Year |
Citation |
Score |
2023 |
Boegholm N, Petriman NA, Loureiro-López M, Wang J, Vela MIS, Liu B, Kanie T, Ng R, Jackson PK, Andersen JS, Lorentzen E. The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport. The Embo Journal. e111807. PMID 37606072 DOI: 10.15252/embj.2022111807 |
0.359 |
|
2022 |
Petriman NA, Loureiro-López M, Taschner M, Zacharia NK, Georgieva MM, Boegholm N, Wang J, Mourão A, Russell RB, Andersen JS, Lorentzen E. Biochemically validated structural model of the 15-subunit intraflagellar transport complex IFT-B. The Embo Journal. e112440. PMID 36354106 DOI: 10.15252/embj.2022112440 |
0.315 |
|
2022 |
Langousis G, Cavadini S, Boegholm N, Lorentzen E, Kempf G, Matthias P. Structure of the ciliogenesis-associated CPLANE complex. Science Advances. 8: eabn0832. PMID 35427153 DOI: 10.1126/sciadv.abn0832 |
0.338 |
|
2021 |
Taschner M, Basquin J, Steigenberger B, Schäfer IB, Soh YM, Basquin C, Lorentzen E, Räschle M, Scheltema RA, Gruber S. Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding. The Embo Journal. e107807. PMID 34191293 DOI: 10.15252/embj.2021107807 |
0.597 |
|
2020 |
Petriman NA, Lorentzen E. Structural insights into the architecture and assembly of eukaryotic flagella. Microbial Cell (Graz, Austria). 7: 289-299. PMID 33150161 DOI: 10.15698/mic2020.11.734 |
0.308 |
|
2020 |
Wang J, Taschner M, Petriman NA, Andersen MB, Basquin J, Bhogaraju S, Vetter M, Wachter S, Lorentzen A, Lorentzen E. Purification and crystal structure of human ODA16: implications for ciliary import of outer dynein arms by the intraflagellar transport machinery. Protein Science : a Publication of the Protein Society. PMID 32239748 DOI: 10.1002/Pro.3864 |
0.44 |
|
2020 |
Petriman NA, Lorentzen E. Moving proteins along in the cilium. Elife. 9. PMID 32052743 DOI: 10.7554/Elife.55254 |
0.38 |
|
2020 |
Lorentzen E. Decision letter: Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes Elife. DOI: 10.7554/Elife.55954.Sa1 |
0.312 |
|
2019 |
Walia V, Cuenca A, Vetter M, Insinna C, Perera S, Lu Q, Ritt DA, Semler E, Specht S, Stauffer J, Morrison DK, Lorentzen E, Westlake CJ. Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis. Developmental Cell. PMID 31204173 DOI: 10.1016/J.Devcel.2019.05.022 |
0.306 |
|
2019 |
Deretic D, Lorentzen E, Fresquez T. The ins and outs of the Arf4-based ciliary membrane-targeting complex. Small Gtpases. 1-12. PMID 31068062 DOI: 10.1080/21541248.2019.1616355 |
0.39 |
|
2019 |
Dupont MA, Humbert C, Huber C, Siour Q, Guerrera IC, Jung V, Christensen A, Pouliet A, Garfa-Traore M, Nitschké P, Injeyan M, Millar K, Chitayat D, Shannon P, Girisha KM, ... ... Lorentzen E, et al. Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion. Human Molecular Genetics. PMID 31042281 DOI: 10.1093/Hmg/Ddz091 |
0.327 |
|
2019 |
Wachter S, Jung J, Shafiq S, Basquin J, Fort C, Bastin P, Lorentzen E. Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly. The Embo Journal. PMID 30940671 DOI: 10.15252/Embj.2018101251 |
0.444 |
|
2019 |
Bachmaier S, Volpato Santos Y, Kramer S, Githure GB, Klöckner T, Pepperl J, Baums C, Schenk R, Schwede F, Genieser HG, Dupuy JW, Forné I, Imhof A, Basquin J, Lorentzen E, et al. Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma. Nature Communications. 10: 1421. PMID 30926779 DOI: 10.1038/S41467-019-09338-Z |
0.39 |
|
2019 |
Lorentzen E, Kikkawa M. Decision letter: Structure and activation mechanism of the BBSome membrane protein trafficking complex Elife. DOI: 10.7554/Elife.53322.Sa1 |
0.366 |
|
2018 |
Wang Q, Taschner M, Ganzinger KA, Kelley C, Villasenor A, Heymann M, Schwille P, Lorentzen E, Mizuno N. Membrane association and remodeling by intraflagellar transport protein IFT172. Nature Communications. 9: 4684. PMID 30409972 DOI: 10.1038/S41467-018-07037-9 |
0.362 |
|
2018 |
Wingfield JL, Lechtreck KF, Lorentzen E. Trafficking of ciliary membrane proteins by the intraflagellar transport/BBSome machinery. Essays in Biochemistry. PMID 30287585 DOI: 10.1042/Ebc20180030 |
0.366 |
|
2018 |
Taschner M, Lorentzen A, Mourão A, Collins T, Freke GM, Moulding D, Basquin J, Jenkins D, Lorentzen E. Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis. Elife. 7. PMID 29658880 DOI: 10.7554/Elife.33067 |
0.407 |
|
2018 |
Vetter M, Boegholm N, Christensen A, Bhogaraju S, Andersen MB, Lorentzen A, Lorentzen E. Crystal structure of tetrameric human Rabin8 GEF domain. Proteins. PMID 29318657 DOI: 10.1002/Prot.25455 |
0.411 |
|
2018 |
Taschner M, Lorentzen A, Mourão A, Collins T, Freke GM, Moulding D, Basquin J, Jenkins D, Lorentzen E. Author response: Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis Elife. DOI: 10.7554/Elife.33067.030 |
0.381 |
|
2017 |
Taulet N, Vitre B, Anguille C, Douanier A, Rocancourt M, Taschner M, Lorentzen E, Echard A, Delaval B. IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning. Nature Communications. 8: 1928. PMID 29203870 DOI: 10.1038/S41467-017-01479-3 |
0.34 |
|
2017 |
Steger M, Diez F, Dhekne HS, Lis P, Nirujogi RS, Karayel O, Tonelli F, Martinez TN, Lorentzen E, Pfeffer SR, Alessi DR, Mann M. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. Elife. 6. PMID 29125462 DOI: 10.7554/Elife.31012 |
0.329 |
|
2017 |
Lv B, Wan L, Taschner M, Cheng X, Lorentzen E, Huang K. Intraflagellar transport protein IFT52 recruits IFT46 to the basal body and flagella. Journal of Cell Science. PMID 28302912 DOI: 10.1242/Jcs.200758 |
0.317 |
|
2017 |
Taschner M, Mourão A, Awasthi M, Basquin J, Lorentzen E. Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46. The Journal of Biological Chemistry. PMID 28298440 DOI: 10.1074/Jbc.M117.780155 |
0.423 |
|
2016 |
Taschner M, Lorentzen E. Recombinant Reconstitution and Purification of the IFT-B Core Complex from Chlamydomonas reinhardtii. Methods in Molecular Biology (Clifton, N.J.). 1454: 69-82. PMID 27514916 DOI: 10.1007/978-1-4939-3789-9_5 |
0.45 |
|
2016 |
Mourão A, Christensen ST, Lorentzen E. The intraflagellar transport machinery in ciliary signaling. Current Opinion in Structural Biology. 41: 98-108. PMID 27393972 DOI: 10.1016/J.Sbi.2016.06.009 |
0.308 |
|
2016 |
Taschner M, Lorentzen E. The Intraflagellar Transport Machinery. Cold Spring Harbor Perspectives in Biology. 8. PMID 27352625 DOI: 10.1101/Cshperspect.A028092 |
0.318 |
|
2016 |
Basquin J, Taschner M, Lorentzen E. Complex Reconstitution from Individual Protein Modules. Advances in Experimental Medicine and Biology. 896: 305-14. PMID 27165333 DOI: 10.1007/978-3-319-27216-0_19 |
0.431 |
|
2016 |
Taschner M, Weber K, Mourão A, Vetter M, Awasthi M, Stiegler M, Bhogaraju S, Lorentzen E. Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex. The Embo Journal. 35: 773-90. PMID 26912722 DOI: 10.15252/Embj.201593164 |
0.466 |
|
2016 |
Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, et al. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases. Elife. 5. PMID 26824392 DOI: 10.7554/Elife.12813 |
0.314 |
|
2015 |
Bizet AA, Becker-Heck A, Ryan R, Weber K, Filhol E, Krug P, Halbritter J, Delous M, Lasbennes MC, Linghu B, Oakeley EJ, Zarhrate M, Nitschké P, Garfa-Traore M, Serluca F, ... ... Lorentzen E, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nature Communications. 6: 8666. PMID 26487268 DOI: 10.1038/Ncomms9666 |
0.324 |
|
2015 |
Vetter M, Wang J, Lorentzen E, Deretic D. Novel Topography of the Rab11-Effector Interaction Network Within a Ciliary Membrane Targeting Complex. Small Gtpases. 0. PMID 26399276 DOI: 10.1080/21541248.2015.1091539 |
0.381 |
|
2015 |
Perrault I, Halbritter J, Porath JD, Gérard X, Braun DA, Gee HY, Fathy HM, Saunier S, Cormier-Daire V, Thomas S, Attié-Bitach T, Boddaert N, Taschner M, Schueler M, Lorentzen E, et al. IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype. Journal of Medical Genetics. 52: 657-65. PMID 26275418 DOI: 10.1136/Jmedgenet-2014-102838 |
0.328 |
|
2015 |
Vetter M, Stehle R, Basquin C, Lorentzen E. Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11. Nature Structural & Molecular Biology. 22: 695-702. PMID 26258637 DOI: 10.1038/Nsmb.3065 |
0.404 |
|
2014 |
Mourão A, Nager AR, Nachury MV, Lorentzen E. Structural basis for membrane targeting of the BBSome by ARL6. Nature Structural & Molecular Biology. 21: 1035-41. PMID 25402481 DOI: 10.1038/Nsmb.2920 |
0.394 |
|
2014 |
Taschner M, Kotsis F, Braeuer P, Kuehn EW, Lorentzen E. Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly. The Journal of Cell Biology. 207: 269-82. PMID 25349261 DOI: 10.1083/Jcb.201408002 |
0.459 |
|
2014 |
Bhogaraju S, Lorentzen E. Crystal structure of a Chlamydomonas reinhardtii flagellar RabGAP TBC-domain at 1.8 Å resolution. Proteins. 82: 2282-7. PMID 24810373 DOI: 10.1002/Prot.24597 |
0.441 |
|
2014 |
Bhogaraju S, Weber K, Engel BD, Lechtreck KF, Lorentzen E. Getting tubulin to the tip of the cilium: one IFT train, many different tubulin cargo-binding sites? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 463-7. PMID 24616010 DOI: 10.1002/Bies.201400007 |
0.432 |
|
2013 |
Bhogaraju S, Cajanek L, Fort C, Blisnick T, Weber K, Taschner M, Mizuno N, Lamla S, Bastin P, Nigg EA, Lorentzen E. Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science (New York, N.Y.). 341: 1009-12. PMID 23990561 DOI: 10.1126/Science.1240985 |
0.398 |
|
2013 |
Bhogaraju S, Engel BD, Lorentzen E. Intraflagellar transport complex structure and cargo interactions. Cilia. 2: 10. PMID 23945166 DOI: 10.1186/2046-2530-2-10 |
0.378 |
|
2013 |
Taschner M, Basquin J, Benda C, Lorentzen E. Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 Å resolution Proteins: Structure, Function and Bioinformatics. 81: 1473-1478. PMID 23553965 DOI: 10.1002/Prot.24296 |
0.413 |
|
2012 |
Lorentzen E, Conti E. Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction. Archaea (Vancouver, B.C.). 2012: 721869. PMID 23319881 DOI: 10.1155/2012/721869 |
0.637 |
|
2012 |
Taschner M, Vetter M, Lorentzen E. Atomic resolution structure of human α-tubulin acetyltransferase bound to acetyl-CoA. Proceedings of the National Academy of Sciences of the United States of America. 109: 19649-54. PMID 23071318 DOI: 10.1073/Pnas.1209343109 |
0.359 |
|
2012 |
Mizuno N, Taschner M, Engel BD, Lorentzen E. Structural studies of ciliary components. Journal of Molecular Biology. 422: 163-80. PMID 22683354 DOI: 10.1016/J.Jmb.2012.05.040 |
0.451 |
|
2012 |
Taschner M, Bhogaraju S, Lorentzen E. Architecture and function of IFT complex proteins in ciliogenesis. Differentiation; Research in Biological Diversity. 83: S12-22. PMID 22118932 DOI: 10.1016/J.Diff.2011.11.001 |
0.443 |
|
2011 |
Taschner M, Bhogaraju S, Vetter M, Morawetz M, Lorentzen E. Biochemical mapping of interactions within the intraflagellar transport (IFT) B core complex: IFT52 binds directly to four other IFT-B subunits. The Journal of Biological Chemistry. 286: 26344-52. PMID 21642430 DOI: 10.1074/Jbc.M111.254920 |
0.416 |
|
2011 |
Malet H, Lorentzen E. Mechanisms of RNA recruitment by the exosome. Rna Biology. 8: 398-403. PMID 21558791 DOI: 10.4161/Rna.8.3.14993 |
0.514 |
|
2011 |
Bhogaraju S, Taschner M, Morawetz M, Basquin C, Lorentzen E. Crystal structure of the intraflagellar transport complex 25/27. The Embo Journal. 30: 1907-18. PMID 21505417 DOI: 10.1038/Emboj.2011.110 |
0.503 |
|
2010 |
Malet H, Topf M, Clare DK, Ebert J, Bonneau F, Basquin J, Drazkowska K, Tomecki R, Dziembowski A, Conti E, Saibil HR, Lorentzen E. RNA channelling by the eukaryotic exosome. Embo Reports. 11: 936-42. PMID 21072061 DOI: 10.1038/Embor.2010.164 |
0.594 |
|
2009 |
Bonneau F, Basquin J, Ebert J, Lorentzen E, Conti E. The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation. Cell. 139: 547-59. PMID 19879841 DOI: 10.1016/J.Cell.2009.08.042 |
0.647 |
|
2008 |
Lorentzen E, Conti E. Expression, reconstitution, and structure of an archaeal RNA degrading exosome. Methods in Enzymology. 447: 417-35. PMID 19161854 DOI: 10.1016/S0076-6879(08)02220-9 |
0.631 |
|
2008 |
Lorentzen E, Basquin J, Conti E. Structural organization of the RNA-degrading exosome. Current Opinion in Structural Biology. 18: 709-13. PMID 18955140 DOI: 10.1016/J.Sbi.2008.10.004 |
0.634 |
|
2008 |
Lorentzen E, Basquin J, Tomecki R, Dziembowski A, Conti E. Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family. Molecular Cell. 29: 717-28. PMID 18374646 DOI: 10.1016/J.Molcel.2008.02.018 |
0.637 |
|
2008 |
Pauluhn A, Ahmed H, Lorentzen E, Buchinger S, Schomburg D, Siebers B, Pohl E. Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins. 72: 35-43. PMID 18186475 DOI: 10.1002/Prot.21890 |
0.335 |
|
2007 |
Lorentzen E, Dziembowski A, Lindner D, Seraphin B, Conti E. RNA channelling by the archaeal exosome. Embo Reports. 8: 470-6. PMID 17380186 DOI: 10.1038/Sj.Embor.7400945 |
0.626 |
|
2007 |
Dziembowski A, Lorentzen E, Conti E, Séraphin B. A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nature Structural & Molecular Biology. 14: 15-22. PMID 17173052 DOI: 10.1038/Nsmb1184 |
0.595 |
|
2007 |
Oddone A, Lorentzen E, Basquin J, Gasch A, Rybin V, Conti E, Sattler M. Structural and biochemical characterization of the yeast exosome component Rrp40. Embo Reports. 8: 63-9. PMID 17159918 DOI: 10.1038/Sj.Embor.7400856 |
0.638 |
|
2006 |
Walter P, Klein F, Lorentzen E, Ilchmann A, Klug G, Evguenieva-Hackenberg E. Characterization of native and reconstituted exosome complexes from the hyperthermophilic archaeon Sulfolobus solfataricus. Molecular Microbiology. 62: 1076-89. PMID 17078816 DOI: 10.1111/J.1365-2958.2006.05393.X |
0.477 |
|
2006 |
Bono F, Ebert J, Lorentzen E, Conti E. The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. Cell. 126: 713-25. PMID 16923391 DOI: 10.1016/J.Cell.2006.08.006 |
0.587 |
|
2006 |
Lorentzen E, Conti E. The exosome and the proteasome: nano-compartments for degradation. Cell. 125: 651-4. PMID 16713559 DOI: 10.1016/J.Cell.2006.05.002 |
0.568 |
|
2005 |
Lorentzen E, Conti E. Structural basis of 3′ end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH core Molecular Cell. 20: 473-481. PMID 16285928 DOI: 10.1016/J.Molcel.2005.10.020 |
0.629 |
|
2005 |
Portnoy V, Evguenieva-Hackenberg E, Klein F, Walter P, Lorentzen E, Klug G, Schuster G. RNA polyadenylation in Archaea: not observed in Haloferax while the exosome polynucleotidylates RNA in Sulfolobus. Embo Reports. 6: 1188-93. PMID 16282984 DOI: 10.1038/Sj.Embor.7400571 |
0.432 |
|
2005 |
Lorentzen E, Walter P, Fribourg S, Evguenieva-Hackenberg E, Klug G, Conti E. The archaeal exosome core is a hexameric ring structure with three catalytic subunits Nature Structural and Molecular Biology. 12: 575-581. PMID 15951817 DOI: 10.1038/Nsmb952 |
0.643 |
|
2005 |
Lorentzen E, Siebers B, Hensel R, Pohl E. Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates. Biochemistry. 44: 4222-9. PMID 15766250 DOI: 10.1021/Bi048192O |
0.409 |
|
2004 |
Walden H, Taylor GL, Lorentzen E, Pohl E, Lilie H, Schramm A, Knura T, Stubbe K, Tjaden B, Hensel R. Structure and function of a regulated archaeal triosephosphate isomerase adapted to high temperature Journal of Molecular Biology. 342: 861-875. PMID 15342242 DOI: 10.1016/J.Jmb.2004.07.067 |
0.359 |
|
2004 |
Lorentzen E, Hensel R, Knura T, Ahmed H, Pohl E. Structural Basis of allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde 3-Phosphate dehydrogenase from Thermoproteus tenax. Journal of Molecular Biology. 341: 815-28. PMID 15288789 DOI: 10.1016/J.Jmb.2004.05.032 |
0.446 |
|
2004 |
Lorentzen E, Siebers B, Hensel R, Pohl E. Structure, function and evolution of the Archaeal class I fructose-1,6-bisphosphate aldolase Biochemical Society Transactions. 32: 259-263. PMID 15046584 DOI: 10.1042/Bst0320259 |
0.389 |
|
2003 |
Lorentzen E, Pohl E, Zwart P, Stark A, Russell RB, Knura T, Hensel R, Siebers B. Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins. The Journal of Biological Chemistry. 278: 47253-60. PMID 12941964 DOI: 10.1074/Jbc.M305922200 |
0.447 |
|
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