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Vishnu Damalanka - Publications

Affiliations: 
2017- Biochemistry and Molecular Biophysic Washington University, Saint Louis, St. Louis, MO 
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Damalanka VC, Banas V, De Bona P, Kashipathy MM, Battaile K, Lovell S, Janetka JW. Mechanism-Based Macrocyclic Inhibitors of Serine Proteases. Journal of Medicinal Chemistry. PMID 38477709 DOI: 10.1021/acs.jmedchem.3c02388  0.681
2024 Jones VT, Graves-Deal R, Cao Z, Bogatcheva G, Ramirez MA, Harmych SJ, Higginbotham JN, Sharma V, Damalanka VC, Wahoski CC, Joshi N, Irudayam MJ, Roland JT, Ayers GD, Liu Q, et al. Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer. Cellular and Molecular Life Sciences : Cmls. 81: 28. PMID 38212428 DOI: 10.1007/s00018-023-05071-5  0.653
2023 Mekapogu AR, Xu Z, Pothula S, Perera C, Pang T, Hosen SMZ, Damalanka V, Janetka J, Goldstein D, Pirola R, Wilson J, Apte M. HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis. Cancer Letters. 568: 216286. PMID 37354984 DOI: 10.1016/j.canlet.2023.216286  0.656
2021 Damalanka VC, Voss JJLP, Mahoney MW, Primeau T, Li S, Klampfer L, Janetka JW. Macrocyclic Inhibitors of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression. Journal of Medicinal Chemistry. 64: 18158-18174. PMID 34902246 DOI: 10.1021/acs.jmedchem.1c01671  0.7
2021 Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenço AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz NP, Klingler AM, Rothlauf PW, Thompson CE, Lee M, et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34635581 DOI: 10.1073/pnas.2108728118  0.753
2021 Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenco AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz N, Klingler AM, Rothlauf PW, Thompson CE, Lee M, et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Biorxiv : the Preprint Server For Biology. PMID 34131661 DOI: 10.1101/2021.05.06.442935  0.755
2020 Damalanka VC, Maddirala AR, Janetka JW. Novel approaches to glycomimetic design: Development of small molecular weight lectin antagonists. Expert Opinion On Drug Discovery. PMID 33337918 DOI: 10.1080/17460441.2021.1857721  0.669
2019 Damalanka VC, Wildman SA, Janetka JW. Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin. Medchemcomm. 10: 1646-1655. PMID 31803403 DOI: 10.1039/C9Md00234K  0.735
2019 Damalanka VC, Janetka JW. Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2. Future Medicinal Chemistry. PMID 30945556 DOI: 10.4155/Fmc-2018-0446  0.68
2018 Damalanka VC, Han Z, Karmakar P, O'Donoghue AJ, La Greca F, Kim T, Pant S, Helander J, Klefström J, Craik CS, Janetka JW. Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology. Journal of Medicinal Chemistry. PMID 30571119 DOI: 10.1021/Acs.Jmedchem.8B01536  0.547
2018 Galasiti Kankanamalage AC, Kim Y, Damalanka VC, Rathnayake AD, Fehr AR, Mehzabeen N, Battaile KP, Lovell S, Lushington GH, Perlman S, Chang KO, Groutas WC. Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. European Journal of Medicinal Chemistry. 150: 334-346. PMID 29544147 DOI: 10.1016/J.Ejmech.2018.03.004  0.336
2018 Damalanka VC, Kim Y, Galasiti Kankanamalage AC, Rathnayake AD, Mehzabeen N, Battaile KP, Lovell S, Nguyen HN, Lushington GH, Chang KO, Groutas WC. Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease. European Journal of Medicinal Chemistry. 143: 881-890. PMID 29227928 DOI: 10.1016/J.Ejmech.2017.12.014  0.348
2016 Damalanka VC, Kim Y, Galasiti Kankanamalage AC, Lushington GH, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease. European Journal of Medicinal Chemistry. 127: 41-61. PMID 28038326 DOI: 10.1016/J.Ejmech.2016.12.033  0.404
2016 Galasiti Kankanamalage AC, Kim Y, Rathnayake AD, Damalanka VC, Weerawarna PM, Doyle ST, Alsoudi AF, Dissanayake DM, Lushington GH, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. European Journal of Medicinal Chemistry. 126: 502-516. PMID 27914364 DOI: 10.1016/J.Ejmech.2016.11.027  0.339
2016 Weerawarna PM, Kim Y, Galasiti Kankanamalage AC, Damalanka VC, Lushington GH, Alliston KR, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies. European Journal of Medicinal Chemistry. 119: 300-318. PMID 27235842 DOI: 10.1016/J.Ejmech.2016.04.013  0.347
2016 Damalanka VC, Kim Y, Alliston KR, Weerawarna PM, Galasiti Kankanamalage AC, Lushington GH, Mehzabeen N, Battaile KP, Lovell SW, Chang KO, Groutas WC. Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease. Journal of Medicinal Chemistry. PMID 26823007 DOI: 10.1021/Acs.Jmedchem.5B01464  0.381
2015 Galasiti Kankanamalage AC, Kim Y, Weerawarna PM, Uy RA, Damalanka VC, Mandadapu SR, Alliston KR, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies. Journal of Medicinal Chemistry. 58: 3144-55. PMID 25761614 DOI: 10.1021/Jm5019934  0.33
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