Gary S Stein - Publications

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Dashti P, Lewallen EA, Gordon JAR, Montecino MA, Davie JR, Stein GS, van Leeuwen JPTM, van der Eerden BCJ, van Wijnen AJ. Epigenetic regulators controlling osteogenic lineage commitment and bone formation. Bone. 117043. PMID 38341164 DOI: 10.1016/j.bone.2024.117043  0.36
2023 Tracy KM, Prior S, Trowbridge WT, Boyd JR, Ghule PN, Frietze S, Stein JL, Stein GS, Lian JB. Bromodomain Proteins Epigenetically Regulate the Mitotically Associated lncRNA MANCR in Triple Negative Breast Cancer Cells. Critical Reviews in Eukaryotic Gene Expression. 34: 61-71. PMID 38073442 DOI: 10.1615/CritRevEukaryotGeneExpr.2023050109  0.307
2023 Gordon JAR, Tye CE, Banerjee B, Ghule PN, van Wijnen AJ, Kabala FS, Page NA, Falcone MM, Stein JL, Stein GS, Lian JB. LINC01638 sustains human mesenchymal stem cell self-renewal and competency for osteogenic cell fate. Scientific Reports. 13: 20314. PMID 37985890 DOI: 10.1038/s41598-023-46202-z  0.36
2023 Gordon J, Tye CE, Banerjee B, Ghule PN, Wijnen AJ, Kabala FS, Page NA, Falcone MM, Stein JL, Stein GS, Lian JB. LINC01638 Sustains Human Mesenchymal Stem Cell Self-Renewal and Competency for Osteogenic Cell Fate. Research Square. PMID 37693373 DOI: 10.21203/rs.3.rs-3210911/v1  0.362
2023 Dashti P, Lewallen EA, Gordon JAR, Montecino MA, van Leeuwen JPTM, Stein GS, van der Eerden BCJ, Davie JR, van Wijnen AJ. Protein arginine methyltransferases PRMT1, PRMT4/CARM1 and PRMT5 have distinct functions in control of osteoblast differentiation. Bone Reports. 19: 101704. PMID 37593409 DOI: 10.1016/j.bonr.2023.101704  0.369
2023 Ghule PN, Boyd JR, Kabala F, Fritz AJ, Bouffard NA, Gao C, Bright K, Macfarlane J, Seward DJ, Pegoraro G, Misteli T, Lian JB, Frietze S, Stein JL, van Wijnen AJ, ... Stein GS, et al. Spatiotemporal higher-order chromatin landscape of human histone gene clusters at histone locus bodies during the cell cycle in breast cancer progression. Gene. 872: 147441. PMID 37094694 DOI: 10.1016/j.gene.2023.147441  0.317
2023 Fritz AJ, Ghule PN, Toor R, Dillac L, Perelman J, Boyd J, Lian JB, Gordon JAR, Frietze S, Van Wijnen A, Stein JL, Stein GS. Spatiotemporal Epigenetic Control of the Histone Gene Chromatin Landscape during the Cell Cycle. Critical Reviews in Eukaryotic Gene Expression. 33: 85-97. PMID 37017672 DOI: 10.1615/CritRevEukaryotGeneExpr.2022046190  0.362
2022 El Dika M, Fritz AJ, Toor RH, Rodriguez PD, Foley SJ, Ullah R, Nie D, Banerjee B, Lohese D, Tracy KM, Glass KC, Frietze S, Ghule PN, Heath JL, Imbalzano AN, ... ... Stein GS, et al. Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Fidelity of Mechanisms Governing the Cell Cycle. Results and Problems in Cell Differentiation. 70: 375-396. PMID 36348115 DOI: 10.1007/978-3-031-06573-6_13  0.314
2022 Fritz AJ, El Dika M, Toor RH, Rodriguez PD, Foley SJ, Ullah R, Nie D, Banerjee B, Lohese D, Tracy KM, Glass KC, Frietze S, Ghule PN, Heath JL, Imbalzano AN, ... ... Stein GS, et al. Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Cell and Tissue Structure, Function, and Phenotype. Results and Problems in Cell Differentiation. 70: 339-373. PMID 36348114 DOI: 10.1007/978-3-031-06573-6_12  0.305
2022 Dashti P, van de Peppel J, Thaler R, Paradise CR, Stein GS, Montecino MA, van Leeuwen JPTM, van der Eerden BJ, Dudakovic A, van Wijnen AJ. The lysine methyltransferases SET and MYND domain containing 2 (Smyd2) and Enhancer of Zeste 2 (Ezh2) co-regulate osteoblast proliferation and mineralization. Gene. 851: 146928. PMID 36191822 DOI: 10.1016/j.gene.2022.146928  0.364
2022 Messier TL, Boyd JR, Gordon JAR, Tye CE, Page NA, Toor RH, Zaidi SK, Komm BS, Frietze S, Stein JL, Lian JB, Stein GS. Epigenetic and transcriptome responsiveness to ER modulation by tissue selective estrogen complexes in breast epithelial and breast cancer cells. Plos One. 17: e0271725. PMID 35862394 DOI: 10.1371/journal.pone.0271725  0.303
2022 Tye CE, Ghule PN, Gordon JAR, Kabala FS, Page NA, Falcone MM, Tracy KM, van Wijnen AJ, Stein JL, Lian JB, Stein GS. LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment. Scientific Reports. 12: 7770. PMID 35546168 DOI: 10.1038/s41598-022-11814-4  0.337
2021 Bighetti-Trevisan RL, Almeida LO, Castro-Raucci LMS, Gordon JAR, Tye CE, Stein GS, Lian JB, Stein JL, Rosa AL, Beloti MM. Titanium with nanotopography attenuates the osteoclast-induced disruption of osteoblast differentiation by regulating histone methylation. Materials Science & Engineering. C, Materials For Biological Applications. 112548. PMID 35012895 DOI: 10.1016/j.msec.2021.112548  0.327
2020 Rose JT, Moskovitz E, Boyd JR, Gordon JA, Bouffard NA, Fritz AJ, Illendula A, Bushweller JH, Lian JB, Stein JL, Zaidi SK, Stein GS. Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking. Oncotarget. 11: 2512-2530. PMID 32655837 DOI: 10.18632/Oncotarget.27637  0.47
2020 Galea GL, Paradise CR, Meakin LB, Camilleri ET, Taipaleenmaki H, Stein GS, Lanyon LE, Price JS, van Wijnen AJ, Dudakovic A. Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2. Gene: X. 5: 100027. PMID 32550554 DOI: 10.1016/J.Gene.2020.100027  0.391
2020 Fritz AJ, Hong D, Boyd J, Kost J, Finstaad KH, Fitzgerald MP, Hanna S, Abuarqoub AH, Malik M, Bushweller J, Tye C, Ghule P, Gordon J, Frietze S, Zaidi SK, ... ... Stein GS, et al. RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells. Journal of Cellular Physiology. PMID 32180230 DOI: 10.1002/Jcp.29625  0.36
2020 Farina NH, Scalia S, Adams CE, Hong D, Fritz AJ, Messier TL, Balatti V, Veneziano D, Lian JB, Croce CM, Stein GS, Stein JL. Identification of tRNA-derived small RNA (tsRNA) responsive to the tumor suppressor, RUNX1, in breast cancer. Journal of Cellular Physiology. PMID 31919859 DOI: 10.1002/Jcp.29419  0.338
2020 Moena D, Nardocci G, Acevedo E, Lian J, Stein G, Stein J, Montecino M. Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells. Journal of Cellular Physiology. PMID 31907922 DOI: 10.1002/Jcp.29428  0.466
2019 Paradise CR, Galvan ML, Kubrova E, Bowden S, Liu E, Carstens MF, Thaler R, Stein GS, van Wijnen AJ, Dudakovic A. The epigenetic reader Brd4 is required for osteoblast differentiation. Journal of Cellular Physiology. PMID 31868237 DOI: 10.1002/Jcp.29415  0.479
2019 Moena D, Merino P, Lian JB, Stein GS, Stein JL, Montecino M. Switches in histone modifications epigenetically control vitamin D3-dependent transcriptional upregulation of the CYP24A1 gene in osteoblastic cells. Journal of Cellular Physiology. PMID 31868234 DOI: 10.1002/Jcp.29420  0.436
2019 Bolf EL, Gillis NE, Barnum MS, Beaudet CM, Yu GY, Tomczak JA, Stein JL, Lian JB, Stein GS, Carr FE. The Thyroid Hormone Receptor-RUNX2 Axis: A Novel Tumor Suppressive Pathway in Breast Cancer. Hormones & Cancer. PMID 31865591 DOI: 10.1007/S12672-019-00373-2  0.322
2019 Toor RH, Malik S, Qamar H, Batool F, Tariq M, Nasir Z, Tassaduq R, Lian JB, Stein JL, Stein GS, Shakoori AR. Osteogenic potential of hexane and dichloromethane fraction of Cissus quadrangularis on murine preosteoblast cell line MC3T3-E1 (subclone 4). Journal of Cellular Physiology. PMID 31131449 DOI: 10.1002/Jcp.28869  0.355
2019 Heath JL, Cohn GM, Zaidi SK, Stein GS. The role of cell adhesion in hematopoiesis and leukemogenesis. Journal of Cellular Physiology. PMID 30980400 DOI: 10.1002/Jcp.28636  0.376
2019 Averill AM, Rehman HT, Charles JW, Dinh TA, Danyal K, Verschraegen CF, Stein GS, Dostmann WR, Ramsey JE. Inhibition of the chimeric DnaJ-PKAc enzyme by endogenous inhibitor proteins. Journal of Cellular Biochemistry. PMID 30938854 DOI: 10.1002/Jcb.28651  0.37
2019 Fritz AJ, Gillis NE, Gerrard DL, Rodriguez PD, Hong D, Rose JT, Ghule PN, Bolf EL, Gordon JA, Tye CE, Boyd JR, Tracy KM, Nickerson JA, van Wijnen AJ, Imbalzano AN, ... ... Stein GS, et al. Higher order genomic organization and epigenetic control maintain cellular identity and prevent breast cancer. Genes, Chromosomes & Cancer. PMID 30873710 DOI: 10.1002/Gcc.22731  0.336
2019 Lopes HB, Freitas GP, Elias CN, Tye C, Stein JL, Stein GS, Lian JB, Rosa AL, Beloti MM. Participation of Integrin β3 in Osteoblast Differentiation Induced by Titanium with Nano or Microtopography. Journal of Biomedical Materials Research. Part A. PMID 30707485 DOI: 10.1002/Jbm.A.36643  0.318
2019 Villanueva F, Araya H, Briceño P, Varela N, Stevenson A, Jerez S, Tempio F, Chnaiderman J, Perez C, Villarroel M, Concha E, Khani F, Thaler R, Salazar-Onfray F, Stein GS, et al. The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis. Journal of Cellular Physiology. PMID 30637720 DOI: 10.1002/Jcp.28046  0.442
2018 Hong D, Fritz AJ, Gordon JA, Tye CE, Boyd JR, Tracy KM, Frietze SE, Carr FE, Nickerson JA, Van Wijnen AJ, Imbalzano AN, Zaidi SK, Lian JB, Stein JL, Stein GS. RUNX1-dependent mechanisms in biological control and dysregulation in cancer. Journal of Cellular Physiology. PMID 30515788 DOI: 10.1002/Jcp.27841  0.337
2018 Toor RH, Tasadduq R, Adhikari A, Chaudhary MI, Lian JB, Stein JL, Stein GS, Shakoori AR. Ethyl acetate and n-butanol fraction of Cissus quadrangularis promotes the mineralization potential of murine pre-osteoblast cell line MC3T3-E1 (sub-clone 4). Journal of Cellular Physiology. PMID 30443977 DOI: 10.1002/Jcp.27707  0.35
2018 Rojas A, Sepulveda H, Henriquez B, Aguilar R, Opazo T, Nardocci G, Bustos F, Lian JB, Stein JL, Stein GS, van Zundert B, van Wijnen AJ, Allende ML, Montecino M. Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts. Journal of Cellular Physiology. PMID 30256410 DOI: 10.1002/Jcp.27355  0.425
2018 Hong D, Fritz AJ, Finstad KH, Fitzgerald MP, Weinheimer A, Viens AL, Ramsey J, Stein JL, Lian JB, Stein GS. Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor. Molecular Cancer Research : McR. PMID 30082484 DOI: 10.1158/1541-7786.Mcr-18-0135  0.34
2018 Zaidi SK, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS. Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Phenotypes. Molecular Cancer Research : McR. PMID 30002192 DOI: 10.1158/1541-7786.Mcr-18-0415  0.493
2018 Araya HF, Sepulveda H, Lizama CO, Vega OA, Jerez S, Briceño PF, Thaler R, Riester SM, Antonelli M, Salazar-Onfray F, Rodríguez JP, Moreno RD, Montecino M, Charbonneau M, Dubois CM, ... Stein GS, et al. Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2. Journal of Cellular Biochemistry. PMID 29923217 DOI: 10.1002/Jcb.26832  0.495
2018 Zaidi SK, Fritz A, Tracy K, Gordon J, Tye C, Boyd J, Van Wijnen A, Nickerson J, Imbalzano A, Lian J, Stein J, Stein G. Nuclear organization mediates cancer-compromised genetic and epigenetic control. Advances in Biological Regulation. PMID 29759441 DOI: 10.1016/J.Jbior.2018.05.001  0.439
2018 Gillis NE, Taber TH, Bolf EL, Beaudet CM, Tomczak JA, White JH, Stein JL, Stein GS, Lian JB, Frietze S, Carr FE. Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling. Endocrinology. PMID 29750276 DOI: 10.1210/En.2018-00128  0.458
2018 Tye CE, Boyd JR, Page NA, Falcone MM, Stein JL, Stein GS, Lian JB. Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation. Connective Tissue Research. 59: 35-41. PMID 29745821 DOI: 10.1080/03008207.2017.1412432  0.4
2018 Ghule PN, Seward DJ, Fritz AJ, Boyd JR, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition. Journal of Cellular Physiology. PMID 29744889 DOI: 10.1002/Jcp.26741  0.461
2018 Tracy KM, Tye CE, Ghule PN, Malaby HLH, Stumpff J, Stein JL, Stein GS, Lian JB. Mitotically-associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer. Molecular Cancer Research : McR. PMID 29378907 DOI: 10.1158/1541-7786.Mcr-17-0548  0.358
2018 Hong D, Fritz AJ, Tye CE, Page NA, Boyd JR, Lian JB, Stein JL, Stein GS. Abstract 4462: RUNX1 global binding and gene regulation in mammary epithelial cells revealed novel Runx1 mediated cellular activities Cancer Research. 78: 4462-4462. DOI: 10.1158/1538-7445.Am2018-4462  0.468
2018 Othman AH, Tandon M, Ashok V, Winogradzki M, Stein G, Pratap J. Abstract 43: Regulation of autophagy in bone metastatic breast cancer cells Cancer Research. 78: 43-43. DOI: 10.1158/1538-7445.Am2018-43  0.379
2017 Tai PWL, Wu H, van Wijnen AJ, Stein GS, Stein JL, Lian JB. Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation. Plos One. 12: e0188056. PMID 29176792 DOI: 10.1371/Journal.Pone.0188056  0.458
2017 Ramsey J, Butnor K, Peng Z, Leclair T, van der Velden J, Stein G, Lian J, Kinsey CM. LOSS OF RUNX1 IS ASSOCIATED WITH AGGRESSIVE LUNG ADENOCARCINOMAS. Journal of Cellular Physiology. PMID 28926105 DOI: 10.1002/Jcp.26201  0.38
2017 Zaidi SK, Frietze SE, Gordon JA, Heath JL, Messier T, Hong D, Boyd JR, Kang M, Imbalzano AN, Lian JB, Stein JL, Stein GS. Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer. Molecular and Cellular Biology. PMID 28923849 DOI: 10.1128/Mcb.00352-17  0.456
2017 Balatti V, Nigita G, Veneziano D, Drusco A, Stein GS, Messier TL, Farina NH, Lian JB, Tomasello L, Liu CG, Palamarchuk A, Hart JR, Bell C, Carosi M, Pescarmona E, et al. tsRNA signatures in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28696308 DOI: 10.1073/Pnas.1706908114  0.384
2017 Zaidi SK, Perez AW, White ES, Lian JB, Stein JL, Stein GS. An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells. Oncotarget. PMID 28611288 DOI: 10.18632/Oncotarget.18127  0.316
2017 Fritz AJ, Ghule PN, Boyd JR, Tye CE, Page NA, Hong D, Weinheimer AS, Barutcu AR, Gerrard DL, Frietze S, Zaidi SK, Imbalzano A, Lian JB, Stein JL, Stein GS. Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer. Journal of Cellular Physiology. PMID 28504305 DOI: 10.1002/Jcp.25996  0.395
2017 Tracy KM, Tye CE, Page NA, Fritz AJ, Stein JL, Lian JB, Stein GS. Selective expression of long non-coding RNAs in a breast cancer cell progression model. Journal of Cellular Physiology. PMID 28488769 DOI: 10.1002/Jcp.25997  0.303
2017 Hong D, Messier TL, Tye CE, Dobson JR, Fritz AJ, Sikora KR, Browne G, Stein JL, Lian JB, Stein GS. Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition. Oncotarget. 8: 17610-17627. PMID 28407681 DOI: 10.18632/Oncotarget.15381  0.395
2017 Vega OA, Lucero CM, Araya HF, Jerez S, Tapia JC, Antonelli M, Salazar-Onfray F, Las Heras F, Thaler R, Riester SM, Stein GS, van Wijnen AJ, Galindo MA. Wnt/β-catenin Signaling Activates Expression of the Bone-related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types. Journal of Cellular Biochemistry. PMID 28370561 DOI: 10.1002/Jcb.26011  0.388
2017 Tandon M, Othman AH, Ashok V, Stein GS, Pratap J. The Role of Runx2 in Facilitating Autophagy in Metastatic Breast Cancer Cells. Journal of Cellular Physiology. PMID 28345763 DOI: 10.1002/Jcp.25916  0.352
2017 Zaidi SK, Lian JB, van Wijnen A, Stein JL, Stein GS. Mitotic Gene Bookmarking: An Epigenetic Mechanism for Coordination of Lineage Commitment, Cell Identity and Cell Growth. Advances in Experimental Medicine and Biology. 962: 95-102. PMID 28299653 DOI: 10.1007/978-981-10-3233-2_7  0.491
2017 Reagan MR, Lian J, Rosen CJ, Stein G. A Perspective on Malignancy in the Marrow. Journal of Cellular Physiology. PMID 28206683 DOI: 10.1002/Jcp.25860  0.305
2017 Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ. Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing. Gene. PMID 28132772 DOI: 10.1016/J.Gene.2017.01.019  0.417
2017 Colden M, Dar AA, Saini S, Dahiya PV, Shahryari V, Yamamura S, Tanaka Y, Stein G, Dahiya R, Majid S. MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2. Cell Death & Disease. 8: e2572. PMID 28125091 DOI: 10.1038/Cddis.2017.15  0.319
2017 Wu H, Gordon JA, Whitfield TW, Tai PW, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Chromatin Dynamics Regulate Mesenchymal Stem Cell Lineage Specification and Differentiation to Osteogenesis. Biochimica Et Biophysica Acta. PMID 28077316 DOI: 10.1016/J.Bbagrm.2017.01.003  0.473
2017 Hong D, J A, Fritz KF, Fitzgerald MP, Stein JL, Lian J, Stein GS. Abstract 5534: Runx1 possesses anti-tumor activity and inhibits stemness in breast cancer cells Cancer Research. 77: 5534-5534. DOI: 10.1158/1538-7445.Am2017-5534  0.33
2016 Farzaneh K, Thaler R, Paradise CR, Deyle DR, Kruijthof-de Julio M, Galindo M, Gordon JA, Stein GS, Dudakovic A, van Wijnen AJ. Histone H4 Methyltransferase Suv420h2 Maintains Fidelity of Osteoblast Differentiation. Journal of Cellular Biochemistry. PMID 27862226 DOI: 10.1002/Jcb.25787  0.448
2016 Dudakovic A, Camilleri ET, Riester SM, Paradise CR, Gluscevic M, O'Toole TM, Thaler R, Evans JM, Yan H, Subramaniam M, Hawse JR, Stein GS, Montecino MA, McGee-Lawrence ME, Westendorf JJ, et al. Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Due to Ovariectomy in Skeletally Mature Mice. The Journal of Biological Chemistry. PMID 27758858 DOI: 10.1074/Jbc.M116.740571  0.384
2016 Taipaleenmäki H, Farina NH, van Wijnen AJ, Stein JL, Hesse E, Stein GS, Lian JB. Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells. Oncotarget. PMID 27738322 DOI: 10.18632/Oncotarget.12593  0.33
2016 VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS. Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling. Stem Cell Reports. PMID 27720906 DOI: 10.1016/J.Stemcr.2016.09.006  0.394
2016 Underwood JM, Becker K, Stein GS, Nickerson JA. The Ultrastructural Signature of Human Embryonic Stem Cells. Journal of Cellular Biochemistry. PMID 27632380 DOI: 10.1002/Jcb.25736  0.395
2016 Dobson JR, Hong D, Barutcu AR, Wu H, Imbalzano AN, Lian JB, Stein JL, van Wijnen AJ, Nickerson JA, Stein GS. Identifying Nuclear Matrix-Attached DNA Across the Genome. Journal of Cellular Physiology. PMID 27627025 DOI: 10.1002/Jcp.25596  0.446
2016 Ghule PN, Xie RL, Colby JL, Rivera-Pérez JA, Jones SN, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos. Developmental Biology. PMID 27609454 DOI: 10.1016/J.Ydbio.2016.09.003  0.478
2016 VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein G. Precocious Phenotypic Transcription-Factor Expression during Early Development. Journal of Cellular Biochemistry. PMID 27591551 DOI: 10.1002/Jcb.25723  0.413
2016 VanOudenhove JJ, Grandy RA, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS. Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle. Journal of Cellular Physiology. PMID 27532275 DOI: 10.1002/Jcp.25567  0.345
2016 Barutcu AR, Hong D, Lajoie BR, McCord RP, van Wijnen AJ, Lian JB, Stein JL, Dekker J, Imbalzano AN, Stein GS. RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. Biochimica Et Biophysica Acta. PMID 27514584 DOI: 10.1016/J.Bbagrm.2016.08.003  0.439
2016 Barutcu AR, Lajoie BR, Fritz AJ, McCord RP, Nickerson JA, van Wijnen AJ, Lian JB, Stein JL, Dekker J, Stein GS, Imbalzano AN. SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells. Genome Research. PMID 27435934 DOI: 10.1101/Gr.201624.115  0.461
2016 Jerez S, Araya H, Thaler R, Charlesworth MC, López-Solís R, Kalergis AM, Céspedes PF, Dudakovic A, Stein GS, van Wijnen AJ, Galindo M. Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression. Journal of Cellular Biochemistry. PMID 27356893 DOI: 10.1002/Jcb.25642  0.343
2016 Tasadduq R, Gordon J, Al-Ghanim KA, Lian JB, Van Wijnen AJ, Stein JL, Stein GS, Shakoori AR. Ethanol Extract of Cissus quadrangularis Enhances Osteoblast Differentiation and Mineralization of Murine Pre-Osteoblastic MC3T3-E1 Cells. Journal of Cellular Physiology. PMID 27264191 DOI: 10.1002/Jcp.25449  0.314
2016 Carr FE, Tai PW, Barnum MS, Gillis NE, Evans KG, Taber TH, White JH, Tomczak JA, Jaworski DM, Zaidi SK, Lian JB, Stein JL, Stein GS. Thyroid Hormone Receptor β (TRβ) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A novel signaling pathway in thyroid cancer. Endocrinology. en20152046. PMID 27253998 DOI: 10.1210/En.2015-2046  0.366
2016 Wu Q, Madany P, Dobson JR, Schnabl JM, Sharma S, Smith TC, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Muthuswami R, Imbalzano AN, Nickerson JA. The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation. Oncotarget. PMID 27223259 DOI: 10.18632/Oncotarget.9505  0.323
2016 Zheng L, Tu Q, Meng S, Zhang L, Yu L, Song J, Hu Y, Sui L, Zhang J, Dard M, Cheng J, Murray D, Lian J, Stein G, Chen J. Runx2/DICER/miRNA Pathway in Regulating Osteogenesis. Journal of Cellular Physiology. PMID 27064596 DOI: 10.1002/Jcp.25406  0.38
2016 VanOudenhove JJ, Grandy RA, Ghule PN, Del Rio R, Lian JB, Stein JL, Zaidi SK, Stein GS. Lineage-Specific Early Differentiation of Human Embryonic Stem Cells Requires a G2 Cell Cycle Pause. Stem Cells (Dayton, Ohio). PMID 26946228 DOI: 10.1002/Stem.2352  0.385
2016 Messier TL, Boyd JR, Gordon JA, Stein JL, Lian JB, Stein GS. Oncofetal Epigenetic Bivalency in Breast Cancer Cells: H3K4 and H3K27 Methylation as a Biomarker for Phenotypic Plasticity(†). Journal of Cellular Physiology. PMID 26916849 DOI: 10.1002/Jcp.25359  0.41
2016 Martinez M, Hinojosa M, Trombly D, Morin V, Stein J, Stein G, Javed A, Gutierrez SE. Transcriptional Auto-Regulation of RUNX1 P1 Promoter. Plos One. 11: e0149119. PMID 26901859 DOI: 10.1371/Journal.Pone.0149119  0.462
2016 Lim KE, Park NR, Che X, Han MS, Jeong JH, Kim SY, Park CY, Akiyama H, Kim JE, Ryoo HM, Stein JL, Lian JB, Stein GS, Choi JY. Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass via Stabilization of Runx2 in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 31: 245. PMID 26804813 DOI: 10.1002/Jbmr.2587  0.345
2016 Messier TL, Gordon JA, Boyd JR, Tye CE, Browne G, Stein JL, Lian JB, Stein GS. Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes. Oncotarget. PMID 26783963 DOI: 10.18632/Oncotarget.6922  0.385
2016 Zaidi SK, Boyd JR, Grandy R, Medina R, Lian JB, Stein GS, Stein JL. Expression of Ribosomal RNA and Protein Genes in Human Embryonic Stem Cells Is Associated with the Activating H3K4me3 Histone Mark. Journal of Cellular Physiology. PMID 26755341 DOI: 10.1002/Jcp.25309  0.487
2016 Browne G, Dragon JA, Hong D, Messier TL, Gordon JA, Farina NH, Boyd JR, VanOudenhove JJ, Perez AW, Zaidi SK, Stein JL, Stein GS, Lian JB. MicroRNA-378-mediated suppression of Runx1 alleviates the aggressive phenotype of triple-negative MDA-MB-231 human breast cancer cells. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26749280 DOI: 10.1007/S13277-015-4710-6  0.311
2016 Hong D, Messier T, Fritz A, Browne G, Stein J, Lian J, Stein G. Abstract 1178: Runx1 is obligatory for mammary epithelial cell morphology and phenotype Cancer Research. 76: 1178-1178. DOI: 10.1158/1538-7445.Am2016-1178  0.369
2015 Grandy RA, Whitfield TW, Wu H, Fitzgerald MP, VanOudenhove JJ, Zaidi SK, Montecino MA, Lian JB, vanWijnen AJ, Stein JL, Stein GS. Genome-wide Studies Reveal that H3K4me3 Modification in Bivalent Genes is Dynamically Regulated During the Pluripotent Cell Cycle and Stabilized Upon Differentiation. Molecular and Cellular Biology. PMID 26644406 DOI: 10.1128/Mcb.00877-15  0.451
2015 Rojas A, Aguilar R, Henriquez B, Lian JB, Stein JL, Stein GS, van Wijnen AJ, van Zundert B, Allende ML, Montecino M. Epigenetic Control of the Bone-master Runx2 Gene During Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B. The Journal of Biological Chemistry. PMID 26453309 DOI: 10.1074/Jbc.M115.657825  0.482
2015 Dudakovic A, Camilleri ET, Xu F, Riester SM, McGee-Lawrence ME, Bradley EW, Paradise CR, Lewallen EA, Thaler R, Deyle DR, Larson AN, Lewallen DG, Dietz AB, Stein GS, Montecino MA, et al. Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2. The Journal of Biological Chemistry. PMID 26424790 DOI: 10.1074/Jbc.M115.672345  0.478
2015 Barutcu AR, Lajoie BR, McCord RP, Tye CE, Hong D, Messier TL, Browne G, van Wijnen AJ, Lian JB, Stein JL, Dekker J, Imbalzano AN, Stein GS. Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells. Genome Biology. 16: 214. PMID 26415882 DOI: 10.1186/S13059-015-0768-0  0.355
2015 Varela N, Aranguiz A, Lizama C, Sepulveda H, Antonelli M, Thaler R, Moreno RD, Montecino M, Stein GS, van Wijnen AJ, Galindo M. Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells. Journal of Cellular Physiology. PMID 26381402 DOI: 10.1002/Jcp.25188  0.513
2015 Barutcu AR, Fritz AJ, Zaidi SK, vanWijnen AJ, Lian JB, Stein JL, Nickerson JA, Imbalzano AN, Stein GS. C-ing the Genome: A Compendium of Chromosome Conformation Capture Methods to Study Higher-Order Chromatin Organization. Journal of Cellular Physiology. PMID 26059817 DOI: 10.1002/Jcp.25062  0.31
2015 Hassan MQ, Tye CE, Stein GS, Lian JB. Non-coding RNAs: Epigenetic regulators of bone development and homeostasis. Bone. PMID 26039869 DOI: 10.1016/J.Bone.2015.05.026  0.337
2015 Ghule PN, Xie RL, Colby JL, Jones SN, Lian JB, van Wijnen AJ, Stein JL, Stein GS. p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency. Cell Cycle (Georgetown, Tex.). 1-8. PMID 26030398 DOI: 10.1080/15384101.2015.1049783  0.395
2015 Trombly DJ, Whitfield TW, Padmanabhan S, Gordon JA, Lian JB, van Wijnen AJ, Zaidi SK, Stein JL, Stein GS. Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells. Bmc Genomics. 16: 309. PMID 25928846 DOI: 10.1186/S12864-015-1445-0  0.355
2015 Montecino M, Stein G, Stein J, Zaidi K, Aguilar R. Multiple levels of epigenetic control for bone biology and pathology. Bone. PMID 25865577 DOI: 10.1016/J.Bone.2015.03.013  0.467
2015 Wu Q, Madany P, Akech J, Dobson JR, Douthwright S, Browne G, Colby JL, Winter GE, Bradner JE, Pratap J, Sluder G, Bhargava R, Chiosea S, van Wijnen AJ, Stein JL, ... Stein GS, et al. The SWI/SNF ATPases are Required for Triple Negative Breast Cancer Cell Proliferation. Journal of Cellular Physiology. PMID 25808524 DOI: 10.1002/Jcp.24991  0.359
2015 Scott RE, Ghule PN, Stein JL, Stein GS. Cell cycle gene expression networks discovered using systems biology: Significance in carcinogenesis. Journal of Cellular Physiology. 230: 2533-42. PMID 25808367 DOI: 10.1002/Jcp.24990  0.414
2015 Zhang X, Wu H, Dobson JR, Browne G, Hong D, Akech J, Languino LR, Stein JL, Stein GS, Lian JB. Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1. Journal of Cellular Biochemistry. PMID 25808168 DOI: 10.1002/Jcb.25167  0.345
2015 Browne G, Taipaleenmäki H, Bishop NM, Madasu SC, Shaw LM, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion. Journal of Cellular Physiology. 230: 2522-32. PMID 25802202 DOI: 10.1002/Jcp.24989  0.341
2015 Taipaleenmäki H, Browne G, Akech J, Zustin J, van Wijnen AJ, Stein JL, Hesse E, Stein GS, Lian JB. Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease. Cancer Research. 75: 1433-44. PMID 25634212 DOI: 10.1158/0008-5472.Can-14-1026  0.308
2015 Yang S, Quaresma AJ, Nickerson JA, Green KM, Shaffer SA, Imbalzano AN, Martin-Buley LA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response. Journal of Cell Science. 128: 728-40. PMID 25609707 DOI: 10.1242/Jcs.160051  0.437
2015 Lim KE, Park NR, Che X, Han MS, Jeong JH, Kim SY, Park CY, Akiyama H, Kim JE, Ryoo HM, Stein JL, Lian JB, Stein GS, Choi JY. Core binding factor β of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 715-22. PMID 25358268 DOI: 10.1002/Jbmr.2397  0.345
2015 Galea GL, Meakin LB, Savery D, Taipaleenmaki H, Delisser P, Stein GS, Copp AJ, van Wijnen AJ, Lanyon LE, Price JS. Planar cell polarity aligns osteoblast division in response to substrate strain. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 423-35. PMID 25264362 DOI: 10.1002/Jbmr.2377  0.327
2015 Tye CE, Gordon JA, Martin-Buley LA, Stein JL, Lian JB, Stein GS. Could lncRNAs be the missing links in control of mesenchymal stem cell differentiation? Journal of Cellular Physiology. 230: 526-34. PMID 25258250 DOI: 10.1002/Jcp.24834  0.34
2015 Zhang X, Akech J, Browne G, Russell S, Wixted JJ, Stein JL, Stein GS, Lian JB. Runx2-Smad signaling impacts the progression of tumor-induced bone disease. International Journal of Cancer. Journal International Du Cancer. 136: 1321-32. PMID 25053011 DOI: 10.1002/Ijc.29094  0.364
2015 Dudakovic A, Camilleri ET, Lewallen EA, McGee-Lawrence ME, Riester SM, Kakar S, Montecino M, Stein GS, Ryoo HM, Dietz AB, Westendorf JJ, van Wijnen AJ. Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells. Journal of Cellular Physiology. 230: 52-62. PMID 24912092 DOI: 10.1002/Jcp.24680  0.431
2015 Kapinas K, Kim H, Mandeville M, Martin-Buley LA, Croce CM, Lian JB, van Wijnen AJ, Stein JL, Altieri DC, Stein GS. microRNA-mediated survivin control of pluripotency. Journal of Cellular Physiology. 230: 63-70. PMID 24891298 DOI: 10.1002/Jcp.24681  0.394
2015 Trombly DJ, Whitfield TW, Padmanabhan S, Gordon JA, Lian JB, Wijnen AJv, Zaidi SK, Stein JL, Stein GS. Abstract B28: Co-occupancy of AML1-ETO and N-CoR defines a dominant phenotypic signature in leukemic cells. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-B28  0.443
2014 Gordon JA, Montecino MA, Aqeilan RI, Stein JL, Stein GS, Lian JB. Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders. Current Osteoporosis Reports. 12: 496-506. PMID 25260661 DOI: 10.1007/S11914-014-0240-1  0.425
2014 Barutcu AR, Tai PW, Wu H, Gordon JA, Whitfield TW, Dobson JR, Imbalzano AN, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter. Nucleic Acids Research. 42: 10360-72. PMID 25120271 DOI: 10.1093/Nar/Gku712  0.464
2014 Lopez-Camacho C, van Wijnen AJ, Lian JB, Stein JL, Stein GS. CBFβ and the leukemogenic fusion protein CBFβ-SMMHC associate with mitotic chromosomes to epigenetically regulate ribosomal genes. Journal of Cellular Biochemistry. 115: 2155-64. PMID 25079347 DOI: 10.1002/Jcb.24892  0.482
2014 LeBlanc KT, Walcott ME, Gaur T, O'Connell SL, Basil K, Tadiri CP, Mason-Savas A, Silva JA, van Wijnen AJ, Stein JL, Stein GS, Ayers DC, Lian JB, Fanning PJ. Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading. Journal of Cellular Physiology. PMID 25078095 DOI: 10.1002/Jcp.24727  0.386
2014 Lamba G, Zaidi SK, Luebbers K, Verschraegen C, Stein GS, Rosmarin A. Epigenetic landscape of acute myelogenous leukemia--moving toward personalized medicine. Journal of Cellular Biochemistry. 115: 1669-72. PMID 24905899 DOI: 10.1002/Jcb.24853  0.334
2014 Dudakovic A, Camilleri E, Riester SM, Lewallen EA, Kvasha S, Chen X, Radel DJ, Anderson JM, Nair AA, Evans JM, Krych AJ, Smith J, Deyle DR, Stein JL, Stein GS, et al. High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells. Journal of Cellular Biochemistry. 115: 1816-28. PMID 24905804 DOI: 10.1002/Jcb.24852  0.402
2014 Tai PW, Wu H, Gordon JA, Whitfield TW, Barutcu AR, van Wijnen AJ, Lian JB, Stein GS, Stein JL. Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region. Gene. 550: 1-9. PMID 24881813 DOI: 10.1016/J.Gene.2014.05.044  0.412
2014 Browne G, Taipaleenmäki H, Stein GS, Stein JL, Lian JB. MicroRNAs in the control of metastatic bone disease. Trends in Endocrinology and Metabolism: Tem. 25: 320-7. PMID 24811921 DOI: 10.1016/J.Tem.2014.03.014  0.311
2014 Ghule PN, Xie RL, Medina R, Colby JL, Jones SN, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Fidelity of histone gene regulation is obligatory for genome replication and stability. Molecular and Cellular Biology. 34: 2650-9. PMID 24797072 DOI: 10.1128/Mcb.01567-13  0.416
2014 Wu H, Whitfield TW, Gordon JA, Dobson JR, Tai PW, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis. Genome Biology. 15: R52. PMID 24655370 DOI: 10.1186/Gb-2014-15-3-R52  0.417
2014 Lopez-Camacho C, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Core binding factor β (CBFβ) is retained in the midbody during cytokinesis. Journal of Cellular Physiology. 229: 1466-74. PMID 24648201 DOI: 10.1002/Jcp.24588  0.415
2014 Aguilar R, Grandy R, Meza D, Sepulveda H, Pihan P, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. A functional N-terminal domain in C/EBPβ-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts. Journal of Cellular Physiology. 229: 1521-8. PMID 24585571 DOI: 10.1002/Jcp.24595  0.401
2014 Zaidi SK, Grandy RA, Lopez-Camacho C, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes? Cancer Research. 74: 420-5. PMID 24408924 DOI: 10.1158/0008-5472.Can-13-2837  0.487
2014 Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, et al. Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2. Cancer Research. 74: 1598-608. PMID 24385215 DOI: 10.1158/0008-5472.Can-13-1796  0.342
2014 Okolicsanyi RK, van Wijnen AJ, Cool SM, Stein GS, Griffiths LR, Haupt LM. Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity. Journal of Cellular Biochemistry. 115: 967-76. PMID 24357546 DOI: 10.1002/Jcb.24746  0.414
2014 Tai PW, Zaidi SK, Wu H, Grandy RA, Montecino M, van Wijnen AJ, Lian JB, Stein GS, Stein JL. The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease. Journal of Cellular Physiology. 229: 711-27. PMID 24242872 DOI: 10.1002/Jcp.24508  0.372
2014 Browne G, Bishop NM, Dobson JR, Madasu SC, Nicholas FH, Porta MLL, Frederick D, Colby JL, Shaw LM, Landis J, Stein JL, Lian JB, Stein GS. Abstract 3524: Unraveling the dichotomy of Runx1 in breast cancer Cancer Research. 74: 3524-3524. DOI: 10.1158/1538-7445.Am2014-3524  0.346
2013 Lian JB, Gordon JA, Stein GS. Redefining the activity of a bone-specific transcription factor: novel insights for understanding bone formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2060-3. PMID 23966343 DOI: 10.1002/Jbmr.2076  0.352
2013 Dowdy CR, Frederick D, Zaidi SK, Colby JL, Lian JB, van Wijnen AJ, Gerstein RM, Stein JL, Stein GS. A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation. Experimental Hematology. 41: 980-991.e1. PMID 23823022 DOI: 10.1016/J.Exphem.2013.06.006  0.362
2013 van der Deen M, Taipaleenmäki H, Zhang Y, Teplyuk NM, Gupta A, Cinghu S, Shogren K, Maran A, Yaszemski MJ, Ling L, Cool SM, Leong DT, Dierkes C, Zustin J, Salto-Tellez M, ... ... Stein GS, et al. MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma. The Journal of Biological Chemistry. 288: 21307-19. PMID 23720736 DOI: 10.1074/Jbc.M112.445890  0.365
2013 Yoon WJ, Islam R, Cho YD, Woo KM, Baek JH, Uchida T, Komori T, van Wijnen A, Stein JL, Lian JB, Stein GS, Choi JY, Bae SC, Ryoo HM. Pin1-mediated Runx2 modification is critical for skeletal development. Journal of Cellular Physiology. 228: 2377-85. PMID 23702614 DOI: 10.1002/Jcp.24403  0.355
2013 van Wijnen AJ, van de Peppel J, van Leeuwen JP, Lian JB, Stein GS, Westendorf JJ, Oursler MJ, Im HJ, Taipaleenmäki H, Hesse E, Riester S, Kakar S. MicroRNA functions in osteogenesis and dysfunctions in osteoporosis. Current Osteoporosis Reports. 11: 72-82. PMID 23605904 DOI: 10.1007/S11914-013-0143-6  0.306
2013 Zaidi SK, Van Wijnen AJ, Lian JB, Stein JL, Stein GS. Targeting deregulated epigenetic control in cancer. Journal of Cellular Physiology. 228: 2103-8. PMID 23589100 DOI: 10.1002/Jcp.24387  0.381
2013 Pande S, Browne G, Padmanabhan S, Zaidi SK, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells. Journal of Cellular Physiology. 228: 1784-92. PMID 23389849 DOI: 10.1002/Jcp.24339  0.404
2013 Galea GL, Meakin LB, Sugiyama T, Zebda N, Sunters A, Taipaleenmaki H, Stein GS, van Wijnen AJ, Lanyon LE, Price JS. Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β. The Journal of Biological Chemistry. 288: 9035-48. PMID 23362266 DOI: 10.1074/Jbc.M112.405456  0.337
2013 McGee-Lawrence ME, Li X, Bledsoe KL, Wu H, Hawse JR, Subramaniam M, Razidlo DF, Stensgard BA, Stein GS, van Wijnen AJ, Lian JB, Hsu W, Westendorf JJ. Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice. The Journal of Biological Chemistry. 288: 5291-302. PMID 23300083 DOI: 10.1074/Jbc.M112.414995  0.376
2013 Abdeen SK, Del Mare S, Hussain S, Abu-Remaileh M, Salah Z, Hagan J, Rawahneh M, Pu XA, Russell S, Stein JL, Stein GS, Lian JB, Aqeilan RI. Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype. Journal of Cellular Physiology. 228: 1377-82. PMID 23254685 DOI: 10.1002/Jcp.24308  0.346
2013 Hovhannisyan H, Zhang Y, Hassan MQ, Wu H, Glackin C, Lian JB, Stein JL, Montecino M, Stein GS, van Wijnen AJ. Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene. Journal of Cellular Physiology. 228: 313-21. PMID 22886425 DOI: 10.1002/Jcp.22109  0.309
2013 Kapinas K, Grandy R, Ghule P, Medina R, Becker K, Pardee A, Zaidi SK, Lian J, Stein J, van Wijnen A, Stein G. The abbreviated pluripotent cell cycle. Journal of Cellular Physiology. 228: 9-20. PMID 22552993 DOI: 10.1002/Jcp.24104  0.379
2013 Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, FitzGerald TJ, Jiang Z, Violette SM, Stein GS, Lian JB, Languino LR. Abstract C40: αvβ6 integrin promotes a TGFβ1-mediated cancer cell autonomous osteolytic program through upregulation of matrix metalloproteinase 2 (MMP2) Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C40  0.327
2012 Hassan MQ, Maeda Y, Taipaleenmaki H, Zhang W, Jafferji M, Gordon JA, Li Z, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JB. miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells. The Journal of Biological Chemistry. 287: 42084-92. PMID 23060446 DOI: 10.1074/Jbc.M112.377515  0.353
2012 Zaidi SK, Trombly DJ, Dowdy CR, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Epigenetic mechanisms in leukemia. Advances in Biological Regulation. 52: 369-76. PMID 22884030 DOI: 10.1016/J.Jbior.2012.05.001  0.486
2012 Medina R, Ghule PN, Cruzat F, Barutcu AR, Montecino M, Stein JL, van Wijnen AJ, Stein GS. Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle. Molecular and Cellular Biology. 32: 3860-71. PMID 22826438 DOI: 10.1128/Mcb.00736-12  0.486
2012 Bhakta G, Rai B, Lim ZX, Hui JH, Stein GS, van Wijnen AJ, Nurcombe V, Prestwich GD, Cool SM. Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2. Biomaterials. 33: 6113-22. PMID 22687758 DOI: 10.1016/J.Biomaterials.2012.05.030  0.316
2012 Tandon M, Gokul K, Ali SA, Chen Z, Lian J, Stein GS, Pratap J. Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells. Molecular Cancer. 11: 27. PMID 22537242 DOI: 10.1186/1476-4598-11-27  0.417
2012 Li X, Ellman MB, Kroin JS, Chen D, Yan D, Mikecz K, Ranjan KC, Xiao G, Stein GS, Kim SG, Cole B, van Wijnen AJ, Im HJ. Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family. Journal of Cellular Biochemistry. 113: 2532-42. PMID 22415882 DOI: 10.1002/Jcb.24129  0.315
2012 Stein GS, Stein JL, van J Wijnen A, Lian JB, Montecino M, Medina R, Kapinas K, Ghule P, Grandy R, Zaidi SK, Becker KA. The architectural organization of human stem cell cycle regulatory machinery. Current Pharmaceutical Design. 18: 1679-85. PMID 22394165 DOI: 10.2174/138161212799859639  0.401
2012 Ali SA, Dobson JR, Lian JB, Stein JL, van Wijnen AJ, Zaidi SK, Stein GS. A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation. Journal of Cell Science. 125: 2732-9. PMID 22393235 DOI: 10.1242/Jcs.100909  0.494
2012 Lian JB, Stein GS, van Wijnen AJ, Stein JL, Hassan MQ, Gaur T, Zhang Y. MicroRNA control of bone formation and homeostasis. Nature Reviews. Endocrinology. 8: 212-27. PMID 22290358 DOI: 10.1038/Nrendo.2011.234  0.339
2012 Im HJ, Li X, Chen D, Yan D, Kim J, Ellman MB, Stein GS, Cole B, Kc R, Cs-Szabo G, van Wijnen AJ. Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells. Journal of Cellular Physiology. 227: 3488-97. PMID 22252971 DOI: 10.1002/Jcp.24049  0.347
2012 Bramono DS, Murali S, Rai B, Ling L, Poh WT, Lim ZX, Stein GS, Nurcombe V, van Wijnen AJ, Cool SM. Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2) Bone. 50: 954-964. PMID 22227436 DOI: 10.1016/J.Bone.2011.12.013  0.338
2012 van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ. Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility. The Journal of Biological Chemistry. 287: 4503-17. PMID 22158627 DOI: 10.1074/Jbc.M111.287771  0.478
2012 Helledie T, Dombrowski C, Rai B, Lim ZX, Hin IL, Rider DA, Stein GS, Hong W, van Wijnen AJ, Hui JH, Nurcombe V, Cool SM. Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrow. Stem Cells and Development. 21: 1897-910. PMID 22066689 DOI: 10.1089/Scd.2011.0367  0.374
2012 Min B, Kim MK, Zhang JW, Kim J, Chung KC, Oh BC, Stein GS, Lee YH, van Wijnen AJ, Bae SC. Identification of RUNX3 as a component of the MST/Hpo signaling pathway. Journal of Cellular Physiology. 227: 839-49. PMID 21678419 DOI: 10.1002/Jcp.22887  0.313
2012 Browne G, McCook H, Ming L, Stein JL, Stein GS, Lian JB, McKeown SR, Worthington J. Abstract 4009: Hypoxia potentiates Runx2-mediated increased Bcl-2 expression in prostate cancer resulting in apoptosis resistance Cancer Research. 72: 4009-4009. DOI: 10.1158/1538-7445.Am2012-4009  0.367
2012 Hassan⁎ M, Maeda Y, Jafferji M, Taipaleenmak H, Zhang W, Gordon J, Li Z, Croce C, van Wijnen A, Stein J, Stein G, Lian J. MicroRNA-218 and Wnt signaling regulatory loop promote osteoblast differentiation Bone. 50: S80-S81. DOI: 10.1016/J.Bone.2012.02.234  0.329
2012 Taipaleenmaki H, Deen MVd, Zhang Y, Lian JB, Stein JL, Stein G, Wijnen AJv. Inverse biological coupling between the bone-specific transcription factor Runx2 and the tumor suppressor P53 levels in osteosarcoma Bone. 50. DOI: 10.1016/J.Bone.2012.02.168  0.349
2011 Liu JC, Lengner CJ, Gaur T, Lou Y, Hussain S, Jones MD, Borodic B, Colby JL, Steinman HA, van Wijnen AJ, Stein JL, Jones SN, Stein GS, Lian JB. Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation. The Journal of Biological Chemistry. 286: 30057-70. PMID 21676869 DOI: 10.1074/Jbc.M111.241505  0.381
2011 Liu LJ, Xie R, Hussain S, Lian JB, Rivera-Perez J, Jones SN, Stein JL, Stein GS, van Wijnen AJ. Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. Gene. 483: 1-10. PMID 21605641 DOI: 10.1016/J.Gene.2011.05.002  0.454
2011 Gordon JA, Hassan MQ, Koss M, Montecino M, Selleri L, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex. Cells, Tissues, Organs. 194: 146-50. PMID 21597276 DOI: 10.1159/000324790  0.504
2011 Hawse JR, Cicek M, Grygo SB, Bruinsma ES, Rajamannan NM, van Wijnen AJ, Lian JB, Stein GS, Oursler MJ, Subramaniam M, Spelsberg TC. TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts. Plos One. 6: e19429. PMID 21559363 DOI: 10.1371/Journal.Pone.0019429  0.435
2011 Zaidi SK, Young DW, Montecino M, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Bookmarking the genome: maintenance of epigenetic information. The Journal of Biological Chemistry. 286: 18355-61. PMID 21454629 DOI: 10.1074/Jbc.R110.197061  0.446
2011 Zhang J, Tu Q, Bonewald LF, He X, Stein G, Lian J, Chen J. Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1953-63. PMID 21351149 DOI: 10.1002/Jbmr.377  0.314
2011 Emons J, Dutilh BE, Decker E, Pirzer H, Sticht C, Gretz N, Rappold G, Cameron ER, Neil JC, Stein GS, van Wijnen AJ, Wit JM, Post JN, Karperien M. Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation. The Journal of Endocrinology. 209: 245-54. PMID 21307122 DOI: 10.1530/Joe-10-0219  0.408
2011 Henriquez B, Hepp M, Merino P, Sepulveda H, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells Journal of Cellular Physiology. 226: 3043-3052. PMID 21302301 DOI: 10.1002/Jcp.22652  0.443
2011 McGee-Lawrence ME, McCleary-Wheeler AL, Secreto FJ, Razidlo DF, Zhang M, Stensgard BA, Li X, Stein GS, Lian JB, Westendorf JJ. Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts. Bone. 48: 1117-26. PMID 21255693 DOI: 10.1016/J.Bone.2011.01.007  0.372
2011 Martin JW, Zielenska M, Stein GS, van Wijnen AJ, Squire JA. The Role of RUNX2 in Osteosarcoma Oncogenesis. Sarcoma. 2011: 282745. PMID 21197465 DOI: 10.1155/2011/282745  0.428
2011 Stein GS, Stein JL, van Wijnen AJ, Lian JB, Zaidi SK, Nickerson JA, Montecino MA, Young DW. An architectural genetic and epigenetic perspective. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 297-303. PMID 21184003 DOI: 10.1039/C0Ib00103A  0.379
2011 Ghule PN, Medina R, Lengner CJ, Mandeville M, Qiao M, Dominski Z, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells. Journal of Cellular Physiology. 226: 1149-56. PMID 20945438 DOI: 10.1002/Jcp.22440  0.384
2011 Pockwinse SM, Kota KP, Quaresma AJ, Imbalzano AN, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Nickerson JA. Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression. Journal of Cellular Physiology. 226: 1383-9. PMID 20945391 DOI: 10.1002/Jcp.22465  0.431
2011 Pratap J, Lian JB, Stein GS. Metastatic bone disease: Role of transcription factors and future targets Bone. 48: 30-36. PMID 20561908 DOI: 10.1016/J.Bone.2010.05.035  0.44
2011 Dowdy CR, Frederick D, Zaidi SK, Lian JB, Wijnen Jv, Stein JL, Stein GS. A Subnuclear Targeting Defective Mutant of Runx1 Uncouples the Roles of Runx1 In Embryonic Development and Adult Definitive Hematopoiesis Blood. 118: 1387-1387. DOI: 10.1182/Blood.V118.21.1387.1387  0.424
2011 Tandon M, Gokul K, Ali AS, Lian JB, Stein GS, Pratap J. Abstract 4989: The role of Runx2 in epigenetic silencing of a tumor suppressor BMP-3B/GDF10 in lung cancer cells Cancer Research. 71: 4989-4989. DOI: 10.1158/1538-7445.Am2011-4989  0.41
2011 Zhang Y, Xie R, Stein JL, Lian JB, Wijnen AJv, Stein GS. A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2 Bone. 48. DOI: 10.1016/J.Bone.2011.03.232  0.322
2010 Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss. Molecular Cancer Therapeutics. 9: 3210-20. PMID 21159607 DOI: 10.1158/1535-7163.Mct-10-0572  0.32
2010 Stein GS, van Wijnen AJ, Imbalzano AN, Montecino M, Zaidi SK, Lian JB, Nickerson JA, Stein JL. Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments. Critical Reviews in Eukaryotic Gene Expression. 20: 149-55. PMID 21133844 DOI: 10.1615/Critreveukargeneexpr.V20.I2.50  0.455
2010 Leong DT, Lim J, Goh X, Pratap J, Pereira BP, Kwok HS, Nathan SS, Dobson JR, Lian JB, Ito Y, Voorhoeve PM, Stein GS, Salto-Tellez M, Cool SM, van Wijnen AJ. Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility. Breast Cancer Research : Bcr. 12: R89. PMID 21029421 DOI: 10.1186/Bcr2762  0.448
2010 Jones MD, Liu JC, Barthel TK, Hussain S, Lovria E, Cheng D, Schoonmaker JA, Mulay S, Ayers DC, Bouxsein ML, Stein GS, Mukherjee S, Lian JB. A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4978-89. PMID 20843837 DOI: 10.1158/1078-0432.Ccr-09-3293  0.335
2010 Zaidi SK, Young DW, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information. Molecular and Cellular Biology. 30: 4758-66. PMID 20696837 DOI: 10.1128/Mcb.00646-10  0.477
2010 Zaidi SK, Medina RF, Pockwinse SM, Bakshi R, Kota KP, Ali SA, Young DW, Nickerson JA, Javed A, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Subnuclear localization and intranuclear trafficking of transcription factors. Methods in Molecular Biology (Clifton, N.J.). 647: 77-93. PMID 20694661 DOI: 10.1007/978-1-60761-738-9_4  0.373
2010 Zaidi SK, Young DW, Montecino MA, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Mitotic bookmarking of genes: a novel dimension to epigenetic control. Nature Reviews. Genetics. 11: 583-9. PMID 20628351 DOI: 10.1038/Nrg2827  0.414
2010 Ling L, Dombrowski C, Foong KM, Haupt LM, Stein GS, Nurcombe V, Van Wijnen AJ, Cool SM. Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway Journal of Biological Chemistry. 285: 26233-26244. PMID 20547765 DOI: 10.1074/Jbc.M110.122069  0.35
2010 Kurek KC, Del Mare S, Salah Z, Abdeen S, Sadiq H, Lee SH, Gaudio E, Zanesi N, Jones KB, DeYoung B, Amir G, Gebhardt M, Warman M, Stein GS, Stein JL, et al. Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. Cancer Research. 70: 5577-86. PMID 20530675 DOI: 10.1158/0008-5472.Can-09-4602  0.307
2010 Qiao M, Wang Y, Xu X, Lu J, Dong Y, Tao W, Stein J, Stein GS, Iglehart JD, Shi Q, Pardee AB. Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Molecular Cell. 38: 512-23. PMID 20513427 DOI: 10.1016/J.Molcel.2010.03.017  0.317
2010 Bakshi R, Hassan MQ, Pratap J, Lian JB, Montecino MA, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS. The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes. Journal of Cellular Physiology. 225: 569-76. PMID 20506188 DOI: 10.1002/Jcp.22240  0.465
2010 Gordon JA, Hassan MQ, Saini S, Montecino M, van Wijnen AJ, Stein GS, Stein JL, Lian JB. Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors. Molecular and Cellular Biology. 30: 3531-41. PMID 20439491 DOI: 10.1128/Mcb.00889-09  0.504
2010 Jeong JH, Jung YK, Kim HJ, Jin JS, Kim HN, Kang SM, Kim SY, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Kato S, Choi JY. The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues. Molecular and Cellular Biology. 30: 2365-75. PMID 20231365 DOI: 10.1128/Mcb.00672-09  0.457
2010 Han MS, Kim HJ, Wee HJ, Lim KE, Park NR, Bae SC, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Choi JY. The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta. Journal of Cellular Biochemistry. 110: 97-103. PMID 20225274 DOI: 10.1002/Jcb.22516  0.31
2010 Arriagada G, Henriquez B, Moena D, Merino P, Ruiz-Tagle C, Lian JB, Stein GS, Stein JL, Montecino M. Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts. The Journal of Steroid Biochemistry and Molecular Biology. 121: 156-8. PMID 20171279 DOI: 10.1016/J.Jsbmb.2010.02.013  0.37
2010 Ali SA, Zaidi SK, Dobson JR, Shakoori AR, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes. Proceedings of the National Academy of Sciences of the United States of America. 107: 4165-9. PMID 20160071 DOI: 10.1073/Pnas.1000620107  0.501
2010 Ling L, Murali S, Stein GS, Wijnen AJv, Cool SM. Glycosaminoglycans modulate RANKL-induced osteoclastogenesis. Journal of Cellular Biochemistry. 109: 1222-1231. PMID 20135643 DOI: 10.1002/Jcb.22506  0.366
2010 van der Deen M, Akech J, Wang T, FitzGerald TJ, Altieri DC, Languino LR, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells. Journal of Cellular Biochemistry. 109: 828-37. PMID 20082326 DOI: 10.1002/Jcb.22463  0.384
2010 Gaur T, Hussain S, Mudhasani R, Parulkar I, Colby JL, Frederick D, Kream BE, van Wijnen AJ, Stein JL, Stein GS, Jones SN, Lian JB. Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Developmental Biology. 340: 10-21. PMID 20079730 DOI: 10.1016/J.Ydbio.2010.01.008  0.37
2010 Dowdy CR, Xie R, Frederick D, Hussain S, Zaidi SK, Vradii D, Javed A, Li X, Jones SN, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation. Human Molecular Genetics. 19: 1048-57. PMID 20035012 DOI: 10.1093/Hmg/Ddp568  0.37
2010 Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene. 29: 811-21. PMID 19915614 DOI: 10.1038/Onc.2009.389  0.375
2010 Stein GS, Stein JL, Van Wijnen AJ, Lian JB, Montecino M, Croce CM, Choi JY, Ali SA, Pande S, Hassan MQ, Zaidi SK, Young DW. Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer. Advances in Enzyme Regulation. 50: 160-7. PMID 19896493 DOI: 10.1016/J.Advenzreg.2009.10.026  0.516
2010 Becker KA, Ghule PN, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells. Journal of Cellular Physiology. 222: 456-64. PMID 19890848 DOI: 10.1002/Jcp.21967  0.389
2010 Arriagada G, Paredes R, van Wijnen AJ, Lian JB, van Zundert B, Stein GS, Stein JL, Montecino M. 1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA. Journal of Cellular Physiology. 222: 336-46. PMID 19885846 DOI: 10.1002/Jcp.21958  0.365
2010 Becker KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming. Journal of Cellular Physiology. 222: 103-10. PMID 19774559 DOI: 10.1002/Jcp.21925  0.349
2010 Dowdy CR, Xie R, Frederick D, Zaidi SK, Jones SN, Lian JB, Wijnen AJv, Stein JL, Stein GS. An In Vivo role of Runx1 Subnuclear Targeting In Regulating the Gene Expression Program of Definitive Hematopoiesis Blood. 116: 3151-3151. DOI: 10.1182/Blood.V116.21.3151.3151  0.414
2010 Li J, Akech J, Pratap J, Wang T, FitzGerald TJ, Jiang Z, Violette SM, Hussain S, Stein GS, Lian JB, Languino LR. Abstract 2332: Alphavbeta6 integrin, a downstream effector of TGFbeta, promotes prostate cancer osteolytic lesions Cancer Research. 70: 2332-2332. DOI: 10.1158/1538-7445.Am10-2332  0.338
2009 Chi XZ, Kim J, Lee YH, Lee JW, Lee KS, Wee H, Kim WJ, Park WY, Oh BC, Stein GS, Ito Y, van Wijnen AJ, Bae SC. Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination. Cancer Research. 69: 8111-9. PMID 19808967 DOI: 10.1158/0008-5472.Can-09-1057  0.344
2009 Pereira BP, Zhou Y, Gupta A, Leong DT, Aung KZ, Ling L, Pho RW, Galindo M, Salto-Tellez M, Stein GS, Cool SM, van Wijnen AJ, Nathan SS. Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). Journal of Cellular Physiology. 221: 778-88. PMID 19746444 DOI: 10.1002/Jcp.21921  0.345
2009 San Martin IA, Varela N, Gaete M, Villegas K, Osorio M, Tapia JC, Antonelli M, Mancilla EE, Pereira BP, Nathan SS, Lian JB, Stein JL, Stein GS, van Wijnen AJ, Galindo M. Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells. Journal of Cellular Physiology. 221: 560-71. PMID 19739101 DOI: 10.1002/Jcp.21894  0.431
2009 Pratap J, Imbalzano KM, Underwood JM, Cohet N, Gokul K, Akech J, van Wijnen AJ, Stein JL, Imbalzano AN, Nickerson JA, Lian JB, Stein GS. Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression. Cancer Research. 69: 6807-14. PMID 19690135 DOI: 10.1158/0008-5472.Can-09-1471  0.389
2009 Zhang Y, Lian JB, Stein JL, Van Wijnen AJ, Stein GS. The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells Journal of Cellular Biochemistry. 108: 651-659. PMID 19670267 DOI: 10.1002/Jcb.22299  0.505
2009 Das K, Leong DT, Gupta A, Shen L, Putti T, Stein GS, van Wijnen AJ, Salto-Tellez M. Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer. European Journal of Cancer (Oxford, England : 1990). 45: 2239-48. PMID 19632824 DOI: 10.1016/J.Ejca.2009.06.021  0.305
2009 Xie R, Medina R, Zhang Y, Hussain S, Colby J, Ghule P, Sundararajan S, Keeler M, Liu LJ, van der Deen M, Mitra P, Lian JB, Rivera-Perez JA, Jones SN, Stein JL, ... ... Stein GS, et al. The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles. Proceedings of the National Academy of Sciences of the United States of America. 106: 12359-64. PMID 19590016 DOI: 10.1073/Pnas.0905651106  0.456
2009 Cruzat F, Henriquez B, Villagra A, Hepp M, Lian JB, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS, Montecino M. SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2. Biochemistry. 48: 7287-95. PMID 19545172 DOI: 10.1021/Bi9004792  0.479
2009 Wixted JJ, Fanning PJ, Gaur T, O'Connell SL, Silva J, Mason-Savas A, Ayers DC, Stein GS, Lian JB. Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: A novel role of the cysteinyl IL-1 receptor Journal of Cellular Physiology. 221: 31-39. PMID 19544365 DOI: 10.1002/Jcp.21809  0.329
2009 Altieri DC, Languino LR, Lian JB, Stein JL, Leav I, Wijnen AJv, Jiang Z, Stein GS. Prostate cancer regulatory networks. Journal of Cellular Biochemistry. 107: 845-852. PMID 19492418 DOI: 10.1002/Jcb.22162  0.335
2009 Haupt LM, Murali S, Mun FK, Teplyuk NM, Mei LF, Stein GS, Wijnen AJV, Nurcombe V, Cool SM. The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis. Journal of Cellular Physiology. 220: 780-791. PMID 19479939 DOI: 10.1002/Jcp.21825  0.396
2009 Filion TM, Qiao M, Ghule PN, Mandeville M, van Wijnen AJ, Stein JL, Lian JB, Altieri DC, Stein GS. Survival responses of human embryonic stem cells to DNA damage. Journal of Cellular Physiology. 220: 586-92. PMID 19373864 DOI: 10.1002/Jcp.21735  0.362
2009 Teplyuk NM, Zhang Y, Lou Y, Hawse JR, Hassan MQ, Teplyuk VI, Pratap J, Galindo M, Stein JL, Stein GS, Lian JB, van Wijnen AJ. The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts. Molecular Endocrinology (Baltimore, Md.). 23: 849-61. PMID 19342447 DOI: 10.1210/Me.2008-0270  0.431
2009 Li Z, Hassan MQ, Jafferji M, Aqeilan RI, Garzon R, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. The Journal of Biological Chemistry. 284: 15676-84. PMID 19342382 DOI: 10.1074/Jbc.M809787200  0.307
2009 Gaur T, Wixted JJ, Hussain S, O'Connell SL, Morgan EF, Ayers DC, Komm BS, Bodine PV, Stein GS, Lian JB. Secreted frizzled related protein 1 is a target to improve fracture healing. Journal of Cellular Physiology. 220: 174-81. PMID 19301255 DOI: 10.1002/Jcp.21747  0.331
2009 Ghule PN, Dominski Z, Lian JB, Stein JL, Van Wijnen AJ, Stein GS. The subnuclear organization of histone gene regulatory proteins and 3′ end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types Journal of Cellular Physiology. 220: 129-135. PMID 19277982 DOI: 10.1002/Jcp.21740  0.483
2009 Teplyuk NM, Haupt LM, Ling L, Dombrowski C, Foong KM, Nathan SS, Lian JB, Stein JL, Stein GS, Cool SM, Van Wijnen AJ. The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts Journal of Cellular Biochemistry. 107: 144-154. PMID 19259985 DOI: 10.1002/Jcb.22108  0.416
2009 Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer. Annals of the New York Academy of Sciences. 1155: 4-14. PMID 19250187 DOI: 10.1111/J.1749-6632.2009.03697.X  0.428
2009 Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Transcription-factor-mediated epigenetic control of cell fate and lineage commitment. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 1-6. PMID 19234518 DOI: 10.1139/O08-094  0.384
2009 Kuo YH, Zaidi SK, Gornostaeva S, Komori T, Stein GS, Castilla LH. Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice. Blood. 113: 3323-32. PMID 19179305 DOI: 10.1182/Blood-2008-06-162248  0.388
2009 Mitra P, Ghule PN, van der Deen M, Medina R, Xie RL, Holmes WF, Ye X, Nakayama KI, Harper JW, Stein JL, Stein GS, van Wijnen AJ. CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P. Journal of Cellular Physiology. 219: 438-48. PMID 19170105 DOI: 10.1002/Jcp.21687  0.367
2009 Lou Y, Javed A, Hussain S, Colby J, Frederick D, Pratap J, Xie R, Gaur T, van Wijnen AJ, Jones SN, Stein GS, Lian JB, Stein JL. A Runx2 threshold for the cleidocranial dysplasia phenotype. Human Molecular Genetics. 18: 556-68. PMID 19028669 DOI: 10.1093/Hmg/Ddn383  0.364
2009 Zhang Y, Hassan MQ, Xie R, Hawse JR, Spelsberg TC, Montecino MA, Stein JL, Lian JB, Wijnen AJV, Stein GS. Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats) Journal of Biological Chemistry. 284: 3125-3135. PMID 19017640 DOI: 10.1074/Jbc.M807466200  0.455
2009 Pande S, Ali SA, Dowdy CR, Zaidi SK, Ito K, Ito Y, Montecino MA, Lian JB, Stein JL, Wijnen AJV, Stein GS. Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes. Journal of Cellular Physiology. 218: 473-479. PMID 19006109 DOI: 10.1002/Jcp.21630  0.481
2009 Aqeilan RI, Hagan JP, de Bruin A, Rawahneh M, Salah Z, Gaudio E, Siddiqui H, Volinia S, Alder H, Lian JB, Stein GS, Croce CM. Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis. Endocrinology. 150: 1530-5. PMID 18974271 DOI: 10.1210/En.2008-1087  0.372
2009 Nathan SS, Pereira BP, Zhou YF, Gupta A, Dombrowski C, Soong R, Pho RW, Stein GS, Salto-Tellez M, Cool SM, van Wijnen AJ. Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma. Molecular Biology Reports. 36: 153-8. PMID 18931939 DOI: 10.1007/S11033-008-9378-1  0.426
2009 Stuardo M, Martinez M, Hidalgo K, Montecino M, Javed A, Lian JB, Stein GS, Stein JL, Gutiérrez SE. Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation Journal of Cellular Physiology. 218: 343-349. PMID 18853425 DOI: 10.1002/Jcp.21599  0.426
2009 Javed A, Afzal F, Bae J, Gutierrez SE, Zaidi K, Pratap J, Wijnen AJV, Stein JL, Stein GS, Lian JB. Specific Residues of RUNX2 Are Obligatory for Formation of BMP2-induced RUNX2-SMAD Complex to Promote Osteoblast Differentiation Cells Tissues Organs. 189: 133-137. PMID 18728344 DOI: 10.1159/000151719  0.383
2009 Hassan MQ, Saini S, Gordon JA, van Wijnen AJ, Montecino M, Stein JL, Stein GS, Lian JB. Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis. Cells, Tissues, Organs. 189: 122-5. PMID 18701816 DOI: 10.1159/000151453  0.471
2009 Song J, Xu J, Filion T, Saiz E, Tomsia AP, Lian JB, Stein GS, Ayers DC, Bertozzi CR. Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications. Journal of Biomedical Materials Research. Part A. 89: 1098-107. PMID 18546185 DOI: 10.1002/Jbm.A.32110  0.303
2009 Lian JB, Stein GS. Regulatory networks in the control of osteoblast cell fate are influenced by glucocorticoids Bone. 45. DOI: 10.1016/J.Bone.2009.07.024  0.306
2008 Bakshi R, Zaidi SK, Pande S, Hassan MQ, Young DW, Montecino M, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes. Journal of Cell Science. 121: 3981-90. PMID 19001502 DOI: 10.1242/Jcs.033431  0.446
2008 Ghule PN, Dominski Z, Yang XC, Marzluff WF, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 16964-9. PMID 18957539 DOI: 10.1073/Pnas.0809273105  0.449
2008 Medina R, Buck T, Zaidi SK, Miele-Chamberland A, Lian JB, Stein JL, Wijnen AJv, Stein GS. The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif Biochemistry. 47: 11415-11423. PMID 18850719 DOI: 10.1021/Bi800961D  0.472
2008 Pratap J, Wixted JJ, Gaur T, Zaidi SK, Dobson J, Gokul KD, Hussain S, Wijnen AJv, Stein JL, Stein GS, Lian JB. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Research. 68: 7795-7802. PMID 18829534 DOI: 10.1158/0008-5472.Can-08-1078  0.44
2008 Li Z, Hassan MQ, Volinia S, van Wijnen AJ, Stein JL, Croce CM, Lian JB, Stein GS. A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proceedings of the National Academy of Sciences of the United States of America. 105: 13906-11. PMID 18784367 DOI: 10.1073/Pnas.0804438105  0.33
2008 Zhang Y, Hassan MQ, Li ZY, Stein JL, Lian JB, Wijnen AJV, Stein GS. Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation Journal of Cellular Biochemistry. 105: 487-496. PMID 18655182 DOI: 10.1002/Jcb.21844  0.452
2008 Stein GS, Davie JR, Knowlton JR, Zaidi SK. Nuclear microenvironments and cancer. Journal of Cellular Biochemistry. 104: 1949-52. PMID 18649350 DOI: 10.1002/Jcb.21846  0.375
2008 Jeong JH, Jin JS, Kim HN, Kang SM, Liu JC, Lengner CJ, Otto F, Mundlos S, Stein JL, van Wijnen AJ, Lian JB, Stein GS, Choi JY. Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain. Journal of Cellular Physiology. 217: 511-7. PMID 18636555 DOI: 10.1002/Jcp.21524  0.375
2008 Teplyuk NM, Galindo M, Teplyuk VI, Pratap J, Young DW, Lapointe D, Javed A, Stein JL, Lian JB, Stein GS, van Wijnen AJ. Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors. The Journal of Biological Chemistry. 283: 27585-97. PMID 18625716 DOI: 10.1074/Jbc.M802453200  0.413
2008 Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer. Journal of Cellular Biochemistry. 104: 2016-26. PMID 18615590 DOI: 10.1002/Jcb.21813  0.361
2008 Trevant B, Gaur T, Hussain S, Symons J, Komm BS, Bodine PV, Stein GS, Lian JB. Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development. Journal of Cellular Physiology. 217: 113-26. PMID 18498122 DOI: 10.1002/Jcp.21482  0.391
2008 Aqeilan RI, Hassan MQ, de Bruin A, Hagan JP, Volinia S, Palumbo T, Hussain S, Lee SH, Gaur T, Stein GS, Lian JB, Croce CM. The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. The Journal of Biological Chemistry. 283: 21629-39. PMID 18487609 DOI: 10.1074/Jbc.M800855200  0.423
2008 Pockwinse SM, Zaidi SK, Medina RF, Bakshi R, Kota KP, Ali SA, Young DW, Nickerson JA, Javed A, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. In situ nuclear organization of regulatory machinery. Methods in Molecular Biology (Clifton, N.J.). 455: 239-59. PMID 18463823 DOI: 10.1007/978-1-59745-104-8_17  0.348
2008 van der Deen M, Hassan MQ, Pratap J, Teplyuk NM, Young DW, Javed A, Zaidi SK, Lian JB, Montecino M, Stein JL, Stein GS, van Wijnen AJ. Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells. Methods in Molecular Biology (Clifton, N.J.). 455: 165-76. PMID 18463819 DOI: 10.1007/978-1-59745-104-8_13  0.491
2008 Ali SA, Zaidi SK, Dacwag CS, Salma N, Young DW, Shakoori AR, Montecino MA, Lian JB, van Wijnen AJ, Imbalzano AN, Stein GS, Stein JL. Phenotypic transcription factors epigenetically mediate cell growth control. Proceedings of the National Academy of Sciences of the United States of America. 105: 6632-7. PMID 18445650 DOI: 10.1073/Pnas.0800970105  0.458
2008 Hall LL, Byron M, Butler J, Becker KA, Nelson A, Amit M, Itskovitz-Eldor J, Stein J, Stein G, Ware C, Lawrence JB. X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected. Journal of Cellular Physiology. 216: 445-52. PMID 18340642 DOI: 10.1002/Jcp.21411  0.32
2008 Montecino MA, Stein GS, Stein JL, Lian JB, Wijnen AJV, Carvallo L, Marcellini S, Cruzat F, Arriagada G. Vitamin d control of gene expression: temporal and spatial parameters for organization of the regulatory machinery Critical Reviews in Eukaryotic Gene Expression. 18: 163-172. PMID 18304030 DOI: 10.1615/Critreveukargeneexpr.V18.I2.50  0.369
2008 Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, ... ... Stein G, et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. The Journal of Clinical Investigation. 118: 491-504. PMID 18219387 DOI: 10.1172/Jci33102  0.361
2008 Javed A, Bae JS, Afzal F, Gutierrez S, Pratap J, Zaidi SK, Lou Y, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. The Journal of Biological Chemistry. 283: 8412-22. PMID 18204048 DOI: 10.1074/Jbc.M705578200  0.393
2008 Jensen ED, Niu L, Caretti G, Nicol SM, Teplyuk N, Stein GS, Sartorelli V, van Wijnen AJ, Fuller-Pace FV, Westendorf JJ. p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation. Journal of Cellular Biochemistry. 103: 1438-51. PMID 17960593 DOI: 10.1002/Jcb.21526  0.419
2008 Li S, Tu Q, Zhang J, Stein G, Lian J, Yang PS, Chen J. Systemically transplanted bone marrow stromal cells contributing to bone tissue regeneration. Journal of Cellular Physiology. 215: 204-9. PMID 17960569 DOI: 10.1002/Jcp.21302  0.319
2008 Carvallo L, Henriquez B, Paredes R, Olate J, Onate S, Wijnen AJV, Lian JB, Stein GS, Stein JL, Montecino MA. 1α,25‐dihydroxy vitamin D3‐enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1α,25‐dihydroxy vitamin D3 receptor‐SRC‐1 coactivator complex Journal of Cellular Physiology. 214: 740-749. PMID 17786964 DOI: 10.1002/Jcp.21267  0.416
2008 George KL, Saltman LH, Stein GS, Lian JB, Zurier RB. Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells Journal of Cellular Physiology. 214: 714-720. PMID 17786950 DOI: 10.1002/Jcp.21263  0.334
2008 Montecino M, Stein JL, Stein GS, Lian JB, van Wijnen AJ, Cruzat F, Gutiérrez S, Olate J, Marcellini S, Gutiérrez JL. Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 85: 419-25. PMID 17713577 DOI: 10.1139/O07-070  0.344
2007 Stein GS. Gene Expression in Nuclear Microenvironments for Biological Control and Cancer Cancer Biology & Therapy. 6: 1817-1821. PMID 18441529 DOI: 10.4161/Cbt.6.11.5294  0.397
2007 Zaidi SK, Pande S, Pratap J, Gaur T, Grigoriu SR, Ali SA, Stein JL, Lian JB, Wijnen AJV, Stein GS. Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential Proceedings of the National Academy of Sciences of the United States of America. 104: 19861-19866. PMID 18077419 DOI: 10.1073/Pnas.0709650104  0.418
2007 Medina R, Deen MVD, Miele-Chamberland A, Xie RL, Wijnen AJV, Stein JL, Stein GS. The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes Cancer Research. 67: 10334-10342. PMID 17974976 DOI: 10.1158/0008-5472.Can-07-1560  0.434
2007 Galindo M, Kahler RA, Teplyuk NM, Stein JL, Lian JB, Stein GS, Westendorf JJ, van Wijnen AJ. Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts. Journal of Molecular Histology. 38: 501-6. PMID 17885813 DOI: 10.1007/S10735-007-9143-0  0.462
2007 Xie RL, Liu L, Mitra P, Stein JL, Wijnen AJv, Stein GS. Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition. Gene. 402: 94-102. PMID 17826007 DOI: 10.1016/J.Gene.2007.07.027  0.371
2007 Miele A, Medina RF, Wijnen AJV, Stein GS, Stein JL. The interactome of the histone gene regulatory factor HiNF‐P suggests novel cell cycle related roles in transcriptional control and RNA processing Journal of Cellular Biochemistry. 102: 136-148. PMID 17577209 DOI: 10.1002/Jcb.21284  0.463
2007 Zaidi SK, Young DW, Javed A, Pratap J, Montecino M, van Wijnen A, Lian JB, Stein JL, Stein GS. Nuclear microenvironments in biological control and cancer. Nature Reviews. Cancer. 7: 454-63. PMID 17522714 DOI: 10.1038/Nrc2149  0.374
2007 Ghule PN, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells. Journal of Cellular Physiology. 213: 9-17. PMID 17520687 DOI: 10.1002/Jcp.21119  0.453
2007 Yeh N, Miller JP, Gaur T, Capellini TD, Nikolich-Zugich J, de la Hoz C, Selleri L, Bromage TG, van Wijnen AJ, Stein GS, Lian JB, Vidal A, Koff A. Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130. Molecular and Cellular Biology. 27: 5161-71. PMID 17502351 DOI: 10.1128/Mcb.02431-06  0.324
2007 Arriagada G, Paredes R, Olate J, Wijnen AJV, Lian JB, Stein GS, Stein JL, Onate S, Montecino MA. Phosphorylation at serine 208 of the 1α,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators The Journal of Steroid Biochemistry and Molecular Biology. 103: 425-429. PMID 17368182 DOI: 10.1016/J.Jsbmb.2006.12.021  0.323
2007 Stein GS, Lian JB, Wijnen AJV, Stein JL, Javed A, Montecino MA, Choi J, Vradii D, Zaidi SK, Pratap J, Young DW. Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer Advances in Enzyme Regulation. 47: 242-250. PMID 17363043 DOI: 10.1016/J.Advenzreg.2006.12.014  0.509
2007 Young DW, Hassan MQ, Yang XQ, Galindo M, Javed A, Zaidi SK, Furcinitti P, Lapointe D, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. Proceedings of the National Academy of Sciences of the United States of America. 104: 3189-94. PMID 17360627 DOI: 10.1073/Pnas.0611419104  0.517
2007 Aqeilan RI, Trapasso F, Hussain S, Costinean S, Marshall D, Pekarsky Y, Hagan JP, Zanesi N, Kaou M, Stein GS, Lian JB, Croce CM. Targeted deletion of Wwox reveals a tumor suppressor function. Proceedings of the National Academy of Sciences of the United States of America. 104: 3949-54. PMID 17360458 DOI: 10.1073/Pnas.0609783104  0.303
2007 Hassan MQ, Tare R, Lee SH, Mandeville M, Weiner B, Montecino M, van Wijnen AJ, Stein JL, Stein GS, Lian JB. HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes. Molecular and Cellular Biology. 27: 3337-52. PMID 17325044 DOI: 10.1128/Mcb.01544-06  0.472
2007 Montecino MA, Stein GS, Cruzat F, Marcellini S, Stein JL, Lian JB, Wijnen AJV, Arriagada G. An architectural perspective of vitamin D responsiveness. Archives of Biochemistry and Biophysics. 460: 293-299. PMID 17288986 DOI: 10.1016/J.Abb.2006.12.015  0.354
2007 Gutiérrez J, Paredes R, Cruzat F, Hill DA, Van Wijnen AJ, Lian JB, Stein GS, Stein JL, Imbalzano AN, Montecino M. Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter Journal of Biological Chemistry. 282: 9445-9457. PMID 17272279 DOI: 10.1074/Jbc.M609847200  0.462
2007 Young DW, Hassan MQ, Pratap J, Galindo M, Zaidi SK, Lee SH, Yang X, Xie R, Javed A, Underwood JM, Furcinitti P, Imbalzano AN, Penman S, Nickerson JA, Montecino MA, ... ... Stein GS, et al. Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature. 445: 442-6. PMID 17251981 DOI: 10.1038/Nature05473  0.452
2007 Bruna C, Arriagada G, Lian JB, Stein GS, Bunster M, Martinez-Oyanedel J, Montecino MA. Crystallization and preliminary X-ray analysis of a domain in the Runx2 transcription factor that interacts with the 1α,25 dihydroxy vitamin D3 receptor Journal of Cellular Biochemistry. 101: 785-789. PMID 17226779 DOI: 10.1002/Jcb.21231  0.341
2007 Carvallo L, Henriquez B, Olate J, Wijnen AJV, Lian JB, Stein GS, Onate S, Stein JL, Montecino MA. The 1α,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene The Journal of Steroid Biochemistry and Molecular Biology. 103: 420-424. PMID 17218095 DOI: 10.1016/J.Jsbmb.2006.12.022  0.414
2007 Rajgopal A, Young DW, Mujeeb KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells. Journal of Cellular Biochemistry. 100: 1509-17. PMID 17171635 DOI: 10.1002/Jcb.21137  0.394
2007 Mitra P, Xie R, Harper JW, Stein JL, Stein GS, Wijnen AJv. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription Journal of Cellular Biochemistry. 101: 181-191. PMID 17163457 DOI: 10.1002/Jcb.21157  0.469
2007 Becker KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells. Journal of Cellular Physiology. 210: 517-26. PMID 17096384 DOI: 10.1002/Jcp.20903  0.507
2007 Jackson RA, Murali S, van Wijnen AJ, Stein GS, Nurcombe V, Cool SM. Heparan sulfate regulates the anabolic activity of MC3T3-E1 preosteoblast cells by induction of Runx2. Journal of Cellular Physiology. 210: 38-50. PMID 17051597 DOI: 10.1002/Jcp.20813  0.412
2007 Bae J, Gutierrez SE, Narla R, Pratap J, Devados R, Wijnen AJV, Stein JL, Stein GS, Lian JB, Javed A. Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation. Journal of Cellular Biochemistry. 100: 434-449. PMID 16927309 DOI: 10.1002/Jcb.21039  0.454
2006 Medina R, Van Wijnen AJ, Stein GS, Stein JL. The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT Biochemistry. 45: 15915-15920. PMID 17176114 DOI: 10.1021/Bi061425M  0.433
2006 Pratap J, Lian JB, Javed A, Barnes GL, van Wijnen AJ, Stein JL, Stein GS. Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone. Cancer Metastasis Reviews. 25: 589-600. PMID 17165130 DOI: 10.1007/S10555-006-9032-0  0.454
2006 Hassan MQ, Tare RS, Lee SH, Mandeville M, Morasso MI, Javed A, van Wijnen AJ, Stein JL, Stein GS, Lian JB. BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network. The Journal of Biological Chemistry. 281: 40515-26. PMID 17060321 DOI: 10.1074/Jbc.M604508200  0.494
2006 Lian JB, Stein GS, Javed A, van Wijnen AJ, Stein JL, Montecino M, Hassan MQ, Gaur T, Lengner CJ, Young DW. Networks and hubs for the transcriptional control of osteoblastogenesis. Reviews in Endocrine & Metabolic Disorders. 7: 1-16. PMID 17051438 DOI: 10.1007/S11154-006-9001-5  0.475
2006 Stein GS, Wijnen AJV, Stein JL, Lian JB, Montecino MA, Zaidi SK, Braastad CD. An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition. Journal of Cellular Physiology. 209: 706-710. PMID 17001681 DOI: 10.1002/Jcp.20843  0.441
2006 Zaidi SK, Javed A, Pratap J, Schroeder TM, J Westendorf J, Lian JB, van Wijnen AJ, Stein GS, Stein JL. Alterations in intranuclear localization of Runx2 affect biological activity. Journal of Cellular Physiology. 209: 935-42. PMID 16972259 DOI: 10.1002/Jcp.20791  0.402
2006 Becker KA, Ghule PN, Therrien JA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. Journal of Cellular Physiology. 209: 883-93. PMID 16972248 DOI: 10.1002/Jcp.20776  0.364
2006 Ling L, Murali S, Dombrowski C, Haupt LM, Stein GS, Van Wijnen AJ, Nurcombe V, Cool SM. Sulfated glycosaminoglycans mediate the effects of FGF2 on the osteogenic potential of rat calvarial osteoprogenitor cells Journal of Cellular Physiology. 209: 811-825. PMID 16972247 DOI: 10.1002/Jcp.20760  0.379
2006 Villagra A, Cruzat F, Carvallo L, Paredes R, Olate J, van Wijnen AJ, Stein GS, Lian JB, Stein JL, Imbalzano AN, Montecino M. Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity. The Journal of Biological Chemistry. 281: 22695-706. PMID 16772287 DOI: 10.1074/Jbc.M511640200  0.47
2006 Gaur T, Rich L, Lengner CJ, Hussain S, Trevant B, Ayers DC, Stein JL, Bodine PVN, Komm BS, Stein GS, Lian JB. Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation. Journal of Cellular Physiology. 208: 87-96. PMID 16575902 DOI: 10.1002/Jcp.20637  0.42
2006 Lengner CJ, Steinman HA, Gagnon J, Smith TW, Henderson JE, Kream BE, Stein GS, Lian JB, Jones SN. Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. The Journal of Cell Biology. 172: 909-21. PMID 16533949 DOI: 10.1083/Jcb.200508130  0.38
2006 Kim HJ, Nam SH, Kim HJ, Park HS, Ryoo HM, Kim SY, Cho TJ, Kim SG, Bae SC, Kim IS, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Choi JY. Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype. Journal of Cellular Physiology. 207: 114-22. PMID 16270353 DOI: 10.1002/Jcp.20552  0.327
2006 Kahler RA, Galindo M, Lian J, Stein GS, van Wijnen AJ, Westendorf JJ. Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts. Journal of Cellular Biochemistry. 97: 969-83. PMID 16267835 DOI: 10.1002/Jcb.20702  0.491
2006 Pockwinse SM, Rajgopal A, Young DW, Mujeeb KA, Nickerson J, Javed A, Redick S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Doxsey SJ. Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2. Journal of Cellular Physiology. 206: 354-62. PMID 16110492 DOI: 10.1002/Jcp.20469  0.414
2006 Vradii D, Wagner S, Doan DN, Nickerson JA, Montecino M, Lian JB, Stein JL, Van Wijnen AJ, Imbalzano AN, Stein GS. Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes Journal of Cellular Physiology. 206: 112-118. PMID 15965950 DOI: 10.1002/Jcp.20432  0.43
2005 Kim YJ, Kim HN, Park EK, Lee BH, Ryoo HM, Kim SY, Kim IS, Stein JL, Lian JB, Stein GS, van Wijnen AJ, Choi JY. The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells. Gene. 366: 145-51. PMID 16314050 DOI: 10.1016/J.Gene.2005.08.021  0.45
2005 Pratap J, Javed A, Languino LR, Wijnen AJv, Stein JL, Stein GS, Lian JB. The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion Molecular and Cellular Biology. 25: 8581-8591. PMID 16166639 DOI: 10.1128/Mcb.25.19.8581-8591.2005  0.389
2005 Bodine PVN, Billiard J, Moran RA, Ponce-De-Leon H, McLarney S, Mangine A, Scrimo MJ, Bhat RA, Stauffer B, Green J, Stein GS, Lian JB, Komm BS. The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis Journal of Cellular Biochemistry. 96: 1212-1230. PMID 16149051 DOI: 10.1002/Jcb.20599  0.41
2005 Li X, Vradii D, Gutierrez SEu, Lian JB, Wijnen AJV, Stein JL, Stein GS, Javed A. Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1. Journal of Cellular Biochemistry. 96: 795-809. PMID 16149049 DOI: 10.1002/Jcb.20548  0.409
2005 Stein GS, Lian JB, Stein JL, van Wijnen AJ, Javed A, Montecino M, Zaidi SK, Young DW, Choi JY, Pratap J. Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer. Advances in Enzyme Regulation. 45: 136-54. PMID 16135382 DOI: 10.1016/J.Advenzreg.2005.02.009  0.453
2005 Holmes WF, Braastad CD, Mitra P, Hampe C, Doenecke D, Albig W, Stein JL, Wijnen AJv, Stein GS. Coordinate Control and Selective Expression of the Full Complement of Replication-dependent Histone H4 Genes in Normal and Cancer Cells Journal of Biological Chemistry. 280: 37400-37407. PMID 16131487 DOI: 10.1074/Jbc.M506995200  0.454
2005 Gaur T, Lengner CJ, Hovhannisyan H, Bhat RA, Bodine PVN, Komm BS, Javed A, Wijnen AJv, Stein JL, Stein GS, Lian JB. Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression Journal of Biological Chemistry. 280: 33132-33140. PMID 16043491 DOI: 10.1074/Jbc.M500608200  0.437
2005 Miele A, Braastad CD, Holmes WF, Mitra P, Medina RF, Xie R, Zaidi SK, Ye X, Wei Y, Harper JW, Wijnen AJV, Stein JL, Stein GS. HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Molecular and Cellular Biology. 25: 6140-6153. PMID 15988025 DOI: 10.1128/Mcb.25.14.6140-6153.2005  0.401
2005 Vradii D, Zaidi SK, Lian JB, Van Wijnen AJ, Stein JL, Stein GS. Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype Proceedings of the National Academy of Sciences of the United States of America. 102: 7174-7179. PMID 15870195 DOI: 10.1073/Pnas.0502130102  0.37
2005 Saltman LH, Javed A, Ribadeneyra J, Hussain S, Young DW, Osdoby P, Amcheslavsky A, van Wijnen AJ, Stein JL, Stein GS, Lian JB, Bar-Shavit Z. Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1. Journal of Cellular Physiology. 204: 871-80. PMID 15828028 DOI: 10.1002/Jcp.20329  0.47
2005 Stein GS. Mechanogenomic control of DNA exposure and sequestration. American Journal of Pathology. 166: 959-962. PMID 15793277 DOI: 10.1016/S0002-9440(10)62317-6  0.401
2005 Galindo M, Pratap J, Young DW, Hovhannisyan H, Im HJ, Choi JY, Lian JB, Stein JL, Stein GS, van Wijnen AJ. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. The Journal of Biological Chemistry. 280: 20274-85. PMID 15781466 DOI: 10.1074/Jbc.M413665200  0.424
2005 Lengner CJ, Hassan MQ, Serra RW, Lepper C, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation. The Journal of Biological Chemistry. 280: 15872-9. PMID 15703179 DOI: 10.1074/Jbc.M411144200  0.503
2005 Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, van Wijnen AJ, Lian JB, Stein GS. The dynamic organization of gene-regulatory machinery in nuclear microenvironments. Embo Reports. 6: 128-33. PMID 15689940 DOI: 10.1038/Sj.Embor.7400337  0.452
2005 Javed A, Barnes GL, Pratap J, Antkowiak T, Gerstenfeld LC, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 1454-9. PMID 15665096 DOI: 10.1073/Pnas.0409121102  0.419
2005 Afzal F, Pratap J, Ito K, Ito Y, Stein JL, Wijnen AJv, Stein GS, Lian JB, Javed A. Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. Journal of Cellular Physiology. 204: 63-72. PMID 15573378 DOI: 10.1002/Jcp.20258  0.376
2005 Young DW, Pratap J, Javed A, Weiner B, Ohkawa Y, van Wijnen A, Montecino M, Stein GS, Stein JL, Imbalzano AN, Lian JB. SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation. Journal of Cellular Biochemistry. 94: 720-30. PMID 15565649 DOI: 10.1002/Jcb.20332  0.487
2005 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'Keefe RJ, Stein GS, Drissi MH. Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. Journal of Cellular Physiology. 203: 133-43. PMID 15389629 DOI: 10.1002/Jcp.20210  0.436
2004 Yunker LA, Undersander A, Lian JB, Stein GS, Carlson CS, Mauro LJ. The tyrosine phosphatase, OST-PTP, is expressed in mesenchymal progenitor cells early during skeletogenesis in the mouse. Journal of Cellular Biochemistry. 93: 761-73. PMID 15660420 DOI: 10.1002/Jcb.20183  0.457
2004 Braastad CD, Hovhannisyan H, Wijnen AJv, Stein JL, Stein GS. Functional characterization of a human histone gene cluster duplication Gene. 342: 35-40. PMID 15527963 DOI: 10.1016/J.Gene.2004.07.036  0.422
2004 Hassan MQ, Javed A, Morasso MI, Karlin J, Montecino M, van Wijnen AJ, Stein GS, Stein JL, Lian JB. Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene. Molecular and Cellular Biology. 24: 9248-61. PMID 15456894 DOI: 10.1128/Mcb.24.20.9248-9261.2004  0.509
2004 Paredes R, Arriagada G, Cruzat F, Villagra A, Olate J, Zaidi K, Wijnen AJV, Lian JB, Stein GS, Stein JL, Montecino MA. Bone-Specific Transcription Factor Runx2 Interacts with the 1α,25-Dihydroxyvitamin D3 Receptor To Up-Regulate Rat Osteocalcin Gene Expression in Osteoblastic Cells Molecular and Cellular Biology. 24: 8847-8861. PMID 15456860 DOI: 10.1128/Mcb.24.20.8847-8861.2004  0.452
2004 Young DW, Zaidi SK, Furcinitti PS, Javed A, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Quantitative signature for architectural organization of regulatory factors using intranuclear informatics. Journal of Cell Science. 117: 4889-96. PMID 15367579 DOI: 10.1242/Jcs.01229  0.371
2004 Gutierrez S, Liu J, Javed A, Montecino M, Stein GS, Lian JB, Stein JL. The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain Journal of Biological Chemistry. 279: 43581-43588. PMID 15299011 DOI: 10.1074/Jbc.M408335200  0.411
2004 Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Intranuclear trafficking: organization and assembly of regulatory machinery for combinatorial biological control. The Journal of Biological Chemistry. 279: 43363-6. PMID 15277516 DOI: 10.1074/Jbc.R400020200  0.417
2004 Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction. Methods in Molecular Biology (Clifton, N.J.). 285: 63-7. PMID 15269399 DOI: 10.1385/1-59259-822-6:063  0.326
2004 Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion. Methods in Molecular Biology (Clifton, N.J.). 285: 57-62. PMID 15269398 DOI: 10.1385/1-59259-822-6:057  0.353
2004 Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay. Methods in Molecular Biology (Clifton, N.J.). 285: 45-55. PMID 15269397 DOI: 10.1385/1-59259-822-6:045  0.348
2004 Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Analysis of in vivo gene expression using epitope-tagged proteins. Methods in Molecular Biology (Clifton, N.J.). 285: 37-40. PMID 15269395 DOI: 10.1385/1-59259-822-6:037  0.377
2004 Lengner CJ, Lepper C, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Primary mouse embryonic fibroblasts: a model of mesenchymal cartilage formation. Journal of Cellular Physiology. 200: 327-33. PMID 15254959 DOI: 10.1002/Jcp.20118  0.408
2004 Barnes GL, Hebert KE, Kamal M, Javed A, Einhorn TA, Lian JB, Stein GS, Gerstenfeld LC. Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease. Cancer Research. 64: 4506-13. PMID 15231660 DOI: 10.1158/0008-5472.Can-03-3851  0.398
2004 Paredes R, Arriagada G, Cruzat F, Olate J, Wijnen AV, Lian J, Stein G, Stein J, Montecino M. The Runx2 transcription factor plays a key role in the 1α,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells ☆ The Journal of Steroid Biochemistry and Molecular Biology. 89: 269-271. PMID 15225783 DOI: 10.1016/J.Jsbmb.2004.03.076  0.395
2004 Stein GS, Lian JB, van Wijnen AJ, Stein JL, Montecino M, Javed A, Zaidi SK, Young DW, Choi JY, Pockwinse SM. Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene. 23: 4315-29. PMID 15156188 DOI: 10.1038/Sj.Onc.1207676  0.435
2004 van Wijnen AJ, Stein GS, Gergen JP, Groner Y, Hiebert SW, Ito Y, Liu P, Neil JC, Ohki M, Speck N. Nomenclature for Runt-related (RUNX) proteins. Oncogene. 23: 4209-10. PMID 15156174 DOI: 10.1038/Sj.Onc.1207758  0.371
2004 Lian JB, Javed A, Zaidi SK, Lengner C, Montecino M, van Wijnen AJ, Stein JL, Stein GS. Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors. Critical Reviews in Eukaryotic Gene Expression. 14: 1-41. PMID 15104525  0.403
2004 Bodine PV, Zhao W, Kharode YP, Bex FJ, Lambert AJ, Goad MB, Gaur T, Stein GS, Lian JB, Komm BS. The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice. Molecular Endocrinology (Baltimore, Md.). 18: 1222-37. PMID 14976225 DOI: 10.1210/Me.2003-0498  0.327
2004 Zaidi SK, Sullivan AJ, Medina R, Ito Y, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. The Embo Journal. 23: 790-9. PMID 14765127 DOI: 10.1038/Sj.Emboj.7600073  0.429
2004 Stein GS, Lian JB, Wijnen AJV, Stein JL, Javed A, Montecino M, Zaidi SK, Young D, Choi JY, Gutierrez S, Pockwinse S. Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation. Journal of Cellular Biochemistry. 91: 287-302. PMID 14743389 DOI: 10.1002/Jcb.10777  0.451
2004 Stein GS, Lian JB, Stein JL, van Wijnen AJ, Choi JY, Pratap J, Zaidi SK. Temporal and spatial parameters of skeletal gene expression: targeting RUNX factors and their coregulatory proteins to subnuclear domains. Connective Tissue Research. 149-53. PMID 12952189  0.338
2004 Lian JB, Stein JL, Stein GS, van Wijnen AJ, Montecino M, Javed A, Gutierrez S, Shen J, Zaidi SK, Drissi H. Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions. Connective Tissue Research. 141-8. PMID 12952188  0.401
2004 Stein GS, Stein JL, Lian JB, Wijnen AJV, Montecino MA, Javed A, Zaidi SK, Young DW, Choi J, Pockwinse SM. Nuclear microenvironments: an architectural platform for the convergence and integration of transcriptional regulatory signals. European Journal of Histochemistry. 48: 65-76. DOI: 10.4081/860  0.444
2004 Lian JB, Javed A, Zaidi SK, Lengner C, Montecino M, Wijnen AJV, Stein JL, Stein GS. Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors Critical Reviews in Eukaryotic Gene Expression. 14: 1-41. DOI: 10.1615/Critreveukaryotgeneexpr.V14.I12.10  0.502
2003 Zaidi SK, Young DW, Pockwinse SM, Javed A, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 14852-7. PMID 14657346 DOI: 10.1073/Pnas.2533076100  0.453
2003 Kim JO, Kim HN, Hwang MH, Shin HI, Kim SY, Park RW, Park EY, Kim IS, Wijnen AJv, Stein JL, Lian JB, Stein GS, Choi JY. Differential gene expression analysis using paraffin-embedded tissues after laser microdissection. Journal of Cellular Biochemistry. 90: 998-1006. PMID 14624459 DOI: 10.1002/Jcb.10680  0.363
2003 Mitra P, Xie RL, Medina R, Hovhannisyan H, Zaidi SK, Wei Y, Harper JW, Stein JL, Wijnen AJV, Stein GS. Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase Molecular and Cellular Biology. 23: 8110-8123. PMID 14585971 DOI: 10.1128/Mcb.23.22.8110-8123.2003  0.424
2003 Stein GS, Zaidi SK, Braastad CD, Montecino MA, Wijnen AJV, Choi J, Stein JL, Lian JB, Javed A. Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair. Trends in Cell Biology. 13: 584-592. PMID 14573352 DOI: 10.1016/J.Tcb.2003.09.009  0.388
2003 Lian JB, Stein GS. The temporal and spatial subnuclear organization of skeletal gene regulatory machinery: Integrating multiple levels of transcriptional control Calcified Tissue International. 72: 631-637. PMID 14562989 DOI: 10.1007/S00223-002-1058-X  0.346
2003 Lian JB, Stein GS. Runx2/Cbfa1: A multifunctional regulator of bone formation Current Pharmaceutical Design. 9: 2677-2685. PMID 14529540 DOI: 10.2174/1381612033453659  0.437
2003 Pratap J, Galindo M, Zaidi SK, Vradii D, Bhat BM, Robinson JA, Choi JY, Komori T, Stein JL, Lian JB, Stein GS, van Wijnen AJ. Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts. Cancer Research. 63: 5357-62. PMID 14500368  0.353
2003 Stein GS, Lian JB, Montecino M, Stein JL, Wijnen AJv, Javed A, Pratap J, Choi J, Zaidi SK, Gutierrez S, Harrington K, Shen J, Young D, Pockwinse S. Nuclear microenvironments support physiological control of gene expression. Chromosome Research. 11: 527-536. PMID 12971727 DOI: 10.1023/A:1024943214431  0.446
2003 Gupta S, Luong MX, Bleuming SA, Miele A, Luong M, Young D, Knudsen ES, Van Wijnen AJ, Stein JL, Stein GS. Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription. Journal of Cellular Physiology. 196: 541-56. PMID 12891711 DOI: 10.1002/Jcp.10335  0.455
2003 Zhang C, Dowd DR, Staal A, Gu C, Lian JB, van Wijnen AJ, Stein GS, MacDonald PN. Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing. The Journal of Biological Chemistry. 278: 35325-36. PMID 12840015 DOI: 10.1074/Jbc.M305191200  0.411
2003 Lian JB, Balint E, Javed A, Drissi H, Vitti R, Quinlan EJ, Zhang L, Wijnen AJV, Stein JL, Speck NA, Stein GS. Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo. Journal of Cellular Physiology. 196: 301-311. PMID 12811823 DOI: 10.1002/Jcp.10316  0.407
2003 Barnes GL, Javed A, Waller SM, Kamal MH, Hebert KE, Hassan MQ, Bellahcene A, Van Wijnen AJ, Young MF, Lian JB, Stein GS, Gerstenfeld LC. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Research. 63: 2631-7. PMID 12750290  0.307
2003 Xie RL, Gupta S, Miele A, Shiffman D, Stein JL, Stein GS, Wijnen AJV. The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter Journal of Biological Chemistry. 278: 26589-26596. PMID 12732645 DOI: 10.1074/Jbc.M301491200  0.441
2003 Stein GS, Lian JB, Stein JL, Wijnen AJv, Montecino M, Pratap J, Choi Je, Zaidi SK, Javed A, Gutierrez S, Harrington K, Shen J, Young D. Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer. Blood Cells Molecules and Diseases. 30: 170-176. PMID 12732180 DOI: 10.1016/S1079-9796(03)00029-9  0.464
2003 Balint E, Lapointe D, Drissi H, van der Meijden C, Young DW, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation. Journal of Cellular Biochemistry. 89: 401-26. PMID 12704803 DOI: 10.1002/Jcb.10515  0.479
2003 Sierra J, Villagra A, Paredes R, Cruzat F, Gutierrez S, Javed A, Arriagada G, Olate J, Imschenetzky M, Van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity. Molecular and Cellular Biology. 23: 3339-51. PMID 12697832 DOI: 10.1128/Mcb.23.9.3339-3351.2003  0.418
2003 Hovhannisyan H, Cho B, Mitra P, Montecino M, Stein GS, Van Wijnen AJ, Stein JL. Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells. Molecular and Cellular Biology. 23: 1460-9. PMID 12556504 DOI: 10.1128/Mcb.23.4.1460-1469.2003  0.513
2003 Shen J, Hovhannisyan H, Lian JB, Montecino MA, Stein GS, Stein JL, Wijnen AJv. Transcriptional Induction of the Osteocalcin Gene During Osteoblast Differentiation Involves Acetylation of Histones H3 and H4 Molecular Endocrinology. 17: 743-756. PMID 12554783 DOI: 10.1210/Me.2002-0122  0.464
2003 Stein GS, Lian JB, Stein JL, Wijnen AJv, Montecino M, Javed A, Pratap J, Choi J, Zaidi SK, Gutierrez S, Harrington K, Shen J, Young D. Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression. Journal of Cellular Biochemistry. 88: 340-355. PMID 12520536 DOI: 10.1002/Jcb.10364  0.451
2003 Stein GS, Lian JB, Stein JL, Wijnen AJv, Choi JY, Pratap J, Zaidi SK. Temporal and Spatial Parameters of Skeletal Gene Expression: Targeting RUNX Factors and their Coregulatory Proteins to Subnuclear Domains Connective Tissue Research. 44: 149-153. DOI: 10.1080/03008900390152241  0.438
2003 Lian JB, Stein JL, Stein GS, Wijnen AJv, Montecino M, Javed A, Gutierrez S, Shen J, Zaidi SK, Drissi H. Runx2/Cbfa1 Functions: Diverse Regulation of Gene Transcription by Chromatin Remodeling and Co-Regulatory Protein Interactions Connective Tissue Research. 44: 141-148. DOI: 10.1080/03008200390152232  0.495
2003 Balint E, Lapointe D, Drissi H, Meijden CVd, Young DW, Wijnen AJV, Stein JL, Stein GS, Lian JB. Erratum: Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP-2-mediated osteoblast differentiation. (Journal of Cellular Biochemistry (89)(401-426)) Journal of Cellular Biochemistry. 89. DOI: 10.1002/Jcb.10598  0.36
2002 Kundu M, Javed A, Jeon JP, Horner A, Shum L, Eckhaus M, Muenke M, Lian JB, Yang Y, Nuckolls GH, Stein GS, Liu PP. Cbfbeta interacts with Runx2 and has a critical role in bone development. Nature Genetics. 32: 639-44. PMID 12434156 DOI: 10.1038/Ng1050  0.373
2002 Miller J, Horner A, Stacy T, Lowrey C, Lian JB, Stein G, Nuckolls GH, Speck NA. The core-binding factor beta subunit is required for bone formation and hematopoietic maturation. Nature Genetics. 32: 645-9. PMID 12434155 DOI: 10.1038/Ng1049  0.313
2002 Barseguian K, Lutterbach B, Hiebert SW, Nickerson J, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins. Proceedings of the National Academy of Sciences of the United States of America. 99: 15434-9. PMID 12427969 DOI: 10.1073/Pnas.242588499  0.368
2002 Westendorf JJ, Zaidi SK, Cascino JE, Kahler R, van Wijnen AJ, Lian JB, Yoshida M, Stein GS, Li X. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Molecular and Cellular Biology. 22: 7982-92. PMID 12391164 DOI: 10.1128/Mcb.22.22.7982-7992.2002  0.438
2002 Harrington KS, Javed A, Drissi H, McNeil SM, Lian JB, Stein JL, Wijnen AJV, Wang Y, Stein GS. Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains. Journal of Cell Science. 115: 4167-4176. PMID 12356919 DOI: 10.1242/Jcs.00095  0.371
2002 Lengner CJ, Drissi H, Choi JY, Wijnen AJV, Stein JL, Stein GS, Lian JB. Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton. Mechanisms of Development. 114: 167-170. PMID 12175505 DOI: 10.1016/S0925-4773(02)00050-3  0.444
2002 Pouliot A, Stein JL, Van Wijnen AJ, Stein GS, Lian JB. Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1 Journal of Cellular Biochemistry. 86: 403-412. PMID 12112009 DOI: 10.1002/Jcb.10238  0.462
2002 Zaidi SK, Sullivan AJ, Van Wijnen AJ, Stein JL, Stein GS, Lian JB. Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites Proceedings of the National Academy of Sciences of the United States of America. 99: 8048-8053. PMID 12060751 DOI: 10.1073/Pnas.112664499  0.385
2002 van der Meijden CM, Lapointe DS, Luong MX, Peric-Hupkes D, Cho B, Stein JL, van Wijnen AJ, Stein GS. Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly. Cancer Research. 62: 3233-43. PMID 12036939  0.323
2002 Paredes R, Gutiérrez J, Gutierrez S, Allison L, Puchi M, Imschenetzky M, Wijnen AV, Lian J, Stein G, Stein J, Montecino M. Interaction of the 1α, 25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodelling Biochemical Journal. 363: 667-676. PMID 11964167 DOI: 10.1042/0264-6021:3630667  0.389
2002 Drissi H, Pouliot A, Koolloos C, Stein JL, Lian JB, Stein GS, Wijnen AJv. 1,25-(OH)2-Vitamin D3 Suppresses the Bone-Related Runx2/Cbfa1 Gene Promoter Experimental Cell Research. 274: 323-333. PMID 11900492 DOI: 10.1006/Excr.2002.5474  0.467
2002 Shen J, Montecino M, Lian JB, Stein GS, Van Wijnen AJ, Stein JL. Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription Journal of Biological Chemistry. 277: 20284-20292. PMID 11893738 DOI: 10.1074/Jbc.M112440200  0.479
2002 Villagra A, Gutiérrez J, Paredes R, Sierra J, Puchi M, Imschenetzky M, Wijnen Av Av, Lian J, Stein G, Stein J, Montecino M. Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts. Journal of Cellular Biochemistry. 85: 112-22. PMID 11891855 DOI: 10.1002/Jcb.10113  0.466
2002 Luong MX, van der Meijden CM, Xing D, Hesselton R, Monuki ES, Jones SN, Lian JB, Stein JL, Stein GS, Neufeld EJ, van Wijnen AJ. Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility. Molecular and Cellular Biology. 22: 1424-37. PMID 11839809 DOI: 10.1128/Mcb.22.5.1424-1437.2002  0.411
2002 van den Bemd GJ, Jhamai M, Staal A, van Wijnen AJ, Lian JB, Stein GS, Pols HA, van Leeuwen JP. A central dinucleotide within vitamin D response elements modulates DNA binding and transactivation by the vitamin D receptor in cellular response to natural and synthetic ligands. The Journal of Biological Chemistry. 277: 14539-46. PMID 11834737 DOI: 10.1074/Jbc.M111224200  0.334
2002 Gilbert L, He X, Farmer P, Rubin J, Drissi H, van Wijnen AJ, Lian JB, Stein GS, Nanes MS. Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 277: 2695-701. PMID 11723115 DOI: 10.1074/Jbc.M106339200  0.399
2002 Gutierrez SE, Javed A, Tennant DK, Rees Mv, Montecino MA, Stein GS, Stein JL, Lian JB. CCAAT/Enhancer-binding Proteins (C/EBP) β and δ Activate Osteocalcin Gene Transcription and Synergize with Runx2 at the C/EBP Element to Regulate Bone-specific Expression Journal of Biological Chemistry. 277: 1316-1323. PMID 11668178 DOI: 10.1074/Jbc.M106611200  0.446
2002 Villagra A, Gutiérrez J, Paredes R, Sierra J, Puchi M, Imschenetzky M, Wijnen Av, Lian J, Stein G, Stein J, Montecino M. Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts*The contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. Journal of Cellular Biochemistry. 85: 112. DOI: 10.1002/Jcb.10113.Abs  0.372
2001 Mitra P, Vaughan PS, Stein JL, Stein GS, Wijnen AJv. Purification and Functional Analysis of a Novel Leucine-Zipper/Nucleotide-Fold Protein, BZAP45, Stimulating Cell Cycle Regulated Histone H4 Gene Transcription† Biochemistry. 40: 10693-10699. PMID 11524015 DOI: 10.1021/Bi010529O  0.465
2001 Banerjee C, Javed A, Choi JY, Green J, Rosen V, Wijnen AJV, Stein JL, Lian JB, Stein GS. Differential Regulation of the Two Principal Runx2/Cbfa1 N-Terminal Isoforms in Response to Bone Morphogenetic Protein-2 during Development of the Osteoblast Phenotype Endocrinology. 142: 4026-4039. PMID 11517182 DOI: 10.1210/Endo.142.9.8367  0.444
2001 Kim RD, Stein GS, Chari RS. Impact of cell swelling on proliferative signal transduction in the liver Journal of Cellular Biochemistry. 83: 56-69. PMID 11500954 DOI: 10.1002/Jcb.1205  0.338
2001 Choi JY, Pratap J, Javed A, Zaidi SK, Xing L, Balint E, Dalamangas S, Boyce B, Van Wijnen AJ, Lian JB, Stein JL, Jones SN, Stein GS. Subnuclear targeting of Runx/CBFa/AML factors is essential for tissue-specific differentiation during embryonic development Proceedings of the National Academy of Sciences of the United States of America. 98: 8650-8655. PMID 11438701 DOI: 10.1073/Pnas.151236498  0.42
2001 Chenoufi HL, Diamant M, Rieneck K, Lund B, Stein GS, Lian JB. Increased mRNA expression and protein secretion of interleukin-6 in primary human osteoblasts differentiated in vitro from rheumatoid and osteoarthritic bone Journal of Cellular Biochemistry. 81: 666-678. PMID 11329621 DOI: 10.1002/Jcb.1104  0.306
2001 Javed A, Barnes GL, Jasanya BO, Stein JL, Gerstenfeld L, Lian JB, Stein GS. Runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: Evidence for promoter context-dependent activity of Cbfa proteins Molecular and Cellular Biology. 21: 2891-2905. PMID 11283267 DOI: 10.1128/Mcb.21.8.2891-2905.2001  0.494
2001 Xie R, Wijnen AJV, Meijden CMJvd, Luong MX, Stein JL, Stein GS. The Cell Cycle Control Element of Histone H4 Gene Transcription Is Maximally Responsive to Interferon Regulatory Factor Pairs IRF-1/IRF-3 and IRF-1/IRF-7 Journal of Biological Chemistry. 276: 18624-18632. PMID 11278666 DOI: 10.1074/Jbc.M010391200  0.473
2001 Shopland LS, Byron M, Stein JL, Lian JB, Stein GS, Lawrence JB. Replication-dependent histone gene expression is related to Cajal body (CB) association but does not require sustained CB contact. Molecular Biology of the Cell. 12: 565-76. PMID 11251071 DOI: 10.1091/Mbc.12.3.565  0.472
2001 Lian JB, Stein JL, Stein GS, Montecino M, Wijnen AJV, Javed A, Gutierrez SE. Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene. Steroids. 66: 159-170. PMID 11179723 DOI: 10.1016/S0039-128X(00)00160-4  0.429
2001 Prince M, Banerjee C, Javed A, Green J, Lian JB, Stein GS, Bodine PVN, Komm BS. Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts Journal of Cellular Biochemistry. 80: 424-440. PMID 11135373 DOI: 10.1002/1097-4644(20010301)80:3<424::Aid-Jcb160>3.0.Co;2-6  0.443
2001 Leboy PS, Grasso-Knight G, D'Angelo M, Volk SW, Lian JV, Drissi H, Stein GS, Adams SL. Smad-Runx interactions during chondrocyte maturation. Journal of Bone and Joint Surgery, American Volume. 83. DOI: 10.2106/00004623-200100001-00003  0.447
2001 Lian JB, Stein GS, Stein JL. Stem cell and gene therapy approaches for skeletal disorders Current Opinion in Endocrinology and Diabetes. 8: 268-276. DOI: 10.1097/00060793-200112000-00002  0.31
2000 Brown RS, Shalhoub V, Coulter S, Alex S, Joris I, De Vito W, Lian J, Stein GS. Developmental Regulation of Thyrotropin Receptor Gene Expression in the Fetal and Neonatal Rat Thyroid: Relation to Thyroid Morphology and to Thyroid-Specific Gene Expression1. Endocrinology. 141: 340-345. PMID 28200989 DOI: 10.1210/Endo.141.1.7258  0.323
2000 Stein GS, Wijnen AJV, Stein JL, Lian JB, Montecino MA, Zaidi K, Javed A. Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer. Journal of Cellular Biochemistry. 79: 84-92. PMID 11389536 DOI: 10.1002/1097-4644(2000)79:35+<84::Aid-Jcb1130>3.0.Co;2-9  0.375
2000 Gutiérrez J, Sierra J, Medina R, Puchi M, Imschenetzky M, van Wijnen A, Lian J, Stein G, Stein J, Montecino M. Interaction of CBF alpha/AML/PEBP2 alpha transcription factors with nucleosomes containing promoter sequences requires flexibility in the translational positioning of the histone octamer and exposure of the CBF alpha site. Biochemistry. 39: 13565-74. PMID 11063594 DOI: 10.1021/Bi0013896  0.384
2000 Lian JB, Stein GS, Steins JL, Van Wijnen AJ. Marrow transplantation and targeted gene therapy to the skeleton Clinical Orthopaedics and Related Research. PMID 11039763 DOI: 10.1097/00003086-200010001-00019  0.445
2000 Hoffmann H, Green J, Van Wijnen AJ, Stein JL, Stein GS, Lian JB. Expression screening of factors binding to the osteocalcin bone-specific promoter element OC box I: Isolation of a novel osteoblast differentiation-specific factor Journal of Cellular Biochemistry. 80: 156-168. PMID 11029763 DOI: 10.1002/1097-4644(20010101)80:1<156::Aid-Jcb150>3.0.Co;2-F  0.458
2000 Staal A, Enserink JM, Stein JL, Stein GS, van Wijnen AJ. Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2. Journal of Cellular Physiology. 185: 269-79. PMID 11025449 DOI: 10.1002/1097-4652(200011)185:2<269::Aid-Jcp12>3.0.Co;2-L  0.462
2000 Drissi H, Luc Q, Shakoori AR, Lopes SCDS, Choi J, Terry A, Hu M, Jones SN, Neil JC, Lian JB, Stein JL, Wijnen AJV, Stein GS. Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene Journal of Cellular Physiology. 184: 341-350. PMID 10911365 DOI: 10.1002/1097-4652(200009)184:3<341::Aid-Jcp8>3.0.Co;2-Z  0.494
2000 McNeil SM, Javed A, Harrington KS, Lian JB, Stein JL, Wijnen AJV, Stein GS. Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies. Journal of Cellular Biochemistry. 79: 103-112. PMID 10906759 DOI: 10.1002/1097-4644(2000)79:1<103::Aid-Jcb100>3.0.Co;2-B  0.411
2000 Stein GS, Lian JB, Stein JL, Van Wijnen AJ. Bone tissue specific transcriptional control: Options for targeting gene therapy to the skeleton Cancer. 88: 2899-2902. PMID 10898331 DOI: 10.1002/1097-0142(20000615)88:12+<2899::Aid-Cncr3>3.0.Co;2-O  0.461
2000 Gordon JA, Pockwinse SM, Stewart FM, Quesenberry PJ, Nakamura T, Croce CM, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Modified intranuclear organization of regulatory factors in human acute leukemias: reversal after treatment. Journal of Cellular Biochemistry. 77: 30-43. PMID 10679814 DOI: 10.1002/(Sici)1097-4644(20000401)77:1<30::Aid-Jcb4>3.0.Co;2-K  0.434
2000 McNeil S, Zeng C, Harrington KS, Hiebert S, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 96: 14882-7. PMID 10611307 DOI: 10.1073/Pnas.96.26.14882  0.385
2000 Chaum E, Hatton MP, Stein G. Polyplex-mediated gene transfer into human retinal pigment epithelial cells in vitro. Journal of Cellular Biochemistry. 76: 153-160. PMID 10581009 DOI: 10.1002/(Sici)1097-4644(20000101)76:1<153::Aid-Jcb15>3.0.Co;2-#  0.393
2000 Stein G, Berezney R. NUCLEAR STRUCTURE AND GENE EXPRESSION(Part Two of a Two-Part Series) Edited by Gary S.Stein and Ronald Berezney25 Years of Contributions to Characterizing Gene Expression and Replication within the Three-Dimensional Context of Nuclear Architecture Critical Reviews™ in Eukaryotic Gene Expression. 10: 2. DOI: 10.1615/Critreveukargeneexpr.V10.I1.10  0.383
1999 Stein GS, Van Wijnen AJ, Stein JL, Lian JB. Interrelationships of transcriptional machinery with nuclear architecture Critical Reviews in Eukaryotic Gene Expression. 9: 183-190. PMID 10651235 DOI: 10.1615/Critreveukargeneexpr.V9.I3-4.30  0.439
1999 Stein GS, Wijnen AJV, Stein JL, Lian JB, McNeil SM, Pockwinse SM. Transcriptional control within the three-dimensional context of nuclear architecture: requirements for boundaries and direction. Journal of Cellular Biochemistry. 75: 24-31. PMID 10629100 DOI: 10.1002/(Sici)1097-4644(1999)75:32+<24::Aid-Jcb4>3.0.Co;2-V  0.47
1999 Stein GS, Wijnen AJV, Stein JL, Lian JB, Javed A, McNeil SM, Pockwinse SM. Insight into regulatory factor targeting to transcriptionally active subnuclear sites. Experimental Cell Research. 253: 110-116. PMID 10579916 DOI: 10.1006/Excr.1999.4680  0.409
1999 Tang L, Guo B, Javed A, Choi JY, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Zhou GW. Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2. The Journal of Biological Chemistry. 274: 33580-6. PMID 10559245 DOI: 10.1074/Jbc.274.47.33580  0.375
1999 Wijnen AJv, Ridder MCd, Stein GS, Stein JL. The homeodomain transcription factor CDP/cut interacts with the cell cycle regulatory element of histone H4 genes packaged into nucleosomes. Molecular Biology Reports. 26: 185-194. PMID 10532314 DOI: 10.1023/A:1007058123699  0.44
1999 Javed A, Gutierrez SE, Montecino M, Wijnen AJV, Stein JL, Stein GS, Lian JB. Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization Molecular and Cellular Biology. 19: 7491-7500. PMID 10523637 DOI: 10.1128/Mcb.19.11.7491  0.405
1999 Quesenberry PJ, Hulspas R, Joly M, Benoit B, Engstrom C, Rielly J, Savarese T, Pang L, Recht L, Ross A, Stein G, Stewart M. Correlates between hematopoiesis and neuropoiesis: neural stem cells. Journal of Neurotrauma. 16: 661-6. PMID 10511238 DOI: 10.1089/Neu.1999.16.661  0.314
1999 Stein GS, Van Wijnen AJ, Montecino M, Stein JL, Lian JB. Nuclear structure/gene expression interrelationships Journal of Cellular Physiology. 181: 240-250. PMID 10497303 DOI: 10.1002/(Sici)1097-4652(199911)181:2<240::Aid-Jcp6>3.0.Co;2-K  0.366
1999 Hou Z, Nguyen Q, Frenkel B, Nilsson SK, Milne M, Van Wijnen AJ, Stein JL, Quesenberry P, Lian JB, Stein GS. Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy Proceedings of the National Academy of Sciences of the United States of America. 96: 7294-7299. PMID 10377408 DOI: 10.1073/Pnas.96.13.7294  0.442
1999 Stein GS, Wijnen AJV, Stein JL, Lian JB, Pockwinse SM, McNeil SM. Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions The Faseb Journal. 13: 157-166. PMID 10352158 DOI: 10.1096/Fasebj.13.9001.S157  0.457
1999 Lee MH, Javed A, Kim HJ, Shin HI, Gutierrez S, Choi JY, Rosen V, Stein JL, Wijnen AJV, Stein GS, Lian JB, Ryoo HM. Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation. Journal of Cellular Biochemistry. 73: 114-125. PMID 10088730 DOI: 10.1002/(Sici)1097-4644(19990401)73:1<114::Aid-Jcb13>3.0.Co;2-M  0.459
1999 Montecino M, Van Wijnen AJ, Lian JB, Stein JL, Stein GS. Phosphorylation-mediated control of chromatin organization and transcriptional activity of the tissue-specific osteocalcin gene Journal of Cellular Biochemistry. 72: 586-594. PMID 10022617 DOI: 10.1002/(Sici)1097-4644(19990315)72:4<586::Aid-Jcb13>3.0.Co;2-K  0.492
1999 Last TJ, Van Wijnen AJ, Birnbaum MJ, Stein GS, Stein JL. Multiple interactions of the transcription factor YY1 with human histone H4 gene regulatory elements Journal of Cellular Biochemistry. 72: 507-516. PMID 10022610 DOI: 10.1002/(Sici)1097-4644(19990315)72:4<507::Aid-Jcb6>3.0.Co;2-5  0.457
1999 Nilsson SK, Dooner MS, Weier HU, Frenkel B, Lian JB, Stein GS, Quesenberry PJ. Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice Journal of Experimental Medicine. 189: 729-734. PMID 9989988 DOI: 10.1084/Jem.189.4.729  0.336
1999 Montecino M, Frenkel B, Van Wijnen AJ, Lian JB, Stein GS, Stein JL. Chromatin hyperacetylation abrogates vitamin D-mediated transcriptional upregulation of the tissue-specific osteocalcin gene in vivo Biochemistry. 38: 1338-1345. PMID 9930996 DOI: 10.1021/Bi982171A  0.469
1999 Aslam F, McCabe L, Frenkel B, Van Wijnen AJ, Stein GS, Lian JB, Stein JL. AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: Requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation Endocrinology. 140: 63-70. PMID 9886808 DOI: 10.1210/Endo.140.1.6429  0.362
1999 Stein G, Berezney R. NUCLEAR STRUCTURE AND GENE EXPRESSION (Part One of a Two-Part Series) Critical Reviews™ in Eukaryotic Gene Expression. 9: v-vi. DOI: 10.1615/Critreveukargeneexpr.V9.I3-4.10  0.363
1998 Lian JB, Stein GS, Stein JL, Wijnen AJv. Osteocalcin gene promoter: Unlocking the secrets for regulation of osteoblast growth and differentiation. Journal of Cellular Biochemistry. 72: 62-72. PMID 29345833 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<62::Aid-Jcb10>3.0.Co;2-S  0.489
1998 Stein GS, Wijnen AJV, Stein JL, Lian JB, Pockwinse SM, McNeil SM. Linkages of nuclear architecture to biological and pathological control of gene expression. Journal of Cellular Biochemistry. 72: 220-231. PMID 29345822 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<220::Aid-Jcb27>3.0.Co;2-W  0.479
1998 Carulli JP, Artinger M, Swain PM, Root CD, Chee L, Tulig C, Guerin J, Osborne M, Stein G, Lian J, Lomedico PT. High throughput analysis of differential gene expression. Journal of Cellular Biochemistry. 72: 286-296. PMID 29345813 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<286::Aid-Jcb35>3.0.Co;2-D  0.408
1998 Bodine PV, Henderson RA, Green J, Aronow M, Owen T, Stein GS, Lian JB, Komm BS. Estrogen Receptor-α Is Developmentally Regulated during Osteoblast Differentiation and Contributes to Selective Responsiveness of Gene Expression. Endocrinology. 139: 2048-2057. PMID 28200396 DOI: 10.1210/Endo.139.4.5897  0.404
1998 Lian JB, Stein GS, Stein JL, Van Wijnen AJ. Transcriptional control of osteoblast differentiation Biochemical Society Transactions. 26: 14-21. PMID 10909750 DOI: 10.1042/Bst0260014  0.371
1998 Lian JB, Stein GS, Stein JL, Van Wijnen AJ. Regulated Expression of the Bone-Specific Osteocalcin Gene by Vitamins and Hormones Vitamins and Hormones. 55: 443-509. PMID 9949687 DOI: 10.1016/S0083-6729(08)60941-3  0.399
1998 Birnbaum MJ, Wijnen AJV, Stein GS, Stein JL. Repressor elements in the coding region of the human histone H4 gene interact with the transcription factor CDP/cut Gene. 221: 267-277. PMID 9874597 DOI: 10.1016/S0378-1119(98)00415-6  0.456
1998 Aziz F, Van Wijnen AJ, Stein JL, Stein GS. HiNF-D (CDP-cut/CDC2/cyclin A/pRB-complex) influences the timing of IRF- 2-dependent cell cycle activation of human histone H4 gene transcription at the G1/S phase transition Journal of Cellular Physiology. 177: 453-464. PMID 9808153 DOI: 10.1002/(Sici)1097-4652(199812)177:3<453::Aid-Jcp8>3.0.Co;2-F  0.455
1998 van der Meijden CM, Vaughan PS, Staal A, Albig W, Doenecke D, Stein JL, Stein GS, van Wijnen AJ. Selective expression of specific histone H4 genes reflects distinctions in transcription factor interactions with divergent H4 promoter elements. Biochimica Et Biophysica Acta. 1442: 82-100. PMID 9767124 DOI: 10.1016/S0167-4781(98)00147-X  0.452
1998 Stein GS, van Wijnen AJ, Stein JL, Lian JB. Nuclear structure--skeletal gene expression interrelationships Frontiers in Bioscience : a Journal and Virtual Library. 3. PMID 9682039 DOI: 10.2741/A328  0.475
1998 Stein GS, Wijnen AJV, Stein JL, Lian JB, Pockwinse SM, McNeil SM. Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time. Journal of Cellular Biochemistry. 70: 200-212. PMID 9671226 DOI: 10.1002/(Sici)1097-4644(19980801)70:2<200::Aid-Jcb6>3.0.Co;2-S  0.457
1998 Ji C, Casinghino S, Chang DJ, Chen Y, Javed A, Ito Y, Hiebert SW, Lian JB, Stein GS, McCarthy TL, Centrella M. CBFa(AML/PEBP2)-related elements in the TGF-β type I receptor promoter and expression with osteoblast differentiation Journal of Cellular Biochemistry. 69: 353-363. PMID 9581873 DOI: 10.1002/(Sici)1097-4644(19980601)69:3<353::Aid-Jcb12>3.0.Co;2-D  0.408
1998 Lindenmuth D, van Wijnen AJ, Penman S, Stein JL, Stein GS, Lian JB. TGF-beta1 modifications in nuclear matrix proteins of osteoblasts during differentiation. Journal of Cellular Biochemistry. 69: 291-303. PMID 9581868 DOI: 10.1002/(Sici)1097-4644(19980601)69:3<291::Aid-Jcb7>3.0.Co;2-M  0.306
1998 Shalhoub V, Aslam F, Breen EC, Wijnen AJV, Bortell R, Stein GS, Stein JL, Lian JB. Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: glucocorticoid regulation of basal and vitamin D stimulated gene expression Journal of Cellular Biochemistry. 69: 154-168. PMID 9548563 DOI: 10.1002/(Sici)1097-4644(19980501)69:2<154::Aid-Jcb6>3.0.Co;2-R  0.463
1998 Bagchi M, Ansari SA, Lindenmuth DM, Wijnen AJV, Lian JB, Stein JL, Stein GS. Nuclear matrix associated DNA-binding proteins of ocular lens epithelial cells Molecular Biology Reports. 25: 13-19. PMID 9540063 DOI: 10.1023/A:1006886110771  0.436
1998 Aziz F, van Wijnen AJ, Vaughan PS, Wu S, Shakoori AR, Lian JB, Soprano KJ, Stein JL, Stein GS. The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes. Molecular Biology Reports. 25: 1-12. PMID 9540062 DOI: 10.1023/A:1006888731301  0.446
1998 McNeil S, Guo B, Stein JL, Lian JB, Bushmeyer S, Seto E, Atchison ML, Penman S, van Wijnen AJ, Stein GS. Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking. Journal of Cellular Biochemistry. 68: 500-10. PMID 9493912 DOI: 10.1002/(Sici)1097-4644(19980315)68:4<500::Aid-Jcb9>3.0.Co;2-U  0.397
1998 Zeng C, McNeil S, Pockwinse S, Nickerson J, Shopland L, Lawrence JB, Penman S, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains. Proceedings of the National Academy of Sciences of the United States of America. 95: 1585-9. PMID 9465059 DOI: 10.1073/Pnas.95.4.1585  0.399
1998 Vaughan PS, Meijden CMJvd, Aziz F, Harada H, Taniguchi T, Wijnen AJv, Stein JL, Stein GS. Cell Cycle Regulation of Histone H4 Gene Transcription Requires the Oncogenic Factor IRF-2 Journal of Biological Chemistry. 273: 194-199. PMID 9417064 DOI: 10.1074/Jbc.273.1.194  0.498
1998 Lynch MP, Capparelli C, Stein JL, Stein GS, Lian JB. Apoptosis during bone-like tissue development in vitro. Journal of Cellular Biochemistry. 68: 31-49. PMID 9407312 DOI: 10.1002/(Sici)1097-4644(19980101)68:1<31::Aid-Jcb4>3.0.Co;2-X  0.408
1998 Stein GS. Interrelationships of nuclear architecture with gene expression: Functional encounters on a long and winding road Journal of Cellular Biochemistry. 70: 157-158. DOI: 10.1002/(Sici)1097-4644(19980801)70:2<157::Aid-Jcb1>3.0.Co;2-N  0.312
1997 Guo B, Stein JL, Van Wijnen AJ, Stein GS. ATF1 and CREB trans-activate a cell cycle regulated histone H4 gene at a distal nuclear matrix associated promoter element Biochemistry. 36: 14447-14455. PMID 9398163 DOI: 10.1021/Bi971781S  0.482
1997 Ryoo HM, Hoffmann HM, Beumer T, Frenkel B, Towler DA, Stein GS, Stein JL, van Wijnen AJ, Lian JB. Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression. Molecular Endocrinology (Baltimore, Md.). 11: 1681-94. PMID 9328350 DOI: 10.1210/Mend.11.11.0011  0.481
1997 Stein GS, Lian JB, Van Wijnen AJ, Stein JL. The osteocalcin gene: A model for multiple parameters of skeletal-specific transcriptional control Molecular Biology Reports. 24: 185-196. PMID 9291092 DOI: 10.1023/A:1006803615430  0.474
1997 Wijnen AJV, Cooper CL, Odgren PR, Aziz F, Luca AD, Shakoori AR, Giordano A, Quesenberry PJ, Lian JB, Stein GS, Stein JL. Cell cycle-dependent modifications in activities of pRb-related tumor suppressors and proliferation-specific CDP/cut homeodomain factors in murine hematopoietic progenitor cells Journal of Cellular Biochemistry. 66: 512-523. PMID 9282329 DOI: 10.1002/(Sici)1097-4644(19970915)66:4<512::Aid-Jcb10>3.0.Co;2-D  0.45
1997 Lucas TS, Bab IA, Lian JB, Stein GS, Jazrawi L, Majeska RJ, Attar-Namdar M, Einhorn TA. Stimulation of systemic bone formation induced by experimental blood loss. Clinical Orthopaedics and Related Research. 267-75. PMID 9224265 DOI: 10.1097/00003086-199707000-00034  0.315
1997 Lindenmuth DM, van Wijnen AJ, Hiebert S, Stein JL, Lian JB, Stein GS. Subcellular partitioning of transcription factors during osteoblast differentiation: developmental association of the AML/CBF alpha/PEBP2 alpha-related transcription factor-NMP-2 with the nuclear matrix. Journal of Cellular Biochemistry. 66: 123-32. PMID 9215534 DOI: 10.1002/(Sici)1097-4644(19970701)66:1<123::Aid-Jcb13>3.0.Co;2-K  0.463
1997 Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB. Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex Journal of Cellular Biochemistry. 66: 1-8. PMID 9215522 DOI: 10.1002/(Sici)1097-4644(19970701)66:1<1::Aid-Jcb1>3.0.Co;2-V  0.468
1997 Birnbaum MJ, Van Zundert B, Vaughan PS, Whitmarsh AJ, Van Wijnen AJ, Davis RJ, Stein GS, Stein JL. Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo Journal of Cellular Biochemistry. 66: 175-183. PMID 9213219 DOI: 10.1002/(Sici)1097-4644(19970801)66:2<175::Aid-Jcb5>3.0.Co;2-N  0.342
1997 Smith E, Frenkel B, MacLachlan TK, Giordano A, Stein JL, Lian JB, Stein GS. Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: Inhibition by proliferating osteoblasts and osteosarcoma cells Journal of Cellular Biochemistry. 66: 141-152. PMID 9213216 DOI: 10.1002/(Sici)1097-4644(19970801)66:2<141::Aid-Jcb2>3.0.Co;2-Q  0.331
1997 Zeng C, van Wijnen AJ, Stein JL, Meyers S, Sun W, Shopland L, Lawrence JB, Penman S, Lian JB, Stein GS, Hiebert SW. Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 94: 6746-51. PMID 9192636 DOI: 10.1073/Pnas.94.13.6746  0.415
1997 Vaughan PS, Van Wijnen AJ, Stein JL, Stein GS. Interferon regulatory factors: Growth control and histone gene regulation - It's not just interferon anymore Journal of Molecular Medicine. 75: 348-359. PMID 9181476 DOI: 10.1007/S001090050120  0.427
1997 Bodine PVN, Green J, Harris HA, Bhat RA, Stein GS, Lian JB, Komm BS. Functional properties of a conditionally phenotypic, estrogen- responsive, human osteoblast cell line Journal of Cellular Biochemistry. 65: 368-387. PMID 9138093 DOI: 10.1002/(Sici)1097-4644(19970601)65:3<368::Aid-Jcb7>3.0.Co;2-Q  0.369
1997 Lian JB, Shalhoub V, Aslam F, Frenkel B, Green J, Hamrah M, Stein GS, Stein JL. Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: Dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression Endocrinology. 138: 2117-2127. PMID 9112412 DOI: 10.1210/Endo.138.5.5117  0.426
1997 Frenkel B, Capparelli C, Van Auken M, Baran D, Bryan J, Stein JL, Stein GS, Lian JB. Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: Effects of age and sex Endocrinology. 138: 2109-2116. PMID 9112411 DOI: 10.1210/Endo.138.5.5105  0.397
1997 Pockwinse SM, Krockmalnic G, Doxsey SJ, Nickerson J, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Penman S. Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold. Proceedings of the National Academy of Sciences of the United States of America. 94: 3022-7. PMID 9096339 DOI: 10.1073/Pnas.94.7.3022  0.324
1997 Ryoo HM, Van Wijnen AJ, Stein JL, Lian JB, Stein GS. Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display Journal of Cellular Biochemistry. 64: 106-116. PMID 9015759 DOI: 10.1002/(Sici)1097-4644(199701)64:1<106::Aid-Jcb13>3.0.Co;2-J  0.468
1997 Guo B, Aslam F, Van Wijnen AJ, Roberts SGE, Frenkel B, Green MR, Deluca H, Lian JB, Stein GS, Stein JL. YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene Proceedings of the National Academy of Sciences of the United States of America. 94: 121-126. PMID 8990171 DOI: 10.1073/Pnas.94.1.121  0.386
1996 Hoffmann HM, Beumer TL, Rahman S, McCabe LR, Banerjee C, Aslam F, Tiro JA, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Bone tissue-specific transcription of the osteocalcin gene: role of an activator osteoblast-specific complex and suppressor hox proteins that bind the OC box. Journal of Cellular Biochemistry. 61: 310-24. PMID 9173094 DOI: 10.1002/(Sici)1097-4644(19960501)61:2<310::Aid-Jcb14>3.0.Co;2-P  0.464
1996 Lian JB, Stein GS, Stein JL, Wijnen AJV, McCabe LR, Banerjee C, Hoffmann HM. The Osteocalcin Gene Promoter Provides a Molecular Blueprint for Regulatory Mechanisms Controlling Bone Tissue Formation: Role of Transcription Factors Involved in Development Connective Tissue Research. 35: 15-21. PMID 9084639 DOI: 10.3109/03008209609029170  0.436
1996 Stein GS, Stein JL, Van Wijnen AJ, Lian JB. Transcriptional control of cell cycle progression: The histone gene is a paradigm for the G1/S phase and proliferation/differentiation transitions Cell Biology International. 20: 41-49. PMID 8936406 DOI: 10.1006/Cbir.1996.0007  0.492
1996 Staal A, van Wijnen AJ, Birkenhäger JC, Pols HA, Prahl J, DeLuca H, Gaub MP, Lian JB, Stein GS, van Leeuwen JP, Stein JL. Distinct conformations of vitamin D receptor/retinoid X receptor-alpha heterodimers are specified by dinucleotide differences in the vitamin D-responsive elements of the osteocalcin and osteopontin genes. Molecular Endocrinology (Baltimore, Md.). 10: 1444-56. PMID 8923469 DOI: 10.1210/Mend.10.11.8923469  0.342
1996 Montecino M, Frenkel B, Lian J, Stein J, Stein G. Requirement of distal and proximal promoter sequences for chromatin organization of the osteocalcin gene in bone-derived cells Journal of Cellular Biochemistry. 63: 221-228. PMID 8913873 DOI: 10.1002/(SICI)1097-4644(19961101)63:2<221::AID-JCB9>3.0.CO;2-#  0.478
1996 Wijnen AJv, Gurp MFv, Ridder MCd, Tufarelli C, Birnbaum M, Vaughan PS, Giordano A, Krek W, Neufeld EJ, Stein JL, Stein GS. CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F. Proceedings of the National Academy of Sciences of the United States of America. 93: 11516-11521. PMID 8876167 DOI: 10.1073/Pnas.93.21.11516  0.455
1996 Stein GS, Stein JL, Lian JB, Wijnen AJV, Montecino MA. Functional interrelationships between nuclear structure and transcriptional control: contributions to regulation of cell cycle- and tissue-specific gene expression. Journal of Cellular Biochemistry. 62: 198-209. PMID 8844400 DOI: 10.1002/(Sici)1097-4644(199608)62:2<198::Aid-Jcb8>3.0.Co;2-N  0.46
1996 McCabe LR, Banerjee C, Kundu R, Harrison RJ, Dobner PR, Stein JL, Lian JB, Stein GS. Developmental expression and activities of specific fos and jun proteins are functionally related to osteoblast maturation: role of Fra-2 and Jun D during differentiation. Endocrinology. 137: 4398-408. PMID 8828501 DOI: 10.1210/Endo.137.10.8828501  0.438
1996 Quesenberry PJ, Iscove NN, Cooper CL, Brady G, Newburger PE, Stein GS, Stein JL, Reddy GPV, Pearson-White S. Expression of basic helix-loop-helix transcription factors in explant hematopoietic progenitors. Journal of Cellular Biochemistry. 61: 478-488. PMID 8761952 DOI: 10.1002/(Sici)1097-4644(19960601)61:3<478::Aid-Jcb15>3.0.Co;2-F  0.381
1996 Tang KT, Capparelli C, Stein JL, Stein GS, Lian JB, Huber AC, Braverman LE, DeVito WJ. Acidic fibroblast growth factor inhibits osteoblast differentiation in vitro: altered expression of collagenase, cell growth-related, and mineralization-associated genes. Journal of Cellular Biochemistry. 61: 152-66. PMID 8726364 DOI: 10.1002/(Sici)1097-4644(19960401)61:1<152::Aid-Jcb16>3.0.Co;2-Q  0.393
1996 Montecino M, Lian J, Stein G, Stein J. Changes in chromatin structure support constitutive and developmentally regulated transcription of the bone-specific osteocalcin gene in osteoblastic cells. Biochemistry. 35: 5093-5102. PMID 8664302 DOI: 10.1021/Bi952489S  0.511
1996 Banerjee C, Hiebert SW, Stein JL, Lian JB, Stein GS. An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene Proceedings of the National Academy of Sciences of the United States of America. 93: 4968-4973. PMID 8643513 DOI: 10.1073/Pnas.93.10.4968  0.469
1996 Stein GS, Lian JB, Stein JL, Van Wijnen AJ, Montecino M. Transcriptional control of osteoblast growth and differentiation Physiological Reviews. 76: 593-629. PMID 8618964 DOI: 10.1152/Physrev.1996.76.2.593  0.494
1996 Staal A, Van Wijnen AJ, Desai RK, Pols HA, Birkenhäger JC, Deluca HF, Denhardt DT, Stein JL, Van Leeuwen JP, Stein GS, Lian JB. Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements. Endocrinology. 137: 2001-11. PMID 8612541 DOI: 10.1210/Endo.137.5.8612541  0.344
1996 Banerjee C, Stein JL, Van Wijnen AJ, Frenkel B, Lian JB, Stein GS. Transforming growth factor-β1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site Endocrinology. 137: 1991-2000. PMID 8612540 DOI: 10.1210/Endo.137.5.8612540  0.353
1996 Frenkel B, Montecino M, Green J, Aslam F, Desai R, Banerjee C, Stein JL, Lian JB, Stein GS. Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: Requirement of upstream sequences for control by the proximal regulatory domain Endocrinology. 137: 1080-1088. PMID 8603577 DOI: 10.1210/Endo.137.3.8603577  0.469
1996 Shalhoub V, Jackson ME, Paradise C, Stein GS, Lian JB, Marks SC. Heterogeneity of colony stimulating factor-1 gene expression in the skeleton of four osteopetrotic mutations in rats and mice. Journal of Cellular Physiology. 166: 340-50. PMID 8591994 DOI: 10.1002/(Sici)1097-4652(199602)166:2<340::Aid-Jcp12>3.0.Co;2-F  0.37
1995 Birnbaum MJ, Van Wijnen AJ, Odgren PR, Last TJ, Suske G, Stein GS, Stein JL. Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3 Biochemistry. 34: 16503-16508. PMID 8845379 DOI: 10.1021/Bi00050A034  0.365
1995 Aslam F, Shalhoub V, van Wijnen AJ, Banerjee C, Bortell R, Shakoori AR, Litwack G, Stein JL, Stein GS, Lian JB. Contributions of distal and proximal promoter elements to glucocorticoid regulation of osteocalcin gene transcription. Molecular Endocrinology (Baltimore, Md.). 9: 679-90. PMID 8592514 DOI: 10.1210/Mend.9.6.8592514  0.393
1995 Stein GS, Van Wijnen AJ, Stein J, Lian JB, Montecino M. Contributions of nuclear architecture to transcriptional control International Review of Cytology. 162: 251-278. PMID 8575882 DOI: 10.1016/S0074-7696(08)61233-4  0.497
1995 Shakoori AR, Van Wijnen AJ, Cooper C, Aziz F, Birnbaum M, Reddy GPV, Grana X, De Luca A, Giordano A, Lian JB, Stein JL, Quesenberry P, Stein GS. Cytokine induction of proliferation and expression of CDC2 and cyclin A in FDC-P1 myeloid hematopoietic progenitor cells: Regulation of ubiquitous and cell cycle-dependent histone gene transcription factors Journal of Cellular Biochemistry. 59: 291-302. PMID 8567748 DOI: 10.1002/Jcb.240590302  0.515
1995 Lynch MP, Stein JL, Stein GS, Lian JB. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization. Experimental Cell Research. 216: 35-45. PMID 7813631 DOI: 10.1006/Excr.1995.1005  0.431
1995 Pockwinse SM, Stein JL, Lian JB, Stein GS. Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: Interrelationship of morphology and gene expression by in situ hybridization Experimental Cell Research. 216: 244-260. PMID 7813627 DOI: 10.1006/Excr.1995.1031  0.46
1995 Menconi MJ, Pockwinse SM, Owen TA, Dasse KA, Stein GS, Lian JB. Properties of blood-contacting surfaces of clinically implanted cardiac assist devices: Gene expression, matrix composition, and ultrastructural characterization of cellular linings Journal of Cellular Biochemistry. 57: 557-573. PMID 7768989 DOI: 10.1002/Jcb.240570320  0.303
1995 Kroeger PE, Van Wijnen AJ, Pauli U, Wright KL, Stein GS, Stein JL. In vivo occupancy of histone gene proximal promoter elements reflects gene copy number-dependent titratable transactivation factors and cross-species compatibility of regulatory sequences Journal of Cellular Biochemistry. 57: 191-207. PMID 7759557 DOI: 10.1002/Jcb.240570204  0.451
1995 McCabe LR, Kockx M, Lian J, Stein J, Stein G. Selective expression of fos- and jun-related genes during osteoblast proliferation and differentiation. Experimental Cell Research. 218: 255-262. PMID 7737363 DOI: 10.1006/Excr.1995.1154  0.411
1995 Heinrichs AAJ, Bortell R, Bourke M, Lian JB, Stein GS, Stein JL. Proximal promoter binding protein contributes to developmental, tissue-restricted expression of the rat osteocalcin gene. Journal of Cellular Biochemistry. 57: 90-100. PMID 7721961 DOI: 10.1002/Jcb.240570110  0.452
1995 Ramsey-Ewing AL, Bortell R, Stein GS, Stein JL. Histone H4 proximal promoter mediates a complex transcriptional response during differentiation of 3T3L1 adipocytes Journal of Cellular Physiology. 163: 312-320. PMID 7706376 DOI: 10.1002/Jcp.1041630212  0.484
1995 Wright KL, Birnbaum MJ, van Wijnen AJ, Stein GS, Stein JL. Bipartite structure of the proximal promoter of a human H4 histone gene. Journal of Cellular Biochemistry. 58: 372-9. PMID 7593258 DOI: 10.1002/Jcb.240580310  0.379
1995 Desai RK, Van Wijnen AJ, Stein JL, Stein GS, Lian JB. Control of 1,25-dihydroxyvitamin D3 receptor-mediated enhancement of osteocalcin gene transcription: Effects of perturbing phosphorylation pathways by okadaic acid and staurosporine Endocrinology. 136: 5685-5693. PMID 7588324 DOI: 10.1210/Endo.136.12.7588324  0.403
1995 Vaughan PS, Aziz F, van Wijnen AJ, Wu S, Harada H, Taniguchi T, Soprano KJ, Stein JL, Stein GS. Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2. Nature. 377: 362-5. PMID 7566094 DOI: 10.1038/377362A0  0.469
1995 Merriman HL, Van Wijnen AJ, Hiebert S, Bidwell JP, Fey E, Lian J, Stein J, Stein GS. The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: Interactions with the osteocalcin gene promoter Biochemistry. 34: 13125-13132. PMID 7548073 DOI: 10.1021/Bi00040A025  0.409
1995 Guo B, Odgren PR, van Wijnen AJ, Last TJ, Nickerson J, Penman S, Lian JB, Stein JL, Stein GS. The nuclear matrix protein NMP-1 is the transcription factor YY1. Proceedings of the National Academy of Sciences of the United States of America. 92: 10526-30. PMID 7479833 DOI: 10.1073/Pnas.92.23.10526  0.436
1994 Montecino M, Pockwinse S, Lian J, Stein G, Stein J. DNase I hypersensitive sites in promoter elements associated with basal and vitamin D dependent transcription of the bone-specific osteocalcin gene Biochemistry. 33: 348-353. PMID 8286356 DOI: 10.1021/Bi00167A045  0.475
1994 Shalhoub V, Bettencourt B, Jackson ME, MacKay CA, Glimcher MJ, Marks SC, Stein GS, Lian JB. Abnormalities of phosphoprotein gene expression in three osteopetrotic rat mutations: elevated mRNA transcripts, protein synthesis, and accumulation in bone of mutant animals. Journal of Cellular Physiology. 158: 110-20. PMID 8263018 DOI: 10.1002/Jcp.1041580114  0.363
1994 Rahman S, Oberdorf A, Montecino M, Tanhauser SM, Lian JB, Stein GS, Laipis PJ, Stein JL. Multiple copies of the bone-specific osteocalcin gene in mouse and rat. Endocrinology. 133: 3050-3. PMID 8243336 DOI: 10.1210/Endo.133.6.8243336  0.396
1994 Bollerslev J, Marks SC, Mosekilde L, Lian JB, Stein GS. Cortical bone osteocalcin content and matrix composition in autosomal dominant osteopetrosis type I European Journal of Endocrinology. 130: 592-594. PMID 8205260 DOI: 10.1530/Eje.0.1300592  0.319
1994 Van Den Ent FMI, Van Wijnen AJ, Lian JB, Stein JL, Stein GS. Cell cycle controlled histone H1, H3, and H4 genes share unusual arrangements of recognition motifs for HiNF-D supporting a coordinate promoter binding mechanism Journal of Cellular Physiology. 159: 515-530. PMID 8188766 DOI: 10.1002/Jcp.1041590316  0.435
1994 Ramsey-Ewing AL, Wijnen AJV, Stein GS, Stein JL. Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription. Proceedings of the National Academy of Sciences of the United States of America. 91: 4475-4479. PMID 8183933 DOI: 10.1073/Pnas.91.10.4475  0.481
1994 Bortell R, Owen TA, Ignotz RA, Stein GS, Stein JL. TGFβ1 Prevents the down‐regulation of type I procollagen, fibronectin, and TGFβ1 gene expression associated with 3T3‐L1 pre‐adipocyte differentiation Journal of Cellular Biochemistry. 54: 256-263. PMID 8175900 DOI: 10.1002/Jcb.240540214  0.437
1994 Gierthy JF, Silkworth JB, Tassinari M, Stein GS, Lian JB. 2,3,7,8-Tetrachlorodibenzo-P-dioxin inhibits differentiation of normal diploid rat osteoblasts in vitro Journal of Cellular Biochemistry. 54: 231-238. PMID 8175897 DOI: 10.1002/Jcb.240540211  0.426
1994 Briggs R, Dworkin L, Briggs J, Dessypris E, Stein J, Stein G, Lian J. Interferon α selectively affects expression of the human myeloid cell nuclear differentiation antigen in late stage cells in the monocytic but not the granulocytic lineage Journal of Cellular Biochemistry. 54: 198-206. PMID 8175894 DOI: 10.1002/Jcb.240540208  0.34
1994 Bidwell J, van Wijnen A, Banerjee C, Fey E, Merriman H, Penman S, Stein J, Lian J, Stein G. Parathyroid-responsive modifications in the nuclear matrix of ROS 17/2.8 rat osteosarcoma cells. Endocrinology. 134: 1738-44. PMID 8137738 DOI: 10.1210/Endo.134.4.8137738  0.462
1994 Kockx M, McCabe L, Stein JL, Lian JB, Stein GS. Influence of DNA replication inhibition on expression of cell growth and tissue-specific genes in osteoblasts and osteosarcoma cells Journal of Cellular Biochemistry. 54: 47-55. PMID 8126086 DOI: 10.1002/Jcb.240540106  0.497
1994 Shakoori AR, Wijnen AJv, Bortell R, Owen TA, Stein JL, Lian JB, Stein GS. Variations in vitamin D receptor transcription factor complexes associated with the osteocalcin gene vitamin D responsive element in osteoblasts and osteosarcoma cells Journal of Cellular Biochemistry. 55: 218-229. PMID 8089197 DOI: 10.1002/Jcb.240550209  0.36
1994 Shalhoub V, Bortell R, Jackson ME, Marks SC, Stein JL, Lian JB, Stein GS. Transcriptionally active nuclei isolated from intact bone reflect modified levels of gene expression in skeletal development and pathology. Journal of Cellular Biochemistry. 55: 182-9. PMID 8089193 DOI: 10.1002/Jcb.240550205  0.449
1994 Stein GS, Van Wijnen AJ, Stein JL, Lian JB, Bidwell JP, Montecino M. Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation Journal of Cellular Biochemistry. 55: 4-15. PMID 8083299 DOI: 10.1002/Jcb.240550103  0.498
1994 Jenis LG, Ongphiphadhanakul B, Braverman LE, Stein GS, Lian JB, Lew R, Baran DT. Responsiveness of gene expression markers of osteoblastic and osteoclastic activity to calcitonin in the appendicular and axial skeleton of the rat in vivo Calcified Tissue International. 54: 511-515. PMID 8082057 DOI: 10.1007/Bf00334334  0.402
1994 Breen EC, Ignotz RA, McCabe LR, Stein JL, Stein GS, Lian JB. TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype. Journal of Cellular Physiology. 160: 323-335. PMID 8040190 DOI: 10.1002/Jcp.1041600214  0.352
1994 Barone LM, Aronow MA, Tassinari MS, Conlon D, Canalis E, Stein GS, Lian JB. Differential effects of warfarin on mRNA levels of developmentally regulated vitamin K dependent proteins, osteocalcin, and matrix Gla protein in vitro Journal of Cellular Physiology. 160: 255-264. PMID 8040186 DOI: 10.1002/Jcp.1041600207  0.403
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