| Year |
Citation |
Score |
| 2023 |
Evrin C, Alvarez V, Ainsworth J, Fujisawa R, Alabert C, Labib KP. DONSON is required for CMG helicase assembly in the mammalian cell cycle. Embo Reports. 24: e57677. PMID 37781960 DOI: 10.15252/embr.202357677 |
0.506 |
|
| 2023 |
Xia Y, Sonneville R, Jenkyn-Bedford M, Ji L, Alabert C, Hong Y, Yeeles JTP, Labib KPM. DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in . Science (New York, N.Y.). eadi4932. PMID 37590372 DOI: 10.1126/science.adi4932 |
0.583 |
|
| 2022 |
Evrin C, Serra-Cardona A, Duan S, Mukherjee PP, Zhang Z, Labib KPM. Spt5 histone binding activity preserves chromatin during transcription by RNA polymerase II. The Embo Journal. 41: e109783. PMID 35102600 DOI: 10.15252/embj.2021109783 |
0.35 |
|
| 2021 |
Jenkyn-Bedford M, Jones ML, Baris Y, Labib KPM, Cannone G, Yeeles JTP, Deegan TD. A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature. 600: 743-747. PMID 34700328 DOI: 10.1038/s41586-021-04145-3 |
0.566 |
|
| 2021 |
Xia Y, Fujisawa R, Deegan TD, Sonneville R, Labib KPM. TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans. The Embo Journal. e108053. PMID 34269473 DOI: 10.15252/embj.2021108053 |
0.568 |
|
| 2021 |
Le TT, Ainsworth J, Polo Rivera C, Macartney T, Labib K. Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes. The Biochemical Journal. PMID 34195792 DOI: 10.1042/BCJ20210315 |
0.375 |
|
| 2021 |
Villa F, Fujisawa R, Ainsworth J, Nishimura K, Lie-A-Ling M, Lacaud G, Labib KP. CUL2 , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle. Embo Reports. e52164. PMID 33590678 DOI: 10.15252/embr.202052164 |
0.336 |
|
| 2020 |
Deegan TD, Mukherjee PP, Fujisawa R, Polo Rivera C, Labib K. CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold. Elife. 9. PMID 32804080 DOI: 10.7554/Elife.60371 |
0.685 |
|
| 2020 |
Deegan TD, Mukherjee PP, Fujisawa R, Rivera CP, Labib K. Author response: CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold Elife. DOI: 10.7554/Elife.60371.Sa2 |
0.58 |
|
| 2019 |
Sonneville R, Bhowmick R, Hoffmann S, Mailand N, Hickson ID, Labib K. TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication. Elife. 8. PMID 31545170 DOI: 10.7554/Elife.48686 |
0.691 |
|
| 2019 |
Mukherjee PP, Labib KPM. In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast. Cell Reports. 28: 2777-2783.e4. PMID 31509741 DOI: 10.1016/j.celrep.2019.08.026 |
0.373 |
|
| 2019 |
Deegan TD, Baxter J, Ortiz Bazán MÁ, Yeeles JTP, Labib KPM. Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes. Molecular Cell. PMID 30850330 DOI: 10.1016/j.molcel.2019.01.040 |
0.578 |
|
| 2019 |
Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC. Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Molecular Cell. 73: 915-929.e6. PMID 30849395 DOI: 10.1016/J.Molcel.2018.12.021 |
0.685 |
|
| 2019 |
Sonneville R, Bhowmick R, Hoffmann S, Mailand N, Hickson ID, Labib K. Author response: TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication Elife. DOI: 10.7554/Elife.48686.017 |
0.61 |
|
| 2018 |
Gan H, Serra-Cardona A, Hua X, Zhou H, Labib K, Yu C, Zhang Z. The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands. Molecular Cell. PMID 30244834 DOI: 10.1016/J.Molcel.2018.09.001 |
0.468 |
|
| 2018 |
Evrin C, Maman JD, Diamante A, Pellegrini L, Labib K. Histone H2A-H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin. The Embo Journal. 37. PMID 30104407 DOI: 10.15252/Embj.201899021 |
0.494 |
|
| 2018 |
Hong Y, Velkova M, Silva N, Jagut M, Scheidt V, Labib K, Jantsch V, Gartner A. The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans. Plos Genetics. 14: e1007453. PMID 29879106 DOI: 10.1371/Journal.Pgen.1007453 |
0.492 |
|
| 2018 |
Hong Y, Sonneville R, Wang B, Scheidt V, Meier B, Woglar A, Demetriou S, Labib K, Jantsch V, Gartner A. LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis. Nature Communications. 9: 728. PMID 29463814 DOI: 10.1038/S41467-018-03135-W |
0.617 |
|
| 2017 |
Wu Y, Villa F, Maman J, Dobnikar L, Lau YH, Simon AC, Labib K, Spring DR, Pellegrini L. Targeting the genome stability hub Ctf4 by stapled-peptide design. Angewandte Chemie (International Ed. in English). PMID 28815832 DOI: 10.1002/Anie.201705611 |
0.411 |
|
| 2017 |
Sonneville R, Moreno SP, Knebel A, Johnson C, Hastie CJ, Gartner A, Gambus A, Labib K. CUL-2(LRR-1) and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis. Nature Cell Biology. PMID 28368371 DOI: 10.1038/Ncb3500 |
0.741 |
|
| 2017 |
Maric M, Mukherjee P, Tatham MH, Hay R, Labib K. Ufd1-Npl4 Recruit Cdc48 for Disassembly of Ubiquitylated CMG Helicase at the End of Chromosome Replication. Cell Reports. 18: 3033-3042. PMID 28355556 DOI: 10.1016/J.Celrep.2017.03.020 |
0.608 |
|
| 2016 |
Villa F, Simon AC, Ortiz Bazan MA, Kilkenny ML, Wirthensohn D, Wightman M, Matak-Vinkovíc D, Pellegrini L, Labib K. Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase. Molecular Cell. PMID 27397685 DOI: 10.1016/J.Molcel.2016.06.009 |
0.68 |
|
| 2016 |
Bell SP, Labib K. Chromosome Duplication in Saccharomyces cerevisiae. Genetics. 203: 1027-67. PMID 27384026 DOI: 10.1534/genetics.115.186452 |
0.619 |
|
| 2016 |
Buser R, Kellner V, Melnik A, Wilson-Zbinden C, Schellhaas R, Kastner L, Piwko W, Dees M, Picotti P, Maric M, Labib K, Luke B, Peter M. The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress. Plos Genetics. 12: e1005843. PMID 26849847 DOI: 10.1371/Journal.Pgen.1005843 |
0.641 |
|
| 2015 |
Maculins T, Nkosi PJ, Nishikawa H, Labib K. Tethering of SCF(Dia2) to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase. Current Biology : Cb. 25: 2254-9. PMID 26255844 DOI: 10.1016/J.Cub.2015.07.012 |
0.613 |
|
| 2015 |
García-Rodríguez LJ, De Piccoli G, Marchesi V, Jones RC, Edmondson RD, Labib K. A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1. Nucleic Acids Research. 43: 8830-8. PMID 26250113 DOI: 10.1093/Nar/Gkv799 |
0.54 |
|
| 2015 |
Sonneville R, Craig G, Labib K, Gartner A, Blow JJ. Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos. Cell Reports. 12: 405-17. PMID 26166571 DOI: 10.1016/J.Celrep.2015.06.046 |
0.749 |
|
| 2015 |
Sonneville R, Craig G, Labib K, Gartner A, Blow JJ. Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos Cell Reports. 12: 405-417. DOI: 10.1016/j.celrep.2015.06.046 |
0.508 |
|
| 2014 |
Maric M, Maculins T, De Piccoli G, Labib K. Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication. Science (New York, N.Y.). 346: 1253596. PMID 25342810 DOI: 10.1126/Science.1253596 |
0.642 |
|
| 2014 |
Simon AC, Zhou JC, Perera RL, van Deursen F, Evrin C, Ivanova ME, Kilkenny ML, Renault L, Kjaer S, Matak-Vinković D, Labib K, Costa A, Pellegrini L. A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome. Nature. 510: 293-7. PMID 24805245 DOI: 10.1038/Nature13234 |
0.585 |
|
| 2013 |
Sengupta S, van Deursen F, de Piccoli G, Labib K. Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Current Biology : Cb. 23: 543-52. PMID 23499531 DOI: 10.1016/J.Cub.2013.02.011 |
0.651 |
|
| 2013 |
Foltman M, Evrin C, De Piccoli G, Jones RC, Edmondson RD, Katou Y, Nakato R, Shirahige K, Labib K. Eukaryotic replisome components cooperate to process histones during chromosome replication. Cell Reports. 3: 892-904. PMID 23499444 DOI: 10.1016/J.Celrep.2013.02.028 |
0.558 |
|
| 2013 |
Nkosi PJ, Targosz BS, Labib K, Sanchez-Diaz A. Hof1 and Rvs167 have redundant roles in actomyosin ring function during cytokinesis in budding yeast. Plos One. 8: e57846. PMID 23469085 DOI: 10.1371/Journal.Pone.0057846 |
0.37 |
|
| 2012 |
Devrekanli A, Foltman M, Roncero C, Sanchez-Diaz A, Labib K. Inn1 and Cyk3 regulate chitin synthase during cytokinesis in budding yeasts. Journal of Cell Science. 125: 5453-66. PMID 22956544 DOI: 10.1242/Jcs.109157 |
0.341 |
|
| 2012 |
Sanchez-Diaz A, Nkosi PJ, Murray S, Labib K. The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth. The Embo Journal. 31: 3620-34. PMID 22872148 DOI: 10.1038/Emboj.2012.224 |
0.329 |
|
| 2012 |
Kilkenny ML, De Piccoli G, Perera RL, Labib K, Pellegrini L. A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome Journal of Biological Chemistry. 287: 23740-23747. PMID 22593576 DOI: 10.1074/Jbc.M112.368951 |
0.541 |
|
| 2012 |
van Deursen F, Sengupta S, De Piccoli G, Sanchez-Diaz A, Labib K. Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation. The Embo Journal. 31: 2195-206. PMID 22433841 DOI: 10.1038/Emboj.2012.69 |
0.675 |
|
| 2012 |
De Piccoli G, Katou Y, Itoh T, Nakato R, Shirahige K, Labib K. Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Molecular Cell. 45: 696-704. PMID 22325992 DOI: 10.1016/J.Molcel.2012.01.007 |
0.623 |
|
| 2011 |
Labib K. Building a double hexamer of DNA helicase at eukaryotic replication origins. The Embo Journal. 30: 4853-5. PMID 22166996 DOI: 10.1038/Emboj.2011.437 |
0.636 |
|
| 2011 |
Labib K, De Piccoli G. Surviving chromosome replication: the many roles of the S-phase checkpoint pathway. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 3554-61. PMID 22084382 DOI: 10.1098/Rstb.2011.0071 |
0.663 |
|
| 2010 |
Labib K. How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells? Genes & Development. 24: 1208-19. PMID 20551170 DOI: 10.1101/Gad.1933010 |
0.587 |
|
| 2009 |
Morohashi H, Maculins T, Labib K. The amino-terminal TPR domain of Dia2 tethers SCF(Dia2) to the replisome progression complex. Current Biology : Cb. 19: 1943-9. PMID 19913425 DOI: 10.1016/J.Cub.2009.09.062 |
0.564 |
|
| 2009 |
Gambus A, van Deursen F, Polychronopoulos D, Foltman M, Jones RC, Edmondson RD, Calzada A, Labib K. A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. The Embo Journal. 28: 2992-3004. PMID 19661920 DOI: 10.1038/Emboj.2009.226 |
0.801 |
|
| 2008 |
de la Cueva-Mendez G, Labib K. New insights into the chromosome cycle. Conference on the Replication & Segregation of Chromosomes. Embo Reports. 9: 1177-81. PMID 18974771 DOI: 10.1038/Embor.2008.203 |
0.497 |
|
| 2008 |
Labib K. Making connections at DNA replication forks: Mrc1 takes the lead. Molecular Cell. 32: 166-8. PMID 18951084 DOI: 10.1016/J.Molcel.2008.10.005 |
0.607 |
|
| 2008 |
Sanchez-Diaz A, Marchesi V, Murray S, Jones R, Pereira G, Edmondson R, Allen T, Labib K. Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast. Nature Cell Biology. 10: 395-406. PMID 18344988 DOI: 10.1038/Ncb1701 |
0.306 |
|
| 2007 |
Hodgson B, Calzada A, Labib K. Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase Molecular Biology of the Cell. 18: 3894-3902. PMID 17652453 DOI: 10.1091/Mbc.E07-05-0500 |
0.706 |
|
| 2007 |
Labib K, Gambus A. A key role for the GINS complex at DNA replication forks. Trends in Cell Biology. 17: 271-8. PMID 17467990 DOI: 10.1016/J.Tcb.2007.04.002 |
0.804 |
|
| 2007 |
Labib K, Hodgson B. Replication fork barriers: Pausing for a break or stalling for time? Embo Reports. 8: 346-353. PMID 17401409 DOI: 10.1038/Sj.Embor.7400940 |
0.706 |
|
| 2006 |
Kanemaki M, Labib K. Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks. The Embo Journal. 25: 1753-63. PMID 16601689 DOI: 10.1038/Sj.Emboj.7601063 |
0.739 |
|
| 2006 |
Gambus A, Jones RC, Sanchez-Diaz A, Kanemaki M, van Deursen F, Edmondson RD, Labib K. GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nature Cell Biology. 8: 358-66. PMID 16531994 DOI: 10.1038/Ncb1382 |
0.801 |
|
| 2005 |
Calzada A, Hodgson B, Kanemaki M, Bueno A, Labib K. Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork Genes and Development. 19: 1905-1919. PMID 16103218 DOI: 10.1101/Gad.337205 |
0.706 |
|
| 2004 |
Sanchez-Diaz A, Kanemaki M, Marchesi V, Labib K. Rapid depletion of budding yeast proteins by fusion to a heat-inducible degron. Science's Stke : Signal Transduction Knowledge Environment. 2004: PL8. PMID 15010550 DOI: 10.1126/Stke.2232004Pl8 |
0.398 |
|
| 2003 |
Kanemaki M, Sanchez-Diaz A, Gambus A, Labib K. Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo. Nature. 423: 720-4. PMID 12768207 DOI: 10.1038/Nature01692 |
0.745 |
|
| 2002 |
Diffley JF, Labib K. The chromosome replication cycle. Journal of Cell Science. 115: 869-72. PMID 11870205 |
0.323 |
|
| 2001 |
Labib K, Kearsey SE, Diffley JF. MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint. Molecular Biology of the Cell. 12: 3658-67. PMID 11694596 DOI: 10.1091/Mbc.12.11.3658 |
0.52 |
|
| 2001 |
Labib K, Diffley JF. Is the MCM2-7 complex the eukaryotic DNA replication fork helicase? Current Opinion in Genetics & Development. 11: 64-70. PMID 11163153 DOI: 10.1016/S0959-437X(00)00158-1 |
0.697 |
|
| 2000 |
Diffley JF, Bousset K, Labib K, Noton EA, Santocanale C, Tercero JA. Coping with and recovering from hydroxyurea-induced replication fork arrest in budding yeast. Cold Spring Harbor Symposia On Quantitative Biology. 65: 333-42. PMID 12760047 DOI: 10.1101/Sqb.2000.65.333 |
0.478 |
|
| 2000 |
Labib K, Tercero JA, Diffley JF. Uninterrupted MCM2-7 function required for DNA replication fork progression. Science (New York, N.Y.). 288: 1643-7. PMID 10834843 DOI: 10.1126/Science.288.5471.1643 |
0.675 |
|
| 2000 |
Tercero JA, Labib K, Diffley JF. DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p. The Embo Journal. 19: 2082-93. PMID 10790374 DOI: 10.1093/Emboj/19.9.2082 |
0.627 |
|
| 2000 |
Kearsey SE, Montgomery S, Labib K, Lindner K. Chromatin binding of the fission yeast replication factor mcm4 occurs during anaphase and requires ORC and cdc18 The Embo Journal. 19: 1681-1690. PMID 10747035 DOI: 10.1093/Emboj/19.7.1681 |
0.582 |
|
| 1999 |
Labib K, Diffley JF, Kearsey SE. G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus. Nature Cell Biology. 1: 415-22. PMID 10559985 DOI: 10.1038/15649 |
0.481 |
|
| 1998 |
Kearsey SE, Labib K. MCM proteins: evolution, properties, and role in DNA replication. Biochimica Et Biophysica Acta. 1398: 113-136. PMID 9689912 DOI: 10.1016/S0167-4781(98)00033-5 |
0.514 |
|
| 1996 |
Kearsey SE, Labib K, Maiorano D. Cell cycle control of eukaryotic DNA replication. Current Opinion in Genetics & Development. 6: 208-14. PMID 8722178 DOI: 10.1016/S0959-437X(96)80052-9 |
0.502 |
|
| 1992 |
Waseem N, Labib K, Nurse P, Lane D. Isolation and analysis of the fission yeast gene encoding polymerase delta accessory protein PCNA. The Embo Journal. 11: 5111-5120. DOI: 10.1002/J.1460-2075.1992.Tb05618.X |
0.405 |
|
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