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Nelli Mnatsakanyan - Publications

Affiliations: 
Yale University School of Medicine, New Haven, CT 
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bernardi P, Gerle C, Halestrap AP, Jonas EA, Karch J, Mnatsakanyan N, Pavlov E, Sheu SS, Soukas AA. Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions. Cell Death and Differentiation. PMID 37460667 DOI: 10.1038/s41418-023-01187-0  0.34
2022 Mnatsakanyan N, Park HA, Wu J, He X, Llaguno MC, Latta M, Miranda P, Murtishi B, Graham M, Weber J, Levy RJ, Pavlov EV, Jonas EA. Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F subcomplex. Cell Death and Differentiation. PMID 35322203 DOI: 10.1038/s41418-022-00972-7  0.62
2021 Li Y, Valdez NA, Mnatsakanyan N, Weber J. The nucleotide binding affinities of two critical conformations of Escherichia coli ATP synthase. Archives of Biochemistry and Biophysics. 108899. PMID 33991499 DOI: 10.1016/j.abb.2021.108899  0.675
2021 Dotson RJ, Mnatsakanyan N, Jonas EA, Pias SC. Wetting Transitions in the ATP Synthase C-Subunit Ring, a Large-Conductance Ion Channel Biophysical Journal. 120: 194a. DOI: 10.1016/J.BPJ.2020.11.1335  0.328
2020 Licznerski P, Park HA, Rolyan H, Chen R, Mnatsakanyan N, Miranda P, Graham M, Wu J, Cruz-Reyes N, Mehta N, Sohail S, Salcedo J, Song E, Effman C, Effman S, et al. ATP Synthase c-Subunit Leak Causes Aberrant Cellular Metabolism in Fragile X Syndrome. Cell. PMID 32795412 DOI: 10.1016/J.Cell.2020.07.008  0.391
2020 Mnatsakanyan N, Jonas EA. The new role of FF ATP synthase in mitochondria-mediated neurodegeneration and neuroprotection. Experimental Neurology. 332: 113400. PMID 32653453 DOI: 10.1016/j.expneurol.2020.113400  0.432
2020 Mnatsakanyan N, Jonas EA. ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: Regulator of metabolism in development and degeneration. Journal of Molecular and Cellular Cardiology. 144: 109-118. PMID 32461058 DOI: 10.1016/j.yjmcc.2020.05.013  0.355
2020 Dunn T, Brown S, Mnatsakanyan N, Jonas E, Yonghyun K, Park H. Cellular Mechanisms of Metabolic Remodeling During Fluid Sheer Stress-Induced Metastasis Current Developments in Nutrition. 4: 322-322. DOI: 10.1093/cdn/nzaa044_021  0.353
2020 Jonas E, Mnatsakanyan N, Alavian KN, Chen R. Mitochondrial (ATP Synthase) Permeability Transition Pore Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.269  0.361
2020 Mnatsakanyan N, Llaguno MC, Yang Y, Yan Y, Weber J, Sigworth FJ, Jonas EA. Structural and Pharmacological Characterization of the Mitochondrial Permeability Transition Pore: A Megachannel Formed by F1FO ATP Synthase Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.198  0.362
2019 Mnatsakanyan N, Llaguno MC, Yang Y, Yan Y, Weber J, Sigworth FJ, Jonas EA. A mitochondrial megachannel resides in monomeric FF ATP synthase. Nature Communications. 10: 5823. PMID 31862883 DOI: 10.1038/S41467-019-13766-2  0.632
2019 Chen R, Park HA, Mnatsakanyan N, Niu Y, Licznerski P, Wu J, Miranda P, Graham M, Tang J, Boon AJW, Cossu G, Mandemakers W, Bonifati V, Smith PJS, Alavian KN, et al. Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth. Cell Death & Disease. 10: 469. PMID 31197129 DOI: 10.1038/S41419-019-1679-X  0.475
2019 Neginskaya MA, Solesio ME, Berezhnaya EV, Amodeo GF, Mnatsakanyan N, Jonas EA, Pavlov EV. ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore. Cell Reports. 26: 11-17.e2. PMID 30605668 DOI: 10.1016/j.celrep.2018.12.033  0.371
2019 Mnatsakanyan N, Li Y, Weber J. Identification of two segments of the γ subunit of ATP synthase responsible for the different affinities of the catalytic nucleotide-binding sites. The Journal of Biological Chemistry. 294: 1152-1160. PMID 30510135 DOI: 10.1074/jbc.RA118.002504  0.677
2019 Mnatsakanyan N, Park H, Jing W, Llaguno MC, Murtishi B, Latta M, Davis E, Miranda P, Yang Y, Sigworth F, Jonas EA. Mitochondrial Megachannel Resides in Monomeric ATP Synthase Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.863  0.396
2018 Mnatsakanyan N, Park H, Wu J, Miranda P, Jonas EA. The role of ATP synthase megachannel in mitochondrial permeability transition Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1859: e112. DOI: 10.1016/J.Bbabio.2018.09.330  0.36
2017 Mnatsakanyan N, Park H, Wu J, Miranda P, Jonas EA. New Insights into the Molecular Structure and Regulation of the Mitochondrial Permeability Transition Pore Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2349  0.44
2016 Mnatsakanyan N, Beutner G, Porter GA, Alavian KN, Jonas EA. Physiological roles of the mitochondrial permeability transition pore. Journal of Bioenergetics and Biomembranes. PMID 26868013 DOI: 10.1007/s10863-016-9652-1  0.401
2016 Elustondo PA, Mnatsakanyan N, Eleonora Z, Jonas EA, Pavlov E. Mitochondrial Permeability Transition Pore (mPTP) Formation Requires the Participation of c-Subunit of ATP-Synthase, Polyhydroxybutyrate (PHB) and Inorganic Polyphosphate (polyP) Biophysical Journal. 110: 310a. DOI: 10.1016/J.BPJ.2015.11.1666  0.402
2016 Mnatsakanyan N, Park H, Wu J, Miranda P, Jonas EA. A Novel Ion Channel in ATP Synthase C-Subunit Ring: Gatekeeper of Life and Death Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1664  0.403
2015 Jonas EA, Porter GA, Beutner G, Mnatsakanyan N, Alavian KN. Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F1FO ATP synthase. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. PMID 25956324 DOI: 10.1016/j.phrs.2015.04.013  0.394
2011 Mnatsakanyan N, Kemboi SK, Salas J, Weber J. The beta subunit loop that couples catalysis and rotation in ATP synthase has a critical length. The Journal of Biological Chemistry. 286: 29788-96. PMID 21705326 DOI: 10.1074/jbc.M111.254730  0.688
2009 Mnatsakanyan N, Hook JA, Quisenberry L, Weber J. ATP synthase with its gamma subunit reduced to the N-terminal helix can still catalyze ATP synthesis. The Journal of Biological Chemistry. 284: 26519-25. PMID 19636076 DOI: 10.1074/jbc.M109.030528  0.691
2009 Mnatsakanyan N, Krishnakumar AM, Suzuki T, Weber J. The role of the betaDELSEED-loop of ATP synthase. The Journal of Biological Chemistry. 284: 11336-45. PMID 19246448 DOI: 10.1074/jbc.M900374200  0.694
2008 Madireddy SD, Mnatsakanyan N, Mao HZ, Krishnakumar AM, Brown RH, Hook JA, Weber J. S1.11 Mutational analysis of the function of the βDELSEED-Loop of ATP synthase Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1777: S11. DOI: 10.1016/J.BBABIO.2008.05.049  0.595
2003 Mnatsakanyan N, Poladian A, Bagramyan K, Trchounian A. The number of accessible SH-groups in Escherichia coli membrane vesicles is increased by ATP or by formate. Biochemical and Biophysical Research Communications. 308: 655-9. PMID 12914800 DOI: 10.1016/s0006-291x(03)01460-8  0.311
2000 BAGRAMYAN K, MNATSAKANYAN N, POLADIAN A, VASSILIAN A, TRCHOUNIAN A. Escherichia coli formate hydrogenlyase pathways: a requirement of the F0F1 ATP synthase for the activity of hydrogenase 4 Biochemical Society Transactions. 28: A187-A187. DOI: 10.1042/BST028A187  0.359
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