Alexander J. Federation - Publications

Affiliations: 
2016-2019 Genome Sciences University of Washington, Seattle, Seattle, WA 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Federation AJ, Nandakumar V, Searle BC, Stergachis A, Wang H, Pino LK, Merrihew G, Ting YS, Howard N, Kutyavin T, MacCoss MJ, Stamatoyannopoulos JA. Highly Parallel Quantification and Compartment Localization of Transcription Factors and Nuclear Proteins. Cell Reports. 30: 2463-2471.e5. PMID 32101728 DOI: 10.1016/J.Celrep.2020.01.096  0.377
2020 Lazarchuk P, Hernandez-Villanueva J, Pavlova MN, Federation A, MacCoss M, Sidorova JM. Mutual Balance of Histone Deacetylases 1 and 2 and the Acetyl Reader ATAD2 Regulates the Level of Acetylation of Histone H4 on Nascent Chromatin of Human Cells. Molecular and Cellular Biology. 40. PMID 32015101 DOI: 10.1128/Mcb.00421-19  0.606
2018 Ott CJ, Federation AJ, Schwartz LS, Kasar S, Klitgaard JL, Lenci R, Li Q, Lawlor M, Fernandes SM, Souza A, Polaski D, Gadi D, Freedman ML, Brown JR, Bradner JE. Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia. Cancer Cell. PMID 30503705 DOI: 10.1016/J.Ccell.2018.11.001  0.527
2018 Zhang Y, Federation AJ, Kim S, O'Keefe JP, Lun M, Xiang D, Brown JD, Steinhauser ML. Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity. The Journal of Clinical Investigation. PMID 30277475 DOI: 10.1172/Jci98353  0.352
2018 Brown JD, Feldman ZB, Doherty SP, Reyes JM, Rahl PB, Lin CY, Sheng Q, Duan Q, Federation AJ, Kung AL, Haldar SM, Young RA, Plutzky J, Bradner JE. BET bromodomain proteins regulate enhancer function during adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29444854 DOI: 10.1073/Pnas.1711155115  0.528
2017 Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, et al. Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature. PMID 29258295 DOI: 10.1038/Nature25169  0.404
2017 Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, et al. Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. Plos Pathogens. 13: e1006668. PMID 29028833 DOI: 10.1371/Journal.Ppat.1006668  0.476
2016 Zhang H, Qi J, Reyes JM, Li L, Rao PK, Li F, Lin CY, Perry JA, Lawlor MA, Federation A, De Raedt T, Li YY, Liu Y, Duarte MA, Zhang Y, et al. Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer. Cancer Discovery. PMID 27312177 DOI: 10.1158/2159-8290.Cd-16-0164  0.33
2016 Saint-André V, Federation AJ, Lin CY, Abraham BJ, Reddy J, Lee TI, Bradner JE, Young RA. Models of human core transcriptional regulatory circuitries. Genome Research. PMID 26843070 DOI: 10.1101/Gr.197590.115  0.465
2016 Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, ... ... Federation A, et al. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nature Genetics. PMID 26829751 DOI: 10.1038/Ng.3500  0.325
2016 Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature. PMID 26814967 DOI: 10.1038/Nature16546  0.519
2015 Pefanis E, Wang J, Rothschild G, Lim J, Kazadi D, Sun J, Federation A, Chao J, Elliott O, Liu ZP, Economides AN, Bradner JE, Rabadan R, Basu U. RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity. Cell. 161: 774-89. PMID 25957685 DOI: 10.1016/J.Cell.2015.04.034  0.373
2015 Ott CJ, Federation AJ, Kasar S, Klitgaard JL, Fernandes SM, Brown JR, Bradner JE. Enhancer Landscapes Reveal Transcription Factor Network Dependencies in Chronic Lymphocytic Leukemia Blood. 126: 436-436. DOI: 10.1182/Blood.V126.23.436.436  0.547
2015 Lin CY, Erkek S, Tong Y, Yang L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz H, Worst B, Ju B, Orr BA, Zeid R, Polaski DR, et al. Abstract LB-B23: Medulloblastoma regulatory circuitries reveal subgroup-specific cellular origins Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-B23  0.469
2014 Meng FL, Du Z, Federation A, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig MC, Bradner JE, Liu XS, Alt FW. Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability. Cell. 159: 1538-48. PMID 25483776 DOI: 10.1016/J.Cell.2014.11.014  0.403
2014 Brown JD, Lin CY, Duan Q, Griffin G, Federation AJ, Paranal RM, Bair S, Newton G, Lichtman AH, Kung AL, Yang T, Wang H, Luscinskas FW, Croce KJ, Bradner JE, et al. NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis. Molecular Cell. 56: 219-31. PMID 25263595 DOI: 10.1016/J.Molcel.2014.08.024  0.522
2014 Federation AJ, Bradner JE, Meissner A. The use of small molecules in somatic-cell reprogramming. Trends in Cell Biology. 24: 179-87. PMID 24183602 DOI: 10.1016/J.Tcb.2013.09.011  0.386
2012 Yu W, Chory EJ, Wernimont AK, Tempel W, Scopton A, Federation A, Marineau JJ, Qi J, Barsyte-Lovejoy D, Yi J, Marcellus R, Iacob RE, Engen JR, Griffin C, Aman A, et al. Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nature Communications. 3: 1288. PMID 23250418 DOI: 10.1038/Ncomms2304  0.363
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