9.Jns1277  0.381
2012 Chaichana KL, Jackson C, Patel A, Miller NR, Subramanian P, Lim M, Gallia G, Olivi A, Weingart J, Brem H, Quiñones-Hinojosa A. Predictors of visual outcome following surgical resection of medial sphenoid wing meningiomas. Journal of Neurological Surgery. Part B, Skull Base. 73: 321-6. PMID 24083123 DOI: 10.1055/S-0032-1321510  0.319
2012 Rege A, Seifert AC, Schlattman D, Ouyang Y, Li KW, Basaldella L, Brem H, Tyler BM, Thakor NV. Longitudinal in vivo monitoring of rodent glioma models through thinned skull using laser speckle contrast imaging. Journal of Biomedical Optics. 17: 126017. PMID 23235836 DOI: 10.1117/1.Jbo.17.12.126017  0.351
2012 Momin EN, Adams H, Shinohara RT, Frangakis C, Brem H, Quiñones-Hinojosa A. Postoperative mortality after surgery for brain tumors by patient insurance status in the United States. Archives of Surgery (Chicago, Ill. : 1960). 147: 1017-24. PMID 23165616 DOI: 10.1001/Archsurg.2012.1459  0.329
2012 Grossman R, Tyler B, Brem H, Eberhart CG, Wang S, Fu DX, Wen Z, Zhou J. Growth properties of SF188/V+ human glioma in rats in vivo observed by magnetic resonance imaging. Journal of Neuro-Oncology. 110: 315-23. PMID 23011120 DOI: 10.1007/S11060-012-0974-5  0.31
2012 Grossman R, Rudek MA, Brastianos H, Zadnik P, Brem H, Tyler B, Blakeley JO. The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas. Cancer Chemotherapy and Pharmacology. 70: 129-39. PMID 22644796 DOI: 10.1007/S00280-012-1867-1  0.323
2012 Tyler BM, Hdeib A, Caplan J, Legnani FG, Fowers KD, Brem H, Jallo G, Pradilla G. Delayed onset of paresis in rats with experimental intramedullary spinal cord gliosarcoma following intratumoral administration of the paclitaxel delivery system OncoGel. Journal of Neurosurgery. Spine. 16: 93-101. PMID 22208429 DOI: 10.3171/2011.9.Spine11435  0.314
2011 Grossman R, Tyler B, Hwang L, Zadnik P, Lal B, Javaherian K, Brem H. Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin. Journal of Neurosurgery. 115: 1139-46. PMID 21923243 DOI: 10.3171/2011.8.Jns11125  0.402
2011 Chaichana KL, Zaidi H, Pendleton C, McGirt MJ, Grossman R, Weingart JD, Olivi A, Quiñones-Hinojosa A, Brem H. The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival. Neurological Research. 33: 759-64. PMID 21756557 DOI: 10.1179/1743132811Y.0000000006  0.325
2011 Tyler B, Wadsworth S, Recinos V, Mehta V, Vellimana A, Li K, Rosenblatt J, Do H, Gallia GL, Siu IM, Wicks RT, Rudek MA, Zhao M, Brem H. Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats. Neuro-Oncology. 13: 700-9. PMID 21727209 DOI: 10.1093/Neuonc/Nor050  0.396
2011 Grossman R, Mukherjee D, Chang DC, Bennett R, Brem H, Olivi A, Quiñones-Hinojosa A. Preoperative charlson comorbidity score predicts postoperative outcomes among older intracranial meningioma patients. World Neurosurgery. 75: 279-85. PMID 21492731 DOI: 10.1016/J.Wneu.2010.09.003  0.305
2011 Brem SS, Bierman PJ, Brem H, Butowski N, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hesser D, Junck L, Linette GP, Loeffler JS, Maor MH, et al. Central nervous system cancers. Journal of the National Comprehensive Cancer Network : Jnccn. 9: 352-400. PMID 21464144 DOI: 10.6004/Jnccn.2011.0036  0.399
2011 Chaichana KL, Chaichana KK, Olivi A, Weingart JD, Bennett R, Brem H, Quiñones-Hinojosa A. Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article. Journal of Neurosurgery. 114: 587-94. PMID 20887095 DOI: 10.3171/2010.8.Jns1081  0.324
2011 Grossman R, Mukherjee D, Chang DC, Purtell M, Lim M, Brem H, Quiñones-Hinojosa A. Predictors of inpatient death and complications among postoperative elderly patients with metastatic brain tumors. Annals of Surgical Oncology. 18: 521-8. PMID 20809176 DOI: 10.1245/S10434-010-1299-2  0.342
2011 Chaichana KL, Halthore AN, Parker SL, Olivi A, Weingart JD, Brem H, Quinones-Hinojosa A. Factors involved in maintaining prolonged functional independence following supratentorial glioblastoma resection. Clinical article. Journal of Neurosurgery. 114: 604-12. PMID 20524825 DOI: 10.3171/2010.4.Jns091340  0.318
2010 McGirt MJ, Brem H. Carmustine wafers (Gliadel) plus concomitant temozolomide therapy after resection of malignant astrocytoma: growing evidence for safety and efficacy. Annals of Surgical Oncology. 17: 1729-31. PMID 20422453 DOI: 10.1245/S10434-010-1092-2  0.356
2010 Chaichana KL, Kosztowski T, Niranjan A, Olivi A, Weingart JD, Laterra J, Brem H, Quiñones-Hinojosa A. Prognostic significance of contrast-enhancing anaplastic astrocytomas in adults. Journal of Neurosurgery. 113: 286-92. PMID 20302391 DOI: 10.3171/2010.2.Jns091010  0.33
2010 Recinos VR, Tyler BM, Bekelis K, Sunshine SB, Vellimana A, Li KW, Brem H. Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model. Neurosurgery. 66: 530-7; discussion 53. PMID 20173548 DOI: 10.1227/01.Neu.0000365263.14725.39  0.362
2010 Tyler B, Fowers KD, Li KW, Recinos VR, Caplan JM, Hdeib A, Grossman R, Basaldella L, Bekelis K, Pradilla G, Legnani F, Brem H. A thermal gel depot for local delivery of paclitaxel to treat experimental brain tumors in rats. Journal of Neurosurgery. 113: 210-7. PMID 20001591 DOI: 10.3171/2009.11.Jns08162  0.363
2010 Chaichana KL, McGirt MJ, Woodworth GF, Datoo G, Tamargo RJ, Weingart J, Olivi A, Brem H, Quinones-Hinojosa A. Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas. Neurological Research. 32: 442-8. PMID 19589201 DOI: 10.1179/174313209X431101  0.378
2010 Doucette TA, Kong L, Yang Y, Wei J, Wang J, Fuller GN, Heimberger AB, Rao G, Ajewung N, Kamnasaran D, Katz AM, Amankulor N, Squatrito M, Hambardzumyan D, Holland EC, ... ... Brem H, et al. Tumor Models (In Vivo/In Vitro) Neuro-Oncology. 12: iv130-iv136. DOI: 10.1093/Neuonc/Noq116.S20  0.333
2009 Slager J, Tyler B, Shikanov A, Domb AJ, Shogen K, Sidransky D, Brem H. Local controlled delivery of anti-neoplastic RNAse to the brain. Pharmaceutical Research. 26: 1838-46. PMID 19415468 DOI: 10.1007/S11095-009-9893-3  0.359
2009 McGirt MJ, Than KD, Weingart JD, Chaichana KL, Attenello FJ, Olivi A, Laterra J, Kleinberg LR, Grossman SA, Brem H, Quiñones-Hinojosa A. Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme. Journal of Neurosurgery. 110: 583-8. PMID 19046047 DOI: 10.3171/2008.5.17557  0.365
2009 McGirt MJ, Chaichana KL, Gathinji M, Attenello FJ, Than K, Olivi A, Weingart JD, Brem H, Quiñones-Hinojosa AR. Independent association of extent of resection with survival in patients with malignant brain astrocytoma. Journal of Neurosurgery. 110: 156-62. PMID 18847342 DOI: 10.3171/2008.4.17536  0.363
2008 McGirt MJ, Chaichana KL, Attenello FJ, Weingart JD, Than K, Burger PC, Olivi A, Brem H, Quinoñes-Hinojosa A. Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. Neurosurgery. 63: 700-7; author reply . PMID 18981880 DOI: 10.1227/01.Neu.0000325729.41085.73  0.34
2008 Attenello FJ, Mukherjee D, Datoo G, McGirt MJ, Bohan E, Weingart JD, Olivi A, Quinones-Hinojosa A, Brem H. Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience. Annals of Surgical Oncology. 15: 2887-93. PMID 18636295 DOI: 10.1245/S10434-008-0048-2  0.354
2008 Sonabend AM, Velicu S, Ulasov IV, Han Y, Tyler B, Brem H, Matar MM, Fewell JG, Anwer K, Lesniak MS. A safety and efficacy study of local delivery of interleukin-12 transgene by PPC polymer in a model of experimental glioma. Anti-Cancer Drugs. 19: 133-42. PMID 18176109 DOI: 10.1097/Cad.0B013E3282F24017  0.368
2007 Marupudi NI, Han JE, Li KW, Renard VM, Tyler BM, Brem H. Paclitaxel: a review of adverse toxicities and novel delivery strategies. Expert Opinion On Drug Safety. 6: 609-21. PMID 17877447 DOI: 10.1517/14740338.6.5.609  0.368
2007 Kominsky SL, Tyler B, Sosnowski J, Brady K, Doucet M, Nell D, Smedley JG, McClane B, Brem H, Sukumar S. Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis. Cancer Research. 67: 7977-82. PMID 17804705 DOI: 10.1158/0008-5472.Can-07-1314  0.369
2007 Chaichana KL, Capilla-Gonzalez V, Gonzalez-Perez O, Pradilla G, Han J, Olivi A, Brem H, Garcia-Verdugo JM, Quiñones-Hinojosa A. Preservation of glial cytoarchitecture from ex vivo human tumor and non-tumor cerebral cortical explants: A human model to study neurological diseases. Journal of Neuroscience Methods. 164: 261-70. PMID 17580092 DOI: 10.1016/J.Jneumeth.2007.05.008  0.363
2007 Brem S, Tyler B, Li K, Pradilla G, Legnani F, Caplan J, Brem H. Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model. Cancer Chemotherapy and Pharmacology. 60: 643-50. PMID 17256133 DOI: 10.1007/S00280-006-0407-2  0.317
2007 Lawson HC, Sampath P, Bohan E, Park MC, Hussain N, Olivi A, Weingart J, Kleinberg L, Brem H. Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience. Journal of Neuro-Oncology. 83: 61-70. PMID 17171441 DOI: 10.1007/S11060-006-9303-1  0.409
2006 Fruehauf JP, Brem H, Brem S, Sloan A, Barger G, Huang W, Parker R. In vitro drug response and molecular markers associated with drug resistance in malignant gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4523-32. PMID 16899598 DOI: 10.1158/1078-0432.Ccr-05-1830  0.304
2006 Caplan J, Pradilla G, Hdeib A, Tyler BM, Legnani FG, Bagley CA, Brem H, Jallo G. A novel model of intramedullary spinal cord tumors in rats: functional progression and histopathological characterization. Neurosurgery. 59: 193-200; discussion . PMID 16823316 DOI: 10.1227/01.Neu.0000219276.44563.Da  0.311
2006 Sampath P, Rhines LD, DiMeco F, Tyler BM, Park MC, Brem H. Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma. Journal of Neuro-Oncology. 80: 9-17. PMID 16636748 DOI: 10.1007/S11060-006-9159-4  0.414
2006 Legnani FG, Pradilla G, Thai QA, Fiorindi A, Recinos PF, Tyler BM, Gaini SM, DiMeco F, Brem H, Olivi A. Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers. Journal of Neuro-Oncology. 77: 225-32. PMID 16609837 DOI: 10.1007/S11060-005-6937-3  0.364
2006 Pradilla G, Wang PP, Gabikian P, Li K, Magee CA, Walter KA, Brem H. Local intracerebral administration of Paclitaxel with the paclimer delivery system: toxicity study in a canine model. Journal of Neuro-Oncology. 76: 131-8. PMID 16284923 DOI: 10.1007/S11060-005-5531-Z  0.304
2005 Mavinkurve G, Pradilla G, Legnani FG, Tyler BM, Bagley CA, Brem H, Jallo G. A novel intramedullary spinal cord tumor model: functional, radiological, and histopathological characterization. Journal of Neurosurgery. Spine. 3: 142-8. PMID 16370303 DOI: 10.3171/Spi.2005.3.2.0142  0.322
2005 Lesniak MS, Upadhyay U, Goodwin R, Tyler B, Brem H. Local delivery of doxorubicin for the treatment of malignant brain tumors in rats. Anticancer Research. 25: 3825-31. PMID 16312042  0.31
2005 Pradilla G, Legnani FG, Petrangolini G, Francescato P, Chillemi F, Tyler BM, Gaini SM, Brem H, Olivi A, DiMeco F. Local delivery of a synthetic endostatin fragment for the treatment of experimental gliomas. Neurosurgery. 57: 1032-40; discussion . PMID 16284573 DOI: 10.1227/01.Neu.0000180059.33665.C1  0.404
2005 Gallia GL, Brem S, Brem H. Local treatment of malignant brain tumors using implantable chemotherapeutic polymers. Journal of the National Comprehensive Cancer Network : Jnccn. 3: 721-8. PMID 16194460 DOI: 10.6004/Jnccn.2005.0042  0.421
2005 Hsu W, Lesniak MS, Tyler B, Brem H. Local delivery of interleukin-2 and adriamycin is synergistic in the treatment of experimental malignant glioma. Journal of Neuro-Oncology. 74: 135-40. PMID 16193383 DOI: 10.1007/S11060-004-6597-8  0.363
2005 Raza SM, Pradilla G, Legnani FG, Thai QA, Olivi A, Weingart JD, Brem H. Local delivery of antineoplastic agents by controlled-release polymers for the treatment of malignant brain tumours. Expert Opinion On Biological Therapy. 5: 477-494. PMID 15934827 DOI: 10.1517/14712598.5.4.477  0.353
2005 Mantha A, Legnani FG, Bagley CA, Gallia GL, Garonzik I, Pradilla G, Amundson E, Tyler BM, Brem H, Gokaslan ZL. A novel rat model for the study of intraosseous metastatic spine cancer. Journal of Neurosurgery. Spine. 2: 303-7. PMID 15796355 DOI: 10.3171/Spi.2005.2.3.0303  0.31
2005 Koenig MA, Geocadin RG, Kulesza P, Olivi A, Brem H. Rhabdoid meningioma occurring in an unrelated resection cavity with leptomeningeal carcinomatosis: Case report Journal of Neurosurgery. 102: 371-375. PMID 15739568 DOI: 10.3171/Jns.2005.102.2.0371  0.336
2005 Chang SM, Parney IF, Huang W, Anderson FA, Asher AL, Bernstein M, Lillehei KO, Brem H, Berger MS, Laws ER. Patterns of care for adults with newly diagnosed malignant glioma. Jama. 293: 557-64. PMID 15687310 DOI: 10.1001/Jama.293.5.557  0.319
2004 Storm PB, Renard VM, Moriarity JL, Tyler B, Wilentz RE, Brem H, Weingart JD. Systemic BCNU enhances the efficacy of local delivery of a topoisomerase I inhibitor against malignant glioma. Cancer Chemotherapy and Pharmacology. 54: 361-7. PMID 15197484 DOI: 10.1007/S00280-004-0800-7  0.311
2004 Lesniak MS, Brem H. Targeted therapy for brain tumours Nature Reviews Drug Discovery. 3: 499-508. PMID 15173839 DOI: 10.1038/Nrd1414  0.344
2004 Samdani AF, Kuchner EB, Rhines L, Adamson DC, Lawson C, Tyler B, Brem H, Dawson VL, Dawson TM. Astroglia induce cytotoxic effects on brain tumors via a nitric oxide-dependent pathway both in vitro and in vivo. Neurosurgery. 54: 1231-7; discussion 1. PMID 15113479 DOI: 10.1227/01.Neu.0000119576.76193.B8  0.385
2004 Kleinberg LR, Weingart J, Burger P, Carson K, Grossman SA, Li K, Olivi A, Wharam MD, Brem H. Clinical Course and Pathologic Findings after Gliadel® and Radiotherapy for Newly Diagnosed Malignant Glioma: Implications for Patient Management Cancer Investigation. 22: 1-9. PMID 15069758 DOI: 10.1081/Cnv-120027575  0.384
2004 Håberg A, Kvistad KA, Unsgård G, Haraldseth O, Weiss N, Brem H, Takakura K, Sawaya R, Langmoen IA. Preoperative Blood Oxygen Level-dependent Functional Magnetic Resonance Imaging in Patients with Primary Brain Tumors: Clinical Application and Outcome Neurosurgery. 54: 902-915. PMID 15046657 DOI: 10.1227/01.Neu.0000114510.05922.F8  0.342
2004 Guerin C, Olivi A, Weingart JD, Lawson HC, Brem H. Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Investigational New Drugs. 22: 27-37. PMID 14707492 DOI: 10.1023/B:Drug.0000006172.65135.3E  0.427
2004 Komotar RJ, Burger PC, Carson BS, Brem H, Olivi A, Goldthwaite PT, Tihan T. Pilocytic and pilomyxoid hypothalamic/chiasmatic astrocytomas. Neurosurgery. 54: 72-9; discussion 79-. PMID 14683543 DOI: 10.1227/01.Neu.0000097266.89676.25  0.331
2003 Legnani FG, Pradilla G, Wang PP, Brem H, Olivi A, DiMeco F. Local delivery of antineoplastic agents using biodegradable polymers for the treatment of malignant brain tumors Expert Review of Neurotherapeutics. 3: 533-546. PMID 19810937 DOI: 10.1586/14737175.3.4.533  0.436
2003 Moses MA, Brem H, Langer R. Advancing the field of drug delivery: Taking aim at cancer Cancer Cell. 4: 337-341. PMID 14667500 DOI: 10.1016/S1535-6108(03)00276-9  0.301
2003 Frazier JL, Wang PP, Case D, Tyler BM, Pradilla G, Weingart JD, Brem H. Local delivery of minocycline and systemic BCNU have synergistic activity in the treatment of intracranial glioma. Journal of Neuro-Oncology. 64: 203-9. PMID 14558595 DOI: 10.1023/A:1025695423097  0.415
2003 Laws ER, Parney IF, Huang W, Anderson F, Morris AM, Asher A, Lillehei KO, Bernstein M, Brem H, Sloan A, Berger MS, Chang S. Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. Journal of Neurosurgery. 99: 467-73. PMID 12959431 DOI: 10.3171/Jns.2003.99.3.0467  0.346
2003 Lesniak MS, Tyler BM, Pardoll DM, Brem H. Gene therapy for experimental brain tumors using a xenogenic cell line engineered to secrete hIL-2. Journal of Neuro-Oncology. 64: 155-60. PMID 12952296 DOI: 10.1007/BF02700030  0.396
2003 Chang SM, Parney IF, McDermott M, Barker FG, Schmidt MH, Huang W, Laws ER, Lillehei KO, Bernstein M, Brem H, Sloan AE, Berger M. Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. Journal of Neurosurgery. 98: 1175-81. PMID 12816260 DOI: 10.3171/Jns.2003.98.6.1175  0.342
2003 Rhines LD, Sampath P, DiMeco F, Lawson HC, Tyler BM, Hanes J, Olivi A, Brem H. Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma. Neurosurgery. 52: 872-9; discussion 87. PMID 12657184 DOI: 10.1227/01.Neu.0000053211.39087.D1  0.359
2003 Sampath P, Amundson E, Wall ME, Tyler BM, Wani MC, Alderson LM, Colvin M, Brem H, Weingart JD. Camptothecin analogs in malignant gliomas: comparative analysis and characterization. Journal of Neurosurgery. 98: 570-7. PMID 12650430 DOI: 10.3171/Jns.2003.98.3.0570  0.376
2002 Lugassy C, Haroun RI, Brem H, Tyler BM, Jones RV, Fernandez PM, Patierno SR, Kleinman HK, Barnhill RL. Pericytic-like angiotropism of glioma and melanoma cells. The American Journal of Dermatopathology. 24: 473-8. PMID 12454598 DOI: 10.1097/00000372-200212000-00003  0.342
2002 DiMeco F, Li KW, Tyler BM, Wolf AS, Brem H, Olivi A. Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats. Journal of Neurosurgery. 97: 1173-8. PMID 12450040 DOI: 10.3171/Jns.2002.97.5.1173  0.402
2002 Wang PP, Frazier J, Brem H. Local drug delivery to the brain Advanced Drug Delivery Reviews. 54: 987-1013. PMID 12384318 DOI: 10.1016/S0169-409X(02)00054-6  0.405
2002 Toung TJ, Tyler B, Brem H, Traystman RJ, Hurn PD, Bhardwaj A. Hypertonic saline ameliorates cerebral edema associated with experimental brain tumor. Journal of Neurosurgical Anesthesiology. 14: 187-93. PMID 12172290 DOI: 10.1097/00008506-200207000-00003  0.379
2002 Haroun RI, Clatterbuck RE, Gibbons MC, Burger PC, Parker R, Fruehauf JP, Brem H. Extreme drug resistance in primary brain tumors: in vitro analysis of 64 resection specimens. Journal of Neuro-Oncology. 58: 115-23. PMID 12164682 DOI: 10.1023/A:1016049111941  0.352
2002 Storm PB, Moriarity JL, Tyler B, Burger PC, Brem H, Weingart J. Polymer delivery of camptothecin against 9L gliosarcoma: release, distribution, and efficacy. Journal of Neuro-Oncology. 56: 209-17. PMID 12061726 DOI: 10.1023/A:1015003232713  0.365
2002 Liu JM, Garonzik IM, Eberhart CG, Sampath P, Brem H. Ectopic recurrence of craniopharyngioma after an interhemispheric transcallosal approach: case report. Neurosurgery. 50: 639-44; discussion 6. PMID 11841735 DOI: 10.1097/00006123-200203000-00041  0.348
2001 Lesniak MS, Langer R, Brem H. Drug delivery to tumors of the central nervous system Current Neurology and Neuroscience Reports. 1: 210-216. PMID 11898520 DOI: 10.1007/S11910-001-0020-Z  0.394
2001 Reavey-Cantwell JF, Haroun RI, Zahurak M, Clatterbuck RE, Parker RJ, Mehta R, Fruehauf JP, Brem H. The prognostic value of tumor markers in patients with glioblastoma multiforme: analysis of 32 patients and review of the literature. Journal of Neuro-Oncology. 55: 195-204. PMID 11859975 DOI: 10.1023/A:1013845004294  0.377
2001 Rothstein JD, Brem H. Excitotoxic destruction facilitates brain tumor growth. Nature Medicine. 7: 994-5. PMID 11533696 DOI: 10.1038/Nm0901-994  0.323
2001 Hanes J, Sills A, Zhao Z, Suh KW, Tyler B, DiMeco F, Brat DJ, Choti MA, Leong KW, Pardoll DM, Brem H. Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. Pharmaceutical Research. 18: 899-906. PMID 11496947 DOI: 10.1023/A:1010963307097  0.38
2001 Brem H, Gabikian P. Biodegradable polymer implants to treat brain tumors. Journal of Controlled Release. 74: 63-67. PMID 11489483 DOI: 10.1016/S0168-3659(01)00311-X  0.427
2001 Sipos EP, Witham TF, Ratan R, Burger PC, Baraban J, Li KW, Piantadosi S, Brem H. L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model. Neurosurgery. 48: 392-400. PMID 11220384 DOI: 10.1097/00006123-200102000-00032  0.414
2000 Lesniak MS, Sampath P, DiMeco F, Viglione MP, Tyler BM, Pardoll DM, Brem H. Comparative analysis of paracrine immunotherapy in experimental brain tumors. Neurosurgical Focus. 9: e4. PMID 16817687 DOI: 10.3171/Foc.2000.9.6.5  0.336
2000 Sipos EP, Brem H. Local Anti-angiogenic Brain Tumor Therapies Journal of Neuro-Oncology. 50: 181-188. PMID 11245278 DOI: 10.1023/A:1006482120049  0.428
2000 Ewend MG, Thompson RC, Anderson R, Sills AK, Staveley-O'Carroll K, Tyler BM, Hanes J, Brat D, Thomas M, Jaffee EM, Pardoll DM, Brem H. Intracranial paracrine interleukin-2 therapy stimulates prolonged antitumor immunity that extends outside the central nervous system. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 438-48. PMID 10916753 DOI: 10.1097/00002371-200007000-00007  0.384
2000 Haroun RI, Brem H. Local drug delivery. Current Opinion in Oncology. 12: 187-193. PMID 10841189 DOI: 10.1097/00001622-200005000-00001  0.318
2000 Haroun RI, Li KW, Carson BS, Brem H. Primary Tumors of the Choroid Plexus Contemporary Neurosurgery. 22: 1-8. DOI: 10.1097/00029679-200002010-00001  0.335
2000 Weingart J, Brem H, Grossman S, Burger P, Wharam M, Kleinberg L. Gliadel followed by radiotherapy for newly diagnosed malignant glioma: Safety results, pathologic findings, and survival International Journal of Radiation Oncology*Biology*Physics. 48: 256. DOI: 10.1016/S0360-3016(00)80310-7  0.323
1999 Suh KW, Piantadosi S, Yazdi HA, Pardoll DM, Brem H, Choti MA. Treatment of liver metastases from colon carcinoma with autologous tumor vaccine expressing granulocyte-macrophage colony-stimulating factor Journal of Surgical Oncology. 72: 218-224. PMID 10589037 DOI: 10.1002/(Sici)1096-9098(199912)72:4<218::Aid-Jso7>3.0.Co;2-N  0.344
1999 Brem H, Lawson HC. The development of new brain tumor therapy utilizing the local and sustained delivery of chemotherapeutic agents from biodegradable polymers Cancer. 86: 197-199. PMID 10421254 DOI: 10.1002/(Sici)1097-0142(19990715)86:2<197::Aid-Cncr2>3.0.Co;2-6  0.384
1998 Sampath P, Brem H. Implantable Slow-Release Chemotherapeutic Polymers for the Treatment of Malignant Brain Tumors. Cancer Control. 5: 130-137. PMID 10761024 DOI: 10.1177/107327489800500204  0.452
1998 Grossman SA, Fisher JD, Piantadosi S, Brem H. The New Approaches to Brain Tumor Therapy (NABTT) CNS Consortium: Organization, Objectives, and Activities. Cancer Control. 5: 107-114. PMID 10761021 DOI: 10.1177/107327489800500201  0.403
1998 Williams JA, Yuan X, Dillehay LE, Shastri VR, Brem H, Williams JR. Synthetic, implantable polymers for local delivery of IUdR to experimental human malignant glioma. International Journal of Radiation Oncology Biology Physics. 42: 631-639. PMID 9806525 DOI: 10.1016/S0360-3016(98)00258-2  0.37
1998 Ewend MG, Sampath P, Williams JA, Tyler BM, Brem H. Local delivery of chemotherapy prolongs survival in experimental brain metastases from breast carcinoma. Neurosurgery. 43: 1185-93. PMID 9802862 DOI: 10.1097/00006123-199811000-00093  0.368
1997 Kleinberg LR, Slick T, Enger C, Grossman S, Brem H, Wharam MD. Short course radiotherapy is an appropriate option for most malignant glioma patients International Journal of Radiation Oncology Biology Physics. 38: 31-36. PMID 9212001 DOI: 10.1016/S0360-3016(97)00222-8  0.353
1997 Sipos EP, Tyler B, Piantadosi S, Burger PC, Brem H. Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors. Cancer Chemotherapy and Pharmacology. 39: 383-9. PMID 9054951 DOI: 10.1007/S002800050588  0.359
1997 Williams JA, Dillehay LE, Tabassi K, Sipos E, Fahlman C, Brem H. Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma Journal of Neuro-Oncology. 32: 181-192. PMID 9049879 DOI: 10.1023/A:1005704913330  0.348
1996 Thompson RC, Pardoll DM, Jaffee EM, Ewend MG, Thomas MC, Tyler BM, Brem H. Systemic and local paracrine cytokine therapies using transduced tumor cells are synergistic in treating intracranial tumors. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 19: 405-13. PMID 9041459 DOI: 10.1097/00002371-199611000-00004  0.355
1996 Olivi A, Ewend MG, Utsuki T, Tyler B, Domb AJ, Brat DJ, Brem H. Interstitial delivery of carboplatin via biodegradable polymers is effective against experimental glioma in the rat. Cancer Chemotherapy and Pharmacology. 39: 90-6. PMID 8995504 DOI: 10.1007/S002800050542  0.38
1996 Ewend MG, Carey LA, Brem H. Treatment of melanoma metastases in the brain Seminars in Surgical Oncology. 12: 429-435. PMID 8914207 DOI: 10.1002/(Sici)1098-2388(199611/12)12:6<429::Aid-Ssu8>3.0.Co;2-C  0.349
1996 Fung LK, Shin M, Tyler B, Brem H, Saltzman WM. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Pharmaceutical Research. 13: 671-82. PMID 8860421 DOI: 10.1023/A:1016083113123  0.316
1996 Utsuki T, Brem H, Pitha J, Loftsson T, Kristmundsdottir T, Tyler BM, Olivi A. Potentiation of anticancer effects of microencapsulated carboplatin by hydroxypropyl α-cyclodextrin Journal of Controlled Release. 40: 251-260. DOI: 10.1016/0168-3659(95)00192-1  0.333
1995 Brem H, Ewend MG, Piantadosi S, Greenhoot J, Burger PC, Sisti M. The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial. Journal of Neuro-Oncology. 26: 111-23. PMID 8787853 DOI: 10.1007/Bf01060217  0.359
1995 Buahin KG, Brem H. Interstitial chemotherapy of experimental brain tumors: comparison of intratumoral injection versus polymeric controlled release. Journal of Neuro-Oncology. 26: 103-110. PMID 8787852 DOI: 10.1007/Bf01060216  0.368
1995 Weingart JD, Sipos EP, Brem H. The role of minocycline in the treatment of intracranial 9L glioma. Journal of Neurosurgery. 82: 635-640. PMID 7897527 DOI: 10.3171/Jns.1995.82.4.0635  0.398
1995 Judy KD, Olivi A, Buahin KG, Domb A, Epstein JI, Colvin OM, Brem H. Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas Journal of Neurosurgery. 82: 481-486. PMID 7861228 DOI: 10.3171/Jns.1995.82.3.0481  0.362
1995 Brem H, Piantadosi S, Burger PC, Walker M, Selker R, Vick NA, Black K, Sisti M, Brem S, Mohr G. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group. Lancet. 345: 1008-12. PMID 7723496 DOI: 10.1016/S0140-6736(95)90755-6  0.389
1995 Weingart JD, Thompson RC, Tyler B, Colvin OM, Brem H. Local delivery of the topoisomerase I inhibitor camptothecin sodium prolongs survival in the rat intracranial 9L gliosarcoma model. International Journal of Cancer. Journal International Du Cancer. 62: 605-9. PMID 7665233 DOI: 10.1002/Ijc.2910620519  0.415
1995 Sipos EP, Brem H. New delivery systems for brain tumor therapy Neurologic Clinics. 13: 813-825. DOI: 10.1016/S0733-8619(18)30019-7  0.394
1994 Brem H, Tamargo RJ, Olivi A, Pinn M, Weingart JD, Wharam M, Epstein JI. Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain Journal of Neurosurgery. 80: 283-290. PMID 8283268 DOI: 10.3171/Jns.1994.80.2.0283  0.352
1994 Olivi A, Brem H. Interstitial Chemotherapy with Sustained-Release Polymer Systems for the Treatment of Malignant Gliomas Recent Results in Cancer Research. 135: 149-154. PMID 8047689 DOI: 10.1007/978-3-642-85039-4_15  0.415
1994 Arosarena O, Guerin C, Brem H, Laterra J. Endothelial differentiation in intracerebral and subcutaneous experimental gliomas. Brain Research. 640: 98-104. PMID 8004469 DOI: 10.1016/0006-8993(94)91861-9  0.359
1994 Cahan MA, Walter KA, Colvin OM, Brem H. Cytotoxicity of taxol in vitro against human and rat malignant brain tumors Cancer Chemotherapy and Pharmacology. 33: 441-444. PMID 7905792 DOI: 10.1007/Bf00686276  0.356
1994 Tapper D, Cahan MA, Brem H. Detection of biological activity in the cerebrospinal fluid of patients with central nervous system tumors. Journal of Neuro-Oncology. 19: 17-23. PMID 7815101 DOI: 10.1007/Bf01051045  0.374
1994 Sipos EP, Tamargo RJ, Weingart JD, Brem H. Inhibition of tumor angiogenesis. Annals of the New York Academy of Sciences. 732: 263-272. PMID 7526758 DOI: 10.1111/J.1749-6632.1994.Tb24741.X  0.356
1994 Tamargo RJ, Langer R, Brem H. Interstitial Drug Delivery to the Central Nervous System Using Controlled Release Polymers: Chemotherapy for Brain Tumors Methods in Neurosciences. 21: 135-149. DOI: 10.1016/B978-0-12-185291-7.50014-X  0.356
1993 Wolff JE, Guerin C, Laterra J, Bressler J, Indurti RR, Brem H, Goldstein GW. Dexamethasone reduces vascular density and plasminogen activator activity in 9L rat brain tumors. Brain Research. 604: 79-85. PMID 7681348 DOI: 10.1016/0006-8993(93)90354-P  0.363
1993 Olivi A, Kim KD, Benedetti L, Epstein JI, Pinn ML, Callegaro L, Brem H. Ocular and brain biocompatibility of polymeric delivery materials prepared from ester derivatives of hyaluronic acid Clinical Materials. 13: 163-168. DOI: 10.1016/0267-6605(93)90104-F  0.322
1992 Phillips SD, Corio RL, Brem H, Mattox D. Ameloblastoma of the Mandible With Intracranial Metastasis: A Case Study Archives of Otolaryngology--Head and Neck Surgery. 118: 861-863. PMID 1642839 DOI: 10.1001/Archotol.1992.01880080083018  0.322
1992 Guerin C, Wolff JE, Laterra J, Drewes LR, Brem H, Goldstein GW. Vascular differentiation and glucose transporter expression in rat gliomas: effects of steroids. Annals of Neurology. 31: 481-7. PMID 1596083 DOI: 10.1002/Ana.410310504  0.309
1992 Griffin CA, Long PP, Carson BS, Brem H. Chromosome abnormalities in low-grade central nervous system tumors Cancer Genetics and Cytogenetics. 60: 67-73. PMID 1591709 DOI: 10.1016/0165-4608(92)90235-Z  0.341
1992 Brem H, Domb A, Lenartz D, Dureza C, Olivi A, Epstein JI. Brain biocompatibility of a biodegradable controlled release polymer consisting of anhydride copolymer of fatty acid dimer and sebacic acid Journal of Controlled Release. 19: 325-329. DOI: 10.1016/0168-3659(92)90087-8  0.326
1992 Buahin KG, Judy KD, Hartke C, Domb AJ, Maniar M, Colvin OM, Brem H. Controlled release of 4-hydroperoxycyclophosphamide from the fatty acid dimer-sebacic acid copolymer Polymers For Advanced Technologies. 3: 311-316. DOI: 10.1002/Pat.1992.220030605  0.335
1991 Tamargo RJ, Sills AK, Reinhard CS, Pinn ML, Long DM, Brem H. Interstitial delivery of dexamethasone in the brain for the reduction of peritumoral edema Journal of Neurosurgery. 74: 956-961. PMID 2033457 DOI: 10.3171/Jns.1991.74.6.0956  0.346
1991 Olivi A, Donehower RC, Mann RB, Brem H. Solitary, isolated metastasis from Ewing's sarcoma to the brain: case report. Surgical Neurology. 35: 239-243. PMID 1996454 DOI: 10.1016/0090-3019(91)90078-N  0.351
1991 Brem H, Mahaley MS, Vick NA, Black KL, Schold SC, Burger PC, Friedman AH, Ciric IS, Eller TW, Cozzens JW. Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. Journal of Neurosurgery. 74: 441-6. PMID 1993909 DOI: 10.3171/Jns.1991.74.3.0441  0.404
1991 Madrid Y, Langer LF, Brem H, Langer R. New directions in the delivery of drugs and other substances to the central nervous system. Advances in Pharmacology (San Diego, Calif.). 22: 299-324. PMID 1958504 DOI: 10.1016/S1054-3589(08)60039-3  0.306
1991 Reinhard CS, Radomsky ML, Saltzman W, Hilton J, Brem H. Polymeric controlled release of dexamethasone in normal rat brain Journal of Controlled Release. 16: 331-339. DOI: 10.1016/0168-3659(91)90010-B  0.311
1990 Brem H. Polymers to treat brain tumours Biomaterials. 11: 699-701. PMID 2090306 DOI: 10.1016/0142-9612(90)90030-T  0.341
1990 Tamargo RJ, Leong KW, Brem H. Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate. Journal of Neuro-Oncology. 9: 131-138. PMID 1702149 DOI: 10.1007/Bf02427833  0.389
1990 Chasin M, Hollenbeck G, Brem H, Grossman SA, Colvin M, Langer R. Interstitial Drug Therapy for Brain Tumors: A Case Study Drug Development and Industrial Pharmacy. 16: 2579-2594. DOI: 10.3109/03639049009058548  0.403
1988 Robey SS, Olson JL, Brem H, Epstein JI. Posterior fossa neuroblastoma occurring in an elderly man Human Pathology. 19: 365-367. PMID 3346012 DOI: 10.1016/S0046-8177(88)80533-1  0.339
1988 Tamargo RJ, Epstein JI, Brem H. Heterotransplantation of malignant human gliomas in neonatal rats Journal of Neurosurgery. 69: 928-933. PMID 3193198 DOI: 10.3171/Jns.1988.69.6.0928  0.302
1975 Brem H, Folkman J. Inhibition of tumor angiogenesis mediated by cartilage. Journal of Experimental Medicine. 141: 427-439. PMID 1113064 DOI: 10.1084/Jem.141.2.427  0.333
Low-probability matches (unlikely to be authored by this person)
1989 Steen RG, Tamargo RJ, Brem H, Glickson JD, Wehrle JP. In vivo 31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: Dose response of spectral changes Magnetic Resonance in Medicine. 11: 258-266. PMID 2779416 DOI: 10.1002/Mrm.1910110214  0.3
2003 Long DM, Gordon T, Bowman H, Etzel A, Burleyson G, Betchen S, Garonzik IM, Brem H. Outcome and cost of craniotomy performed to treat tumors in regional academic referral centers. Neurosurgery. 52: 1056-1065. DOI: 10.1227/01.Neu.0000057745.48813.93  0.299
2009 Gallia GL, Tyler BM, Hann CL, Siu IM, Giranda VL, Vescovi AL, Brem H, Riggins GJ. Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells. Molecular Cancer Therapeutics. 8: 386-93. PMID 19208828 DOI: 10.1158/1535-7163.Mct-08-0680  0.299
1976 Langer R, Brem H, Falterman K, Klein M, Folkman J. Isolations of a cartilage factor that inhibits tumor neovascularization. Science (New York, N.Y.). 193: 70-2. PMID 935859 DOI: 10.1126/Science.935859  0.298
1996 Weingart JD, Brem H. Carmustine implants. Potential in the treatment of brain tumours Cns Drugs. 6: 263-269. DOI: 10.2165/00023210-199606040-00002  0.297
2016 Nailor A, Walker DA, Jacques TS, Warren KE, Brem H, Kearns PR, Greenwood J, Penny JI, Pilkington GJ, Carcaboso AM, Fleischhack G, Macarthur D, Slavc I, Meijer L, Gill S, et al. Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours. Ecancermedicalscience. 10: 630. PMID 27110286 DOI: 10.3332/Ecancer.2016.630  0.297
1996 Dang W, Daviau T, Brem H. Morphological characterization of polyanhydride biodegradable implant Gliadel® during in vitro and in vivo erosion using scanning electron microscopy Pharmaceutical Research. 13: 683-691. PMID 8860422 DOI: 10.1023/A:1016035229961  0.296
1991 Guerin C, Laterra J, Hruban RH, Brem H, Drewes LR, Goldstein GW. The glucose transporter and blood-brain barrier of human brain tumors. Annals of Neurology. 28: 758-65. PMID 2178329 DOI: 10.1002/Ana.410280606  0.296
2011 Chaichana KL, Garzon-Muvdi T, Parker S, Weingart JD, Olivi A, Bennett R, Brem H, Quiñones-Hinojosa A. Supratentorial glioblastoma multiforme: the role of surgical resection versus biopsy among older patients. Annals of Surgical Oncology. 18: 239-45. PMID 20697823 DOI: 10.1245/S10434-010-1242-6  0.295
2009 Almeida JPCd, Petteys RJ, Sciubba DM, Gallia GL, Brem H. Regression of intracranial meningioma following intratumoral hemorrhage Journal of Clinical Neuroscience. 16: 1246-1249. PMID 19560362 DOI: 10.1016/J.Jocn.2008.11.017  0.295
2009 Gathinji M, McGirt MJ, Attenello FJ, Chaichana KL, Than K, Olivi A, Weingart JD, Brem H, Quinones-Hinojosa A. Association of preoperative depression and survival after resection of malignant brain astrocytoma. Surgical Neurology. 71: 299-303, discussion . PMID 18786716 DOI: 10.1016/J.Surneu.2008.07.016  0.295
2016 Patel MA, Kim JE, Theodros D, Tam A, Velarde E, Kochel CM, Francica B, Nirschl TR, Ghasemzadeh A, Mathios D, Harris-Bookman S, Jackson CC, Jackson C, Ye X, Tran PT, ... ... Brem H, et al. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. Journal For Immunotherapy of Cancer. 4: 28. PMID 27190629 DOI: 10.1186/S40425-016-0132-2  0.294
2016 Tyler B, Gullotti D, Mangraviti A, Utsuki T, Brem H. Polylactic acid (PLA) controlled delivery carriers for biomedical applications. Advanced Drug Delivery Reviews. PMID 27426411 DOI: 10.1016/J.Addr.2016.06.018  0.293
1981 Langer R, Brem H, Tapper D. Biocompatibility of polymeric delivery systems for macromolecules. Journal of Biomedical Materials Research. 15: 267-77. PMID 7348718 DOI: 10.1002/Jbm.820150212  0.293
2000 Sampath P, Long DM, Brem H. The Hunterian Neurosurgical Laboratory: the first 100 years of neurosurgical research. Neurosurgery. 46: 184-195. DOI: 10.1093/Neurosurgery/46.1.184  0.292
2018 Santiago G, Wolff A, Huang J, Weingart J, Brem H, Gordon CR. Dural Reconstruction With Autologous Rectus Fascia: A New Technique for Addressing Large-Sized Defects During Cranioplasty. The Journal of Craniofacial Surgery. PMID 30439737 DOI: 10.1097/Scs.0000000000004895  0.29
2010 Grossman R, Mukherjee D, Chaichana KL, Salvatori R, Wand G, Brem H, Chang DC, Quiñones-Hinojosa A. Complications and death among elderly patients undergoing pituitary tumour surgery. Clinical Endocrinology. 73: 361-8. PMID 20455889 DOI: 10.1111/J.1365-2265.2010.03813.X  0.29
2006 Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, Broggi G, Brem H, Olivi A, Dimeco F, Vescovi AL. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature. 444: 761-5. PMID 17151667 DOI: 10.1038/Nature05349  0.29
2016 Sankey EW, Lopez J, Zhong SS, Susarla H, Jusué-Torres I, Liauw J, Huang J, Streiff M, Brem H, Gordon CR. Anticoagulation for Hypercoagulable Patients Associated with Complications after Large Cranioplasty Reconstruction. Plastic and Reconstructive Surgery. 137: 595-607. PMID 26818296 DOI: 10.1097/01.Prs.0000475773.99148.Ba  0.29
2019 Casaos J, Gorelick NL, Huq S, Choi J, Xia Y, Serra R, Felder R, Lott T, Kast RE, Suk I, Brem H, Tyler B, Skuli N. The Use of Ribavirin as an Anticancer Therapeutic: Will It Go Viral? Molecular Cancer Therapeutics. 18: 1185-1194. PMID 31263027 DOI: 10.1158/1535-7163.Mct-18-0666  0.289
1997 Sampath P, Holliday MJ, Brem H, Niparko JK, Long DM. Facial nerve injury in acoustic neuroma (vestibular schwannoma) surgery: etiology and prevention. Journal of Neurosurgery. 87: 60-6. PMID 9202266 DOI: 10.3171/Jns.1997.87.1.0060  0.289
2007 Baird CJ, Hdeib A, Suk I, Francis HW, Holliday MJ, Tamargo RJ, Brem H, Long DM. Reduction of cerebrospinal fluid rhinorrhea after vestibular schwannoma surgery by reconstruction of the drilled porus acusticus with hydroxyapatite bone cement. Journal of Neurosurgery. 107: 347-51. PMID 17695389 DOI: 10.3171/Jns-07/08/0347  0.289
2013 Pendleton C, Olivi A, Brem H, Quiñones-Hinojosa A. Harvey Cushing's early treatment of meningiomas: the untold story. World Neurosurgery. 80: 217-21. PMID 22120300 DOI: 10.1016/J.Wneu.2011.08.021  0.289
2020 Belzberg M, Mahapatra S, Perdomo-Pantoja A, Chavez F, Morrison K, Xiong KT, Gamo NJ, Restaino S, Thakor N, Yazdi Y, Iyer R, Tyler B, Theodore N, Luciano MG, Brem H, et al. Minimally invasive therapeutic ultrasound: Ultrasound-guided ultrasound ablation in neuro-oncology. Ultrasonics. 108: 106210. PMID 32619834 DOI: 10.1016/J.Ultras.2020.106210  0.289
1993 Olivi A, Gilbert MR, Duncan KL, Corden B, Lenartz D, Brem H. Direct delivery of platinum-based antineoplastics to the central nervous system: a toxicity and ultrastructural study Cancer Chemotherapy and Pharmacology. 31: 449-454. PMID 8453683 DOI: 10.1007/Bf00685034  0.288
1996 Williams J, Dillehay L, Tabassi K, Sipos E, Brem H. 2223 Implantable biodegradable polymers for IUdR radiosensitization of human glioma in vivo International Journal of Radiation Oncology Biology Physics. 36: 386. DOI: 10.1016/S0360-3016(97)85796-3  0.288
1995 Williams J, Dillehay LE, Sipos E, Fahlman C, Tabassi K, Williams J, Wharam M, Brem H. 1040 Implantable biodegradable polymers for radiosensitization of human glioma in vivo International Journal of Radiation Oncology Biology Physics. 32: 243. DOI: 10.1016/0360-3016(95)97865-X  0.288
2020 Shay T, Mitchell KA, Belzberg M, Zelko I, Mahapatra S, Qian J, Mendoza L, Huang J, Brem H, Gordon C. Translucent Customized Cranial Implants Made of Clear Polymethylmethacrylate: An Early Outcome Analysis of 55 Consecutive Cranioplasty Cases. Annals of Plastic Surgery. 85: e27-e36. PMID 33170582 DOI: 10.1097/Sap.0000000000002441  0.287
2000 DiMeco F, Rhines LD, Hanes J, Tyler BM, Brat D, Torchiana E, Guarnieri M, Colombo MP, Pardoll DM, Finocchiaro G, Brem H, Olivi A. Paracrine delivery of IL-12 against intracranial 9L gliosarcoma in rats. Journal of Neurosurgery. 92: 419-27. PMID 10701528 DOI: 10.3171/Jns.2000.92.3.0419  0.286
1989 Langer R, Brem H, Langer LF. New directions in CNS drug delivery. Neurobiology of Aging. 10: 642-4; discussion 64. PMID 2812246 DOI: 10.1016/0197-4580(89)90164-4  0.286
2019 Belzberg M, Shalom NB, Yuhanna E, Manbachi A, Tekes A, Huang J, Brem H, Gordon CR. Sonolucent Cranial Implants: Cadaveric Study and Clinical Findings Supporting Diagnostic and Therapeutic Transcranioplasty Ultrasound. The Journal of Craniofacial Surgery. 30: 1456-1461. PMID 31299743 DOI: 10.1097/Scs.0000000000005454  0.285
2020 Garzon-Muvdi T, Maxwell R, Luksik A, Kessler R, Weingart J, Olivi A, Bettegowda C, Tamargo R, Brem H, Lim M. Scalp invasion by atypical or anaplastic meningioma is a risk factor for development of systemic metastasis. World Neurosurgery. PMID 32599198 DOI: 10.1016/J.Wneu.2020.06.148  0.285
2016 Kim JE, Patel MA, Mangraviti A, Kim ES, Theodros D, Velarde E, Liu A, Sankey E, Tam A, Xu H, Mathios D, Jackson CM, Harris-Bookman S, Garzon-Muvdi T, Sheu M, ... ... Brem H, et al. Combination therapy with anti-PD-1, anti-TIM-3, and focal radiation results in regression of murine gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27358487 DOI: 10.1158/1078-0432.Ccr-15-1535  0.285
2001 Conway JE, Chou D, Clatterbuck RE, Brem H, Long DM, Rigamonti D. Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease Neurosurgery. 48: 55-63. PMID 11152361 DOI: 10.1097/00006123-200101000-00009  0.284
1996 Dang W, Daviau T, Ying P, Zhao Y, Nowotnik D, Clow CS, Tyler B, Brem H. Effects of GLIADEL® wafer initial molecular weight on the erosion of wafer and release of BCNU Journal of Controlled Release. 42: 83-92. DOI: 10.1016/0168-3659(96)01371-5  0.284
2020 Mitchell KS, Anderson W, Shay T, Huang J, Luciano M, Suarez JI, Manson P, Brem H, Gordon CR. First-In-Human Experience With Integration of Wireless Intracranial Pressure Monitoring Device Within a Customized Cranial Implant. Operative Neurosurgery (Hagerstown, Md.). PMID 31993644 DOI: 10.1093/Ons/Opz431  0.284
2000 Klink DF, Sampath P, Miller NR, Brem H, Long DM. Long-term Visual Outcome after Nonradical Microsurgery in Patients with Parasellar and Cavernous Sinus Meningiomas Neurosurgery. 47: 24-32. DOI: 10.1097/00006123-200007000-00005  0.282
2015 Chaichana KL, Kone L, Bettegowda C, Weingart JD, Olivi A, Lim M, Quinones-Hinojosa A, Gallia GL, Brem H. Risk of surgical site infection in 401 consecutive patients with glioblastoma with and without carmustine wafer implantation. Neurological Research. 37: 717-26. PMID 25916669 DOI: 10.1179/1743132815Y.0000000042  0.282
2012 Kong S, Sengupta S, Tyler B, Bais AJ, Ma Q, Doucette S, Zhou J, Sahin A, Carter BS, Brem H, Junghans RP, Sampath P. Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor-modified T cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5949-60. PMID 22966020 DOI: 10.1158/1078-0432.Ccr-12-0319  0.282
1977 Brem S, Preis I, Langer R, Brem H, Folkman J, Patz A. Inhibition of neovascularization by an extract derived from vitreous American Journal of Ophthalmology. 84: 323-328. PMID 900228 DOI: 10.1016/0002-9394(77)90672-9  0.282
1998 Perry VL, Watts M, Lesniak M, Burke M, Tyler BM, Brem H. Biodegradable Polymeric Wafers Impregnated with Adriamyc in for the Treatment of Intracranial Neoplasms Neurosurgery. 43: 688-689. DOI: 10.1097/00006123-199809000-00250  0.282
2003 Richards Grayson AC, Choi IS, Tyler BM, Wang PP, Brem H, Cima MJ, Langer R. Multi-pulse drug delivery from a resorbable polymeric microchip device. Nature Materials. 2: 767-72. PMID 14619935 DOI: 10.1038/Nmat998  0.282
1998 Wiranowska M, Ransohoff J, Weingart JD, Phelps C, Phuphanich S, Brem H. Interferon-containing controlled-release polymers for localized cerebral immunotherapy. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 18: 377-85. PMID 9660244 DOI: 10.1089/Jir.1998.18.377  0.281
2016 Sonabend AM, Zacharia BE, Cloney MB, Sonabend A, Showers C, Ebiana V, Nazarian M, Swanson KR, Baldock A, Brem H, Bruce JN, Butler W, Cahill DP, Carter B, Orringer DA, et al. Defining Glioblastoma Resectability Through the Wisdom of the Crowd: A Proof-of-Principle Study. Neurosurgery. PMID 27509070 DOI: 10.1227/Neu.0000000000001374  0.281
2012 Masi BC, Tyler BM, Bow H, Wicks RT, Xue Y, Brem H, Langer R, Cima MJ. Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model. Biomaterials. 33: 5768-75. PMID 22591609 DOI: 10.1016/J.Biomaterials.2012.04.048  0.281
2022 Alomari S, Kedda J, Malla AP, Pacis V, Anastasiadis P, Xu S, McFarland E, Sukhon L, Gallo B, Rincon-Torroella J, Ben-Shalom N, Ames HM, Brem H, Woodworth GF, Tyler B. Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection. Journal of Visualized Experiments : Jove. PMID 35604202 DOI: 10.3791/64048  0.281
2017 Gordon CR, Santiago GF, Huang J, Bergey GK, Liu S, Armand M, Brem H, Anderson WS. First In-Human Experience With Complete Integration of Neuromodulation Device Within a Customized Cranial Implant. Operative Neurosurgery (Hagerstown, Md.). PMID 29029236 DOI: 10.1093/Ons/Opx210  0.279
2015 Berli JU, Thomaier L, Zhong S, Huang J, Quinones A, Lim M, Weingart J, Brem H, Gordon CR. Immediate Single-Stage Cranioplasty Following Calvarial Resection for Benign and Malignant Skull Neoplasms Using Customized Craniofacial Implants. The Journal of Craniofacial Surgery. 26: 1456-62. PMID 26163837 DOI: 10.1097/Scs.0000000000001816  0.278
2021 Serra R, Mangraviti A, Gorelick NL, Shapira-Furman T, Alomari S, Cecia A, Darjee N, Brem H, Rottenberg Y, Domb AJ, Tyler B. Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 170: 179-186. PMID 34968646 DOI: 10.1016/j.ejpb.2021.12.011  0.277
1996 Sipos EP, Tebo SA, Zinreich SJ, Long DM, Brem H. In Vivo Accuracy Testing and Clinical Experience with the ISG Viewing Wand Neurosurgery. 39: 194-204. PMID 8805161 DOI: 10.1097/00006123-199607000-00048  0.277
2016 Tyler BM, Liu A, Sankey EW, Mangraviti A, Barone MA, Brem H. The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 26934692 DOI: 10.1097/Acm.0000000000001136  0.277
2023 Wang F, Huang Q, Su H, Sun M, Wang Z, Chen Z, Zheng M, Chakroun RW, Monroe MK, Chen D, Wang Z, Gorelick N, Serra R, Wang H, Guan Y, ... ... Brem H, et al. Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 120: e2204621120. PMID 37098055 DOI: 10.1073/pnas.2204621120  0.275
2020 Jimenez AE, Khalafallah AM, Huq S, Horowitz MA, Azmeh O, Lam S, Oliveira LAP, Brem H, Mukherjee D. Predictors of Nonroutine Discharge Disposition Among Parasagittal/Parafalcine Meningioma Patients. World Neurosurgery. PMID 32652275 DOI: 10.1016/J.Wneu.2020.06.239  0.275
2018 Garzon-Muvdi T, Theodros D, Luksik AS, Maxwell R, Kim E, Jackson CM, Belcaid Z, Ganguly S, Tyler B, Brem H, Pardoll DM, Lim M. Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma. Oncotarget. 9: 20681-20697. PMID 29755681 DOI: 10.18632/Oncotarget.25061  0.275
2015 Yoshida J, Wicks RT, Zambrano AI, Tyler BM, Javaherian K, Grossman R, Daoud YJ, Gehlbach P, Brem H, Stark WJ. Inhibition of Corneal Neovascularization by Subconjunctival Injection of Fc-Endostatin, a Novel Inhibitor of Angiogenesis. Journal of Ophthalmology. 2015: 137136. PMID 26491546 DOI: 10.1155/2015/137136  0.275
2013 Chaichana KL, Pendleton C, Zaidi H, Olivi A, Weingart JD, Gallia GL, Lim M, Brem H, Quiñones-Hinojosa A. Seizure control for patients undergoing meningioma surgery. World Neurosurgery. 79: 515-24. PMID 22469524 DOI: 10.1016/J.Wneu.2012.02.051  0.274
2019 Smith S, Serra R, Rowlinson J, Gorelick N, Veal G, Shakesheff K, Brem H, Grundy R, Tyler B, Rahman R. SCIDOT-32. NEUROSURGICAL DELIVERY OF THE POLY ADP RIBOSE POLYMERASE-1 INHIBITOR OLAPARIB FROM A THERMO-RESPONSIVE BIODEGRADABLE PASTE POTENTIATES RADIOTHERAPY AND PROLONGS SURVIVAL IN HIGH-GRADE GLIOMA Neuro-Oncology. 21: vi278-vi278. DOI: 10.1093/neuonc/noz175.1168  0.274
2004 Li Y, Shawgo RS, Tyler B, Henderson PT, Vogel JS, Rosenberg A, Storm PB, Langer R, Brem H, Cima MJ. In vivo release from a drug delivery MEMS device. Journal of Controlled Release : Official Journal of the Controlled Release Society. 100: 211-9. PMID 15544869 DOI: 10.1016/J.Jconrel.2004.08.018  0.274
1989 Salibi SS, Nauta HJW, Brem H, Epstein JI, Cho KR. Lipomeningioma: report of three cases and review of the literature. Neurosurgery. 25: 122-126. DOI: 10.1227/00006123-198907000-00024  0.273
2010 Pradilla G, Azzam T, Wang PP, Domb AJ, Brem H. Gene therapy for malignant brain tumors. Expert Review of Neurotherapeutics. 3: 685-701. PMID 19810968 DOI: 10.1586/14737175.3.5.685  0.271
2010 Pradilla G, Azzam T, Wang PP, Domb AJ, Brem H. Gene therapy for malignant brain tumors. Expert Review of Neurotherapeutics. 3: 685-701. PMID 19810968 DOI: 10.1586/14737175.3.5.685  0.271
1995 Walter KA, Tamargo RJ, Olivi A, Burger PC, Brem H. Intratumoral chemotherapy. Neurosurgery. 37: 1128-45. PMID 8584154  0.27
2012 Link TW, Woodworth GF, Chaichana KL, Grossman SA, Mayer RS, Brem H, Weingart JD, Quinones-Hinojosa A. Hyperglycemia is independently associated with post-operative function loss in patients with primary eloquent glioblastoma. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 19: 996-1000. PMID 22595358 DOI: 10.1016/J.Jocn.2011.09.031  0.27
2013 Grossman R, Tyler B, Rudek MA, Kim E, Zadnik P, Khan U, Blakeley JO, Pathak AP, Brem H. Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model. Cancer Chemotherapy and Pharmacology. 72: 93-100. PMID 23649683 DOI: 10.1007/S00280-013-2172-3  0.268
2020 Shay T, Belzberg M, Asemota AO, Mitchell KA, Wolff A, Santiago GF, Huang J, Brem H, Gordon CR. Risk of Complications in Primary Versus Revision-Type Cranioplasty. The Journal of Craniofacial Surgery. PMID 31917710 DOI: 10.1097/Scs.0000000000006134  0.268
2019 Pinheiro L, Perdomo-Pantoja A, Casaos J, Paldor I, Vigilar V, Mangraviti A, Wang Y, Brem H, Tyler B. Captopril as an Adjuvant to Temozolomide Prolongs Survival in a Rat Intracranial Gliosarcoma Model via Downregulation of Matrix Metalloproteinase-2 Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_810  0.266
2019 Jackson C, Choi J, Price C, Bettegowda C, Lim M, Gallia G, Weingart J, Brem H, Mukherjee D. Surg-16. Supratotal Versus Gross Total Resection Of Glioblastoma: A Systematic Review Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.1017  0.266
2014 Starmer HM, Ward BK, Best SR, Gourin CG, Akst LM, Hillel A, Brem H, Francis HW. Patient-perceived long-term communication and swallow function following cerebellopontine angle surgery. The Laryngoscope. 124: 476-80. PMID 23775221 DOI: 10.1002/Lary.24252  0.265
2007 Bookland MJ, Bagley CA, Schwarz J, Burger PC, Brem H. Intracavernous trigeminal ganglion amyloidoma: case report. Neurosurgery. 60: E574; discussion E57. PMID 17327767 DOI: 10.1227/01.Neu.0000255361.32689.B3  0.264
2002 Azzam T, Raskin A, Makovitzki A, Brem H, Vierling P, Lineal M, Domb AJ. Cationic polysaccharides for gene delivery Macromolecules. 35: 9947-9953. DOI: 10.1021/Ma0209592  0.264
2016 Patel MA, Kim JE, Theodros D, Tam A, Velarde E, Kochel CM, Francica B, Nirschl TR, Ghasemzadeh A, Mathios D, Harris-Bookman S, Jackson CC, Jackson C, Ye X, Tran PT, ... ... Brem H, et al. Erratum to: Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. Journal For Immunotherapy of Cancer. 4: 74. PMID 27822377 DOI: 10.1186/S40425-016-0181-6  0.263
2010 Mukherjee D, Zaidi HA, Kosztowski T, Chaichana KL, Brem H, Chang DC, Quiñones-Hinojosa A. Disparities in access to neuro-oncologic care in the United States. Archives of Surgery (Chicago, Ill. : 1960). 145: 247-53. PMID 20231625 DOI: 10.1001/Archsurg.2009.288  0.262
2024 Pant A, Hwa-Lin Bergsneider B, Srivastava S, Kim T, Jain A, Bom S, Shah P, Kannapadi N, Patel K, Choi J, Cho KB, Verma R, Yu-Ju Wu C, Brem H, Tyler B, et al. CCR2 and CCR5 co-inhibition modulates immunosuppressive myeloid milieu in glioma and synergizes with anti-PD-1 therapy. Oncoimmunology. 13: 2338965. PMID 38590799 DOI: 10.1080/2162402X.2024.2338965  0.262
2019 Mathios D, Hwang T, Xia Y, Phallen J, Rui Y, See AP, Maxwell R, Belcaid Z, Casaos J, Burger PC, McDonald KL, Gallia GL, Cope L, Kai M, Brem H, et al. Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types. International Journal of Cancer. PMID 31373686 DOI: 10.1002/Ijc.32587  0.261
1998 Cardinale RM, Dillehay LE, Williams JA, Tabassi K, Brem H, Lee DJ. Effect of interstitial and/or systemic delivery of tirapazamine on the radiosensitivity of human glioblastoma multiforme in nude mice. Radiation Oncology Investigations. 6: 63-70. PMID 9572682 DOI: 10.1002/(SICI)1520-6823(1998)6:2<63::AID-ROI1>3.0.CO;2-F  0.261
2007 Kim GY, Tyler BM, Tupper MM, Karp JM, Langer RS, Brem H, Cima MJ. Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model. Journal of Controlled Release : Official Journal of the Controlled Release Society. 123: 172-8. PMID 17884232 DOI: 10.1016/J.Jconrel.2007.08.003  0.261
2010 Raza SM, Gallia GL, Brem H, Weingart JD, Long DM, Olivi A. Perioperative and long-term outcomes from the management of parasagittal meningiomas invading the superior sagittal sinus. Neurosurgery. 67: 885-93; discussion 8. PMID 20802356 DOI: 10.1227/Neu.0B013E3181Ef2A18  0.26
2023 Jimenez AE, Porras JL, Azad TD, Luksik AS, Jackson C, Bettegowda C, Weingart J, Brem H, Mukherjee D. The mFI-5 and postoperative outcomes in brain tumor patients: A Bayesian approach to quantifying uncertainty. World Neurosurgery. PMID 37419317 DOI: 10.1016/j.wneu.2023.06.130  0.258
1997 Williams JA, Yuan X, Brem H. 2032 Polymers for IUdR radiosensitization of experimental glioblastoma International Journal of Radiation Oncology Biology Physics. 39: 256. DOI: 10.1016/S0360-3016(97)80801-2  0.258
2014 Belcaid Z, Phallen JA, Zeng J, See AP, Mathios D, Gottschalk C, Nicholas S, Ruzevick J, Jackson C, Albesiano E, Durham NM, Tyler B, Wong JW, Brem H, Pardoll DM, et al. Stereotactic Radiation Combined with 41BB Activation and CTLA-4 Blockade Yields Long-Term Survival and a Protective Antigen-Specific Memory Response an a Murine Glioma Model International Journal of Radiation Oncology Biology Physics. 90. DOI: 10.1016/J.Ijrobp.2014.05.158  0.258
2011 Latimer K, Pendleton C, Olivi A, Cohen-Gadol AA, Brem H, Quiñones-Hinojosa A. Harvey Cushing's open and thorough documentation of surgical mishaps at the dawn of neurologic surgery. Archives of Surgery (Chicago, Ill. : 1960). 146: 226-32. PMID 21339437 DOI: 10.1001/Archsurg.2010.319  0.258
1998 Williams J, Enger C, Wharam M, Tsai D, Brem H. Stereotactic radiosurgery for brain metastases : Comparison of lung carcinoma vs. non-lung tumors Journal of Neuro-Oncology. 37: 79-85. PMID 9525842 DOI: 10.1023/A:1005958215384  0.256
1998 Sampath P, Rhines LD, Holliday MJ, Brem H, Long DM. Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Neurosurgical Focus. 5. DOI: 10.3171/Foc.1998.5.3.11  0.255
2015 Kim JE, Patel MA, Mangraviti A, Velarde E, Theodros D, Mathios D, Jackson CM, Tyler B, Ye X, Brem H, Pardoll D, Lim M. 143 The Combination of anti-TIM-3 and anti-PD-1 Checkpoint Inhibitors With Focused Radiation Resulted in a Synergistic Antitumor Immune Response in a Preclinical Glioma Model. Neurosurgery. 62: 212. PMID 26181989 DOI: 10.1227/01.Neu.0000467105.60300.04  0.252
2009 Nixon MK, Chang D, Oyetunji T, Downing S, Mukherjee D, Brem H, Cornwell EE, Quinones-Hinojosa A. Is There a Gender Difference in Mortality Risk Among Traumatic Brain Injury Patients?: 940. Neurosurgery. 65: 414. PMID 28173340 DOI: 10.1227/01.Neu.0000358711.57067.C8  0.252
1992 Guerin C, Laterra J, Masnyk T, Golub LM, Brem H. Selective endothelial growth inhibition by tetracyclines that inhibit collagenase. Biochemical and Biophysical Research Communications. 188: 740-745. PMID 1445318 DOI: 10.1016/0006-291X(92)91118-A  0.252
2019 Gordon CR, Wolff A, Santiago GF, Liebman K, Veznedaroglu E, Vrionis FD, Huang J, Brem H, Luciano M. First-in-Human Experience With Integration of a Hydrocephalus Shunt Device Within a Customized Cranial Implant. Operative Neurosurgery (Hagerstown, Md.). PMID 30753624 DOI: 10.1093/Ons/Opz003  0.252
2004 Basaria S, Westra WH, Brem H, Salvatori R. Metastatic renal cell carcinoma to the pituitary presenting with hyperprolactinemia Journal of Endocrinological Investigation. 27: 471-474. PMID 15279082 DOI: 10.1007/Bf03345294  0.252
2018 Collins ME, Rum S, Wheeler J, Antman K, Brem H, Carrese J, Glennon M, Kahn J, Ohman EM, Jagsi R, Konrath S, Tovino S, Wright S, Sugarman J. Ethical Issues and Recommendations in Grateful Patient Fundraising and Philanthropy. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 30024472 DOI: 10.1097/Acm.0000000000002365  0.251
2019 Serra R, Zhao T, Casaos J, Gorelick NL, Mangraviti A, Olivi A, Brem H, Jackson E, Tyler B. Pdtm-06. Disulfiram-Copper Prolongs Survival And Reduces Stem-Cellness In Pediatric Group 3 Medulloblastoma Through Nuclear Sequestration Of Npl4 Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.782  0.251
2013 Jackson C, Ruzevick J, Brem H, Lim M. Vaccine strategies for glioblastoma: progress and future directions. Immunotherapy. 5: 155-67. PMID 23413907 DOI: 10.2217/Imt.12.155  0.25
2020 Mangraviti A, Volpin F, Cha J, Cunningham SI, Raje K, Brooke MJ, Brem H, Olivi A, Huang J, Tyler BM, Rege A. Intraoperative Laser Speckle Contrast Imaging For Real-Time Visualization of Cerebral Blood Flow in Cerebrovascular Surgery: Results From Pre-Clinical Studies. Scientific Reports. 10: 7614. PMID 32376983 DOI: 10.1038/S41598-020-64492-5  0.249
1991 Nabors MW, Griffin CA, Zehnbauer BA, Hruban RH, Phillips PC, Grossman SA, Brem H, Colvin OM. Multidrug resistance gene (MDR1) expression in human brain tumors Journal of Neurosurgery. 75: 941-946. PMID 1682428 DOI: 10.3171/jns.1991.75.6.0941  0.246
2017 Asemota AO, Ishii M, Brem H, Gallia GL. Comparison of Complications, Trends, and Costs in Endoscopic vs Microscopic Pituitary Surgery: Analysis From a US Health Claims Database. Neurosurgery. 81: 458-472. PMID 28859453 DOI: 10.1093/Neuros/Nyx350  0.246
2022 Pozzi S, Scomparin A, Ben-Shushan D, Yeini E, Ofek P, Nahmad AD, Soffer S, Ionescu A, Ruggiero A, Barzel A, Brem H, Hyde TM, Barshack I, Sinha S, Ruppin E, et al. MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression. Jci Insight. PMID 35980743 DOI: 10.1172/jci.insight.154804  0.244
1998 Hanes J, Tyler BM, Suh KW, DiMeco F, Brat D, Choti M, Pardoll D, Brem H. Synthetic Cytokine Delivery Systems for Cancer Immunotherapy Neurosurgery. 43: 715-716. DOI: 10.1097/00006123-199809000-00361  0.243
1998 Chou D, Sampath P, Brem H. Hemorrhagic vestibular schwannoma: an unusual clinical entity. Case report. Neurosurgical Focus. 5. DOI: 10.3171/Foc.1998.5.3.15  0.243
2010 Recinos VR, Bekelis K, Ziegler SG, Vick D, Hertig S, Tyler BM, Li KW, Kosztowski T, Legnani FG, Brem H, Olivi A. Epirubicin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers. Journal of Neuro-Oncology. 97: 1-10. PMID 19693439 DOI: 10.1007/s11060-009-9984-3  0.241
2023 Ofek P, Yeini E, Arad G, Danilevsky A, Pozzi S, Luna CB, Dangoor SI, Grossman R, Ram Z, Shomron N, Brem H, Hyde TM, Geiger T, Satchi-Fainaro R. Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma. International Journal of Cancer. PMID 37141410 DOI: 10.1002/ijc.34545  0.239
2018 Asemota AO, Ishii M, Brem H, Gallia GL. Costs and Their Predictors in Transsphenoidal Pituitary Surgery. Neurosurgery. PMID 30339258 DOI: 10.1093/Neuros/Nyy441  0.239
2018 Santiago GF, Terner J, Wolff A, Teixeira J, Brem H, Huang J, Gordon CR. Post-Neurosurgical Temporal Deformities: Various Techniques for Correction and Associated Complications. The Journal of Craniofacial Surgery. PMID 29863558 DOI: 10.1097/Scs.0000000000004639  0.237
2016 Nicholas SE, Salvatori R, Rigamonti D, Brem H, Redmond KJ, Quinones-Hinojosa A, Gallia G, Lim M, Kleinberg LR. Deferred Radiation Therapy After Debulking of Nonfunctioning Pituitary Macroadenomas: An Appropriate Option. International Journal of Radiation Oncology, Biology, Physics. 96: E77-E78. PMID 27675461 DOI: 10.1016/J.Ijrobp.2016.06.786  0.237
1989 Brem H, Kader A, Epstein JI, Tamargo RJ, Domb A, Langer R, Leong KW. Biocompatibility of a biodegradable, controlled-release polymer in the rabbit brain. Selective Cancer Therapeutics. 5: 55-65. PMID 2772427 DOI: 10.1089/SCT.1989.5.55  0.237
2023 Parker M, Kalluri A, Materi J, Gujar SK, Schreck K, Mukherjee D, Weingart J, Brem H, Redmond KJ, Lucas CG, Bettegowda C, Rincon-Torroella J. Management and Molecular Characterization of Intraventricular Glioblastoma: A Single-Institution Case Series. International Journal of Molecular Sciences. 24. PMID 37686092 DOI: 10.3390/ijms241713285  0.237
1997 Kleinberg LR, Silverman E, Brem H, Wharam MD. 2073 Outcome of oligodendroglioma treatment in the era of modern neuroimaging International Journal of Radiation Oncology Biology Physics. 39: 277. DOI: 10.1016/S0360-3016(97)80842-5  0.236
2018 Wolff A, Santiago GF, Belzberg M, Huggins C, Lim M, Weingart J, Anderson W, Coon A, Huang J, Brem H, Gordon C. Adult Cranioplasty Reconstruction With Customized Cranial Implants: Preferred Technique, Timing, and Biomaterials. The Journal of Craniofacial Surgery. PMID 29489570 DOI: 10.1097/Scs.0000000000004385  0.235
2017 Brem H, Sankey EW, Liu A, Mangraviti A, Tyler BM. Developing Therapies for Brain Tumors: The Impact of the Johns Hopkins Hunterian Neurosurgical Research Laboratory. Transactions of the American Clinical and Climatological Association. 128: 55-74. PMID 28790487  0.235
2000 Klink DF, Sampath P, Miller NR, Brem H, Long DM. Long-term visual outcome after nonradical microsurgery in patients with parasellar and cavernous sinus meningiomas American Journal of Ophthalmology. 130: 689. PMID 11078866 DOI: 10.1016/S0002-9394(00)00757-1  0.235
1994 Griffin CA, Hruban RH, Long PP, Miller N, Volz P, Carson B, Brem H. Chromosome abnormalities in meningeal neoplasms: Do they correlate with histology? Cancer Genetics and Cytogenetics. 78: 46-52. PMID 7987805 DOI: 10.1016/0165-4608(94)90045-0  0.234
2019 Belzberg M, Shalom NB, Lu A, Yuhanna E, Manbachi A, Tekes A, Huang J, Brem H, Gordon C. Transcranioplasty Ultrasound Through a Sonolucent Cranial Implant Made of Polymethyl Methacrylate: Phantom Study Comparing Ultrasound, Computed Tomography, and Magnetic Resonance Imaging. The Journal of Craniofacial Surgery. PMID 31188246 DOI: 10.1097/Scs.0000000000005651  0.232
1989 Tamargo RJ, Epstein JI, Reinhard CS, Chasin M, Brem H. Brain biocompatibility of a biodegradable, controlled-release polymer in rats. Journal of Biomedical Materials Research. 23: 253-66. PMID 2708412 DOI: 10.1002/JBM.820230209  0.232
2020 Khalafallah AM, Jimenez AE, Shah PP, Brem H, Mukherjee D. Effect of radiation therapy on overall survival following subtotal resection of adult pilocytic astrocytoma. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 81: 340-345. PMID 33222942 DOI: 10.1016/j.jocn.2020.10.020  0.23
2016 Lopez J, Zhong SS, Sankey EW, Swanson EW, Susarla H, Jusue-Torres I, Huang J, Brem H, Auwaerter PG, Gordon CR. Time Interval Reduction for Delayed Implant-Based Cranioplasty Reconstruction in the Setting of Previous Bone Flap Osteomyelitis. Plastic and Reconstructive Surgery. 137: 394e-404e. PMID 26818330 DOI: 10.1097/01.Prs.0000475770.14396.1E  0.228
1993 Schoof DD, Obando JA, Cusack JC, Goedegebuure PS, Brem H, Eberlein TJ. The influence of angiogenesis inhibitor AGM-1470 on immune system status and tumor growth in vitro. International Journal of Cancer. 55: 630-5. PMID 7691763 DOI: 10.1002/IJC.2910550419  0.228
2020 Khalafallah AM, Jimenez AE, Lee RP, Weingart JD, Theodore N, Cohen AR, Tamargo RJ, Huang J, Brem H, Mukherjee D. Impact of COVID-19 on an Academic Neurosurgery Department: The Johns Hopkins Experience. World Neurosurgery. PMID 32461176 DOI: 10.1016/J.Wneu.2020.05.167  0.228
2020 Khalafallah AM, Jimenez AE, Daniels M, Bydon A, Cohen AR, Tamargo RJ, Witham T, Huang J, Brem H, Mukherjee D. Educational Program Rankings Are Independently Associated With Residents' Academic Career Trajectory in Neurological Surgery. Journal of Surgical Education. PMID 32245716 DOI: 10.1016/J.Jsurg.2020.03.004  0.227
1989 Levy AP, Tamargo R, Brem H, Nathans D. An endothelial cell growth factor from the mouse neuroblastoma cell line NB41. Growth Factors (Chur, Switzerland). 2: 9-19. PMID 2483948 DOI: 10.3109/08977198909069077  0.227
1994 Teicher BA, Holden SA, Ara G, Sotomayor EA, Huang ZD, Chen YN, Brem H. Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents. International Journal of Cancer. 57: 920-5. PMID 7515861 DOI: 10.1002/IJC.2910570624  0.226
1992 Grossman SA, Reinhard C, Colvin OM, Chasin M, Brundrett R, Tamargo RJ, Brem H. The intracerebral distribution of BCNU delivered by surgically implanted biodegradable polymers. Journal of Neurosurgery. 76: 640-7. PMID 1545259 DOI: 10.3171/JNS.1992.76.4.0640  0.226
2016 Muvdi TG, Theodros D, Carrera-Haro M, Kim E, Jackson C, Luksik A, Tyler B, Brem H, Padroll D, Lim M. Imst-58. Modulating The Myeloid Compartment To Potentiate Anti-Pd1 Mediated Immunotherapy Against Glioblastoma Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.414  0.225
2016 Chintakunta R, Buaron N, Kahn N, Moriah A, Lifshiz R, Goldbart R, Traitel T, Tyler B, Brem H, Kost J. Synthesis, characterization, and self-assembly with plasmid DNA of a quaternary ammonium derivative of pectic galactan and its fluorescent labeling for bioimaging applications. Carbohydrate Polymers. 150: 308-18. PMID 27312642 DOI: 10.1016/J.Carbpol.2016.05.015  0.224
2018 Wolff AY, Santiago GF, Belzberg M, Manson PN, Huang J, Brem H, Gordon CR. Full-Thickness Skin Grafting for Local Defect Coverage Following Scalp Adjacent Tissue Transfer in the Setting of Cranioplasty. The Journal of Craniofacial Surgery. PMID 30394971 DOI: 10.1097/Scs.0000000000004872  0.224
2018 Gorelick NL, Serra R, Iyer R, Brem H, Tyler B, Luciano MG. 355 Novel Benchtop Model of Hydrocephalus to Study Ventriculo-Peritoneal Shunts Neurosurgery. 65: 141-141. DOI: 10.1093/Neuros/Nyy303.355  0.223
2011 Scott AW, Tyler BM, Masi BC, Upadhyay UM, Patta YR, Grossman R, Basaldella L, Langer RS, Brem H, Cima MJ. Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model. Biomaterials. 32: 2532-9. PMID 21220172 DOI: 10.1016/J.Biomaterials.2010.12.020  0.223
2024 Williams CH, Neitzel LR, Cornell J, Rea S, Mills I, Silver MS, Ahmad JD, Birukov KG, Birukova A, Brem H, Tyler B, Bar EE, Hong CC. GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment. Experimental Hematology & Oncology. 13: 13. PMID 38291540 DOI: 10.1186/s40164-023-00468-1  0.223
2020 Nabors LB, Portnow J, Ahluwalia M, Baehring J, Brem H, Brem S, Butowski N, Campian JL, Clark SW, Fabiano AJ, Forsyth P, Hattangadi-Gluth J, Holdhoff M, Horbinski C, Junck L, et al. Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : Jnccn. 18: 1537-1570. PMID 33152694 DOI: 10.6004/jnccn.2020.0052  0.222
2014 Wicks RT, Huang Y, Zhang K, Zhao M, Tyler BM, Suk I, Hwang L, Ruzevick J, Jallo G, Brem H, Pradilla G, Kang JU. Extravascular optical coherence tomography: evaluation of carotid atherosclerosis and pravastatin therapy. Stroke; a Journal of Cerebral Circulation. 45: 1123-30. PMID 24627118 DOI: 10.1161/Strokeaha.113.002970  0.221
1994 Takamiya Y, Brem H, Ojeifo J, Mineta T, Martuza RL. AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo. Neurosurgery. 34: 869-75; discussion 8. PMID 8052385 DOI: 10.1227/00006123-199405000-00013  0.221
2020 Khalafallah A, Jimenez A, Romo C, Kamson D, Kleinberg L, Weingart J, Brem H, Grossman S, Mukherjee D. NCOG-67. QUANTIFYING THE UTILITY OF A MULTIDISCIPLINARY NEURO-ONCOLOGY TUMOR BOARD Neuro-Oncology. 22: ii144-ii144. DOI: 10.1093/neuonc/noaa215.605  0.22
1991 Weingart JD, Olivi A, Brem H. Supratentorial Low-Grade Astrocytomas in Adults Neurosurgery Quarterly. 1: 141-159. DOI: 10.1097/00013414-199101030-00001  0.22
1993 Zinreich SJ, Tebo SA, Long DM, Brem H, Mattox DE, Loury ME, Kolk CAV, Koch WM, Kennedy DW, Bryan R'. Frameless stereotaxic integration of CT imaging data: accuracy and initial applications. Radiology. 188: 735-742. PMID 8351341 DOI: 10.1148/Radiology.188.3.8351341  0.216
2009 Mukherjee D, Kosztowski T, Zaidi H, Chang D, Jallo GI, Carson BS, Brem H, Quinones-Hinojosa A. Disparities in Referral to Neuro-Oncological Surgery in the United States: 902. Neurosurgery. 65: 401-402. PMID 28175591 DOI: 10.1227/01.Neu.0000358673.43606.Ed  0.214
2003 Hammoud DA, Belden CJ, Ho AC, Dal Pan GJ, Herskovits EH, Hilt DC, Brem H, Pomper MG. The surgical bed after BCNU polymer wafer placement for recurrent glioma: Serial assessment on CT and MR imaging American Journal of Roentgenology. 180: 1469-1475. PMID 12704070 DOI: 10.2214/Ajr.180.5.1801469  0.213
1993 Takamiya Y, Friedlander RM, Brem H, Malick A, Martuza RL. Inhibition of angiogenesis and growth of human nerve-sheath tumors by AGM-1470. Journal of Neurosurgery. 78: 470-6. PMID 8433151 DOI: 10.3171/Jns.1993.78.3.0470  0.213
2021 Gallia GL, Holdhoff M, Brem H, Joshi AD, Hann CL, Bai RY, Staedtke V, Blakeley JO, Sengupta S, Jarrell TC, Wollett J, Szajna K, Helie N, Mattox AK, Ye X, et al. Mebendazole and temozolomide in patients with newly diagnosed high-grade gliomas: results of a phase 1 clinical trial. Neuro-Oncology Advances. 3: vdaa154. PMID 33506200 DOI: 10.1093/noajnl/vdaa154  0.212
2016 Ashayeri K, Jackson E, Huang J, Brem H, Gordon C. Syndrome of the Trephined: A Systematic Review. Neurosurgery. PMID 27489166 DOI: 10.1227/Neu.0000000000001366  0.211
2021 Ding AS, Huq S, Casaos J, Raj D, Morales M, Zhao T, Kim T, Srivastava S, Pant A, Serra R, Gorelick NL, Brem H, Tyler B. Targeting of cyclin-dependent kinases in atypical teratoid rhabdoid tumors with multikinase inhibitor TG02. Journal of Neurosurgery. Pediatrics. 1-10. PMID 34479190 DOI: 10.3171/2021.5.PEDS20920  0.211
2001 White MC, Burke MD, Peleg S, Brem H, Posner GH. Conformationally restricted hybrid analogues of the hormone 1 alpha,25-dihydroxyvitamin D(3): design, synthesis, and biological evaluation. Bioorganic & Medicinal Chemistry. 9: 1691-9. PMID 11425569 DOI: 10.1016/S0968-0896(01)00087-6  0.209
2017 Manbachi A, Kreamer-Tonin K, Walch P, Gamo NJ, Khoshakhlagh P, Zhang YS, Montague C, Acharya S, Logsdon EA, Allen RH, Durr NJ, Luciano MG, Theodore N, Brem H, Yazdi Y. Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur. Annals of Biomedical Engineering. PMID 29019076 DOI: 10.1007/S10439-017-1938-X  0.208
1998 Sampath P, Holliday MJ, Brem H, Niparko JK, Long DM. Facial nerve injury in acoustic neuroma (vestibular schwannoma) surgery: etiology and prevention Neurosurgical Focus. 5. DOI: 10.3171/Foc.1998.5.3.9  0.207
2020 Asemota AO, Ishii M, Brem H, Gallia GL. Geographic Variation in Costs of Transsphenoidal Pituitary Surgery in the United States. World Neurosurgery. PMID 32145414 DOI: 10.1016/J.Wneu.2020.02.145  0.207
2005 Chang S, Parney IF, Berger MS, Anderson FA, Huang W, Asher AL, Bernstein M, Lillehei KO, Brem H, Laws ER. Patterns of Care for Adults With Malignant Glioma—Reply Jama. 293: 2469-2470. DOI: 10.1001/Jama.293.20.2470  0.206
1998 Posner GH, Lee JK, Wang Q, Peleg S, Burke M, Brem H, Dolan P, Kensler TW. Noncalcemic, antiproliferative, transcriptionally active, 24-fluorinated hybrid analogues of the hormone 1alpha, 25-dihydroxyvitamin D3. Synthesis and preliminary biological evaluation. Journal of Medicinal Chemistry. 41: 3008-14. PMID 9685240 DOI: 10.1021/Jm980031T  0.206
2019 Khalafallah AM, Jimenez AE, Tamargo RJ, Witham T, Huang J, Brem H, Mukherjee D. Impact of master's degree attainment upon academic career placement in neurosurgery. Journal of Neurosurgery. 1-9. PMID 31812143 DOI: 10.3171/2019.9.Jns192346  0.206
2015 Sankey EW, Lopez J, Zhong S, Jusue-Torres I, Liauw J, Huang J, Brem H, Gordon C. Abstract 41: Perioperative Anticoagulation Increases the Risk of Complications after Cranioplasty Plastic and Reconstructive Surgery. 135: 36-37. DOI: 10.1097/01.Prs.0000465489.84283.E6  0.205
1992 Griffin CA, Long PP, Brem H, Carson BS, Grossman SA. 22 Chromosome analysis of 50 high grade astrocytomas Cancer Genetics and Cytogenetics. 59: 106. DOI: 10.1016/0165-4608(92)90192-B  0.205
2021 Yeini E, Ofek P, Pozzi S, Albeck N, Ben-Shushan D, Tiram G, Golan S, Kleiner R, Sheinin R, Israeli Dangoor S, Reich-Zeliger S, Grossman R, Ram Z, Brem H, Hyde TM, et al. P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nature Communications. 12: 1912. PMID 33771989 DOI: 10.1038/s41467-021-22186-0  0.204
2004 Lesniak MS, Gabikian P, Tyler BM, Pardoll DM, Brem H. Dexamethasone mediated inhibition of local IL-2 immunotherapy is dose dependent in experimental brain tumors. Journal of Neuro-Oncology. 70: 23-8. PMID 15527103 DOI: 10.1023/B:Neon.0000040821.50347.C5  0.204
1995 O'Reilly MS, Brem H, Folkman J. Treatment of murine hemangioendotheliomas with the angiogenesis inhibitor AGM-1470. Journal of Pediatric Surgery. 30: 325-9; discussion 32. PMID 7738759 DOI: 10.1016/0022-3468(95)90583-9  0.204
2020 Huq S, Khalafallah AM, Brem H, Huang J, Gordon CR, Mukherjee D. Introducing Medical Students to the Burgeoning Field of Neuroplastic Surgery. The Journal of Craniofacial Surgery. PMID 32195837 DOI: 10.1097/Scs.0000000000006351  0.204
2019 Lubelski D, Xiao R, Mukherjee D, Ashley WW, Witham T, Brem H, Huang J, Wolfe SQ. Improving medical student recruitment to neurosurgery. Journal of Neurosurgery. 1-7. PMID 31398709 DOI: 10.3171/2019.5.Jns1987  0.201
1999 Posner GH, Wang Q, Han G, Lee JK, Crawford K, Zand S, Brem H, Peleg S, Dolan P, Kensler TW. Conceptually new sulfone analogues of the hormone 1alpha, 25-dihydroxyvitamin D(3): synthesis and preliminary biological evaluation. Journal of Medicinal Chemistry. 42: 3425-35. PMID 10479276 DOI: 10.1021/Jm990267C  0.2
2021 Medikonda R, Patel K, Jackson C, Saleh L, Srivastava S, Feghali J, Mohan A, Pant A, Jackson CM, Weingart J, Mukherjee D, Bettegowda C, Gallia GL, Brem H, Lim M. The safety and efficacy of dexamethasone in the perioperative management of glioma patients. Journal of Neurosurgery. 1-8. PMID 34560653 DOI: 10.3171/2021.4.JNS204127  0.2
2016 Gordon CR, Murphy RJ, Armand M, Liacouras P, Weingart J, Huang J, Brem H, Lim M. Usefulness of an Osteotomy Template for Skull Tumorectomy and Simultaneous Skull Reconstruction. The Journal of Craniofacial Surgery. PMID 27526253 DOI: 10.1097/Scs.0000000000002999  0.199
1997 Perry JR, DeAngelis LM, Schold SC, Burger PC, Brem H, Brown MT, Curran WJ, Scott CB, Prados MD, Kaplan R, Cairncross JG. Challenges in the design and conduct of phase III brain tumor therapy trials. Neurology. 49: 912-7. PMID 9339667  0.197
1993 Brem H, Folkman J. Analysis of experimental antiangiogenic therapy. Journal of Pediatric Surgery. 28: 445-50; discussion 4. PMID 7682259 DOI: 10.1016/0022-3468(93)90246-H  0.194
2018 Smith S, Gould T, Tyler B, Ritchie A, Veal G, Shakesheff K, Brem H, Grundy R, Rahman R. Overall survival in an orthotopic GBM model is significantly prolonged by neurosurgical delivery of PLGA/PEG interstitial chemotherapy Neuro-Oncology. 20: i6-i6. DOI: 10.1093/NEUONC/NOX237.025  0.194
1983 Friedman JH, Brem H, Mayeux R. Global aphasia in multiple sclerosis. Annals of Neurology. 13: 222-3. PMID 6830195 DOI: 10.1002/Ana.410130234  0.192
1994 Babensee J, Bäckman C, Baker BJ, Banks W, Barker R, Berry M, Biddle PT, Brem H, Bridges RJ, Broadwell RD, Camarata PJ, Carmichael SW, Carvey PM, Chalmers GR, Boni UD, et al. Contributors to Volume 21 Methods in Neurosciences. 21. DOI: 10.1016/B978-0-12-185291-7.50004-7  0.19
1994 Wu MP, Tamada JA, Brem H, Langer R. In vivo versus in vitro degradation of controlled release polymers for intracranial surgical therapy. Journal of Biomedical Materials Research. 28: 387-395. PMID 8077254 DOI: 10.1002/Jbm.820280314  0.19
2020 Serra R, Zhao T, Huq S, Gorelick N, Casaos J, Cecia A, Mangraviti A, Olivi A, Brem H, Jackson EM, Tyler B. EXTH-61. COMBINATION OF DISULFIRAM AND COPPER INDUCES NPL4 AGGREGATION, TARGETS CD133-NESTIN CELLS AND EXTENDS SURVIVAL IN MEDULLOBLASTOMA GROUP 3 MODELS Neuro-Oncology. 22: ii100-ii100. DOI: 10.1093/neuonc/noaa215.415  0.19
2020 Medikonda R, Srivastava S, Kim T, Xia Y, Patel M, Jackson C, Theodros D, Kim J, Kleinberg L, Redmond K, Weingart J, Mukherjee D, Bettegowda C, Gallia G, Brem H, et al. NCOG-05. MANAGEMENT OF BRAIN METASTASIS IN TRIPLE NEGATIVE BREAST CANCER Neuro-Oncology. 22: ii130-ii130. DOI: 10.1093/neuonc/noaa215.544  0.189
2016 Gordon CR, Tamargo RJ, Brem H, Huang J. Discussion of Effect of Reflection of Temporalis Muscle During Cranioplasty With Titanium Mesh After Standard Trauma Craniectomy. The Journal of Craniofacial Surgery. PMID 27054423 DOI: 10.1097/Scs.0000000000002533  0.185
2005 Li Y, Ho Duc HL, Tyler B, Williams T, Tupper M, Langer R, Brem H, Cima MJ. In vivo delivery of BCNU from a MEMS device to a tumor model. Journal of Controlled Release : Official Journal of the Controlled Release Society. 106: 138-45. PMID 16167384 DOI: 10.1016/J.Jconrel.2005.04.009  0.185
2003 Brem H, Amundson E. Preparing Hopkins medical students for a career in academic neurosurgery. Surgery. 134: 414-415. PMID 14555924 DOI: 10.1067/S0039-6060(03)00120-X  0.184
1994 Brem H, Gresser I, Grosfeld J, Folkman J. The combination of antiangiogenic agents to inhibit primary tumor growth and metastasis. Journal of Pediatric Surgery. 28: 1253-7. PMID 7505321 DOI: 10.1016/S0022-3468(05)80308-2  0.178
2021 Huq S, Kannapadi NV, Casaos J, Lott T, Felder R, Serra R, Gorelick NL, Ruiz-Cardozo MA, Ding AS, Cecia A, Medikonda R, Ehresman J, Brem H, Skuli N, Tyler BM. Preclinical efficacy of ribavirin in SHH and group 3 medulloblastoma. Journal of Neurosurgery. Pediatrics. 1-7. PMID 33545678 DOI: 10.3171/2020.8.PEDS20561  0.178
2022 Nair SK, Botros D, Chakravarti S, Mao Y, Wu E, Lu B, Liu S, Elshareif M, Jackson CM, Gallia GL, Bettegowda C, Weingart J, Brem H, Mukherjee D. Predictors of surgical site infection in glioblastoma patients undergoing craniotomy for tumor resection. Journal of Neurosurgery. 1-8. PMID 36208433 DOI: 10.3171/2022.8.JNS212799  0.172
2021 Choi J, Medikonda R, Saleh L, Kim T, Pant A, Srivastava S, Kim YH, Jackson C, Tong L, Routkevitch D, Jackson C, Mathios D, Zhao T, Cho H, Brem H, et al. Combination checkpoint therapy with anti-PD-1 and anti-BTLA results in a synergistic therapeutic effect against murine glioblastoma. Oncoimmunology. 10: 1956142. PMID 34484870 DOI: 10.1080/2162402X.2021.1956142  0.172
2003 Long DM, Gordon T, Bowman H, Etzel A, Burleyson G, Betchen S, Garonzik IM, Brem H. Outcome and Cost of Craniotomy Performed to Treat Tumors in Regional Academic Referral Centers Neurosurgery. 52: 1056-1065. DOI: 10.1093/neurosurgery/52.5.1056  0.171
2003 Long DM, Gordon T, Bowman H, Etzel A, Burleyson G, Betchen S, Garonzik IM, Brem H, Black PM, Berger MS, Holland EC, Gutin PH, Haines SJ, Grossman RG. Outcome and cost of craniotomy performed to treat tumors in regional academic referral centers Neurosurgery. 52: 1056-1065. PMID 12699547  0.171
2003 Li KW, Dang W, Tyler BM, Troiano G, Tihan T, Brem H, Walter KA. Polilactofate microspheres for Paclitaxel delivery to central nervous system malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3441-7. PMID 12960135  0.166
2018 Rahman R, Grundy R, Campbell E, Brem H, Pearl M, Green J, Janowski M, Cohen K, Walczak P, Warren K, Lowis S, Mullen A, Boyd M, Veal G, Hargrave D, et al. EAPH-07. CHILDREN’S BRAIN TUMOUR DRUG DELIVERY CONSORTIUM Neuro-Oncology. 20: i66-i66. DOI: 10.1093/neuonc/noy059.176  0.164
2021 Jimenez AE, Khalafallah AM, Botros D, Horowitz MA, Azmeh O, Lam S, Oliveira LAP, Chakravarti S, Liu S, Wu E, Wei O, Porras JL, Bettegowda C, Tamargo RJ, Brem H, et al. The role of anticoagulation for superior sagittal sinus thrombosis following craniotomy for resection of parasagittal/parafalcine meningiomas. Journal of Neuro-Oncology. PMID 34855096 DOI: 10.1007/s11060-021-03916-2  0.157
2021 Serra R, Zhao T, Huq S, Gorelick NL, Casaos J, Cecia A, Mangraviti A, Eberhart C, Bai R, Olivi A, Brem H, Jackson EM, Tyler B. Disulfiram and copper combination therapy targets NPL4, cancer stem cells and extends survival in a medulloblastoma model. Plos One. 16: e0251957. PMID 34731160 DOI: 10.1371/journal.pone.0251957  0.151
2022 Rincon-Torroella J, Rakovec M, Khalafallah AM, Liu A, Bettegowda A, Kut C, Rodriguez FJ, Weingart J, Luciano M, Olivi A, Jallo GI, Brem H, Mukherjee D, Lim M, Bettegowda C. Clinical features and surgical outcomes of intracranial and spinal cord subependymomas. Journal of Neurosurgery. 1-12. PMID 35148513 DOI: 10.3171/2021.12.JNS211643  0.15
2022 Belzberg M, Mitchell KA, Ben-Shalom N, Asemota AO, Wolff AY, Santiago GF, Shay T, Huang J, Manson PN, Brem H, Gordon CR. Cranioplasty Outcomes From 500 Consecutive Neuroplastic Surgery Patients. The Journal of Craniofacial Surgery. PMID 35245275 DOI: 10.1097/SCS.0000000000008546  0.148
2021 Pinheiro L, Perdomo-Pantoja A, Casaos J, Huq S, Paldor I, Vigilar V, Mangraviti A, Wang Y, Witham TF, Brem H, Tyler B. Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model. Clinical Neurology and Neurosurgery. 207: 106771. PMID 34198223 DOI: 10.1016/j.clineuro.2021.106771  0.147
2021 Medikonda R, Srivastava S, Kim T, Xia Y, Kim J, Jackson C, Weingart J, Mukherjee D, Bettegowda C, Gallia G, Brem H, Redmond K, Stearns V, Kleinberg L, Lim M. Development of new brain metastases in triple negative breast cancer. Journal of Neuro-Oncology. PMID 33512631 DOI: 10.1007/s11060-021-03702-0  0.146
2019 Belzberg M, Shalom NB, Yuhanna E, Manbachi A, Tekes A, Huang J, Brem H, Gordon CR. Sonolucent Cranial Implants: Cadaveric Study and Clinical Findings Supporting Diagnostic and Therapeutic Transcranioplasty Ultrasound. The Journal of Craniofacial Surgery. PMID 30939550 DOI: 10.1097/SCS.0000000000005454  0.145
2021 Jimenez AE, Shah PP, Khalafallah AM, Huq S, Porras JL, Jackson CM, Gallia G, Bettegowda C, Weingart J, Suarez JI, Brem H, Mukherjee D. Patient-Specific Factors Drive Intensive Care Unit and Total Hospital Length of Stay in Operative Brain Tumor Patients. World Neurosurgery. PMID 34217859 DOI: 10.1016/j.wneu.2021.06.114  0.144
2022 Botros D, Khalafallah AM, Huq S, Dux H, Oliveira LAP, Pellegrino R, Jackson C, Gallia GL, Bettegowda C, Lim M, Weingart J, Brem H, Mukherjee D. Predictors and Impact of Postoperative 30-Day Readmission in Glioblastoma. Neurosurgery. PMID 35876679 DOI: 10.1227/neu.0000000000002063  0.144
2021 Medikonda R, Choi J, Pant A, Saleh L, Routkevitch D, Tong L, Belcaid Z, Kim YH, Jackson CM, Jackson C, Mathios D, Xia Y, Shah PP, Patel K, Kim T, ... ... Brem H, et al. Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma. Journal of Neurosurgery. 1-10. PMID 34388730 DOI: 10.3171/2021.1.JNS202482  0.143
2022 Ben-Shalom N, Asemota AO, Belzberg M, Harnof S, Huang J, Lim M, Brem H, Gordon C. Cranioplasty With Customized Craniofacial Implants and Intraoperative Resizing for Single-Stage Reconstruction Following Oncologic Resection of Skull Neoplasms. The Journal of Craniofacial Surgery. PMID 35288504 DOI: 10.1097/SCS.0000000000008541  0.143
2020 Medikonda R, Patel K, Saleh L, Srivastava S, Jackson C, Mohan A, Weingart J, Bettegowda C, Gallia G, Brem H, Lim M. NCOG-32. THE SAFETY AND EFFICACY OF DEXAMETHASONE IN THE MANAGEMENT OF GLIOMA PATIENTS Neuro-Oncology. 22: ii136-ii136. DOI: 10.1093/neuonc/noaa215.570  0.142
2020 Bechtold R, Tselepidakis N, Garlow B, Glaister S, Zhu W, Liu R, Szewc A, Tandon A, Buono Z, Pitingolo J, Madalo C, Ferrara I, Shale C, Benassi T, Belzberg M, ... ... Brem H, et al. Minimizing cotton retention in neurosurgical procedures: which imaging modality can help? Proceedings of Spie--the International Society For Optical Engineering. 11317. PMID 35350430 DOI: 10.1117/12.2548847  0.142
2020 Medikonda R, Patel K, Saleh L, Srivastava S, Jackson C, Mohan A, Shah P, Weingart J, Bettegowda C, Gallia G, Brem H, Lim M. NCOG-25. EFFICACY OF ANTICONVULSANT THERAPY IN GLIOMA PATIENTS Neuro-Oncology. 22: ii134-ii134. DOI: 10.1093/neuonc/noaa215.563  0.14
2001 Kaminski JM, Movsas B, King E, Yang C, Kronz JD, Alli PM, Williams J, Brem H. Metastatic meningioma to the lung with multiple pleural metastases American Journal of Clinical Oncology: Cancer Clinical Trials. 24: 579-582. PMID 11801758 DOI: 10.1097/00000421-200112000-00010  0.135
2021 Jimenez AE, Chakravarti S, Liu S, Wu E, Wei O, Shah PP, Nair S, Gendreau JL, Porras JL, Azad TD, Jackson CM, Gallia G, Bettegowda C, Weingart J, Brem H, et al. Predicting High-Value Care Outcomes Following Surgery for Non-Skull Base Meningiomas. World Neurosurgery. PMID 34896348 DOI: 10.1016/j.wneu.2021.12.010  0.131
2020 Bechtold R, Garlow B, Liu R, Tandon A, Szewc A, Zhu W, Musmanno O, Gorelick N, Suk I, Huang J, Brem H, Manbachi A, Coles G. Minimizing cotton ball retention in neurological procedures. 2020 Design of Medical Devices Conference (Dmd 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.). 2020. PMID 35253016 DOI: 10.1115/dmd2020-9042  0.126
2024 Jimenez AE, Chakravarti S, Liu J, Kazemi F, Jackson C, Gallia G, Bettegowda C, Weingart J, Brem H, Mukherjee D. The Hospital Frailty Risk Score independently predicts postoperative outcomes in glioblastoma patients. World Neurosurgery. PMID 38211815 DOI: 10.1016/j.wneu.2024.01.021  0.125
1991 Dugan JD, Lawton MT, Glaser B, Brem H. A new technique for explantation and in vitro cultivation of chicken embryos. The Anatomical Record. 229: 125-8. PMID 1996778 DOI: 10.1002/AR.1092290114  0.123
2015 Patel M, Kim J, Theodros D, Jackson C, Tam A, Velarde E, Tyler B, Ye X, Brem H, Selby M, Drake C, Pardoll D, Lim M. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P194  0.117
2018 Ehresman J, Garzon-Muvdi T, Rogers D, Lim M, Gallia G, Weingart J, Brem H, Bettegowda C, Chaichana K. The Relevance of Simpson Grade Resections in the Modern Neurosurgical Treatment of World Health Organization Grades 1, 2, and 3 Meningiomas Journal of Neurological Surgery Part B: Skull Base. 79: S1-S188. DOI: 10.1055/s-0038-1633750  0.114
2021 Mahapatra S, Balamurugan M, Chung K, Kuppoor V, Curry E, Aghabaglau F, Kaovasia TP, Acord M, Ainechi A, Kim JH, Tshey Y, Ghinda CD, Son JK, Pustavoitau A, Tyler B, ... ... Brem H, et al. Automatic detection of cotton balls during brain surgery: Where deep learning meets ultrasound imaging to tackle foreign objects. Proceedings of Spie--the International Society For Optical Engineering. 11602. PMID 35233128 DOI: 10.1117/12.2580887  0.114
2024 Parker M, Kazemi F, Ahmed AK, Kuo CC, Nair SK, Rincon-Torroella J, Jackson C, Gallia G, Bettegowda C, Weingart J, Brem H, Mukherjee D. Exploring the impact of primary care utilization and health information exchange upon treatment patterns and clinical outcomes of glioblastoma patients. Journal of Neuro-Oncology. PMID 38662150 DOI: 10.1007/s11060-024-04677-4  0.111
2022 Abramson HG, Curry EJ, Mess G, Thombre R, Kempski-Leadingham KM, Mistry S, Somanathan S, Roy L, Abu-Bonsrah N, Coles G, Doloff JC, Brem H, Theodore N, Huang J, Manbachi A. Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing. Frontiers in Surgery. 9: 1040066. PMID 36532130 DOI: 10.3389/fsurg.2022.1040066  0.108
2005 Quinn JA, Desjardins A, Weingart J, Brem H, Dolan ME, Delaney SM, Vredenburgh J, Rich J, Friedman AH, Reardon DA, Sampson JH, Pegg AE, Moschel RC, Birch R, McLendon RE, et al. Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7178-87. PMID 16192602 DOI: 10.1200/Jco.2005.06.502  0.108
2022 Azad TD, Shah PP, Kannapadi NV, Rincon-Torroella J, Xia Y, Bernhardt LJ, Hansen LJ, Materi J, Raj D, Jackson CM, Mukherjee D, Gallia GL, Weingart J, Suarez JI, Brem H, et al. Reexamining the Role of Postoperative ICU Admission for Patients Undergoing Elective Craniotomy: A Systematic Review. Critical Care Medicine. PMID 35686911 DOI: 10.1097/CCM.0000000000005588  0.097
2012 Zeng J, See A, Phallen J, Belcaid Z, Durham N, Meyer C, Pradilla G, Ford E, Wong J, Hammers H, Tyler B, Brem H, Tran P, Pardoll D, Lim M. 90 COMBINING ANTI-PD-1 IMMUNOTHERAPY WITH STEREOTACTIC RADIOSURGERY IN A MOUSE ORTHOTOPIC GLIOBLASTOMA MODEL Radiotherapy and Oncology. 102: S34. DOI: 10.1016/S0167-8140(12)70066-X  0.097
2002 Freitag SK, Miller NR, Brem H. Recurrent ectopic craniopharyngioma. British Journal of Neurosurgery. 15: 511-3. PMID 11814004 DOI: 10.1080/02688690120097723  0.095
2012 Chou D, Sampath P, Brem H. Hemorrhagic vestibular schwannoma: an unusual clinical entity. Case report. Neurosurgical Focus. 5: e9. PMID 17112224 DOI: 10.3171/foc.1998.5.5.10  0.095
2019 Santiago G, Huang J, Bergey G, Liu S, Armand M, Brem H, Anderson W, Gordon C. S1-13 18-MONTH OUTCOME REPORT FOR FIRST-IN-HUMAN NEUROMODULATION DEVICE INTEGRATED WITHIN CUSTOMIZED CRANIAL IMPLANT Plastic and Reconstructive Surgery - Global Open. 7: 17-18. DOI: 10.1097/01.gox.0000582808.24323.d3  0.092
2022 Lee RP, Meggyesy M, Ahn J, Ritter C, Suk I, Machnitz AJ, Huang J, Gordon C, Brem H, Luciano M. First Experience With Postoperative Transcranial Ultrasound Through Sonolucent Burr Hole Covers in Adult Hydrocephalus Patients. Neurosurgery. 92: 382-390. PMID 36637272 DOI: 10.1227/neu.0000000000002221  0.092
1991 Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, Folkman J. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature. 348: 555-7. PMID 1701033 DOI: 10.1038/348555A0  0.09
1994 Takamiya Y, Brem H, Ojeifo J, Mineta T, Martuza RL. AGM-1470 Inhibits the Growth of Human Glioblastoma Cells in Vitro and in Vivo Neurosurgery. 34: 869-875. DOI: 10.1097/00006123-199405000-00013  0.088
2020 Jackson CM, Choi J, Routkevitch D, Pant A, Saleh L, Ye X, Caplan JM, Huang J, McDougall CG, Pardoll DM, Brem H, Tamargo RJ, Lim M. PD-1+ Monocytes Mediate Cerebral Vasospasm Following Subarachnoid Hemorrhage. Neurosurgery. PMID 33370819 DOI: 10.1093/neuros/nyaa495  0.087
2022 Azad TD, Rodriguez E, Raj D, Xia Y, Materi J, Rincon-Torroella J, Fernando GL, Suarez JI, Tamargo RJ, Brem H, Haut ER, Bettegowda C. Patient Safety Indicator 04 Does Not Consistently Identify Failure to Rescue in the Neurosurgical Population. Neurosurgery. PMID 36399684 DOI: 10.1227/neu.0000000000002204  0.086
1991 Snyder D, Williams M, Brem H, Eleff S, Norris K, Hanley D. INFLUENCE OF TISSUE LAYERS ON NONINVASIVE MEASUREMENT OF BRAIN OXYGENATION WITH NEAR-INFRARED SPECTROSCOPY Anesthesiology. 75: A208-A208. DOI: 10.1097/00000542-199109001-00208  0.081
2023 Lee RP, Antar A, Guryildirim M, Brem H, Luciano M, Huang J. Establishing proof of concept for sonolucent cranioplasty and point of care ultrasound imaging after posterior fossa decompression for Chiari malformation. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 113: 38-44. PMID 37167829 DOI: 10.1016/j.jocn.2023.05.002  0.078
2021 Mitchell KS, Zelko I, Shay T, Horen S, Williams A, Luciano M, Huang J, Brem H, Gordon CR. The Impact of Hydrocephalus Shunt Devices on Quality of Life. The Journal of Craniofacial Surgery. 32: 1746-1750. PMID 34319679 DOI: 10.1097/SCS.0000000000007579  0.076
2020 Mitchell KS, Shay T, Huang J, Brem H, Manson P, Gordon CR. The Neuroplastic Surgery Fellowship Experience: Where Tradition Meets Innovation. The Journal of Craniofacial Surgery. PMID 33136790 DOI: 10.1097/SCS.0000000000007201  0.07
2007 Michaels RK, Makary MA, Dahab Y, Frassica FJ, Heitmiller E, Rowen LC, Crotreau R, Brem H, Pronovost PJ. Achieving the National Quality Forum's "Never Events": prevention of wrong site, wrong procedure, and wrong patient operations. Annals of Surgery. 245: 526-32. PMID 17414599 DOI: 10.1097/01.Sla.0000251573.52463.D2  0.07
2005 Brem SS, Bierman PJ, Black P, Blumenthal DT, Brem H, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Fine HA, Friedman A, Glass J, Grossman SA, Heimberger AB, Junck L, et al. Central nervous system cancers: Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : Jnccn. 3: 644-90. PMID 16194456  0.065
2008 Brem SS, Bierman PJ, Black P, Brem H, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Glass J, Grossman SA, Heimberger AB, Junck L, Linette GP, et al. Central nervous system cancers. Journal of the National Comprehensive Cancer Network : Jnccn. 6: 456-504. PMID 18492461  0.061
2017 Gordon CR, Huang J, Brem H. Neuroplastic Surgery. The Journal of Craniofacial Surgery. PMID 29077688 DOI: 10.1097/SCS.0000000000004063  0.06
2021 Buaron N, Mangraviti A, Volpin F, Liu A, Pedone M, Sankey E, Aranovich D, Adar I, Rodriguez FJ, Nyska A, Goldbart R, Traitel T, Brem H, Tyler B, Kost J. Pectic Galactan Polysaccharide‐Based Gene Delivery System for Targeting Neuroinflammation Advanced Functional Materials. 31: 2100643. DOI: 10.1002/ADFM.202100643  0.059
2013 Kudlak K, Demuro JP, Hanna AF, Brem H. Acute lung injury following the use of granulocyte-macrophage colony-stimulating factor. International Journal of Critical Illness and Injury Science. 3: 279-81. PMID 24459628 DOI: 10.4103/2229-5151.124168  0.058
2021 Asemota AO, Ishii M, Brem H, Gallia GL. Letter: Commentary: Costs and Their Predictors in Transsphenoidal Pituitary Surgery. Neurosurgery. PMID 33582772 DOI: 10.1093/neuros/nyab027  0.055
1993 Brem H, Klagsbrun M. The role of fibroblast growth factors and related oncogenes in tumor growth. Cancer Treatment and Research. 63: 211-231. PMID 1284026 DOI: 10.1007/978-1-4615-3088-6_10  0.044
2020 Ghali MGZ, Ghali GZ, Lima A, McDermott M, Glover E, Voglis S, Humphrey J, König MSS, Brem H, Uhlén P, Spetzler RF, Yasargil MG. Mechanisms underlying the generation of autonomorespiratory coupling amongst the respiratory central pattern generator, sympathetic oscillators, and cardiovagal premotoneurons. Journal of Integrative Neuroscience. 19: 521-560. PMID 33070533 DOI: 10.31083/j.jin.2020.03.0196  0.04
2022 Alomari S, Lubelski D, Feghali J, Brem H, Witham T, Huang J. Impact of virtual vs. in-person interviews among neurosurgery residency applicants. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 101: 63-66. PMID 35561432 DOI: 10.1016/j.jocn.2022.05.005  0.04
2021 Yang W, Rincon-Torroella J, Feghali J, Khalafallah AM, Ishida W, Perdomo-Pantoja A, Quiñones-Hinojosa A, Lim M, Gallia GL, Riggins GJ, Anderson WS, Lo SL, Rigamonti D, Tamargo RJ, Witham TF, ... ... Brem H, et al. Impact of international research fellows in neurosurgery: results from a single academic center. Journal of Neurosurgery. 1-11. PMID 34298505 DOI: 10.3171/2021.1.JNS203824  0.039
2022 Feghali J, Antar A, Wicks EE, Sattari SA, Li S, Witham TF, Brem H, Huang J. Recruitment of women in neurosurgery: a 7-year quantitative analysis. Journal of Neurosurgery. 1-10. PMID 35901758 DOI: 10.3171/2022.4.JNS22410  0.039
2006 Peppa M, Brem H, Cai W, Zhang JG, Basgen J, Li Z, Vlassara H, Uribarri J. Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711). American Journal of Nephrology. 26: 430-6. PMID 16974073 DOI: 10.1159/000095786  0.037
2023 Khalafallah AM, Chakravarti S, Cicalese KV, Porras JL, Kuo CC, Jimenez AE, Brem H, Witham T, Huang J, Mukherjee D. An asynchronous web-based intervention for neurosurgery residents to improve education on cost-effective care. Clinical Neurology and Neurosurgery. 232: 107887. PMID 37473488 DOI: 10.1016/j.clineuro.2023.107887  0.036
1989 Verrier ED, Crombleholme TM, Sauer L, Longaker M, Langer JC, Flake AW, Dae M, Brem H, Harrison MR. Neonatal model of heterotopic heart transplantation in pigs The Journal of Thoracic and Cardiovascular Surgery. 98: 127-136. DOI: 10.1016/S0022-5223(19)34468-X  0.035
2021 Antar A, Feghali J, Wicks EE, Sattari SA, Li S, Witham TF, Brem H, Huang J. Which medical schools produce the most neurosurgery residents? An analysis of the 2014-2020 cohort. Journal of Neurosurgery. 1-13. PMID 34826816 DOI: 10.3171/2021.7.JNS211530  0.034
2010 POSNER GH, LEE JK, WANG Q, PELEG S, BURKE M, BREM H, DOLAN P, KENSLER TW. ChemInform Abstract: Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3. Synthesis and Preliminary Biological Evaluation. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199848069  0.034
2019 Gordon C, Wolff A, Santiago G, Liebman K, Veznedaroglu E, Vrionis F, Belzberg M, Benshalom N, Huang J, Brem H, Luciano M. S1-12 A REPORT OF THE WORLD’S FIRST SEVEN CASES Plastic and Reconstructive Surgery - Global Open. 7: 17. DOI: 10.1097/01.GOX.0000582804.47194.5a  0.033
2003 Peppa M, Brem H, Ehrlich P, Zhang JG, Cai W, Li Z, Croitoru A, Thung S, Vlassara H. Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice. Diabetes. 52: 2805-13. PMID 14578300 DOI: 10.2337/diabetes.52.11.2805  0.029
2021 Khalafallah AM, Jimenez AE, Camp S, Horowitz MA, Chiu I, Ryu D, Charewycz N, Vera L, Bhoopalam M, Feghali J, Sharma M, Lubelski D, Cohen AR, Tamargo RJ, Witham T, ... ... Brem H, et al. Predictors of Academic Neurosurgical Career Trajectory among International Medical Graduates Training Within the United States. Neurosurgery. PMID 34114014 DOI: 10.1093/neuros/nyab194  0.027
2021 Ghali MGZ, Ghali GZ, Lima A, McDermott M, Glover E, Voglis S, Humphrey J, König MSS, Brem H, Uhlén P, Spetzler RF, Yasargil MG. Retraction: Ghali MGZ, . Mechanisms underlying the generation of autonomorespiratory coupling amongst the respiratory central pattern generator, sympathetic oscillators, and cardiovagal premotoneurons. Journal of Integrative Neuroscience. 2020; 19: 521-560. Journal of Integrative Neuroscience. 20: 527. PMID 34258955 DOI: 10.31083/j.jin.2020.03.0196R  0.025
2022 Antar A, Feghali J, Yang W, Wicks EE, Sattari SA, Li S, Witham TF, Brem H, Huang J. Home Program Matching in Neurosurgical Residency Programs: A 7-Year Study. World Neurosurgery. PMID 35595044 DOI: 10.1016/j.wneu.2022.05.040  0.023
1974 Brem H, Coward JE, Rosenkranz HS. 1,2-dibromoethane--effect on the metabolism and ultrastructure of Escherichia coli. Biochemical Pharmacology. 23: 2345-7. PMID 4605455 DOI: 10.1016/0006-2952(74)90569-3  0.014
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