| Year |
Citation |
Score |
| 2023 |
Kang EY, Terzic T, Ghatage P, Woo L, Gorringe KL, Karnezis AN, Lee CH, Köbel M. TP53 as a Diagnostic Aid in the Distinction of Ovarian Mucinous Borderline Tumors From Mucinous Carcinoma. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. PMID 37406453 DOI: 10.1097/PGP.0000000000000967 |
0.316 |
|
| 2022 |
Tessier-Cloutier B, Grewal JK, Jones MR, Pleasance E, Shen Y, Cai E, Dunham C, Hoang L, Horst B, Huntsman DG, Ionescu D, Karnezis AN, Lee AF, Lee CH, Lee TH, et al. The impact of whole genome and transcriptome analysis (WGTA) on predictive biomarker discovery and diagnostic accuracy of advanced malignancies. The Journal of Pathology. Clinical Research. PMID 35257510 DOI: 10.1002/cjp2.265 |
0.318 |
|
| 2021 |
Huvila J, Cochrane DR, Ta M, Chow C, Greening K, Leung S, Karnezis AN, DiFeo A, Huntsman DG. STING pathway expression in low-grade serous carcinoma of the ovary: an unexpected therapeutic opportunity? The Journal of Pathology. Clinical Research. PMID 34138519 DOI: 10.1002/cjp2.230 |
0.32 |
|
| 2021 |
Schoolmeester JK, Folpe AL, Nair AA, Halling K, Sutton BC, Landers E, Karnezis AN, Dickson BC, Nucci MR, Kolin DL. EWSR1-WT1 gene fusions in neoplasms other than desmoplastic small round cell tumor: a report of three unusual tumors involving the female genital tract and review of the literature. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 34099870 DOI: 10.1038/s41379-021-00843-5 |
0.313 |
|
| 2021 |
Hoppe MM, Jaynes P, Wardyn JD, Upadhyayula SS, Tan TZ, Lie S, Lim DGZ, Pang BNK, Lim S, P S Yeong J, Karnezis A, Chiu DS, Leung S, Huntsman DG, Sedukhina AS, et al. Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer. Embo Molecular Medicine. e13366. PMID 33709473 DOI: 10.15252/emmm.202013366 |
0.31 |
|
| 2020 |
Karnezis AN, Chen SY, Chow C, Yang W, Hendricks WPD, Ramos P, Briones N, Mes-Masson AM, Bosse T, Gilks CB, Trent JM, Weissman B, Huntsman DG, Wang Y. Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines. Gynecologic Oncology. PMID 33328126 DOI: 10.1016/j.ygyno.2020.12.004 |
0.333 |
|
| 2020 |
Martins FC, Couturier DL, Paterson A, Karnezis AN, Chow C, Nazeran TM, Odunsi A, Gentry-Maharaj A, Vrvilo A, Hein A, Talhouk A, Osorio A, Hartkopf AD, Brooks-Wilson A, DeFazio A, et al. Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium. British Journal of Cancer. PMID 32555365 DOI: 10.1038/S41416-020-0900-0 |
0.356 |
|
| 2020 |
Ji JX, Cochrane DR, Tessier-Cloutier B, Chen SY, Ho G, Pathak KV, Alcazar IN, Farnell D, Leung S, Cheng A, Chow C, Colborne S, Negri GL, Kommoss F, Karnezis A, et al. Arginine depletion therapy with ADI-PEG20 limits tumor growth in argininosuccinate synthase deficient ovarian cancer, including small cell carcinoma of the ovary, hypercalcemic type. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32409304 DOI: 10.1158/1078-0432.Ccr-19-1905 |
0.469 |
|
| 2020 |
Chen H, Gotimer K, De Souza C, Tepper CG, Karnezis AN, Leiserowitz GS, Chien J, Smith LH. Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma. Gynecologic Oncology. PMID 32253045 DOI: 10.1016/j.ygyno.2020.03.026 |
0.313 |
|
| 2019 |
Zhouchunyang X, Cochrane DR, Tessier-Coutier B, Leung S, Karnezis AN, Cheng AS, Farnell DA, Magrill J, Schmidt D, Kommoss S, Kommoss FKF, Kommoss F, McAlpine JN, Gilks CB, Koebel M, et al. Expression of L1 retrotransposon open reading frame protein 1 (L1ORF1p) in gynecologic cancers. Human Pathology. PMID 31220479 DOI: 10.1016/j.humpath.2019.06.001 |
0.319 |
|
| 2019 |
Karnezis AN, Wang Y, Keul J, Tessier-Cloutier B, Magrill J, Kommoss S, Senz J, Yang W, Proctor L, Schmidt D, Clement PB, Gilks CB, Huntsman DG, Kommoss F. DICER1 and FOXL2 Mutation Status Correlates With Clinicopathologic Features in Ovarian Sertoli-Leydig Cell Tumors. The American Journal of Surgical Pathology. 43: 628-638. PMID 30986800 DOI: 10.1097/PAS.0000000000001232 |
0.332 |
|
| 2019 |
Gotimer K, Chen H, Tepper C, Karnezis A, Chien J, Leiserowitz GS, Smith LH. Short-term Organoid Culture For Drug Sensitivity Testing in High Grade Serous Ovarian Cancer Gynecologic Oncology. 156: 92-93. DOI: 10.1016/J.Ygyno.2019.11.086 |
0.314 |
|
| 2018 |
Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Dos Santos N, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, et al. Histone deacetylase inhibitors synergizes with catalytic inhibitors of EZH2 to exhibit anti-tumor activity in small cell carcinoma of the ovary, hypercalcemic type. Molecular Cancer Therapeutics. PMID 30232145 DOI: 10.1158/1535-7163.Mct-18-0348 |
0.327 |
|
| 2018 |
Zhang AW, McPherson A, Milne K, Kroeger DR, Hamilton PT, Miranda A, Funnell T, Little N, de Souza CPE, Laan S, LeDoux S, Cochrane DR, Lim JLP, Yang W, Roth A, ... ... Karnezis AN, et al. Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer. Cell. PMID 29754820 DOI: 10.1016/J.Cell.2018.03.073 |
0.366 |
|
| 2018 |
Kuwahara Y, Kennedy LM, Karnezis AN, Mora-Blanco EL, Rogers AB, Fletcher CD, Huntsman DG, Roberts CWM, Rathmell WK, Weissman BE. High Frequency of Ovarian Cyst Development in Vhl;Snf5 Mice. The American Journal of Pathology. PMID 29684361 DOI: 10.1016/J.Ajpath.2018.03.010 |
0.334 |
|
| 2018 |
Wang Y, Karnezis AN, Magrill J, Tessier-Cloutier B, Lum A, Senz J, Gilks CB, McCluggage WG, Huntsman DG, Kommoss F. DICER1 hotspot mutations in ovarian gynandroblastoma. Histopathology. PMID 29660837 DOI: 10.1111/his.13630 |
0.34 |
|
| 2018 |
Lang JD, Hendricks WPD, Orlando KA, Yin H, Kiefer J, Ramos P, Sharma R, Pirrotte P, Raupach EA, Sereduk C, Tang N, Liang WS, Washington M, Facista SJ, Zismann VL, ... ... Karnezis AN, et al. Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29440177 DOI: 10.1158/1078-0432.Ccr-17-1928 |
0.307 |
|
| 2018 |
Kommoss S, McConechy MK, Kommoss F, Leung S, Bunz A, Magrill J, Britton H, Kommoss F, Grevenkamp F, Karnezis A, Yang W, Lum A, Krämer B, Taran F, Staebler A, et al. Final Validation of the ProMisE Molecular Classifier for Endometrial Carcinoma in a Large Population-based Case Series. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 29432521 DOI: 10.1093/Annonc/Mdy058 |
0.381 |
|
| 2018 |
Wang Y, Chen SY, Colborne S, Orlando K, Lang J, Karnezis A, Hendricks W, Morin G, Weissman B, Trent J, Huntsman D. Abstract 3673: Targeting the epigenome of small cell hypercalcemic carcinoma of the ovary, hypercalcemic type (SCCOHT) Cancer Research. 78: 3673-3673. DOI: 10.1158/1538-7445.Am2018-3673 |
0.416 |
|
| 2017 |
Grewal JK, Eirew P, Jones M, Chiu K, Tessier-Cloutier B, Karnezis AN, Karsan A, Mungall A, Zhou C, Yip S, Tinker AV, Laskin J, Marra M, Jones SJM. Detection and Genomic Characterization of a mammary-like adenocarcinoma. Cold Spring Harbor Molecular Case Studies. PMID 28877932 DOI: 10.1101/mcs.a002170 |
0.303 |
|
| 2017 |
Wang Y, Chen SY, Karnezis AN, Colborne S, Santos ND, Lang JD, Hendricks WPD, Orlando KA, Yap D, Kommoss F, Bally MB, Morin GB, Trent JM, Weissman BE, Huntsman DG. The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcemic type. The Journal of Pathology. PMID 28444909 DOI: 10.1002/Path.4912 |
0.327 |
|
| 2017 |
Wang YK, Bashashati A, Anglesio MS, Cochrane DR, Grewal DS, Ha G, McPherson A, Horlings HM, Senz J, Prentice LM, Karnezis AN, Lai D, Aniba MR, Zhang AW, Shumansky K, et al. Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes. Nature Genetics. PMID 28436987 DOI: 10.1038/Ng.3849 |
0.394 |
|
| 2017 |
Talhouk A, McConechy MK, Leung S, Yang W, Lum A, Senz J, Boyd N, Pike J, Anglesio M, Kwon JS, Karnezis AN, Huntsman DG, Gilks CB, McAlpine JN. Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer. Cancer. PMID 28061006 DOI: 10.1002/cncr.30496 |
0.341 |
|
| 2017 |
Hoppe MM, Tan DS, Lim DG, Karnezis A, Huntsman D, Steel J, Liu X, Paul J, Lewsley L, Siddiqui N, Brown R, Jeyasekharan AD. Abstract B04: RAD51 expression as a biomarker of homologous recombination deficiency in ovarian cancer Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-B04 |
0.45 |
|
| 2016 |
Karnezis AN, Cho KR, Gilks CB, Pearce CL, Huntsman DG. The disparate origins of ovarian cancers: pathogenesis and prevention strategies. Nature Reviews. Cancer. PMID 27885265 DOI: 10.1038/Nrc.2016.113 |
0.345 |
|
| 2016 |
Coatham M, Li X, Karnezis AN, Hoang LN, Tessier-Cloutier B, Meng B, Soslow RA, Blake Gilks C, Huntsman DG, Stewart CJ, Postovit LM, Köbel M, Lee CH. Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27562491 DOI: 10.1038/modpathol.2016.156 |
0.305 |
|
| 2016 |
Wu R, Zhai Y, Kuick R, Karnezis AN, Garcia P, Naseem A, Hu TC, Fearon ER, Cho KR. Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse. The Journal of Pathology. PMID 27538791 DOI: 10.1002/Path.4783 |
0.312 |
|
| 2016 |
McPherson A, Roth A, Laks E, Masud T, Bashashati A, Zhang AW, Ha G, Biele J, Yap D, Wan A, Prentice LM, Khattra J, Smith MA, Nielsen CB, Mullaly SC, ... ... Karnezis A, et al. Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer. Nature Genetics. PMID 27182968 DOI: 10.1038/Ng.3573 |
0.415 |
|
| 2016 |
Anglesio MS, Wang YK, Maassen M, Horlings HM, Bashashati A, Senz J, Mackenzie R, Grewal DS, Li-Chang H, Karnezis AN, Sheffield BS, McConechy MK, Kommoss F, Taran FA, Staebler A, et al. Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality. Journal of the National Cancer Institute. 108. PMID 26832771 DOI: 10.1093/jnci/djv428 |
0.341 |
|
| 2016 |
Karnezis AN, Hoang LN, Coatham M, Ravn S, Almadani N, Cloutier B, Irving J, Meng B, Li X, Chow C, McAlpine J, Kuo KT, Mao TL, Djordjevic B, Soslow RA, et al. Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26743474 DOI: 10.1038/modpathol.2015.155 |
0.314 |
|
| 2016 |
Wang Y, Bashashati A, Anglesio MS, Cochrane D, Grewal D, Horlings H, Karnezis A, Mes-Masson A, Okamoto A, Yanagida S, Yanaihara N, Saito M, Gilks B, McAlpine J, Aparicio S, et al. Abstract LB-324: Genomic consequences of aberrant DNA repair stratify ovarian cancer histotypes Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-324 |
0.447 |
|
| 2015 |
Karnezis AN, Wang Y, Ramos P, Hendricks WP, Oliva E, D'Angelo E, Prat J, Nucci MR, Nielsen TO, Chow C, Leung S, Kommoss F, Kommoss S, Silva A, Ronnett BM, et al. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcemic type. The Journal of Pathology. PMID 26356327 DOI: 10.1002/Path.4633 |
0.309 |
|
| 2015 |
Talhouk A, McConechy MK, Leung S, Li-Chang HH, Kwon JS, Melnyk N, Yang W, Senz J, Boyd N, Karnezis AN, Huntsman DG, Gilks CB, McAlpine JN. A clinically applicable molecular-based classification for endometrial cancers. British Journal of Cancer. 113: 299-310. PMID 26172027 DOI: 10.1038/Bjc.2015.190 |
0.359 |
|
| 2015 |
George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, ... Karnezis AN, et al. Comprehensive genomic profiles of small cell lung cancer. Nature. 524: 47-53. PMID 26168399 DOI: 10.1038/Nature14664 |
0.369 |
|
| 2015 |
Mackenzie R, Kommoss S, Winterhoff BJ, Kipp BR, Garcia JJ, Voss J, Halling K, Karnezis A, Senz J, Yang W, Prigge ES, Reuschenbach M, Doeberitz MV, Gilks BC, Huntsman DG, et al. Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms. Bmc Cancer. 15: 415. PMID 25986173 DOI: 10.1186/S12885-015-1421-8 |
0.497 |
|
| 2015 |
Anglesio MS, Bashashati A, Wang YK, Senz J, Ha G, Yang W, Aniba MR, Prentice LM, Farahani H, Li Chang H, Karnezis AN, Marra MA, Yong PJ, Hirst M, Gilks B, et al. Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden. The Journal of Pathology. 236: 201-9. PMID 25692284 DOI: 10.1002/Path.4516 |
0.325 |
|
| 2014 |
Ramos P, Karnezis AN, Hendricks WP, Wang Y, Tembe W, Zismann VL, Legendre C, Liang WS, Russell ML, Craig DW, Farley JH, Monk BJ, Anthony SP, Sekulic A, Cunliffe HE, et al. Loss of the tumor suppressor SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Rare Diseases (Austin, Tex.). 2: e967148. PMID 26942101 DOI: 10.4161/2167549X.2014.967148 |
0.403 |
|
| 2014 |
Ramos P, Karnezis AN, Craig DW, Sekulic A, Russell ML, Hendricks WP, Corneveaux JJ, Barrett MT, Shumansky K, Yang Y, Shah SP, Prentice LM, Marra MA, Kiefer J, Zismann VL, et al. Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nature Genetics. 46: 427-9. PMID 24658001 DOI: 10.1038/Ng.2928 |
0.402 |
|
| 2014 |
Ramdzan ZM, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, Davoudi S, Hulea L, Yao L, Karnezis AN, Paquet M, Dankort D, Nepveu A. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. Plos Biology. 12: e1001807. PMID 24618719 DOI: 10.1371/Journal.Pbio.1001807 |
0.302 |
|
| 2014 |
Bashashati A, Anglesio M, Wang Y, Ha G, Senz J, Yang W, Kalloger S, Prentice L, Yanagida S, Salamanca C, Soukhatcheva G, Karnezis A, Chang H, Hirst M, Mes-Mason A, et al. Abstract LB-312: The somatic mutational landscape of ovarian clear cell carcinoma and its precursor lesions Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-312 |
0.422 |
|
| 2014 |
Ramos P, Karnezis A, Craig D, Sekulic A, Russell M, Hendricks W, Barrett M, Shumansky K, Yang Y, Shah S, Prentice L, Marra M, Kiefer J, Zismann V, McEachron T, et al. Abstract LB-202: The rare, highly malignant small cell carcinoma of the ovary displays common inactivating germline and somatic mutations in the tumor suppressor SMARCA4 Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-202 |
0.506 |
|
| 2013 |
Altman AD, Nelson GS, Ghatage P, McIntyre JB, Capper D, Chu P, Nation JG, Karnezis AN, Han G, Kalloger SE, Köbel M. The diagnostic utility of TP53 and CDKN2A to distinguish ovarian high-grade serous carcinoma from low-grade serous ovarian tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 1255-63. PMID 23558569 DOI: 10.1038/modpathol.2013.55 |
0.344 |
|
| 2013 |
Dumont N, Liu B, Defilippis RA, Chang H, Rabban JT, Karnezis AN, Tjoe JA, Marx J, Parvin B, Tlsty TD. Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia (New York, N.Y.). 15: 249-62. PMID 23479504 DOI: 10.1593/Neo.121950 |
0.305 |
|
| 2013 |
Soucek L, Whitfield JR, Sodir NM, Massó-Vallés D, Serrano E, Karnezis AN, Swigart LB, Evan GI. Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice. Genes & Development. 27: 504-13. PMID 23475959 DOI: 10.1101/Gad.205542.112 |
0.363 |
|
| 2012 |
Aysal A, Karnezis A, Medhi I, Grenert JP, Zaloudek CJ, Rabban JT. Ovarian endometrioid adenocarcinoma: incidence and clinical significance of the morphologic and immunohistochemical markers of mismatch repair protein defects and tumor microsatellite instability. The American Journal of Surgical Pathology. 36: 163-72. PMID 22189970 DOI: 10.1097/Pas.0B013E31823Bc434 |
0.45 |
|
| 2011 |
Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI, Soucek L. Endogenous Myc maintains the tumor microenvironment. Genes & Development. 25: 907-16. PMID 21478273 DOI: 10.1101/Gad.2038411 |
0.301 |
|
| 2011 |
Tihan T, Pekmezci M, Karnezis A. Neural stem cells and their role in the pathology and classification of central nervous system tumors. Tã¼Rk Patoloji Dergisi. 27: 1-11. PMID 21469420 DOI: 10.5146/Tjpath.2010.01040 |
0.325 |
|
| 2010 |
Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Research. 70: 3877-83. PMID 20406986 DOI: 10.1158/0008-5472.CAN-09-4228 |
0.308 |
|
| 2008 |
Murphy DJ, Junttila MR, Pouyet L, Karnezis A, Shchors K, Bui DA, Brown-Swigart L, Johnson L, Evan GI. Distinct thresholds govern Myc's biological output in vivo. Cancer Cell. 14: 447-57. PMID 19061836 DOI: 10.1016/J.Ccr.2008.10.018 |
0.386 |
|
| 2008 |
To MD, Wong CE, Karnezis AN, Del Rosario R, Di Lauro R, Balmain A. Kras regulatory elements and exon 4A determine mutation specificity in lung cancer. Nature Genetics. 40: 1240-4. PMID 18758463 DOI: 10.1038/Ng.211 |
0.32 |
|
| 1998 |
Engelman JA, Lee RJ, Karnezis A, Bearss DJ, Webster M, Siegel P, Muller WJ, Windle JJ, Pestell RG, Lisanti MP. Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. The Journal of Biological Chemistry. 273: 20448-55. PMID 9685399 DOI: 10.1074/Jbc.273.32.20448 |
0.474 |
|
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