Year |
Citation |
Score |
2022 |
Napoleon JV, Sagar S, Kubica SP, Boghean L, Kour S, King HM, Sonawane YA, Crawford AJ, Gautam N, Kizhake S, Bialk PA, Kmiec E, Mallareddy JR, Patil PP, Rana S, et al. Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 119: e2115071119. PMID 35476515 DOI: 10.1073/pnas.2115071119 |
0.776 |
|
2022 |
Rana S, Kour S, Kizhake S, King HM, Mallareddy JR, Case AJ, Huxford T, Natarajan A. Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 65: 128713. PMID 35367592 DOI: 10.1016/j.bmcl.2022.128713 |
0.808 |
|
2021 |
King HM, Rana S, Kubica SP, Mallareddy JR, Kizhake S, Ezell EL, Zahid M, Naldrett MJ, Alvarez S, Law HCH, Woods NT, Natarajan A. Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax. Bioorganic & Medicinal Chemistry Letters. 128061. PMID 33895280 DOI: 10.1016/j.bmcl.2021.128061 |
0.569 |
|
2019 |
Kour S, Rana S, Contreras JI, King HM, Robb CM, Sonawane YA, Bendjennat M, Crawford AJ, Barger CJ, Kizhake S, Luo X, Hollingsworth MA, Natarajan A. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax. Molecular Pharmacology. 96: 419-429. PMID 31467029 DOI: 10.1124/Mol.119.116855 |
0.759 |
|
2019 |
Kour S, Rana S, Contreras JI, King HM, Robb CM, Sonawane YA, Bendjennat M, Crawford AJ, Barger CJ, Kizhake S, Luo X, Hollingsworth MA, Natarajan A. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax. Molecular Pharmacology. 96: 419-429. PMID 31467029 DOI: 10.1124/Mol.119.116855 |
0.759 |
|
2019 |
Rana S, Bendjennat M, Kour S, King HM, Kizhake S, Zahid M, Natarajan A. Selective degradation of CDK6 by a palbociclib based PROTAC. Bioorganic & Medicinal Chemistry Letters. PMID 30935795 DOI: 10.1016/J.Bmcl.2019.03.035 |
0.796 |
|
2019 |
Rana S, Bendjennat M, Kour S, King HM, Kizhake S, Zahid M, Natarajan A. Selective degradation of CDK6 by a palbociclib based PROTAC. Bioorganic & Medicinal Chemistry Letters. PMID 30935795 DOI: 10.1016/J.Bmcl.2019.03.035 |
0.796 |
|
2018 |
Contreras JI, Robb CM, King HM, Baxter J, Crawford AJ, Kour S, Kizhake S, Sonawane YA, Rana S, Hollingsworth MA, Luo X, Natarajan A. Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy. Acs Chemical Biology. PMID 29608269 DOI: 10.1021/Acschembio.8B00077 |
0.756 |
|
2018 |
Contreras JI, Robb CM, King HM, Baxter J, Crawford AJ, Kour S, Kizhake S, Sonawane YA, Rana S, Hollingsworth MA, Luo X, Natarajan A. Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy. Acs Chemical Biology. PMID 29608269 DOI: 10.1021/Acschembio.8B00077 |
0.756 |
|
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