Timothy Fyfe - Publications
Affiliations: | 2015-2019 | Pharmacy/MIPS | University of Nottingham/Monash University |
Year | Citation | Score | |||
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2021 | Fyfe TJ, Scammells PJ, Lane JR, Capuano B. Enantioenriched Positive Allosteric Modulators Display Distinct Pharmacology at the Dopamine D Receptor. Molecules (Basel, Switzerland). 26. PMID 34206465 DOI: 10.3390/molecules26133799 | 0.732 | |||
2019 | Fyfe TJ, Kellam B, Sykes DA, Capuano B, Scammells PJ, Lane JR, Charlton SJ, Mistry SN. Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D Receptor. Journal of Medicinal Chemistry. PMID 31580666 DOI: 10.1021/Acs.Jmedchem.9B00864 | 0.614 | |||
2019 | Fyfe TJ, Kellam B, Mistry SN, Scammells PJ, Lane JR, Capuano B. Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D receptor. European Journal of Medicinal Chemistry. 168: 474-490. PMID 30849613 DOI: 10.1016/J.Ejmech.2019.01.061 | 0.632 | |||
2018 | Luderman KD, Conroy JL, Free RB, Southall N, Ferrer M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aube J, Lane JR, Frankowski KJ, et al. Identification of positive allosteric modulators of the D1 dopamine receptor that act at diverse binding sites. Molecular Pharmacology. PMID 30068735 DOI: 10.1124/Mol.118.113175 | 0.667 | |||
2018 | Fyfe TJ, Zarzycka B, Lim HD, Kellam B, Mistry SN, Katritch V, Scammells PJ, Lane JR, Capuano B. A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor. Journal of Medicinal Chemistry. PMID 29683325 DOI: 10.1021/Acs.Jmedchem.7B01565 | 0.635 | |||
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