Steven Jacobson - Publications

Affiliations: 
NINDS National Institutes of Health, Bethesda, MD 

257 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Monaco MCG, Soldan SS, Su C, Clauze A, Cooper JF, Patel RJ, Lu F, Hughes RJ, Messick TE, Andrada FC, Ohayon J, Lieberman PM, Jacobson S. EBNA1 Inhibitors Block Proliferation of Spontaneous Lymphoblastoid Cell Lines From Patients With Multiple Sclerosis and Healthy Controls. Neurology(R) Neuroimmunology & Neuroinflammation. 10. PMID 37562974 DOI: 10.1212/NXI.0000000000200149  0.654
2023 Enose-Akahata Y, Wang L, Almsned F, Johnson KR, Mina Y, Ohayon J, Wang XW, Jacobson S. The repertoire of CSF antiviral antibodies in patients with neuroinflammatory diseases. Science Advances. 9: eabq6978. PMID 36598996 DOI: 10.1126/sciadv.abq6978  0.332
2022 Clauze A, Enose-Akahata Y, Jacobson S. T cell receptor repertoire analysis in HTLV-1-associated diseases. Frontiers in Immunology. 13: 984274. PMID 36189294 DOI: 10.3389/fimmu.2022.984274  0.372
2021 Middleton DM, Shahrampour S, Krisa L, Liu W, Nair G, Jacobson S, Conklin CJ, Alizadeh M, Faro SH, Mulcahey MJ, Mohamed FB. Correlations of diffusion tensor imaging and clinical measures with spinal cord cross-sectional area measurements in pediatric spinal cord injury patients. The Journal of Spinal Cord Medicine. 1-8. PMID 34855576 DOI: 10.1080/10790268.2021.1997027  0.745
2021 Enose-Akahata Y, Billioux BJ, Azodi S, Dwyer J, Vellucci A, Ngouth N, Nozuma S, Massoud R, Cortese I, Ohayon J, Jacobson S. Clinical trial of raltegravir, an integrase inhibitor, in HAM/TSP. Annals of Clinical and Translational Neurology. PMID 34562313 DOI: 10.1002/acn3.51437  0.308
2021 Cortese I, Beck ES, Al-Louzi O, Ohayon J, Andrada F, Osuorah I, Dwyer J, Billioux BJ, Dargah-Zada N, Schindler MK, Binder K, Reoma L, Norato G, Enose-Akahata Y, Smith BR, ... ... Jacobson S, et al. BK virus-specific T cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study. The Lancet. Neurology. 20: 639-652. PMID 34302788 DOI: 10.1016/S1474-4422(21)00174-5  0.328
2021 Enose-Akahata Y, Ngouth N, Ohayon J, Mandel M, Chavin J, Turner TJ, Jacobson S. Effect of Teriflunomide on Cells From Patients With Human T-cell Lymphotropic Virus Type 1-Associated Neurologic Disease. Neurology(R) Neuroimmunology & Neuroinflammation. 8. PMID 33837058 DOI: 10.1212/NXI.0000000000000986  0.341
2021 Nozuma S, Enose-Akahata Y, Johnson KR, Monaco MC, Ngouth N, Elkahloun A, Ohayon J, Zhu J, Jacobson S. Immunopathogenic CSF TCR repertoire signatures in virus-associated neurologic disease. Jci Insight. 6. PMID 33616082 DOI: 10.1172/jci.insight.144869  0.314
2020 Akinsoji EO, Leibovitch E, Billioux BJ, Abath Neto OL, Ray-Chaudhury A, Inati SK, Zaghloul K, Heiss J, Jacobson S, Theodore WH. HHV-6 and hippocampal volume in patients with mesial temporal sclerosis. Annals of Clinical and Translational Neurology. 7: 1674-1680. PMID 33325656 DOI: 10.1002/Acn3.51152  0.347
2020 Schindler MK, Pittaluga S, Enose-Akahata Y, Su HC, Rao VK, Rump A, Jacobson S, Cortese I, Reich DS, Uzel G. Haploinsufficiency of immune checkpoint receptor CTLA4 induces a distinct neuroinflammatory disorder. The Journal of Clinical Investigation. PMID 32955488 DOI: 10.1172/Jci135947  0.35
2020 Donadieu M, Kelly H, Szczupak D, Lin JP, Song Y, Yen CCC, Ye FQ, Kolb H, Guy JR, Beck ES, Jacobson S, Silva AC, Sati P, Reich DS. Ultrahigh-resolution MRI Reveals Extensive Cortical Demyelination in a Nonhuman Primate Model of Multiple Sclerosis. Cerebral Cortex (New York, N.Y. : 1991). PMID 32901254 DOI: 10.1093/Cercor/Bhaa235  0.302
2020 Maggi P, Sati P, Nair G, Cortese ICM, Jacobson S, Smith BR, Nath A, Ohayon J, van Pesch V, Perrotta G, Pot C, Théaudin M, Martinelli V, Scotti R, Wu T, et al. PARAMAGNETIC RIM LESIONS ARE SPECIFIC TO MULTIPLE SCLEROSIS: AN INTERNATIONAL MULTICENTER 3T MRI STUDY. Annals of Neurology. PMID 32799417 DOI: 10.1002/Ana.25877  0.353
2020 Nozuma S, Kubota R, Jacobson S. Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis. Journal of Neurovirology. PMID 32705480 DOI: 10.1007/S13365-020-00881-W  0.479
2020 Allnutt MA, Johnson K, Bennett DA, Connor SM, Troncoso JC, Pletnikova O, Albert MS, Resnick SM, Scholz SW, De Jager PL, Jacobson S. Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts. Neuron. PMID 31983538 DOI: 10.1016/J.Neuron.2019.12.031  0.308
2019 Enose-Akahata Y, Jacobson S. Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology. 16: 35. PMID 31783764 DOI: 10.1186/S12977-019-0499-5  0.459
2019 Enose-Akahata Y, Oh U, Ohayon J, Billioux BJ, Massoud R, Bryant BR, Vellucci A, Ngouth N, Cortese I, Waldmann TA, Jacobson S. Clinical trial of a humanized anti-IL-2/IL-15 receptor β chain in HAM/TSP. Annals of Clinical and Translational Neurology. 6: 1383-1394. PMID 31402625 DOI: 10.1002/Acn3.50820  0.326
2019 Galli V, Nixon CC, Strbo N, Artesi M, de Castro-Amarante MF, McKinnon K, Fujikawa D, Omsland M, Washington-Parks R, Romero L, Caruso B, Durkin K, Brown S, Karim B, Vaccari M, ... Jacobson S, et al. Essential Role of HTLV-1 in Lethal Proliferation of CD4 Cells in Humanized Mice. Journal of Virology. PMID 31315992 DOI: 10.1128/Jvi.00565-19  0.354
2019 Nozuma S, Jacobson S. Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis. Frontiers in Microbiology. 10: 885. PMID 31105674 DOI: 10.3389/Fmicb.2019.00885  0.484
2019 Pleet ML, DeMarino C, Stonier SW, Dye JM, Jacobson S, Aman MJ, Kashanchi F. Extracellular Vesicles and Ebola Virus: A New Mechanism of Immune Evasion. Viruses. 11. PMID 31052499 DOI: 10.3390/V11050410  0.393
2019 Bartolini L, Theodore WH, Jacobson S, Gaillard WD. Infection with HHV-6 and its role in epilepsy. Epilepsy Research. 153: 34-39. PMID 30953871 DOI: 10.1016/J.Eplepsyres.2019.03.016  0.361
2019 Absinta M, Nair G, Monaco MCG, Maric D, Lee NJ, Ha SK, Luciano NJ, Sati P, Jacobson S, Reich DS. THE "CENTRAL VEIN SIGN" IN INFLAMMATORY DEMYELINATION: THE ROLE OF FIBRILLAR COLLAGEN TYPE I. Annals of Neurology. PMID 30847935 DOI: 10.1002/Ana.25461  0.304
2019 Lefeuvre JA, Guy JR, Luciano NJ, Ha SK, Leibovitch E, Santin MD, Silva AC, Jacobson S, Lehéricy S, Reich DS, Sati P. The spectrum of spinal cord lesions in a primate model of multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518822408. PMID 30730246 DOI: 10.1177/1352458518822408  0.316
2019 Alves Sousa AP, Johnson KR, Ohayon J, Zhu J, Muraro PA, Jacobson S. Comprehensive Analysis of TCR-β Repertoire in Patients with Neurological Immune-mediated Disorders. Scientific Reports. 9: 344. PMID 30674904 DOI: 10.1038/S41598-018-36274-7  0.432
2019 Allnutt MA, Jacobson S. Do herpesviruses play a role in Alzheimer’s disease pathogenesis? Drug Discovery Today: Disease Models. DOI: 10.1016/J.Ddmod.2019.10.006  0.305
2018 Leibovitch EC, Jacobson S. Reply to Zahednasab et al.: HHV-6 and marmoset EAE. Proceedings of the National Academy of Sciences of the United States of America. 115: E12127. PMID 30538192 DOI: 10.1073/Pnas.1818755115  0.303
2018 Leibovitch EC, Caruso B, Ha SK, Schindler MK, Lee NJ, Luciano NJ, Billioux BJ, Guy JR, Yen C, Sati P, Silva AC, Reich DS, Jacobson S. Herpesvirus trigger accelerates neuroinflammation in a nonhuman primate model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30322946 DOI: 10.1073/Pnas.1811974115  0.455
2018 Anderson MR, Pleet ML, Enose-Akahata Y, Erickson J, Monaco MC, Akpamagbo Y, Velluci A, Tanaka Y, Azodi S, Lepene B, Jones J, Kashanchi F, Jacobson S. Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes. Clinical and Translational Medicine. 7: 24. PMID 30146667 DOI: 10.1186/S40169-018-0204-7  0.463
2018 Bartolini L, Libbey JE, Ravizza T, Fujinami RS, Jacobson S, Gaillard WD. Viral Triggers and Inflammatory Mechanisms in Pediatric Epilepsy. Molecular Neurobiology. PMID 29978423 DOI: 10.1007/S12035-018-1215-5  0.311
2018 Enose-Akahata Y, Azodi S, Smith BR, Billioux BJ, Vellucci A, Ngouth N, Tanaka Y, Ohayon J, Cortese I, Nath A, Jacobson S. Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases. Plos Pathogens. 14: e1007042. PMID 29709026 DOI: 10.1371/Journal.Ppat.1007042  0.494
2018 Lee NJ, Ha SK, Sati P, Absinta M, Luciano NJ, Lefeuvre JA, Schindler MK, Leibovitch EC, Ryu JK, Petersen MA, Silva AC, Jacobson S, Akassoglou K, Reich DS. Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination. Brain : a Journal of Neurology. PMID 29688408 DOI: 10.1093/Brain/Awy082  0.303
2018 Anderson M, Kashanchi F, Jacobson S. Role of Exosomes in Human Retroviral Mediated Disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 29656370 DOI: 10.1007/S11481-018-9784-7  0.362
2018 Leibovitch EC, Lin CM, Billioux BJ, Graves J, Waubant E, Jacobson S. Prevalence of salivary human herpesviruses in pediatric multiple sclerosis cases and controls. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518765654. PMID 29569515 DOI: 10.1177/1352458518765654  0.409
2018 Huey DD, Bolon B, La Perle KMD, Kannian P, Jacobson S, Ratner L, Green PL, Niewiesk S. Role of Wild-type and Recombinant Human T-cell Leukemia Viruses in Lymphoproliferative Disease in Humanized NSG Mice. Comparative Medicine. 68: 4-14. PMID 29460716  0.368
2018 Leibovitch EC, Jacobson S. Viruses in chronic progressive neurologic disease. Multiple Sclerosis (Houndmills, Basingstoke, England). 24: 48-52. PMID 29307291 DOI: 10.1177/1352458517737392  0.425
2017 Enose-Akahata Y, Vellucci A, Jacobson S. Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP. Frontiers in Microbiology. 8: 2563. PMID 29312243 DOI: 10.3389/Fmicb.2017.02563  0.453
2017 Azodi S, Nair G, Enose-Akahata Y, Charlip E, Vellucci A, Cortese I, Dwyer J, Billioux BJ, Chevaz T, Ohayon J, Reich DS, Jacobson S. Imaging Spinal Cord Atrophy in Progressive Myelopathies: HTLV-I Associated Neurologic Disease (HAM/TSP) and Multiple Sclerosis (MS). Annals of Neurology. PMID 29024167 DOI: 10.1002/Ana.25072  0.315
2017 Ginwala R, Caruso B, Khan ZK, Pattekar A, Chew GM, Corley MJ, Loonawat R, Jacobson S, Sreedhar S, Ndhlovu LC, Jain P. HTLV-1 Infection and Neuropathogenesis in the Context of Rag1(-/-)γc(-/-) (RAG1-Hu) and BLT Mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 28374110 DOI: 10.1007/S11481-017-9740-Y  0.405
2016 Willems L, Hasegawa H, Accolla R, Bangham C, Bazarbachi A, Bertazzoni U, Carneiro-Proietti AB, Cheng H, Chieco-Bianchi L, Ciminale V, Coelho-Dos-Reis J, Esparza J, Gallo RC, Gessain A, Gotuzzo E, ... ... Jacobson S, et al. Reducing the global burden of HTLV-1 infection: An agenda for research and action. Antiviral Research. PMID 27840202 DOI: 10.1016/J.Antiviral.2016.10.015  0.393
2016 Matsuura E, Enose-Akahata Y, Yao K, Oh U, Tanaka Y, Takashima H, Jacobson S. Dynamic acquisition of HTLV-1 tax protein by mononuclear phagocytes: Role in neurologic disease. Journal of Neuroimmunology. PMID 27769524 DOI: 10.1016/J.Jneuroim.2016.09.014  0.465
2016 Barreto FK, Khouri R, de Almeida Rego FF, Santos LA, de Castro-Amarante MF, Bialuk I, Pise-Masison CA, Galvão-Castro B, Gessain A, Jacobson S, Franchini G, Carlos L. Analyses of HTLV-1 sequences suggest interaction between ORF-I mutations and HAM/TSP outcome. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 27553711 DOI: 10.1016/J.Meegid.2016.08.020  0.326
2016 de Paula Alves Sousa A, Johnson KR, Nicholas R, Darko S, Price DA, Douek DC, Jacobson S, Muraro PA. Intrathecal T-cell clonal expansions in patients with multiple sclerosis. Annals of Clinical and Translational Neurology. 3: 422-33. PMID 27547770 DOI: 10.1002/Acn3.310  0.429
2016 Enose-Akahata Y, Caruso B, Haner B, Charlip E, Nair G, Massoud R, Billioux BJ, Ohayon J, Switzer WM, Jacobson S. Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1). Retrovirology. 13: 56. PMID 27519553 DOI: 10.1186/S12977-016-0290-9  0.455
2016 Lin CT, Leibovitch EC, Almira-Suarez MI, Jacobson S. Human herpesvirus multiplex ddPCR detection in brain tissue from low- and high-grade astrocytoma cases and controls. Infectious Agents and Cancer. 11: 32. PMID 27462365 DOI: 10.1186/S13027-016-0081-X  0.35
2016 Anderson MR, Kashanchi F, Jacobson S. Exosomes in Viral Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27324390 DOI: 10.1007/S13311-016-0450-6  0.384
2015 de Castro-Amarante MF, Pise-Masison CA, McKinnon K, Washington Parks R, Galli V, Omsland M, Andresen V, Massoud R, Brunetto G, Caruso B, Venzon D, Jacobson S, Franchini G. HTLV-1 infection of the three monocyte subsets contributes to viral burden in humans. Journal of Virology. PMID 26608313 DOI: 10.1128/Jvi.02735-15  0.436
2015 Massoud R, Enose-Akahata Y, Tagaya Y, Azimi N, Basheer A, Jacobson S. Common γ-chain blocking peptide reduces in vitro immune activation markers in HTLV-1-associated myelopathy/tropical spastic paraparesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 11030-5. PMID 26283355 DOI: 10.1073/Pnas.1412626112  0.369
2015 Enose-Akahata Y, Massoud R, Caruso B, Ohayon J, Billioux BJ, Geldern Gv, Smith B, Nath A, Jacobson S. Immunophenotyping of cerebrospinal fluid cells in virus-associated neurologic diseases. Retrovirology. 12: 86. DOI: 10.1186/1742-4690-12-S1-P86  0.477
2015 Castro-Amarante MF, Pise-Masison CA, McKinnon K, Parks RW, Galli V, Massoud R, Brunetto G, Caruso B, Venzon D, Jacobson S, Franchini G. HTLV-1 burden dependent on hijacking monocytes chemotaxis Retrovirology. 12: 7. DOI: 10.1186/1742-4690-12-S1-P7  0.397
2015 Barreto FK, Khouri R, Rego FFdA, Castro-Amarante MFd, Bialuk I, Pise-Masison CA, Galvão-Castro B, Gessain A, Jacobson S, Franchini G, Alcantara LC. ORFI genetic polymorphisms in geographically distinct HTLV-1 infections Retrovirology. 12: 55. DOI: 10.1186/1742-4690-12-S1-P55  0.347
2015 Araya N, Sato T, Tomaru U, Coler-Reilly A, Yagishita N, Yamauchi J, Hasegawa A, Kannagi M, Akiyama H, Hasegawa Y, Takahashi K, Kunitomo Y, Tanaka Y, Utsunomiya A, Jacobson S, et al. HTLV-1 Tax induces Th1 master regulator T-bet and thus IFN-γ in CD4+CCR4+ T-cells of virus-associated myelopathy patients Retrovirology. 12: 44. DOI: 10.1186/1742-4690-12-S1-P44  0.444
2015 Charlip E, Liu W, Massoud R, Billioux J, Caruso B, Ohayon J, Nair G, Jacobson S. Patterns of spinal cord atrophy in HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP) Retrovirology. 12: 32. DOI: 10.1186/1742-4690-12-S1-P32  0.314
2015 Pise-Masison CA, Nixon CC, de Castro Amarante MF, Parks RW, McKinnon K, Caruso B, Galli V, Jacobson S, Zack J, Franchini G. Detection of HTLV-1 replication and CD4+ proliferation in the humanized BLT mouse model Retrovirology. 12. DOI: 10.1186/1742-4690-12-S1-O39  0.328
2015 Enose-Akahata Y, Caruso B, Haner B, Massoud R, Billioux BJ, Ohayon J, Switzer WM, Jacobson S. Development of HTLV-1 associated myelopathy/tropical spastic paraparesis in a patient with simian T-lymphotropic virus type 1-like infection. Retrovirology. 12: 1-1. DOI: 10.1186/1742-4690-12-S1-O30  0.473
2015 Sousa AdPA, Johnson KR, Ohayon J, Zhu J, Muraro P, Jacobson S. Deep sequencing of the TCRβ repertoire reveals T cell clonal expansion is associated with HTLV-1 proviral load in HAM/TSP patients. Retrovirology. 12: 1-1. DOI: 10.1186/1742-4690-12-S1-O21  0.406
2014 Leibovitch EC, Jacobson S. Evidence linking HHV-6 with multiple sclerosis: an update. Current Opinion in Virology. 9: 127-133. PMID 25462444 DOI: 10.1016/J.Coviro.2014.09.016  0.416
2014 Pise-Masison CA, de Castro-Amarante MF, Enose-Akahata Y, Buchmann RC, Fenizia C, Washington Parks R, Edwards D, Fiocchi M, Alcantara LC, Bialuk I, Graham J, Walser JC, McKinnon K, Galvão-Castro B, Gessain A, ... ... Jacobson S, et al. Co-dependence of HTLV-1 p12 and p8 functions in virus persistence. Plos Pathogens. 10: e1004454. PMID 25375128 DOI: 10.1371/Journal.Ppat.1004454  0.367
2014 Martin F, Taylor GP, Jacobson S. Inflammatory manifestations of HTLV-1 and their therapeutic options. Expert Review of Clinical Immunology. 10: 1531-46. PMID 25340428 DOI: 10.1586/1744666X.2014.966690  0.419
2014 Liu W, Nair G, Vuolo L, Bakshi A, Massoud R, Reich DS, Jacobson S. In vivo imaging of spinal cord atrophy in neuroinflammatory diseases. Annals of Neurology. 76: 370-8. PMID 25042583 DOI: 10.1002/Ana.24213  0.784
2014 Araya N, Sato T, Ando H, Tomaru U, Yoshida M, Coler-Reilly A, Yagishita N, Yamauchi J, Hasegawa A, Kannagi M, Hasegawa Y, Takahashi K, Kunitomo Y, Tanaka Y, Nakajima T, ... ... Jacobson S, et al. HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells. The Journal of Clinical Investigation. 124: 3431-42. PMID 24960164 DOI: 10.1172/Jci75250  0.404
2014 Anderson MR, Enose-Akahata Y, Massoud R, Ngouth N, Tanaka Y, Oh U, Jacobson S. Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 522-32. PMID 24845974 DOI: 10.1007/S11481-014-9547-Z  0.387
2014 Brunetto GS, Massoud R, Leibovitch EC, Caruso B, Johnson K, Ohayon J, Fenton K, Cortese I, Jacobson S. Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP patients and identification of viral mutations Journal of Neurovirology. 20: 341-351. PMID 24781526 DOI: 10.1007/S13365-014-0249-3  0.405
2014 Leibovitch EC, Brunetto GS, Caruso B, Fenton K, Ohayon J, Reich DS, Jacobson S. Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. Plos One. 9: e92328. PMID 24663487 DOI: 10.1371/Journal.Pone.0092328  0.364
2014 Gaitán MI, Maggi P, Wohler J, Leibovitch E, Sati P, Calandri IL, Merkle H, Massacesi L, Silva AC, Jacobson S, Reich DS. Perivenular brain lesions in a primate multiple sclerosis model at 7-tesla magnetic resonance imaging. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 64-71. PMID 23773983 DOI: 10.1177/1352458513492244  0.316
2014 Virtanen JO, Wohler J, Fenton K, Reich DS, Jacobson S. Oligoclonal bands in multiple sclerosis reactive against two herpesviruses and association with magnetic resonance imaging findings. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 27-34. PMID 23722324 DOI: 10.1177/1352458513490545  0.428
2014 Liu W, Bakshi A, Massoud R, Brunetto GS, Reich DS, Nair G, Jacobson S. Quantifying spinal cord cross-sectional area in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) Retrovirology. 11: 22. DOI: 10.1186/1742-4690-11-S1-P22  0.328
2014 Yamano Y, Sato T, Ando H, Araya N, Yagishita N, Yamauchi J, Coler-Reilly A, Utsunomiya A, Jacobson S, Izumo S. CXCL10 and neopterin in CSF are candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis Retrovirology. 11: 18. DOI: 10.1186/1742-4690-11-S1-P18  0.373
2014 Massoud R, Enose-Akahata Y, Tagaya Y, Azimi N, Jacobson S. BNZ-gamma peptide, a potential therapeutic agent in HTLV-1 associated myelopathy Retrovirology. 11: 14. DOI: 10.1186/1742-4690-11-S1-P14  0.319
2014 Brunetto GS, Massoud R, Ohayon J, Fenton K, Cortese I, Jacobson S. Digital droplet PCR for precise quantification of human T-lymphotropic virus 1 proviral loads Retrovirology. 11: 13. DOI: 10.1186/1742-4690-11-S1-P13  0.341
2014 Castro-Amarante MFd, Pise-Masison C, McKinnon K, Massoud R, Jacobson S, Franchini G. The contribution of monocytes/macrophages to HTLV-1 infection and persistence Retrovirology. 11: 123. DOI: 10.1186/1742-4690-11-S1-P123  0.354
2014 Massoud R, Enose-Akahata Y, Brunetto GS, Ohayon J, Fenton K, Cortese I, Waldmann TA, Jacobson S. Clinical trial of a humanized monoclonal anti-IL15Rβ (CD122), in HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP) Retrovirology. 11: 1-1. DOI: 10.1186/1742-4690-11-S1-O6  0.332
2014 Enose-Akahata Y, Massoud R, Virtanen JO, Jacobson S. Correlation of increased CXCL13 with intrathecal humoral immune responses to HTLV-1 in CSF of patients with HAM/TSP Retrovirology. 11: 1-1. DOI: 10.1186/1742-4690-11-S1-O38  0.357
2014 Anderson MR, Akahata Y, Massoud R, Ngouth N, Oh U, Jacobson S. HTLV-1 epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional proliferative suppression of Tregs Retrovirology. 11: 1-1. DOI: 10.1186/1742-4690-11-S1-O34  0.382
2014 Sato T, Ando H, Tomaru U, Yoshida M, Utsunomiya A, Yamauchi J, Araya N, Yagishita N, Coler-Reilly A, Jacobson S, Yamano Y. Virus-induced CXCL10-CXCR3 positive feedback loop via astrocytes is critical for maintaining chronic inflammatory lesions in HAM/TSP Retrovirology. 11: 1-1. DOI: 10.1186/1742-4690-11-S1-O25  0.412
2014 Pise-Masison C, Castro-Amarante MFd, Buchmann C, Enoso-Akahata Y, Fenezia C, Edwards D, Alcantara LCJ, Bialuk I, Jacobson S, Galvao-Castro B, Gessain A, Franchini G. Both orf-I isoforms, p12 and p8, are required for efficient HTLV-1 infection and persistence Retrovirology. 11: 1-1. DOI: 10.1186/1742-4690-11-S1-O13  0.364
2014 Sousa ADPA, Nicholas R, Johnson K, Darko S, Price D, Douek D, Muraro P, Jacobson S. Deep sequencing of T-cell receptor repertoire reveals enrichment of highly expanded clonotypes in cerebrospinal fluid from multiple sclerosis Journal of Neuroimmunology. 275: 197-198. DOI: 10.1016/J.Jneuroim.2014.08.530  0.348
2014 Caruso B, Brunetto G, Massoud R, Leibovitch E, Jacobson S. Droplet digital PCR for the precise quantification of HTLV-1 Journal of Neuroimmunology. 275: 76. DOI: 10.1016/J.Jneuroim.2014.08.201  0.329
2013 Sato T, Coler-Reilly A, Utsunomiya A, Araya N, Yagishita N, Ando H, Yamauchi J, Inoue E, Ueno T, Hasegawa Y, Nishioka K, Nakajima T, Jacobson S, Izumo S, Yamano Y. CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis. Plos Neglected Tropical Diseases. 7: e2479. PMID 24130912 DOI: 10.1371/Journal.Pntd.0002479  0.39
2013 Grassi MF, Olavarria VN, Kruschewsky Rde A, Yamano Y, Jacobson S, Taylor GP, Martin F, Galvão-Castro B. Utility of HTLV proviral load quantification in diagnosis of HTLV-1-associated myelopathy requires international standardization. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 58: 584-6. PMID 24095029 DOI: 10.1016/J.Jcv.2013.09.003  0.384
2013 Ando H, Sato T, Tomaru U, Yoshida M, Utsunomiya A, Yamauchi J, Araya N, Yagishita N, Coler-Reilly A, Shimizu Y, Yudoh K, Hasegawa Y, Nishioka K, Nakajima T, Jacobson S, et al. Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy. Brain : a Journal of Neurology. 136: 2876-87. PMID 23892452 DOI: 10.1093/Brain/Awt183  0.477
2013 Enose-Akahata Y, Abrams A, Massoud R, Bialuk I, Johnson KR, Green PL, Maloney EM, Jacobson S. Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals. Retrovirology. 10: 19. PMID 23405908 DOI: 10.1186/1742-4690-10-19  0.425
2013 Harberts E, Datta D, Chen S, Wohler JE, Oh U, Jacobson S. Translocator protein 18 kDa (TSPO) expression in multiple sclerosis patients. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 51-7. PMID 22956240 DOI: 10.1007/S11481-012-9397-5  0.355
2012 Enose-Akahata Y, Matsuura E, Tanaka Y, Oh U, Jacobson S. Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease. Retrovirology. 9: 16. PMID 22335964 DOI: 10.1186/1742-4690-9-16  0.446
2012 Enose-Akahata Y, Abrams A, Johnson KR, Maloney EM, Jacobson S. Quantitative differences in HTLV-I antibody responses: classification and relative risk assessment for asymptomatic carriers and ATL and HAM/TSP patients from Jamaica. Blood. 119: 2829-36. PMID 22318200 DOI: 10.1182/Blood-2011-11-390807  0.373
2011 Araya N, Sato T, Yagishita N, Ando H, Utsunomiya A, Jacobson S, Yamano Y. Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease. Viruses. 3: 1532-48. PMID 21994794 DOI: 10.3390/V3091532  0.436
2011 de Moraes JC, Toscano CM, de Barros EN, Kemp B, Lievano F, Jacobson S, Afonso AM, Strebel PM, Cairns KL. Etiologies of rash and fever illnesses in Campinas, Brazil. The Journal of Infectious Diseases. 204: S627-36. PMID 21954258 DOI: 10.1093/Infdis/Jir490  0.318
2011 Harberts E, Yao K, Wohler JE, Maric D, Ohayon J, Henkin R, Jacobson S. Human herpesvirus-6 entry into the central nervous system through the olfactory pathway. Proceedings of the National Academy of Sciences of the United States of America. 108: 13734-9. PMID 21825120 DOI: 10.1073/Pnas.1105143108  0.355
2011 Rende F, Cavallari I, Corradin A, Silic-Benussi M, Toulza F, Toffolo GM, Tanaka Y, Jacobson S, Taylor GP, D'Agostino DM, Bangham CRM, Ciminale V. Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs. Blood. 117: 4855-4859. PMID 21398577 DOI: 10.1182/Blood-2010-11-316463  0.327
2011 Ju W, Zhang M, Jiang JK, Thomas CJ, Oh U, Bryant BR, Chen J, Sato N, Tagaya Y, Morris JC, Janik JE, Jacobson S, Waldmann TA. CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP. Blood. 117: 1938-46. PMID 21106989 DOI: 10.1182/Blood-2010-09-305425  0.329
2011 Oh U, Fujita M, Ikonomidou VN, Evangelou IE, Matsuura E, Harberts E, Fujimura Y, Richert ND, Ohayon J, Pike VW, Zhang Y, Zoghbi SS, Innis RB, Jacobson S. Translocator protein PET imaging for glial activation in multiple sclerosis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 354-61. PMID 20872081 DOI: 10.1007/S11481-010-9243-6  0.319
2011 Yamano Y, Sato T, Araya N, Yagishita N, Shimizu Y, Ando H, Utsunomiya A, Izumo S, Jacobson S, Suzuki N. Clinical subtype of HAM/TSP based on clinical course and laboratory findings Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A42  0.345
2011 Akahata Y, Abrams A, Maloney E, McCormick M, Jacobson S. Using a sensitive luciferase immunoprecipitation system (LIPS) to detect HTLV-I/II seroindeterminates in Jamaica. Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A249  0.378
2011 Rende F, Cavallari I, Corradin A, Silic-Benussi M, Toulza F, Toffolo GM, Tanaka Y, Jacobson S, Taylor GP, D'Agostino DM, Bangham CRM, Ciminale V. Kinetics and intracellular compartmentalization of HTLV-1 gene expression Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A204  0.326
2011 Alcantara LC, Bialuk I, Castro-Amarante MFd, Buchmann C, Chevalier S, Fukumoto R, Andresen V, Pise-Masison C, Jacobson S, Galvao-Castro B, Gessain A, Franchini G. The reverse genetics of HTLV-1 infected patients Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A193  0.35
2011 McCormick M, Oh U, Datta D, Turner R, Bobb K, Monie D, Sliskovic DR, Zhang J, Meshulam J, Jacobson S. NFkB activation promotes immune activation in HTLV-I-associated myelopathy / tropical spastic paraparesis Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A117  0.304
2011 Akahata Y, Abrams A, Goedert J, Maloney E, Jacobson S. Quantitative differences in antibody responses between normal donors HAM/TSP patients, asymptomatic carriers, and ATL patients from Jamaica: can they be used to estimate risk of disease? Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A110  0.358
2011 Araya N, Sato T, Utsunomiya A, Ando H, Yagishita N, Kannagi M, Nakamura T, Tanaka Y, Jacobson S, Yamano Y. The plasticity of HTLV-1 infected CD4+CD25+CCR4+ T-cells through HTLV-1 tax in HAM/TSP Retrovirology. 8: 1-1. DOI: 10.1186/1742-4690-8-S1-A104  0.43
2010 Yao K, Crawford JR, Komaroff AL, Ablashi DV, Jacobson S. Review part 2: Human herpesvirus-6 in central nervous system diseases Journal of Medical Virology. 82: 1669-1678. PMID 20827763 DOI: 10.1002/Jmv.21861  0.328
2010 Yao K, Graham J, Akahata Y, Oh U, Jacobson S. Mechanism of neuroinflammation: enhanced cytotoxicity and IL-17 production via CD46 binding. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 469-78. PMID 20661655 DOI: 10.1007/S11481-010-9232-9  0.367
2010 Soldan SS, Jacobson S. Viral infections of the central nervous system: pathogenesis to therapeutics. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 267-70. PMID 20658202 DOI: 10.1007/S11481-010-9231-X  0.673
2010 Matsuura E, Yamano Y, Jacobson S. Neuroimmunity of HTLV-I Infection Journal of Neuroimmune Pharmacology. 5: 310-325. PMID 20437106 DOI: 10.1007/S11481-010-9216-9  0.473
2010 Gordon SN, Weissman AR, Cecchinato V, Fenizia C, Ma ZM, Lee TH, Zaffiri L, Andresen V, Parks RW, Jones KS, Heraud JM, Ferrari MG, Chung HK, Venzon D, Mahieux R, ... ... Jacobson S, et al. Preexisting infection with human T-cell lymphotropic virus type 2 neither exacerbates nor attenuates simian immunodeficiency virus SIVmac251 infection in macaques. Journal of Virology. 84: 3043-58. PMID 20071587 DOI: 10.1128/Jvi.01655-09  0.459
2010 Ju W, Zhang M, Bryant BR, Chen J, Morris JC, Janik JE, Waldmann TA, Jiang J, Thomas CJ, Jacobson S, Oh U. Abstract 2526: CP690550 inhibits interleukin-2 (IL-2), IL-9 and IL-15 mediated JAK3 activation and proliferation of T cells obtained from patients with HTLV-1-associated adult T cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) Cancer Research. 70: 2526-2526. DOI: 10.1158/1538-7445.Am10-2526  0.302
2009 Gómez-Acevedo H, Li MY, Jacobson S. Multistability in a model for CTL response to HTLV-I infection and its implications to HAM/TSP development and prevention. Bulletin of Mathematical Biology. 72: 681-96. PMID 20041353 DOI: 10.1007/s11538-009-9465-z  0.337
2009 Enose-Akahata Y, Matsuura E, Oh U, Jacobson S. High expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic disease. Plos Pathogens. 5: e1000682. PMID 19997502 DOI: 10.1371/Journal.Ppat.1000682  0.397
2009 Yamano Y, Araya N, Sato T, Utsunomiya A, Azakami K, Hasegawa D, Izumi T, Fujita H, Aratani S, Yagishita N, Fujii R, Nishioka K, Jacobson S, Nakajima T. Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder. Plos One. 4: e6517. PMID 19654865 DOI: 10.1371/Journal.Pone.0006517  0.434
2009 Yao K, Hoest C, Rashti F, Schott TC, Jacobson S. Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT-lipid-PFA on human herpesvirus-6B infected cells. Journal of Clinical Virology. 46: 10-14. PMID 19524486 DOI: 10.1016/J.Jcv.2009.05.014  0.37
2009 Oh U, Blevins G, Griffith C, Richert N, Maric D, Lee CR, McFarland H, Jacobson S. Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis. Archives of Neurology. 66: 471-9. PMID 19364932 DOI: 10.1001/Archneurol.2009.16  0.344
2009 Yao K, Honarmand S, Espinosa A, Akhyani N, Glaser C, Jacobson S. Detection of human herpesvirus-6 in cerebrospinal fluid of patients with encephalitis. Annals of Neurology. 65: 257-67. PMID 19334059 DOI: 10.1002/Ana.21611  0.459
2008 Burbelo PD, Meoli E, Leahy HP, Graham J, Yao K, Oh U, Janik JE, Mahieux R, Kashanchi F, Iadarola MJ, Jacobson S. Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology. 5: 96. PMID 18937847 DOI: 10.1186/1742-4690-5-96  0.311
2008 Theodore WH, Epstein L, Gaillard WD, Shinnar S, Wainwright MS, Jacobson S. Human herpes virus 6B: a possible role in epilepsy? Epilepsia. 49: 1828-37. PMID 18627418 DOI: 10.1111/J.1528-1167.2008.01699.X  0.365
2008 Enose-Akahata Y, Oh U, Grant C, Jacobson S. Retrovirally induced CTL degranulation mediated by IL-15 expression and infection of mononuclear phagocytes in patients with HTLV-I-associated neurologic disease. Blood. 112: 2400-10. PMID 18509087 DOI: 10.1182/Blood-2008-02-138529  0.416
2008 Yao K, Gagnon S, Akhyani N, Williams E, Fotheringham J, Frohman E, Stuve O, Monson NL, Racke MK, Jacobson S. Reactivation of human herpesvirus-6 in natalizumab treated multiple sclerosis patients. Plos One. 3. PMID 18446218 DOI: 10.1371/Journal.Pone.0002028  0.473
2008 Grant C, Oh U, Yao K, Yamano Y, Jacobson S. Dysregulation of TGF-beta signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease. Blood. 111: 5601-9. PMID 18326816 DOI: 10.1182/Blood-2007-11-123430  0.4
2008 Fotheringham J, Williams EL, Akhyani N, Jacobson S. Human herpesvirus 6 (HHV-6) induces dysregulation of glutamate uptake and transporter expression in astrocytes. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 3: 105-16. PMID 18247129 DOI: 10.1007/S11481-007-9084-0  0.359
2007 Hammarstedt M, Ahlqvist J, Jacobson S, Garoff H, Fogdell-Hahn A. Purification of infectious human herpesvirus 6A virions and association of host cell proteins. Virology Journal. 4: 101-101. PMID 17949490 DOI: 10.1186/1743-422X-4-101  0.354
2007 Ratner L, Grant C, Zimmerman B, Fritz J, Weil G, Denes A, Suresh R, Campbell N, Jacobson S, Lairmore M. Effect of treatment of Strongyloides infection on HTLV-1 expression in a patient with adult T-cell leukemia. American Journal of Hematology. 82: 929-31. PMID 17617788 DOI: 10.1002/Ajh.20929  0.331
2007 Fotheringham J, Donati D, Akhyani N, Fogdell-Hahn A, Vortmeyer A, Heiss JD, Williams E, Weinstein S, Bruce DA, Gaillard WD, Sato S, Theodore WH, Jacobson S. Association of human herpesvirus-6B with mesial temporal lobe epilepsy. Plos Medicine. 4: e180. PMID 17535102 DOI: 10.1371/Journal.Pmed.0040180  0.333
2007 Puccioni-Sohler M, Yamano Y, Rios M, Carvalho SM, Vasconcelos CC, Papais-Alvarenga R, Jacobson S. Differentiation of HAM/TSP from patients with multiple sclerosis infected with HTLV-I. Neurology. 68: 206-13. PMID 17224575 DOI: 10.1212/01.wnl.0000251300.24540.c4  0.372
2007 Fotheringham J, Akhyani N, Vortmeyer A, Donati D, Williams E, Oh U, Bishop M, Barrett J, Gea-Banacloche J, Jacobson S. Detection of active human herpesvirus-6 infection in the brain: correlation with polymerase chain reaction detection in cerebrospinal fluid. The Journal of Infectious Diseases. 195: 450-4. PMID 17205485 DOI: 10.1086/510757  0.361
2007 Takenouchi N, Jones KS, Lisinski I, Fugo K, Yao K, Cushman SW, Ruscetti FW, Jacobson S. GLUT1 is not the primary binding receptor but is associated with cell-to-cell transmission of human T-cell leukemia virus type 1. Journal of Virology. 81: 1506-10. PMID 17108050 DOI: 10.1128/Jvi.01522-06  0.413
2006 Griffith C, Bagnato F, Gupta S, Calabrese A, Oh U, Chiu A, Ohayon JM, McAuliffe MJ, Tasciyan TA, Jacobson S. Brain volume measurements in patients with human T-cell lymphotropic virus-1-associated tropical spastic paraparesis. Journal of Neurovirology. 12: 349-55. PMID 17065127 DOI: 10.1080/13550280600941665  0.373
2006 Ahlqvist J, Donati D, Martinelli E, Akhyani N, Hou J, Major EO, Jacobson S, Fogdell-Hahn A. Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A in astrocytes and in T-cells. Journal of Medical Virology. 78: 1542-53. PMID 17063514 DOI: 10.1002/Jmv.20737  0.372
2006 Akhyani N, Fotheringham J, Yao K, Rashti F, Jacobson S. Efficacy of antiviral compounds in human herpesvirus-6-infected glial cells Journal of Neurovirology. 12: 284-293. PMID 16966219 DOI: 10.1080/13550280600880772  0.382
2006 Jones KS, Fugo K, Petrow-Sadowski C, Huang Y, Bertolette DC, Lisinski I, Cushman SW, Jacobson S, Ruscetti FW. Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 use different receptor complexes to enter T cells. Journal of Virology. 80: 8291-302. PMID 16912281 DOI: 10.1128/Jvi.00389-06  0.393
2006 Maloney EM, Yamano Y, Vanveldhuisen PC, Sawada T, Kim N, Cranston B, Hanchard B, Jacobson S, Hisada M. Natural history of viral markers in children infected with human T lymphotropic virus type I in Jamaica. The Journal of Infectious Diseases. 194: 552-60. PMID 16897651 DOI: 10.1086/506365  0.356
2006 Oh U, Grant C, Griffith C, Fugo K, Takenouchi N, Jacobson S. Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection. The Journal of Infectious Diseases. 193: 1557-66. PMID 16652285 DOI: 10.1086/503874  0.462
2006 Grant C, Oh U, Fugo K, Takenouchi N, Griffith C, Yao K, Newhook TE, Ratner L, Jacobson S. Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways. Plos Pathogens. 2: e33. PMID 16652169 DOI: 10.1371/Journal.Ppat.0020033  0.391
2006 Kazanji M, Heraud J, Merien F, Pique C, Gessain A, Jacobson S. Chimeric peptide vaccine composed of B- and T-cell epitopes of human T-cell leukemia virus type 1 induces humoral and cellular immune responses and reduces the proviral load in immunized squirrel monkeys (Saimiri sciureus). Journal of General Virology. 87: 1331-1337. PMID 16603536 DOI: 10.1099/Vir.0.81582-0  0.412
2006 Sibon D, Gabet A, Zandecki M, Pinatel C, Thête J, Delfau-Larue M, Rabaaoui S, Gessain A, Gout O, Jacobson S, Mortreux F, Wattel E. HTLV-1 propels untransformed CD4 lymphocytes into the cell cycle while protecting CD8 cells from death. Journal of Clinical Investigation. 116: 974-983. PMID 16585963 DOI: 10.1172/Jci27198  0.375
2006 Azimi N, Jacobson S, Tanaka Y, Corey L, Groh V, Spies T. Immunostimulation by induced expression of NKG2D and its MIC ligands in HTLV-1-associated neurologic disease. Immunogenetics. 58: 252-8. PMID 16568261 DOI: 10.1007/S00251-006-0082-9  0.454
2006 Yao K, Mandel M, Akyani N, Maynard K, Sengamalay N, Fotheringham J, Ghedin E, Kashanchi F, Jacobson S. Differential HHV-6A gene expression in T cells and primary human astrocytes based on multi-virus array analysis. Glia. 53: 789-98. PMID 16541415 DOI: 10.1002/Glia.20333  0.466
2006 Yao K, Hisada M, Maloney E, Yamano Y, Hanchard B, Wilks R, Rios M, Jacobson S. Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I. The Journal of Infectious Diseases. 193: 427-37. PMID 16388491 DOI: 10.1086/499273  0.335
2006 Jacobson S. The emerging role of HHV-6 in neurologic disease: lesson from multiple sclerosis and epilepsy Retrovirology. 3: 1-1. DOI: 10.1186/1742-4690-3-S1-S64  0.428
2006 Ahlqvist J, Donati D, Martinelli E, Akhyani N, Hou J, Major EO, Jacobson S, Fogdell-Hahn A. 4: Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A (HHV-6A) in astrocytes and in T-cells Journal of Clinical Virology. 37. DOI: 10.1016/S1386-6532(06)70023-3  0.366
2006 Soldan SS, Goodman AD, Jacobson S. HHV-6 and the Central Nervous System Perspectives in Medical Virology. 12: 213-223. DOI: 10.1016/S0168-7069(06)12016-9  0.689
2005 Bagnato F, Butman JA, Mora CA, Gupta S, Yamano Y, Tasciyan TA, Solomon JM, Santos WJ, Stone RD, McFarland HF, Jacobson S. Conventional magnetic resonance imaging features in patients with tropical spastic paraparesis. Journal of Neurovirology. 11: 525-34. PMID 16338746 DOI: 10.1080/13550280500385039  0.316
2005 Ahlqvist J, Fotheringham J, Akhyani N, Yao K, Fogdell-Hahn A, Jacobson S. Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes. Journal of Neurovirology. 11: 384-394. PMID 16162481 DOI: 10.1080/13550280591002379  0.379
2005 Cassiani-Ingoni R, Greenstone HL, Donati D, Fogdell-Hahn A, Martinelli E, Refai D, Martin R, Berger EA, Jacobson S. CD46 on glial cells can function as a receptor for viral glycoprotein‐mediated cell–cell fusion Glia. 52: 252-258. PMID 15920733 DOI: 10.1002/Glia.20219  0.422
2005 Semmes OJ, Cazares LH, Ward MD, Qi L, Moody M, Maloney E, Morris J, Trosset MW, Hisada M, Gygi S, Jacobson S. Discrete serum protein signatures discriminate between human retrovirus-associated hematologic and neurologic disease. Leukemia. 19: 1229-38. PMID 15889159 DOI: 10.1038/Sj.Leu.2403781  0.405
2005 Yamano Y, Takenouchi N, Li H, Tomaru U, Yao K, Grant CW, Maric DA, Jacobson S. Virus-induced dysfunction of CD4 + CD25 + T cells in patients with HTLV-I–associated neuroimmunological disease Journal of Clinical Investigation. 115: 1361-1368. PMID 15864353 DOI: 10.1172/Jci23913  0.388
2005 Fogdell-Hahn A, Soldan SS, Shue S, Akhyani N, Refai H, Ahlqvist J, Jacobson S. Co-purification of soluble membrane cofactor protein (CD46) and human herpesvirus 6 variant A genome in serum from multiple sclerosis patients Virus Research. 110: 57-63. PMID 15845255 DOI: 10.1016/j.virusres.2005.01.005  0.645
2005 Murphy E, Jacobson S, Franchini G, Taylor GP, Hanchard B, Morgan O, Lairmore M. International Retrovirology Association brings together scientists and clinicians to bridge discoveries about human T-lymphotropic viruses from the laboratory to clinical trials Retrovirology. 2. PMID 15796774 DOI: 10.1186/1742-4690-2-22  0.333
2005 Oh U, Yamano Y, Mora CA, Ohayon J, Bagnato F, Butman JA, Dambrosia J, Leist TP, McFarland H, Jacobson S. Interferon-beta1a therapy in human T-lymphotropic virus type I-associated neurologic disease. Annals of Neurology. 57: 526-34. PMID 15786444 DOI: 10.1002/Ana.20429  0.438
2005 Allegretta M, Ardell SK, Sullivan LM, Jacobson S, Mortreux F, Wattel E, Albertini RJ. HPRT mutations, TCR gene rearrangements, and HTLV-1 integration sites define in vivo T-cell clonal lineages. Environmental and Molecular Mutagenesis. 45: 326-337. PMID 15744741 DOI: 10.1002/Em.20120  0.337
2005 Puccioni-Sohler M, Papais-Alvarenga R, de Souza PM, de França SC, Gonçalves RR, Jacobson S. Parkinsonism in the course of HTLV-I-associated myelopathy. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 613-5. PMID 15726580 DOI: 10.1002/Mds.20402  0.41
2005 Porto AF, Santos SB, Muniz AL, Basílio V, Rodrigues W, Neva FA, Dutra WO, Gollob KJ, Jacobson S, Carvalho EM. Helminthic infection down-regulates type 1 immune responses in human T cell lymphotropic virus type 1 (HTLV-1) carriers and is more prevalent in HTLV-1 carriers than in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis Journal of Infectious Diseases. 191: 612-618. PMID 15655786 DOI: 10.1086/427560  0.437
2005 Jacobson S, Lipkin WI. Reviews in NeuroVirology: An introduction Journal of Neurovirology. 11: 411-411. DOI: 10.1080/13550280500406108  0.342
2004 Sundaram R, Lynch MP, Rawale S, Dakappagari N, Young D, Walker CM, Lemonnier F, Jacobson S, Kaumaya PT. Protective efficacy of multiepitope human leukocyte antigen-A*0201 restricted cytotoxic T-lymphocyte peptide construct against challenge with human T-cell lymphotropic virus type 1 Tax recombinant vaccinia virus. Journal of Acquired Immune Deficiency Syndromes (1999). 37: 1329-39. PMID 15483462 DOI: 10.1097/00126334-200411010-00001  0.421
2004 Takenouchi N, Yao K, Jacobson S. Immunopathogensis of HTLV-I associated neurologic disease: molecular, histopathologic, and immunologic approaches. Frontiers in Bioscience. 9: 2527. PMID 15353305 DOI: 10.2741/1414  0.457
2004 Monsurrò V, Wang E, Yamano Y, Migueles SA, Panelli MC, Smith K, Nagorsen D, Connors M, Jacobson S, Marincola FM. Quiescent phenotype of tumor-specific CD8+ T cells following immunization Blood. 104: 1970-1978. PMID 15187028 DOI: 10.1182/Blood-2004-02-0525  0.375
2004 Ghedin E, Pumfery A, de la Fuente C, Yao K, Miller N, Lacoste V, Quackenbush J, Jacobson S, Kashanchi F. Use of a multi-virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP-chip analysis. Retrovirology. 1: 10. PMID 15169557 DOI: 10.1186/1742-4690-1-10  0.364
2004 Yamano Y, Cohen CJ, Takenouchi N, Yao K, Tomaru U, Li H, Reiter Y, Jacobson S. Increased expression of human T lymphocyte virus type I (HTLV-I) Tax11-19 peptide-human histocompatibility leukocyte antigen A*201 complexes on CD4+ CD25+ T Cells detected by peptide-specific, major histocompatibility complex-restricted antibodies in patients with HTLV-I-associated neurologic disease. Journal of Experimental Medicine. 199: 1367-1377. PMID 15136590 DOI: 10.1084/Jem.20032042  0.435
2004 Maloney EM, Nagai M, Hisada M, Soldan SS, Goebel PB, Carrington M, Sawada T, Brennan MB, Cranston B, Hanchard B, Jacobson S. Prediagnostic human T lymphotropic virus type I provirus loads were highest in Jamaican children who developed seborrheic dermatitis and severe anemia. The Journal of Infectious Diseases. 189: 41-5. PMID 14702151 DOI: 10.1086/380567  0.679
2004 Soldan SS, Jacobson S. Infection and Multiple Sclerosis Infection and Autoimmunity, 2nd Edition. 559-582. DOI: 10.1016/B978-044451271-0.50044-2  0.674
2003 Cermelli C, Berti R, Soldan SS, Mayne M, D'ambrosia JM, Ludwin SK, Jacobson S. High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection. The Journal of Infectious Diseases. 187: 1377-87. PMID 12717618 DOI: 10.1086/368166  0.652
2003 Cohen CJ, Sarig O, Yamano Y, Tomaru U, Jacobson S, Reiter Y. Direct phenotypic analysis of human MHC class I antigen presentation: Visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodies Journal of Immunology. 170: 4349-4361. PMID 12682272 DOI: 10.4049/Jimmunol.170.8.4349  0.367
2003 Tomaru U, Yamano Y, Nagai M, Maric D, Kaumaya PTP, Biddison W, Jacobson S. Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide-HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections. Nature Medicine. 9: 469-475. PMID 12652294 DOI: 10.1038/Nm845  0.433
2003 Puccioni-Sohler M, Chimelli L, Merçon M, Gonçalves RR, Pimenta G, Bianco C, Rios M, Jacobson S. Pathological and virological assessment of acute HTLV-I-associated myelopathy complicated with encephalopathy and systemic inflammation. Journal of the Neurological Sciences. 207: 87-93. PMID 12614936 DOI: 10.1016/S0022-510X(02)00413-6  0.408
2003 Muraro PA, Wandinger KP, Bielekova B, Gran B, Marques A, Utz U, McFarland HF, Jacobson S, Martin R. Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. Brain : a Journal of Neurology. 126: 20-31. PMID 12477694 DOI: 10.1093/Brain/Awg021  0.309
2002 Jacobson S. Immunopathogenesis of human T cell lymphotropic virus type I-associated neurologic disease. The Journal of Infectious Diseases. S187-92. PMID 12424696 DOI: 10.1086/344269  0.367
2002 Fogdell-Hahn A, Soldan SS, Jacobson S. Association of chronic progressive neurological disease and ubiquitous viral agents: Lessons from human herpesvirus 6 and multiple sclerosis Molecular Psychiatry. 7. PMID 12142941  0.651
2002 Berti R, Brennan MB, Soldan SS, Ohayon JM, Casareto L, McFarland HF, Jacobson S. Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression. Journal of Neurovirology. 8: 250-6. PMID 12053279 DOI: 10.1080/13550280290049615-1  0.659
2002 Kubota R, Soldan SS, Martin R, Jacobson S. Selected cytotoxic T lymphocytes with high specificity for HTLV-I in cerebrospinal fluid from a HAM/TSP patient. Journal of Neurovirology. 8: 53-7. PMID 11847592 DOI: 10.1080/135502802317247811  0.697
2002 Grant C, Barmak K, Alefantis T, Yao J, Jacobson S, Wigdahl B. Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation. Journal of Cellular Physiology. 190: 133-59. PMID 11807819 DOI: 10.1002/Jcp.10053  0.475
2002 Yamano Y, Nagai M, Brennan M, Mora CA, Soldan SS, Tomaru U, Takenouchi N, Izumo S, Osame M, Jacobson S. Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP). Blood. 99: 88-94. PMID 11756157 DOI: 10.1182/Blood.V99.1.88  0.691
2001 Nagai M, Yamano Y, Brennan MB, Mora CA, Jacobson S. Increased HTLV-I proviral load and preferential expansion of HTLV-I Tax-specific CD8+ T cells in cerebrospinal fluid from patients with HAM/TSP. Annals of Neurology. 50: 807-812. PMID 11761481 DOI: 10.1002/Ana.10065  0.449
2001 Azimi N, Nagai M, Jacobson S, Waldmann TA. IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients. Proceedings of the National Academy of Sciences of the United States of America. 98: 14559-64. PMID 11717409 DOI: 10.1073/Pnas.251540598  0.384
2001 Mayne M, Cheadle C, Soldan SS, Cermelli C, Yamano Y, Akhyani N, Nagel JE, Taub DD, Becker KG, Jacobson S. Gene expression profile of herpesvirus-infected T cells obtained using immunomicroarrays: Induction of proinflammatory mechanisms Journal of Virology. 75: 11641-11650. PMID 11689646 DOI: 10.1128/Jvi.75.23.11641-11650.2001  0.674
2001 Soldan SS, Fogdell-Hahn A, Brennan MB, Mittleman BB, Ballerini C, Massacesi L, Seya T, McFarland HF, Jacobson S. Elevated serum and cerebrospinal fluid levels of soluble human herpesvirus type 6 cellular receptor, membrane cofactor protein, in patients with multiple sclerosis. Annals of Neurology. 50: 486-93. PMID 11603380 DOI: 10.1002/Ana.1135  0.668
2001 Nagai M, Brennan MB, Sakai JA, Mora CA, Jacobson S. CD8(+) T cells are an in vivo reservoir for human T-cell lymphotropic virus type I. Blood. 98: 1858-61. PMID 11535522 DOI: 10.1182/Blood.V98.6.1858  0.424
2001 Sakai JA, Nagai M, Brennan MB, Mora CA, Jacobson S. In vitro spontaneous lymphoproliferation in patients with human T-cell lymphotropic virus type I-associated neurologic disease: predominant expansion of CD8+ T cells. Blood. 98: 1506-11. PMID 11520801 DOI: 10.1182/Blood.V98.5.1506  0.416
2001 Levin MC, Rosenblum MK, Fox CH, Jacobson S. Localization of retrovirus in the central nervous system of a patient co-infected with HTLV-1 and HIV with HAM/TSP and HIV-associated dementia. Journal of Neurovirology. 7: 61-5. PMID 11519484 DOI: 10.1080/135502801300069719  0.314
2001 Soldan SS, Jacobson S. Role of viruses in etiology and pathogenesis of multiple sclerosis Advances in Virus Research. 56: 517-555. PMID 11450311 DOI: 10.1016/S0065-3527(01)56037-6  0.687
2001 Nagai M, Jacobson S. Immunopathogenesis of human T cell lymphotropic virus type I-associated myelopathy. Current Opinion in Neurology. 14: 381-386. PMID 11371764 DOI: 10.1097/00019052-200106000-00019  0.476
2001 Jacobson S, Cross A. Association of Chlamydia pneumoniae and multiple sclerosis: Stage two? Neurology. 56: 1128-1129. PMID 11342674 DOI: 10.1212/Wnl.56.9.1128  0.352
2001 Cermelli C, Jacobson S. Viruses and multiple sclerosis. Viral Immunology. 13: 255-67. PMID 11016591 DOI: 10.1089/08828240050144590  0.324
2000 Nagai M, Kubota R, Greten TF, Schneck JP, Leist TP, Jacobson S. Increased activated human T cell lymphotropic virus type I (HTLV-I) Tax11-19-specific memory and effector CD8+ cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis: correlation with HTLV-I provirus load. The Journal of Infectious Diseases. 183: 197-205. PMID 11120926 DOI: 10.1086/317932  0.379
2000 Albertini RJ, Ardell SK, Judice SA, Jacobson S, Allegretta M. Hypoxanthine-guanine phosphoribosyltransferase reporter gene mutation for analysis of in vivo clonal amplification in patients with HTLV type 1-associated Myelopathy/Tropical spastic paraparesis. Aids Research and Human Retroviruses. 16: 1747-1752. PMID 11080821 DOI: 10.1089/08892220050193254  0.38
2000 Azimi N, Mariner J, Jacobson S, Waldmann TA. How does interleukin 15 contribute to the pathogenesis of HTLV type 1-associated myelopathy/tropical spastic paraparesis? Aids Research and Human Retroviruses. 16: 1717-22. PMID 11080816 DOI: 10.1089/08892220050193209  0.346
2000 Kubota R, Nagai M, Kawanishi T, Osame M, Jacobson S. Increased HTLV type 1 tax-specific CD8+ cells in HTLV type 1-associated myelopathy/tropical spastic paraparesis: Correlation with HTLV type 1 proviral load Aids Research and Human Retroviruses. 16: 1705-1709. PMID 11080814 DOI: 10.1089/08892220050193182  0.417
2000 Akhyani N, Berti R, Brennan MB, Soldan SS, Eaton JM, McFarland HF, Jacobson S. Tissue distribution and variant characterization of human herpesvirus (HHV)-6: increased prevalence of HHV-6A in patients with multiple sclerosis. The Journal of Infectious Diseases. 182: 1321-5. PMID 11023456 DOI: 10.1086/315893  0.681
2000 Kubota R, Soldan SS, Martin R, Jacobson S. An altered peptide ligand antagonizes antigen-specific T cells of patients with human T lymphotropic virus type I-associated neurological disease Journal of Immunology. 164: 5192-5198. PMID 10799878 DOI: 10.4049/Jimmunol.164.10.5192  0.7
2000 Soldan SS, Leist TP, Juhng KN, McFarland HF, Jacobson S. Increased lymphoproliferative response to human herpesvirus type 6A variant in multiple sclerosis patients. Annals of Neurology. 47: 306-13. PMID 10716249 DOI: 10.1002/1531-8249(200003)47:3<306::Aid-Ana5>3.0.Co;2-A  0.676
2000 Waziri A, Soldan SS, Graf MD, Nagle J, Jacobson S. Characterization and sequencing of prototypic human T-lymphotropic virus type 1 (HTLV-1) from an HTLV-1/2 seroindeterminate patient. Journal of Virology. 74: 2178-85. PMID 10666247 DOI: 10.1128/Jvi.74.5.2178-2185.2000  0.684
2000 Kubota R, Kawanishi T, Matsubara H, Manns A, Jacobson S. HTLV-I specific IFN-γ+ CD8+ lymphocytes correlate with the proviral load in peripheral blood of infected individuals Journal of Neuroimmunology. 102: 208-215. PMID 10636490 DOI: 10.1016/S0165-5728(99)00175-7  0.41
1999 Soldan SS, Graf MD, Waziri A, Flerlage AN, Robinson SM, Kawanishi T, Leist TP, Lehky TJ, Levin MC, Jacobson S. HTLV-I/II seroindeterminate Western blot reactivity in a cohort of patients with neurological disease. The Journal of Infectious Diseases. 180: 685-94. PMID 10438355 DOI: 10.1086/314923  0.679
1999 Calabresi PA, Martin R, Jacobson S. Chemokines in chronic progressive neurological diseases: HTLV-1 associated myelopathy and multiple sclerosis. Journal of Neurovirology. 5: 102-8. PMID 10190696 DOI: 10.3109/13550289909029751  0.41
1999 Berti R, Jacobson S. Role of Viral Infection in the Aetiology of Multiple Sclerosis Cns Drugs. 12: 1-7. DOI: 10.2165/00023210-199912010-00001  0.419
1999 Leist TP, Otero-Quintero S, Soldan SS, Jacobson S. Interferon beta induces interferon regulatory factor-2 and inhibits T cell proliferation during infection with HTLV-I Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A50. DOI: 10.1097/00042560-199904010-00183  0.654
1999 Nagai M, Kubota R, Schneck JP, Jacobson S. Phenotypic analysis of HTLV-I Tax11-19-specific CD8+ cells Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A48. DOI: 10.1097/00042560-199904010-00177  0.308
1999 Kubota R, Soldan SS, Martin R, Jacobson S. AN ALTERED PEPTIDE LIGAND ANTAGONIZES ANTIGEN-SPECIFIC CD8+ CTL IN PERIPHERAL BLOOD OF HAM/TSP PATIENTS Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A46. DOI: 10.1097/00042560-199904010-00168  0.631
1999 Waziri A, Graf M, Soldan SS, Jacobson S. Characterization and Sequencing of a Full-Length Form of HTLV-I from an HTLV-I/II Seroindeterminate Individual Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A24. DOI: 10.1097/00042560-199904010-00084  0.596
1999 Soldan SS, Phillips TM, Jacobson S. Multiple Cytokine and Chemokine Analysis from Serum and CSF of HAM/TSP Patients and Asymptomatic Carriers by Recycling Immunoaffinity Chromatography. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A21. DOI: 10.1097/00042560-199904010-00076  0.638
1999 Jacobson S, Greten TF, Kubota R, Schenck J. Detection of HTLV-I tax Specific T Cells by Soluble Divalent HLA-Ig Fusion Proteins in PBL and CSF of HAM/TSP patients. Journal of Acquired Immune Deficiency Syndromes. 20. DOI: 10.1097/00042560-199904010-00058  0.366
1999 Azimi N, Tagaya Y, Jacobson S, Waldmann T. Human T-Cell Lymphotropic Virus-I Tax Protein Transactivates Il-2 And Il-15 Gene Transcription: Pathogenic Implications And Rationale For Immunotherapy. Journal of Acquired Immune Deficiency Syndromes. 20. DOI: 10.1097/00042560-199904010-00018  0.314
1998 Lehky TJ, Levin MC, Kubota R, Bamford RN, Flerlage AN, Soldan SS, Leist TP, Xavier A, White JD, Brown M, Fleisher TA, Top LE, Light S, McFarland HF, Waldmann TA, ... Jacobson S, et al. Reduction in HTLV-I proviral load and spontaneous lymphoproliferation in HTLV-I-associated myelopathy/tropical spastic paraparesis patients treated with humanized anti-Tac. Annals of Neurology. 44: 942-7. PMID 9851439 DOI: 10.1002/Ana.410440613  0.708
1998 Jacobson S. Association of human herpesvirus-6 and multiple sclerosis: Here we go again? Journal of Neurovirology. 4: 471-473. PMID 9839644 DOI: 10.3109/13550289809113491  0.376
1998 Levin MC, Krichavsky M, Berk J, Foley S, Rosenfeld M, Dalmau J, Chang G, Posner JB, Jacobson S. Neuronal molecular mimicry in immune-mediated neurologic disease. Annals of Neurology. 44: 87-98. PMID 9667596 DOI: 10.1002/Ana.410440115  0.379
1998 Greten TF, Slansky JE, Kubota R, Soldan SS, Jaffee EM, Leist TP, Pardoll DM, Jacobson S, Schneck JP. Direct visualization of antigen-specific T cells: HTLV-1 TAX11-19- specific CD8+ T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients Proceedings of the National Academy of Sciences of the United States of America. 95: 7568-7573. PMID 9636190 DOI: 10.1073/Pnas.95.13.7568  0.685
1998 Drew PD, Gado AM, Canning RD, Nagle JW, Dehejia AM, Polymeropoulos MH, Biddison WE, Jacobson S, Becker KG. C2H2-546: a zinc finger protein differentially expressed in HTLV-1 infected T cells. Journal of Neurovirology. 3: 455-9. PMID 9475118 DOI: 10.3109/13550289709031192  0.321
1998 Jacobson S, Soldan SS, Berti R. Reply to “HHV-6 and multiple sclerosis” Nature Medicine. 4: 538-538. DOI: 10.1038/Nm0598-538  0.624
1997 Soldan SS, Berti R, Salem N, Secchiero P, Flamand L, Calabresi PA, Brennan MB, Maloni HW, McFarland HF, Lin HC, Patnaik M, Jacobson S. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nature Medicine. 3: 1394-7. PMID 9396611 DOI: 10.1038/Nm1297-1394  0.716
1997 Méndez E, Kawanishi T, Clemens K, Siomi H, Soldan SS, Calabresi P, Brady J, Jacobson S. Astrocyte-specific expression of human T-cell lymphotropic virus type 1 (HTLV-1) Tax: Induction of tumor necrosis factor alpha and susceptibility to lysis by CD8+ HTLV-1-specific cytotoxic T cells Journal of Virology. 71: 9143-9149. PMID 9371571 DOI: 10.1128/Jvi.71.12.9143-9149.1997  0.711
1997 Levin MC, Jacobson S. HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP): a chronic progressive neurologic disease associated with immunologically mediated damage to the central nervous system. Journal of Neurovirology. 3: 126-138. PMID 9111175 DOI: 10.3109/13550289709015802  0.418
1997 Levin MC, Lehky TJ, Flerlage AN, Katz D, Kingma DW, Jaffe ES, Heiss JD, Patronas N, Mcfarland HF, Jacobson S. Immunologic analysis of a spinal cord-biopsy specimen from a patient with human T-cell lymphotropic virus type I-associated neurologic disease New England Journal of Medicine. 336: 839-845. PMID 9062093 DOI: 10.1056/Nejm199703203361205  0.446
1997 Levin MC, Krichavsky M, Fox RJ, Lehky T, Jacobson S, Edwards RJ, Jack NE, Bartholomew C. Extensive Latent Retroviral Infection in Bone Marrow of Patients With HTLV-I–Associated Neurologic Disease Blood. 89: 346-347. DOI: 10.1182/Blood.V89.1.346.346_346_347  0.47
1997 Walter MJ, Lehky TJ, Levin MC, Fox CH, Jacobson S. Detection of HTLV-I in peripheral blood lymphocytes from patients with chronic HTLV-I-associated myelopathy/tropical spastic paraparesis and asymptomatic carriers by PCR-in situ hybridization Journal of Biomedical Science. 4: 54-60. DOI: 10.1007/Bf02255594  0.449
1996 Lehky TJ, Flerlage N, Katz D, Houff S, Hall WH, Ishii K, Monken C, Dhib-Jalbut S, McFarland HF, Jacobson S. Human T-cell lymphotropic virus type II-associated myelopathy: Clinical and immunologic profiles Annals of Neurology. 40: 714-723. PMID 8957012 DOI: 10.1002/Ana.410400507  0.418
1996 Fox RJ, Levin MC, Jacobson S. Tumor necrosis factor alpha expression in the spinal cord of human T-cell lymphotrophic virus type I associated myelopathy/tropical spastic paraparesis patients Journal of Neurovirology. 2: 323-329. PMID 8912208 DOI: 10.3109/13550289609146896  0.357
1996 Medin JA, Tudor M, Simovitch R, Quirk JM, Jacobson S, Murray GJ, Brady RO. Correction in trans for Fabry disease: expression, secretion and uptake of alpha-galactosidase A in patient-derived cells driven by a high-titer recombinant retroviral vector. Proceedings of the National Academy of Sciences of the United States of America. 93: 7917-22. PMID 8755577 DOI: 10.1073/Pnas.93.15.7917  0.347
1996 Medin JA, Migita M, Pawliuk R, Jacobson S, Amiri M, Kluepfel-Stahl S, Brady RO, Humphries RK, Karlsson S. A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients. Blood. 87: 1754-62. PMID 8634421 DOI: 10.1182/Blood.V87.5.1754.Bloodjournal8751754  0.354
1996 Levin MC, Fox RJ, Lehky T, Walter M, Fox CH, Flerlage N, Bamford R, Jacobson S. PCR-in situ hybridization detection of human T-cell lymphotropic virus type 1 (HTLV-1) tax proviral DNA in peripheral blood lymphocytes of patients with HTLV-1-associated neurologic disease. Journal of Virology. 70: 924-933. PMID 8551632 DOI: 10.1128/Jvi.70.2.924-933.1996  0.402
1996 Utz U, Banks D, Jacobson S, Biddison WE. Analysis of the T-cell receptor repertoire of human T-cell leukemia virus type 1 (HTLV-1) Tax-specific CD8+ cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion. Journal of Virology. 70: 843-851. PMID 8551623 DOI: 10.1128/Jvi.70.2.843-851.1996  0.448
1996 Nishimura M, Jacobson S, Uchiyama T, Ohta M, Saida T. Human T Lymphotropic Virus Type I (Htlv-I)-Specific T Helper Cell Responses from Htlv-I Seronegative Patients with Chronic Myelopathy and Ms in Japan: Multiple Sclerosis Journal. 1: 200-203. DOI: 10.1177/135245859600100402  0.49
1995 Lehky TJ, Jacobson S. Induction of HLA class II in HTLV-I infected neuronal cell lines. Journal of Neurovirology. 1: 145-156. PMID 9222353 DOI: 10.3109/13550289509113961  0.422
1995 Migita M, Medin JA, Pawliuk R, Jacobson S, Nagle JW, Anderson S, Amiri M, Humphries RK, Karlsson S. Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors Proceedings of the National Academy of Sciences of the United States of America. 92: 12075-12079. PMID 8618847 DOI: 10.1073/Pnas.92.26.12075  0.362
1995 Elovaara I, Utz U, Smith S, Jacobson S. Limited T cell receptor usage by HTLV-I tax-specific, HLA class I restricted cytotoxic T lymphocytes from patients with HTLV-I associated neurological disease. Journal of Neuroimmunology. 63: 47-53. PMID 8557824 DOI: 10.1016/0165-5728(95)00129-8  0.42
1995 Lehky TJ, Fox CH, Koenig S, Levin MC, Flerlage N, Izumo S, Sato E, Raine CS, Osame M, Jacobson S. Detection of human T-lymphotropic virus type I (HTLV-I) tax RNA in the central nervous system of HTLV-I-associated myelopathy/tropical spastic paraparesis patients by in situ hybridization. Annals of Neurology. 37: 167-75. PMID 7847858 DOI: 10.1002/Ana.410370206  0.397
1995 Jacobson S. Human T lymphotropic virus, type-I myelopathy: an immunopathologically mediated chronic progressive disease of the central nervous system. Current Opinion in Neurology. 8: 179-183. DOI: 10.1097/00019052-199506000-00005  0.44
1994 Jacobson S, Utz U, Smith S, Elovaara I. Limited T cell receptor Vα and Vβ chain usage in HTLV-I specific cytotoxic T lymphocytes in HAM/TSP patients Journal of Neuroimmunology. 54: 170. DOI: 10.1016/0165-5728(94)90371-9  0.353
1994 Elovaara I, Utz U, Smith S, Lehky T, Jacobson S. Restricted TCR Vα and Vβ usage by HTLV-specific CD8+ CTL from peripheral blood of patients with HAM/TSP Journal of Neuroimmunology. 54: 157. DOI: 10.1016/0165-5728(94)90294-1  0.324
1993 Elovaara I, Koenig S, Brewah AY, Woods RM, Lehky T, Jacobson S. High human T cell lymphotropic virus type 1 (HTLV-1)-specific precursor cytotoxic T lymphocyte frequencies in patients with HTLV-1-associated neurological disease. The Journal of Experimental Medicine. 177: 1567-73. PMID 8496677 DOI: 10.1084/Jem.177.6.1567  0.427
1993 Jacobson S, Lehky T, Nishimura M, Robinson S, McFarlin DE, Dhib-Jalbut S. Isolation of HTLV-II from a patient with chronic, progressive neurological disease clinically indistinguishable from HTLV-I-associated myelopathy/tropical spastic paraparesis. Annals of Neurology. 33: 392-6. PMID 8489210 DOI: 10.1002/ANA.410330411  0.301
1993 Levine PH, Jacobson S, Elliott R, Cavallero A, Colclough G, Dorry C, Stephenson C, Knigge RM, Drummond J, Nishimura M. HTLV-II infection in Florida Indians. Aids Research and Human Retroviruses. 9: 123-7. PMID 8457379 DOI: 10.1089/Aid.1993.9.123  0.347
1993 Nishimura M, Mingioli E, McFarlin DE, Jacobson S. Demonstration of human T-cell lymphotrophic virus type I (HTLV-I) from an HTLV-I seronegative South Indian patient with chronic, progessive spastic paraparesis Annals of Neurology. 34: 867-870. PMID 8250538 DOI: 10.1002/Ana.410340618  0.439
1993 Wu E, Dickson DW, Jacobson S, Raine CS. Neuroaxonal dystrophy in HTLV-1-associated myelopathy/tropical spastic paraparesis: neuropathologic and neuroimmunologic correlations. Acta Neuropathologica. 86: 224-35. PMID 8213080 DOI: 10.1007/Bf00304136  0.395
1993 Davidson M, Braziel RM, Lairmore MD, Jacobson S, Sprott JM, Tucker SB, Levine PH, Kaplan JE. Atypical human T-cell lymphotropic virus type-I-associated T-cell lymphoma in a low-prevalence Alaska native population: Implications for disease surveillance Cancer. 71: 4072-4076. PMID 8099530 DOI: 10.1002/1097-0142(19930615)71:12<4072::Aid-Cncr2820711244>3.0.Co;2-O  0.443
1993 Nishimura M, McFarlin DE, Jacobson S. Sequence comparisons of HTLV‐I from HAM/TSP patients and their asymptomatic spouses Neurology. 43: 2621-2621. PMID 7504797 DOI: 10.1212/Wnl.43.12.2621  0.358
1992 Jacobson S, McFarlin DE, Robinson S, Voskuhl R, Martin R, Brewah A, Newell AJ, Koenig S. HTLV-I-specific cytotoxic T lymphocytes in the cerebrospinal fluid of patients with HTLV-I-associated neurological disease. Annals of Neurology. 32: 651-7. PMID 1449245 DOI: 10.1002/Ana.410320508  0.471
1992 Jacobson S. Immune response to retroviruses in the central nervous system Seminars in Neuroscience. 4: 285-290. DOI: 10.1016/1044-5765(92)90043-2  0.48
1991 Bever CT, Jacobson S, Mingioli ES, McFarland HF, McFarlin DE, Levy HB. Changes in leukocyte recirculation, NK cell activity, and HLA-DR expression in peripheral blood mononuclear cells of MS patients treated with Poly ICLC. International Journal of Immunopharmacology. 13: 613-8. PMID 1783475 DOI: 10.1016/0192-0561(91)90084-K  0.344
1991 Wiktor SZ, Blattner WA, Jacobson S, Reuben JS, MacFarlin DE, Weiss SH, Shaw GM, Short VJ. Spontaneous lymphocyte proliferation in HTLV-II infection. The Lancet. 337: 327-328. PMID 1671234 DOI: 10.1016/0140-6736(91)90947-N  0.361
1990 Jacobson S, Gupta A, Mattson D, Mingioli E, McFarlin DE. Immunological studies in tropical spastic paraparesis. Annals of Neurology. 27: 149-56. PMID 2317010 DOI: 10.1002/Ana.410270209  0.496
1990 Evangelista A, Maroushek S, Minnigan H, Larson A, Retzel E, Haase A, Gonzalez-Dunia D, McFarlin D, Mingioli E, Jacobson S, Osame M, Sonoda S. Nucleotide sequence analysis of a provirus derived from an individual with tropical spastic paraparesis Microbial Pathogenesis. 8: 259-278. PMID 2200942 DOI: 10.1016/0882-4010(90)90052-R  0.419
1990 Jacobson S, Shida H, McFarlin DE, Fauci AS, Koenig S. Circulating CD8 + cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease Nature. 348: 245-248. PMID 2146511 DOI: 10.1038/348245A0  0.489
1989 Dhib-Jalbut S, Jacobson S, McFarlin DE, McFarland HF. Impaired measles-specific cytotoxic T-cell response in subacute sclerosing panencephalitis. Annals of the New York Academy of Sciences. 540: 645-8. PMID 3264687 DOI: 10.1111/J.1749-6632.1988.Tb27199.X  0.335
1989 Dhib-Jalbut S, Jacobson S, McFarlin DE, McFarland HF. Impaired human leukocyte antigen-restricted measles virus-specific cytotoxic T-cell response in subacute sclerosing panencephalitis. Annals of Neurology. 25: 272-80. PMID 2786368 DOI: 10.1002/Ana.410250311  0.438
1989 Jacobson S, Sekaly RP, Jacobson CL, McFarland HF, Long EO. HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells Journal of Virology. 63: 1756-1762. PMID 2784508 DOI: 10.1128/Jvi.63.4.1756-1762.1989  0.384
1989 Long EO, Jacobson S. Pathways of viral antigen processing and presentation to CTL: defined by the mode of virus entry? Immunology Today. 10: 45-48. PMID 2665772 DOI: 10.1016/0167-5699(89)90303-4  0.326
1989 Greenberg SJ, Jacobson S, Waldmann TA, McFarlin DALEE. Molecular Analysis of Htlv-I Proviral Integration and T Cell Receptor Arrangement Indicates that T Cells in Tropical Spastic Paraparesis are Polyclonal Journal of Infectious Diseases. 159: 741-744. PMID 2538520 DOI: 10.1093/Infdis/159.4.741  0.31
1989 Goodman AD, Jacobson S, McFarland HF. Virus-specific cytotoxic T lymphocytes in multiple sclerosis: a normal mumps virus response adds support for a distinct impairment in the measles virus response. Journal of Neuroimmunology. 22: 201-9. PMID 2467918 DOI: 10.1016/0165-5728(89)90018-0  0.467
1988 McFarland HF, Goodman A, Jacobson S. Virus-specific cytotoxic T cells in multiple sclerosis. Annals of the New York Academy of Sciences. 532: 273-9. PMID 3263072 DOI: 10.1111/J.1749-6632.1988.Tb36345.X  0.449
1988 Sekaly RP, Jacobson S, Richert JR, Tonnelle C, McFarland HF, Long EO. Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain Proceedings of the National Academy of Sciences of the United States of America. 85: 1209-1212. PMID 3257576 DOI: 10.1073/Pnas.85.4.1209  0.39
1988 Jacobson S, Sekaly RP, Bellini WJ, Johnson CL, McFarland HF, Long EO. Recognition of intracellular measles virus antigens byt HLA class II restricted measles virus-specific cytotoxic T lymphocytes Annals of the New York Academy of Sciences. 540: 352-353. PMID 2905123 DOI: 10.1111/J.1749-6632.1988.Tb27096.X  0.379
1988 Jacobson S, Zaninovic V, Mora C, Rodgers-Johnson P, Sheremata WA, Gibbs CJ, Gajdusek C, McFarlin DE. Immunological findings in neurological diseases associated with antibodies to HTLV-I: activated lymphocytes in tropical spastic paraparesis. Annals of Neurology. 23: S196-200. PMID 2894814 DOI: 10.1002/Ana.410230744  0.387
1988 Jacobson S, Raine CS, Mingioli ES, McFarlin DE. Isolation of an HTLV-1-like retrovirus from patients with tropical spastic paraparesis. Nature. 331: 540-3. PMID 2829028 DOI: 10.1038/331540A0  0.461
1987 Jacobson S, Rose JW, Flerlage ML, McFarlin DE, McFarland HF. Induction of measles virus-specific human cytotoxic T cells by purified measles virus nucleocapsid and hemagglutinin polypeptides. Viral Immunology. 1: 153-62. PMID 3509946 DOI: 10.1089/Vim.1987.1.153  0.398
1987 Goodman AD, Jacobson S, McFarland HF. Mumps virus-specific cytotoxic T lympocyte responses can be mediated by class II MHC-restricted CD4+ cells Journal of Neuroimmunology. 16: 65. DOI: 10.1016/0165-5728(87)90228-1  0.389
1987 Dhib-Jalbut SS, Jacobson S, McFarlin DE, McFarland HF. Impaired measles-specific cytotoxic T-cell response in SSPE Journal of Neuroimmunology. 16: 42. DOI: 10.1016/0165-5728(87)90190-1  0.333
1986 Jacobson S, Sorrentino R, Nepom GT, McFarlin DE, Strominger JL. DNA restriction fragment length polymorphism of HLA-DR2: correlation with HLA-DR2-associated functions. Journal of Neuroimmunology. 12: 195-203. PMID 3016025 DOI: 10.1016/S0165-5728(86)80003-0  0.314
1985 Jacobson S, Nepom GT, Richert JR, Biddison WE, McFarland HF. Identification of a specific HLA DR2 Ia molecule as a restriction element for measles virus-specific HLA class II-restricted cytotoxic T cell clones. The Journal of Experimental Medicine. 161: 263-8. PMID 2578544 DOI: 10.1084/Jem.161.1.263  0.347
1985 Jacobson S, Flerlage ML, McFarland HF. Impaired measles virus-specific cytotoxic T cell responses in multiple sclerosis. The Journal of Experimental Medicine. 162: 839-50. PMID 2411841 DOI: 10.1084/Jem.162.3.839  0.457
1985 Jacobson S, Rose JW, McFarlin DE, McFarland HF. Measles virus-specific cytotoxic T cell responses to purified measles virus antigens Virus Research. 3: 55. DOI: 10.1016/0168-1702(85)90362-4  0.409
1984 Greenstein JI, Jacobson S, Richert JR, McFarland HF. Characterization of antigen-specific T cells in multiple sclerosis twins with elevated responses to measles virus. Annals of the New York Academy of Sciences. 436: 511-2. PMID 6085229 DOI: 10.1111/J.1749-6632.1984.Tb14834.X  0.443
1983 Jacobson S, McFarland HF. Measles virus persistence in human lymphocytes: a role for virus-induced interferon. The Journal of General Virology. 63: 351-7. PMID 7153763 DOI: 10.1099/0022-1317-63-2-351  0.428
1981 Jacobson S, Friedman RM, Pfau CJ. Interferon induction by lymphocytic choriomeningitis viruses correlates with maximum virulence. The Journal of General Virology. 57: 275-83. PMID 6172554 DOI: 10.1099/0022-1317-57-2-275  0.783
1980 Jacobson S, Pfau CJ. Viral pathogenesis and resistance to defective interfering particles Nature. 283: 311-313. PMID 7352005 DOI: 10.1038/283311A0  0.784
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