Junko Kurokawa - Publications

Affiliations: 
Tokyo Medical and Dental University, Bunkyō-ku, Tōkyō-to, Japan 

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kernik DC, Yang PC, Kurokawa J, Wu JC, Clancy CE. A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants. Plos Computational Biology. 16: e1008109. PMID 32797034 DOI: 10.1371/Journal.Pcbi.1008109  0.334
2019 Kodama M, Furutani K, Kimura R, Ando T, Sakamoto K, Nagamori S, Ashihara T, Kurachi Y, Sekino Y, Furukawa T, Kanda Y, Kurokawa J. Systematic expression analysis of genes related to generation of action potentials in human iPS cell-derived cardiomyocytes. Journal of Pharmacological Sciences. PMID 31279582 DOI: 10.1016/J.Jphs.2019.06.006  0.347
2019 Kernik DC, Morotti S, Wu H, Garg P, Duff HJ, Kurokawa J, Jalife J, Wu JC, Grandi E, Clancy CE. A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources. The Journal of Physiology. PMID 31278749 DOI: 10.1113/Jp277724  0.375
2019 Sakamoto K, Kurokawa J. Involvement of sex hormonal regulation of K channels in electrophysiological and contractile functions of muscle tissues. Journal of Pharmacological Sciences. PMID 30962088 DOI: 10.1016/J.Jphs.2019.02.009  0.434
2018 Okada JI, Yoshinaga T, Kurokawa J, Washio T, Furukawa T, Sawada K, Sugiura S, Hisada T. Arrhythmic hazard map for a 3D whole-ventricles model under multiple ion channel block. British Journal of Pharmacology. PMID 29745425 DOI: 10.1111/Bph.14357  0.369
2017 Miyamoto K, Akiyama M, Tamura F, Isomi M, Yamakawa H, Sadahiro T, Muraoka N, Kojima H, Haginiwa S, Kurotsu S, Tani H, Wang L, Qian L, Inoue M, Ide Y, ... Kurokawa J, et al. Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction. Cell Stem Cell. PMID 29276141 DOI: 10.1016/J.Stem.2017.11.010  0.342
2017 Li M, Kanda Y, Ashihara T, Sasano T, Nakai Y, Kodama M, Hayashi E, Sekino Y, Furukawa T, Kurokawa J. Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs. Journal of Pharmacological Sciences. PMID 28615142 DOI: 10.1016/J.Jphs.2017.05.004  0.46
2017 Yang PC, Perissinotti LL, López-Redondo F, Wang Y, DeMarco KR, Jeng MT, Vorobyov I, Harvey RD, Kurokawa J, Noskov SY, Clancy CE. A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias. The Journal of Physiology. PMID 28516454 DOI: 10.1113/Jp273142  0.694
2017 Kodama M, Kurokawa J. A risk assessment of a common drug using xenograft model. Annals of Translational Medicine. 5: 88. PMID 28275633 DOI: 10.21037/Atm.2017.01.59  0.302
2016 Okata S, Yuasa S, Suzuki T, Ito S, Makita N, Yoshida T, Li M, Kurokawa J, Seki T, Egashira T, Aizawa Y, Kodaira M, Motoda C, Yozu G, Shimojima M, et al. Embryonic type Na(+) channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome. Scientific Reports. 6: 34198. PMID 27677334 DOI: 10.1038/Srep34198  0.399
2016 Kurokawa J, Kodama M, Clancy CE, Furukawa T. Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes. Pharmacology & Therapeutics. PMID 27595633 DOI: 10.1016/J.Pharmthera.2016.09.004  0.449
2016 Kanda Y, Yamazaki D, Kurokawa J, Inutsuka T, Sekino Y. Points to consider for a validation study of iPS cell-derived cardiomyocytes using a multi-electrode array system. Journal of Pharmacological and Toxicological Methods. PMID 27369811 DOI: 10.1016/J.Vascn.2016.06.007  0.311
2016 Kanda Y, Ashihara T, Kurokawa J. [Development of mature cardiomyocytes from human iPS cells: toward cardiac safety assessment]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 147: 334-8. PMID 27301306 DOI: 10.1254/Fpj.147.334  0.331
2016 López-Redondo F, Kurokawa J, Nomura F, Kaneko T, Hamada T, Furukawa T, Yasuda K. A distribution analysis of action potential parameters obtained from patch-clamped human stem cell-derived cardiomyocytes. Journal of Pharmacological Sciences. PMID 27179939 DOI: 10.1016/J.Jphs.2016.04.015  0.683
2016 Sugiyama K, Sasano T, Kurokawa J, Takahashi K, Okamura T, Kato N, Isobe M, Furukawa T. Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice. International Heart Journal. PMID 27170476 DOI: 10.1536/Ihj.15-471  0.32
2016 Kanda Y, Li M, Ashihara T, Sekino Y, Furukawa T, Kurokawa J. Assessment of drug-induced QT prolongation using human iPS cell-derived mature cardiomyocytes Journal of Pharmacological and Toxicological Methods. 81: 384. DOI: 10.1016/J.Vascn.2016.02.159  0.306
2016 Okada J, Yoshinaga T, Kurokawa J, Washio T, Furukawa T, Sawada K, Sugiura S, Hisada T. Cardiac safety assessment of drugs using three-dimensional heart simulator Journal of Pharmacological and Toxicological Methods. 81: 351. DOI: 10.1016/J.Vascn.2016.02.054  0.308
2016 Yang P, Wang Y, Perissinotti LL, Kurokawa J, DeMarco KR, Jeng M, Harvey RD, Clancy CE. An in Silico Study of Female Susceptibility to Arousal-Induced Arrhythmias Biophysical Journal. 110: 585a. DOI: 10.1016/J.Bpj.2015.11.3126  0.403
2015 Yamakawa H, Muraoka N, Miyamoto K, Sadahiro T, Isomi M, Haginiwa S, Kojima H, Umei T, Akiyama M, Kuishi Y, Kurokawa J, Furukawa T, Fukuda K, Ieda M. Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions. Stem Cell Reports. PMID 26626177 DOI: 10.1016/J.Stemcr.2015.10.019  0.35
2015 Okada JI, Yoshinaga T, Kurokawa J, Washio T, Furukawa T, Sawada K, Sugiura S, Hisada T. Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator. Science Advances. 1: e1400142. PMID 26601174 DOI: 10.1126/Sciadv.1400142  0.334
2015 Saito Y, Nakamura K, Yoshida M, Sugiyama H, Ohe T, Kurokawa J, Furukawa T, Takano M, Nagase S, Morita H, Kusano KF, Ito H. Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker. Plos One. 10: e0138193. PMID 26384234 DOI: 10.1371/Journal.Pone.0138193  0.374
2015 Kurokawa J, Sasano T, Kodama M, Li M, Ebana Y, Harada N, Honda S, Nakaya H, Furukawa T. Aromatase knockout mice reveal an impact of estrogen on drug-induced alternation of murine electrocardiography parameters. The Journal of Toxicological Sciences. 40: 339-48. PMID 25972195 DOI: 10.2131/Jts.40.339  0.417
2015 Yoshinaga T, Okada J, Kurokawa J, Taniguchi T, Furukawa T, Sugiura S, Hisada T, Sawada K. Multi-scale heart simulator, UT-heart is useful for proarrhythmia prediction based on cardiac multi-ion channel data Journal of Pharmacological and Toxicological Methods. 75: 172. DOI: 10.1016/J.Vascn.2015.08.049  0.387
2014 Li M, Kanda Y, Sekino Y, Furukawa T, Kurokawa J. A Novel Approach for Evaluation of Drug-Induced QT Prolongation using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Biophysical Journal. 106: 720a-721a. DOI: 10.1016/J.Bpj.2013.11.3981  0.377
2013 Kurokawa J, Furukawa T. Non-genomic action of sex steroid hormones and cardiac repolarization. Biological & Pharmaceutical Bulletin. 36: 8-12. PMID 23302631 DOI: 10.1248/Bpb.B212021  0.429
2013 Asayama M, Kurokawa J, Shirakawa K, Okuyama H, Kagawa T, Okada J, Sugiura S, Hisada T, Furukawa T. Effects of an hERG activator, ICA-105574, on electrophysiological properties of canine hearts. Journal of Pharmacological Sciences. 121: 1-8. PMID 23238536 DOI: 10.1254/Jphs.12220Fp  0.445
2013 Lopez-Redondo F, Kurokawa J, Nomura F, Kaneko T, Hamada T, Furukawa T, Yasuda K. 3P216 A comparative study on electrophysiological properties of human iPS- and ES-derived cardiomyocytes(13C. Biological & Artifical membrane: Excitation & Channels,Poster) Seibutsu Butsuri. 53. DOI: 10.2142/Biophys.53.S247_5  0.351
2013 López-Redondo F, Kurokawa J, Nomura F, Kaneko T, Hamada T, Yasuda K, Furukawa T. Human ES- and Induced Pluripotent Stem-Derived Cardiomyocytes. A Comparative Electrophysiological Study Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1658  0.348
2012 Kurokawa J, Kodama M, Furukawa T, Clancy CE. Sex and gender aspects in antiarrhythmic therapy. Handbook of Experimental Pharmacology. 237-63. PMID 23027454 DOI: 10.1007/978-3-642-30726-3_12  0.405
2012 Egashira T, Yuasa S, Suzuki T, Aizawa Y, Yamakawa H, Matsuhashi T, Ohno Y, Tohyama S, Okata S, Seki T, Kuroda Y, Yae K, Hashimoto H, Tanaka T, Hattori F, ... ... Kurokawa J, et al. Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovascular Research. 95: 419-29. PMID 22739119 DOI: 10.1093/Cvr/Cvs206  0.424
2011 Sugiyama H, Nakamura K, Morita H, Akagi S, Tani Y, Katayama Y, Nishii N, Miyoshi T, Nagase S, Kohno K, Kusano KF, Ohe T, Kurokawa J, Furukawa T, Ito H. Circulating KCNH2 current-activating factor in patients with heart failure and ventricular tachyarrhythmia. Plos One. 6: e19897. PMID 21625547 DOI: 10.1371/Journal.Pone.0019897  0.392
2011 Furukawa T, Kurokawa J, Asada K, Bai C, Nakamura H, Isobe M, E. Clancy C. Non-Genomic Regulation of K+ and Ca2+ Channels by Sex Hormones Journal of Arrhythmia. 27: SS2_1. DOI: 10.4020/Jhrs.27.Ss2_1  0.42
2010 Kurokawa J, Asada K, Furukawa T. [Nitric oxide and cardiac action potential]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 135: 95-8. PMID 20228572 DOI: 10.1254/Fpj.135.95  0.309
2010 Yang PC, Kurokawa J, Furukawa T, Clancy CE. Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study. Plos Computational Biology. 6: e1000658. PMID 20126530 DOI: 10.1371/Journal.Pcbi.1000658  0.424
2010 Kurokawa J, Asada K, Furukawa T. Regulation of the IKs Channel by S-nitrosylation at Carboxyl-Terminus of KCNQ1 Biophysical Journal. 98: 1-6. DOI: 10.1016/J.Bpj.2009.12.735  0.423
2009 Kurokawa J, Abriel H. Neurohormonal regulation of cardiac ion channels in chronic heart failure. Journal of Cardiovascular Pharmacology. 54: 98-105. PMID 19597366 DOI: 10.1097/Fjc.0B013E3181B2B6D4  0.623
2009 Kaihara A, Sunami A, Kurokawa J, Furukawa T. A genetically encoded bioluminescent indicator for the sodium channel activity in living cells. Journal of the American Chemical Society. 131: 4188-9. PMID 19271706 DOI: 10.1021/Ja808669Y  0.404
2009 Kurokawa J, Suzuki T, Furukawa T. New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: acute effects of female hormones on cardiac ion channels and cardiac repolarization. Journal of Pharmacological Sciences. 109: 334-40. PMID 19270425 DOI: 10.1254/Jphs.08R23Fm  0.457
2009 Kakusaka S, Asayama M, Kaihara A, Sasano T, Suzuki T, Kurokawa J, Furukawa T. A receptor-independent effect of estrone sulfate on the HERG channel. Journal of Pharmacological Sciences. 109: 152-6. PMID 19129680 DOI: 10.1254/Jphs.08257Sc  0.367
2009 Asada K, Kurokawa J, Furukawa T. Redox- and calmodulin-dependent S-nitrosylation of the KCNQ1 channel. The Journal of Biological Chemistry. 284: 6014-20. PMID 19124472 DOI: 10.1074/Jbc.M807158200  0.448
2009 Kurokawa J, Bankston JR, Kaihara A, Chen L, Furukawa T, Kass RS. KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. Channels (Austin, Tex.). 3: 16-24. PMID 19077539 DOI: 10.4161/Chan.3.1.7387  0.747
2009 Kurokawa J, Tamagawa M, Harada N, Honda S, Nakaya H, Furukawa T. Effects Of Estrogen On The IKr Channel And Cardiac Repolarization Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.798  0.387
2008 Furukawa T, Kurokawa J, Clancy CE. A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women. Current Cardiology Reviews. 4: 244-50. PMID 20066131 DOI: 10.2174/157340308786349507  0.4
2008 Furukawa T, Kurokawa J. Non-genomic regulation of cardiac ion channels by sex hormones. Cardiovascular & Hematological Disorders Drug Targets. 8: 245-51. PMID 19075634 DOI: 10.2174/187152908786786160  0.388
2008 Kurokawa J, Tamagawa M, Harada N, Honda S, Bai CX, Nakaya H, Furukawa T. Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization. The Journal of Physiology. 586: 2961-73. PMID 18440994 DOI: 10.1113/Jphysiol.2007.150367  0.436
2007 Asaoka H, Kurokawa J, Furukawa T, Shimokado K. High glucose concentrations impair the activation of K+ channels and proteases in undifferentiated THP-1 monocytes Journal of Medical and Dental Sciences. 54: 97-102. PMID 19845141 DOI: 10.11480/Jmds.540113  0.326
2007 Kurokawa J. Compartmentalized regulations of ion channels in the heart. Biological & Pharmaceutical Bulletin. 30: 2231-7. PMID 18057704 DOI: 10.1248/Bpb.30.2231  0.474
2007 Nakamura H, Kurokawa J, Bai CX, Asada K, Xu J, Oren RV, Zhu ZI, Clancy CE, Isobe M, Furukawa T. Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study. Circulation. 116: 2913-22. PMID 18056530 DOI: 10.1161/Circulationaha.107.702407  0.368
2007 Furukawa T, Kurokawa J. Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: implication for the gender difference in cardiac arrhythmias. Pharmacology & Therapeutics. 115: 106-15. PMID 17583354 DOI: 10.1016/J.Pharmthera.2007.04.008  0.441
2007 Tani Y, Miura D, Kurokawa J, Nakamura K, Ouchida M, Shimizu K, Ohe T, Furukawa T. T75M-KCNJ2 mutation causing Andersen-Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity. Journal of Molecular and Cellular Cardiology. 43: 187-96. PMID 17582433 DOI: 10.1016/J.Yjmcc.2007.05.005  0.44
2006 Furukawa T, Bai CX, Kaihara A, Ozaki E, Kawano T, Nakaya Y, Awais M, Sato M, Umezawa Y, Kurokawa J. Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones. Molecular Pharmacology. 70: 1916-24. PMID 16985185 DOI: 10.1124/Mol.106.028134  0.433
2006 Furukawa T, Kurokawa J. Potassium channel remodeling in cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 41: 753-61. PMID 16962130 DOI: 10.1016/J.Yjmcc.2006.07.021  0.44
2006 Marx SO, Kurokawa J. AKAPs as antiarrhythmic targets? Handbook of Experimental Pharmacology. 171: 221-233. PMID 16610346 DOI: 10.1007/3-540-29715-4_8  0.407
2005 Kurokawa J, Furukawa T. [Protein modification of cardiac potassium channels and lethal arrhythmias]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 126: 273-9. PMID 16327209 DOI: 10.1254/Fpj.126.273  0.442
2005 Bai CX, Kurokawa J, Tamagawa M, Nakaya H, Furukawa T. Nontranscriptional regulation of cardiac repolarization currents by testosterone. Circulation. 112: 1701-10. PMID 16157773 DOI: 10.1161/Circulationaha.104.523217  0.37
2005 Shushi L, Kerem B, Goldmit M, Peretz A, Attali B, Medina A, Towbin JA, Kurokawa J, Kass RS, Benhorin J. Clinical, genetic, and electrophysiologic characteristics of a new PAS-domain HERG mutation (M124R) causing Long QT syndrome. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 10: 334-41. PMID 16029385 DOI: 10.1111/J.1542-474X.2005.00643.X  0.531
2005 Chen L, Kurokawa J, Kass RS. Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel. The Journal of Biological Chemistry. 280: 31347-52. PMID 16002409 DOI: 10.1074/Jbc.M505191200  0.587
2004 Kurokawa J, Motoike HK, Rao J, Kass RS. Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 16374-8. PMID 15528278 DOI: 10.1073/Pnas.0405583101  0.617
2004 Dilly KW, Kurokawa J, Terrenoire C, Reiken S, Lederer WJ, Marks AR, Kass RS. Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization. The Journal of Biological Chemistry. 279: 40778-87. PMID 15272004 DOI: 10.1074/Jbc.M406010200  0.531
2003 Tateyama M, Kurokawa J, Terrenoire C, Rivolta I, Kass RS. Stimulation of protein kinase C inhibits bursting in disease-linked mutant human cardiac sodium channels. Circulation. 107: 3216-22. PMID 12796143 DOI: 10.1161/01.Cir.0000070936.65183.97  0.622
2003 Kass RS, Kurokawa J, Marx SO, Marks AR. Leucine/isoleucine zipper coordination of ion channel macromolecular signaling complexes in the heart. Roles in inherited arrhythmias. Trends in Cardiovascular Medicine. 13: 52-6. PMID 12586439 DOI: 10.1016/S1050-1738(02)00211-6  0.611
2003 Kurokawa J, Chen L, Kass RS. Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 100: 2122-7. PMID 12566567 DOI: 10.1073/Pnas.0434935100  0.628
2003 Clancy CE, Kurokawa J, Tateyama M, Wehrens XH, Kass RS. K+ channel structure-activity relationships and mechanisms of drug-induced QT prolongation. Annual Review of Pharmacology and Toxicology. 43: 441-61. PMID 12540747 DOI: 10.1146/Annurev.Pharmtox.43.100901.140245  0.586
2003 Chiello Tracy C, Cabo C, Coromilas J, Kurokawa J, Kass RS, Wit AL. Electrophysiological consequences of human IKs channel expression in adult murine heart. American Journal of Physiology. Heart and Circulatory Physiology. 284: H168-75. PMID 12388269 DOI: 10.1152/Ajpheart.00661.2002  0.603
2002 Marx SO, Kurokawa J, Reiken S, Motoike H, D'Armiento J, Marks AR, Kass RS. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science (New York, N.Y.). 295: 496-9. PMID 11799244 DOI: 10.1126/Science.1066843  0.63
2001 Kurokawa J, Abriel H, Kass RS. Molecular basis of the delayed rectifier current I(ks)in heart. Journal of Molecular and Cellular Cardiology. 33: 873-82. PMID 11343411 DOI: 10.1006/Jmcc.2001.1377  0.703
2001 Kurokawa J, Motoike HK, Kass RS. TEA(+)-sensitive KCNQ1 constructs reveal pore-independent access to KCNE1 in assembled I(Ks) channels. The Journal of General Physiology. 117: 43-52. PMID 11134230 DOI: 10.1085/Jgp.117.1.43  0.6
1997 Kurokawa J, Adachi-Akahane S, Nagao T. 1,5-benzothiazepine binding domain is located on the extracellular side of the cardiac L-type Ca2+ channel. Molecular Pharmacology. 51: 262-268. PMID 9203631 DOI: 10.1124/Mol.51.2.262  0.328
1997 Kurokawa J, Adachi-Akahane S, Nagao T. Effects of a novel, potent benzothiazepine Ca2+ channel antagonist, DTZ323, on guinea-pig ventricular myocytes European Journal of Pharmacology. 325: 229-236. PMID 9163570 DOI: 10.1016/S0014-2999(97)00119-2  0.357
1997 Kanda S, Kurokawa J, Adachi-Akahane S, Nagao T. Diltiazem derivatives modulate the dihydropyridine-binding to intact rat ventricular myocytes European Journal of Pharmacology. 319: 101-107. PMID 9030904 DOI: 10.1016/S0014-2999(96)00826-6  0.305
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