| Year |
Citation |
Score |
| 2023 |
Torres-Ayuso P, Katerji M, Mehlich D, Lookingbill SA, Sabbasani VR, Liou H, Casillas AL, Chauhan SS, Serwa R, Rubin MR, Marusiak AA, Swenson RE, Warfel NA, Brognard J. PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer. Cell Chemical Biology. PMID 38016478 DOI: 10.1016/j.chembiol.2023.10.023 |
0.691 |
|
| 2023 |
Jensen CC, Clements AN, Liou H, Ball LE, Bethard JR, Langlais PR, Toth RK, Chauhan SS, Casillas AL, Daulat SR, Kraft AS, Cress AE, Miranti CK, Mouneimne G, Rogers GC, ... Warfel NA, et al. PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion. The Journal of Cell Biology. 222. PMID 37042842 DOI: 10.1083/jcb.202208136 |
0.407 |
|
| 2022 |
Clements AN, Warfel NA. Targeting PIM Kinases to Improve the Efficacy of Immunotherapy. Cells. 11. PMID 36429128 DOI: 10.3390/cells11223700 |
0.391 |
|
| 2022 |
Toth RK, Solomon R, Warfel NA. Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28. Cells. 11. PMID 35326457 DOI: 10.3390/cells11061006 |
0.431 |
|
| 2022 |
Warfel NA. Defining the mechanisms underlying cyclin dependent kinase control of HIF-1α. Oncotarget. 13: 454-455. PMID 35251493 DOI: 10.18632/oncotarget.28208 |
0.367 |
|
| 2021 |
Casillas AL, Chauhan SS, Toth RK, Sainz AG, Clements AN, Jensen CC, Langlais PR, Miranti CK, Cress AE, Warfel NA. Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors. Oncogene. PMID 34211090 DOI: 10.1038/s41388-021-01915-1 |
0.351 |
|
| 2020 |
Toth RK, Warfel NA. Targeting PIM Kinases to Overcome Therapeutic Resistance in Cancer. Molecular Cancer Therapeutics. PMID 33303645 DOI: 10.1158/1535-7163.MCT-20-0535 |
0.449 |
|
| 2019 |
Toth RK, Tran JD, Muldong MT, Nollet EA, Schulz VV, Jensen CC, Hazlehurst LA, Corey E, Durden D, Jamieson C, Miranti CK, Warfel NA. Hypoxia-induced PIM kinase and laminin-activated integrin α6 mediate resistance to PI3K inhibitors in bone-metastatic CRPC. American Journal of Clinical and Experimental Urology. 7: 297-312. PMID 31511835 |
0.37 |
|
| 2018 |
Chauhan SS, Warfel NA. Targeting PIM kinases to oppose hypoxia-mediated therapeutic resistance. Oncoscience. 5: 254-255. PMID 30460324 DOI: 10.18632/oncoscience.458 |
0.344 |
|
| 2018 |
Song JH, Singh N, Luevano LA, Padi SKR, Okumura K, Olive V, Black SM, Warfel NA, Goodrich DW, Kraft AS. Mechanisms behind resistance to PI3K Inhibitor treatment induced by the PIM kinase. Molecular Cancer Therapeutics. PMID 30190422 DOI: 10.1158/1535-7163.MCT-18-0374 |
0.491 |
|
| 2017 |
Casillas AL, Toth RK, Sainz AG, Singh N, Desai AA, Kraft AS, Warfel NA. Hypoxia-inducible PIM kinase expression promotes resistance to anti-angiogenic agents. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29084916 DOI: 10.1158/1078-0432.CCR-17-1318 |
0.356 |
|
| 2016 |
Warfel NA, Sainz AG, Song JH, Kraft AS. PIM kinase inhibitors kill hypoxic tumor cells by reducing Nrf2 signaling and increasing reactive oxygen species. Molecular Cancer Therapeutics. PMID 27196781 DOI: 10.1158/1535-7163.MCT-15-1018 |
0.429 |
|
| 2015 |
Warfel NA, Kraft AS. PIM kinase (and Akt) biology and signaling in tumors. Pharmacology & Therapeutics. 151: 41-49. PMID 25749412 DOI: 10.1016/j.pharmthera.2015.03.001 |
0.416 |
|
| 2013 |
Warfel NA, Dolloff NG, Dicker DT, Malysz J, El-Deiry WS. CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth. Cell Cycle (Georgetown, Tex.). 12: 3689-701. PMID 24189531 DOI: 10.4161/Cc.26930 |
0.326 |
|
| 2013 |
Zhang S, Zhou L, Hong B, Warfel N, heuvel AVd, Dicker D, Kopelovich L, El-Deiry W. Abstract 2171: A new small molecule compound restoring p53 pathway induces cell death via active p73 and degradation of mutant p53 in colorectal cancer cells. Cancer Research. 73: 2171-2171. DOI: 10.1158/1538-7445.Am2013-2171 |
0.32 |
|
| 2013 |
Das A, Dicker DT, Harouaka R, Zheng S, Warfel N, Staveley-O'Carroll KF, El-Deiry WS, Kaifi JT. Abstract 1452: Perioperative detection of circulating tumor cells in patients undergoing colorectal cancer liver and lung metastasectomy : Comparing CellSearch and FMSA technologies and investigating the role of EMT . Cancer Research. 73: 1452-1452. DOI: 10.1158/1538-7445.Am2013-1452 |
0.303 |
|
| 2012 |
Warfel NA, Newton AC. Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling. The Journal of Biological Chemistry. 287: 3610-6. PMID 22144674 DOI: 10.1074/Jbc.R111.318675 |
0.702 |
|
| 2011 |
Warfel NA, Niederst M, Newton AC. Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2. The Journal of Biological Chemistry. 286: 39122-9. PMID 21908613 DOI: 10.1074/Jbc.M111.278747 |
0.683 |
|
| 2011 |
Warfel NA, Niederst M, Stevens MW, Brennan PM, Frame MC, Newton AC. Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt Journal of Biological Chemistry. 286: 19777-19788. PMID 21454620 DOI: 10.1074/Jbc.M111.237081 |
0.64 |
|
| 2009 |
Brognard J, Niederst M, Reyes G, Warfel N, Newton AC. Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C. The Journal of Biological Chemistry. 284: 15215-23. PMID 19324870 DOI: 10.1074/Jbc.M901468200 |
0.594 |
|
| 2007 |
Gills JJ, Castillo SS, Zhang C, Petukhov PA, Memmott RM, Hollingshead M, Warfel N, Han J, Kozikowski AP, Dennis PA. Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38α, through MKK3/6-independent and -dependent mechanisms Journal of Biological Chemistry. 282: 27020-27029. PMID 17631503 DOI: 10.1074/Jbc.M701108200 |
0.538 |
|
| 2007 |
Granville CA, Warfel N, Tsurutani J, Hollander MC, Robertson M, Fox SD, Veenstra TD, Issaq HJ, Linnoila RI, Dennis PA. Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2281-9. PMID 17404113 DOI: 10.1158/1078-0432.Ccr-06-2570 |
0.348 |
|
| 2006 |
Warfel NA, Lepper ER, Zhang C, Figg WD, Dennis PA. Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3502-9. PMID 16740776 DOI: 10.1158/1078-0432.Ccr-05-1837 |
0.336 |
|
| Show low-probability matches. |