| Year |
Citation |
Score |
| 2023 |
Lagou V, Jiang L, Ulrich A, Zudina L, González KSG, Balkhiyarova Z, Faggian A, Maina JG, Chen S, Todorov PV, Sharapov S, David A, Marullo L, Mägi R, Rujan RM, ... ... van Duijn CM, et al. GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification. Nature Genetics. 55: 1448-1461. PMID 37679419 DOI: 10.1038/s41588-023-01462-3 |
0.301 |
|
| 2023 |
Luo J, Thomassen JQ, Bellenguez C, Grenier-Boley B, de Rojas I, Castillo A, Parveen K, Küçükali F, Nicolas A, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Jürgen D, ... ... Van Duijn C, et al. Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease. Jama Network Open. 6: e2313734. PMID 37195665 DOI: 10.1001/jamanetworkopen.2023.13734 |
0.502 |
|
| 2023 |
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... van Duijn CM, et al. Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 14: 716. PMID 36759603 DOI: 10.1038/s41467-023-36192-x |
0.508 |
|
| 2022 |
Young KL, Fisher V, Deng X, Brody JA, Graff M, Lim E, Lin BM, Xu H, Amin N, An P, Aslibekyan S, Fohner AE, Hidalgo B, Lenzini P, Kraaij R, ... ... van Duijn CM, et al. Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants. Hgg Advances. 4: 100163. PMID 36568030 DOI: 10.1016/j.xhgg.2022.100163 |
0.366 |
|
| 2022 |
Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N, Norsworthy PJ, Dols-Icardo O, Hummerich H, Kawalia A, Amouyel P, ... ... van Duijn CM, et al. Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease. Nature Genetics. PMID 36411364 DOI: 10.1038/s41588-022-01208-7 |
0.549 |
|
| 2022 |
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, ... ... van Duijn CM, et al. A saturated map of common genetic variants associated with human height. Nature. PMID 36224396 DOI: 10.1038/s41586-022-05275-y |
0.366 |
|
| 2022 |
Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, ... ... van Duijn CM, et al. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathologica. PMID 36066633 DOI: 10.1007/s00401-022-02454-z |
0.658 |
|
| 2022 |
Young WJ, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody JA, Salman R, Noordam R, Benjamins JW, Haessler J, Lyytikäinen LP, Repetto L, Concas MP, van den Berg ME, ... ... van Duijn CM, et al. Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature Communications. 13: 5144. PMID 36050321 DOI: 10.1038/s41467-022-32821-z |
0.307 |
|
| 2022 |
Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger SJ, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, ... ... van Duijn C, et al. Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. Jama Neurology. PMID 35639372 DOI: 10.1001/jamaneurol.2022.1166 |
0.666 |
|
| 2022 |
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... van Duijn CM, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z |
0.681 |
|
| 2021 |
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, ... ... van Duijn CM, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. PMID 34887591 DOI: 10.1038/s41586-021-04064-3 |
0.324 |
|
| 2021 |
Reus LM, Jansen IE, Mol MO, van Ruissen F, van Rooij J, van Schoor NM, Tesi N, Reinders MJT, Huisman MA, Holstege H, Visser PJ, de Boer SCM, Hulsman M, Ahmad S, Amin N, ... ... van Duijn CM, et al. Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions. Translational Psychiatry. 11: 451. PMID 34475377 DOI: 10.1038/s41398-021-01577-3 |
0.609 |
|
| 2021 |
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... van Duijn CM, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8 |
0.557 |
|
| 2021 |
Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segrè AV, Rouhana JM, Hamel AR, Igo RP, Choquet H, Qassim A, Josyula NS, ... ... van Duijn C, et al. Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications. 12: 1258. PMID 33627673 DOI: 10.1038/s41467-020-20851-4 |
0.353 |
|
| 2021 |
Kurilshikov A, Medina-Gomez C, Bacigalupe R, Radjabzadeh D, Wang J, Demirkan A, Le Roy CI, Raygoza Garay JA, Finnicum CT, Liu X, Zhernakova DV, Bonder MJ, Hansen TH, Frost F, Rühlemann MC, ... ... van Duijn CM, et al. Large-scale association analyses identify host factors influencing human gut microbiome composition. Nature Genetics. PMID 33462485 DOI: 10.1038/s41588-020-00763-1 |
0.347 |
|
| 2020 |
Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, ... ... Van Duijn CM, et al. Cerebral small vessel disease genomics and its implications across the lifespan. Nature Communications. 11: 6285. PMID 33293549 DOI: 10.1038/s41467-020-19111-2 |
0.305 |
|
| 2020 |
Cuellar-Partida G, Tung JY, Eriksson N, Albrecht E, Aliev F, Andreassen OA, Barroso I, Beckmann JS, Boks MP, Boomsma DI, Boyd HA, Breteler MMB, Campbell H, Chasman DI, Cherkas LF, ... ... van Duijn CM, et al. Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour. PMID 32989287 DOI: 10.1038/s41562-020-00956-y |
0.304 |
|
| 2020 |
Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, ... ... van Duijn CM, et al. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications. 11: 4796. PMID 32963231 DOI: 10.1038/s41467-020-18367-y |
0.406 |
|
| 2020 |
Karamujić-Čomić H, Ahmad S, Lysen TS, Heshmatollah A, Roshchupkin GV, Vernooij MW, Rozemuller AJM, Ikram MA, Amin N, van Duijn CM. Prion protein codon 129 polymorphism in mild cognitive impairment and dementia: the Rotterdam Study. Brain Communications. 2: fcaa030. PMID 32954288 DOI: 10.1093/braincomms/fcaa030 |
0.307 |
|
| 2020 |
Knol MJ, Lu D, Traylor M, Adams HH, Rafael J Romero J, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, ... ... van Duijn CM, et al. Association of common genetic variants with brain microbleeds: A Genome-wide Association Study. Neurology. PMID 32913026 DOI: 10.1212/Wnl.0000000000010852 |
0.304 |
|
| 2020 |
Weng LC, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H, Teumer A, Li-Gao R, Yao J, Guo X, Brody JA, Müller-Nurasyid M, Schramm K, ... ... van Duijn CM, et al. Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation. Circulation. Genomic and Precision Medicine. PMID 32822252 DOI: 10.1161/CIRCGEN.119.002874 |
0.314 |
|
| 2020 |
van der Spek A, Warner SC, Broer L, Nelson CP, Vojinovic D, Ahmad S, Arp PP, Brouwer RWW, Denniff M, van den Hout MCGN, van Rooij JGJ, Kraaij R, van IJcken WFJ, Samani NJ, Ikram MA, ... ... van Duijn CM, et al. Exome Sequencing Analysis Identifies Rare Variants in and That Are Associated With Shorter Telomere Length. Frontiers in Genetics. 11: 337. PMID 32425970 DOI: 10.3389/fgene.2020.00337 |
0.341 |
|
| 2020 |
Li C, Stoma S, Lotta LA, Warner S, Albrecht E, Allione A, Arp PP, Broer L, Buxton JL, Da Silva Couto Alves A, Deelen J, Fedko IO, Gordon SD, Jiang T, Karlsson R, ... ... van Duijn CM, et al. Genome-Wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. American Journal of Human Genetics. PMID 32109421 DOI: 10.1016/J.Ajhg.2020.02.006 |
0.328 |
|
| 2019 |
Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, ... ... van Duijn CM, et al. GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Science Advances. 5: eaaw3095. PMID 31840077 DOI: 10.1126/Sciadv.Aaw3095 |
0.365 |
|
| 2019 |
Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, ... ... van Duijn CM, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. PMID 31636452 DOI: 10.1038/S41588-019-0511-Y |
0.389 |
|
| 2019 |
Bot M, Milaneschi Y, Al-Shehri T, Amin N, Garmaeva S, Onderwater GLJ, Pool R, Thesing CS, Vijfhuizen LS, Vogelzangs N, Arts ICW, Demirkan A, van Duijn C, van Greevenbroek M, van der Kallen CJH, et al. Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. Biological Psychiatry. PMID 31635762 DOI: 10.1016/J.Biopsych.2019.08.016 |
0.319 |
|
| 2019 |
Deelen J, Kettunen J, Fischer K, van der Spek A, Trompet S, Kastenmüller G, Boyd A, Zierer J, van den Akker EB, Ala-Korpela M, Amin N, Demirkan A, Ghanbari M, van Heemst D, Ikram MA, ... ... van Duijn CM, et al. A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nature Communications. 10: 3346. PMID 31431621 DOI: 10.1038/s41467-019-11311-9 |
0.358 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... van Duijn CM, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7 |
0.529 |
|
| 2019 |
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, ... ... van Duijn CM, et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications. 10: 3669. PMID 31413261 DOI: 10.1038/S41467-019-11558-2 |
0.321 |
|
| 2019 |
Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai PC, Martin TC, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, ... ... van Duijn CM, et al. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications. 10: 2581. PMID 31197173 DOI: 10.1038/S41467-019-10487-4 |
0.373 |
|
| 2019 |
Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW, Bis JC, Debette S, DeStefano AL, Fornage M, Nicolas G, ... van Duijn C, et al. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. Jama Neurology. PMID 31180460 DOI: 10.1001/Jamaneurol.2019.1456 |
0.329 |
|
| 2019 |
Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, ... ... van Duijn CM, et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. American Journal of Human Genetics. PMID 31178129 DOI: 10.1016/J.Ajhg.2019.05.002 |
0.325 |
|
| 2019 |
Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, ... ... van Duijn CM, et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics. PMID 31127295 DOI: 10.1093/Hmg/Ddz070 |
0.365 |
|
| 2019 |
Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, ... ... van Duijn CM, et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. PMID 31043758 DOI: 10.1038/S41588-019-0403-1 |
0.325 |
|
| 2019 |
Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, ... ... van Duijn CM, et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 51: 636-648. PMID 30926973 DOI: 10.1038/S41588-019-0378-Y |
0.425 |
|
| 2019 |
Mishra A, Chauhan G, Violleau MH, Vojinovic D, Jian X, Bis JC, Li S, Saba Y, Grenier-Boley B, Yang Q, Bartz TM, Hofer E, Soumaré A, Peng F, Duperron MG, ... ... Van Duijn CM, et al. Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects. Brain : a Journal of Neurology. PMID 30859180 DOI: 10.1093/Brain/Awz024 |
0.349 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... van Duijn CM, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2 |
0.588 |
|
| 2019 |
Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, ... ... van Duijn CM, et al. Disentangling the genetics of lean mass. The American Journal of Clinical Nutrition. PMID 30721968 DOI: 10.1093/Ajcn/Nqy272 |
0.495 |
|
| 2019 |
van Setten J, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I, Grarup N, Hall LM, Hemerich D, Lyytikäinen LP, Mei H, Müller-Nurasyid M, Prins BP, ... ... van Duijn CM, et al. Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics : Ejhg. PMID 30679814 DOI: 10.1038/S41431-018-0295-Z |
0.369 |
|
| 2019 |
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, ... ... van Duijn CM, et al. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. PMID 30651383 DOI: 10.1212/Wnl.0000000000006851 |
0.326 |
|
| 2018 |
Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, ... ... van Duijn CM, et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature Communications. 9: 5141. PMID 30510157 DOI: 10.1038/S41467-018-07340-5 |
0.393 |
|
| 2018 |
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, ... ... van Duijn CM, et al. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30429575 DOI: 10.1038/S41588-018-0297-3 |
0.499 |
|
| 2018 |
Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min JL, Chen L, Astle W, Cocca M, Deelen P, Elding H, Farmaki AE, Franklin CS, Franberg M, ... ... van Duijn CM, et al. Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nature Genetics. PMID 30390057 DOI: 10.1038/S41588-018-0276-8 |
0.356 |
|
| 2018 |
Vojinovic D, Kavousi M, Ghanbari M, Brouwer RWW, van Rooij JGJ, van den Hout MCGN, Kraaij R, van Ijcken WFJ, Uitterlinden AG, van Duijn CM, Amin N. Whole-Genome Linkage Scan Combined With Exome Sequencing Identifies Novel Candidate Genes for Carotid Intima-Media Thickness. Frontiers in Genetics. 9: 420. PMID 30356672 DOI: 10.3389/fgene.2018.00420 |
0.36 |
|
| 2018 |
Bonnemaijer PWM, Iglesias AI, Nadkarni GN, Sanyiwa AJ, Hassan HG, Cook C, Simcoe M, Taylor KD, Schurmann C, Belbin GM, Kenny EE, Bottinger EP, van de Laar S, Wiliams SEI, ... ... van Duijn CM, et al. Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations. Human Genetics. PMID 30317457 DOI: 10.1007/s00439-018-1943-7 |
0.38 |
|
| 2018 |
Wong TH, van der Lee SJ, van Rooij JGJ, Meeter LHH, Frick P, Melhem S, Seelaar H, Ikram MA, Rozemuller AJ, Holstege H, Hulsman M, Uitterlinden A, Neumann M, Hoozemans JJM, van Duijn CM, et al. EIF2AK3 variants in Dutch patients with Alzheimer's disease. Neurobiology of Aging. PMID 30314817 DOI: 10.1016/j.neurobiolaging.2018.08.016 |
0.525 |
|
| 2018 |
Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, ... ... van Duijn CM, et al. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nature Communications. 9: 3945. PMID 30258056 DOI: 10.1038/S41467-018-06234-W |
0.777 |
|
| 2018 |
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, ... ... van Duijn CM, et al. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30224653 DOI: 10.1038/S41588-018-0205-X |
0.487 |
|
| 2018 |
Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, ... ... van Duijn CM, et al. Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. Neurobiology of Aging. PMID 30201328 DOI: 10.1016/J.Neurobiolaging.2018.08.001 |
0.592 |
|
| 2018 |
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... van Duijn CM, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7 |
0.324 |
|
| 2018 |
Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Wenocur A, ... ... van Duijn CM, et al. Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nature Genetics. PMID 29808027 DOI: 10.1038/s41588-018-0127-7 |
0.334 |
|
| 2018 |
Iglesias AI, Mishra A, Vitart V, Bykhovskaya Y, Höhn R, Springelkamp H, Cuellar-Partida G, Gharahkhani P, Bailey JNC, Willoughby CE, Li X, Yazar S, Nag A, Khawaja AP, Polašek O, ... ... van Duijn CM, et al. Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nature Communications. 9: 1864. PMID 29760442 DOI: 10.1038/S41467-018-03646-6 |
0.309 |
|
| 2018 |
Nedeljkovic I, Terzikhan N, Vonk JM, van der Plaat DA, Lahousse L, van Diemen CC, Hobbs BD, Qiao D, Cho MH, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N. A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants. Frontiers in Genetics. 9: 133. PMID 29725345 DOI: 10.3389/fgene.2018.00133 |
0.313 |
|
| 2018 |
Corominas J, Colijn JM, Geerlings MJ, Pauper M, Bakker B, Amin N, Lores Motta L, Kersten E, Garanto A, Verlouw JAM, van Rooij JGJ, Kraaij R, de Jong PTVM, Hofman A, Vingerling JR, ... ... van Duijn CM, et al. Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch's Membrane. Ophthalmology. PMID 29706360 DOI: 10.1016/J.Ophtha.2018.03.040 |
0.412 |
|
| 2018 |
Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, ... ... van Duijn CM, et al. Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability. Nature Genetics. PMID 29662168 DOI: 10.1038/S41588-018-0100-5 |
0.333 |
|
| 2018 |
van der Lee SJ, Wolters FJ, Ikram MK, Hofman A, Ikram MA, Amin N, van Duijn CM. The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. The Lancet. Neurology. PMID 29555425 DOI: 10.1016/S1474-4422(18)30053-X |
0.382 |
|
| 2018 |
Silva CT, Zorkoltseva IV, Niemeijer MN, van den Berg ME, Amin N, Demirkan A, van Leeuwen E, Iglesias AI, Piñeros-Hernández LB, Restrepo CM, Kors JA, Kirichenko AV, Willemsen R, Oostra BA, Stricker BH, ... ... van Duijn CM, et al. A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy. Bmc Medical Genomics. 11: 22. PMID 29506515 DOI: 10.1186/s12920-018-0339-9 |
0.476 |
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| 2018 |
Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, ... ... van Duijn CM, et al. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. American Journal of Human Genetics. PMID 29455858 DOI: 10.1016/J.Ajhg.2018.01.015 |
0.446 |
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| 2018 |
de Vrij FM, Bouwkamp CG, Gunhanlar N, Shpak G, Lendemeijer B, Baghdadi M, Gopalakrishna S, Ghazvini M, Li TM, Quadri M, Olgiati S, Breedveld GJ, Coesmans M, Mientjes E, de Wit T, ... ... van Duijn CM, et al. Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia. Molecular Psychiatry. PMID 29302076 DOI: 10.1038/S41380-017-0004-2 |
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| 2017 |
Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, et al. Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits. Psychosomatic Medicine. PMID 29280852 DOI: 10.1097/Psy.0000000000000555 |
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| 2017 |
Xiao X, Wang L, Wang C, Yuan TF, Zhou D, Zheng F, Li L, Grigoroiu-Serbanescu M, Ikeda M, Iwata N, Takahashi A, Kamatani Y, Kubo M, Preisig M, Kutalik Z, ... ... van Duijn CM, et al. Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders. Translational Psychiatry. 7: 1273. PMID 29225345 DOI: 10.1038/S41398-017-0019-0 |
0.319 |
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| 2017 |
Liu F, Chen Y, Zhu G, Hysi PG, Wu S, Adhikari K, Breslin K, Pospiech E, Hamer MA, Peng F, Muralidharan C, Acuna-Alonzo V, Canizales-Quinteros S, Bedoya G, Gallo C, ... ... van Duijn CM, et al. Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair. Human Molecular Genetics. PMID 29220522 DOI: 10.1093/Hmg/Ddx416 |
0.332 |
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| 2017 |
Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, ... ... van Duijn CM, et al. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications. 8: 1414. PMID 29116125 DOI: 10.1038/s41467-017-01008-2 |
0.533 |
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| 2017 |
van der Spek A, Luik AI, Kocevska D, Liu C, Brouwer RWW, van Rooij JGJ, van den Hout MCGN, Kraaij R, Hofman A, Uitterlinden AG, van IJcken WFJ, Gottlieb DJ, Tiemeier H, van Duijn CM, Amin N. Exome-Wide Meta-Analysis Identifies Rare 3'-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea. Frontiers in Genetics. 8: 151. PMID 29093733 DOI: 10.3389/Fgene.2017.00151 |
0.498 |
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| 2017 |
Nedeljkovic I, Lahousse L, Carnero Montoro E, Faiz A, Vonk JM, de Jong K, van der Plaat DA, van Diemen CC, van den Berge M, Obeidat M, Bossé Y, Nickle DC, Uitterlinden AG, van Meurs JBJ, ... ... van Duijn CM, et al. COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression. Human Molecular Genetics. PMID 29092026 DOI: 10.1093/hmg/ddx390 |
0.313 |
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| 2017 |
Ikram MA, Brusselle GGO, Murad SD, van Duijn CM, Franco OH, Goedegebure A, Klaver CCW, Nijsten TEC, Peeters RP, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Hofman A. The Rotterdam Study: 2018 update on objectives, design and main results. European Journal of Epidemiology. PMID 29064009 DOI: 10.1007/S10654-017-0321-4 |
0.442 |
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| 2017 |
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N, Drenos F, Sim X, Smith AV, Amin N, Blakemore AIF, Bork-Jensen J, Brandslund I, ... ... van Duijn CM, et al. New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation. Cardiovascular Genetics. 10. PMID 29030403 DOI: 10.1161/Circgenetics.117.001778 |
0.315 |
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| 2017 |
Sniekers S, Stringer S, Watanabe K, Jansen PR, Coleman JRI, Krapohl E, Taskesen E, Hammerschlag AR, Okbay A, Zabaneh D, Amin N, Breen G, Cesarini D, Chabris CF, Iacono WG, ... ... van Duijn CM, et al. Erratum: Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Nature Genetics. 49: 1558. PMID 28951626 DOI: 10.1038/ng1017-1558c |
0.482 |
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| 2017 |
Christophersen IE, Magnani JW, Yin X, Barnard J, Weng LC, Arking DE, Niemeijer MN, Lubitz SA, Avery CL, Duan Q, Felix SB, Bis JC, Kerr KF, Isaacs A, Müller-Nurasyid M, ... ... van Duijn C, et al. Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. Circulation. Cardiovascular Genetics. 10. PMID 28794112 DOI: 10.1161/Circgenetics.116.001667 |
0.306 |
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| 2017 |
Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, ... ... van Duijn CM, et al. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension (Dallas, Tex. : 1979). PMID 28739976 DOI: 10.1161/Hypertensionaha.117.09438 |
0.527 |
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| 2017 |
Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, ... ... van Duijn CM, et al. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications. 8: 80. PMID 28724990 DOI: 10.1038/S41467-017-00031-7 |
0.529 |
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| 2017 |
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... van Duijn CM, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
0.64 |
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| 2017 |
Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, ... ... van Duijn CM, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/Db16-1253 |
0.351 |
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| 2017 |
Holstege H, van der Lee SJ, Hulsman M, Wong TH, van Rooij JG, Weiss M, Louwersheimer E, Wolters FJ, Amin N, Uitterlinden AG, Hofman A, Ikram MA, van Swieten JC, Meijers-Heijboer H, van der Flier WM, ... ... van Duijn CM, et al. Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy. European Journal of Human Genetics : Ejhg. PMID 28537274 DOI: 10.1038/Ejhg.2017.87 |
0.619 |
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| 2017 |
Sniekers S, Stringer S, Watanabe K, Jansen PR, Coleman JRI, Krapohl E, Taskesen E, Hammerschlag AR, Okbay A, Zabaneh D, Amin N, Breen G, Cesarini D, Chabris CF, Iacono WG, ... ... van Duijn CM, et al. Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Nature Genetics. PMID 28530673 DOI: 10.1038/Ng.3869 |
0.51 |
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| 2017 |
Vojinovic D, Brison N, Ahmad S, Noens I, Pappa I, Karssen LC, Tiemeier H, van Duijn CM, Peeters H, Amin N. Variants in TTC25 affect autistic trait in patients with autism spectrum disorder and general population. European Journal of Human Genetics : Ejhg. PMID 28513607 DOI: 10.1038/ejhg.2017.82 |
0.516 |
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| 2017 |
Iglesias AI, van der Lee SJ, Bonnemaijer PWM, Höhn R, Nag A, Gharahkhani P, Khawaja AP, Broer L, Foster PJ, Hammond CJ, Hysi PG, van Leeuwen EM, MacGregor S, Mackey DA, ... ... van Duijn CM, et al. Haplotype reference consortium panel: Practical implications of imputations with large reference panels. Human Mutation. PMID 28493391 DOI: 10.1002/Humu.23247 |
0.335 |
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| 2017 |
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... van Duijn CM, et al. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006528. PMID 28448500 DOI: 10.1371/Journal.Pgen.1006528 |
0.363 |
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| 2017 |
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, ... ... van Duijn CM, et al. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications. 8: 14977. PMID 28443625 DOI: 10.1038/Ncomms14977 |
0.445 |
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| 2017 |
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, Stirrups KE, ... ... van Duijn CM, et al. Rare and low-frequency coding variants alter human adult height. Nature. PMID 28146470 DOI: 10.1038/Nature21039 |
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| 2017 |
Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Van Duijn CM, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624 |
0.423 |
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| 2017 |
Springelkamp H, Iglesias AI, Mishra A, Höhn R, Wojciechowski R, Khawaja AP, Nag A, Wang YX, Wang JJ, Cuellar-Partida G, Gibson J, Cooke Bailey JN, Vithana EN, Gharahkhani P, Boutin T, ... ... van Duijn CM, et al. New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Human Molecular Genetics. PMID 28073927 DOI: 10.1093/Hmg/Ddw399 |
0.548 |
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| 2017 |
Kooijman MN, Kruithof CJ, van Duijn CM, Duijts L, Franco OH, van IJzendoorn MH, de Jongste JC, Klaver CC, van der Lugt A, Mackenbach JP, Moll HA, Peeters RP, Raat H, Rings EH, Rivadeneira F, et al. The Generation R Study: design and cohort update 2017. European Journal of Epidemiology. PMID 28070760 DOI: 10.1007/s10654-016-0224-9 |
0.383 |
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| 2016 |
Ikram MA, Vernooij MW, Roshchupkin GV, Hofman A, van Duijn CM, Uitterlinden AG, Niessen WJ, Hintzen RQ, Adams HH. Genetic susceptibility to multiple sclerosis: Brain structure and cognitive function in the general population. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458516682104. PMID 28273768 DOI: 10.1177/1352458516682104 |
0.318 |
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| 2016 |
Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttenschøn HN, Byrne EM, Børglum AD, ... ... van Duijn CM, et al. An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biological Psychiatry. PMID 28049566 DOI: 10.1016/J.Biopsych.2016.11.013 |
0.482 |
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| 2016 |
van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, ... ... van Duijn CM, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. PMID 28017375 DOI: 10.1016/J.Ajhg.2016.11.016 |
0.451 |
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| 2016 |
Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, ... ... van Duijn C, et al. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature. PMID 28002404 DOI: 10.1038/Nature20784 |
0.378 |
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| 2016 |
Roshchupkin GV, Gutman BA, Vernooij MW, Jahanshad N, Martin NG, Hofman A, McMahon KL, van der Lee SJ, van Duijn CM, de Zubicaray GI, Uitterlinden AG, Wright MJ, Niessen WJ, Thompson PM, Ikram MA, et al. Heritability of the shape of subcortical brain structures in the general population. Nature Communications. 7: 13738. PMID 27976715 DOI: 10.1038/Ncomms13738 |
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| 2016 |
Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, ... ... van Duijn CM, et al. Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics. PMID 27918535 DOI: 10.1038/Ng.3721 |
0.392 |
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| 2016 |
Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van 't Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, ... ... van Duijn CM, et al. Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics. PMID 27918533 DOI: 10.1038/Ng.3737 |
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| 2016 |
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... van Duijn CM, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 1591. PMID 27898078 DOI: 10.1038/Ng1216-1587B |
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| 2016 |
Silva CT, Zorkoltseva IV, Amin N, Demirkan A, van Leeuwen EM, Kors JA, van den Berg M, Stricker BH, Uitterlinden AG, Kirichenko AV, Witteman JC, Willemsen R, Oostra BA, Axenovich TI, van Duijn CM, et al. A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study. Frontiers in Genetics. 7: 190. PMID 27877193 DOI: 10.3389/fgene.2016.00190 |
0.54 |
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| 2016 |
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, ... ... van Duijn CM, et al. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications. 7: 13357. PMID 27876822 DOI: 10.1038/Ncomms13357 |
0.555 |
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| 2016 |
Natarajan P, Bis JC, Bielak LF, Cox AJ, Dörr M, Feitosa MF, Franceschini N, Guo X, Hwang SJ, Isaacs A, Jhun MA, Kavousi M, Li-Gao R, Lyytikäinen LP, Marioni RE, ... ... van Duijn CM, et al. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circulation. Cardiovascular Genetics. PMID 27872105 DOI: 10.1161/Circgenetics.116.001572 |
0.4 |
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| 2016 |
Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A, ... ... van Duijn CM, et al. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genetics. PMID 27798627 DOI: 10.1038/Ng.3698 |
0.468 |
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| 2016 |
Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, ... ... van Duijn CM, et al. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. Plos Genetics. 12: e1006327. PMID 27764101 DOI: 10.1371/Journal.Pgen.1006327 |
0.408 |
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| 2016 |
Amin N, Belonogova NM, Jovanova O, Brouwer RW, van Rooij JG, van den Hout MC, Svishcheva GR, Kraaij R, Zorkoltseva IV, Kirichenko AV, Hofman A, Uitterlinden AG, van IJcken WF, Tiemeier H, Axenovich TI, ... van Duijn CM, et al. Nonsynonymous Variation in NKPD1 Increases Depressive Symptoms in the European Populations. Biological Psychiatry. PMID 27745872 DOI: 10.1016/J.Biopsych.2016.08.008 |
0.486 |
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| 2016 |
Roshchupkin GV, Adams HH, van der Lee SJ, Vernooij MW, van Duijn CM, Uitterlinden AG, van der Lugt A, Hofman A, Niessen WJ, Ikram MA. Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology. Neurobiology of Aging. 48: 204-211. PMID 27718423 DOI: 10.1016/J.Neurobiolaging.2016.08.024 |
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| 2016 |
Hehir-Kwa JY, Marschall T, Kloosterman WP, Francioli LC, Baaijens JA, Dijkstra LJ, Abdellaoui A, Koval V, Thung DT, Wardenaar R, Renkens I, Coe BP, Deelen P, de Ligt J, Lameijer EW, ... ... van Duijn CM, et al. A high-quality human reference panel reveals the complexity and distribution of genomic structural variants. Nature Communications. 7: 12989. PMID 27708267 DOI: 10.1038/Ncomms12989 |
0.3 |
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| 2016 |
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, ... ... Van Duijn CM, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/Nn.4398 |
0.563 |
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| 2016 |
Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, ... ... van Duijn CM, et al. Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. 48: 1296. PMID 27681292 DOI: 10.1038/Ng1016-1296C |
0.371 |
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| 2016 |
Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, ... ... van Duijn CM, et al. Genome-wide associations for birth weight and correlations with adult disease. Nature. PMID 27680694 DOI: 10.1038/Nature19806 |
0.47 |
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| 2016 |
van Ingen G, Li J, Goedegebure A, Pandey R, Li YR, March ME, Jaddoe VW, Bakay M, Mentch FD, Thomas K, Wei Z, Chang X, Hain HS, Uitterlinden AG, Moll HA, ... van Duijn CM, et al. Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene. Nature Communications. 7: 12792. PMID 27677580 DOI: 10.1038/Ncomms12792 |
0.349 |
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| 2016 |
Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min JL, Chen L, Astle W, Cocca M, Deelen P, Elding H, Farmaki AE, Franklin CS, Franberg M, ... ... van Duijn CM, et al. Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nature Genetics. PMID 27668658 DOI: 10.1038/Ng.3668 |
0.467 |
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| 2016 |
van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, ... ... van Duijn CM, et al. 52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology. 68: 1435-48. PMID 27659466 DOI: 10.1016/J.Jacc.2016.07.729 |
0.45 |
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| 2016 |
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, ... ... van Duijn CM, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics. PMID 27618452 DOI: 10.1038/Ng.3667 |
0.359 |
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| 2016 |
Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC, Lu Y, Weiss S, Guo X, Palmas W, Martin LW, Chen YI, Surendran P, ... ... van Duijn CM, et al. Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nature Genetics. PMID 27618448 DOI: 10.1038/Ng.3660 |
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| 2016 |
Khawaja AP, Springelkamp H, Creuzot-Garcher C, Delcourt C, Hofman A, Höhn R, Iglesias AI, Wolfs RC, Korobelnik JF, Silva R, Topouzis F, Williams KM, Bron AM, Buitendijk GH, Cachulo MD, ... ... van Duijn CM, et al. Associations with intraocular pressure across Europe: The European Eye Epidemiology (E(3)) Consortium. European Journal of Epidemiology. PMID 27613171 DOI: 10.1007/S10654-016-0191-1 |
0.384 |
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| 2016 |
van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Brusselle GG, Hofman A, Brandsma CA, Bossé Y, Sin DD, Nickle DC, van Duijn CM, et al. Genome-wide association study on the FEV1/FVC-ratio in never-smokers identifies HHIP and FAM13A. The Journal of Allergy and Clinical Immunology. PMID 27612410 DOI: 10.1016/J.Jaci.2016.06.062 |
0.361 |
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| 2016 |
Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, ... ... van Duijn CM, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 785. PMID 27588453 DOI: 10.1016/J.Ajhg.2016.08.002 |
0.359 |
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| 2016 |
Pirastu N, Kooyman M, Robino A, van der Spek A, Navarini L, Amin N, Karssen LC, Van Duijn CM, Gasparini P. Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption. Scientific Reports. 6: 31590. PMID 27561104 DOI: 10.1038/Srep31590 |
0.311 |
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| 2016 |
Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, ... ... van Duijn CM, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 481-488. PMID 27486782 DOI: 10.1016/J.Ajhg.2016.06.016 |
0.397 |
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| 2016 |
Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... van Duijn CM, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 970. PMID 27463399 DOI: 10.1038/ng0816-970c |
0.514 |
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| 2016 |
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... van Duijn CM, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 12: e1006166. PMID 27355579 DOI: 10.1371/Journal.Pgen.1006166 |
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| 2016 |
Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, ... ... van Duijn CM, et al. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. American Journal of Human Genetics. PMID 27346685 DOI: 10.1016/J.Ajhg.2016.05.007 |
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| 2016 |
Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, ... ... van Duijn C, et al. Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27340842 DOI: 10.3233/Jad-150749 |
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| 2016 |
Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, ... ... van Duijn CM, et al. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. PMID 27329260 DOI: 10.1111/Acel.12490 |
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| 2016 |
Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, ... ... van Duijn CM, et al. Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. PMID 27322543 DOI: 10.1038/Ng.3598 |
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| 2016 |
Darweesh SK, Verlinden VJ, Adams HH, Uitterlinden AG, Hofman A, Stricker BH, van Duijn CM, Koudstaal PJ, Ikram MA. Genetic risk of Parkinson's disease in the general population. Parkinsonism & Related Disorders. PMID 27269966 DOI: 10.1016/J.Parkreldis.2016.05.030 |
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| 2016 |
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, ... ... van Duijn CM, et al. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 533: 539-42. PMID 27225129 DOI: 10.1038/Nature17671 |
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| 2016 |
Amin N, Allebrandt KV, van der Spek A, Müller-Myhsok B, Hek K, Teder-Laving M, Hayward C, Esko T, van Mill JG, Mbarek H, Watson NF, Melville SA, Del Greco FM, Byrne EM, Oole E, ... ... van Duijn CM, et al. Genetic variants in RBFOX3 are associated with sleep latency. European Journal of Human Genetics : Ejhg. PMID 27142678 DOI: 10.1038/Ejhg.2016.31 |
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| 2016 |
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... van Duijn CM, et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. PMID 27089181 DOI: 10.1038/Ng.3552 |
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| 2016 |
van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, ... ... van Duijn CM, et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics. PMID 27036123 DOI: 10.1136/Jmedgenet-2015-103439 |
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| 2016 |
Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, ... ... van Duijn CM, et al. Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nature Communications. 7: 11008. PMID 27020472 DOI: 10.1038/Ncomms11008 |
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| 2016 |
Parmar PG, Taal HR, Timpson NJ, Thiering E, Lehtimäki T, Marinelli M, Lind PA, Howe LD, Verwoert G, Aalto V, Uitterlinden AG, Briollais L, Evans DM, Wright MJ, Newnham JP, ... ... van Duijn CM, et al. International GWAS Consortium Identifies Novel Loci Associated with Blood Pressure in Children and Adolescents. Circulation. Cardiovascular Genetics. PMID 26969751 DOI: 10.1161/Circgenetics.115.001190 |
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| 2016 |
Adams H, Ikram MA, Vernooij MW, van Dijk AC, Hofman A, Uitterlinden AG, van Duijn CM, Koudstaal PJ, Franco OH, van der Lugt A, Bos D. Heritability and Genome-Wide Association Analyses of Intracranial Carotid Artery Calcification: The Rotterdam Study. Stroke; a Journal of Cerebral Circulation. PMID 26965845 DOI: 10.1161/Strokeaha.115.012248 |
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| 2016 |
Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J, ... ... van Duijn CM, et al. Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. Journal of Autoimmunity. PMID 26898941 DOI: 10.1016/J.Jaut.2016.01.002 |
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| 2016 |
Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, ... ... van Duijn CM, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 7: 10495. PMID 26833246 DOI: 10.1038/Ncomms10495 |
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| 2016 |
Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, ... ... van Duijn CM, et al. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications. 7: 10494. PMID 26833098 DOI: 10.1038/Ncomms10494 |
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| 2016 |
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, ... ... van Duijn CM, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications. 7: 10023. PMID 26831199 DOI: 10.1038/Ncomms10023 |
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| 2016 |
Akoudad S, Ikram MA, Portegies ML, Adams HH, Bos D, Hofman A, Koudstaal PJ, Uitterlinden AG, van der Lugt A, van Duijn CM, Vernooij MW. Genetic loci for serum lipid fractions and intracerebral hemorrhage. Atherosclerosis. 246: 287-292. PMID 26820804 DOI: 10.1016/J.Atherosclerosis.2016.01.024 |
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| 2016 |
Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, ... ... van Duijn CM, et al. Quantifying prion disease penetrance using large population control cohorts. Science Translational Medicine. 8: 322ra9. PMID 26791950 DOI: 10.1126/Scitranslmed.Aad5169 |
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| 2016 |
Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, ... ... van Duijn CM, et al. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nature Genetics. 48: 134-43. PMID 26691988 DOI: 10.1038/Ng.3448 |
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van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, ... ... van Duijn C, et al. Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. Npj Aging and Mechanisms of Disease. 1: 15011. PMID 28721259 DOI: 10.1038/npjamd.2015.11 |
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| 2015 |
Winsvold BS, Nelson CP, Malik R, Gormley P, Anttila V, Vander Heiden J, Elliott KS, Jacobsen LM, Palta P, Amin N, de Vries B, Hämäläinen E, Freilinger T, Ikram MA, Kessler T, ... ... van Duijn C, et al. Genetic analysis for a shared biological basis between migraine and coronary artery disease. Neurology. Genetics. 1: e10. PMID 27066539 DOI: 10.1212/Nxg.0000000000000010 |
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| 2015 |
Yu B, Pulit SL, Hwang SJ, Brody JA, Amin N, Auer PL, Bis JC, Boerwinkle E, Burke GL, Chakravarti A, Correa A, Dreisbach AW, Franco OH, Ehret GB, Franceschini N, ... ... van Duijn CM, et al. Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk. Circulation. Cardiovascular Genetics. PMID 26658788 DOI: 10.1161/Circgenetics.115.001215 |
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Jensen RA, Sim X, Smith AV, Li X, Jakobsdóttir J, Cheng CY, Brody JA, Cotch MF, McKnight B, Klein R, Wang JJ, Kifley A, Harris TB, Launer LJ, Taylor KD, ... ... van Duijn CM, et al. Novel Genetic Loci Associated with Retinal Microvascular Diameter. Circulation. Cardiovascular Genetics. PMID 26567291 DOI: 10.1161/Circgenetics.115.001142 |
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| 2015 |
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, ... ... van Duijn C, et al. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics. PMID 26551672 DOI: 10.1038/Ng.3437 |
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| 2015 |
Liu F, Hamer MA, Heilmann S, Herold C, Moebus S, Hofman A, Uitterlinden AG, Nöthen MM, van Duijn CM, Nijsten TE, Kayser M. Prediction of male-pattern baldness from genotypes. European Journal of Human Genetics : Ejhg. PMID 26508577 DOI: 10.1038/Ejhg.2015.220 |
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Hochner H, Allard C, Granot-Hershkovitz E, Chen J, Sitlani CM, Sazdovska S, Lumley T, McKnight B, Rice K, Enquobahrie DA, Meigs JB, Kwok P, Hivert MF, Borecki IB, Gomez F, ... ... van Duijn C, et al. Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults. Plos Genetics. 11: e1005573. PMID 26451733 DOI: 10.1371/Journal.Pgen.1005573 |
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Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, ... ... van Duijn CM, et al. White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. Stroke; a Journal of Cerebral Circulation. PMID 26451028 DOI: 10.1161/Strokeaha.115.009252 |
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Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... van Duijn CM, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 11: e1005378. PMID 26426971 DOI: 10.1371/Journal.Pgen.1005378 |
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Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, ... ... van Duijn CM, et al. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics. PMID 26414677 DOI: 10.1097/01.Ogx.0000473766.71624.99 |
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| 2015 |
Hofman A, Brusselle GG, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2016 objectives and design update. European Journal of Epidemiology. 30: 661-708. PMID 26386597 DOI: 10.1007/s10654-015-0082-x |
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| 2015 |
Silva CT, Kors JA, Amin N, Dehghan A, Witteman JC, Willemsen R, Oostra BA, van Duijn CM, Isaacs A. Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval. Human Genetics. PMID 26385552 DOI: 10.1007/s00439-015-1595-9 |
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Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, ... ... van Duijn CM, et al. Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. PMID 26367794 DOI: 10.1038/Nature14878 |
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| 2015 |
van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppälä I, Huffman JE, ... ... van Duijn CM, et al. Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behavior Genetics. PMID 26362575 DOI: 10.1007/S10519-015-9735-5 |
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| 2015 |
Peymani A, Adams HH, Cremers LG, Krestin G, Hofman A, van Duijn CM, Uitterlinden AG, van der Lugt A, Vernooij MW, Ikram MA. Genetic Determinants of Unruptured Intracranial Aneurysms in the General Population. Stroke; a Journal of Cerebral Circulation. PMID 26286545 DOI: 10.1161/Strokeaha.115.010414 |
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| 2015 |
van Leeuwen EM, Kanterakis A, Deelen P, Kattenberg MV, Slagboom PE, de Bakker PI, Wijmenga C, Swertz MA, Boomsma DI, van Duijn CM, Karssen LC, Hottenga JJ. Population-specific genotype imputations using minimac or IMPUTE2. Nature Protocols. 10: 1285-96. PMID 26226460 DOI: 10.1038/Nprot.2015.077 |
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| 2015 |
Adams HH, Verlinden VJ, Callisaya ML, van Duijn CM, Hofman A, Thomson R, Uitterlinden AG, Vernooij MW, van der Geest JN, Srikanth V, Ikram MA. Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26219847 DOI: 10.1093/Gerona/Glv081 |
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| 2015 |
Horikoshi M, M?gi R, van de Bunt M, Surakka I, Sarin AP, Mahajan A, Marullo L, Thorleifsson G, H?gg S, Hottenga JJ, Ladenvall C, Ried JS, Winkler TW, Willems SM, Pervjakova N, ... ... van Duijn CM, et al. Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. Plos Genetics. 11: e1005230. PMID 26132169 DOI: 10.1371/Journal.Pgen.1005230 |
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Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stančáková A, Faul JD, Zhao W, Bartz TM, ... ... van Duijn CM, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 523: 459-62. PMID 26131930 DOI: 10.1038/Nature14618 |
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Draisma HH, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AA, Yet I, Haller T, Demirkan A, Esko T, Zhu G, Böhringer S, Beekman M, van Klinken JB, Römisch-Margl W, ... ... van Duijn CM, et al. Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications. 6: 7208. PMID 26068415 DOI: 10.1038/Ncomms8208 |
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| 2015 |
Cuellar-Partida G, Springelkamp H, Lucas SE, Yazar S, Hewitt AW, Iglesias AI, Montgomery GW, Martin NG, Pennell CE, van Leeuwen EM, Verhoeven VJ, Hofman A, Uitterlinden AG, Ramdas WD, Wolfs RC, ... ... van Duijn CM, et al. WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness. Human Molecular Genetics. PMID 26049155 DOI: 10.1093/Hmg/Ddv211 |
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| 2015 |
Hägg S, Fall T, Ploner A, Mägi R, Fischer K, Draisma HH, Kals M, de Vries PS, Dehghan A, Willems SM, Sarin AP, Kristiansson K, Nuotio ML, Havulinna AS, de Bruijn RF, ... ... van Duijn CM, et al. Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. International Journal of Epidemiology. 44: 578-86. PMID 26016847 DOI: 10.1093/Ije/Dyv094 |
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Surakka I, Horikoshi M, Mägi R, Sarin AP, Mahajan A, Lagou V, Marullo L, Ferreira T, Miraglio B, Timonen S, Kettunen J, Pirinen M, Karjalainen J, Thorleifsson G, Hägg S, ... ... van Duijn CM, et al. The impact of low-frequency and rare variants on lipid levels. Nature Genetics. 47: 589-97. PMID 25961943 DOI: 10.1038/Ng.3300 |
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Adams HH, de Bruijn RF, Hofman A, Uitterlinden AG, van Duijn CM, Vernooij MW, Koudstaal PJ, Ikram MA. Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25916564 DOI: 10.1016/J.Jalz.2014.12.008 |
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| 2015 |
van der Lee SJ, Holstege H, Wong TH, Jakobsdottir J, Bis JC, Chouraki V, van Rooij JG, Grove ML, Smith AV, Amin N, Choi SH, Beiser AS, Garcia ME, van IJcken WF, Pijnenburg YA, ... ... van Duijn CM, et al. PLD3 variants in population studies. Nature. 520: E2-3. PMID 25832410 DOI: 10.1038/Nature14038 |
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| 2015 |
Huffman JE, Albrecht E, Teumer A, Mangino M, Kapur K, Johnson T, Kutalik Z, Pirastu N, Pistis G, Lopez LM, Haller T, Salo P, Goel A, Li M, Tanaka T, ... ... van Duijn CM, et al. Modulation of genetic associations with serum urate levels by body-mass-index in humans. Plos One. 10: e0119752. PMID 25811787 DOI: 10.1371/Journal.Pone.0119752 |
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| 2015 |
Medina-Gomez C, Felix JF, Estrada K, Peters MJ, Herrera L, Kruithof CJ, Duijts L, Hofman A, van Duijn CM, Uitterlinden AG, Jaddoe VW, Rivadeneira F. Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study. European Journal of Epidemiology. 30: 317-30. PMID 25762173 DOI: 10.1007/S10654-015-9998-4 |
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| 2015 |
Pirastu N, Kooyman M, Traglia M, Robino A, Willems SM, Pistis G, Amin N, Sala C, Karssen LC, van Duijn CM, Toniolo D, Gasparini P. Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking. European Journal of Human Genetics : Ejhg. PMID 25758996 DOI: 10.1038/Ejhg.2015.34 |
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van Leeuwen EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, van Enckevort DJ, Huffman JE, White CC, Feitosa MF, Bartz TM, ... ... van Duijn CM, et al. Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications. 6: 6065. PMID 25751400 DOI: 10.1038/Ncomms7065 |
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Fall T, Hägg S, Ploner A, Mägi R, Fischer K, Draisma HH, Sarin AP, Benyamin B, Ladenvall C, Åkerlund M, Kals M, Esko T, Nelson CP, Kaakinen M, Huikari V, ... ... van Duijn CM, et al. Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. Diabetes. 64: 1841-52. PMID 25712996 DOI: 10.2337/Db14-0988 |
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Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, ... ... van Duijn CM, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 518: 197-206. PMID 25673413 DOI: 10.1038/Nature14177 |
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Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, ... ... van Duijn CM, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518: 187-96. PMID 25673412 DOI: 10.1038/Nature14132 |
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Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, ... ... van Duijn CM, et al. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiology of Aging. 36: 1765.e7-16. PMID 25670335 DOI: 10.1016/J.Neurobiolaging.2014.12.028 |
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Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, ... ... van Duijn CM, et al. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circulation. Cardiovascular Genetics. 8: 398-409. PMID 25663218 DOI: 10.1161/Circgenetics.114.000858 |
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Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, ... ... van Duijn CM, et al. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biological Psychiatry. 77: 749-63. PMID 25648963 DOI: 10.1016/J.Biopsych.2014.08.027 |
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Springelkamp H, Iglesias AI, Cuellar-Partida G, Amin N, Burdon KP, van Leeuwen EM, Gharahkhani P, Mishra A, van der Lee SJ, Hewitt AW, Rivadeneira F, Viswanathan AC, Wolfs RC, Martin NG, Ramdas WD, ... ... van Duijn CM, et al. ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure. Human Molecular Genetics. 24: 2689-99. PMID 25637523 DOI: 10.1093/Hmg/Ddv027 |
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| 2015 |
Springelkamp H, Mishra A, Hysi PG, Gharahkhani P, Höhn R, Khor CC, Cooke Bailey JN, Luo X, Ramdas WD, Vithana E, Koh V, Yazar S, Xu L, Forward H, Kearns LS, ... ... van Duijn CM, et al. Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Genetic Epidemiology. 39: 207-16. PMID 25631615 DOI: 10.1002/Gepi.21886 |
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| 2015 |
Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, ... ... van Duijn CM, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 6: 5897. PMID 25631608 DOI: 10.1038/Ncomms6897 |
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| 2015 |
Demirkan A, Henneman P, Verhoeven A, Dharuri H, Amin N, van Klinken JB, Karssen LC, de Vries B, Meissner A, Göraler S, van den Maagdenberg AM, Deelder AM, C 't Hoen PA, van Duijn CM, van Dijk KW. Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses. Plos Genetics. 11: e1004835. PMID 25569235 DOI: 10.1371/journal.pgen.1004835 |
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| 2015 |
Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, ... ... van Duijn CM, et al. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Human Genetics. 134: 131-46. PMID 25367360 DOI: 10.1007/S00439-014-1500-Y |
0.613 |
|
| 2015 |
Plompen EP, Hansen BE, Schouten JN, Darwish Murad S, Loth DW, Brouwer WP, Isaacs A, Taimr P, Hofman A, van Duijn CM, Uitterlinden AG, Stricker BH, Leebeek FW, Janssen HL. Interferon gamma receptor 2 gene variants are associated with liver fibrosis in the general population: the Rotterdam Study. Gut. 64: 692-4. PMID 25301852 DOI: 10.1136/Gutjnl-2014-308398 |
0.316 |
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| 2015 |
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, ... ... van Duijn CM, et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry. 20: 647-56. PMID 25288136 DOI: 10.1038/Mp.2014.107 |
0.67 |
|
| 2015 |
van der Valk RJ, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, Myhre R, Huikari V, ... ... van Duijn CM, et al. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics. 24: 1155-68. PMID 25281659 DOI: 10.1093/Hmg/Ddu510 |
0.433 |
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| 2015 |
Vojinovic D, Adams HH, van der Lee SJ, Ibrahim-Verbaas CA, Brouwer R, van den Hout MC, Oole E, van Rooij J, Uitterlinden A, Hofman A, van IJcken WF, Aartsma-Rus A, van Ommen GB, Ikram MA, van Duijn CM, et al. The dystrophin gene and cognitive function in the general population. European Journal of Human Genetics : Ejhg. 23: 837-43. PMID 25227141 DOI: 10.1038/Ejhg.2014.183 |
0.422 |
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| 2015 |
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, ... ... van Duijn CM, et al. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 110-8. PMID 25199915 DOI: 10.1093/Gerona/Glu166 |
0.62 |
|
| 2015 |
Verwoert GC, Hofland J, Amin N, Mattace-Raso FU, Sijbrands EJ, Hofman A, van den Meiracker AH, Uitterlinden AG, van Duijn CM, de Jong FH, Danser AH. Expression and gene variation studies deny association of human HSD3B1 gene with aldosterone production or blood pressure. American Journal of Hypertension. 28: 113-20. PMID 24951726 DOI: 10.1093/Ajh/Hpu103 |
0.322 |
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| 2015 |
Versmissen J, Oosterveer DM, Yazdanpanah M, Dehghan A, Hólm H, Erdman J, Aulchenko YS, Thorleifsson G, Schunkert H, Huijgen R, Vongpromek R, Uitterlinden AG, Defesche JC, van Duijn CM, Mulder M, et al. Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach. European Journal of Human Genetics : Ejhg. 23: 381-7. PMID 24916650 DOI: 10.1038/Ejhg.2014.101 |
0.468 |
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| 2014 |
Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, ... ... van Duijn CM, et al. A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. Plos One. 10: e0123654. PMID 25918841 DOI: 10.1371/Journal.Pone.0123654 |
0.458 |
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| 2014 |
Kruithof CJ, Kooijman MN, van Duijn CM, Franco OH, de Jongste JC, Klaver CC, Mackenbach JP, Moll HA, Raat H, Rings EH, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, et al. The Generation R Study: Biobank update 2015. European Journal of Epidemiology. 29: 911-27. PMID 25527369 DOI: 10.1007/S10654-014-9980-6 |
0.461 |
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| 2014 |
van Leeuwen EM, Smouter FA, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, Bis JC, White CC, Jaiswal A, Oostra BA, Hofman A, ... ... van Duijn CM, et al. The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels. Plos One. 9: e109290. PMID 25329471 DOI: 10.1371/Journal.Pone.0109290 |
0.58 |
|
| 2014 |
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, ... ... van Duijn CM, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics. 46: 1173-86. PMID 25282103 DOI: 10.1038/Ng.3097 |
0.573 |
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| 2014 |
Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, ... ... van Duijn CM, et al. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nature Communications. 5: 4883. PMID 25241763 DOI: 10.1038/ncomms5883 |
0.579 |
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| 2014 |
Simpson CL, Wojciechowski R, Oexle K, Murgia F, Portas L, Li X, Verhoeven VJ, Vitart V, Schache M, Hosseini SM, Hysi PG, Raffel LJ, Cotch MF, Chew E, Klein BE, ... ... van Duijn CM, et al. Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. Plos One. 9: e107110. PMID 25233373 DOI: 10.1371/Journal.Pone.0107110 |
0.562 |
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| 2014 |
Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, ... ... van Duijn CM, et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 514: 92-7. PMID 25231870 DOI: 10.1038/Nature13545 |
0.581 |
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| 2014 |
Rietveld CA, Esko T, Davies G, Pers TH, Turley P, Benyamin B, Chabris CF, Emilsson V, Johnson AD, Lee JJ, de Leeuw C, Marioni RE, Medland SE, Miller MB, Rostapshova O, ... ... van Duijn CM, et al. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proceedings of the National Academy of Sciences of the United States of America. 111: 13790-4. PMID 25201988 DOI: 10.1073/Pnas.1404623111 |
0.479 |
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| 2014 |
Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, ... ... van Duijn CM, et al. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nature Genetics. 46: 1126-30. PMID 25173106 DOI: 10.1038/Ng.3087 |
0.608 |
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| 2014 |
Buitendijk GH, Amin N, Hofman A, van Duijn CM, Vingerling JR, Klaver CC. Direct-to-consumer personal genome testing for age-related macular degeneration. Investigative Ophthalmology & Visual Science. 55: 6167-74. PMID 25146986 DOI: 10.1167/Iovs.14-15142 |
0.332 |
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| 2014 |
Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, ... ... van Duijn CM, et al. Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics. 23: 6944-60. PMID 25096241 DOI: 10.1093/hmg/ddu401 |
0.461 |
|
| 2014 |
Broer L, Raschenberger J, Deelen J, Mangino M, Codd V, Pietiläinen KH, Albrecht E, Amin N, Beekman M, de Craen AJ, Gieger C, Haun M, Henneman P, Herder C, Hovatta I, ... ... van Duijn CM, et al. Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. European Journal of Epidemiology. 29: 629-38. PMID 25064619 DOI: 10.1007/s10654-014-9940-1 |
0.463 |
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| 2014 |
Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, ... ... van Duijn C, et al. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. American Journal of Human Genetics. 95: 49-65. PMID 24975945 DOI: 10.1016/J.Ajhg.2014.06.002 |
0.443 |
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| 2014 |
Bis JC, DeStefano A, Liu X, Brody JA, Choi SH, Verhaaren BF, Debette S, Ikram MA, Shahar E, Butler KR, Gottesman RF, Muzny D, Kovar CL, Psaty BM, Hofman A, ... ... van Duijn C, et al. Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium. Plos One. 9: e99798. PMID 24959832 DOI: 10.1371/Journal.Pone.0099798 |
0.396 |
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| 2014 |
Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, ... ... van Duijn CM, et al. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. American Journal of Human Genetics. 95: 24-38. PMID 24954895 DOI: 10.1016/J.Ajhg.2014.05.010 |
0.398 |
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| 2014 |
Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, ... ... van Duijn CM, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics. 46: 826-36. PMID 24952745 DOI: 10.1038/Ng.3014 |
0.553 |
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| 2014 |
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... van Duijn CM, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661 |
0.628 |
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| 2014 |
Adams HH, Verhaaren BF, Vrooman HA, Uitterlinden AG, Hofman A, van Duijn CM, van der Lugt A, Niessen WJ, Vernooij MW, Ikram MA. TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population. Biological Psychiatry. 76: 503-8. PMID 24731779 DOI: 10.1016/J.Biopsych.2014.03.006 |
0.335 |
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| 2014 |
Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, ... ... van Duijn CM, et al. Susceptibility to chronic mucus hypersecretion, a genome wide association study. Plos One. 9: e91621. PMID 24714607 DOI: 10.1371/Journal.Pone.0091621 |
0.345 |
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| 2014 |
Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, ... ... van Duijn CM, et al. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Human Molecular Genetics. 23: 4420-32. PMID 24688116 DOI: 10.1093/Hmg/Ddu139 |
0.574 |
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| 2014 |
Pirastu N, Kooyman M, Traglia M, Robino A, Willems SM, Pistis G, d'Adamo P, Amin N, d'Eustacchio A, Navarini L, Sala C, Karssen LC, van Duijn C, Toniolo D, Gasparini P. Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking. Plos One. 9: e92065. PMID 24647340 DOI: 10.1371/Journal.Pone.0092065 |
0.323 |
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| 2014 |
Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, ... ... van Duijn CM, et al. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics. 94: 349-60. PMID 24560520 DOI: 10.1016/J.Ajhg.2013.12.016 |
0.305 |
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| 2014 |
Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... van Duijn C, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897 |
0.473 |
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| 2014 |
Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, ... ... van Duijn CM, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. 94: 233-45. PMID 24507775 DOI: 10.1016/J.Ajhg.2014.01.010 |
0.391 |
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| 2014 |
Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, ... ... van Duijn CM, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. American Journal of Human Genetics. 94: 223-32. PMID 24507774 DOI: 10.1016/J.Ajhg.2014.01.009 |
0.354 |
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| 2014 |
Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, ... ... van Duijn CM, et al. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke; a Journal of Cerebral Circulation. 45: 403-12. PMID 24436238 DOI: 10.1161/Strokeaha.113.003044 |
0.306 |
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| 2014 |
Malik R, Bevan S, Nalls MA, Holliday EG, Devan WJ, Cheng YC, Ibrahim-Verbaas CA, Verhaaren BF, Bis JC, Joon AY, de Stefano AL, Fornage M, Psaty BM, Ikram MA, Launer LJ, ... van Duijn CM, et al. Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke; a Journal of Cerebral Circulation. 45: 394-402. PMID 24436234 DOI: 10.1161/Strokeaha.113.002938 |
0.302 |
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| 2014 |
Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, ... van Duijn CM, et al. Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. International Journal of Epidemiology. 43: 878-86. PMID 24425829 DOI: 10.1093/Ije/Dyt267 |
0.383 |
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| 2014 |
van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Møller E, Cáceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, ... ... van Duijn C, et al. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. The Journal of Allergy and Clinical Immunology. 134: 46-55. PMID 24315451 DOI: 10.1016/J.Jaci.2013.08.053 |
0.308 |
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| 2014 |
Albrecht E, Sillanpää E, Karrasch S, Alves AC, Codd V, Hovatta I, Buxton JL, Nelson CP, Broer L, Hägg S, Mangino M, Willemsen G, Surakka I, Ferreira MA, Amin N, ... ... van Duijn CM, et al. Telomere length in circulating leukocytes is associated with lung function and disease. The European Respiratory Journal. 43: 983-92. PMID 24311771 DOI: 10.1183/09031936.00046213 |
0.411 |
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| 2014 |
Wang JJ, Buitendijk GH, Rochtchina E, Lee KE, Klein BE, van Duijn CM, Flood VM, Meuer SM, Attia J, Myers C, Holliday EG, Tan AG, Smith WT, Iyengar SK, de Jong PT, et al. Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations. Ophthalmology. 121: 667-75. PMID 24290803 DOI: 10.1016/J.Ophtha.2013.10.017 |
0.416 |
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| 2014 |
Liu F, Hendriks AE, Ralf A, Boot AM, Benyi E, Sävendahl L, Oostra BA, van Duijn C, Hofman A, Rivadeneira F, Uitterlinden AG, Drop SL, Kayser M. Common DNA variants predict tall stature in Europeans. Human Genetics. 133: 587-97. PMID 24253421 DOI: 10.1007/S00439-013-1394-0 |
0.604 |
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| 2014 |
Iglesias AI, Springelkamp H, van der Linde H, Severijnen LA, Amin N, Oostra B, Kockx CE, van den Hout MC, van Ijcken WF, Hofman A, Uitterlinden AG, Verdijk RM, Klaver CC, Willemsen R, van Duijn CM. Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age. Human Molecular Genetics. 23: 1320-32. PMID 24150847 DOI: 10.1093/Hmg/Ddt522 |
0.561 |
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| 2014 |
Boomsma DI, Wijmenga C, Slagboom EP, Swertz MA, Karssen LC, Abdellaoui A, Ye K, Guryev V, Vermaat M, Van Dijk F, Francioli LC, Hottenga JJ, Laros JFJ, Li Q, Li Y, ... ... Van Duijn CM, et al. The Genome of the Netherlands: Design, and project goals European Journal of Human Genetics. 22: 221-227. PMID 23714750 DOI: 10.1038/Ejhg.2013.118 |
0.532 |
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| 2013 |
Dharuri H, Henneman P, Demirkan A, van Klinken JB, Mook-Kanamori DO, Wang-Sattler R, Gieger C, Adamski J, Hettne K, Roos M, Suhre K, Van Duijn CM, van Dijk KW, 't Hoen PA. Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles. Bmc Genomics. 14: 865. PMID 24320595 DOI: 10.1186/1471-2164-14-865 |
0.342 |
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| 2013 |
Hofman A, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2014 objectives and design update. European Journal of Epidemiology. 28: 889-926. PMID 24258680 DOI: 10.1007/s10654-013-9866-z |
0.435 |
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| 2013 |
Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, ... ... van Duijn CM, et al. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. American Journal of Human Genetics. 93: 264-77. PMID 24144296 DOI: 10.1016/J.Ajhg.2013.06.016 |
0.532 |
|
| 2013 |
Buitendijk GH, Rochtchina E, Myers C, van Duijn CM, Lee KE, Klein BE, Meuer SM, de Jong PT, Holliday EG, Tan AG, Uitterlinden AG, Sivakumaran TA, Sivakumaran TS, Attia J, Hofman A, et al. Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium. Ophthalmology. 120: 2644-55. PMID 24120328 DOI: 10.1016/J.Ophtha.2013.07.053 |
0.383 |
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| 2013 |
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, ... ... van Duijn CM, et al. Discovery and refinement of loci associated with lipid levels. Nature Genetics. 45: 1274-83. PMID 24097068 DOI: 10.1038/Ng.2797 |
0.398 |
|
| 2013 |
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, ... ... van Duijn CM, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics. 45: 1345-52. PMID 24097064 DOI: 10.1038/Ng.2795 |
0.355 |
|
| 2013 |
Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, ... ... van Duijn C, et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics. 45: 1353-60. PMID 24076602 DOI: 10.1038/Ng.2770 |
0.32 |
|
| 2013 |
Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, ... ... van Duijn CM, et al. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nature Genetics. 45: 1375-9. PMID 24036949 DOI: 10.1038/Ng.2758 |
0.381 |
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| 2013 |
Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, ... ... van Duijn CM, et al. Common variants in Mendelian kidney disease genes and their association with renal function. Journal of the American Society of Nephrology : Jasn. 24: 2105-17. PMID 24029420 DOI: 10.1681/Asn.2012100983 |
0.593 |
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| 2013 |
Ansari M, McKeigue PM, Skerka C, Hayward C, Rudan I, Vitart V, Polasek O, Armbrecht AM, Yates JR, Vatavuk Z, Bencic G, Kolcic I, Oostra BA, Van Duijn CM, Campbell S, et al. Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration. Human Molecular Genetics. 22: 4857-69. PMID 23873044 DOI: 10.1093/Hmg/Ddt336 |
0.455 |
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| 2013 |
Fall T, Hägg S, Mägi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, ... ... van Duijn CM, et al. The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. Plos Medicine. 10: e1001474. PMID 23824655 DOI: 10.1371/Journal.Pmed.1001474 |
0.55 |
|
| 2013 |
Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, ... ... van Duijn C, et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nature Genetics. 45: 912-7. PMID 23793025 DOI: 10.1038/Ng.2676 |
0.455 |
|
| 2013 |
Sim X, Jensen RA, Ikram MK, Cotch MF, Li X, MacGregor S, Xie J, Smith AV, Boerwinkle E, Mitchell P, Klein R, Klein BE, Glazer NL, Lumley T, McKnight B, ... ... van Duijn CM, et al. Genetic loci for retinal arteriolar microcirculation. Plos One. 8: e65804. PMID 23776548 DOI: 10.1371/Journal.Pone.0065804 |
0.461 |
|
| 2013 |
Isaacs A, Willems SM, Bos D, Dehghan A, Hofman A, Ikram MA, Uitterlinden AG, Oostra BA, Franco OH, Witteman JC, van Duijn CM. Risk scores of common genetic variants for lipid levels influence atherosclerosis and incident coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2233-9. PMID 23766260 DOI: 10.1161/Atvbaha.113.301236 |
0.504 |
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| 2013 |
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, ... ... van Duijn CM, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Plos Genetics. 9: e1003500. PMID 23754948 DOI: 10.1371/Journal.Pgen.1003500 |
0.548 |
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| 2013 |
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, ... ... van Duijn CM, et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (New York, N.Y.). 340: 1467-71. PMID 23722424 DOI: 10.1126/Science.1235488 |
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| 2013 |
Graff M, Ngwa JS, Workalemahu T, Homuth G, Schipf S, Teumer A, Völzke H, Wallaschofski H, Abecasis GR, Edward L, Francesco C, Sanna S, Scheet P, Schlessinger D, Sidore C, ... ... Van Duijn CM, et al. Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Human Molecular Genetics. 22: 3597-607. PMID 23669352 DOI: 10.1093/Hmg/Ddt205 |
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| 2013 |
van der Loos MJ, Rietveld CA, Eklund N, Koellinger PD, Rivadeneira F, Abecasis GR, Ankra-Badu GA, Baumeister SE, Benjamin DJ, Biffar R, Blankenberg S, Boomsma DI, Cesarini D, Cucca F, de Geus EJ, ... ... van Duijn CM, et al. The molecular genetic architecture of self-employment. Plos One. 8: e60542. PMID 23593239 DOI: 10.1371/Journal.Pone.0060542 |
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| 2013 |
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, ... ... van Duijn CM, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 45: 621-31. PMID 23583979 DOI: 10.1038/Ng.2610 |
0.506 |
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| 2013 |
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, ... ... van Duijn CM, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics. 45: 501-12. PMID 23563607 DOI: 10.1038/Ng.2606 |
0.558 |
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| 2013 |
Fernández-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, McArdle PF, Yerges-Armstrong LM, Elks CE, Strachan DP, Kutalik Z, ... ... van Duijn CM, et al. Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. American Journal of Epidemiology. 178: 451-60. PMID 23558354 DOI: 10.1093/Aje/Kws473 |
0.554 |
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| 2013 |
Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, ... ... van Duijn CM, et al. Identification of seven loci affecting mean telomere length and their association with disease. Nature Genetics. 45: 422-7, 427e1-2. PMID 23535734 DOI: 10.1038/Ng.2528 |
0.549 |
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| 2013 |
Stambolian D, Wojciechowski R, Oexle K, Pirastu M, Li X, Raffel LJ, Cotch MF, Chew EY, Klein B, Klein R, Wong TY, Simpson CL, Klaver CC, van Duijn CM, Verhoeven VJ, et al. Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. Human Molecular Genetics. 22: 2754-64. PMID 23474815 DOI: 10.1093/Hmg/Ddt116 |
0.613 |
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| 2013 |
Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, ... ... van Duijn CM, et al. Seven new loci associated with age-related macular degeneration. Nature Genetics. 45: 433-9, 439e1-2. PMID 23455636 DOI: 10.1038/Ng.2578 |
0.378 |
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| 2013 |
Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, ... ... van Duijn CM, et al. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nature Genetics. 45: 314-8. PMID 23396134 DOI: 10.1038/Ng.2554 |
0.582 |
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| 2013 |
Jensen RA, Sim X, Li X, Cotch MF, Ikram MK, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BE, Launer LJ, Smith AV, Boerwinkle E, Cheung N, Hewitt AW, ... ... van Duijn CM, et al. Genome-wide association study of retinopathy in individuals without diabetes. Plos One. 8: e54232. PMID 23393555 DOI: 10.1371/Journal.Pone.0054232 |
0.323 |
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| 2013 |
Holliday EG, Smith AV, Cornes BK, Buitendijk GH, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, Cheng CY, van Duijn CM, Eiriksdottir G, Gudnason V, Harris T, et al. Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. Plos One. 8: e53830. PMID 23326517 DOI: 10.1371/Journal.Pone.0053830 |
0.359 |
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| 2013 |
Lopes MC, Hysi PG, Verhoeven VJ, Macgregor S, Hewitt AW, Montgomery GW, Cumberland P, Vingerling JR, Young TL, van Duijn CM, Oostra B, Uitterlinden AG, Rahi JS, Mackey DA, Klaver CC, et al. Identification of a candidate gene for astigmatism. Investigative Ophthalmology & Visual Science. 54: 1260-7. PMID 23322567 DOI: 10.1167/Iovs.12-10463 |
0.543 |
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| 2013 |
Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJ, Henders A, Nelson CP, Steves CJ, Wright MJ, de Craen AJ, ... ... van Duijn CM, et al. Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. European Journal of Human Genetics : Ejhg. 21: 1163-8. PMID 23321625 DOI: 10.1038/Ejhg.2012.303 |
0.43 |
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| 2013 |
Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E, Kho A, Hayes MG, Ritchie MD, Saip A, Crawford DC, ... ... van Duijn CM, et al. Genetic variation associated with circulating monocyte count in the eMERGE Network. Human Molecular Genetics. 22: 2119-27. PMID 23314186 DOI: 10.1093/Hmg/Ddt010 |
0.347 |
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| 2013 |
Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, ... ... van Duijn CM, et al. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics. 22: 1663-78. PMID 23303523 DOI: 10.1093/Hmg/Dds555 |
0.355 |
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| 2013 |
Lu Y, Vitart V, Burdon KP, Khor CC, Bykhovskaya Y, Mirshahi A, Hewitt AW, Koehn D, Hysi PG, Ramdas WD, Zeller T, Vithana EN, Cornes BK, Tay WT, Tai ES, ... ... van Duijn CM, et al. Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nature Genetics. 45: 155-63. PMID 23291589 DOI: 10.1038/Ng.2506 |
0.337 |
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| 2013 |
Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, ... ... van Duijn CM, et al. A genome-wide association study of depressive symptoms. Biological Psychiatry. 73: 667-78. PMID 23290196 DOI: 10.1016/J.Biopsych.2012.09.033 |
0.608 |
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| 2013 |
Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, ... ... van Duijn CM, et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics. 45: 145-54. PMID 23263486 DOI: 10.1038/Ng.2500 |
0.405 |
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| 2013 |
Bos D, Ikram MA, Isaacs A, Verhaaren BF, Hofman A, van Duijn CM, Witteman JC, van der Lugt A, Vernooij MW. Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification. Circulation. Cardiovascular Genetics. 6: 47-53. PMID 23247144 DOI: 10.1161/Circgenetics.112.963934 |
0.35 |
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| 2013 |
Amin N, Hottenga JJ, Hansell NK, Janssens AC, de Moor MH, Madden PA, Zorkoltseva IV, Penninx BW, Terracciano A, Uda M, Tanaka T, Esko T, Realo A, Ferrucci L, Luciano M, ... ... van Duijn CM, et al. Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. European Journal of Human Genetics : Ejhg. 21: 876-82. PMID 23211697 DOI: 10.1038/Ejhg.2012.263 |
0.495 |
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| 2013 |
Demirkan A, Isaacs A, Ugocsai P, Liebisch G, Struchalin M, Rudan I, Wilson JF, Pramstaller PP, Gyllensten U, Campbell H, Schmitz G, Oostra BA, van Duijn CM. Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study. Journal of Psychiatric Research. 47: 357-62. PMID 23207112 DOI: 10.1016/j.jpsychires.2012.11.001 |
0.367 |
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| 2013 |
Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, ... ... van Duijn CM, et al. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics. 45: 76-82. PMID 23202124 DOI: 10.1038/Ng.2477 |
0.554 |
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| 2013 |
Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, ... ... van Duijn CM, et al. Variant of TREM2 associated with the risk of Alzheimer's disease. The New England Journal of Medicine. 368: 107-16. PMID 23150908 DOI: 10.1056/Nejmoa1211103 |
0.439 |
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| 2013 |
Stam AH, Weller CM, Janssens AC, Aulchenko YS, Oostra BA, Frants RR, van den Maagdenberg AM, Ferrari MD, van Duijn CM, Terwindt GM. Migraine is not associated with enhanced atherosclerosis. Cephalalgia : An International Journal of Headache. 33: 228-35. PMID 23147163 DOI: 10.1177/0333102412466966 |
0.437 |
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| 2013 |
Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, et al. Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiology of Aging. 34: 1309.e1-7. PMID 23036584 DOI: 10.1016/j.neurobiolaging.2012.08.010 |
0.535 |
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| 2013 |
Oosterveer DM, Versmissen J, Defesche JC, Sivapalaratnam S, Yazdanpanah M, Mulder M, van der Zee L, Uitterlinden AG, van Duijn CM, Hofman A, Kastelein JJ, Aulchenko YS, Sijbrands EJ. Low-density lipoprotein receptor mutations generate synthetic genome-wide associations. European Journal of Human Genetics : Ejhg. 21: 563-6. PMID 22968135 DOI: 10.1038/Ejhg.2012.207 |
0.468 |
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| 2013 |
Peters MJ, Broer L, Willemen HL, Eiriksdottir G, Hocking LJ, Holliday KL, Horan MA, Meulenbelt I, Neogi T, Popham M, Schmidt CO, Soni A, Valdes AM, Amin N, Dennison EM, ... ... van Duijn CM, et al. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Annals of the Rheumatic Diseases. 72: 427-36. PMID 22956598 DOI: 10.1136/Annrheumdis-2012-201742 |
0.565 |
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| 2013 |
Verhaaren BF, Vernooij MW, Koudstaal PJ, Uitterlinden AG, van Duijn CM, Hofman A, Breteler MM, Ikram MA. Alzheimer's disease genes and cognition in the nondemented general population. Biological Psychiatry. 73: 429-34. PMID 22592056 DOI: 10.1016/J.Biopsych.2012.04.009 |
0.586 |
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| 2013 |
Van Den Berg L, Henneman P, Willems Van Dijk K, Delemarre-Van De Waal HA, Oostra BA, Van Duijn CM, Janssens ACJW. Heritability of dietary food intake patterns Acta Diabetologica. 50: 721-726. PMID 22415036 DOI: 10.1007/s00592-012-0387-0 |
0.415 |
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| 2012 |
Jaddoe VW, van Duijn CM, Franco OH, van der Heijden AJ, van Iizendoorn MH, de Jongste JC, van der Lugt A, Mackenbach JP, Moll HA, Raat H, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, et al. The Generation R Study: design and cohort update 2012. European Journal of Epidemiology. 27: 739-56. PMID 23086283 DOI: 10.1007/s10654-012-9735-1 |
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| 2012 |
Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, ... ... van Duijn CM, et al. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. American Journal of Human Genetics. 91: 744-53. PMID 23022100 DOI: 10.1016/J.Ajhg.2012.08.021 |
0.423 |
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| 2012 |
Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, ... ... van Duijn CM, et al. FTO genotype is associated with phenotypic variability of body mass index. Nature. 490: 267-72. PMID 22982992 DOI: 10.1038/Nature11401 |
0.59 |
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| 2012 |
Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, ... ... van Duijn CM, et al. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Human Molecular Genetics. 21: 5329-43. PMID 22962313 DOI: 10.1093/Hmg/Dds369 |
0.573 |
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| 2012 |
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, ... ... van Duijn CM, et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics. 44: 991-1005. PMID 22885924 DOI: 10.1038/Ng.2385 |
0.594 |
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| 2012 |
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, ... ... van Duijn C, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics. 44: 981-90. PMID 22885922 DOI: 10.1038/Ng.2383 |
0.407 |
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| 2012 |
Ibrahim-Verbaas CA, Zorkoltseva IV, Amin N, Schuur M, Coppus AM, Isaacs A, Aulchenko YS, Breteler MM, Ikram MA, Axenovich TI, Verbeek MM, van Swieten JC, Oostra BA, van Duijn CM. Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2. Human Genetics. 131: 1869-76. PMID 22872014 DOI: 10.1007/S00439-012-1210-2 |
0.711 |
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| 2012 |
McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G, Kaakinen M, Lyytikäinen LP, Kristiansson K, Havulinna AS, Gögele M, Vitart V, Tenesa A, ... ... van Duijn CM, et al. Evidence of inbreeding depression on human height. Plos Genetics. 8: e1002655. PMID 22829771 DOI: 10.1371/Journal.Pgen.1002655 |
0.646 |
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| 2012 |
Durik M, Kavousi M, van der Pluijm I, Isaacs A, Cheng C, Verdonk K, Loot AE, Oeseburg H, Bhaggoe UM, Leijten F, van Veghel R, de Vries R, Rudez G, Brandt R, Ridwan YR, ... ... van Duijn CM, et al. Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation. 126: 468-78. PMID 22705887 DOI: 10.1161/Circulationaha.112.104380 |
0.46 |
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| 2012 |
Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, ... ... van Duijn CM, et al. Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology. 119: 1874-85. PMID 22705344 DOI: 10.1016/J.Ophtha.2012.03.014 |
0.359 |
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| 2012 |
Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, ... ... van Duijn C, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/Journal.Pgen.1002741 |
0.515 |
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| 2012 |
Freilinger T, Anttila V, de Vries B, Malik R, Kallela M, Terwindt GM, Pozo-Rosich P, Winsvold B, Nyholt DR, van Oosterhout WP, Artto V, Todt U, Hämäläinen E, Fernández-Morales J, Louter MA, ... ... van Duijn CM, et al. Genome-wide association analysis identifies susceptibility loci for migraine without aura. Nature Genetics. 44: 777-82. PMID 22683712 DOI: 10.1038/Ng.2307 |
0.438 |
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| 2012 |
Verhoeven VJ, Hysi PG, Saw SM, Vitart V, Mirshahi A, Guggenheim JA, Cotch MF, Yamashiro K, Baird PN, Mackey DA, Wojciechowski R, Ikram MK, Hewitt AW, Duggal P, Janmahasatian S, ... ... van Duijn CM, et al. Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Human Genetics. 131: 1467-80. PMID 22665138 DOI: 10.1007/S00439-012-1176-0 |
0.588 |
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| 2012 |
Rodenburg EM, Eijgelsheim M, Geleijnse JM, Amin N, van Duijn CM, Hofman A, Uitterlinden AG, Stricker BH, Visser LE. CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking. The American Journal of Clinical Nutrition. 96: 182-7. PMID 22648710 DOI: 10.3945/Ajcn.111.027102 |
0.356 |
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| 2012 |
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, ... ... van Duijn CM, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics. 44: 659-69. PMID 22581228 DOI: 10.1038/Ng.2274 |
0.538 |
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| 2012 |
van Koolwijk LM, Ramdas WD, Ikram MK, Jansonius NM, Pasutto F, Hysi PG, Macgregor S, Janssen SF, Hewitt AW, Viswanathan AC, ten Brink JB, Hosseini SM, Amin N, Despriet DD, Willemse-Assink JJ, ... ... van Duijn CM, et al. Common genetic determinants of intraocular pressure and primary open-angle glaucoma. Plos Genetics. 8: e1002611. PMID 22570627 DOI: 10.1371/Journal.Pgen.1002611 |
0.596 |
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| 2012 |
Baas DC, Ho L, Tanck MW, Fritsche LG, Merriam JE, van het Slot R, Koeleman BP, Gorgels TG, van Duijn CM, Uitterlinden AG, de Jong PT, Hofman A, ten Brink JB, Vingerling JR, Klaver CC, et al. Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. Molecular Vision. 18: 657-74. PMID 22509097 |
0.376 |
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| 2012 |
Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, ... ... van Duijn CM, et al. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nature Genetics. 44: 545-51. PMID 22504421 DOI: 10.1038/Ng.2237 |
0.748 |
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| 2012 |
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, ... ... van Duijn CM, et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics. 44: 491-501. PMID 22504420 DOI: 10.1038/Ng.2249 |
0.546 |
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| 2012 |
Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, ... ... van Duijn CM, et al. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics. 44: 532-8. PMID 22504419 DOI: 10.1038/Ng.2238 |
0.591 |
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| 2012 |
Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT, Niessen WJ, DeStefano AL, ... ... van Duijn CM, et al. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nature Genetics. 44: 539-44. PMID 22504418 DOI: 10.1038/Ng.2245 |
0.562 |
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| 2012 |
Ameur A, Enroth S, Johansson A, Zaboli G, Igl W, Johansson AC, Rivas MA, Daly MJ, Schmitz G, Hicks AA, Meitinger T, Feuk L, van Duijn C, Oostra B, Pramstaller PP, et al. Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids. American Journal of Human Genetics. 90: 809-20. PMID 22503634 DOI: 10.1016/J.Ajhg.2012.03.014 |
0.444 |
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| 2012 |
Heun R, Kölsch H, Ibrahim-Verbaas CA, Combarros O, Aulchenko YS, Breteler M, Schuur M, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Wilcock GK, Brown K, Barber R, Kehoe PG, et al. Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project. International Journal of Molecular Epidemiology and Genetics. 3: 39-47. PMID 22493750 |
0.441 |
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| 2012 |
Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PM, Zhao J, ... ... van Duijn CM, et al. A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics. 44: 526-31. PMID 22484627 DOI: 10.1038/Ng.2247 |
0.411 |
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| 2012 |
Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... van Duijn C, ... ... van Duijn CM, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607 |
0.566 |
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| 2012 |
Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, ... ... van Duijn CM, et al. Genome-wide association and functional follow-up reveals new loci for kidney function. Plos Genetics. 8: e1002584. PMID 22479191 DOI: 10.1371/Journal.Pgen.1002584 |
0.523 |
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| 2012 |
Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson Ã…, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, et al. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. Plos Genetics. 8: e1002490. PMID 22359512 DOI: 10.1371/Journal.Pgen.1002490 |
0.588 |
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| 2012 |
Stolk L, Perry JR, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, Byrne EM, Ernst F, Esko T, Franceschini N, Gudbjartsson DF, Hottenga JJ, Kraft P, ... ... van Duijn CM, et al. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nature Genetics. 44: 260-8. PMID 22267201 DOI: 10.1038/Ng.1051 |
0.554 |
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| 2012 |
Gasten AC, Ramdas WD, Broer L, van Koolwijk LME, Kamran Ikram M, de Jong PTVM, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CCW, Jansonius NM, ... ... van Duijn CM, et al. A genetic epidemiologic study of candidate genes involved in the optic nerve head morphology Investigative Ophthalmology and Visual Science. 53: 1485-1491. PMID 22266513 DOI: 10.1167/Iovs.11-7384 |
0.576 |
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| 2012 |
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, ... ... van Duijn CM, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202 |
0.614 |
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| 2012 |
Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, ... ... van Duijn CM, et al. Longevity candidate genes and their association with personality traits in the elderly. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 192-200. PMID 22213687 DOI: 10.1002/Ajmg.B.32013 |
0.501 |
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| 2012 |
Taal HR, Verwoert GC, Demirkan A, Janssens AC, Rice K, Ehret G, Smith AV, Verhaaren BF, Witteman JC, Hofman A, Vernooij MW, Uitterlinden AG, Rivadeneira F, Ikram MA, Levy D, ... ... van Duijn CM, et al. Genome-wide profiling of blood pressure in adults and children. Hypertension. 59: 241-7. PMID 22203742 DOI: 10.1161/Hypertensionaha.111.179481 |
0.383 |
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| 2012 |
Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, Lamina C, Schillert A, Coassin S, Bis JC, Broer L, Crawford DC, Franceschini N, Frikke-Schmidt R, Haun M, ... ... van Duijn CM, et al. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circulation. Cardiovascular Genetics. 5: 100-12. PMID 22199011 DOI: 10.1161/Circgenetics.111.961292 |
0.63 |
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| 2012 |
Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, ... ... van Duijn CM, et al. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nature Genetics. 44: 187-92. PMID 22197932 DOI: 10.1038/Ng.1017 |
0.487 |
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| 2012 |
Sanchez-Juan P, Bishop MT, Aulchenko YS, Brandel JP, Rivadeneira F, Struchalin M, Lambert JC, Amouyel P, Combarros O, Sainz J, Carracedo A, Uitterlinden AG, Hofman A, Zerr I, Kretzschmar HA, ... ... van Duijn CM, et al. Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. Neurobiology of Aging. 33: 1487.e21-8. PMID 22137330 DOI: 10.1016/J.Neurobiolaging.2011.10.011 |
0.47 |
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| 2012 |
Schrijvers EM, Schürmann B, Koudstaal PJ, van den Bussche H, Van Duijn CM, Hentschel F, Heun R, Hofman A, Jessen F, Kölsch H, Kornhuber J, Peters O, Rivadeneira F, Rüther E, Uitterlinden AG, et al. Genome-wide association study of vascular dementia. Stroke; a Journal of Cerebral Circulation. 43: 315-9. PMID 22116812 DOI: 10.1161/Strokeaha.111.628768 |
0.605 |
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| 2012 |
Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, ... ... van Duijn CM, et al. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circulation. Cardiovascular Genetics. 5: 81-90. PMID 22068335 DOI: 10.1161/Circgenetics.111.959817 |
0.602 |
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| 2012 |
Kölsch H, Lehmann DJ, Ibrahim-Verbaas CA, Combarros O, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Breteler M, Wilcock GK, Brown K, Kehoe PG, et al. Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 473-9. PMID 22065208 DOI: 10.1007/S00702-011-0732-4 |
0.489 |
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| 2012 |
Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, ... ... van Duijn CM, et al. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. European Heart Journal. 33: 238-51. PMID 22003152 DOI: 10.1093/Eurheartj/Ehr372 |
0.389 |
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| 2012 |
Zaboli G, Ameur A, Igl W, Johansson Ã…, Hayward C, Vitart V, Campbell S, Zgaga L, Polasek O, Schmitz G, van Duijn C, Oostra B, Pramstaller P, Hicks A, Meitinger T, et al. Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits. European Journal of Human Genetics : Ejhg. 20: 77-83. PMID 21811304 DOI: 10.1038/ejhg.2011.138 |
0.48 |
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| 2012 |
Lehmann DJ, Schuur M, Warden DR, Hammond N, Belbin O, Kölsch H, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Morris CM, Barker R, Coto E, Alvarez V, Deloukas P, ... ... van Duijn CM, et al. Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiology of Aging. 33: 202.e1-13. PMID 20817350 DOI: 10.1016/J.Neurobiolaging.2010.07.018 |
0.442 |
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| 2011 |
O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, et al. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation. 124: 2855-64. PMID 22144573 DOI: 10.1161/Circulationaha.110.974899 |
0.463 |
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| 2011 |
Broer L, Koudstaal PJ, Amin N, Rivadeneira F, Uitterlinden AG, Hofman A, Oostra BA, Breteler MM, Ikram MA, van Duijn CM. Association of heat shock proteins with Parkinson's disease. European Journal of Epidemiology. 26: 933-5. PMID 22120601 DOI: 10.1007/S10654-011-9635-9 |
0.657 |
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| 2011 |
Axenovich T, Zorkoltseva I, Belonogova N, van Koolwijk LM, van Koolwijk L, Borodin P, Kirichenko A, Babenko V, Ramdas WD, Ramdas W, Amin N, Despriet DD, Despriet D, Vingerling JR, Vingerling J, ... ... van Duijn CM, ... ... van Duijn C, et al. Linkage and association analyses of glaucoma related traits in a large pedigree from a Dutch genetically isolated population. Journal of Medical Genetics. 48: 802-9. PMID 22058429 DOI: 10.1136/jmedgenet-2011-100436 |
0.486 |
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| 2011 |
Surakka I, Isaacs A, Karssen LC, Laurila PP, Middelberg RP, Tikkanen E, Ried JS, Lamina C, Mangino M, Igl W, Hottenga JJ, Lagou V, van der Harst P, Mateo Leach I, Esko T, ... ... van Duijn CM, et al. A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. Plos Genetics. 7: e1002333. PMID 22028671 DOI: 10.1371/Journal.Pgen.1002333 |
0.607 |
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| 2011 |
Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, ... ... van Duijn CM, et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nature Genetics. 43: 1131-8. PMID 22001757 DOI: 10.1038/Ng.970 |
0.381 |
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| 2011 |
Coppus AM, Schuur M, Vergeer J, Janssens AC, Oostra BA, Verbeek MM, van Duijn CM. Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome. Neurobiology of Aging. 33: 1988-94. PMID 21958962 DOI: 10.1016/j.neurobiolaging.2011.08.007 |
0.412 |
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| 2011 |
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, ... ... van Duijn CM, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 478: 103-9. PMID 21909115 DOI: 10.1038/Nature10405 |
0.509 |
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| 2011 |
Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, ... ... van Duijn CM, et al. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics. 43: 1005-11. PMID 21909110 DOI: 10.1038/Ng.922 |
0.646 |
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| 2011 |
Janssens AC, Henneman L, Detmar SB, Khoury MJ, Steyerberg EW, Eijkemans MJ, Mushkudiani N, Oostra BA, van Duijn CM, Mackenbach JP. Accuracy of self-reported family history is strongly influenced by the accuracy of self-reported personal health status of relatives. Journal of Clinical Epidemiology. 65: 82-9. PMID 21889309 DOI: 10.1016/j.jclinepi.2011.05.003 |
0.341 |
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| 2011 |
Hofman A, van Duijn CM, Franco OH, Ikram MA, Janssen HL, Klaver CC, Kuipers EJ, Nijsten TE, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Witteman JC. The Rotterdam Study: 2012 objectives and design update. European Journal of Epidemiology. 26: 657-86. PMID 21877163 DOI: 10.1007/s10654-011-9610-5 |
0.435 |
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| 2011 |
Ramdas WD, van Koolwijk LM, Cree AJ, Janssens AC, Amin N, de Jong PT, Wolfs RC, Gibson J, Kirwan JF, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Ennis S, Lotery AJ, ... ... van Duijn CM, et al. Clinical implications of old and new genes for open-angle glaucoma. Ophthalmology. 118: 2389-97. PMID 21872936 DOI: 10.1016/J.Ophtha.2011.05.040 |
0.586 |
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| 2011 |
Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D, Sonestedt E, Ngwa JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS, Tanaka T, Hindy G, Saylor G, ... ... van Duijn CM, et al. Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes. 60: 2407-16. PMID 21810599 DOI: 10.2337/Db11-0176 |
0.338 |
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| 2011 |
Holmes MV, Newcombe P, Hubacek JA, Sofat R, Ricketts SL, Cooper J, Breteler MM, Bautista LE, Sharma P, Whittaker JC, Smeeth L, Fowkes FG, Algra A, Shmeleva V, Szolnoki Z, ... ... van Duijn C, et al. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Lancet. 378: 584-94. PMID 21803414 DOI: 10.1016/S0140-6736(11)60872-6 |
0.459 |
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| 2011 |
Kuningas M, McQuillan R, Wilson JF, Hofman A, van Duijn CM, Uitterlinden AG, Tiemeier H. Runs of homozygosity do not influence survival to old age. Plos One. 6: e22580. PMID 21799906 DOI: 10.1371/Journal.Pone.0022580 |
0.537 |
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| 2011 |
Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, ... ... van Duijn C, et al. A genome-wide association study of aging. Neurobiology of Aging. 32: 2109.e15-28. PMID 21782286 DOI: 10.1016/J.Neurobiolaging.2011.05.026 |
0.578 |
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| 2011 |
Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, ... ... van Duijn CM, et al. Multiple loci are associated with white blood cell phenotypes. Plos Genetics. 7: e1002113. PMID 21738480 DOI: 10.1371/Journal.Pgen.1002113 |
0.585 |
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| 2011 |
Kilpeläinen TO, Zillikens MC, StanÄákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, ... ... van Duijn CM, et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics. 43: 753-60. PMID 21706003 DOI: 10.1038/Ng.866 |
0.569 |
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| 2011 |
Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, ... ... van Duijn CM, et al. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Annals of Neurology. 69: 928-39. PMID 21681796 DOI: 10.1002/Ana.22403 |
0.613 |
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| 2011 |
Ho L, van Leeuwen R, Witteman JC, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Vingerling JR, Klaver CC. Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ω-3 fatty acids: the Rotterdam study. Archives of Ophthalmology (Chicago, Ill. : 1960). 129: 758-66. PMID 21670343 DOI: 10.1001/Archophthalmol.2011.141 |
0.352 |
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| 2011 |
Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, ... ... van Duijn CM, et al. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Human Molecular Genetics. 20: 3699-709. PMID 21665990 DOI: 10.1093/Hmg/Ddr270 |
0.346 |
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| 2011 |
Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, ... ... van Duijn CM, et al. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 70: 252-65. PMID 21521612 DOI: 10.1016/J.Neuron.2011.04.005 |
0.52 |
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| 2011 |
Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, ... ... van Duijn CM, et al. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America. 108: 7119-24. PMID 21471458 DOI: 10.1073/Pnas.1017288108 |
0.532 |
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| 2011 |
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... van Duijn CM, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/Ng.803 |
0.667 |
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| 2011 |
Ligthart L, de Vries B, Smith AV, Ikram MA, Amin N, Hottenga JJ, Koelewijn SC, Kattenberg VM, de Moor MH, Janssens AC, Aulchenko YS, Oostra BA, de Geus EJ, Smit JH, Zitman FG, ... ... van Duijn CM, et al. Meta-analysis of genome-wide association for migraine in six population-based European cohorts. European Journal of Human Genetics : Ejhg. 19: 901-7. PMID 21448238 DOI: 10.1038/Ejhg.2011.48 |
0.701 |
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| 2011 |
Demirkan A, Amin N, Isaacs A, Jarvelin MR, Whitfield JB, Wichmann HE, Kyvik KO, Rudan I, Gieger C, Hicks AA, Johansson Å, Hottenga JJ, Smith JJ, Wild SH, Pedersen NL, ... ... van Duijn CM, et al. Genetic architecture of circulating lipid levels. European Journal of Human Genetics : Ejhg. 19: 813-9. PMID 21448234 DOI: 10.1038/Ejhg.2011.21 |
0.551 |
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| 2011 |
Ramdas WD, van Koolwijk LM, Lemij HG, Pasutto F, Cree AJ, Thorleifsson G, Janssen SF, Jacoline TB, Amin N, Rivadeneira F, Wolfs RC, Walters GB, Jonasson F, Weisschuh N, Mardin CY, ... ... van Duijn CM, et al. Common genetic variants associated with open-angle glaucoma. Human Molecular Genetics. 20: 2464-71. PMID 21427129 DOI: 10.1093/Hmg/Ddr120 |
0.562 |
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| 2011 |
Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, ... ... van Duijn CM, et al. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell. 10: 686-98. PMID 21418511 DOI: 10.1111/j.1474-9726.2011.00705.x |
0.528 |
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| 2011 |
Broer L, Ikram MA, Schuur M, DeStefano AL, Bis JC, Liu F, Rivadeneira F, Uitterlinden AG, Beiser AS, Longstreth WT, Hofman A, Aulchenko Y, Seshadri S, Fitzpatrick AL, Oostra BA, ... ... van Duijn CM, et al. Association of HSP70 and its co-chaperones with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 93-102. PMID 21403392 DOI: 10.3233/Jad-2011-101560 |
0.687 |
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| 2011 |
Velders FP, Kuningas M, Kumari M, Dekker MJ, Uitterlinden AG, Kirschbaum C, Hek K, Hofman A, Verhulst FC, Kivimaki M, Van Duijn CM, Walker BR, Tiemeier H. Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology. 36: 1053-61. PMID 21316860 DOI: 10.1016/J.Psyneuen.2011.01.003 |
0.547 |
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| 2011 |
Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, ... ... van Duijn CM, et al. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 123: 731-8. PMID 21300955 DOI: 10.1161/Circulationaha.110.948570 |
0.488 |
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| 2011 |
Ramdas WD, Amin N, van Koolwijk LM, Janssens AC, Demirkan A, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CC, Vingerling JR, ... ... van Duijn CM, et al. Genetic architecture of open angle glaucoma and related determinants. Journal of Medical Genetics. 48: 190-6. PMID 21059592 DOI: 10.1136/Jmg.2010.083337 |
0.599 |
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| 2010 |
Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, ... ... van Duijn CM, et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics. 42: 1077-85. PMID 21102462 DOI: 10.1038/Ng.714 |
0.581 |
|
| 2010 |
Sotoodehnia N, Isaacs A, de Bakker PI, Dörr M, Newton-Cheh C, Nolte IM, van der Harst P, Müller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, ... ... van Duijn CM, et al. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nature Genetics. 42: 1068-76. PMID 21076409 DOI: 10.1038/Ng.716 |
0.55 |
|
| 2010 |
Baas DC, Despriet DD, Gorgels TG, Bergeron-Sawitzke J, Uitterlinden AG, Hofman A, van Duijn CM, Merriam JE, Smith RT, Barile GR, ten Brink JB, Vingerling JR, Klaver CC, Allikmets R, Dean M, et al. The ERCC6 gene and age-related macular degeneration. Plos One. 5: e13786. PMID 21072178 DOI: 10.1371/Journal.Pone.0013786 |
0.443 |
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| 2010 |
Combarros O, Warden DR, Hammond N, Cortina-Borja M, Belbin O, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Gwilliam R, Heun R, ... ... van Duijn CM, et al. The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project. Bmc Medical Genetics. 11: 162. PMID 21070631 DOI: 10.1186/1471-2350-11-162 |
0.509 |
|
| 2010 |
Ikram MK, Sim X, Xueling S, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, Wang JJ, Klein R, Klein BE, Breteler MM, Cheung N, Liew G, Mitchell P, Uitterlinden AG, ... ... van Duijn CM, et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. Plos Genetics. 6: e1001184. PMID 21060863 DOI: 10.1371/Journal.Pgen.1001184 |
0.601 |
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| 2010 |
van Schie MC, de Maat MP, Isaacs A, van Duijn CM, Deckers JW, Dippel DW, Leebeek FW. Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease. Blood. 117: 1393-9. PMID 20940418 DOI: 10.1182/blood-2010-03-273961 |
0.329 |
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| 2010 |
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, ... ... van Duijn CM, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature Genetics. 42: 937-48. PMID 20935630 DOI: 10.1038/Ng.686 |
0.566 |
|
| 2010 |
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, ... ... van Duijn CM, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics. 42: 949-60. PMID 20935629 DOI: 10.1038/Ng.685 |
0.564 |
|
| 2010 |
Yang Q, Köttgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, ... ... van Duijn CM, et al. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circulation. Cardiovascular Genetics. 3: 523-30. PMID 20884846 DOI: 10.1161/Circgenetics.109.934455 |
0.393 |
|
| 2010 |
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, ... ... van Duijn CM, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467: 832-8. PMID 20881960 DOI: 10.1038/Nature09410 |
0.614 |
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| 2010 |
Solouki AM, Verhoeven VJ, van Duijn CM, Verkerk AJ, Ikram MK, Hysi PG, Despriet DD, van Koolwijk LM, Ho L, Ramdas WD, Czudowska M, Kuijpers RW, Amin N, Struchalin M, Aulchenko YS, et al. A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nature Genetics. 42: 897-901. PMID 20835239 DOI: 10.1038/Ng.663 |
0.595 |
|
| 2010 |
Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM, Calafato MS, Nyholt DR, Dimas AS, Freilinger T, Müller-Myhsok B, Artto V, Inouye M, Alakurtti K, Kaunisto MA, Hämäläinen E, ... ... van Duijn CM, et al. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nature Genetics. 42: 869-73. PMID 20802479 DOI: 10.1038/Ng.652 |
0.625 |
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| 2010 |
Meyer TE, Verwoert GC, Hwang SJ, Glazer NL, Smith AV, van Rooij FJ, Ehret GB, Boerwinkle E, Felix JF, Leak TS, Harris TB, Yang Q, Dehghan A, Aspelund T, Katz R, ... ... van Duijn CM, et al. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. Plos Genetics. 6. PMID 20700443 DOI: 10.1371/Journal.Pgen.1001045 |
0.44 |
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| 2010 |
Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J, van Rooij FJ, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T, Garcia M, Anderson JS, Follis JL, Djousse L, ... ... van Duijn CM, et al. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care. 33: 2684-91. PMID 20693352 DOI: 10.2337/Dc10-1150 |
0.316 |
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| 2010 |
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, ... ... van Duijn CM, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 466: 707-13. PMID 20686565 DOI: 10.1038/Nature09270 |
0.551 |
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| 2010 |
Vergeer M, Boekholdt SM, Sandhu MS, Ricketts SL, Wareham NJ, Brown MJ, de Faire U, Leander K, Gigante B, Kavousi M, Hofman A, Uitterlinden AG, van Duijn CM, Witteman JC, Jukema JW, et al. Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation. 122: 470-7. PMID 20644014 DOI: 10.1161/Circulationaha.109.912519 |
0.379 |
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| 2010 |
Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, de Bakker PI, Müller M, Morrison AC, Smith AV, Isaacs A, Sanna S, Dörr M, Navarro P, Fuchsberger C, Nolte IM, de Geus EJ, Estrada K, ... ... van Duijn CM, et al. Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics. 19: 3885-94. PMID 20639392 DOI: 10.1093/Hmg/Ddq303 |
0.571 |
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| 2010 |
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, ... ... van Duijn CM, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics. 42: 579-89. PMID 20581827 DOI: 10.1038/Ng.609 |
0.397 |
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| 2010 |
Mihaescu R, van Zitteren M, van Hoek M, Sijbrands EJ, Uitterlinden AG, Witteman JC, Hofman A, Hunink MG, van Duijn CM, Janssens AC. Improvement of risk prediction by genomic profiling: reclassification measures versus the area under the receiver operating characteristic curve. American Journal of Epidemiology. 172: 353-61. PMID 20562194 DOI: 10.1093/Aje/Kwq122 |
0.309 |
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| 2010 |
Kestenbaum B, Glazer NL, Köttgen A, Felix JF, Hwang SJ, Liu Y, Lohman K, Kritchevsky SB, Hausman DB, Petersen AK, Gieger C, Ried JS, Meitinger T, Strom TM, Wichmann HE, ... ... van Duijn CM, et al. Common genetic variants associate with serum phosphorus concentration. Journal of the American Society of Nephrology : Jasn. 21: 1223-32. PMID 20558539 DOI: 10.1681/Asn.2009111104 |
0.448 |
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| 2010 |
Ramdas WD, van Koolwijk LM, Ikram MK, Jansonius NM, de Jong PT, Bergen AA, Isaacs A, Amin N, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Hysi P, ... ... van Duijn CM, et al. A genome-wide association study of optic disc parameters. Plos Genetics. 6: e1000978. PMID 20548946 DOI: 10.1371/Journal.Pgen.1000978 |
0.578 |
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| 2010 |
Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT, ... ... van Duijn CM, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. Jama. 303: 1832-40. PMID 20460622 DOI: 10.1001/Jama.2010.574 |
0.625 |
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| 2010 |
Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples LA, Dehghan A, Lumley T, Rosamond WD, Lieb W, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, ... ... van Duijn CM, et al. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circulation. Cardiovascular Genetics. 3: 256-66. PMID 20445134 DOI: 10.1161/Circgenetics.109.895763 |
0.447 |
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| 2010 |
Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Mägi R, ... ... van Duijn CM, et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nature Genetics. 42: 448-53. PMID 20418888 DOI: 10.1038/Ng.573 |
0.626 |
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| 2010 |
Morrison AC, Felix JF, Cupples LA, Glazer NL, Loehr LR, Dehghan A, Demissie S, Bis JC, Rosamond WD, Aulchenko YS, Wang YA, Haritunians T, Folsom AR, Rivadeneira F, Benjamin EJ, ... ... van Duijn CM, et al. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circulation. Cardiovascular Genetics. 3: 248-55. PMID 20400778 DOI: 10.1161/Circgenetics.109.895995 |
0.434 |
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| 2010 |
Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, ... ... van Duijn CM, et al. New loci associated with kidney function and chronic kidney disease. Nature Genetics. 42: 376-84. PMID 20383146 DOI: 10.1038/Ng.568 |
0.526 |
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| 2010 |
Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Lange LA, Bradfield JP, Kerkhof M, Marsh JA, Mägi R, ... ... van Duijn CM, et al. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics. 42: 430-5. PMID 20372150 DOI: 10.1038/Ng.567 |
0.38 |
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| 2010 |
Yasuno K, Bilguvar K, Bijlenga P, Low SK, Krischek B, Auburger G, Simon M, Krex D, Arlier Z, Nayak N, Ruigrok YM, Niemelä M, Tajima A, von und zu Fraunberg M, Dóczi T, ... ... van Duijn CM, et al. Genome-wide association study of intracranial aneurysm identifies three new risk loci. Nature Genetics. 42: 420-5. PMID 20364137 DOI: 10.1038/Ng.563 |
0.521 |
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| 2010 |
Zillikens MC, van Meurs JB, Rivadeneira F, Hofman A, Oostra BA, Sijbrands EJ, Witteman JC, Pols HA, van Duijn CM, Uitterlinden AG. Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index. The American Journal of Clinical Nutrition. 91: 1387-93. PMID 20335544 DOI: 10.3945/Ajcn.2009.28627 |
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| 2010 |
Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB, Fitzpatrick AL, Franceschini N, Glazer NL, ... ... van Duijn CM, et al. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 478-87. PMID 20304771 DOI: 10.1093/Gerona/Glq028 |
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| 2010 |
Aulchenko YS, Struchalin MV, van Duijn CM. ProbABEL package for genome-wide association analysis of imputed data. Bmc Bioinformatics. 11: 134. PMID 20233392 DOI: 10.1186/1471-2105-11-134 |
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| 2010 |
Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, ... ... Van Duijn CM, et al. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 121: 1382-92. PMID 20231535 DOI: 10.1161/Circulationaha.109.869156 |
0.429 |
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| 2010 |
Pattaro C, De Grandi A, Vitart V, Hayward C, Franke A, Aulchenko YS, Johansson A, Wild SH, Melville SA, Isaacs A, Polasek O, Ellinghaus D, Kolcic I, Nöthlings U, Zgaga L, ... ... van Duijn CM, et al. A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. Bmc Medical Genetics. 11: 41. PMID 20222955 DOI: 10.1186/1471-2350-11-41 |
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| 2010 |
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... van Duijn CM, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/Ng.520 |
0.519 |
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| 2010 |
Henneman P, Aulchenko YS, Frants RR, Zorkoltseva IV, Zillikens MC, Frolich M, Oostra BA, van Dijk KW, van Duijn CM. Genetic architecture of plasma adiponectin overlaps with the genetics of metabolic syndrome-related traits. Diabetes Care. 33: 908-13. PMID 20067957 DOI: 10.2337/Dc09-1385 |
0.44 |
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| 2010 |
Igl W, Johansson A, Wilson JF, Wild SH, Polasek O, Hayward C, Vitart V, Hastie N, Rudan P, Gnewuch C, Schmitz G, Meitinger T, Pramstaller PP, Hicks AA, Oostra BA, ... van Duijn CM, et al. Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels. Plos Genetics. 6: e1000798. PMID 20066028 DOI: 10.1371/journal.pgen.1000798 |
0.543 |
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| 2010 |
Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, ... ... van Duijn CM, et al. Genome-wide association study of PR interval. Nature Genetics. 42: 153-9. PMID 20062060 DOI: 10.1038/Ng.517 |
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| 2010 |
Pecioska S, Zillikens MC, Henneman P, Snijders PJ, Oostra BA, van Duijn CM, Aulchenko YS. Association between type 2 diabetes loci and measures of fatness. Plos One. 5: e8541. PMID 20049090 DOI: 10.1371/journal.pone.0008541 |
0.404 |
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| 2010 |
Debette S, Bis JC, Fornage M, Schmidt H, Ikram MA, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, DeCarli C, Lumley T, Knopman DS, Enzinger C, Eiriksdottir G, ... ... van Duijn CM, et al. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke; a Journal of Cerebral Circulation. 41: 210-7. PMID 20044523 DOI: 10.1161/Strokeaha.109.569194 |
0.62 |
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| 2010 |
Baas DC, Ho L, Ennis S, Merriam JE, Tanck MW, Uitterlinden AG, de Jong PT, Cree AJ, Griffiths HL, Rivadeneira F, Hofman A, van Duijn C, Smith RT, Barile GR, Gorgels TG, et al. The complement component 5 gene and age-related macular degeneration. Ophthalmology. 117: 500-11. PMID 20022638 DOI: 10.1016/J.Ophtha.2009.08.032 |
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| 2010 |
Heid IM, Henneman P, Hicks A, Coassin S, Winkler T, Aulchenko YS, Fuchsberger C, Song K, Hivert MF, Waterworth DM, Timpson NJ, Richards JB, Perry JR, Tanaka T, Amin N, ... ... van Duijn CM, et al. Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis. 208: 412-20. PMID 20018283 DOI: 10.1016/J.Atherosclerosis.2009.11.035 |
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| 2010 |
Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nature Genetics. 42: 45-52. PMID 20010835 DOI: 10.1038/Ng.500 |
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| 2010 |
Zillikens MC, Uitterlinden AG, van Leeuwen JP, Berends AL, Henneman P, van Dijk KW, Oostra BA, van Duijn CM, Pols HA, Rivadeneira F. The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density. Calcified Tissue International. 86: 116-25. PMID 19957167 DOI: 10.1007/s00223-009-9319-6 |
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| 2010 |
Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Floyd J, Hastie N, Knott S, Lauc G, ... ... van Duijn CM, et al. Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. Obesity (Silver Spring, Md.). 18: 803-8. PMID 19851299 DOI: 10.1038/oby.2009.359 |
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| 2010 |
Kovacs GG, Sanchez-Juan P, Ströbel T, Schuur M, Poleggi A, Nocentini S, Giannattasio C, Belay G, Bishop M, Capellari S, Parchi P, Gelpi E, Gal A, Bakos A, Molnar MJ, ... ... van Duijn C, et al. Cathepsin D (C224T) polymorphism in sporadic and genetic Creutzfeldt-Jakob disease. Alzheimer Disease and Associated Disorders. 24: 104-7. PMID 19571726 DOI: 10.1097/Wad.0B013E3181Ad378C |
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| 2010 |
Liu F, Pardo LM, Schuur M, Sanchez-Juan P, Isaacs A, Sleegers K, de Koning I, Zorkoltseva IV, Axenovich TI, Witteman JC, Janssens AC, van Swieten JC, Aulchenko YS, Oostra BA, van Duijn CM. The apolipoprotein E gene and its age-specific effects on cognitive function. Neurobiology of Aging. 31: 1831-3. PMID 19004527 DOI: 10.1016/j.neurobiolaging.2008.09.015 |
0.681 |
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| 2009 |
Marroni F, Pfeufer A, Aulchenko YS, Franklin CS, Isaacs A, Pichler I, Wild SH, Oostra BA, Wright AF, Campbell H, Witteman JC, Kääb S, Hicks AA, Gyllensten U, Rudan I, ... ... van Duijn CM, et al. A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. Circulation. Cardiovascular Genetics. 2: 322-8. PMID 20031603 DOI: 10.1161/Circgenetics.108.833806 |
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| 2009 |
Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, ... ... van Duijn CM, et al. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circulation. Cardiovascular Genetics. 2: 125-33. PMID 20031576 DOI: 10.1161/Circgenetics.108.825224 |
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| 2009 |
Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, ... ... Van Duijn CM, et al. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. Plos Genetics. 5: e1000768. PMID 20011104 DOI: 10.1371/Journal.Pgen.1000768 |
0.358 |
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| 2009 |
Ganesh SK, Zakai NA, van Rooij FJ, Soranzo N, Smith AV, Nalls MA, Chen MH, Kottgen A, Glazer NL, Dehghan A, Kuhnel B, Aspelund T, Yang Q, Tanaka T, Jaffe A, ... ... van Duijn CM, et al. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nature Genetics. 41: 1191-8. PMID 19862010 DOI: 10.1038/Ng.466 |
0.587 |
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| 2009 |
Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, ... ... van Duijn CM, et al. Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Annals of Internal Medicine. 151: 528-37. PMID 19841454 DOI: 10.7326/0003-4819-151-8-200910200-00006 |
0.57 |
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| 2009 |
Hoppenbrouwers IA, Aulchenko YS, Janssens AC, Ramagopalan SV, Broer L, Kayser M, Ebers GC, Oostra BA, Van Duijn CM, Hintzen RQ. Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis Journal of Human Genetics. 54: 676-680. PMID 19834503 DOI: 10.1038/jhg.2009.96 |
0.526 |
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| 2009 |
Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, ... ... van Duijn CM, et al. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nature Genetics. 41: 1199-206. PMID 19801982 DOI: 10.1038/Ng.446 |
0.535 |
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| 2009 |
Hicks AA, Pramstaller PP, Johansson A, Vitart V, Rudan I, Ugocsai P, Aulchenko Y, Franklin CS, Liebisch G, Erdmann J, Jonasson I, Zorkoltseva IV, Pattaro C, Hayward C, Isaacs A, ... ... van Duijn CM, et al. Genetic determinants of circulating sphingolipid concentrations in European populations. Plos Genetics. 5: e1000672. PMID 19798445 DOI: 10.1371/journal.pgen.1000672 |
0.553 |
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| 2009 |
Zillikens MC, van Meurs JB, Rivadeneira F, Amin N, Hofman A, Oostra BA, Sijbrands EJ, Witteman JC, Pols HA, van Duijn CM, Uitterlinden AG. SIRT1 genetic variation is related to BMI and risk of obesity. Diabetes. 58: 2828-34. PMID 19741164 DOI: 10.2337/Db09-0536 |
0.561 |
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| 2009 |
Hofman A, Breteler MM, van Duijn CM, Janssen HL, Krestin GP, Kuipers EJ, Stricker BH, Tiemeier H, Uitterlinden AG, Vingerling JR, Witteman JC. The Rotterdam Study: 2010 objectives and design update. European Journal of Epidemiology. 24: 553-72. PMID 19728115 DOI: 10.1007/S10654-009-9386-Z |
0.564 |
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| 2009 |
Amin N, van Duijn CM, Janssens AC. Genetic scoring analysis: a way forward in genome wide association studies? European Journal of Epidemiology. 24: 585-7. PMID 19728114 DOI: 10.1007/s10654-009-9387-y |
0.313 |
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| 2009 |
López-León S, Aulchenko YS, Tiemeier H, Oostra BA, van Duijn CM, Janssens AC. Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors. Journal of Affective Disorders. 122: 247-52. PMID 19674795 DOI: 10.1016/j.jad.2009.07.008 |
0.517 |
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| 2009 |
Mihaescu R, van Hoek M, Sijbrands EJ, Uitterlinden AG, Witteman JC, Hofman A, van Duijn CM, Janssens AC. Evaluation of risk prediction updates from commercial genome-wide scans. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 588-94. PMID 19636253 DOI: 10.1097/Gim.0B013E3181B13A4F |
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| 2009 |
Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB, Lumley T, Ehret GB, ... ... van Duijn CM, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nature Genetics. 41: 879-81. PMID 19597492 DOI: 10.1038/Ng.416 |
0.387 |
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| 2009 |
Liu F, Ikram MA, Janssens AC, Schuur M, de Koning I, Isaacs A, Struchalin M, Uitterlinden AG, den Dunnen JT, Sleegers K, Bettens K, Van Broeckhoven C, van Swieten J, Hofman A, Oostra BA, ... ... van Duijn CM, et al. A study of the SORL1 gene in Alzheimer's disease and cognitive function. Journal of Alzheimer's Disease : Jad. 18: 51-64. PMID 19584446 DOI: 10.3233/Jad-2009-1137 |
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| 2009 |
Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, ... ... van Duijn CM, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Jama. 302: 168-78. PMID 19584346 DOI: 10.1001/Jama.2009.978-A |
0.395 |
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| 2009 |
Estrada K, Krawczak M, Schreiber S, van Duijn K, Stolk L, van Meurs JB, Liu F, Penninx BW, Smit JH, Vogelzangs N, Hottenga JJ, Willemsen G, de Geus EJ, Lorentzon M, von Eller-Eberstein H, ... ... van Duijn CM, et al. A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Human Molecular Genetics. 18: 3516-24. PMID 19570815 DOI: 10.1093/Hmg/Ddp296 |
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| 2009 |
Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, ... ... van Duijn CM, et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. Plos Genetics. 5: e1000539. PMID 19557197 DOI: 10.1371/Journal.Pgen.1000539 |
0.594 |
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| 2009 |
Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, ... ... van Duijn CM, et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. Plos Genetics. 5: e1000508. PMID 19557161 DOI: 10.1371/Journal.Pgen.1000508 |
0.556 |
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| 2009 |
Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, ... ... van Duijn CM, et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nature Genetics. 41: 712-7. PMID 19430482 DOI: 10.1038/Ng.377 |
0.37 |
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| 2009 |
Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, ... ... van Duijn CM, et al. Genome-wide association study of blood pressure and hypertension. Nature Genetics. 41: 677-87. PMID 19430479 DOI: 10.1038/Ng.384 |
0.374 |
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| 2009 |
van Koolwijk LM, Despriet DD, Van Duijn CM, Oostra BA, van Swieten JC, de Koning I, Klaver CC, Lemij HG. Association of cognitive functioning with retinal nerve fiber layer thickness. Investigative Ophthalmology & Visual Science. 50: 4576-80. PMID 19420335 DOI: 10.1167/iovs.08-3181 |
0.538 |
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| 2009 |
Johnson AD, Kavousi M, Smith AV, Chen MH, Dehghan A, Aspelund T, Lin JP, van Duijn CM, Harris TB, Cupples LA, Uitterlinden AG, Launer L, Hofman A, Rivadeneira F, Stricker B, et al. Genome-wide association meta-analysis for total serum bilirubin levels. Human Molecular Genetics. 18: 2700-10. PMID 19414484 DOI: 10.1093/Hmg/Ddp202 |
0.499 |
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| 2009 |
Sie MP, Isaacs A, de Maat MP, Mattace-Raso FU, Uitterlinden AG, Kardys I, Hofman A, Hoeks AP, Reneman RS, van Duijn CM, Witteman JC. Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study. Journal of Hypertension. 27: 1392-8. PMID 19412134 DOI: 10.1097/Hjh.0B013E32832A95B0 |
0.313 |
|
| 2009 |
Pattaro C, Aulchenko YS, Isaacs A, Vitart V, Hayward C, Franklin CS, Polasek O, Kolcic I, Biloglav Z, Campbell S, Hastie N, Lauc G, Meitinger T, Oostra BA, Gyllensten U, ... ... van Duijn CM, et al. Genome-wide linkage analysis of serum creatinine in three isolated European populations. Kidney International. 76: 297-306. PMID 19387472 DOI: 10.1038/ki.2009.135 |
0.515 |
|
| 2009 |
Ikram MA, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, ... ... van Duijn CM, et al. Genomewide association studies of stroke. The New England Journal of Medicine. 360: 1718-28. PMID 19369658 DOI: 10.1056/Nejmoa0900094 |
0.613 |
|
| 2009 |
Janssens AC, González-Zuloeta Ladd AM, López-Léon S, Ioannidis JP, Oostra BA, Khoury MJ, van Duijn CM. An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 153-62. PMID 19367188 DOI: 10.1097/GIM.0b013e3181929237 |
0.516 |
|
| 2009 |
López-León S, Choy WC, Aulchenko YS, Claes SJ, Oostra BA, Mackenbach JP, van Duijn CM, Janssens AC. Genetic factors influence the clustering of depression among individuals with lower socioeconomic status. Plos One. 4: e5069. PMID 19333388 DOI: 10.1371/journal.pone.0005069 |
0.4 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement. European Journal of Clinical Investigation. 39: 247-66. PMID 19297801 DOI: 10.1111/J.1365-2362.2009.02125.X |
0.318 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. STrengthening the REporting of Genetic Association Studies (STREGA)--an extension of the STROBE statement. Genetic Epidemiology. 33: 581-98. PMID 19278015 DOI: 10.1002/Gepi.20410 |
0.318 |
|
| 2009 |
Vink JM, Smit AB, de Geus EJ, Sullivan P, Willemsen G, Hottenga JJ, Smit JH, Hoogendijk WJ, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Magnusson PK, Spector TD, Kyvik KO, ... ... van Duijn C, et al. Genome-wide association study of smoking initiation and current smoking. American Journal of Human Genetics. 84: 367-79. PMID 19268276 DOI: 10.1016/J.Ajhg.2009.02.001 |
0.457 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. Journal of Clinical Epidemiology. 62: 597-608.e4. PMID 19217256 DOI: 10.1016/J.Jclinepi.2008.12.004 |
0.315 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. Plos Medicine. 6: e22. PMID 19192942 DOI: 10.1371/Journal.Pmed.1000022 |
0.318 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement. Annals of Internal Medicine. 150: 206-15. PMID 19189911 DOI: 10.7326/0003-4819-150-3-200902030-00011 |
0.318 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement. European Journal of Epidemiology. 24: 37-55. PMID 19189221 DOI: 10.1007/S10654-008-9302-Y |
0.318 |
|
| 2009 |
Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, ... ... van Duijn C, et al. Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Human Genetics. 125: 131-51. PMID 19184668 DOI: 10.1007/S00439-008-0592-7 |
0.318 |
|
| 2009 |
Despriet DDG, van Duijn CM, Oostra BA, Uitterlinden AG, Hofman A, Wright AF, ten Brink JB, Bakker A, de Jong PTVM, Vingerling JR, Bergen AAB, Klaver CCW. Complement Component C3 and Risk of Age-Related Macular Degeneration Ophthalmology. 116: 474-480.e2. PMID 19168221 DOI: 10.1016/J.Ophtha.2008.09.055 |
0.485 |
|
| 2009 |
Zillikens MC, van Meurs JB, Sijbrands EJ, Rivadeneira F, Dehghan A, van Leeuwen JP, Hofman A, van Duijn CM, Witteman JC, Uitterlinden AG, Pols HA. SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin. Free Radical Biology & Medicine. 46: 836-41. PMID 19167483 DOI: 10.1016/J.Freeradbiomed.2008.12.022 |
0.315 |
|
| 2009 |
Amin N, Aulchenko YS, Dekker MC, Ferdinand RF, van Spreeken A, Temmink AH, Verhulst FC, Oostra BA, van Duijn CM. Suggestive linkage of ADHD to chromosome 18q22 in a young genetically isolated Dutch population. European Journal of Human Genetics : Ejhg. 17: 958-66. PMID 19156173 DOI: 10.1038/Ejhg.2008.260 |
0.487 |
|
| 2009 |
Choy WC, López-León S, Aulchenko YS, Mackenbach JP, Oostra BA, van Duijn CM, Janssens AC. Role of shared genetic and environmental factors in symptoms of depression and body composition. Psychiatric Genetics. 19: 32-8. PMID 19125106 DOI: 10.1097/YPG.0b013e328320804e |
0.364 |
|
| 2009 |
Ikram MA, Liu F, Oostra BA, Hofman A, van Duijn CM, Breteler MM. The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis. Biological Psychiatry. 65: 995-9. PMID 19118819 DOI: 10.1016/J.Biopsych.2008.11.014 |
0.668 |
|
| 2009 |
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, ... ... Van Duijn CM, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics. 41: 25-34. PMID 19079261 DOI: 10.1038/Ng.287 |
0.402 |
|
| 2009 |
Sie MP, Mattace-Raso FU, Uitterlinden AG, Arp PP, Hofman A, Pols HA, Hoeks AP, Reneman RS, Asmar R, van Duijn CM, Witteman JC. The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study. Vascular Health and Risk Management. 4: 863-9. PMID 19066003 DOI: 10.2147/Vhrm.S1693 |
0.338 |
|
| 2009 |
Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, ... ... van Duijn CM, et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nature Genetics. 41: 47-55. PMID 19060911 DOI: 10.1038/Ng.269 |
0.556 |
|
| 2009 |
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, ... ... Van Duijn C, et al. Variants in MTNR1B influence fasting glucose levels. Nature Genetics. 41: 77-81. PMID 19060907 DOI: 10.1038/Ng.290 |
0.428 |
|
| 2009 |
Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Dunlop MG, Floyd J, Hastie N, Hofman A, ... ... van Duijn CM, et al. Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Human Molecular Genetics. 18: 373-80. PMID 18952825 DOI: 10.1093/Hmg/Ddn350 |
0.612 |
|
| 2008 |
Jaddoe VW, van Duijn CM, van der Heijden AJ, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study: design and cohort update until the age of 4 years. European Journal of Epidemiology. 23: 801-11. PMID 19101808 DOI: 10.1007/S10654-008-9309-4 |
0.423 |
|
| 2008 |
Coppus AM, Evenhuis HM, Verberne GJ, Visser FE, Oostra BA, Eikelenboom P, van Gool WA, Janssens AC, van Duijn CM. Survival in elderly persons with Down syndrome. Journal of the American Geriatrics Society. 56: 2311-6. PMID 19093931 DOI: 10.1111/j.1532-5415.2008.01999.x |
0.397 |
|
| 2008 |
Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von Und Zu Fraunberg M, van Duijn CM, van den Berg LH, Mane S, Mason CE, Choi M, Gaál E, Bayri Y, Kolb L, Arlier Z, Ravuri S, et al. Susceptibility loci for intracranial aneurysm in European and Japanese populations. Nature Genetics. 40: 1472-7. PMID 18997786 DOI: 10.1038/Ng.240 |
0.495 |
|
| 2008 |
Aulchenko YS, Hoppenbrouwers IA, Ramagopalan SV, Broer L, Jafari N, Hillert J, Link J, Lundström W, Greiner E, Dessa Sadovnick A, Goossens D, Van Broeckhoven C, Del-Favero J, Ebers GC, Oostra BA, ... van Duijn CM, et al. Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. Nature Genetics. 40: 1402-3. PMID 18997785 DOI: 10.1038/Ng.251 |
0.462 |
|
| 2008 |
Dehghan A, van Hoek M, Sijbrands EJ, Oostra BA, Hofman A, van Duijn CM, Witteman JC. Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study. Bmc Medicine. 6: 30. PMID 18925945 DOI: 10.1186/1741-7015-6-30 |
0.57 |
|
| 2008 |
Dehghan A, Köttgen A, Yang Q, Hwang SJ, Kao WL, Rivadeneira F, Boerwinkle E, Levy D, Hofman A, Astor BC, Benjamin EJ, van Duijn CM, Witteman JC, Coresh J, Fox CS. Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study The Lancet. 372: 1953-1961. PMID 18834626 DOI: 10.1016/S0140-6736(08)61343-4 |
0.459 |
|
| 2008 |
Boekhoorn SS, Isaacs A, Uitterlinden AG, van Duijn CM, Hofman A, de Jong PT, Vingerling JR. Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study. Ophthalmology. 115: 1899-903. PMID 18708255 DOI: 10.1016/J.Ophtha.2008.06.026 |
0.301 |
|
| 2008 |
van Hoek M, Dehghan A, Witteman JC, van Duijn CM, Uitterlinden AG, Oostra BA, Hofman A, Sijbrands EJ, Janssens AC. Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes. 57: 3122-8. PMID 18694974 DOI: 10.2337/Db08-0425 |
0.557 |
|
| 2008 |
López-León S, Janssens AC, Tiemeier H, Hofman A, Aulchenko YS, Snijders PJ, Claes S, Oostra BA, van Duijn CM. Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study. Psychiatric Genetics. 18: 162-6. PMID 18628677 DOI: 10.1097/Ypg.0B013E3282Fb7Fd6 |
0.57 |
|
| 2008 |
Berends AL, Steegers EA, Isaacs A, Aulchenko YS, Liu F, de Groot CJ, Oostra BA, van Duijn CM. Familial aggregation of preeclampsia and intrauterine growth restriction in a genetically isolated population in The Netherlands. European Journal of Human Genetics : Ejhg. 16: 1437-42. PMID 18612323 DOI: 10.1038/ejhg.2008.118 |
0.395 |
|
| 2008 |
van Houten VA, Mook-Kanamori DO, van Osch-Gevers L, Steegers EA, Hofman A, Moll HA, van Duijn CM, Helbing WA, Hokken-Koelega AC, Jaddoe VW. A variant of the IGF-I gene is associated with blood pressure but not with left heart dimensions at the age of 2 years: the Generation R Study. European Journal of Endocrinology. 159: 209-16. PMID 18544576 DOI: 10.1530/Eje-07-0907 |
0.356 |
|
| 2008 |
Duijts L, Bakker-Jonges LE, Mook-Kanamori DO, Labout JA, Hofman A, van Duijn CM, van Dongen JJ, Hooijkaas H, Moll HA, Jaddoe VW. Variation in the IGF-1 gene is associated with lymphocyte subset counts in neonates: the Generation R Study. Clinical Endocrinology. 70: 53-9. PMID 18466350 DOI: 10.1111/J.1365-2265.2008.03294.X |
0.319 |
|
| 2008 |
Arias-Vásquez A, Aulchenko YS, Isaacs A, van Oosterhout A, Sleegers K, Hofman A, van Broeckhoven C, Oostra BA, Breteler M, van Duijn CM. Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study. Journal of Neurology. 255: 655-62. PMID 18350355 DOI: 10.1007/S00415-008-0770-5 |
0.749 |
|
| 2008 |
Hoppenbrouwers IA, Liu F, Aulchenko YS, Ebers GC, Oostra BA, van Duijn CM, Hintzen RQ. Maternal transmission of multiple sclerosis in a dutch population. Archives of Neurology. 65: 345-8. PMID 18332246 DOI: 10.1001/archneurol.2007.63 |
0.333 |
|
| 2008 |
Janssens ACJW, Gwinn M, Bradley LA, Oostra BA, van Duijn CM, Khoury MJ. A Critical Appraisal of the Scientific Basis of Commercial Genomic Profiles Used to Assess Health Risks and Personalize Health Interventions American Journal of Human Genetics. 82: 593-599. PMID 18319070 DOI: 10.1016/j.ajhg.2007.12.020 |
0.539 |
|
| 2008 |
Berends AL, de Groot CJ, Sijbrands EJ, Sie MP, Benneheij SH, Pal R, Heydanus R, Oostra BA, van Duijn CM, Steegers EA. Shared constitutional risks for maternal vascular-related pregnancy complications and future cardiovascular disease. Hypertension (Dallas, Tex. : 1979). 51: 1034-41. PMID 18259037 DOI: 10.1161/HYPERTENSIONAHA.107.101873 |
0.393 |
|
| 2008 |
Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, ... ... van Duijn CM, et al. Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. American Journal of Human Genetics. 82: 411-23. PMID 18252221 DOI: 10.1016/J.Ajhg.2007.10.003 |
0.589 |
|
| 2007 |
Sánchez-Juan P, Bishop MT, Green A, Giannattasio C, Arias-Vasquez A, Poleggi A, Knight RS, van Duijn CM. No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease. Bmc Medical Genetics. 8: 77. PMID 18072964 DOI: 10.1186/1471-2350-8-77 |
0.317 |
|
| 2007 |
Hofman A, Breteler MM, van Duijn CM, Krestin GP, Pols HA, Stricker BH, Tiemeier H, Uitterlinden AG, Vingerling JR, Witteman JC. The Rotterdam Study: objectives and design update. European Journal of Epidemiology. 22: 819-29. PMID 17955331 DOI: 10.1007/s10654-007-9199-x |
0.566 |
|
| 2007 |
Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A, Vaessen N, Snijders PJ, Zubakov D, Mackay I, Olavesen M, Sidhu B, Smith VE, Carey A, Berezikov E, Uitterlinden AG, ... ... van Duijn CM, et al. LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition. Diabetes. 56: 3020-6. PMID 17804763 DOI: 10.2337/Db07-0338 |
0.557 |
|
| 2007 |
van Koolwijk LM, Despriet DD, van Duijn CM, Pardo Cortes LM, Vingerling JR, Aulchenko YS, Oostra BA, Klaver CC, Lemij HG. Genetic contributions to glaucoma: heritability of intraocular pressure, retinal nerve fiber layer thickness, and optic disc morphology. Investigative Ophthalmology & Visual Science. 48: 3669-76. PMID 17652737 DOI: 10.1167/IOVS.06-1519 |
0.4 |
|
| 2007 |
Liu F, Arias-Vásquez A, Sleegers K, Aulchenko YS, Kayser M, Sanchez-Juan P, Feng BJ, Bertoli-Avella AM, van Swieten J, Axenovich TI, Heutink P, van Broeckhoven C, Oostra BA, van Duijn CM. A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population. American Journal of Human Genetics. 81: 17-31. PMID 17564960 DOI: 10.1086/518720 |
0.704 |
|
| 2007 |
Arias-Vásquez A, Isaacs A, Aulchenko YS, Hofman A, Oostra BA, Breteler M, van Duijn CM. The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease. Neurogenetics. 8: 189-93. PMID 17503098 DOI: 10.1007/S10048-007-0089-X |
0.653 |
|
| 2007 |
Boekhoorn SS, Vingerling JR, Uitterlinden AG, Van Meurs JB, van Duijn CM, Pols HA, Hofman A, de Jong PT. Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder. Investigative Ophthalmology & Visual Science. 48: 1012-7. PMID 17325140 DOI: 10.1167/Iovs.06-0577 |
0.35 |
|
| 2007 |
Isaacs A, Sayed-Tabatabaei FA, Aulchenko YS, Zillikens MC, Sijbrands EJ, Schut AF, Rutten WP, Pols HA, Witteman JC, Oostra BA, van Duijn CM. Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: the Erasmus Rucphen Family Study. European Journal of Epidemiology. 22: 99-105. PMID 17318336 DOI: 10.1007/s10654-006-9103-0 |
0.433 |
|
| 2007 |
Schelleman H, Klungel OH, Witteman JC, Breteler MM, Yazdanpanah M, Danser AH, Hofman A, van Duijn CM, de Boer A, Stricker BH. Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or beta-blockers. European Journal of Human Genetics : Ejhg. 15: 478-84. PMID 17299437 DOI: 10.1038/Sj.Ejhg.5201789 |
0.502 |
|
| 2007 |
van Rijn MJ, Schut AF, Aulchenko YS, Deinum J, Sayed-Tabatabaei FA, Yazdanpanah M, Isaacs A, Axenovich TI, Zorkoltseva IV, Zillikens MC, Pols HA, Witteman JC, Oostra BA, van Duijn CM. Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes. Journal of Hypertension. 25: 565-70. PMID 17278972 DOI: 10.1097/HJH.0b013e32801449fb |
0.378 |
|
| 2007 |
van Dijk EJ, Prins ND, Hofman A, van Duijn CM, Koudstaal PJ, Breteler MM. Plasma beta amyloid and impaired CO2-induced cerebral vasomotor reactivity. Neurobiology of Aging. 28: 707-12. PMID 16698128 DOI: 10.1016/J.Neurobiolaging.2006.03.011 |
0.466 |
|
| 2006 |
López-León S, Janssens AC, Hofman A, Claes S, Breteler MM, Tiemeier H, van Duijn CM. No association between the angiotensin-converting enzyme gene and major depression: a case-control study and meta-analysis. Psychiatric Genetics. 16: 225-6. PMID 17106418 DOI: 10.1097/01.Ypg.0000242191.51397.3D |
0.58 |
|
| 2006 |
van Rijn MJ, Bos MJ, Yazdanpanah M, Isaacs A, Arias-Vásquez A, Koudstaal PJ, Hofman A, Witteman JC, van Duijn CM, Breteler MM. Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk. Stroke; a Journal of Cerebral Circulation. 37: 2930-4. PMID 17082469 DOI: 10.1161/01.Str.0000248760.67039.2B |
0.535 |
|
| 2006 |
van der Vleuten GM, Isaacs A, Hijmans A, van Duijn CM, Stalenhoef AF, de Graaf J. The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia. Journal of Lipid Research. 48: 193-200. PMID 17065663 DOI: 10.1194/jlr.M600184-JLR200 |
0.302 |
|
| 2006 |
Sie MP, Uitterlinden AG, Bos MJ, Arp PP, Breteler MM, Koudstaal PJ, Pols HA, Hofman A, van Duijn CM, Witteman JC. TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke: the Rotterdam Study. Stroke; a Journal of Cerebral Circulation. 37: 2667-71. PMID 17023672 DOI: 10.1161/01.Str.0000244779.30070.1A |
0.525 |
|
| 2006 |
Rivadeneira F, Van Meurs JBJ, Kant J, Zillikens MC, Stolk L, Beck TJ, Arp P, Schuit SCE, Hofman A, Houwing-Duistermaat JJ, Van Duijn CM, Van Leeuwen JPTM, Pols HAP, Uitterlinden AG. Estrogen receptor β (ESR2) polymorphisms in interaction with estrogen receptor α (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women Journal of Bone and Mineral Research. 21: 1443-1456. PMID 16939403 DOI: 10.1359/Jbmr.060605 |
0.34 |
|
| 2006 |
Sleegers K, Brouwers N, Gijselinck I, Theuns J, Goossens D, Wauters J, Del-Favero J, Cruts M, van Duijn CM, Van Broeckhoven C. APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy. Brain : a Journal of Neurology. 129: 2977-83. PMID 16921174 DOI: 10.1093/Brain/Awl203 |
0.524 |
|
| 2006 |
Hofman A, de Jong PT, van Duijn CM, Breteler MM. Epidemiology of neurological diseases in elderly people: what did we learn from the Rotterdam Study? The Lancet. Neurology. 5: 545-50. PMID 16713926 DOI: 10.1016/S1474-4422(06)70473-2 |
0.476 |
|
| 2006 |
Theuns J, Brouwers N, Engelborghs S, Sleegers K, Bogaerts V, Corsmit E, De Pooter T, van Duijn CM, De Deyn PP, Van Broeckhoven C. Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease. American Journal of Human Genetics. 78: 936-46. PMID 16685645 DOI: 10.1086/504044 |
0.498 |
|
| 2006 |
Service S, DeYoung J, Karayiorgou M, Roos JL, Pretorious H, Bedoya G, Ospina J, Ruiz-Linares A, Macedo A, Palha JA, Heutink P, Aulchenko Y, Oostra B, van Duijn C, Jarvelin MR, et al. Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nature Genetics. 38: 556-60. PMID 16582909 DOI: 10.1038/Ng1770 |
0.485 |
|
| 2006 |
Ikram MK, Janssen JA, Roos AM, Rietveld I, Witteman JC, Breteler MM, Hofman A, van Duijn CM, de Jong PT. Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study. Diabetes. 55: 506-10. PMID 16443787 DOI: 10.2337/Diabetes.55.02.06.Db05-0546 |
0.482 |
|
| 2006 |
Brouwers N, Sleegers K, Engelborghs S, Bogaerts V, van Duijn CM, De Deyn PP, Van Broeckhoven C, Dermaut B. The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years. Neuroscience Letters. 392: 72-4. PMID 16214290 DOI: 10.1016/J.Neulet.2005.08.064 |
0.563 |
|
| 2006 |
van West D, Van Den Eede F, Del-Favero J, Souery D, Norrback KF, Van Duijn C, Sluijs S, Adolfsson R, Mendlewicz J, Deboutte D, Van Broeckhoven C, Claes S. Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 620-7. PMID 16192984 DOI: 10.1038/Sj.Npp.1300898 |
0.332 |
|
| 2005 |
Bertoli-Avella AM, Dekker MC, Aulchenko YS, Houwing-Duistermaat JJ, Simons E, Testers L, Pardo LM, Rademaker TA, Snijders PJ, van Swieten JC, Bonifati V, Heutink P, van Duijn CM, Oostra BA. Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands. Human Genetics. 119: 51-60. PMID 16369765 DOI: 10.1007/s00439-005-0108-7 |
0.605 |
|
| 2005 |
Rademakers R, Cruts M, Sleegers K, Dermaut B, Theuns J, Aulchenko Y, Weckx S, De Pooter T, Van den Broeck M, Corsmit E, De Rijk P, Del-Favero J, van Swieten J, van Duijn CM, Van Broeckhoven C. Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample. American Journal of Human Genetics. 77: 643-52. PMID 16175510 DOI: 10.1086/491749 |
0.655 |
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| 2005 |
Croes EA, El Galta R, Houwing-Duistermaat JJ, Ferdinand RF, López León S, Rademaker TA, Dekker MC, Oostra BA, Verhulst F, Van Duijn CM. Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population. European Journal of Epidemiology. 20: 789-94. PMID 16170663 DOI: 10.1007/S10654-005-0366-7 |
0.4 |
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| 2005 |
Lehmann DJ, Cortina-Borja M, Warden DR, Smith AD, Sleegers K, Prince JA, van Duijn CM, Kehoe PG. Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease. American Journal of Epidemiology. 162: 305-17. PMID 16033878 DOI: 10.1093/aje/kwi202 |
0.568 |
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| 2005 |
Sleegers K, den Heijer T, van Dijk EJ, Hofman A, Bertoli-Avella AM, Koudstaal PJ, Breteler MM, van Duijn CM. ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala. Neurobiology of Aging. 26: 1153-9. PMID 15917098 DOI: 10.1016/J.Neurobiolaging.2004.09.011 |
0.671 |
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| 2005 |
Bleumink GS, Schut AF, Sturkenboom MC, van Duijn CM, Deckers JW, Hofman A, Kingma JH, Witteman JC, Stricker BH. Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism. Pharmacogenetics and Genomics. 15: 75-81. PMID 15861031 DOI: 10.1097/01213011-200502000-00003 |
0.304 |
|
| 2005 |
Pardo LM, MacKay I, Oostra B, van Duijn CM, Aulchenko YS. The effect of genetic drift in a young genetically isolated population. Annals of Human Genetics. 69: 288-95. PMID 15845033 DOI: 10.1046/J.1529-8817.2005.00162.X |
0.432 |
|
| 2005 |
Bertoli-Avella AM, Giroud-Benitez JL, Akyol A, Barbosa E, Schaap O, van der Linde HC, Martignoni E, Lopiano L, Lamberti P, Fincati E, Antonini A, Stocchi F, Montagna P, Squitieri F, Marini P, ... ... van Duijn CM, et al. Novel parkin mutations detected in patients with early-onset Parkinson's disease Movement Disorders. 20: 424-431. PMID 15584030 DOI: 10.1002/mds.20343 |
0.388 |
|
| 2005 |
Aulchenko YS, Heutink P, Mackay I, Bertoli-Avella AM, Pullen J, Vaessen N, Rademaker TA, Sandkuijl LA, Cardon L, Oostra B, van Duijn CM. Linkage disequilibrium in young genetically isolated Dutch population. European Journal of Human Genetics : Ejhg. 12: 527-34. PMID 15054401 DOI: 10.1038/sj.ejhg.5201188 |
0.458 |
|
| 2004 |
Arias Vásquez A, Sleegers K, Dekker MC, van Gool WA, van Swieten JC, Aulchenko YS, Oostra BA, van Duijn CM. A deletion in DJ-1 and the risk of dementia--a population-based survey. Neuroscience Letters. 372: 196-9. PMID 15542239 DOI: 10.1016/j.neulet.2004.09.040 |
0.698 |
|
| 2004 |
den Heijer T, Vermeer SE, van Dijk EJ, Prins ND, Koudstaal PJ, van Duijn CM, Hofman A, Breteler MM. Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia. The American Journal of Clinical Nutrition. 80: 992-7. PMID 15447910 DOI: 10.1093/Ajcn/80.4.992 |
0.458 |
|
| 2004 |
Mattace-Raso FU, van der Cammen TJ, Sayed-Tabatabaei FA, van Popele NM, Asmar R, Schalekamp MA, Hofman A, van Duijn CM, Witteman JC. Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study. Atherosclerosis. 174: 121-6. PMID 15135260 DOI: 10.1016/J.Atherosclerosis.2004.01.012 |
0.359 |
|
| 2004 |
Schut AF, Sayed-Tabatabaei FA, Witteman JC, Avella AM, Vergeer JM, Pols HA, Hofman A, Deinum J, van Duijn CM. Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure. Journal of Hypertension. 22: 313-9. PMID 15076189 DOI: 10.1097/00004872-200402000-00015 |
0.351 |
|
| 2004 |
de Leeuw FE, Richard F, de Groot JC, van Duijn CM, Hofman A, Van Gijn J, Breteler MM. Interaction between hypertension, apoE, and cerebral white matter lesions. Stroke; a Journal of Cerebral Circulation. 35: 1057-60. PMID 15060316 DOI: 10.1161/01.Str.0000125859.71051.83 |
0.532 |
|
| 2004 |
van Dijk EJ, Prins ND, Vermeer SE, Hofman A, van Duijn CM, Koudstaal PJ, Breteler MM. Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions. Annals of Neurology. 55: 570-5. PMID 15048897 DOI: 10.1002/Ana.20050 |
0.489 |
|
| 2004 |
Croes EA, Alizadeh BZ, Bertoli-Avella AM, Rademaker T, Vergeer-Drop J, Dermaut B, Houwing-Duistermaat JJ, Wientjens DP, Hofman A, Van Broeckhoven C, van Duijn CM. Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease. European Journal of Human Genetics : Ejhg. 12: 389-94. PMID 14970845 DOI: 10.1038/Sj.Ejhg.5201161 |
0.415 |
|
| 2004 |
Dekker M, Bonifati V, van Swieten J, Leenders N, Galjaard RJ, Snijders P, Horstink M, Heutink P, Oostra B, van Duijn C. Clinical features and neuroimaging of PARK7-linked parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 751-7. PMID 12815653 DOI: 10.1002/mds.10422 |
0.554 |
|
| 2003 |
Fang Y, van Meurs JB, Bergink AP, Hofman A, van Duijn CM, van Leeuwen JP, Pols HA, Uitterlinden AG. Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1632-41. PMID 12968672 DOI: 10.1359/Jbmr.2003.18.9.1632 |
0.364 |
|
| 2003 |
Dekker MC, Giesbergen PC, Njajou OT, van Swieten JC, Hofman A, Breteler MM, van Duijn CM. Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism. Neuroscience Letters. 348: 117-9. PMID 12902032 DOI: 10.1016/S0304-3940(03)00713-4 |
0.582 |
|
| 2003 |
Croes EA, Dermaut B, Houwing-Duistermaat JJ, Van den Broeck M, Cruts M, Breteler MM, Hofman A, van Broeckhoven C, van Duijn CM. Early cognitive decline is associated with prion protein codon 129 polymorphism. Annals of Neurology. 54: 275-6. PMID 12891686 DOI: 10.1002/Ana.10658 |
0.501 |
|
| 2003 |
Bergink AP, van Meurs JB, Loughlin J, Arp PP, Fang Y, Hofman A, van Leeuwen JP, van Duijn CM, Uitterlinden AG, Pols HA. Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women. Arthritis and Rheumatism. 48: 1913-22. PMID 12847685 DOI: 10.1002/Art.11046 |
0.375 |
|
| 2003 |
van Meurs JB, Schuit SC, Weel AE, van der Klift M, Bergink AP, Arp PP, Colin EM, Fang Y, Hofman A, van Duijn CM, van Leeuwen JP, Pols HA, Uitterlinden AG. Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk. Human Molecular Genetics. 12: 1745-54. PMID 12837697 DOI: 10.1093/Hmg/Ddg176 |
0.378 |
|
| 2003 |
Dermaut B, Croes EA, Rademakers R, Van den Broeck M, Cruts M, Hofman A, van Duijn CM, Van Broeckhoven C. PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease. Annals of Neurology. 53: 409-12. PMID 12601712 DOI: 10.1002/Ana.10507 |
0.364 |
|
| 2003 |
Rietveld I, Janssen JA, Hofman A, Pols HA, van Duijn CM, Lamberts SW. A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels. European Journal of Endocrinology. 148: 171-5. PMID 12590635 DOI: 10.1530/eje.0.1480171 |
0.36 |
|
| 2003 |
Njajou OT, de Jong G, Berghuis B, Vaessen N, Snijders PJ, Goossens JP, Wilson JH, Breuning MH, Oostra BA, Heutink P, Sandkuijl LA, van Duijn CM. Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics. Blood Cells, Molecules & Diseases. 29: 439-43. PMID 12547233 DOI: 10.1006/BCMD.2002.0581 |
0.392 |
|
| 2002 |
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, ... van Duijn CM, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science (New York, N.Y.). 299: 256-9. PMID 12446870 DOI: 10.1126/SCIENCE.1077209 |
0.572 |
|
| 2002 |
Maitland-van der Zee AH, Stricker BH, Klungel OH, Kastelein JJ, Hofman A, Witteman JC, Breteler MM, Leufkens HG, van Duijn CM, de Boer A. The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype. Pharmacogenetics. 12: 647-53. PMID 12439225 DOI: 10.1097/00008571-200211000-00009 |
0.489 |
|
| 2002 |
Njajou OT, Hollander M, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM, van Duijn CM. Mutations in the hemochromatosis gene (HFE) and stroke. Stroke; a Journal of Cerebral Circulation. 33: 2363-6. PMID 12364722 DOI: 10.1161/01.Str.0000029779.37078.C7 |
0.476 |
|
| 2002 |
Dermaut B, Theuns J, Sleegers K, Hasegawa H, Van den Broeck M, Vennekens K, Corsmit E, St George-Hyslop P, Cruts M, van Duijn CM, Van Broeckhoven C. The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample. American Journal of Human Genetics. 70: 1568-74. PMID 11992262 DOI: 10.1086/340732 |
0.554 |
|
| 2002 |
Njajou OT, Vaessen N, Oostra B, Heutink P, Van Duijn CM. The hemochromatosis N144H mutation of SLC11A3 gene in patients with type 2 diabetes. Molecular Genetics and Metabolism. 75: 290-1. PMID 11914044 DOI: 10.1006/MGME.2002.3299 |
0.35 |
|
| 2002 |
Vaessen N, Heutink P, Houwing-Duistermaat JJ, Snijders PJ, Rademaker T, Testers L, Batstra MR, Sandkuijl LA, van Duijn CM, Oostra BA. A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands. Diabetes. 51: 856-9. PMID 11872691 DOI: 10.2337/DIABETES.51.3.856 |
0.486 |
|
| 2002 |
Bonifati V, Breedveld GJ, Squitieri F, Vanacore N, Brustenghi P, Harhangi BS, Montagna P, Cannella M, Fabbrini G, Rizzu P, van Duijn CM, Oostra BA, Meco G, Heutink P. Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset. Annals of Neurology. 51: 253-6. PMID 11835383 DOI: 10.1002/ana.10106 |
0.418 |
|
| 2002 |
Ruitenberg A, van Swieten JC, Witteman JC, Mehta KM, van Duijn CM, Hofman A, Breteler MM. Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet. 359: 281-6. PMID 11830193 DOI: 10.1016/S0140-6736(02)07493-7 |
0.607 |
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