Keith R. Yamamoto, PhD - Publications

Affiliations: 
Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Area:
glucocorticoid transcription
Website:
http://yamamotolab.ucsf.edu/keith.html

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ehmsen KT, Knuesel MT, Martinez D, Asahina M, Aridomi H, Yamamoto KR. Computational resources to define alleles and altered regulatory motifs at genomically edited candidate response elements. Nucleic Acids Research. PMID 34417596 DOI: 10.1093/nar/gkab700  0.349
2020 Wandler AM, Huang BJ, Craig JW, Hayes K, Yan H, Meyer LK, Scacchetti A, Monsalve G, Dail M, Li Q, Wong JC, Weinberg O, Hasserjian RP, Kogan SC, Jonsson P, ... Yamamoto K, et al. Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia. PMID 32066867 DOI: 10.1038/S41375-020-0748-6  0.355
2018 Monsalve GC, Yamamoto KR, Ward JD. A New Tool for Inducible Gene Expression in . Genetics. PMID 30504365 DOI: 10.1534/Genetics.118.301705  0.451
2017 Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, ... ... Yamamoto KR, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 1-5. PMID 28192788 DOI: 10.1038/Nature21076  0.357
2017 Weikum ER, Knuesel MT, Ortlund EA, Yamamoto KR. Glucocorticoid receptor control of transcription: precision and plasticity via allostery. Nature Reviews. Molecular Cell Biology. PMID 28053348 DOI: 10.1038/Nrm.2016.152  0.495
2016 Love MI, Huska MR, Jurk M, Schöpflin R, Starick SR, Schwahn K, Cooper SB, Yamamoto KR, Thomas-Chollier M, Vingron M, Meijsing SH. Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation. Nucleic Acids Research. PMID 27903902 DOI: 10.1093/Nar/Gkw1163  0.667
2016 Ratnappan R, Ward JD, Yamamoto KR, Ghazi A. Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations. Worm. 5: e1151609. PMID 27073739 DOI: 10.1080/21624054.2016.1151609  0.313
2016 Pack LR, Yamamoto KR, Fujimori DG. Opposing Chromatin Signals Direct and Regulate the Demethylase Activity of KDM4C. The Journal of Biological Chemistry. PMID 26747609 DOI: 10.1074/Jbc.M115.696864  0.381
2016 Wandler AM, Huang B, Scacchetti A, Craig J, Yan H, Monsalve G, Li Q, Dail M, Wong JC, Nakitandwe J, Weinberg O, Hasserjian RP, Kogan SC, Sampath D, Downing JR, ... Yamamoto K, et al. Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression Blood. 128: 753-753. DOI: 10.1182/Blood.V128.22.753.753  0.319
2015 Granner DK, Wang JC, Yamamoto KR. Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms. Advances in Experimental Medicine and Biology. 872: 3-31. PMID 26215988 DOI: 10.1007/978-1-4939-2895-8_1  0.671
2015 Chan LN, Chen Z, Braas D, Geng H, Hurtz C, Shojaee S, Cazzaniga V, Ng C, Ernst T, Hochhaus A, Kornblau SM, Cazzaniga G, Liu G, Milne T, Koeffler HP, ... ... Yamamoto KR, et al. B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling Blood. 126: 1255-1255. DOI: 10.1182/Blood.V126.23.1255.1255  0.322
2015 Granner DK, Wang JC, Yamamoto KR. Regulatory actions of glucocorticoid hormones: From organisms to mechanisms Advances in Experimental Medicine and Biology. 872: 3-31. DOI: 10.1007/978-1-4939-2895-8_1  0.625
2014 Ratnappan R, Amrit FR, Chen SW, Gill H, Holden K, Ward J, Yamamoto KR, Olsen CP, Ghazi A. Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans. Plos Genetics. 10: e1004829. PMID 25474470 DOI: 10.1371/Journal.Pgen.1004829  0.325
2014 Ward JD, Yamamoto KR, Asahina M. SUMO as a nuclear hormone receptor effector: New insights into combinatorial transcriptional regulation. Worm. 3: e29317. PMID 25254154 DOI: 10.4161/worm.29317  0.387
2014 Schiller BJ, Chodankar R, Watson LC, Stallcup MR, Yamamoto KR. Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes. Genome Biology. 15: 418. PMID 25085117 DOI: 10.1186/S13059-014-0418-Y  0.815
2014 Ward JD, Mullaney B, Schiller BJ, He le D, Petnic SE, Couillault C, Pujol N, Bernal TU, Van Gilst MR, Ashrafi K, Ewbank JJ, Yamamoto KR. Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses. Plos One. 9: e92552. PMID 24651852 DOI: 10.1371/Journal.Pone.0092552  0.771
2014 Chodankar R, Wu DY, Schiller BJ, Yamamoto KR, Stallcup MR. Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner Proceedings of the National Academy of Sciences of the United States of America. 111: 4007-4012. PMID 24591583 DOI: 10.1073/Pnas.1400522111  0.827
2013 Ward JD, Bojanala N, Bernal T, Ashrafi K, Asahina M, Yamamoto KR. Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development. Plos Genetics. 9: e1003992. PMID 24348269 DOI: 10.1371/Journal.Pgen.1003992  0.48
2013 Thomas-Chollier M, Watson LC, Cooper SB, Pufall MA, Liu JS, Borzym K, Vingron M, Yamamoto KR, Meijsing SH. A naturally occurring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms. Proceedings of the National Academy of Sciences of the United States of America. 110: 17826-31. PMID 24127590 DOI: 10.1073/Pnas.1316235110  0.76
2013 Watson LC, Kuchenbecker KM, Schiller BJ, Gross JD, Pufall MA, Yamamoto KR. The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals. Nature Structural & Molecular Biology. 20: 876-83. PMID 23728292 DOI: 10.1038/Nsmb.2595  0.817
2013 Chen SH, Masuno K, Cooper SB, Yamamoto KR. Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action. Proceedings of the National Academy of Sciences of the United States of America. 110: 1964-9. PMID 23307810 DOI: 10.1073/Pnas.1216108110  0.639
2011 Engel KB, Yamamoto KR. The glucocorticoid receptor and the coregulator Brm selectively modulate each other's occupancy and activity in a gene-specific manner. Molecular and Cellular Biology. 31: 3267-76. PMID 21646426 DOI: 10.1128/Mcb.05351-11  0.817
2011 Holdorf MM, Cooper SB, Yamamoto KR, Miranda JJL. Occupancy of chromatin organizers in the Epstein-Barr virus genome Virology. 415: 1-5. PMID 21550623 DOI: 10.1016/J.Virol.2011.04.004  0.591
2011 Ou CY, LaBonte MJ, Manegold PC, So AYL, Ianculescu I, Gerke DS, Yamamoto KR, Ladner RD, Kahn M, Kim JH, Stallcup MR. A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression Molecular Cancer Research. 9: 660-670. PMID 21478268 DOI: 10.1158/1541-7786.Mcr-10-0223  0.369
2011 Cvoro A, Yuan C, Paruthiyil S, Miller OH, Yamamoto KR, Leitman DC. Cross talk between glucocorticoid and estrogen receptors occurs at a subset of proinflammatory genes. Journal of Immunology (Baltimore, Md. : 1950). 186: 4354-60. PMID 21357268 DOI: 10.4049/Jimmunol.1002205  0.418
2011 Costa MJ, So AY, Kaasik K, Krueger KC, Pillsbury ML, Fu YH, Ptacek LJ, Yamamoto KR, Feldman BJ. Circadian rhythm gene period 3 is an inhibitor of the adipocyte cell fate. The Journal of Biological Chemistry. 286: 9063-70. PMID 21228270 DOI: 10.1074/Jbc.M110.164558  0.788
2011 Taubert S, Ward JD, Yamamoto KR. Nuclear hormone receptors in nematodes: Evolution and function Molecular and Cellular Endocrinology. 334: 49-55. PMID 20438802 DOI: 10.1016/J.Mce.2010.04.021  0.517
2010 Huff JT, Plocik AM, Guthrie C, Yamamoto KR. Reciprocal intronic and exonic histone modification regions in humans Nature Structural and Molecular Biology. 17: 1495-1499. PMID 21057525 DOI: 10.1038/Nsmb.1924  0.749
2010 DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, ... ... Yamamoto KR, et al. Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Research. 20: 1133-42. PMID 20508142 DOI: 10.1101/Gr.106773.110  0.346
2010 Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette-Stamm L, Yamamoto KR, Walhout AJM. Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network Molecular Systems Biology. 6. PMID 20461074 DOI: 10.1038/Msb.2010.23  0.377
2009 Beck IME, Berghe WV, Vermeulen L, Yamamoto KR, Haegeman G, De Bosscher K. Crosstalk in inflammation: The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases Endocrine Reviews. 30: 830-882. PMID 19890091 DOI: 10.1210/Er.2009-0013  0.403
2009 So AYL, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ. Glucocorticoid regulation of the circadian clock modulates glucose homeostasis Proceedings of the National Academy of Sciences of the United States of America. 106: 17582-17587. PMID 19805059 DOI: 10.1073/Pnas.0909733106  0.799
2009 Meijsing SH, Pufall MA, So AY, Bates DL, Chen L, Yamamoto KR. DNA binding site sequence directs glucocorticoid receptor structure and activity Science. 324: 407-410. PMID 19372434 DOI: 10.1126/Science.1164265  0.499
2009 Jones JO, Bolton EC, Huang Y, Feau C, Guy RK, Yamamoto KR, Hann B, Diamond MI. Non-competitive androgen receptor inhibition in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 7233-8. PMID 19363158 DOI: 10.1073/Pnas.0807282106  0.552
2008 Pantoja C, Huff JT, Yamamoto KR. Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro. Molecular Biology of the Cell. 19: 4032-41. PMID 18653467 DOI: 10.1091/Mbc.E08-04-0420  0.76
2008 Taubert S, Hansen M, Van Gilst MR, Cooper SB, Yamamoto KR. The Mediator subunit MDT-15 confers metabolic adaptation to ingested material. Plos Genetics. 4: e1000021. PMID 18454197 DOI: 10.1371/Journal.Pgen.1000021  0.631
2008 So AY, Cooper SB, Feldman BJ, Manuchehri M, Yamamoto KR. Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes. Proceedings of the National Academy of Sciences of the United States of America. 105: 5745-9. PMID 18408151 DOI: 10.1073/Pnas.0801551105  0.641
2007 Woodruff PG, Boushey HA, Dolganov GM, Barker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu SS, Dao-Pick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proceedings of the National Academy of Sciences of the United States of America. 104: 15858-63. PMID 17898169 DOI: 10.1073/Pnas.0707413104  0.752
2007 Bolton EC, So AY, Chaivorapol C, Haqq CM, Li H, Yamamoto KR. Cell- and gene-specific regulation of primary target genes by the androgen receptor. Genes & Development. 21: 2005-17. PMID 17699749 DOI: 10.1101/Gad.1564207  0.467
2007 So AY, Chaivorapol C, Bolton EC, Li H, Yamamoto KR. Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor. Plos Genetics. 3: e94. PMID 17559307 DOI: 10.1371/Journal.Pgen.0030094  0.488
2007 Ricketson D, Hostick U, Fang L, Yamamoto KR, Darimont BD. A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90. Journal of Molecular Biology. 368: 729-41. PMID 17367809 DOI: 10.1016/J.Jmb.2007.02.057  0.459
2007 Meijsing SH, Elbi C, Luecke HF, Hager GL, Yamamoto KR. The ligand binding domain controls glucocorticoid receptor dynamics independent of ligand release. Molecular and Cellular Biology. 27: 2442-51. PMID 17261597 DOI: 10.1128/Mcb.01570-06  0.43
2006 Taubert S, Van Gilst MR, Hansen M, Yamamoto KR. A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans. Genes & Development. 20: 1137-49. PMID 16651656 DOI: 10.1101/Gad.1395406  0.412
2006 Wang JC, Shah N, Pantoja C, Meijsing SH, Ho JD, Scanlan TS, Yamamoto KR. Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity Genes and Development. 20: 689-699. PMID 16543221 DOI: 10.1101/Gad.1400506  0.824
2005 Van Gilst MR, Hadjivassiliou H, Yamamoto KR. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proceedings of the National Academy of Sciences of the United States of America. 102: 13496-501. PMID 16157872 DOI: 10.1073/Pnas.0506234102  0.365
2005 Luecke HF, Yamamoto KR. The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression. Genes & Development. 19: 1116-27. PMID 15879558 DOI: 10.1101/Gad.1297105  0.393
2005 Van Gilst MR, Hadjivassiliou H, Jolly A, Yamamoto KR. Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans. Plos Biology. 3: e53. PMID 15719061 DOI: 10.1371/Journal.Pbio.0030053  0.41
2005 Shostak Y, Yamamoto KR. Overlapping but separable determinants of DNA binding and nuclear localization map to the C-terminal end of the Caenorhabditis elegans DAF-12 DNA binding domain. The Journal of Biological Chemistry. 280: 6554-60. PMID 15611047 DOI: 10.1074/Jbc.M412928200  0.803
2004 Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq C, Yamamoto KR. Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes. Proceedings of the National Academy of Sciences of the United States of America. 101: 15603-8. PMID 15501915 DOI: 10.1073/Pnas.0407008101  0.655
2004 Shostak Y, Van Gilst MR, Antebi A, Yamamoto KR. Identification of C. elegans DAF-12-binding sites, response elements, and target genes. Genes & Development. 18: 2529-44. PMID 15489294 DOI: 10.1101/Gad.1218504  0.816
2004 Wang JC, Walker A, Blackwell TK, Yamamoto KR. The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis. The Journal of Biological Chemistry. 279: 29270-7. PMID 15073178 DOI: 10.1074/Jbc.M401242200  0.612
2004 Freedman ND, Yamamoto KR. Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor. Molecular Biology of the Cell. 15: 2276-86. PMID 15004228 DOI: 10.1091/Mbc.E03-11-0839  0.577
2004 Tee MK, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ, Yamamoto KR, Leitman DC. Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Molecular Biology of the Cell. 15: 1262-72. PMID 14699072 DOI: 10.1091/Mbc.E03-06-0360  0.457
2003 Rogatsky I, Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq CM, Darimont BD, Garabedian MJ, Yamamoto KR. Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 13845-50. PMID 14617768 DOI: 10.1073/Pnas.2336092100  0.758
2002 Rogatsky I, Luecke HF, Leitman DC, Yamamoto KR. Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proceedings of the National Academy of Sciences of the United States of America. 99: 16701-6. PMID 12481024 DOI: 10.1073/Pnas.262671599  0.477
2002 Freeman BC, Yamamoto KR. Disassembly of transcriptional regulatory complexes by molecular chaperones. Science (New York, N.Y.). 296: 2232-5. PMID 12077419 DOI: 10.1126/Science.1073051  0.442
2001 Rogatsky I, Zarember KA, Yamamoto KR. Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. The Embo Journal. 20: 6071-83. PMID 11689447 DOI: 10.1093/Emboj/20.21.6071  0.51
2000 Nissen RM, Yamamoto KR. The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes & Development. 14: 2314-29. PMID 10995388 DOI: 10.1101/Gad.827900  0.461
2000 van Tilborg MA, Lefstin JA, Kruiskamp M, Teuben J, Boelens R, Yamamoto KR, Kaptein R. Mutations in the glucocorticoid receptor DNA-binding domain mimic an allosteric effect of DNA. Journal of Molecular Biology. 301: 947-58. PMID 10966797 DOI: 10.1006/Jmbi.2000.4001  0.406
2000 Jamieson CA, Yamamoto KR. Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cell receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 97: 7319-24. PMID 10860997 DOI: 10.1073/Pnas.97.13.7319  0.349
2000 Freeman BC, Felts SJ, Toft DO, Yamamoto KR. The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies. Genes & Development. 14: 422-34. PMID 10691735 DOI: 10.1101/Gad.14.4.422  0.382
2000 Diamond MI, Robinson MR, Yamamoto KR. Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 657-61. PMID 10639135 DOI: 10.1073/Pnas.97.2.657  0.451
1999 Alberts BM, Ayala FJ, Botstein D, Frank E, Holmes EW, Lee RD, Macagno ER, Marrack P, Oparil S, Orkin SH, Rubenstein AH, Slayman CW, Sparling PF, Squire LR, von Hippel PH, ... Yamamoto KR, et al. Proposed changes for NIH's Center for Scientific Review. Panel on Scientific Boundaries for Review. Center for Scientific Review Advisory Committee, National Institutes of Health. Science (New York, N.Y.). 285: 666-7. PMID 10454921 DOI: 10.1126/Science.285.5428.666  0.457
1999 Hong H, Darimont BD, Ma H, Yang L, Yamamoto KR, Stallcup MR. An additional region of coactivator GRIP1 required for interaction with the hormone-binding domains of a subset of nuclear receptors. The Journal of Biological Chemistry. 274: 3496-502. PMID 9920895 DOI: 10.1074/Jbc.274.6.3496  0.362
1998 Yamamoto KR, Darimont BD, Wagner RL, Iñiguez-Lluhí JA. Building transcriptional regulatory complexes: signals and surfaces. Cold Spring Harbor Symposia On Quantitative Biology. 63: 587-98. PMID 10384324 DOI: 10.1101/Sqb.1998.63.587  0.321
1998 Darimont BD, Wagner RL, Apriletti JW, Stallcup MR, Kushner PJ, Baxter JD, Fletterick RJ, Yamamoto KR. Structure and specificity of nuclear receptor-coactivator interactions. Genes & Development. 12: 3343-56. PMID 9808622 DOI: 10.1101/Gad.12.21.3343  0.62
1998 Pearce D, Matsui W, Miner JN, Yamamoto KR. Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites. The Journal of Biological Chemistry. 273: 30081-5. PMID 9804760 DOI: 10.1074/Jbc.273.46.30081  0.432
1998 Lefstin JA, Yamamoto KR. Allosteric effects of DNA on transcriptional regulators. Nature. 392: 885-8. PMID 9582068 DOI: 10.1038/31860  0.474
1997 Lichtarge O, Yamamoto KR, Cohen FE. Identification of functional surfaces of the zinc binding domains of intracellular receptors. Journal of Molecular Biology. 274: 325-37. PMID 9405143 DOI: 10.1006/Jmbi.1997.1395  0.485
1997 Krstic MD, Rogatsky I, Yamamoto KR, Garabedian MJ. Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Molecular and Cellular Biology. 17: 3947-54. PMID 9199329 DOI: 10.1128/Mcb.17.7.3947  0.645
1997 Iñiguez-Lluhí JA, Lou DY, Yamamoto KR. Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus. The Journal of Biological Chemistry. 272: 4149-56. PMID 9020127 DOI: 10.1074/Jbc.272.7.4149  0.416
1996 Miller ME, Cairns BR, Levinson RS, Yamamoto KR, Engel DA, Smith MM. Adenovirus E1A specifically blocks SWI/SNF-dependent transcriptional activation. Molecular and Cellular Biology. 16: 5737-43. PMID 8816487 DOI: 10.1128/Mcb.16.10.5737  0.449
1996 Cairns BR, Levinson RS, Yamamoto KR, Kornberg RD. Essential role of Swp73p in the function of yeast Swi/Snf complex. Genes & Development. 10: 2131-44. PMID 8804308 DOI: 10.1101/Gad.10.17.2131  0.444
1996 Xu M, Chakraborti PK, Garabedian MJ, Yamamoto KR, Simons SS. Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains. The Journal of Biological Chemistry. 271: 21430-8. PMID 8702925 DOI: 10.1074/Jbc.271.35.21430  0.646
1996 Starr DB, Matsui W, Thomas JR, Yamamoto KR. Intracellular receptors use a common mechanism to interpret signaling information at response elements. Genes & Development. 10: 1271-83. PMID 8675013 DOI: 10.1101/Gad.10.10.1271  0.461
1996 Kralli A, Yamamoto KR. An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones. The Journal of Biological Chemistry. 271: 17152-6. PMID 8663352 DOI: 10.1074/Jbc.271.29.17152  0.48
1995 Holley SJ, Yamamoto KR. A role for Hsp90 in retinoid receptor signal transduction. Molecular Biology of the Cell. 6: 1833-42. PMID 8590809 DOI: 10.1091/Mbc.6.12.1833  0.459
1995 Vivanco MD, Johnson R, Galante PE, Hanahan D, Yamamoto KR. A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development. The Embo Journal. 14: 2217-28. PMID 7774580 DOI: 10.1002/J.1460-2075.1995.Tb07216.X  0.419
1995 Kralli A, Bohen SP, Yamamoto KR. LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones. Proceedings of the National Academy of Sciences of the United States of America. 92: 4701-5. PMID 7753868 DOI: 10.1073/Pnas.92.10.4701  0.436
1995 van Tilborg MA, Bonvin AM, Hård K, Davis AL, Maler B, Boelens R, Yamamoto KR, Kaptein R. Structure refinement of the glucocorticoid receptor-DNA binding domain from NMR data by relaxation matrix calculations. Journal of Molecular Biology. 247: 689-700. PMID 7723024 DOI: 10.1016/S0022-2836(05)80148-2  0.354
1994 La Baer J, Yamamoto KR. Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region. Journal of Molecular Biology. 239: 664-88. PMID 8014988 DOI: 10.1006/Jmbi.1994.1405  0.44
1994 Lefstin JA, Thomas JR, Yamamoto KR. Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions. Genes & Development. 8: 2842-56. PMID 7995522 DOI: 10.1101/Gad.8.23.2842  0.499
1993 Scherrer LC, Picard D, Massa E, Harmon JM, Simons SS, Yamamoto KR, Pratt WB. Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90. Biochemistry. 32: 5381-6. PMID 8499442 DOI: 10.1021/Bi00071A013  0.613
1993 Imai E, Miner JN, Mitchell JA, Yamamoto KR, Granner DK. Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. The Journal of Biological Chemistry. 268: 5353-6. PMID 8449898  0.618
1993 Pearce D, Yamamoto KR. Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element. Science (New York, N.Y.). 259: 1161-5. PMID 8382376 DOI: 10.1126/Science.8382376  0.474
1993 Bohen SP, Yamamoto KR. Isolation of Hsp90 mutants by screening for decreased steroid receptor function. Proceedings of the National Academy of Sciences of the United States of America. 90: 11424-8. PMID 8248264 DOI: 10.1073/Pnas.90.23.11424  0.43
1992 Amero SA, Kretsinger RH, Moncrief ND, Yamamoto KR, Pearson WR. The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors. Molecular Endocrinology (Baltimore, Md.). 6: 3-7. PMID 1738368 DOI: 10.1210/Mend.6.1.1738368  0.519
1992 Chakraborti PK, Garabedian MJ, Yamamoto KR, Simons SS. Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors. The Journal of Biological Chemistry. 267: 11366-73. PMID 1597467  0.622
1992 Garabedian MJ, Yamamoto KR. Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast. Molecular Biology of the Cell. 3: 1245-57. PMID 1457829 DOI: 10.1091/Mbc.3.11.1245  0.665
1992 Yoshinaga SK, Peterson CL, Herskowitz I, Yamamoto KR. Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors. Science (New York, N.Y.). 258: 1598-604. PMID 1360703 DOI: 10.1126/Science.1360703  0.482
1992 Miner JN, Yamamoto KR. The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element. Genes & Development. 6: 2491-501. PMID 1340464 DOI: 10.1101/Gad.6.12B.2491  0.458
1992 Yamamoto KR, Pearce D, Thomas J, Miner JN. 43 Combinatorial Regulation at a Mammalian Composite Response Element Cold Spring Harbor Monograph Archive. 1169-1192. DOI: 10.1101/087969425.22B.1169  0.43
1991 Schena M, Picard D, Yamamoto KR. Vectors for constitutive and inducible gene expression in yeast. Methods in Enzymology. 194: 389-98. PMID 2005799 DOI: 10.1016/0076-6879(91)94029-C  0.597
1991 Chakraborti PK, Garabedian MJ, Yamamoto KR, Simons SS. Creation of "super" glucocorticoid receptors by point mutations in the steroid binding domain. The Journal of Biological Chemistry. 266: 22075-8. PMID 1939229  0.62
1991 Kellenbach E, Maler BA, Yamamoto KR, Boelens R, Kaptein R. Identification of the metal coordinating residues in the DNA binding domain of the glucocorticoid receptor by 113Cd-1H heteronuclear NMR spectroscopy. Febs Letters. 291: 367-70. PMID 1936288 DOI: 10.1016/0014-5793(91)81322-Y  0.335
1991 Luisi BF, Xu WX, Otwinowski Z, Freedman LP, Yamamoto KR, Sigler PB. Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature. 352: 497-505. PMID 1865905 DOI: 10.1038/352497A0  0.386
1991 Kellenbach E, Härd T, Boelens R, Dahlman K, Carlstedt-Duke J, Gustafsson JA, van der Marel GA, van Boom JH, Maler B, Yamamoto KR. Photo-CIDNP study of the interaction between the glucocorticoid receptor DNA-binding domain and glucocorticoid response elements. Journal of Biomolecular Nmr. 1: 105-10. PMID 1841686 DOI: 10.1007/Bf01874574  0.397
1991 Miner JN, Yamamoto KR. Regulatory crosstalk at composite response elements. Trends in Biochemical Sciences. 16: 423-6. PMID 1776172 DOI: 10.1016/0968-0004(91)90168-U  0.348
1991 Remerowski ML, Kellenbach E, Boelens R, van der Marel GA, van Boom JH, Maler BA, Yamamoto KR, Kaptein R. 1H NMR studies of DNA recognition by the glucocorticoid receptor: complex of the DNA binding domain with a half-site response element. Biochemistry. 30: 11620-4. PMID 1751485 DOI: 10.1021/Bi00114A003  0.367
1991 Yoshinaga SK, Yamamoto KR. Signaling and regulation by a mammalian glucocorticoid receptor in Drosophila cells. Molecular Endocrinology (Baltimore, Md.). 5: 844-53. PMID 1681427 DOI: 10.1210/Mend-5-6-844  0.501
1990 Howard KJ, Holley SJ, Yamamoto KR, Distelhorst CW. Mapping the HSP90 binding region of the glucocorticoid receptor. The Journal of Biological Chemistry. 265: 11928-35. PMID 2365707  0.314
1990 Debs RJ, Freedman LP, Edmunds S, Gaensler KL, Düzgünes N, Yamamoto KR. Regulation of gene expression in vivo by liposome-mediated delivery of a purified transcription factor. The Journal of Biological Chemistry. 265: 10189-92. PMID 2354996  0.33
1990 Picard D, Khursheed B, Garabedian MJ, Fortin MG, Lindquist S, Yamamoto KR. Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature. 348: 166-8. PMID 2234079 DOI: 10.1038/348166A0  0.729
1990 Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR. Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science (New York, N.Y.). 249: 1266-72. PMID 2119054 DOI: 10.1126/Science.2119054  0.428
1990 Härd T, Kellenbach E, Boelens R, Maler BA, Dahlman K, Freedman LP, Carlstedt-Duke J, Yamamoto KR, Gustafsson JA, Kaptein R. Solution structure of the glucocorticoid receptor DNA-binding domain. Science (New York, N.Y.). 249: 157-60. PMID 2115209 DOI: 10.1126/Science.2115209  0.382
1990 Picard D, Schena M, Yamamoto KR. An inducible expression vector for both fission and budding yeast. Gene. 86: 257-61. PMID 2108906 DOI: 10.1016/0378-1119(90)90287-2  0.615
1990 Picard D, Kumar V, Chambon P, Yamamoto KR. Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors. Cell Regulation. 1: 291-9. PMID 2100202 DOI: 10.1091/Mbc.1.3.291  0.636
1990 Privalsky ML, Sharif M, Yamamoto KR. The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast. Cell. 63: 1277-86. PMID 1979758 DOI: 10.1016/0092-8674(90)90423-C  0.469
1989 Eilers M, Picard D, Yamamoto KR, Bishop JM. Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature. 340: 66-8. PMID 2662015 DOI: 10.1038/340066a0  0.608
1989 Schena M, Freedman LP, Yamamoto KR. Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities. Genes & Development. 3: 1590-601. PMID 2515114 DOI: 10.1101/Gad.3.10.1590  0.508
1989 Freedman LP, Yoshinaga SK, Vanderbilt JN, Yamamoto KR. In vitro transcription enhancement by purified derivatives of the glucocorticoid receptor. Science (New York, N.Y.). 245: 298-301. PMID 2473529 DOI: 10.1126/Science.2473529  0.52
1988 Sakai DD, Helms S, Carlstedt-Duke J, Gustafsson JA, Rottman FM, Yamamoto KR. Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. Genes & Development. 2: 1144-54. PMID 3192076 DOI: 10.1101/Gad.2.9.1144  0.528
1988 Yamamoto KR, Godowski PJ, Picard D. Ligand-regulated nonspecific inactivation of receptor function: A versatile mechanism for signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 803-811. PMID 3076098 DOI: 10.1101/Sqb.1988.053.01.091  0.584
1988 Schena M, Yamamoto KR. Mammalian glucocorticoid receptor derivatives enhance transcription in yeast. Science (New York, N.Y.). 241: 965-7. PMID 3043665 DOI: 10.1126/SCIENCE.3043665  0.442
1988 Godowski PJ, Picard D, Yamamoto KR. Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins Science. 241: 812-816. PMID 3043662 DOI: 10.1126/Science.3043662  0.675
1988 Freedman LP, Luisi BF, Korszun ZR, Basavappa R, Sigler PB, Yamamoto KR. The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain. Nature. 334: 543-6. PMID 3043231 DOI: 10.1038/334543A0  0.476
1988 Picard D, Salser SJ, Yamamoto KR. A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor. Cell. 54: 1073-80. PMID 2843290 DOI: 10.1016/0092-8674(88)90122-5  0.666
1988 Vanderbilt JN, Miesfeld R, Maler BA, Yamamoto KR. Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity. Molecular Endocrinology (Baltimore, Md.). 1: 68-74. PMID 2842660 DOI: 10.1210/Mend-1-1-68  0.756
1987 Godowski PJ, Rusconi S, Miesfeld R, Yamamoto KR. Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement. Nature. 325: 365-368. PMID 3808033 DOI: 10.1038/325365A0  0.724
1987 Miesfeld R, Godowski PJ, Maler BA, Yamamoto KR. Glucocorticoid receptor mutants that define a small region sufficient for enhancer activation. Science (New York, N.Y.). 236: 423-7. PMID 3563519 DOI: 10.1126/Science.3563519  0.738
1987 DeFranco D, Yamamoto KR. Two different factors act separately or together to specify functionally distinct activities at a single transcriptional enhancer. Molecular and Cellular Biology. 6: 993-1001. PMID 3023887 DOI: 10.1128/MCB.6.4.993  0.397
1987 Picard D, Yamamoto KR. Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. The Embo Journal. 6: 3333-3340. DOI: 10.1002/J.1460-2075.1987.Tb02654.X  0.476
1987 Rusconi S, Yamamoto KR. Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. The Embo Journal. 6: 1309-1315. DOI: 10.1002/J.1460-2075.1987.Tb02369.X  0.48
1986 Yamamoto KR. Steroid receptor regulated transcription of specific genes and gene networks. Annual Review of Genetics. 19: 209-52. PMID 3909942 DOI: 10.1146/ANNUREV.GE.19.120185.001233  0.342
1986 Miesfeld R, Rusconi S, Godowski PJ, Maler BA, Okret S, Wikström AC, Gustafsson JA, Yamamoto KR. Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA. Cell. 46: 389-99. PMID 3755378 DOI: 10.1016/0092-8674(86)90659-8  0.74
1986 Firestone GL, John NJ, Yamamoto KR. Glucocorticoid-regulated glycoprotein maturation in wild-type and mutant rat cell lines. The Journal of Cell Biology. 103: 2323-31. PMID 3023398 DOI: 10.1083/Jcb.103.6.2323  0.595
1985 Jones KA, Yamamoto KR, Tjian R. Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro Cell. 42: 559-572. PMID 2992804 DOI: 10.1016/0092-8674(85)90113-8  0.446
1984 Miesfeld R, Okret S, Wikström AC, Wrange Ö, Gustafsson JÅ, Yamamoto KR. Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells Nature. 312: 779-781. PMID 6549049 DOI: 10.1038/312779A0  0.747
1984 Zaret KS, Yamamoto KR. Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element Cell. 38: 29-38. PMID 6088072 DOI: 10.1016/0092-8674(84)90523-3  0.502
1983 Payvar F, DeFranco D, Firestone GL, Edgar B, Wrange O, Okret S, Gustafsson JA, Yamamoto KR. Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region. Cell. 35: 381-92. PMID 6317184 DOI: 10.1016/0092-8674(83)90171-X  0.679
1983 Yamamoto KR, Payvar F, Firestone GL, Maler BA, Wrange O, Carlstedt-Duke J, Gustafsson JA, Chandler VL. Biological activity of cloned mammary tumor virus DNA fragments that bind purified glucocorticoid receptor protein in vitro. Cold Spring Harbor Symposia On Quantitative Biology. 47: 977-84. PMID 6305596 DOI: 10.1101/Sqb.1983.047.01.111  0.632
1983 Ucker DS, Firestone GL, Yamamoto KR. Glucocorticoids and chromosomal position modulate murine mammary tumor virus transcription by affecting efficiency of promoter utilization. Molecular and Cellular Biology. 3: 551-61. PMID 6304497 DOI: 10.1128/Mcb.3.4.551  0.609
1983 Firestone GL, Yamamoto KR. Two classes of mutant mammary tumor virus-infected HTC cell with defects in glucocorticoid-regulated gene expression. Molecular and Cellular Biology. 3: 149-60. PMID 6300655  0.611
1983 Baumann H, Firestone GL, Burgess TL, Gross KW, Yamamoto KR, Held WA. Dexamethasone regulation of alpha 1-acid glycoprotein and other acute phase reactants in rat liver and hepatoma cells. The Journal of Biological Chemistry. 258: 563-70. PMID 6184374  0.49
1982 Payvar F, Firestone GL, Ross SR, Chandler VL, Wrange O, Carlstedt-Duke J, Gustafsson JA, Yamamoto KR. Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA. Journal of Cellular Biochemistry. 19: 241-7. PMID 6296168 DOI: 10.1002/Jcb.240190305  0.676
1982 Firestone GL, Payvar F, Yamamoto KR. Glucocorticoid regulation of protein processing and compartmentalization. Nature. 300: 221-5. PMID 6292722 DOI: 10.1038/300221A0  0.609
1982 Feinstein SC, Ross SR, Yamamoto KR. Chromosomal position effects determine transcriptional potential of integrated mammary tumor virus DNA Journal of Molecular Biology. 156: 549-565. PMID 6288960 DOI: 10.1016/0022-2836(82)90266-2  0.406
1982 Payvar F, Wrange O, Carlstedt-Duke J, Okret S, Gustafsson JA, Yamamoto KR. Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo. Proceedings of the National Academy of Sciences of the United States of America. 78: 6628-32. PMID 6273877 DOI: 10.1073/Pnas.78.11.6628  0.496
1981 Yamamoto KR, Chandler VL, Ross SR, Ucker DS, Ring JC, Feinstein SC. Integration and activity of mammary tumor virus genes: regulation by hormone receptors and chromosomal position. Cold Spring Harbor Symposia On Quantitative Biology. 45: 687-97. PMID 6266760 DOI: 10.1101/Sqb.1981.045.01.086  0.389
1979 Sibley CH, Yamamoto KR. Mouse lymphoma cells: mechanisms of resistance to glucocorticoids Monographs On Endocrinology. 12: 357-376. PMID 492175  0.617
1979 Ringold GM, Shank PR, Varmus HE, Ring J, Yamamoto KR. Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells Proceedings of the National Academy of Sciences of the United States of America. 76: 665-669. PMID 218215 DOI: 10.1073/Pnas.76.2.665  0.321
1978 Ringold GM, Cohen JC, Ring J, Shank PR, Varmus HE, Yamamoto KR. Mouse mammary tumor virus genes: Regulation of expression by glucocorticoids and structural analysis with restriction endonucleases Journal of Toxicology and Environmental Health. 4: 457-470. PMID 207882 DOI: 10.1080/15287397809529671  0.354
1978 Yamamoto KR, Ivarie RD, Ring J, Ringold GM, Stallcup MR. CHAPTER 9 – Integrated Mammary Tumor Virus Genes: Transcriptional Regulation by Glucocorticoids and Specific Effects on Host Gene Expression Biochemical Actions of Hormones. 373-395. DOI: 10.1016/B978-0-12-452805-5.50015-6  0.38
1977 Yamamoto KR, Stallcup MR, Ring J, Ringold GM. Mammary tumor virus DNA: A glucocorticoid responsive transposable element Cold Spring Harbor Symposia On Quantitative Biology. 42: 625-638. PMID 28200 DOI: 10.1101/Sqb.1978.042.01.065  0.464
1976 Yamamoto KR, Alberts BM. Steroid receptors: elements for modulation of eukaryotic transcription. Annual Review of Biochemistry. 45: 721-46. PMID 183602 DOI: 10.1146/annurev.bi.45.070176.003445  0.577
1976 Yamamoto KR, Gehring U, Stampfer MR, Sibley CH. Genetic approaches to steroid hormone action Recent Progress in Hormone Research. 32: 3-32. PMID 183244  0.494
1975 Ringold GM, Yamamoto KR, Tomkins GM, Bishop M, Varmus HE. Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action. Cell. 6: 299-305. PMID 212202 DOI: 10.1016/0092-8674(75)90181-6  0.555
1975 Gehring U, Yamamoto K, Tomkins G. 1. Complementation analysis of steroid hormone action Journal of Steroid Biochemistry. 6: iii. DOI: 10.1016/0022-4731(75)90218-6  0.502
1974 Yamamoto KR, Alberts B. On the specificity of the binding of the estradiol receptor protein to deoxyribonucleic acid. The Journal of Biological Chemistry. 249: 7076-86. PMID 4373456  0.546
1974 Yamamoto KR, Stampfer MR, Tomkins GM. Receptors from glucocorticoid-sensitive lymphoma cells and two clases of insensitive clones: physical and DNA-binding properties. Proceedings of the National Academy of Sciences of the United States of America. 71: 3901-5. PMID 4372597 DOI: 10.1073/Pnas.71.10.3901  0.659
1972 Yamamoto KR, Alberts BM. In vitro conversion of estradiol-receptor protein to its nuclear form: dependence on hormone and DNA. Proceedings of the National Academy of Sciences of the United States of America. 69: 2105-9. PMID 4506080  0.579
1970 Yamamoto KR, Alberts BM, Benzinger R, Lawhorne L, Treiber G. Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification. Virology. 40: 734-44. PMID 4908735 DOI: 10.1016/0042-6822(70)90218-7  0.381
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