| Year |
Citation |
Score |
| 2020 |
Maculins T, Garcia-Pardo J, Skenderovic A, Gebel J, Putyrski M, Vorobyov A, Busse P, Varga G, Kuzikov M, Zaliani A, Rahighi S, Schaeffer V, Parnham MJ, Sidhu SS, Ernst A, et al. Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chemical Biology. PMID 32726587 DOI: 10.1016/J.Chembiol.2020.07.010 |
0.525 |
|
| 2020 |
Putyrski M, Vakhrusheva O, Bonn F, Guntur S, Vorobyov A, Brandts C, Dikic I, Ernst A. Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine. Frontiers in Cell and Developmental Biology. 8: 208. PMID 32296703 DOI: 10.3389/Fcell.2020.00208 |
0.544 |
|
| 2019 |
Teyra J, Ernst A, Singer A, Sicheri F, Sidhu SS. Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Science : a Publication of the Protein Society. PMID 31654425 DOI: 10.1002/Pro.3759 |
0.345 |
|
| 2019 |
Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, et al. Deubiquitinase USP10 regulates Notch signaling in the endothelium. Science (New York, N.Y.). 364: 188-193. PMID 30975888 DOI: 10.1126/Science.Aat0778 |
0.457 |
|
| 2019 |
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M. Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife. 8. PMID 30838976 DOI: 10.7554/Elife.42549 |
0.469 |
|
| 2019 |
Manczyk N, Veggiani G, Gish GD, Yates BP, Ernst A, Sidhu SS, Sicheri F. Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif. Protein Science : a Publication of the Protein Society. PMID 30793400 DOI: 10.1002/Pro.3593 |
0.323 |
|
| 2019 |
Wegner M, Diehl V, Bittl V, Bruyn Rd, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M. Author response: Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome Elife. DOI: 10.7554/Elife.42549.044 |
0.427 |
|
| 2017 |
Wiechmann S, Gärtner A, Kniss A, Stengl A, Behrends C, Rogov VV, Rodriguez MS, Dötsch V, Müller S, Ernst A. Site-specific inhibition of the SUMO-conjugating enzyme Ubc9 selectively impairs SUMO chain formation. The Journal of Biological Chemistry. PMID 28784659 DOI: 10.1074/Jbc.M117.794255 |
0.381 |
|
| 2017 |
Zhang W, Sartori MA, Makhnevych T, Federowicz KE, Dong X, Liu L, Nim S, Dong A, Yang J, Li Y, Haddad D, Ernst A, Heerding D, Tong Y, Moffat J, et al. Generation and validation of intracellular ubiquitin variant inhibitors for USP7 and USP10. Journal of Molecular Biology. PMID 28587923 DOI: 10.1016/J.Jmb.2017.05.025 |
0.344 |
|
| 2017 |
Manczyk N, Yates BP, Veggiani G, Ernst A, Sicheri F, Sidhu SS. Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif. Protein Science : a Publication of the Protein Society. PMID 28276594 DOI: 10.1002/Pro.3155 |
0.386 |
|
| 2017 |
Wiechmann S, Ernst A. Engineering von intrazellulären Modulatoren Biospektrum. 23: 769-771. DOI: 10.1007/S12268-017-0870-9 |
0.332 |
|
| 2016 |
Stolz A, Putyrski M, Kutle I, Huber J, Wang C, Major V, Sidhu SS, Youle RJ, Rogov VV, Dötsch V, Ernst A, Dikic I. Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins. The Embo Journal. PMID 28028054 DOI: 10.15252/Embj.201695063 |
0.638 |
|
| 2014 |
Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS. A structural portrait of the PDZ domain family. Journal of Molecular Biology. 426: 3509-19. PMID 25158098 DOI: 10.1016/J.Jmb.2014.08.012 |
0.323 |
|
| 2014 |
Stolz A, Ernst A, Dikic I. Cargo recognition and trafficking in selective autophagy. Nature Cell Biology. 16: 495-501. PMID 24875736 DOI: 10.1038/Ncb2979 |
0.631 |
|
| 2014 |
Gfeller D, Ernst A, Jarvik N, Sidhu SS, Bader GD. Prediction and experimental characterization of nsSNPs altering human PDZ-binding motifs. Plos One. 9: e94507. PMID 24722214 DOI: 10.1371/Journal.Pone.0094507 |
0.351 |
|
| 2013 |
Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, et al. A strategy for modulation of enzymes in the ubiquitin system. Science (New York, N.Y.). 339: 590-5. PMID 23287719 DOI: 10.1126/Science.1230161 |
0.328 |
|
| 2011 |
Gfeller D, Butty F, Wierzbicka M, Verschueren E, Vanhee P, Huang H, Ernst A, Dar N, Stagljar I, Serrano L, Sidhu SS, Bader GD, Kim PM. The multiple-specificity landscape of modular peptide recognition domains. Molecular Systems Biology. 7: 484. PMID 21525870 DOI: 10.1038/Msb.2011.18 |
0.354 |
|
| 2010 |
Ernst A, Gfeller D, Kan Z, Seshagiri S, Kim PM, Bader GD, Sidhu SS. Coevolution of PDZ domain-ligand interactions analyzed by high-throughput phage display and deep sequencing. Molecular Biosystems. 6: 1782-90. PMID 20714644 DOI: 10.1039/C0Mb00061B |
0.332 |
|
| 2009 |
Ernst A, Sazinsky SL, Hui S, Currell B, Dharsee M, Seshagiri S, Bader GD, Sidhu SS. Rapid evolution of functional complexity in a domain family. Science Signaling. 2: ra50. PMID 19738200 DOI: 10.1126/Scisignal.2000416 |
0.323 |
|
| 2004 |
Matsuura T, Ernst A, Zechel DL, Plückthun A. Combinatorial approaches to novel proteins. Chembiochem : a European Journal of Chemical Biology. 5: 177-82. PMID 14760738 DOI: 10.1002/Cbic.200300755 |
0.328 |
|
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